Pharmacology Commons^™

Cytotoxicity And Inhibitory Activity On Hepatitis B Surface Antigen Secretion From Plc/Prf/5 Cells Of Medicinal Plant Extracts, Thaveechai Prommetta, Sattaporn Sirotamarat, Kruavon Balachandra, Ekarin Saifah

The Thai Journal of Pharmaceutical Sciences

Ethanolic extracts of three medicinal plants including Derris scandens, Rhinacanthus nasutus and Santalum album were investb'ated for cytotoxicity by MTT assay and inhibition of hepatitis B surface antigen secretion from PLC/PRF/5 cells by ELISA. Results...

Aqueous Extract Of The Calyces Of Hibiscus Subdariffa Linn.: Effects On Hepatic Cytochrome P450 And Subacute Toxicity In Rats, Promphorn Wirotesangthong, Laddawal Phivthong-Ngam, Chaiyo Chaichantipyuth, Nuansri Niwattisaiwong, Somsong Lawanprasert

The Thai Journal of Pharmaceutical Sciences

Hibiscus sabdariffa Linn, has been reported to have a broad range of therapeutic effects. Subacute effects of the calyces of H. sabdariffa aqueous extract on the activities of cytochrome P450 (CYP), clinical blood chemistry and hematology were investigat...

Antioxidant Activity, Phenolic Compound Contents And Antimutagenic Activity Of Some Water Extract Of Herbs, Kalyarat Mekaroonreung, Kaew Kangsadalampai

The Thai Journal of Pharmaceutical Sciences

Ten water extracts from herbs were prepared by boiling in hot water for 10 min. The herbal extracts were studied for their antioxidant activity and phenolic compound contents. In this study, the extracts of C arthamus tinctorius L, Hibiscus sabdariffa L,...

Effects Of Cassava On Thyroid Gland In Rats, Rubporn N/A

The Thai Journal of Pharmaceutical Sciences

The root of cassava has been consumed as a food in many tropical countries. In pharmaceutical industry, cassava starch can be used as a binder in tablet formulation. Since cassava contains high concentration of linamarin, a cyanogenic glucoside which can...

Detection Of Mycoplasma Contamination In Cell Cultures: Comparison Between Dna Flurorochrom Staining And Pcr Amplification Methods(การตรวจหาการปนเปีอนของเชื้อมัยโคพลาสมาในเ..., Supaporn Phumiamorn, Kornnika Kullabutr, Sukanlayanee Tepbhuthorn, Teeranart Jivapaisarnpong

The Thai Journal of Pharmaceutical Sciences

Mycoplasma contamination of cell cultures is one of the major problems In cell culture technology. Therefore, prevention by continuous surveillance dem ands adequate mycoplasm as testing procedures. In this study, the standard procedures of microbiologic...

Author Index, Key Word Index, N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.

Comparison Of Weight Reduction And Satisfaction Of Orlistat And Sibutramine, Somchai Anansiriwattana, Titinun Auamnoy, Pagorn Taweechotepatr

The Thai Journal of Pharmaceutical Sciences

The study was to compare and evaluate the efficacy and satisfaction of orlistat and sibutramine in Thai overweight females at Adisorn Fort Hospital, Saraburi Province, Thailand. Orlistat is a drug which increases the fecal fat excretion, with gastrointes...

Development Of Single Nanoparticle Optical Assays For Imaging Single Living Cells, William John Brownlow

Chemistry & Biochemistry Theses & Dissertations

Multi-drug resistance (MDR) has been reported in both prokaryotes and eukaryotes; the pathogenic gram-negative bacteria Pseudomonas aeruginosa can extrude a variety of structurally and functionally diverse substrates via a number of membrane transport systems leading to MDR. We have developed a novel nanoparticle assay to characterize both the membrane transport system composed of the MexAB-OprM efflux pump and the membrane permeability induced by antibiotics. Gold (Au) and silver (Ag) nanoparticles were investigated for use as probes to explore membrane transport in P. aeruginosa.

