Medicine and Health Sciences Commons^™

A Comparison Of Three Bicycle Pedal Types And Power Output, Brandon Kuhn

Master's Theses or Doctor of Nursing Practice

The purpose of this study was to examine the power output over a 30-second maximum effort bicycle sprint with three different pedal types; clipless, toe-strap, and flat. The participants for this investigation were eight (7 males and 1 female) mountain bikers with ages between 20 and 55 ( Age = 40) from the Central Kansas Mountain Bike Club. Each participant was required to provide his or her own bicycle and the researchers provided the training stand, Saris CycleOps PowerTap rear wheel, and Garmin Edge 500 cycling computer used for data collection. Testing procedure consisted of a warmup, 30- second maximal …

Investigation Of A Locus On Chromosome 9 For Contributions To Pulmonary Hypertension Syndrome In Broilers, Sriram Krishnamoorthy

Graduate Theses and Dissertations

Although the ascites syndrome in chickens has been investigated for years, it continues to inflict financial losses to the world poultry industry. It is estimated that 8% of the 361 million broiler deaths are due to ascites leading to losses of millions of dollars annually. Efforts to curb the incidence of ascites are typically designed to slow early growth. This limits the birds' ability to show its true genetic potential and impacts later yields. In 1994 lines divergent for susceptibility to ascites were established from a commercial sire line through sibling selection of birds reared at local altitude after testing …

Recombinant Protein Production In Bacillus Species, Isolation And Methionine Production In Methionine-Producing Microorganisms, Suwat Saengkerdsub

Graduate Theses and Dissertations

Linoleic acid isomerase (LAI) is the enzyme that converts linoleic acid to conjugated linoleic acids (CLAs) which appear to be capable of lowering cancer risk and enhancing immunity. There is an interest in developing commercial processes for the production of single isomers of CLA by biotransformation of LA using microbial cells and enzymes. However, the evaluation of these strains suggest that growth and LA isomerase production levels by these anaerobes are insufficient to support economic commercial production of single CLA isomers. A better alternative is to clone the isomerase gene and to generate new production strains using recombinant technology. Bifidobacterium …

Use Of Standardized Mastery Content Assessments Given During The First Year Of A Baccalaureate Nursing Program For Predicting Nclex-Rn Outcomes, Deanna Jan Emory

Graduate Theses and Dissertations

The purpose of this study was to evaluate the relationship between standardized content specific mastery assessments and NCLEX-RN outcomes. Three content-specific standardized assessments testing Fundamentals, Pharmacology and Mental Health concepts were used to explain the dichotomous NCLEX-RN outcome of pass or fail. The three assessments were developed by Assessment Technologies Institute, LLC (ATI). The assessments were administered to baccalaureate nursing students (N = 119) during the first year of a nursing program in one public university over a period of five consecutive semesters. Group comparisons between those passing and those failing NCLEX-RN on the first attempt and correlations were calculated …

Effect Of Light-Cure Initiation Time On Polymerization Efficiency And Orthodontic Bond Strength With A Resin-Modified Glass-Ionomer, J. T. Thomas, H. W. Roberts, L. Diaz, Thomas Gerard Bradley, David W. Berzins

School of Dentistry Faculty Research and Publications

Objectives –  The polymerization and acid–base reactions in resin-modified glass-ionomers (RMGI) are thought to compete with and inhibit one another. To examine the effect of visible light-cure (VLC) delay on the polymerization efficiency and orthodontic bond strength of a dual-cured RMGI.

Setting and Sample Population –  The Orthodontics Graduate Program at Marquette University. An in vitro study utilizing 72 freshly extracted human bicuspid teeth.

Materials and Methods –  A RMGI light-cured immediately, 2.5, 5, or 10 min after mixing comprised the experimental groups. Isothermal and dynamic temperature scan differential scanning calorimetry (DSC) analysis of the RMGI was performed to determine …

Art Therapy Assessment Of Adult Incarcerated Offenders: A Research Proposal For The Assessment Of Locus Of Control, Alecia Perreault

EVMS School of Health Professions Theses & Dissertations

There is a lack of research that combines both art therapy assessment and prison inmates as it relates to locus of control. This is a research proposal that attempts to highlight the need for research with art therapy assessments among the offender population. More specifically, it attempts to correlate art therapy assessments with the assessment of specific traits, like locus of control, as they are typically found in offenders. This thesis reviews literature that is related to the field of art therapy assessment, projective drawing assessment, and the offender population, as well as discusses implications for further study.

