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Articles 1 - 30 of 215
Full-Text Articles in Medicine and Health Sciences
Mode Of Delivery And Birth Complications In Fetal Macrosomia: A Simple Cost-Effectiveness Analysis, Batuhan Özmen, Yavuz Emre Şükür, Tuncay Yüce, Vugar Bayramov, Hülya Olmuş, Murat Sönmezer, Cem Somer Atabekoğlu
Mode Of Delivery And Birth Complications In Fetal Macrosomia: A Simple Cost-Effectiveness Analysis, Batuhan Özmen, Yavuz Emre Şükür, Tuncay Yüce, Vugar Bayramov, Hülya Olmuş, Murat Sönmezer, Cem Somer Atabekoğlu
Turkish Journal of Medical Sciences
To evaluate the effect of delivery route on birth complications and related costs in fetal macrosomia (>4000 g). Materials and methods: Patient and newborn hospital records of 365 macrosomic deliveries (≥4000 g) were retrospectively analyzed. Of these deliveries, 189 newborns weighed between 4000 and 4249 g (Group I), and 176 were between 4250 and 4500 g (Group II). The effects of mode of delivery on birth complications were evaluated and a simple cost-effectiveness analysis was performed. Results: There was no statistical difference between the 2 groups concerning birth complications, except dystocia and episiotomy hematoma. The rate of dystocia was …
Primary Anorectal Malignant Melanoma: Rare But Highly Lethal Malignancy, Özlem Sönmez, Ümmügül Üyetürk, Kaan Helvaci, İbrahi̇m Türker, Fahri̇ye Tuğba Köş, Lütfi̇ Doğan, Burçi̇n Budakoğlu, Ülkü Yalçintaş Arslan, Ömür Berna Çakmak Öksüzoğlu
Primary Anorectal Malignant Melanoma: Rare But Highly Lethal Malignancy, Özlem Sönmez, Ümmügül Üyetürk, Kaan Helvaci, İbrahi̇m Türker, Fahri̇ye Tuğba Köş, Lütfi̇ Doğan, Burçi̇n Budakoğlu, Ülkü Yalçintaş Arslan, Ömür Berna Çakmak Öksüzoğlu
Turkish Journal of Medical Sciences
Primary anorectal malignant melanoma (MM) is a rare but highly lethal malignancy. The aim of this study was to present an overview of the clinical features and treatment strategies in patients with anorectal MM. Materials and methods: Nine patients who were diagnosed with anorectal MM between 1998 and 2010 were reviewed retrospectively. Results: The median age of the patients was 51 years (range: 28-75). The sex ratio of male to female was 1:2. The main presenting symptom was rectal bleeding. At the time of diagnosis, 1 patient was stage IV and 8 patients were stage III. All of the patients …
Sigmoid Volvulus In Pregnancy, Sabri̇ Selçuk Atamanalp, Gürkan Öztürk
Sigmoid Volvulus In Pregnancy, Sabri̇ Selçuk Atamanalp, Gürkan Öztürk
Turkish Journal of Medical Sciences
To review the clinical outcomes of 9 patients with sigmoid volvulus (SV), a rare complication during pregnancy. Materials and methods: The clinical records of the patients were reviewed retrospectively. Results: The age range of the patients was 24-39 years (mean: 30.6 years). All patients were multiparous, and 6 patients (66.7%) were in the third trimester when diagnosed with SV. The main clinical features were abdominal pain/tenderness, obstipation, and distention in all patients (100.0%). The correct diagnosis was achieved based on clinical examination in 66.7% of the cases. Endoscopic detorsion was attempted in 6 patients (66.7%), with an 83.3% success rate. …
The Relationship Between Symptoms And The Results Of The Skin Prick Test In Patients With Allergic Rhinitis, Hayri̇ye Karabulut, Emre Günbey, Mehmet Ali̇ Babademez, Baran Acar, Emrah Çeli̇k, Tevfi̇k Pinar, Riza Murat Karaşen
The Relationship Between Symptoms And The Results Of The Skin Prick Test In Patients With Allergic Rhinitis, Hayri̇ye Karabulut, Emre Günbey, Mehmet Ali̇ Babademez, Baran Acar, Emrah Çeli̇k, Tevfi̇k Pinar, Riza Murat Karaşen
Turkish Journal of Medical Sciences
To determine the relationship between skin prick test results and allergic symptoms and to discover which symptom or symptoms are more commonly associated with the skin prick test. Materials and methods: Of the 1462 patients with a prediagnosis of allergic rhinitis (AR) who underwent the skin prick test, 495 subjects completed the symptoms inquiry form and were included in the study. Results: Out of 495 cases, the skin prick test was found to be positive in 358 and negative in 137. No significant relationship was found between sneezing, runny nose, itchy nose, nasal obstruction, headache, postnasal drip, and skin prick …
