Medicine and Health Sciences Commons^™

Concepts Of Communication Concerning Medical Services, C. Pancharoen

Chulalongkorn Medical Journal

Communication is an important tool in solving problems concerning medical services. Concepts include patient-centered approach, appropriate use of communication skills, using open questions, avoid bias and routine practice, and caring patients with holistic and humanized concepts.

Pneumonia Due To 2009 Influenza A (H1n1) Infection In Thai Children: Chulalongkorn Experience, R Uppala, N Prapphal, J Deerojanawong, S Sritippayawan, R Samransamruajkit, K. Pongsanon

Chulalongkorn Medical Journal

Objective : To study the clinical presentations and outcomes of 2009 influenza A (H1N1) pneumonia children at King Chulalongkorn Memorial Hospital. Setting : Department of Pediatrics, King Chulalongkorn Memorial Hospital. Research design : Descriptive study. Patients Pediatric patients aged 1 month - 18 years who were admitted due to H1N1 influenza pneumonia between June 2009 - March 2010. Methods : All the pediatric patients with pneumonia who had laboratory confirmation of 2009 influenza A (H1N1) infection by positive real-time reverse-transcriptase polymerase chain reaction (RT-PCR) assay for H1N1 influenza A virus in their nasopharyngeal aspirates or combined nasal and throat swabs …

Effectiveness Of Peak Flow Meter In Management Of Childhood Asthma, T Tunnitisupawong, N Prapphal, J Deerojanawong, S Sritippayawan, R. Samransamraujkit

Chulalongkorn Medical Journal

Objective : To assess the effectiveness of routine use of peak flow meter (PFM) in addition to symptom-based guided self-management of children with asthma. Materials and Method : A prospective randomized controlled trial was performed in patients aged 6 - 15 years with persistent asthma who had been treated with inhaled corticosteroid (ICS) for at least 1 month. The recruited patients were randomized into 2 groups. The first group used PFM in addition to the symptoms assessment in self-management plan (PFM group) while the other group used only symptoms-based management plan (non-PFM group). All patients were evaluated in terms of …

Frequency And Following Study Of Uterine Leiomyoma Variants In Patients Having Surgery At Charoenkrung-Pracharak Hospital, W Anansakunwat, S Yodavudh, Tangjitgamol S, S. Jesadapatarakul

Chulalongkorn Medical Journal

Background : The frequency of uterine leiomyoma variants and smooth muscle tumor of uncertain malignant potential (STUMP) are low. No previously study about them has been done at Charoenkrungpracharak Hospital and in Thailand. Their clinical behaviors are uncertain with some controversies regarding the prognosis including the risk of recurrence. Objective : To investigate the frequency of uterine leiomyoma variants and STUMP and to compare the clinicopathological features and recurrence rate of these variants to typical leiomyoma (LM). Design : A retrospective study. Setting : Charoenkrung-pracharak Hospital, Bangkok Metropolitan Administration. Subjects : One thousand and fifty-two patients with smooth muscle tumor …

Nephrotic Syndrome Associated With Plasmodium Malariae In Infancy : A Case Report, T Deekajorndech, S Boonyasuwat, A Chanakul, P Rianthavorn, P Kingwattanakul, W. Kittikowit

Chulalongkorn Medical Journal

A progressive glomerulonephritis associated with Plasmodium malariae infection is known as quartan malarial nephropathy. This condition occurs only in a small number of patients. We report an 11-month-old infant presenting with generalized edema and proteinuria after having Plasmodium malariae infection.

Anxiety And Depression In Stroke Patients At The Thai Red Cross Rehabilitation Center, S Taveemanoon, K. Sukonthamarn

Chulalongkorn Medical Journal

Background : Post - stroke depression is a common complication and it impedes the recovery and interrupts rehabilitation programs. The study of emotional symptoms in stroke patients on the rehabilitation phase in the rehabilitation center should be evaluated. Objectives : 1. To determine the anxiety and depression symptoms in stroke patients before and after rehabilitation program 2. To identify the associating factors that influence emotional symptoms. Design : Retrospective analytical study Setting : The Thai Red Cross Rehabilitation Center, Samutprakarn Province. Patients : All stroke patients who were admitted to the Thai Red Cross Rehabilitation Center between June 2008 – …

