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Kelly, Rita Helen Roberts (Fa 248), Manuscripts & Folklife Archives

Folklife Archives Finding Aids

KELLY, Rita Helen Roberts 248. Paper: "For a Cold or the Flu, Take..." written by Rita Helen Roberts Kelly for a Western Kentucky University folk studies class.

Working Report On The Status Quo Of Nanomaterials Impact On Health And Environment, Harald Krug, Margarita Apostolova, Marite Arija Bake, Gordon Chambers, Horia Chiriac, Eva Herzog, Victoria Hand, Jürgen Höck, Peter Hoet, Nicoleta Lupu, Declan Mccormack, Maja Remskar, George Robillard, Jamila Smisterova, Jan Stetkiewicz, Speranta Tanasescu, Aris Tsatsakis, David Vaughn, Peter Wick, Jörg Wörle-Knirsch

Articles

Nanotechnology is regarded as one of the key technologies of the future and associated with high expectations by politics, science and economy. Artificially produced nanosized particles and nanoscale system components have new properties which are of importance for the development of new products and applications. Such new properties of materials and substances result from the special properties of surfaces and interfaces and in part, from the geometric shape of the material. In theory nanoparticles (NPs) can be produced from nearly any chemical; however, most NPs that are currently in use today have been made from transition metals, silicon, carbon (single-walled …

Emergence Of Carbapenem Resistant Gram Negative And Vancomycin Resistant Gram Positive Organisms In Bacteremic Isolates Of Febrile Neutropenic Patients: A Descriptive Study., Seema Irfan, Faiza Idrees, Vikram Mehraj, Faizah Habib, Salman Adil, Rumina Hasan

Department of Pathology and Laboratory Medicine

Background:This study was conducted to evaluate drug resistance amongst bacteremic isolates of febrile neutropenic Patients with particular emphasis on emergence of carbapenem resistant Gram negative bacteria and vancomycin resistant Enterococcus species.

Methods:

A descriptive study was performed by reviewing the blood culture reports from febrile neutropenic Patients during the two study periods i.e., 1999-00 and 2001-06. Blood cultures were performed using BACTEC 9240 automated system. Isolates were identified and antibiotic sensitivities were done using standard microbiological procedures.

Results:

Seven twenty six febrile neutropenic Patients were admitted during the study period. A total of 5840 blood cultures were received, off …

Fluorescence Tomography Characterization For Sub-Surface Imaging With Protoporphyrin Ix, Dax Kepshire, Scott C. Davis, Hamid Dehghani, Keith D. Paulsen, Brian W. Pogue

Dartmouth Scholarship

Optical imaging of fluorescent objects embedded in a tissue simulating medium was characterized using non-contact based approaches to fluorescence remittance imaging (FRI) and sub-surface fluorescence diffuse optical tomography (FDOT). Using Protoporphyrin IX as a fluorescent agent, experiments were performed on tissue phantoms comprised of typical in-vivo tumor to normal tissue contrast ratios, ranging from 3.5:1 up to 10:1. It was found that tomographic imaging was able to recover interior inclusions with high contrast relative to the background; however, simple planar fluorescence imaging provided a superior contrast to noise ratio. Overall, FRI performed optimally when the object was located on or …

Public Health Professional Organizational Data, F. Douglas Scutchfield Md

Preventive Medicine and Environmental Health Presentations

No abstract provided.

Clinical Features And Management Of Autoimmune Hepatitis, Edward L. Krawitt

Dartmouth Scholarship

Autoimmune hepatitis (AIH) is a chronic hepatitis of unknown etiology which can progress to cirrhosis. Its clinical manifestations are highly variable and sometimes follow a fluctuating course. Diagnosis is based on characteristic histologic, clinical, biochemical and serological findings. Anti-inflammatory/immunosuppressive treatment frequently induces remission but long-term maintenance therapy is often required. Liver transplantation is generally successful in patients with decompensated cirrhosis unresponsive to or intolerant of medical therapy.