A Study On Molecular Characterization Of Macrolide Resistance Mechanism Among Isolates Of Streptococcus Pneumoniae From The Southern Marmara Region Of Turkey, As Well As Resistance To Macrolides And Penicillin In These Isolates, Cüneyt Özakin, Hi̇cran Güler, Emel Gürcüoğlu, Sali̇ha Bakir Özbey, Esra Kazak, Ayşe Melda Sinirtaş
A Study On Molecular Characterization Of Macrolide Resistance Mechanism Among Isolates Of Streptococcus Pneumoniae From The Southern Marmara Region Of Turkey, As Well As Resistance To Macrolides And Penicillin In These Isolates, Cüneyt Özakin, Hi̇cran Güler, Emel Gürcüoğlu, Sali̇ha Bakir Özbey, Esra Kazak, Ayşe Melda Sinirtaş
Turkish Journal of Medical Sciences
To determine the distribution of macrolide resistance genes as well as resistance rates in isolated Streptococcus pneumoniae strains from the southern Marmara region of Turkey. Materials and methods: Antimicrobial resistance rates and MIC values were determined by the E-test method in 300 Streptococcus pneumoniae isolates that were isolated from clinical samples. Resistance genes were determined by the polymerase chain reaction (PCR) method in erythromycin-resistant strains. Results: It was found that 11.4% of Streptococcus pneumoniae isolates were resistant to macrolides. The penicillin MIC value was >=0.12 µg/mL in 23% of the strains and 2 µg/mL in 2% of the strains. The …
Contribution Of Phospholipase C And Protein Kinase C But Not Endothelin-Converting Enzyme To Contractile Responses Of Ethanol, Naci̇ye Döndaş, Hali̇l Mahi̇r Kaplan, Derya Kaya, Erği̇n Şi̇ngi̇ri̇k
Contribution Of Phospholipase C And Protein Kinase C But Not Endothelin-Converting Enzyme To Contractile Responses Of Ethanol, Naci̇ye Döndaş, Hali̇l Mahi̇r Kaplan, Derya Kaya, Erği̇n Şi̇ngi̇ri̇k
Turkish Journal of Medical Sciences
Aim: To evaluate the possible roles of phospholipase C, protein kinase C, and endothelin-converting enzyme on contractions induced by ethanol (164 mM) in isolated gastric fundal strips of mice. Materials and methods: After the mice were killed, the stomach of each was removed and longitudinal muscle strips were prepared from the gastric fundus. The strips were mounted in organ baths and their responses were recorded isometrically. Ethanol (164 mM) was added to the organ baths and a steady-state contraction was obtained. After the first ethanol response was recorded, the preparations were incubated separately with lidocaine (1-100 µM), neomycin (10-500 µM), …
Evaluation Of The Antibacterial Activity Of Zataria Multiflora Boiss., Rhus Coriaria L. (Sumac), Mentha Piperita L., And Ocimum Basilicum L. Extracts On Brucella Strains Isolated From Brucellosis Patients, Yousef Motaharinia, Mohammad Ali Rezaee, Mohammad Saleh Hazhir, Farid Zandi, Reza Shapouri, Mohammad Saied Hakhamaneshi, Ahmad Rashidi, Mohammad Reza Rahmani
Evaluation Of The Antibacterial Activity Of Zataria Multiflora Boiss., Rhus Coriaria L. (Sumac), Mentha Piperita L., And Ocimum Basilicum L. Extracts On Brucella Strains Isolated From Brucellosis Patients, Yousef Motaharinia, Mohammad Ali Rezaee, Mohammad Saleh Hazhir, Farid Zandi, Reza Shapouri, Mohammad Saied Hakhamaneshi, Ahmad Rashidi, Mohammad Reza Rahmani
Turkish Journal of Medical Sciences
Since brucellosis has been called a chronic illness and treatment of patients infected with this bacterium has not been successful, the present study aim ed to evaluate the effects of several medicinal plant extracts on clinical Brucella strains. Materials and methods: First, Brucella strains were isolated from brucellosis patients. Then an antibiotic resistance assay was performed for these strains, while the antibacterial activity of the above-mentioned extracts was evaluated. Results: After performing accurate evaluations, the obtained results showed that all of the isolated Brucella strains were sensitive to tetracycline, doxycycline, and gentamicin, and the rates of antibiotic resistance to rifampin …
Prediction Of Mortality In Stroke Patients Using Multilayer Perceptron Neural Networks, Necdet Süt, Yahya Çeli̇k
Prediction Of Mortality In Stroke Patients Using Multilayer Perceptron Neural Networks, Necdet Süt, Yahya Çeli̇k
