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Full-Text Articles in Pharmacology

Identification And Characterization Of Possible Multiple Binding Sites For ((3)H)8-Oh-Dpat In The Hippocampus, Dawna Lea Evans Dec 1992

Identification And Characterization Of Possible Multiple Binding Sites For ((3)H)8-Oh-Dpat In The Hippocampus, Dawna Lea Evans

Masters Theses

No abstract provided.


Fixed-Ratio Size As A Determinant Of The Development Of Tolerance To Morphine, Mark J. Nickel Aug 1992

Fixed-Ratio Size As A Determinant Of The Development Of Tolerance To Morphine, Mark J. Nickel

Masters Theses

The acute and chronic effects of morphine were examined in pigeons exposed to a multiple schedule with fixed ratio 5, 25, and 125 components. Acute exposure to morphine (0.56-10.0 mg/kg) resulted in rate reductions under each component when the dose was 1 mg/kg or higher. With chronic exposure to 5.6 mg/kg, tolerance to the rate-reducing effects of morphine was evident under each fixed ratio component. The development of tolerance was determined to some extent by fixed-ratio size, a result similar to earlier findings with cocaine.


Pesticide Safe Use Unit, Palarp Sinhaseni Jan 1992

Pesticide Safe Use Unit, Palarp Sinhaseni

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Role Of The Vascular Endothelium In The Responsiveness Of Isolated Procine Coronary And Renal Artery To Some Vasoactive Neurotransmitters.(บทบาทของเยื่อบุหลอดเลือดต่อการออกฤทธิ์..., Aurachorn Inkanuwat, Prasan Dhumma-Upakorn, Supatra Srichairat Jan 1992

Role Of The Vascular Endothelium In The Responsiveness Of Isolated Procine Coronary And Renal Artery To Some Vasoactive Neurotransmitters.(บทบาทของเยื่อบุหลอดเลือดต่อการออกฤทธิ์..., Aurachorn Inkanuwat, Prasan Dhumma-Upakorn, Supatra Srichairat

The Thai Journal of Pharmaceutical Sciences

A comparative study of effect of Acetylcholine (ACH) and Noradrenaline (NA ) to the responsiveness of isolated porcine left anterior descending coronary and renal artery were investigated. ACh ( 1x10 -6 M) markedly induced contraction in the coronary art...


The Effect Of Gambogic Acid On Gastrointestinal Smooth Muscle(ฤทธิ์ทางเภสัชวิทยาของแกมโบจิกแอซิดจากรงทองต่อกล้ามเนื้อเรียบหางเ..., Chandhanee Itthipanichpong, Prasan Dhumma-Upakorn, Nijsiri Ruangrungsi, Pinnarat Pengkoom Jan 1992

The Effect Of Gambogic Acid On Gastrointestinal Smooth Muscle(ฤทธิ์ทางเภสัชวิทยาของแกมโบจิกแอซิดจากรงทองต่อกล้ามเนื้อเรียบหางเ..., Chandhanee Itthipanichpong, Prasan Dhumma-Upakorn, Nijsiri Ruangrungsi, Pinnarat Pengkoom

The Thai Journal of Pharmaceutical Sciences

Gambogic acid is a pure compound isolated from gamboge (Rongthong), a gum-resin extruded from Garcinia hanburyi Hookf. The pharmacological effects of this compound have been investigated in isolated rabbit, rat and mice organ preparations and conscious m...


Central Serotonergic Stimulation Of Renin Secretion, Peter Andrew Rittenhouse Jan 1992

Central Serotonergic Stimulation Of Renin Secretion, Peter Andrew Rittenhouse

Dissertations

No abstract provided.


Effect Of 2-Methoxy-L, 4-Naphthoquinone On Mitochondrial Respiration.(ผลของ 2-เมท็อกซี่-1, 4-แนพโทดวิโนน ที่มีต่อกระบวนการหายใจ ของไมโดคอน..., Yupadee Vanichayachart, Withaya Janthasoot, Monthol Sanguansermsrp Jan 1992

Effect Of 2-Methoxy-L, 4-Naphthoquinone On Mitochondrial Respiration.(ผลของ 2-เมท็อกซี่-1, 4-แนพโทดวิโนน ที่มีต่อกระบวนการหายใจ ของไมโดคอน..., Yupadee Vanichayachart, Withaya Janthasoot, Monthol Sanguansermsrp

The Thai Journal of Pharmaceutical Sciences

2-methoxy-l, 4-naphthoquinone (MNQ), the compound that extract from the leaf of Garden Balsam (Impatiens balsamina), was found to stimulate state 4 respiration of isolated rat liver mitochondria. This compound showed difference in mechanism of action fro...