The surface plasmon absorption (color) of Au nanoparticle solutions was found to change in the presence …

Chemical Constitutents And Cytotoxicity Of Some Tanzanian Wild Mushrooms, V. Nyigo, L. D. Baraza, M. H. H. Nkunya, S. J. M. Mdachi, C. C. Joseph, A. Waziri

Tanzania Journal of Science

The sterol ergosterol and ergosta-4,22-diene-3β,7α-diol, together with 4-hydroxybenzaldehyde were isolated from the mushroom species Polyporus molluscensis, Cantharellus isabelinus, C. symoensii and a Podaxis species. Their structures were established on the basis of spectroscopic data. The ethanol extracts of mushroom samples of Agaricus sp. and Termitomyces letestui also showed cytotoxicity against the brine shrimp larvae.

The Effects Of An Analgesic (Biofreeze®) On The Motoneuron Pool Excitability Of The Soleus Muscle, Desiree R. Barth

All-Inclusive List of Electronic Theses and Dissertations

Objective: The purpose of this study was to determine the effects on the Hoffman reflex and motor response with an analgesic (Biofreeze®). Design: The study was a 2X6 design. The independent variables in this study were treatment and time. The dependent variables were the H-reflex (volts) and the M response (volts). Treatment was randomly assigned to control for the effects of order. Setting: This study took place in the Exercise Physiology Laboratory located in the Health and Human Performance Building at Indiana State University. Subjects: 14 volunteers who were physically active and had no known neurological problems. Measurements: Skin and …

Prenatal Cocaine Exposure And Cardiac Programming, Soochan Bae

Loma Linda University Electronic Theses, Dissertations & Projects

Human epidemiological studies have shown a clear association of adverse intrauterine environment and an increased risk of ischemia heart disease in later adult life. Cocaine abuse during pregnancy has been shown to cause abnormities in the heart during fetal and postnatal development, but mechanisms underlying the detrimental effects of cocaine on the developing heart are not fully understood. The central hypothesis is that cocaine exposure during fetal development may cause in utero programming of apoptotic pathways, which may has lasting and prolong effect on heart development postnatally.

In a pregnant rat model, chronic hypoxia increased apoptosis in the fetal heart …

Receptor Mediated Oral Delivery Of Bioencapsulated Green Fluorescent Protein Expressed In Transgenic Chloroplasts, Arati Limaye

Electronic Theses and Dissertations

The skyrocketing costs of prescription medicine in developed countries and their lack of availability in developing countries are the most challenging problems of human health. Primary reasons for such high cost are fermentation-based production, expensive purification methods, the need for low temperature storage and transportation and the delivery through sterile injections. Most of these expenses could be minimized or eliminated when therapeutic proteins are expressed and orally delivered via plant cells. Chloroplasts have the machinery to fold complex and biologically active eukaryotic proteins in the soluble chloroplast stromal compartment. Protein expression through chloroplast transformation system offers a number of advantages …

Discovery Shook Medical, Pharmaceutical Industries, Aldemaro Romero Jr., David Gilmore

Publications and Research

No abstract provided.

Preparation Of Fast Release Indomethacin Solid Dispersion By Spray- Drying Using Lactose As Water-Soluble Carrier(การเตรียมอินโดเมธาชินโซลิดดิสเพอร์ชันชนิดปลดปล..., Pienkit Dangprasirt, Vasinee Limwong

The Thai Journal of Pharmaceutical Sciences

Solid dispersions of a poorly water-soluble drug, indomethacin (ID), in a water-soluble carrier, lactose, were prepared by coprecipitation method using a spray dryer. Dissolution tests were performed on the prepared ID and 1-2 IDdactose solid dispersion ...

Access To Medicinal Plant Resources In Vietnam - A Fair And Equitable Sharing Of Benefits(การเข้าถึงทรัพยากรพืชสมุนไพรในเวียดนาม-การนำไปใช้ประโยช..., Tran Cong Khanh

The Thai Journal of Pharmaceutical Sciences

Abstract There are in Vietnam 3,830 registered medicinal plant species, apart from numerous ethno- medicinal plants which have not been sufficiently inventoried and documented. Traditional knowledge in using animals and plants for treatment and health ca...