Turkish Journal of Medical Sciences
We aim ed to predict mortality in stroke patients by using multilayer perceptron (MLP) neural networks. Materials and methods: A data set consisting of 584 stroke patients was analyzed using MLP neural networks. The effect of prognostic factors (age, hospitalization time, sex, hypertension, atrial fibrillation, embolism, stroke type, infection, diabetes mellitus, and ischemic heart disease) on mortality in stroke were trained with 6 different MLP algorithms [quick propagation (QP), Levenberg-Marquardt (LM), backpropagation (BP), quasi-Newton (QN), delta bar delta (DBD), and conjugate gradient descent (CGD)]. The performances of the MLP neural network algorithms were compared using the receiver operating characteristic (ROC) …
Rating Of Perceived Exertion In Cycle Ergometer: Effect Of Maximal Capacity Difference, Özgür Kasimay Çakir, Bariş Çakir, Ömer Utku Erzengi̇n, Hizir Kurtel
Rating Of Perceived Exertion In Cycle Ergometer: Effect Of Maximal Capacity Difference, Özgür Kasimay Çakir, Bariş Çakir, Ömer Utku Erzengi̇n, Hizir Kurtel
Turkish Journal of Medical Sciences
The purpose of this study was to evaluate cardiopulmonary responses of individuals with different fitness levels according to predetermined rating of perceived exertion (RPE) scores and to investigate the correspondence between the heart rate reserve percentage (HRR%) and the RPE scale by using fit and unfit subjects. Materials and methods: RPE scores of sedentary volunteers were recorded at different HRR% levels during graded exercise tests on a cycle ergometer. Following the tests, subjects were divided into 2 groups, high metabolic equivalent [(MET) MET >= 10; n = 9] and low MET (MET < 10; n = 11), according to maximal O_2 uptakes (VO_{2max}). Participants performed the steady-state exercise test at the 13th-14th level of their perceived exertion 48 h after the first test. Variance and regression analyses were performed. Results: For all HRR% values, RPE levels were not different between groups. During the graded exercise test, perceived exertion was significantly higher in the low MET group than in the high MET group. Predetermined RPE score results were significantly greater in the low MET group with relative O2 consumption as compared to the high MET group (P < 0.05-0.001). Conclusion: In individuals with different VO_{2max} levels, exercise intensity can be prescribed using HRR% or RPE scale methods while adjusting for individual differences in oxygen consumption.
Final Baricity Of Ropivacaine Or Bupivacaine Combined With Fentanyl For Intrathecal Administration, Berri̇n Günaydin, İrfan Güngör, Seval İzdeş
Final Baricity Of Ropivacaine Or Bupivacaine Combined With Fentanyl For Intrathecal Administration, Berri̇n Günaydin, İrfan Güngör, Seval İzdeş
Turkish Journal of Medical Sciences
We determined the baricity of fentanyl-added bupivacaine or ropivacaine with or without dextrose by analyzing the specific gravity for a better understanding of the final baricity of the intrathecal drug combinations that are supposed to be used for surgery.
Do Incubation Temperature, Incubation Time, And Carbon Dioxide Affect The Chromogenic Properties Of Chromagar?, Di̇lek Yeşi̇m Meti̇n, Hüsnü Pullukçu, Süleyha Hi̇lmi̇oğlu Polat, Ramazan İnci̇, Zeki̇ye Emel Tümbay
Do Incubation Temperature, Incubation Time, And Carbon Dioxide Affect The Chromogenic Properties Of Chromagar?, Di̇lek Yeşi̇m Meti̇n, Hüsnü Pullukçu, Süleyha Hi̇lmi̇oğlu Polat, Ramazan İnci̇, Zeki̇ye Emel Tümbay
Turkish Journal of Medical Sciences
On CHROMagar medium Candida species form different colors; thus, the medium enables the differentiation of these species from each other as well as from other Candida species. The aim of this study is to investigate the effect of incubation temperatures, incubation times, and CO_2 on the chromogenic properties of CHROMagar. Materials and methods: A total of 112 strains of Candida spp. were used. A 0.5 McFarland suspension of each strain was inoculated onto CHROMagar with a calibrated loop and incubated at 26 °C and 35 °C for 24-48 h in normal atmosphere and in an atmosphere of 5% CO_2. The …