Attitudes And Childcare Functions Of Caregivers In Private Childcare Centers In Lamphun Province, P Sombatmai, P. Chandarasiri

Chulalongkorn Medical Journal

Background : In modern society, a child caregiver has become the main person for giving care to children that performs childcare function like family function. It must be realized in the characteristics of caregivers, especially, the attitudes and childcare functions, which can be influential to the child. So there has been limited that researchers are interested to study on attitude and childcare functions. Objective : To examine the attitude, childcare functions and associated factors among attitudes and performance in the care of children who work in childcare centers of Lamphun Province. Design : A cross – sectional descriptive study. Setting …

Atovaquone Ameliorate Gastrointestinal Toxoplasmosis Complications In A Pregnancy Model, Helieh S. Oz, Thomas Tobin

Physiology Faculty Publications

Background: Toxoplasma is an important source of foodborne hospitalization with no safe and effective therapy against chronic or congenital Toxopalsmosis. Atovaquone is a drug of choice but not approved for use in congenital Toxoplasmosis. We hypothesized atovaquone to be safe and effective against feto-maternal Toxoplasmosis.

Material/Methods: Programmed pregnant mice were i.p. infected with 50–2400 Tachyzoites from Type II strain (clone PTG). Dams were treated daily with atovaquone or sham and monitored for pain, and complications.

Results: Dams developed pain related abdominal hypersensitivity (allodynia) to mechanical stimuli in a Tachyzoites dose dependent manner. Infected dams were anemic and exhibited ascities and …

A Multi-Centric, Double-Blind Randomized, Homoeopathic Pathogenetic Trial Of Buxus Sempervirens, Rajpal Rajpal, Vinay Singh, V Siddiqui, C Nayak, A Majumdar, P Chandra, S Dey, P Sivadas

Indian Journal of Research in Homoeopathy

Objective:To elicit the pathogenetic response of Buxus sempervirens Linn. in homoeopathic potencies on healthy human volunteers. Methodology: Buxus sempervirens drug was proved by the Central Council for Research in Homoeopathy (CCRH) through randomized, double-blind, placebo-controlled method. The proving was conducted at three centres during 2007-08. The drug was proved in 6 & 30 centesimal potencies on 57 apparently healthy volunteers, declared eligible after their pre-trial medical examination by the medical specialists and routine laboratory investigations. In its first phase of proving, volunteers were given 56 doses of placebo divided in 4 doses per day for 14 days. In the next …

Standardisation And Quality Control Of Homoeopathic Drug Pimenta Officinalis Lindl, P Rao, P Subramanian, P Sudhakar, T Reddy, P Reddy, H Gupta

Indian Journal of Research in Homoeopathy

Pimenta officinalis Lindl., a bushy tree commonly known as ′all spice′ belongs to the family Myrtaceae. It is a potential drug in homoeopathy used in neuralgias and disturbed sensations of heat and cold. The dried unripe fruits are used as medicine. The fruit is a small pea-sized berry, blackish to reddish brown. The epicarp is conspicuous with numerous large glandular secretory cavities. The pericarp is about 2 mm thick. The mesocarpic cells contain resin, tannins and sphaerocrystals. Stone cells are also present in mesocarp. The outermost layer of seed consists of closely packed testa with attached stone cells. The endosperm …

Homoeopathic Medicines In The Management Of Benign Prostatic Hyperplasia: A Multicentric Prospective Observational Study, Praveen Oberai, Varanasi Roja, D Ramesh, D Arya, G Reddy, S Sharma, Chaturbhuja Nayak, Vikram Singh, Hari Singh

Indian Journal of Research in Homoeopathy

Objectives:The primary objective of this study was to determine the therapeutic usefulness of a group of predefined trial medicines in benign prostatic hyperplasia. The secondary objective was to check the progression of disease by evaluating changes in prostate volume (PV), post-void residual urine (PVRU) and peak urine flow rates (Qmax and Qavg in ml/sec). Methods:In a multi-centric observational study, 231 patients suffering from benign prostatic hyperplasia (BPH) having prostate volume > 20 mL and prostate specific antigen (PSA) ≤ 4 ng/mL were enrolled at 5 Institutes/Units under Central Council for Research in Homeopathy (CCRH). Symptoms were analyzed using the American Urological …