Anti-Heroes Simplex Virus Type 1 Activity Of Local Northeastern Plants(ฤทธิ์ต้าน Herpes Simplex Virus Type 1 ของพืชผักท้องถิ่นในภาคอีสาน), Pannarat Akanitapichat, Aree Wangmaneerat, Nongnit Teerawatanasuk

The Thai Journal of Pharmaceutical Sciences

Eighty extracts sequentially percolated from forty local northeastern plants with dichloromethane- methanol (DCM'M, 1:1) and methanol were evaluated for in vitro anti-herpes simplex virus type 1 (HSV-1) activity. Using plaque reduction assay, 31 extracts...

Evaluation Of Anticonvulsant Activity Of Valproyl Hydroxamic Acid(การประเมินฤทธิ์ต้านชักของกรดวาลโปรอิลไฮดรอกซามิก), Boonyong Tantisira, Mayuree H., Chamnan Patarapanich, Nalinrat Thongsathean

The Thai Journal of Pharmaceutical Sciences

Valproyl hydroxamic acid (VHA) is a novel derivative of valpromide, a pro-drug of valproic acid (VPA). Preliminary screening of VHA revealed its anticonvulsant activity against electrically induced convulsion in mice. Additional evaluation of its efficac...

แก้ไข, N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.

Skin Permeation Enhancement Of Ketoprofen Supersaturated Solutions With Antinucleant Polymers(การเพิ่มการซึมผ่านผิวหนังของสารละลายอิ่มตัวยิ่งยวดของ..., Tanasait Ngawhirunpat, Praneet Opanasopit, Suwannee Panomsuk, Theerasak Rojanarata, Usanee Kumprakrob

The Thai Journal of Pharmaceutical Sciences

Skin permeation enhancement of ketoprofen (KP) from supersaturated systems and effects of three antinucleant polymers, polyvinylpyrrolidone (PVP), hydroxypropylmethylcellulose (HPMC) and sodium carboxymethylcellulose (SCMC), on stability and skin permeat...

Antimutagenicity Of 4-Hexylresorcinol Against Urethane In Somatic Mutation And Recombination Test(ผลของการต้านฤทธิ์ก่อกลายพันธุ์ของ 4-เฮ็กซิลรีซอร์ซินอล..., Kaew Kangsadalampai, Suphaphan Soiphet

The Thai Journal of Pharmaceutical Sciences

This study examined the effect of 50, 500 and 5000 ppm of 4-hexylresorcinol (4-HR) on the mutagenicity of 2500 ppm urethane (URE) through somatic mutation and recombination testing using a high bioactivation cross of Drosophila melanogaster as the indica...

Effects Of Monascus Colorants On The Mutagenicity Of Nitrite-Treated 1-Aminopyrene Using Ames Test(ผล ของส ีท ี่ได ้จ าก เชื้อ รา Monascus ต่อฤทธก,อ ก ล ายพ ัน ธ ุข อ ง..., Kalyarat Kruawan, Kaew Kangsadalampai, Busaba Yongsmith, Thayat Sriyapai

The Thai Journal of Pharmaceutical Sciences

We studied the antimutagenicity of natural colorants synthesized by Monascus purpureus (ATCC 16365, NRRL 2897) and unidentified Monascus sp. (KB13.1, KB10M16 and KB20M10.2) against the reaction product (nitrite-treated 1-aminopyrene) produced from the re...

Properties Testing Of The Retranslated Sf-36 (Thai Version)(การทดสอบคุณสมบัติของแบบสอบถาม Sf-36 ภาษาไทยฉบับแปลใหม่), Watcharee Leurmarnkul, Paranee Meetam

The Thai Journal of Pharmaceutical Sciences

Quality of life assessment is an outcome measurement that has been increasingly focused by clinicians. At present, SF-36 (Thai version) is a widely used instrument. We previously reported validation results of the SF-36 which was proved unsatisfactory on...