The Role Of Extracellular Matrix And Matrix-Degrading Proteases In Neonatal Hypoxic-Ischemic Injury, Christopher C. Leonardo

USF Tampa Graduate Theses and Dissertations

Improvements in medical care over recent decades have increased the number of premature and low birth weight infants that survive hypoxic-ischemic (H-I) insults. Because there is a rising incidence in diseases associated with these events, it is critical to develop effective therapies to treat the various resulting neuropathies. Extracellular matrix constitutes the majority of brain parenchyma. Lecticans and matrix-degrading proteases including ADAMTSs (a disintegrin and metalloproteinase with thrombospondin repeats) and matrix metalloproteinases (MMPs) exert effects on cell viability and may be associated with either protective or destructive processes after H-I. Both ADAMTSs (Cross et al. 2006; Tian et al. 2007) …

Structural And Functional Mapping Of The Archaeal Multi-Aminoacyl-Trna Synthetase Complex, Corinne D. Hausmann, Michael Ibba

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Methanothermobacter thermautotrophicus contains a multi-aminoacyl-tRNA synthetase complex (MSC) of LysRS, LeuRS and ProRS. Elongation factor (EF) 1A also associates to the MSC, with LeuRS possibly acting as a core protein. Analysis of the MSC revealed that LysRS and ProRS specifically interact with the idiosyncratic N- and C- termini of LeuRS, respectively. EF-1A instead interacts with the inserted CP1 proofreading domain, consistent with models for post-transfer editing by class I synthetases such as LeuRS. Together with previous genetic data, these findings show that LeuRS plays a central role in mediating interactions within the archaeal MSC by acting as a core scaffolding …

The Development Of Word Recognition Materials For Native Speakers Of Tongan, Lara Cahoon Seaver

Theses and Dissertations

The purpose of this study was to develop, digitally record, evaluate, and psychometrically equate a set of Tongan bisyllabic word lists for use in measurement of word recognition testing. Commonly used bisyllabic words were digitally recorded by male and female native talkers of Tongan. The psychometric performance of the words was measured at ten intensity levels (- 5 to 40 dB HL) in 5 dB increments by 20 listeners with normal hearing acuity. The 200 words with the highest rate of listener identification were included in four relatively psychometrically equivalent word lists of 50 words each and eight half-lists of …

Heart Rate Variability Characteristics In Sedentary Postmenopausal Women Following Six Months Of Exercise Training: The Drew Study, Conrad P. Earnest, Carl J. Lavie, Steven N. Blair, Timothy S. Church

Faculty Publications

Background: Decreased heart rate variability (HRV) is associated with a higher risk of mortality. Overall, postmenopausal women have lower levels of HRV than premenopausal women, which may be additionally complicated by lifestyle related behaviors such as physical inactivity and obesity. Though cardiorespiratory exercise training increases HRV, little is known regarding the exercise dose necessary to promote improvement.

Methodology/Principle Findings: Our primary aim was to measure HRV in post-menopausal women following 6-moths of exercise training. We examined supine resting HRV in 373 post-menopausal women (45-75 y) after 6-months of randomly assigned and double-blinded administered exercise training exercise training at 50%, 100% …

Ada News - 06/02/2008, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Spatiotemporal Postural Control Deficits Are Present In Those With Chronic Ankle Instability, Patrick O. Mckeon, Jay Hertel

Physical Therapy Faculty Publications

BACKGROUND: Postural control deficits have been purported to be a potential contributing factor in chronic ankle instability (CAI). Summary forceplate measures such as center of pressure velocity and area have not consistently detected postural control deficits associated with CAI. A novel measurement technique derived from the dynamical systems theory of motor control known as Time-to-boundary (TTB) has shown promise in detecting deficits in postural control related to chronic ankle instability (CAI). In a previous study, TTB deficits were detected in a sample of females with CAI. The purpose of this study was to examine postural control in sample of males …