Ministry Of Memories: Keys To Pastoral Care Of Non-Cognitive Persons, Reginald Corfield

Doctoral Dissertations and Projects

This work is intended to examine and study the theological and moral reasons to provide pastoral care to persons who have limited or no cognition. Dementia, Alzheimer's, certain other medical conditions and the aging process cause a loss of brain function that affects memory, thinking, behavior and judgment. Most Clergy wrestle with the fact as to whether there is any purpose in ministering to such persons especially when there is no verbal or non-verbal response. This paper involves surveys, research, collection of historical and biblical data and medical science to evaluate the disease process and explore ways in which to …

Emergency Preparedness Nursing, Emily A. Ganjei, Patricia Grimes

Senior Honors Projects

Emergency Preparedness at Newport Hospital

Emily A. Ganjei

Sponsors: Carolyn Hames and Lisa Lima-Tessier, Nursing

The subject of my project is emergency nursing and emergency preparedness in the Emergency Department (ED) of Newport Hospital. I am working alongside Lisa Lima-Tessier, Clinical Nurse Manager of the ED, and Pat Grimes, Assistant Clinical Nurse Manager/Emergency Preparedness Coordinator.

As an undergraduate in the College of Nursing, the topic of emergency preparedness has been discussed in many courses, in particular community health nursing. In community nursing we discussed different types of disaster situations and reviewed hospital policies regarding triage and the nurse’s role in …

Team Spirit: How Three Libraries Are Working To Support Health Sciences Libraries In Liberia, Elaine Martin, James Combs, Anne Linton, Alexandra Gomes, Darcel A. Bryant, Cynthia L. Henderson

Himmelfarb Library Faculty Posters and Presentations

This poster presentation is a collaborative effort of librarians from Lamar Soutter Library, University of Massachusetts Medical School; Himmelfarb Health Sciences Library, The George Washington University; and Louis Stokes Health Sciences Library, Howard University. International medicine initiatives often occur through institution specific efforts. Yet information needs extend across borders and institutions. Three American health sciences libraries have united to support the development of health sciences libraries in Liberia. While separate schools will support undergraduate and graduate medical education initiatives, the libraries are working together to bring current information resources to all health care professionals.

Web-Scale Discovery In An Academic Medical Library: Our Experience With Ebsco's Discovery Service, Jolinda Thompson, Kathe Obrig, Laura E. Abate

Himmelfarb Library Faculty Posters and Presentations

This poster explores the Himmelfarb Health Sciences Library's steps to determine if a highly tailored version of EBSCO's Discovery Service (EDS) aimed at an academic health sciences audience will be an appealing and effective tool for searching the library's collections and to compare its use to that of the library's current federated search tool.

Getting Into The Game: Inaugurating A Clinical Librarian Program, Laura E. Abate, Alexandra Gomes, Anne Linton

Himmelfarb Library Faculty Posters and Presentations

Himmelfarb Health Sciences Library librarians worked closely with the George Washington University internal medicine residency program to provide training and support; however, many residents seemed unaware of the library's collections and services. To strengthen the relationship between the library and the program and to enhance residents' use of information resources, a librarian was assigned to attend the residents' daily morning meeting at least twice each week.

Broadening Our Game: Strengthening E-Professionalism Among Students, Alexandra Gomes, Gisela Butera, Thomas Harrod, Laura E. Abate, Anne Linton

Himmelfarb Library Faculty Posters and Presentations

To describe the initiatives undertaken by Himmelfarb Health Sciences Library to develop curricular modules on various aspects of e-professionalism including social media, copyright, plagiarism, intellectual property, and appropriate computer use.