Evaluation Of The Relationship Between Obstructive Sleep Apnea Syndrome Severity And Cephalometric And Clinical Variables, Süleyman Hakan Tuna, Önder Öztürk, Muhammet Hakan Türkkahraman, Hüseyi̇n Alkiş, Hüseyi̇n Avni̇ Balcioğlu, Ahmet Akkaya
Evaluation Of The Relationship Between Obstructive Sleep Apnea Syndrome Severity And Cephalometric And Clinical Variables, Süleyman Hakan Tuna, Önder Öztürk, Muhammet Hakan Türkkahraman, Hüseyi̇n Alkiş, Hüseyi̇n Avni̇ Balcioğlu, Ahmet Akkaya
Turkish Journal of Medical Sciences
To evaluate the cephalometric features of patients with obstructive sleep apnea syndrome (OSAS) and to elucidate the relationship between the severity of OSAS and cephalometric and clinical variables. Materials and methods: Ninety-three patients (71M/22W) with OSAS were classified into 3 subgroups according to the apnea-hypopnea index (AHI). Various cephalometric and clinical measurements were carried out for all patients. Results: Inferior airway space (IAS), maximum soft palate thickness (MSPT), SNGoGn°, and distance of hyoid bone to mandibular plane (Hy-MPPerp) were found to be higher in severe OSAS for both sexes. Middle airway space, IAS, MSPT, and Hy-MPPerp were correlated positively with …
Hyperactivation Of The Hypothalamo-Pituitary-Adrenocortical Axis In Streptozotocin Diabetic Rats: Effect Of Tinospora Cordifolia (Willd.) And Insulin Therapy, Nagaraja Puranik, Sheela Devi Devi, Kararshaha Kammar
Hyperactivation Of The Hypothalamo-Pituitary-Adrenocortical Axis In Streptozotocin Diabetic Rats: Effect Of Tinospora Cordifolia (Willd.) And Insulin Therapy, Nagaraja Puranik, Sheela Devi Devi, Kararshaha Kammar
Turkish Journal of Medical Sciences
In the present study, we investigated the extent to which changes in corticosterone level and food and water intake behavior occur in diabetes and explored the effect of Tinospora cordifolia extracts and insulin therapy in streptozotocin-induced diabetic rats. Materials and methods: Female albino rats of the inbred Wistar strain (body weight: 180-210 g) were used in this study. Experimental diabetes was induced by injecting freshly prepared streptozotocin once at the dose of 55 mg/kg body weight intravenously in 0.1 M citrate buffer, pH 4.5. The drug was administered orally for 10 days and 30 days in different groups containing 6 …
Better Marital Adjustment Is Associated With Lower Disease Activity In Early Inflammatory Arthritis, Sally Sabry Mustafa, Karl Julian Looper, Margaret Purden, Phyllis Zelkowitz, Murray Baron
Better Marital Adjustment Is Associated With Lower Disease Activity In Early Inflammatory Arthritis, Sally Sabry Mustafa, Karl Julian Looper, Margaret Purden, Phyllis Zelkowitz, Murray Baron
Turkish Journal of Medical Sciences
The aim of this study was to examine the association between marital adjustment and disease outcomes in patients with early inflammatory arthritis. Materials and methods: Patients with average disease duration of 7.66 ± 3.79 months were recruited from a larger early inflammatory arthritis registry, which recorded sociodemographic data and disease characteristics. The acute phase reactant C-reactive protein (CRP) levels were measured and disease activity was estimated using the Disease Activity Score in 28 joints (DAS28). Patient and spouse perceived marital adjustment was assessed by the Dyadic Adjustment Scale (DAS). Results: The study sample consisted of 73 patients living with their …
Evaevaluation Of Glucose Challenge And Oral Glucose Tolerance Test Results In Pregnancy And Estimation Of Prevalence Of Gestational Diabetes Mellitus At Sema Hospital In İstanbul, Ahmet Ruhi̇ Toraman, Ahmet Gürel, Zeynep Ulusal, Gülni̇hal Bülbül, Ayşe Gülçi̇n Demi̇rdöven, Melek Uzun, Ali̇ Özcan, Muzaffer Çakmak
Evaevaluation Of Glucose Challenge And Oral Glucose Tolerance Test Results In Pregnancy And Estimation Of Prevalence Of Gestational Diabetes Mellitus At Sema Hospital In İstanbul, Ahmet Ruhi̇ Toraman, Ahmet Gürel, Zeynep Ulusal, Gülni̇hal Bülbül, Ayşe Gülçi̇n Demi̇rdöven, Melek Uzun, Ali̇ Özcan, Muzaffer Çakmak
Turkish Journal of Medical Sciences