Enhancing Autonomy In Paid Surrogacy, Jennifer Damelio '06, Kelly Sorensen

Philosophy and Religious Studies Faculty Publications

The gestational surrogate – and her economic and educational vulnerability in particular – is the focus of many of the most persistent worries about paid surrogacy. Those who employ her, and those who broker and organize her services, usually have an advantage over her in resources and information. That asymmetry exposes her to the possibility of exploitation and abuse. Accordingly, some argue for banning paid surrogacy. Others defend legal permission on grounds of surrogate autonomy, but often retain concerns about the surrogate. In response to the dilemma of a ban versus bald permission, we propose a ‘soft law’ approach: states …

Subcutaneous Late Phase Responses Are Augmented During Local Inhalational Tolerance In A Murine Asthma Model, Anurag Singh, Roger S. Thrall, Linda A. Guernsey, William F. Carson Iv, Eric R. Secor Jr, Robert E. Cone, Thiruchandurai V. Rajan, Craig M. Schramm

UCHC Articles - Research

Acute exposure of sensitized mice to antigen elicits allergic airway disease (AAD) characterized by Th2 cytokine-dependent pulmonary eosinophilia, methacholine hyperresponsiveness and antigen-specific IgE elevation. However, chronic exposure induces a local inhalational tolerance (LIT), with resolution of the airway responses but persistent systemic IgE production. To further determine if systemic immunologic responses were maintained during LIT, we assessed subcutaneous late phase responses to ovalbumin in this model. Sensitized and AAD mice developed small subcutaneous responses to ovalbumin, with footpad thickness increasing to 113.7 and 113.6% of baseline, respectively. In comparison, LIT mice developed marked foot swelling (141.6%). Histologic examination confirmed increased …

Molecular Biology: Power Sequencing, Brenton R. Graveley

UCHC Articles - Research

Advances in DNA-sequencing technology provide unprecedented insight into the entire collection of four genomes' transcribed sequences; they herald a new era in the study of gene regulation and genome function.

Separation And Characterization Of Respirable Amphibole Fibers From Libby, Montana, James S. Webber, David J. Blake, Tony Ward, Jean C. Pfau

Public and Community Health Sciences Faculty Publications

The vermiculite mine in Libby, Montana, was in operation for over 70 yr and was contaminated with asbestos-like amphibole fibers. The mining, processing, and shipping of this vermiculite led to significant fiber inhalation exposure throughout the community, and residents of Libby have developed numerous pulmonary diseases such as lung cancer and mesothelioma. The present study describes the separation of Libby 6-mix into respirable and nonrespirable size fractions by means of aqueous elutriation. The elutriator, designed to separate fibers with aerodynamic diameters smaller than 2.5 μm (respirable) from larger fibers, used an upward flow rate of 3.4 × 10^{−4 …}

Original Research Hormonal Response To Carbohydrate Supplementation At Rest And After Resistance Exercise, Sean R. Schumm, N. Travis Triplett, Jeffrey M. Mcbride, Charles Dumke

Integrative Physiology and Athletic Training Faculty Publications

This investigation examined the anabolic-hormone response to carbohydrate (CHO) supplementation at rest and after resistance exercise. Nine recreationally trained men randomly underwent 4 testing conditions: rest with placebo (RPL), rest with CHO (RCHO), resistance exercise with placebo (EPL), and resistance exercise with CHO (ECHO). The resistance-exercise protocol was four sets of Smith machine squats with a 10-repetition-maximum load, with 90-s rests between sets. Participants then consumed either a placebo or CHO (24% CHO, 1.5 g/kg) drink. Blood was taken before exercise (Pre), immediately after testing (Post), and then 15 (15P), 30 (30P), and 60 (60P) min after drink ingestion. Blood …

Reducing Heavy Drinking In Intercollegiate Athletes: Evaluation Of A Web-Based Personalized Feedback Program, Diana Doumas, Tonya Haustveit

Counselor Education Faculty Publications and Presentations

This study evaluated the efficacy of a Web-based personalized feedback program aimed at reducing drinking in freshman intercollegiate athletes. The program was offered through the Athletic Department freshman seminar at a NCAA Division I university. Seminar sections were randomly assigned to one of two conditions: Web-based personalized feedback (WPF) or Web-based education (WE). Assessment measures were completed at baseline, 6 weeks, and 3 months. Athletes were classified as high-risk or low-risk drinkers based on baseline reports of binge drinking. Results indicated for high-risk athletes, students in the WPF condition reported significantly greater reductions in drinking and changes in beliefs about …

Contact Point, Arthur A. Dugoni School Of Dentistry

Contact Point

No abstract provided.