An Evidence Based Case Study Of Benign Prostatic Hyperplasia, Girish Gupta, Santosh Singh

Indian Journal of Research in Homoeopathy

Benign prostatic hyperplasia (BPH) has been the most frequent reason for elderly men undergoing surgery. BPH symptoms range from least voiding difficulties to urinary retention and renal failure. In this case of BPH, subjective measures such as changes in International Prostatic Symptom Score / American Urological Association Assessment (IPSS/AUA), and objective measures such as changes in prostate size and urinary flow rate were assessed, as the successful management and treatment of BPH should seek both to improve symptoms and prevent disease progression. The case was treated with Lycopodium, a homoeopathic medicine reported here. This case shows the efficacy of medicine …

Ccrh Quarterly Bulletin (1979-81), V Singh

Indian Journal of Research in Homoeopathy

No abstract provided.

Optimizing Network Connectivity For Mobile Health Technologies In Sub-Saharan Africa, Mark J. Siedner, Alexander J. Lankowski, Derrick Musinga, Jonathan Jackson, Conrad Muzoora, Peter W. Hunt, Jeffrey N. Martin, David Bangsberg, Jessica E. Haberer

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background: Mobile health (mHealth) technologies hold incredible promise to improve healthcare delivery in resourcelimited settings. Network reliability across large catchment areas can be a major challenge. We performed an analysis of network failure frequency as part of a study of real-time adherence monitoring in rural Uganda. We hypothesized that the addition of short messaging service (SMS+GPRS) to the standard cellular network modality (GPRS) would reduce network disruptions and improve transmission of data.

Methods: Participants were enrolled in a study of real-time adherence monitoring in southwest Uganda. In June 2011, we began using Wisepill devices that transmit data each time the …

Cross-Cultural Comparison Of Sensory Behaviors In Children With Autism., Kristina G Caron, Roseann C Schaaf, Teal W. Benevides, Eynat Gal

Department of Occupational Therapy Faculty Papers

Parents of children with autism frequently report that their children exhibit unusual responses to sensory experiences. Little research is available, however, describing how parents' and children's culture and environment might influence parents' reports of their children's behaviors. This study compared the frequency of parent-reported responses to sensory experiences in children from two countries-Israel and the United States. We administered the Short Sensory Profile to primary caregivers of children with autism spectrum disorders (ASD) and typically developing peers. Results indicate that Israeli parents reported unusual responses to sensory experiences less frequently than U.S. parents for both ASD and typically developing children. …

Editorial, R Manchanda

Indian Journal of Research in Homoeopathy

No abstract provided.

Homeopathy Emerging As Nanomedicine, Rajendra Upadhyay, Chaturbhuja Nayak

Indian Journal of Research in Homoeopathy

Background:Homeopathy is a time-tested two-century old empirical system of healing. Homeopathic medicines are prepared through a characteristic process known as potentization, where serial dilutions are performed with strong strokes at each step of dilution. Homeopathy is controversial because most medicines do not contain one single molecule of the corresponding starting-substance. Aim:To investigate a possible nanoscience mechanism of action of homeopathic medicines. Methodology: Ultra-pure samples were prepared and were examined under scanning (SEM) and transmission electron microscope (TEM) along with selected area nanodiffraction (SAD) and energy-dispersive X-ray analysis (EDX). Also trace element analysis (TEA) for silicon was performed. Results:Homeopathic medicines showed …

Disease Monograph — Urolithiasis, Seema Rai

Indian Journal of Research in Homoeopathy

No abstract provided.

Dermatofibroma: A Curious Tumor., Lawrence Parish, Shideh Yazdanian, W Clark Lambert, Peter C Lambert

Department of Dermatology and Cutaneous Biology Faculty Papers

A tumor, such as a dermatofibroma, causes consternation among many patients, but it rarely creates problems on its own. Also called a histiocytoma, it remains one of the most common mesenchymal growths. Its etiology is unknown with the previous theory that it is a dermal response to injury, such as an insect bite, being challenged. As much as patients like to blame spiders or other arthropods for traumatizing an arm or leg, no definitive explanation is available for its etiology.