This study was designed to evaluate glucose screening and oral glucose tolerance test results, and to assess the prevalence of gestational diabetes in pregnant patients admitted to our hospital. Materials and methods: This retrospective study was carried out at Sema Hospital in İstanbul, Turkey. The study subjects were recruited between January 2006 and August 2009. A glucose challenge test (GCT) was given to 1681 pregnant women and based on the results 494 went on to take an oral glucose tolerance test (OGTT). A diagnosis of gestational diabetes mellitus (GDM) was made according to the criteria defined by the National Diabetes …
Effect Of Dietary Β-Sitosterol On Fecal Bacterial And Colonic Biotransformation Enzymes In 1,2-Dimethylhydrazine–Induced Colon Carcinogenesis, Albert Baskar Arul, Khalid Al Numair, Mohammed Al Saif, Ignacimuthu Savarimuthu
Effect Of Dietary Β-Sitosterol On Fecal Bacterial And Colonic Biotransformation Enzymes In 1,2-Dimethylhydrazine–Induced Colon Carcinogenesis, Albert Baskar Arul, Khalid Al Numair, Mohammed Al Saif, Ignacimuthu Savarimuthu
Turkish Journal of Medical Sciences
The present study was designed to investigate the modulatory effect of \beta-sitosterol administration on 1,2-dimethylhydrazine (DMH)-induced fecal bacterial and colonic biotransformation enzyme activities. Materials and methods: The chemopreventive potential of \beta-sitosterol in colon carcinogenesis was assessed by injecting DMH (20 mg/kg body weight) subcutaneously into male Wistar rats and supplementing with \beta-sitosterol throughout the experimental period of 16 weeks at 3 different doses (5, 10, and 20 mg/kg body weight). Results: Amplified activities of fecal bacterial (\beta-glucuronidase, \beta-glucosidase, \beta-galactosidase, nitroreductase, hyaluronate lyase, and sulfatase) and colonic biotransformation (\beta-glucuronidase, \beta-glucosidase, \beta-galactosidase, and nitroreductase) enzymes were considered hallmarks of colon carcinogenesis. DMH-induced …
Characterization Of Uropathogenic Escherichia Coli Strains Obtained From Urology Outpatient Clinic Of Ege Medical Faculty In İzmir, Betül Gi̇ray, Füsun Bahri̇ye Uçar, Sabi̇re Şöhret Aydemi̇r
Characterization Of Uropathogenic Escherichia Coli Strains Obtained From Urology Outpatient Clinic Of Ege Medical Faculty In İzmir, Betül Gi̇ray, Füsun Bahri̇ye Uçar, Sabi̇re Şöhret Aydemi̇r
Turkish Journal of Medical Sciences
To identify the papG gene and its allelic variation in uropathogenic Escherichia coli (UPEC) strains isolated from patients with acute pyelonephritis and cystitis. Materials and methods: Seventy-five E. coli strains isolated from patients admitted to the University of Ege Medical Faculty urology outpatient clinic were isolated and identified phenotypically. All of these strains were examined for the papG gene and allelic distribution of this gene with the multiplex polymerase chain reaction technique. Results: papG genes were found in 24 of 75 E. coli strains. Of these 24 strains, 7 (29%) had papG class II only, 8 (33%) had class III …
Transdiaphragmatic Approach To Liver And Lung Hydatid Cysts, Yener Aydin, Mi̇ne Çeli̇k, Ali̇ Bi̇lal Ulaş, Ati̇la Eroğlu
Transdiaphragmatic Approach To Liver And Lung Hydatid Cysts, Yener Aydin, Mi̇ne Çeli̇k, Ali̇ Bi̇lal Ulaş, Ati̇la Eroğlu
Turkish Journal of Medical Sciences
Hydatid cysts are a clinical problem in developing and nondeveloped countries. This study aimed to present lung and liver hydatid cysts that underwent the transdiaphragmatic surgical approach. Materials and methods: The study retrospectively evaluated 50 consecutive patients with lung and liver hydatid cysts who underwent transdiaphragmatic surgical treatment at the authors' clinic between January 1998 and December 2011. Results: Twenty-four (48%) patients were male and 26 (52%) were female. The average age of the patients was 34 ± 21 (3-72). All patients had liver cysts and 37 had lung cysts. Forty-eight of the patients underwent thoracotomies, 1 a laparotomy, and …
Descending Necrotizing Mediastinitis: Increased Mortality Due To Delayed Presentation, Mehmet Muharrem Erol, Ahmet Ural, Hüseyi̇n Melek, Ahmet Sami̇ Bayram, Celal Teki̇nbaş, Cengi̇z Gebi̇teki̇n
Descending Necrotizing Mediastinitis: Increased Mortality Due To Delayed Presentation, Mehmet Muharrem Erol, Ahmet Ural, Hüseyi̇n Melek, Ahmet Sami̇ Bayram, Celal Teki̇nbaş, Cengi̇z Gebi̇teki̇n
Turkish Journal of Medical Sciences