Recognition For Positive Behavior As A Critical Youth Development Construct: Conceptual Bases And Implications On Youth Service Development, Ben M. F. Law, Andrew M. H. Siu, Daniel T. L. Shek

Pediatrics Faculty Publications

Recognition for positive behavior is an appropriate response of the social environment to elicit desirable external behavior among the youth. Such positive responses, rendered from various social systems, include tangible and intangible reinforcements. The following theories are used to explain the importance of recognizing positive behavior: operational conditioning, observational learning, self-determination, and humanistic perspective. In the current work, culturally and socially desirable behaviors are discussed in detail with reference to Chinese adolescents. Positive behavior recognition is especially important to adolescent development because it promotes identity formation as well as cultivates moral reasoning and social perspective thinking from various social systems. …

Elucidating The Igfbp2 Signaling Pathway In Glioma Development And Progression, Kristen M. Holmes

Dissertations and Theses (Open Access)

Diffuse gliomas are highly lethal central nervous system malignancies which, unfortunately, are the most common primary brain tumor and also the least responsive to the very few therapeutic modalities currently available to treat them. IGFBP2 is a newly recognized oncogene that is operative in multiple cancer types, including glioma, and shows promise for a targeted therapeutic approach. Elevated IGFBP2 expression is present in high-grade glioma and correlates with poor survival. We have previously demonstrated that IGFBP2 induces glioma development and progression in a spontaneous glioma mouse model, which highlighted its significance and potential for future therapy. However, we did not …

Subacromial Impingement Syndrome, Masood Umer, Irfan Qadir, Mohsin Azam

Department of Surgery Docs

Subacromial impingement syndrome (SAIS) represents a spectrum of pathology ranging from subacromial bursitis to rotator cuff tendinopathy and full-thickness rotator cuff tears. The relationship between subacromial impingement and rotator cuff disease in the etiology of rotator cuff injury is a matter of debate. However, the etiology is multi-factorial, and it has been attributed to both extrinsic and intrinsic mechanisms. Management includes physical therapy, injections, and, for some patients, surgery. No high-quality randomized controlled trials are available so far to provide possible evidence for differences in outcome of different treatment strategies. There remains a need for high-quality clinical research on the …

Modeling Of The Efficacy And Effectiveness Of Escherichia Coli O157:H7 Pre-Harvest Interventions, Amanda R. Vogstad

School of Veterinary and Biomedical Sciences: Dissertations, Theses, and Student Research

Shiga toxin-producing Escherichia coli O157:H7 (STEC O157) is one of the leading causes of hemolytic uremic syndrome in humans. Reducing the prevalence of STEC O157 in live cattle may reduce ground beef prevalence and subsequent human illness. Type III secreted protein vaccines (TTSP) reduce fecal shedding of STEC O157 in cattle. However, pre-harvest vaccines have yet to be adopted by the beef industry. The objectives of this thesis were to 1) conduct a meta-analysis to test factors effecting efficacy of a 3-dose regimen TTSP vaccine product, and 2) use stochastic simulation to model the usefulness of preharvest control measures. In …

Breakfast Consumption Habits Of Youth Living In Low Income Neighborhoods In A Large Three County Metropolitan Area, Elijah Dacy

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Purpose: The purpose of this study was to identify youth attitudes, frequency of, and barriers for breakfast consumption and the use of available nutrition programs by youth living in poverty or food insecure households in a large three county metropolitan area. Methods: A phone survey was developed and tested in order to collect information on breakfast consumption habits and attitudes of children, targeted as food insecure. There were no incentives for persons to participate in the survey and all information gathered was kept in a secure place at the Center for Human Nutrition. Participants who were allowed to …

Expression Of Matrix Metalloproteinase-1 In Knee Osteoarthritis: Association With Disease Severity, S Honsawek, J Poonphakdi, B Deepaisarnsakul, A Tanavalee, P Yuktanandana, S Ngarmukos, S. Tantavisut

