Medicine and Health Sciences Commons^™

Evidence Facilitating Culture Change: Should Everyone Have Routine Supplemental Oxygen?, Tamara Miller

Nursing Posters

To evaluate the use of routinely administered supplemental oxygen in postoperative total joint replacement patients compared to like patients who had not had supplemental oxygen applied routinely as measured by SpO2.

Expanding The Concept Of Presence During Radiation Therapy Treatment, Carol Thelen

Nursing Posters

Background: Radiation Oncology is an invasive invisible process often given during a time that both patients and their families feel considerable burden. The acute phase of treatment after diagnosis is a time of uncertainty, fear and anxiety. The psychological impacts of this fear and anxiety reduce patient's ability to take in all of the information they are given. Families are often active participants in supporting patients as a second set of eyes and ears. There are no national or organizational guidelines on family presence during radiation treatment. Coborn Cancer Center's practice is not consistent but generally included family waiting in …

Wiki's And Ebp: Linking Academia And Practice, Susan Schleper, Joyce Simones, Rachelle Larsen, Judy Gilsdorf-Gracie

Nursing Posters

To evaluate the advantages and disadvantages of using a Wiki to develop an evidence-based practice research project.

Distress Screening, Jolene Dickerman

Nursing Posters

The purpose of this project is to implement an evidence-based distress screening tool and referral process to support patients diagnosed with cancer. Evaluations of success will include comparison of patient satisfaction and distress level changes over time.

Reduction Of Erosion Risk In Adult Patients With Implanted Ports, Mary K. Weis, Jennifer Burris, Joannie Nei, Hoang D. Nguyen, Bob Miller, Mary Super, Brenda Swendra-Henry, Roxanne Wilson

Nursing Posters

To reduce the percent of port erosion per year to at or below the number reported in the literature.

The Use Of Simulation In Staff Preparation For A New Environment Of Care, Centracare Health

Nursing Posters

Overview: The use of experiential learning in the form of simulation enabled our staff to prepare to coordinate and deliver care during a department move and within the new environment.

The Task: Planning and execution of simulation as a staff training modality for a complete patient department move into a newly constructed environment of care encompassing training of new technology systems including call light and infant security systems, new equipment, and expanded physical space from

National Athletic Trainers' Association Position Statement: Anabolic-Androgenic Steroids, Robert D. Kersey, Diane L. Elliot, Linn Goldberg, Gen Kanayama, James E. Leone, Mike Pavlovich, Harrison G. Pope

Movement Arts, Health Promotion and Leisure Studies Faculty Publications

Objective: This manuscript summarizes the best available scholarly evidence related to anabolic-androgenic steroids (AAS) as a reference for health care professionals, including athletic trainers, educators, and interested others.

Background: Health care professionals associated with sports or exercise should understand and be prepared to educate others about AAS. These synthetic, testosteronebased derivatives are widely abused by athletes and nonathletes to gain athletic performance advantages, develop their physiques, and improve their body image. Although AAS can be ergogenic, their abuse may lead to numerous negative health effects.

Recommendations: Abusers of AAS often rely on questionable information sources. Sports medicine professionals can therefore …

Faith And Masculinity: A Discussion On Raising Awareness And Promoting Cancer Screening Among Latino Men, Michael J. Rovito, James E. Leone

Movement Arts, Health Promotion and Leisure Studies Faculty Publications

Males may experience several barriers to seeking health care, including unfamiliarity with procedures (e.g. colonoscopy), stigma and fear of a given health issue, perceived breach of masculinity (machismo), and fear of feeling vulnerable. Evidence suggests church-based interventions are an effective way to strengthen the connection between promotional message content and participant conceptualization of the risks and benefits of health screenings. However, there is a lack of evidence demonstrating such effectiveness in men’s health, and there is even more of a dearth of research focusing on Latinos. This discussion presents trends from a series of 4 community-based seminars during the 2010-2011 …

A Comparison Of Long-Term Mortality For Off-Pump And On- Pump Coronary Artery Bypass Graft Surgery, Stephen J. Lahey

Articles - Patient Care

Abstract

Background

The survival difference between off-pump and on-pump coronary artery bypass graft (CABG) surgery for follow-up longer than 5 years is not well understood. The objective of this study is to examine the difference in 7-year mortality after these two procedures.