Parvalbumin In Fish Skin-Derived Gelatin: Is There A Risk For Fish Allergic Consumers?, S. J. Koppelman, Julie A. Nordlee, P.-W. Lee, R. P. Happe, M. Hessing, R. Norland, T. Manning, R. Deschene, G. A. H. De Jong, Steve L. Taylor

Department of Food Science and Technology: Faculty Publications

The major allergen parvalbumin was purified from cod muscle tissues, and polyclonal antibodies were raised toward it. The antibodies were tested for specificity, and an enzyme-linked immunosorbent assay (ELISA) was developed using these antibodies. The ELISA was applied to measure parvalbumin in cod skin, the starting material for fish gelatin made from deep sea, wild fish. The ELISA was sufficiently sensitive (LLOQ = 0.8 ng ml^–1 in extracts, corresponding to 0.02 μg of parvalbumin per g of tissue) and did not cross-react with common food constituents. Fish gelatin, wine, and beer, matrices for the potential use of this ELISA, …

Increased Susceptibility To Metabolic Syndrome In Adult Offspring Of Angiotensin Type 1 Receptor Autoantibody-Positive Rats., Suli Zhang, Xi Zhang, Lihong Yang, Zi Yan, Li Yan, Jue Tian, Xiaoyu Li, Li Song, Li Wang, Xiaoli Yang, Ronghua Zheng, Wayne Bond Lau, Xinliang Ma, Huirong Liu

Department of Emergency Medicine Faculty Papers

Abstract Aims: Abnormal fetal and early postnatal growth is closely associated with adult-onset metabolic syndrome (MetS). However, the underlying etiological factors remain complex. The presence of the autoantibody against the angiotensin II type 1 receptor (AT1-Ab), a known risk factor for pre-eclampsia, may create a suboptimal intrauterine fetal environment. The current study investigated whether middle-aged offspring of AT1-Ab-positive mothers were prone to metabolic disorder development. Results: The AT1-Abs was detected in placental trophoblastic cells, capillary endothelium, and milk of pregnant rats actively immunized with the second extracellular loop of the AT1 receptor. AT1-Abs in newborn rats induced vasoconstriction, increased intracellular-free …

Faculty Mentoring: Priceless (Letter To The Editor), Donald D. Miller

College of Nursing Faculty Research and Publications

No abstract provided.

Mexican American Female Adolescents’ Perceptions Of Relationships And Dating Violence, Kristin Haglund, Ruth Ann Belknap, Juanita Terrie Garcia

College of Nursing Faculty Research and Publications

Purpose: This study fills a gap regarding the perspectives of Mexican American female adolescents on dating relationships and dating violence (DV).

Methods: This was a qualitative descriptive study. Focus groups included 20 Mexican American young women, primarily first and second generation, mean age 14.5 years (SD= 2.5). Data were analyzed with categorical analysis.

Findings: Participants described key components of DV and identified cultural aspects that may serve to promote healthy dating relationships.

Conclusions: Family-based interventions to promote exploration of gender roles and parent-child communication may foster biculturalism as well as promote healthy dating relationships and prevent violence within …

Consensus Report By The Institute For Health And Public Justice, Institute For Public Health And Justice, Community Participatory Work, Juvenile Justice System Reform

Policy & Position Papers

No abstract provided.

A Teaching-Learning Initiative With Tablet Computing, Beth Ann Swan, Phd, Crnp, Faan, Kellie Smith, Edd, Rn, Anthony J. Frisby, Phd, Kathryn Shaffer, Msn, Rn, Cne, Mary Hanson-Zalot, Msn, Rn

College of Nursing Faculty Papers & Presentations

Mobile computing and electronic books are the top emerging technologies to impact higher education.¹ The rapid expansion of technology in the health care setting has created a growing recognition that there is a need for adoption of a sound set of innovative teaching-learning strategies related to information management and technology applications in undergraduate nursing curriculum. Success in these technology-related strategies will rest on the degree to which schools comprehensively integrate technology with teaching-learning strategies in the undergraduate nursing curriculum.