To describe the clinical features of descending necrotizing mediastinitis (DNM) and to outline the diagnostic and therapeutic measures to be taken in its management. Materials and methods: We retrospectively analyzed the data from 13 patients with DNM treated between 2001 and 2012 in 2 tertiary care centers, together with their demographics, diagnostic methods, therapeutic interventions, and clinical outcomes. Results: The patients consisted of 10 males and 3 females, aged from 16 to 72 years (mean age: 44). Odontogenic and tonsillar infections were the probable sources of infection in the majority of cases. Computerized tomography is a crucial imaging modality in …
Circulating Levels Of Igf-I And Igfbp-3 In Gastric Cancer, Konca Altinkaynak, Mehmet Bi̇li̇ci̇, Nuri̇ Bakan, Fati̇h Akçay
Circulating Levels Of Igf-I And Igfbp-3 In Gastric Cancer, Konca Altinkaynak, Mehmet Bi̇li̇ci̇, Nuri̇ Bakan, Fati̇h Akçay
Turkish Journal of Medical Sciences
To explore the causative mechanism of gastric carcinoma and to investigate the roles of circulating IGF-I and IGFBP-3 in gastric cancer. Materials and methods: Serum IGF-I and IGFBP-3 concentrations were measured using a 2-site coated tube immunoradiometric assay. Results: Serum IGF-I and IGFBP-3 values in gastric cancer patients were significantly lower compared to those in the control group. The difference between serum IGF-I/IGFBP-3 in patients and the control group was not significant. Conclusion: The low serum IGF-I and IGFBP-3 levels detected in patients with gastric cancer could be due to decreased synthesis or increased catabolism of IGF-I or both. It …
Mean Platelet Volume As A Marker Of Future Cardiovascular Disease Risk In Pregnant Women With Impaired Fasting Glucose And Impaired Glucose Tolerance, Nermi̇n Köşüş, Aydin Köşüş, Ni̇lgün Turhan
Mean Platelet Volume As A Marker Of Future Cardiovascular Disease Risk In Pregnant Women With Impaired Fasting Glucose And Impaired Glucose Tolerance, Nermi̇n Köşüş, Aydin Köşüş, Ni̇lgün Turhan
Turkish Journal of Medical Sciences
To compare the mean platelet volume (MPV) of pregnant women with mild glycemic disorders with that of healthy pregnant women to find whether these disorders are risk factors for future cardiovascular disease. Materials and methods: Fasting blood glucose and 50-g oral glucose loading were measured. A 100-g, 3-h oral glucose tolerance test was done when plasma glucose was ≥140 mg/dL, following a loading test. According to the test results, 4 groups were formed: control, impaired fasting glucose, false positive loading test, and impaired glucose tolerance. The hematologic parameters were compared in all of the groups. Results: The mean MPV of …
Effects Of Two Different Doses Of Acetylsalicylic Acid On Serum Nitric Oxide, Asymmetric Dimethylarginine, And Homocysteine Levels In Healthy Volunteers*, İdri̇s Mehmetoğlu, Sevi̇l Kurban
Effects Of Two Different Doses Of Acetylsalicylic Acid On Serum Nitric Oxide, Asymmetric Dimethylarginine, And Homocysteine Levels In Healthy Volunteers*, İdri̇s Mehmetoğlu, Sevi̇l Kurban
Turkish Journal of Medical Sciences
To examine the effects of ASA on serum nitric oxide (NO), asymmetric dimethylarginine (ADMA), and homocysteine levels in healthy volunteers. Materials and methods: Totally, 26 apparently healthy volunteers were enrolled in the study. Of the participants, 13 (5F, 8M) received 100 mg of ASA daily and 13 (5F, 8M) received 150 mg of ASA daily for 2 months. Serum NO, ADMA, and homocysteine levels were measured before and 1 and 2 months after ASA treatment Serum NO, ADMA, and homocysteine levels were measured before and 1 and 2 months after ASA treatment. Results: ADMA levels of the group receiving 150 …
The Evaluation Of The Results Of Adjuvant Chemoradiotherapy In Patients With Gastric Cancer: Results From A Single Center In Eastern Anatolia, Mehmet Bi̇li̇ci̇, Sali̇m Başol Teki̇n, Mustafa Kandaz, Keri̇m Çayir, Mustafa Vecdi̇ Erteki̇n, Hi̇lal Kiziltunç Özmen
The Evaluation Of The Results Of Adjuvant Chemoradiotherapy In Patients With Gastric Cancer: Results From A Single Center In Eastern Anatolia, Mehmet Bi̇li̇ci̇, Sali̇m Başol Teki̇n, Mustafa Kandaz, Keri̇m Çayir, Mustafa Vecdi̇ Erteki̇n, Hi̇lal Kiziltunç Özmen
Turkish Journal of Medical Sciences