Methods and Results

New York State’s Cardiac Surgery Reporting System was used to identify the 2,640 off-pump and 5,940 on-pump isolated CABG patients discharged from July through December, 2000. The National Death Index was used to ascertain patients’ vital statuses through 2007. A logistic regression model was fit to predict the probability of receiving an off-pump procedure using …

Dentigerous Cyst, Aditya Tadinada

SoDM Presentations

Dentigerous Cyst

Dental School Radiology Presentation : Dentigerous Cyst

Author : Tadinada, Aditya

Medical Subject : Dentigerous Cyst, Odontogenic Cysts

Clinical Presentation Description : Radiolucency arising from the CEJ of an unerupted tooth

Location of Abnormality : Posterior Mandible

Radiological Features : Radiolucency arising from the CEJ of an unerupted tooth

DDx Description : Dentigerous cyst, odontogenic keratocyst, ameloblastoma

Type of Image : Panoramic Radiograph

Digital Publisher : UCONN Health Center : Kilham, Jessica

Format : jpg

Date : 2012

Why There Is No Duty To Die, Gary W. Levvis, Margaret M. Levvis

Torrington Articles

John Hardwig argues that patients have a duty to end their lives when their continued existence imposes serious hardship on their caregivers. Hardwig has deflected many critics’ objections concerning the practical implications of his position. Our goal is to demonstrate the self-contradictory nature of the duty-to-die thesis. Once we eliminate the vagueness (over the essential conditions subtending a presumed duty to die) and the ambiguity (implicit in Hardwig’s use of the term “duty”), we find that the essential conditions for such a duty cannot be simultaneously satisfied. The problem is that the very process by which the duty to die …

Genomic Instability Measured By Inter-(Simple Sequence Repeat) Pcr And High-Resolution Microsatellite Instability Are Prognostic Of Colorectal Carcinoma Survival After Surgical Resection, Bruce M. Brenner, Helen Swede

UCHC Articles - Research

Background

During the multiyear progression to colorectal cancer, numerous genomic alterations arise in events ranging from single base mutations to gains or losses of entire chromosomes. A single genetic change might not stand out as an independent predictor of outcome. The goal of this study was to determine if more comprehensive measurements of genomic instability provide clinically relevant prognostic information.

Methods

Our study included 65 sporadic colorectal cancer patients diagnosed from 1987 to 1991 with last follow-up ascertained in 2006. We estimated an overall tally of alterations using the genome-wide sampling technique of inter-(simple sequence repeat [SSR]) polymerase chain reaction …

Fabrication Of Immunosensor Microwell Arrays From Gold Compact Discs For Detection Of Cancer Biomarker Proteins, Chi K. Tang, Abhay Vaze, James F. Rusling

UCHC Articles - Research

A simple method is reported to fabricate gold arrays featuring microwells surrounding 8-electrodes from gold compact discs (CDs) for less than $0.2 per chip. Integration of these disposable gold CD array chips with microfluidics provided inexpensive immunoarrays that were used to measure a cancer biomarker protein quickly at high sensitivity. The gold CD sensor arrays were fabricated using thermal transfer of laserjet toner from a computer-printed pattern followed by selective chemical etching. Sensor elements had an electrochemically addressable surface area of 0.42 mm² with RSD <2%. For a proof-of-concept application, the arrays were integrated into a simple microfluidic device for electrochemical detection of cancer biomarker interleukin-6 (IL-6) in diluted serum. Capture antibodies of IL-6 were chemically linked onto the electrode arrays and a sandwich immunoassay protocol was developed. A biotinylated detection antibody with polymerized horseradish peroxidase labels was used for signal amplification. The detection limit of IL-6 in diluted serum was remarkably low at 10 fg mL ⁻¹ (385 aM) with a linear response with log of IL-6 concentration from 10 …

Two Novel Large Ankh Deletion Mutations In Sporadic Cases With Craniometaphyseal Dysplasia, Elaine H. Dutra, I-Ping Chen, Ernst J. Reichenberger

UCHC Articles - Research

Craniometaphyseal dysplasia (CMD; OMIM #123000) is a rare genetic disorder characterized by hyperostosis of craniofacial bones and metaphyseal flaring of long bones. Progressive bone thickening causes foraminal stenosis, which leads to the compression of cranial nerves and resultant facial palsy, hearing loss, and blindness. CMD is inherited as an autosomal dominant trait or occurs sporadically with apparent de novo mutations (1, 2). Here, we present two novel large deletions in exons 7 and 10 of ANKH from two unrelated patients without the family history of CMD manifesting severe forms of the disorder.