Evaluation Of Piroxicam Gel Formulations: Comparison Between In Vitro Permeation, In Vivo Pharmacological And Skin Stripping Techniques(การประเมินสูตรตำรับไพรอกซิแคมเจล : การเปร..., Parkpoom Tengamnuay, Witthaya Janthasoot, Maytinee Limsiriwong

The Thai Journal of Pharmaceutical Sciences

Purpose. To evaluate the topical bioavailability and efficacy of various piroxicam gel products using in vitro permeation, in vivo pharmacological and skin stripping techniques and to compare these methods for possible correlation. Methods. Four commerci...

Key Word Index, Author Index(ดรรชนีกุญแจคำ, ดรรชนีผู้แต่ง), N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.

Development And Testing Of Thai Smoking Cessation Pharmaceutical Therapy-Related Quality Of Life Assessment Instrument(การสร้างและทดสอบเครื่องมือประเมินคุณภาพชีวิตจ..., Supakit Wongwiwatthananukit, Rawadee Dhumma-Upakorn, Thitipom Naktuan

The Thai Journal of Pharmaceutical Sciences

The purpose of this methodological research was to develop a smoking cessation pharmaceutical therapy-related quality of life assessment instrument and examine the validity and reliability of this measure. This research involves 3 steps: (1) instrument d...

Comparison Of The Management Between Independent And Chain Drugstores In Municipal Area, Muang District, Chiang Mai Province(การเปรียบเทียบการบริหารจัดการร้านขายยา ระหว..., Chupen Viboonsunti, Poobate Keawpinta, Montree Sornbial, Eakarin Chadchuchaitip

The Thai Journal of Pharmaceutical Sciences

The objective of this study was to compare the management of independent drugstores and chain drugstores in municipal area, Muang District, Chiang Mai Province. Interviews of thirty drugstores consisting twenty independent drugstores and ten chain drugst...

Discrepancies Of Patient Package Inserts Of 24 Brand Name Oral Contraceptive Pill Products In Thailand(ความไม่สอดคล้องกันของเอกสารกำกับยาสำหรับผู้ใช้ยารั..., Sumamas Rabeab-Oat, Supawadee Petch-Phrom, Jurapom Pongwecharak

The Thai Journal of Pharmaceutical Sciences

The study was to examine and compare drug information provided in package inserts of oral contraceptive products marketed in Thailand. List of the products currently marketed in Thailand was obtained from Drug Control Division, Food and Drug Administrati...

Antiviral And Anticancer Activities Of Stemona Collinsae(ฤทธิ์ต้านไวรัส และฤทธิ์ต้านมะเร็งของ Stemona Collinsae), Pannarat Akanitapichat, Pajaree Tongngok, Aree Wangmaneerat, Bungom Sripanidkulchai

The Thai Journal of Pharmaceutical Sciences

The roots of Stemona (Stemonaceae) have long been used traditionally for the treatment of respiratory diseases, enteric helminthes and as insecticides. In the present study, the dichloromethane-methanol (DCM-M, :1), 95% ethanol and aqueous extracts of St...

Terpenoid Constituents From Leaves And Cell Cultures Of Artemisia Vulgaris Var. Indica And Application Of Biotechnological Techniques To Increase Davanone Level(สารกลุ่มเทอร์ปินอยด์จากใบและเซล..., Supawan Bunrathep, Thanapat Songsak, Nijsiri Ruangrungsi

The Thai Journal of Pharmaceutical Sciences

Sterilised leaf expiants of Artemisia vulgaris var. indica were placed on semisolid basal MS media, containing 1 mg/1 of 2 ,4 -dichlorophenoxyacetic acid and 0.1 mg/1 of kinetin in order to initiate callus cultures. Cell suspension cultures were then ini...

Dna Fingerprinting Of Medicinally Used Derris Species By Rapd Molecular Markers(ลายพิมพ์ดีเอ็นเอของพืชสมุนไพรสกุล Derris โดยใช้เครื่องหมายโมเลก..., Suchada Sukrong, Thatree Phadungcharoen, Nijsiri Ruangrungsi

The Thai Journal of Pharmaceutical Sciences

DNA fingerprinting of five medicinal used Derris species, D. scandens, D. elliptica, D. malaccensis, D. trifoliata, and D. reticulata, was studied using random amplified polymorphic DNA (RAPD) technique. In medicinal plant market, herbal drugs were often...