Tablet computing has the potential to enhance educational experiences by providing a delivery option for teaching and learning practices that …

A Clinical Prediction Model For Long-Term Functional Outcome After Traumatic Spinal Cord Injury Based On Acute Clinical And Imaging Factors., Jefferson R Wilson, Robert G Grossman, Ralph F Frankowski, Alexander Kiss, Aileen M Davis, Abhaya V Kulkarni, James S Harrop, Bizhan Aarabi, Alexander Vaccaro, Charles H Tator, Marcel Dvorak, Christopher I Shaffrey, Susan Harkema, James D Guest, Michael G Fehlings

Department of Neurosurgery Faculty Papers

To improve clinicians' ability to predict outcome after spinal cord injury (SCI) and to help classify patients within clinical trials, we have created a novel prediction model relating acute clinical and imaging information to functional outcome at 1 year. Data were obtained from two large prospective SCI datasets. Functional independence measure (FIM) motor score at 1 year follow-up was the primary outcome, and functional independence (score ≥ 6 for each FIM motor item) was the secondary outcome. A linear regression model was created with the primary outcome modeled relative to clinical and imaging predictors obtained within 3 days of injury. …

Anxiolytic-Like Effects Of Noni Juice (Morinda Citrifolia L.) On The Respective Changes Of Neurotransmitters In Rat Brain In The Elevated Plus-Maze Test, Sarinee Kalandakanond-Thongsong, Jantarima Charoenphandhu

The Thai Journal of Veterinary Medicine

Noni (Morinda citrifolia L.) has long been used to treat various conditions in folklore medicine. Presently,most studies focus on antioxidant and anti-cancer activities while it is also claimed by noni juice-consumers toproduce happiness. Mood disorders, e.g. anxiety, are symptoms that reflected the disorder of neurotransmitters, oneof the most prominent is the monoaminergic system. Anxiety affects people throughout the world; people have beenseeking medicine for treatment while natural products may also alleviate this unfavorable symptom. The presentstudy examined whether noni contained anxiolytic-like effect when tested with elevated plus-maze (EPM), a standardtest for anxiety, and whether this effect was related to change …

Detection Of Enzootic Bovine Leukosis In Cattle Using Nested Polymerase Chain Reaction Assay, Jomelson Alfaro Uera, Jonathan Ventura Lazaro, Claro Niegos Mingala

The Thai Journal of Veterinary Medicine

Enzootic bovine leukosis (EBL) is caused by bovine leukemia virus (BLV) infection. BLV was detected incattle using nested polymerase chain reaction (PCR) assay and were identified BLV infected cattle farms in fiveselected provinces in the Philippines. A total of 300 cattle blood samples were used. BLV Proviral DNA wasextracted and amplified using nested PCR assay targeting the BLV long terminal repeat (LTR). Results showed that11 samples (3.67%) of the 300 cattle blood samples used were positive for BLV infection. This study is considered firstreport of cattle EBL in the Philippines.

Surgical Treatment Of Renal Gout In Monocellate Cobra, Naja Kaouthia, Taksa Vasaruchapong, Lawan Chanhome

The Thai Journal of Veterinary Medicine

A wild captured, male Monocellate cobra, Naja kaouthia of unknown age was observed with anorexia, imbalance of swimming and mild swelling in the distal fourth of the body. Physical examination revealed a palpable firm mass in the coelomic cavity, of which radiographic examination was suspicious as an obstruction of large intestine by a foreign body. Removal of the foreign body through its cloaca was attempted by enema and digital manipulation, but was not successful. Thereafter, an exploratory surgery was performed and revealed an abnormality in the left kidney that was compressing the large intestine. Nephrectomy was performed and histopathologically identified …

Effectiveness Of A Peer-Led Hiv Prevention Intervention In Secondary Schools In Rwanda: Results From A Non-Randomized Controlled Trial, Kristien Michielsen, Roxanne Beauclair, Wim Delva, Kristien Roelens, Ronan Van Rossem, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

Background: While the HIV epidemic is levelling off in sub-Saharan Africa, it remains at an unacceptably high level. Young people aged 15-24 years remain particularly vulnerable, resulting in a regional HIV prevalence of 1.4% in young men and 3.3% in young women. This study assesses the effectiveness of a peer-led HIV prevention intervention in secondary schools in Rwanda on young people’s sexual behavior, HIV knowledge and attitudes.

Methods: In a non-randomized longitudinal controlled trial, fourteen schools were selected in two neighboring districts in Rwanda Bugesera (intervention) and Rwamagana (control). Students (n= 1950) in eight intervention and six control schools participated …