Of Ticks, Mice And Men: Understanding The Dual-Host Lifestyle Of Lyme Disease Spirochaetes, Justin D. Radolf, Melissa J. Caimano

UCHC Articles - Research

In little more than 30 years, Lyme disease, which is caused by the spirochaete Borrelia burgdorferi, has risen from relative obscurity to become a global public health problem and a prototype of an emerging infection. During this period, there has been an extraordinary accumulation of knowledge on the phylogenetic diversity, molecular biology, genetics and host interactions of B. burgdorferi. In this Review, we integrate this large body of information into a cohesive picture of the molecular and cellular events that transpire as Lyme disease spirochaetes transit between their arthropod and vertebrate hosts during the enzootic cycle.

The Impact Of Contingency Management On Quality Of Life Among Cocaine Abusers With And Without Alcohol Dependence, Nancy M. Petry, Sheila M. Alessi, Leonardo F. Andrade

UCHC Articles - Research

The use of quality of life measures (QOL) in substance abuse treatment research is important because it may lead to a broader understanding of patients’ health status and effects of interventions. Despite the high rates of comorbid cocaine and alcohol use disorders, little is known about the QOL of this population, and even less about the impact of an efficacious behavioral treatment, contingency management (CM), on QOL. In this study, data from three clinical trials were retrospectively analyzed to examine QOL in outpatient cocaine abusers with and without alcohol dependence (AD) and the impact of CM on QOL over time …

Are Baby Boomers Who Care For Their Older Parents Planning For Their Own Future Long-Term Care Needs?, Alison Kleppinger, Julie T. Robison

UCHC Articles - Research

A rapidly expanding number of baby boomers provide care to aging parents. This study examines associations between caregiver status and outcomes related to awareness and anticipation of future long-term care (LTC) needs using 2007 Connecticut Long-Term Care Needs Assessment survey data. Baby boomers who were adult child caregivers (n = 353) vs. baby boomers who were not (n = 1242) were more likely to anticipate some future LTC needs and to have considered certain financing strategies. Although baby boomer adult child caregivers more readily anticipate some future LTC needs, they are not taking specific actions. It is important to address …

Upregulation Of Fibronectin And The Α5Β1 And Αvβ3 Integrins On Blood Vessels Within The Cerebral Ischemic Penumbra, Louise D. Mccullough, Fudong Liu

UCHC Articles - Research

Following focal cerebral ischemia, blood vessels in the ischemic border, or penumbra, launch an angiogenic response. In light of the critical role for fibronectin in angiogenesis, and the observation that fibronectin and its integrin receptors are strongly upregulated on angiogenic vessels in the hypoxic CNS, the aim of this study was to establish whether angiogenic vessels in the ischemic CNS also show this response. Focal cerebral ischemia was established in C57/Bl6 mice by middle cerebral artery occlusion (MCA:O), and brain tissue analyzed seven days following re-perfusion, a time at which angiogenesis is ongoing. Within the ischemic core, immunofluorescent (IF) studies …

Bone Tissue Engineering: Recent Advances And Challenges, Ami R. Amini, Cato T. Laurencin, Syam P. Nukavarapu

UCHC Articles - Research

The worldwide incidence of bone disorders and conditions has trended steeply upward and is expected to double by 2020, especially in populations where aging is coupled with increased obesity and poor physical activity. Engineered bone tissue has been viewed as a potential alternative to the conventional use of bone grafts, due to their limitless supply and no disease transmission. However, bone tissue engineering practices have not proceeded to clinical practice due to several limitations or challenges. Bone tissue engineering aims to induce new functional bone regeneration via the synergistic combination of biomaterials, cells, and factor therapy. In this review, we …

An Open-Source Sandbox For Increasing The Accessibility Of Functional Programming To The Bioinformatics And Scientific Communities, Matthew Fenwick, Colbert Sesanker, Jay Vyas, Michael R. Gryk

UCHC Articles - Research

Scientists are continually faced with the need to express complex mathematical notions in code. The renaissance of functional languages such as LISP and Haskell is often credited to their ability to implement complex data operations and mathematical constructs in an expressive and natural idiom. The slow adoption of functional computing in the scientific community does not, however, reflect the congeniality of these fields. Unfortunately, the learning curve for adoption of functional programming techniques is steeper than that for more traditional languages in the scientific community, such as Python and Java, and this is partially due to the relative sparseness of …

Analyzing Healthy Lifestyle Initiatives For Seniors: A Descriptive Study Of Senior Centers In Montgomery County, Ohio, Abhinav Rajpal