The Evolution Of Language And Perception Of Disability In Occupational Therapy, Kathryn M. Loukas

Occupational Therapy Faculty Publications

How do occupational therapy practitioners refer to the persons they serve, and how do these terms reflect our perception of disability as a profession? In the hospital or medical model, we call these persons patients; in the community we referred to them as clients; in the marketplace, they may be called consumers. Children serviced through the schools often are called students, and persons in long-term care may be called residents. However, most of the individuals we serve carry a diagnostic label that makes them eligible for services and defines the work of therapy (Centers for Disease Control and Prevention [CDC], …

Effects Of Acute Ethyl Alcohol Consumption On A Psychophysical Measure Of Lateral Inhibition In Human Vision., Kevin D Johnston, Brian Timney

Brain and Mind Institute Researchers' Publications

Acute consumption of ethyl alcohol affects a variety of visual functions. However, there have been few systematic attempts to investigate the neural mechanisms underlying these effects. Here, we employed the Westheimer paradigm to investigate the hypothesis that alcohol reduces lateral inhibition within human "perceptive fields", the psychophysical analogue of physiological receptive fields. Westheimer functions obtained under alcohol and no-alcohol conditions at photopic, mesopic, and scotopic levels of adaptation showed changes consistent with an alcohol-induced decrease in lateral inhibition. We conclude that this decrease in lateral inhibition may be responsible for some of the changes in visual perception that result from …

Waiting For Liver Transplantation In Canada: Waitlist History 2000--2004 And Sensitivity Analysis For The Future., David Stanford, Elizabeth Renouf, Vivian Mcalister

Data and Test Instruments

This study comprises a historical review of liver transplants performed in Canada during 2000--2004, and sensitivity analyses to assess the impact of possible changes in the operation of the waitlists. In the first part, overall statistics are reported, and the notable impact that blood type plays in affecting waiting time is discussed. Waiting times and numbers of transplants are also reported by gender, age, and geographic region (waitlist), and statistical analyses of the patient placement and cadaveric donations processes are performed. These analyses establish that the service times of an appropriate queuing model are closely approximated by an exponential distribution. …

Relative Timing Of Speech Motor Events At Utterance Invitation In Persons Who Do And Do Not Stutter, Bryan Thomas Brown

Masters Theses

Speech production is a highly complex speech motor activity that presumably requires a high degree of coordination between articulatory, respiratory and phonatory subsystems. Stuttering may be caused by breakdowns in speech motor coordination. The current study attempted to evaluate timing relationship between these systems at speech initiation in the perceptually fluent speech of people who do and do not stutter. To study this, tongue blade speed histories, respiratory transitions from inspiratory to expiratory gestures, and acoustic events at the initiation of perceptually fluent speech in persons who stutter and normally fluent speakers were analyzed in relative time. To identify the …

What's Happening: Spring, 2008, Maine Medical Center

What's Happening

No abstract provided.

Unmasking Pain: A Look At The Latest Research, Daniel G. Drury, Karen Y. Wonders

Health Sciences Faculty Publications

Recent research into the physical and psychological mechanisms of pain in revealing new ways to help ease the hurt without the use of medication.

Essential Novice Nurse Educator Role Competencies And Qualifications To Teach Ina Pre-Licensure Registered Nurse Education Program, Kathleen A. Poindexter

Dissertations

Expert nurse clinicians who are transitioning into academic positions after successful clinical careers often find they are unprepared to assume their new educator roles. While nursing clinical expertise may be a necessary expectation, the knowledge is not sufficient to assume a nurse educator position. Novice nurse educators prepared with the essential qualifications and competencies associated with the specialty role of a nurse educator will be better able to transition into their new academic roles. This study identified essential entry-level nurse educators' competencies and qualifications as reported by nursing administrators of accredited pre-licensure nursing programs across the United States.