To evaluate the results of postoperative chemoradiotherapy in patients with gastric cancer. Gastric cancer is an important public health problem in Turkey, especially in the eastern Anatolia region. Surgery is the primary modality for managing early-stage disease, but most patients who undergo a curative resection develop locoregional or distant recurrence. Therefore, the administration of adjuvant treatment in gastric cancer has great importance. Materials and methods: Operated patients with stage IB-IV (M0) gastric cancer were enrolled in this study. A total of 148 patients with gastric cancer who had completed adjuvant chemoradiotherapy were evaluated retrospectively. Total overall survival (OS), disease-free survival …
Seroprevalence Of Major Blood-Borne Infections Among Blood Donors In Kano, Nigeria, Emmanuel Nwankwo, Imoru Momodu, Ismaila Umar, Babashani Musa, Solomon Adeleke
Seroprevalence Of Major Blood-Borne Infections Among Blood Donors In Kano, Nigeria, Emmanuel Nwankwo, Imoru Momodu, Ismaila Umar, Babashani Musa, Solomon Adeleke
Turkish Journal of Medical Sciences
To examine the seroprevalence of common blood infections among blood donors, which remains a major concern in transfusion medicine in Nigeria. Blood transfusion is one of the known therapeutic interventions that cut across a number of clinical disciplines. Materials and methods: The seroprevalences of human immunodeficiency virus (HIV), hepatitis C virus (HCV), hepatitis B surface antigen (HBsAg), and syphilis among 280 blood donors at the Murtala Mohammed Specialist Hospital (MMSH) were determined. The seroprevalences of the pathogens were determined with regard to age, sex, donor category, and occurrence of association pathogens. Between June and December 2008, 276 males (98.6%) and …
Risk Factors And Prognosis In Children Hospitalized Due To Pandemic H1n1 Influenza A Virus Infection In Ankara, Turkey*, Medi̇ne Ayşi̇n Taşar, Yildiz Bi̇lge, Özge Uysal Soyer, Şükran Yildirim, Mustafa Taşar, Fatma İnci̇ Arikan
Risk Factors And Prognosis In Children Hospitalized Due To Pandemic H1n1 Influenza A Virus Infection In Ankara, Turkey*, Medi̇ne Ayşi̇n Taşar, Yildiz Bi̇lge, Özge Uysal Soyer, Şükran Yildirim, Mustafa Taşar, Fatma İnci̇ Arikan
Turkish Journal of Medical Sciences
To describe the demographic characteristics and clinical features in children with influenza A (H1N1) virus infection and to identify risk factors for severe disease or poor prognosis. Following the first tourist-imported case in Turkey on 16 May 2009, the influenza A (H1N1) virus has spread throughout the country. Materials and methods: Children under 18 years of age who were hospitalized for at least 24 h with an influenza-like illness and who had confirmed influenza A (H1N1) virus infection were included in the study. Demographic factors, clinical signs and symptoms, laboratory results, radiographic findings, treatments, and follow-up periods were noted. Results: …
Electrical Fatalities In Ankara Over 11 Years, Ramazan Akçan, Emre Karacaoğlu, Alper Keten, Aysun Balseven Odabaşi, Çi̇ğdem Kanburoğlu, Ali̇ Riza Tümer, Hani̇fe Alkurt-Alkan
Electrical Fatalities In Ankara Over 11 Years, Ramazan Akçan, Emre Karacaoğlu, Alper Keten, Aysun Balseven Odabaşi, Çi̇ğdem Kanburoğlu, Ali̇ Riza Tümer, Hani̇fe Alkurt-Alkan
Turkish Journal of Medical Sciences
Electrical injuries are still responsible for significant morbidity and mortality; however, they are generally preventable with simple safety measures. This study Abstracts to determine the general features of electrical fatalities, and to draw attention of health professionals towards such preventable deaths. Materials and methods: A retrospective evaluation of records of electrocution-related deaths in Ankara, Turkey, was conducted over 11 years (1998-2008). Results: Out of 12,263 autopsy cases, 100 (0.8%) were secondary to electrocution. Most of the victims were male (n = 94; 94%) while only 6 were female. Victims’ age ranged from 1 year to 76 years, with a mean …
Ileosigmoid Knotting In Pregnancy, Sabri̇ Selçuk Atamanalp
Ileosigmoid Knotting In Pregnancy, Sabri̇ Selçuk Atamanalp
Turkish Journal of Medical Sciences