Master of Public Health Program Student Publications

The population of the elderly is expected to rise due to an increase in life expectancy and the aging baby boomer population. This increase in the elderly population will likely cause a burden on the health care system. This burden can be mitigated by promoting healthy lifestyles such as increased physical activity, healthy eating, and tobacco cessation in the elderly. Additionally, by participating in healthy behaviors, seniors can significantly improve their quality of life. Senior centers are at the forefront of promoting healthy lifestyles for the elderly. By promoting physical, social, and mental well-being, senior centers act as a focal …

Health Enhancing Policies And Environments In Select Montgomery County Senior Centers, Stacey L. Gardner

Master of Public Health Program Student Publications

As the baby boomer generation reaches elderly status, healthcare expenditures in the United States continue to rise. Contributing to healthcare costs is the high prevalence of chronic diseases caused by unhealthy habits of Americans such as tobacco use, lack of physical activity, and consumption of a poor diet. Many chronic diseases can be prevented by engaging in healthier behaviors. Communities and organizations can shift social norms and affect behaviors through policy intervention and environmental strategies. The purpose of this study was to describe policies and environments that foster healthy lifestyles in select senior centers in Montgomery County, Ohio. Specifically, this …

Review Of Civil-Military Coordination In Local Disaster Response, Wilfredo J. Nieves

Master of Public Health Program Student Publications

Background: Globally, disasters affect over 200 million people annually. Governments at all levels attempt to mitigate the effects of disasters by providing training and resources to responders in the event of a disaster. When the disaster is of sufficient magnitude, those that respond will require additional resources to adequately attend to disaster victims. County emergency managers assist in making needed additional resources available. Department of Defense (DoD) installations are sources where emergency management agency (EMA) directors may request assistance. The purpose of this research is to understand the resources legal authority available to civilian emergency managers of Ohio Counties in …

Flight Physician - January, 2012, Civil Aviation Medical Association

Browse all Civil Aviation Medical Association Newsletters

A sixteen page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

Mice Deficient In Gem Gtpase Show Abnormal Glucose Homeostasis Due To Defects In Beta-Cell Calcium Handling, Jenny E. Gunton, Mary Sisavanh, Rebecca A. Stokes, Jon Satin, Leslie S. Satin, Min Zhang, Sue M. Liu, Weikang Cai, Kim Cheng, Gregory J. Cooney, D. Ross Laybutt, Trina So, Juan-Carlos Molero, Shane T. Grey, Douglas A. Andres, Michael S. Rolph, Charles R. Mackay

Pharmacology and Toxicology Publications

Aims and Hypothesis

Glucose-stimulated insulin secretion from beta-cells is a tightly regulated process that requires calcium flux to trigger exocytosis of insulin-containing vesicles. Regulation of calcium handling in beta-cells remains incompletely understood. Gem, a member of the RGK (Rad/Gem/Kir) family regulates calcium channel handling in other cell types, and Gem over-expression inhibits insulin release in insulin-secreting Min6 cells. The aim of this study was to explore the role of Gem in insulin secretion. We hypothesised that Gem may regulate insulin secretion and thus affect glucose tolerance in vivo.

Methods

Gem-deficient mice were generated and their metabolic phenotype characterised by …

Atrazine Exposure In Public Drinking Water And Preterm Birth, Jessica L. Rinsky, Claudia Hopenhayn, Vijay Golla, Steven R. Browning, Heather M. Bush

Epidemiology and Environmental Health Faculty Publications

Objectives

Approximately 13% of all births occur prior to 37 weeks gestation in the U.S. Some established risk factors exist for preterm birth, but the etiology remains largely unknown. Recent studies have suggested an association with environmental exposures. We examined the relationship between preterm birth and exposure to a commonly used herbicide, atrazine, in drinking water.

Methods

We reviewed Kentucky birth certificate data for 2004–2006 to collect duration of pregnancy and other individual-level covariates. We assessed existing data sources for atrazine levels in public drinking water for the years 2000–2008, classifying maternal county of residence into three atrazine exposure groups. …

Aging And The Motor Unit, J. Bunn

Physical Therapy

No abstract provided.

Preventing Muscle Atrophy With Protein And Amino Acid Supplementation, J. Bunn

Physical Therapy

No abstract provided.

Reliability Of A Seated Three-Dimensional Passive Intervertebral Motion Test For Mobility, End-Feel, And Pain Provocation In Patients With Cervicalgia, D. M. Manning, G. S. Dedrick, P. S. Sizer, J. M. Brismée

Physical Therapy

No abstract provided.

Chronic Female Pelvic Pain; Part Ii: Differential Diagnosis And Management, P. Nelson, G. Apte, R. Justiz, J. M. Brismée, G. S. Dedrick, P. S. Sizer

Physical Therapy

No abstract provided.