This study …

Spinal Cord Stimulation For Control Of Pain, Stephen Falowski Md

JHN Journal

Spinal cord stimulation (SCS) is an adjustable, non-destructive procedure which delivers therapeutic doses of electrical current to the spinal cord for the management of neuropathic pain. The most common indications include post-laminectomy (“failed back surgery”) syndrome, complex regional pain syndrome (CRPS), ischemic limb pain, and angina. Other reported applications include visceral/abdominal pain, cervical neuritis pain, spinal cord injury pain, post-herpetic neuralgia, and neurogenic thoracic outlet syndrome.

Nerve Growth Factor Regulation Of Cyclin D1 In Pc12 Cells Through A P21ras Extracellular Signal-Regulated Kinase Pathway Requires Cooperative Interactions Between Sp1 And Nuclear Factor-Kappab., Francesco Marampon, Mathew C Casimiro, Maofu Fu, Michael J Powell, Vladimir M Popov, Jaime Lindsay, Bianca M Zani, Carmela Ciccarelli, Genichi Watanabe, Richard J Lee, Richard G Pestell

Department of Cancer Biology Faculty Papers

The PC12 pheochromocytoma cell line responds to nerve growth factor (NGF) by exiting from the cell cycle and differentiating to induce extending neurites. Cyclin D1 is an important regulator of G1/S phase cell cycle progression, and it is known to play a role in myocyte differentiation in cultured cells. Herein, NGF induced cyclin D1 promoter, mRNA, and protein expression via the p21(RAS) pathway. Antisense- or small interfering RNA to cyclin D1 abolished NGF-mediated neurite outgrowth, demonstrating the essential role of cyclin D1 in NGF-mediated differentiation. Expression vectors encoding mutants of the Ras/mitogen-activated protein kinase pathway, and chemical inhibitors, demonstrated NGF …

Drug Overdose: A Wake Up Call! Experience At A Tertiary Care Centre In Karachi, Pakistan, Muhammad Junaid Patel, Muhammad Shahid, Mehmood Riaz, Waqaruddin Kashif, Syed Imran Ayaz, Muhammad Shoaib Khan, A. Jawwad Samdani, Ayesha L Sorathia, Muhammad Furqan

Department of Emergency Medicine

OBJECTIVE: To study the characteristics of patients admitted with drug overdose caused either by accidental overdose of the prescribed medications or as an act of deliberate self harm (DSH) at a tertiary care hospital in Karachi, Pakistan.METHODS: A retrospective case series review was conducted at the Aga Khan University Hospital from January 2002 to October 2006. Three hundred and twenty four adult patients admitted with drug overdose were included in the study.RESULTS: Our sample group revealed mean age of 36.2 +/- 17.0 years, more females (59%), housewives (34%), and students (20%). Fifty six percent of patients committing DSH were married …

Syncope: Experience At A Tertiary Care Hospital In Karachi, Pakistan., Muhammad Junaid Patel, Nadeem Ullah Khan, Abdul Jawwad Samdani, Muhammad Furqan, Aamir Hameed, Muhammad Sohaib, Syed Imran Ayaz, Muhammad Omer Jamil

Department of Emergency Medicine

Introduction:Our aim was to determine the characteristics of Patients presenting with syncope at a tertiary care hospital in Karachi, Pakistan.
Methods: A review of medical records was conducted retrospectively at the Department of Medicine, Aga Khan University Hospital, Karachi. Patients aged 16 and above, admitted from January 2000 to December 2005 with the diagnosis of syncope made by the attending physician were included.
Results:A total of 269 Patients were included (75% males, mean age: 57.4 years). Neurogenic (vasovagal) syncope was the most common cause (47%), followed by cardiogenic syncope (18%) and orthostatic syncope (9%). A total of 24% …