Chulalongkorn Medical Journal

Background : Osteoarthritis (OA) is characterized by the progressive loss of articular cartilage and osteophyte formation resulting in pain, stiffness, reduced motion, swelling, crepitus, and disability. The aim of this study is to investigate plasma and synovial fluid matrix metalloproteinase-1 (MMP-1) levels of patients with primary knee OA and to examine their relationship with disease severity. Methods : Thirty-two patients aged 53 - 83 years old with knee OA and 10 healthy individuals were recruited into this study. Disease severity was determined using weight-bearing anteroposterior radiographs of the affected knee. The radiological grading of knee OA was performed according to …

Efficacy And Safety Of Diacerein In The Treatment Of Patients With Painful Knee Osteoarthritis: A Modified Regimen, P Yuktanandana, W. Suravech

Chulalongkorn Medical Journal

Background : Recent systematic meta-analyses provide evidence for the efficacy of diacerein 100 mg/day in the treatment of knee and hip osteoarthritis (OA). However, as diacerein may cause acceleration in intestinal transit time during the first 2 weeks of treatment, it is recommended to start with 50 mg/day for 4 weeks then increase the dose to 100 mg/day. However, no study has been performed on the treatment regimen. This study was conducted in order to assess the efficacy of diacerein according to the recommended regimen. Objective : To assess the efficacy and safety of diacerein in reducing pain and functional …

Magnetic Resonance Imaging Based Lumbar Interspinous Distance Measurements In Thai Subjects, S Tantavisut, P Ittiravivong, P Tangpornprasert, C Virulsi, T. Tejapongvorachai

Chulalongkorn Medical Journal

Background : There is no previous report regarding normal lumbar interspinous distance in Thai subjects. The measurement of the lumbar interspinous distance is made based on the magnetic resonance imaging images. Objective : To measure the distance of the lumbar interspinous process in Thai subjects and compare with the size of the currently available interspinous device in Thai market. Methods : Sixty healthy subjects (30 males and 30 females) age 20 - 55 years were enrolled into this study. All of the subjects were underwent the lumbar spine magnetic resonance imaging (MRI). The interspinous distance was measured at the most …

Economic Evaluation Of Nucleoplasty Compared With Conventional Opened Diskectomy In Treatment Of Contained Herniated Lumbar Disk, C Charoenlap, T Tejapongvorachai, S. Kuptniratsaikul

Chulalongkorn Medical Journal

Introduction : Nucleoplasty is a minimally invasive percutaneus lumbar intervertebral disk decompression using coblation energey. The technique is indicated for patients with contained herniated lumbar disk who are unresponsive to conservative management as an alternative treatment. Many recent literatures proved that nucleoplasty is an effective procedure comparable to the standard treatment, but its long-term result is still controversial. Objective : To compare effectiveness between nucleoplasty and conventional opened diskectomy and to evaluate the economical aspects of nucleoplasty Setting : Department of Orthopaedics, King Chulalongkorn Memorial Hospital. Research Design : A non-randomized prospective clinical trial with full economic evaluation Patients : …

Hyperflexion Trauma In The Posttraumatic Nonunion Odontoid Process Fracture: A Case Study, C Chaichankul, W Limthongkul, W. Yingsakmongkol

Chulalongkorn Medical Journal

Os odontoideum is a small round or oval corticated ossicle with a smooth cortical border and no body union to the body of the axis. Posttraumatic injury of the cervical spine is one of the etiologies. We reported a 28-year-old man patient with os odontoideum presented with a trivial hyperflexion cervical trauma. He developed neurogenic shock and central cord syndrome. This case supports the theory that previous trauma is the etiology of the abnormality. Surgical management alleviated his symptom. Occipitocervical fusion with C1 laminectomy was successfully achieved in this case. Odontoid nonunion is a potentially a serious situation. Patients can …

Injury To The Epiphyseal Plate, N. Limpaphayom

Chulalongkorn Medical Journal

Epiphyseal plate or physis is a unique structure of the immature skeleton. It comprises chondrocytes in columnar formation. The chondrocyte maturation process in the physis is the responsible mechanism for longitudinal bone growth through endochondral ossification process. The blood supply to the physis can be divided to two major systems. Understanding of the injury to the physis and the blood supply is crucial for clinicians to effectively treat this particular injury in the childhood and adolescence. Injury classification scheme is based on radiographic appearances which lead to treatment planning and possible subsequent complications. Treatment of the physis injury requires the …