Aim: Ileosigmoid knotting (ISK) is a rare event in pregnancy. This study reviewed the clinical outcomes of 3 pregnant patients with ISK and compared the characteristics of these pregnant women with 16 nonpregnant women. Materials and methods: The clinical records were reviewed retrospectively. Results: Three pregnant patients accounted for 4.2% of 72 total ISK patients and 15.8% of 19 female ISK patients. The ages of the patients were 35, 38, and 31 years (mean: 34.7 years). All of the patients were multiparous. Two patients (66.7%) were in the 3rd trimester and 1 (33.3%) was in the 2nd trimester. The mean …
Comparison Between Intravenous And Thoracic Epidural Analgesia In Single Coronary Artery Bypass Graft Surgery, Nevri̇ye Salman, Fati̇h Tanzer Serter, Hali̇l İbrahi̇m Uçar, Serdar Günaydin, Ali̇ Cem Yorgancioğlu
Comparison Between Intravenous And Thoracic Epidural Analgesia In Single Coronary Artery Bypass Graft Surgery, Nevri̇ye Salman, Fati̇h Tanzer Serter, Hali̇l İbrahi̇m Uçar, Serdar Günaydin, Ali̇ Cem Yorgancioğlu
Turkish Journal of Medical Sciences
Aim: To compare thoracic epidural analgesia with intravenous analgesia in patients who underwent coronary artery bypass grafting surgery. Materials and methods: This retrospective study included 40 patients who had received elective single artery bypass surgery. After general anesthesia, one group was given patient-controlled thoracic epidural analgesia and the other group was given patient-controlled intravenous meperidine analgesia. Patient assessments were performed during the postoperative period and included the duration of hospital stay, pain and sedation scores, ambulation score, atrial fibrillation incidence, and organ morbidities. Results: No differences were detected between the groups in the demographic or intraoperative data. However, a statistically …
A Combination Therapy Of Half-Dose Verteporfin Photodynamic Therapy And Intravitreal Injection Of Ranibizumab For Chronic Central Serous Chorioretinopathy, Yasi̇n Toklu, Hasan Basri̇ Çakmak, Mücella Arikan Yorgun, Şule Berk Ergun, Şaban Şi̇mşek
A Combination Therapy Of Half-Dose Verteporfin Photodynamic Therapy And Intravitreal Injection Of Ranibizumab For Chronic Central Serous Chorioretinopathy, Yasi̇n Toklu, Hasan Basri̇ Çakmak, Mücella Arikan Yorgun, Şule Berk Ergun, Şaban Şi̇mşek
Turkish Journal of Medical Sciences
Aim: To study the combination treatment consisting of half-dose verteporfin photodynamic therapy (PDT) and an intravitreal injection of ranibizumab as a potential treatment for patients with chronic central serous chorioretinopathy (CSC). Materials and methods: Six eyes of 6 patients were studied with fundus examination, fluorescein angiography, and optical coherence tomography to diagnose the maculopathy, monitor the detachments, and localize the choroidal hyperpermeability of the disorder. Half-dose verteporfin PDT was applied to areas of choroidal hyperpermeability and, the following day, 0.5 mg/0.05 mL ranibizumab was injected intravitreally. The patients were observed to determine the anatomic and functional outcomes. Results: The combination …
Effect Of Prenatal Exposure To Cigarette Smoke On The Conduction Of Sensory Nerve Fibers In The Rat, Jumah Shakhanbeh
Effect Of Prenatal Exposure To Cigarette Smoke On The Conduction Of Sensory Nerve Fibers In The Rat, Jumah Shakhanbeh
Turkish Journal of Medical Sciences
Aim: To investigate the effect of prenatal exposure to cigarette smoke (CS) on the conduction of sensory nerve fibers in the adult rat offspring. Materials and methods: Pregnant rats were exposed to CS by inhalation during the gestation period. The saphenous nerve in the adult offspring was exposed in vivo, and the conduction parameters of the threshold, maximum strength of stimulation, conduction velocity, and amplitude of compound action potentials (CAPs) of A\alpha\beta-, A\delta-, and C-fibers were examined. Results: Prenatal exposure to CS induced significant reduction (P < 0.005) in the peak amplitude of CAPs of A\alpha\beta- and A\delta-fibers. The conduction velocity of A\alpha\beta-fibers and C-fibers was significantly (P < 0.025-0.05) increased after prenatal exposure to CS. Conclusion: Prenatal exposure to CS attenuates the conduction of sensory nerve fibers in the rat saphenous nerve.