Acromioclavicular Joint Injury, T. Tanpowpong

Chulalongkorn Medical Journal

Acromioclavicular joint injury is common among young active individuals. Stability of this complex structure composes of muscles (deltoid and trapezius), ligaments (acromioclavicular and coracoclavicular) and joint capsule. Clinical and radiographic examinations are crucial for the diagnosis of this injury. Non operative treatment is indicated for type I and II injury. Surgical treatment is, however, indicated for type IV, V and VI injury. Treatment for type III injury is still controversy. Methods of treatment fall into 3 categories, namely: fixation of the acromioclavicular joint, fixation of the coracoclavicular joint and ligament reconstruction. The trend of treatment goes to minimal invasive anatomic …

ย่อวารสาร, N/A

Chulalongkorn Medical Journal

No abstract provided.

แนะนำหนังสือ, N/A

Chulalongkorn Medical Journal

No abstract provided.

The Effect Of Heart Failure Education On Intermediate Care Unit Nursing Staff's Knowledge Of Heart Failure, Self-Care, And Best Practice Guidelines, Carol Budgin

Evidence-Based Practice Project Reports

Heart failure (HF) is a chronic disease affecting nearly six million people in the United States with an annual cost of nearly 33 billion dollars. If nurses are inadequately prepared to care for and/or educate patients with HF, evidence-based (EB) nursing care will be suboptimal and hospital readmission rates with the subsequent increased costs for care will continue to soar. To address their higher-than-national average HF readmission rates, an EB nursing project was implemented at a local, urban community hospital to assess intermediate care unit (IMCU) nursing staff’s knowledge of HF, selfcare, and best practice guidelines. The Rossworm & Larrabee …

The Effect Of Progesterone Only Contraception On The Accuracy Of Cervical Cytologic Interpretation, Michelle Reneé Collins

Theses and Dissertations (ETD)

Abstract Introduction: Papanicolaou screening is the standard of care for the detection of abnormal cervical cells. Early detection and treatment of cervical neoplasia depends on the accurate interpretation of the cytologic sample. Diagnosis of dysplasia is made by histology interpretation to confirm the results of cytology screening. Cervical cells are susceptible to change as a result of hormonal exposure, and this has the potential to affect cytologic interpretation. Cervical cells may be exposed to exogenous progesterone if the woman uses injectable depot medroxyprogesterone acetate or a progesterone intrauterine device. Previous study results have been inconsistent regarding the effect of progesterone …

Cns Penetration Of Tyrosine Kinase Inhibitors In Mouse Models, Mohamed Elmeliegy

Theses and Dissertations (ETD)

For the past three decades, advances in the treatment of central nervous system (CNS) tumors such as malignant glioma have only been modest. One particular challenge facing treatment of brain tumors is the delivery of therapeutically effective concentrations of anti-cancer agents to the target site in the brain. The sanctuary of the brain is protected by several barrier systems such as the blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). These barriers restrict the passage of anti-cancer drugs into the brain via several protective mechanisms.

In the present study, we used cerebral microdialysis sampling, a technique for sampling unbound …

Rankl And Osteoprotegerin Levels In Response To Orthodontic Forces, Katherine Ann Hart D.D.S.

Theses and Dissertations (ETD)

Orthodontic tooth movement is mediated by interactions between PDL cells and those of the alveolus. One protein—the receptor activator nuclear factor kappa B ligand (RANKL)—is critical for osteoclastogenesis, and osteoprotegerin (OPG) is a decoy ligand that competitively inhibits RANKL. A higher RANKL/OPG ratio is associated with areas of bone resorption, while a lower ratio occurs in areas of bone deposition and homeostasis. There have been almost no clinical studies of RANKL and OPG expression in human subjects undergoing orthodontic tooth movement. The purpose of this study was to quantify changes in the levels of RANKL and of OPG expression in …