Development Process Of Pra-Sa-Ma-Wang Anticough And Expectorant Drug(กระบวนการผลิตยาเม็ดแกไอ ขับเสมหะ สูตรพัฒนาจากยาประสะมะแว้ง), Malee Bunjob Jan 1992

Development Process Of Pra-Sa-Ma-Wang Anticough And Expectorant Drug(กระบวนการผลิตยาเม็ดแกไอ ขับเสมหะ สูตรพัฒนาจากยาประสะมะแว้ง), Malee Bunjob

The Thai Journal of Pharmaceutical Sciences

Tablet formula of Pra-sa-ma-wang, a Thai official traditional household remedy was developed by using modern medicine standards. The powder of Pra-sa-ma-wang per tablet was decreased to 50 from 200 milligrams in the traditional formula. Five excepients :...


เส้นทางสู่เภสัชกรรมคลีนิคในโรงพยาบาล Stepped Approach To Clinical Pharmacy, นิตยา คณาวงษ์ Jan 1992

เส้นทางสู่เภสัชกรรมคลีนิคในโรงพยาบาล Stepped Approach To Clinical Pharmacy, นิตยา คณาวงษ์

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Variation Of Active Constituents Of Curcuma Domestica Rhizomes At Different Ages(การเปลี่ยนแปลงปริมาณสารสำคัญของขมิ้นชัน ในระยะเวลาเก็บเกี่..., Pranee Chavalittumrong, Warunee Jirawattanapong Jan 1992

Variation Of Active Constituents Of Curcuma Domestica Rhizomes At Different Ages(การเปลี่ยนแปลงปริมาณสารสำคัญของขมิ้นชัน ในระยะเวลาเก็บเกี่..., Pranee Chavalittumrong, Warunee Jirawattanapong

The Thai Journal of Pharmaceutical Sciences

Rhizomes of Curcuma domestica Valeton at different ages were collected from Nakorn Pathom and Prachuap Khiri Khan provinces. The quantities of the active constituents, curcuminoids and volotile oil, of the rhizomes were determined. It was found that rhiz...


Inhibitory Effects Of Some 8-Prenylflavones Isolated From Tephrosia Apollinea On Platelet Aggregation (ผลของการยับยั้งการจับตัวของเกล็ดเลือดของ 8- พรีนีลฟลา..., Osama B. Abdel-Halim, Fumio Ikegami, Ahmed F., Hosny Abdel-Fattah, Jiro Arita, Yuichi Fujii, Toshikazu Sekine, Isamu Murakoshi Jan 1992

Inhibitory Effects Of Some 8-Prenylflavones Isolated From Tephrosia Apollinea On Platelet Aggregation (ผลของการยับยั้งการจับตัวของเกล็ดเลือดของ 8- พรีนีลฟลา..., Osama B. Abdel-Halim, Fumio Ikegami, Ahmed F., Hosny Abdel-Fattah, Jiro Arita, Yuichi Fujii, Toshikazu Sekine, Isamu Murakoshi

The Thai Journal of Pharmaceutical Sciences

7-Oxygenated-8-prenylflavones, (-)-semiglabrin (1), (+)-glabratephrin (2), (+)-glabratephrinol (3), (-)- pseudosemiglabrin (4) and (-)-pseudosemiglabrinol (5), were isolated from the aerial parts ofTephrosia apollinea (Leguminosae). Among these compounds...


Jsps-Nrct Core University System, Pharmaceutical Sciences, First Joint Seminar, Advance In Research On Pharmacologically Active Substances From Natural Sources, N/A Jan 1992

Jsps-Nrct Core University System, Pharmaceutical Sciences, First Joint Seminar, Advance In Research On Pharmacologically Active Substances From Natural Sources, N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Not For Us, But For Our Descendants, Geoffrey A. Cordell Jan 1992

Not For Us, But For Our Descendants, Geoffrey A. Cordell

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Uncoupling Of Mitochondrial Oxidative Phosphorylation By Ancistrotectorine(การอันคัปปลิงของกระบวนการออกสิเดทีฟ ฟอสฟอริลเลซัน ของไมโตคอนเ..., Wiboon Wattanatorn, Nijsiri Ruangrungsi, Withaya Janthasoot Jan 1992

Uncoupling Of Mitochondrial Oxidative Phosphorylation By Ancistrotectorine(การอันคัปปลิงของกระบวนการออกสิเดทีฟ ฟอสฟอริลเลซัน ของไมโตคอนเ..., Wiboon Wattanatorn, Nijsiri Ruangrungsi, Withaya Janthasoot

The Thai Journal of Pharmaceutical Sciences

Ancistrotectorine, a new alkaloid from Ancistrocladus tectorius, was found to possess uncoupling activity on isolated rat liver mitochondria. This compound stimulated state 4 respiration and consequently reduced respiratory control index and ADP/O ratio ...


Iron And Folic Acid Contents In Traditonal Haematinic Drugs And Ha Em All Nic Herbs(ปริมาณธาตุเหล็กและกรดโฟลิกในยาบำรุงเลือดแผนใบราณ และสมุนไ..., Oranong Kangsadalampai, Suteera Selta-Apitarn Jan 1992

Iron And Folic Acid Contents In Traditonal Haematinic Drugs And Ha Em All Nic Herbs(ปริมาณธาตุเหล็กและกรดโฟลิกในยาบำรุงเลือดแผนใบราณ และสมุนไ..., Oranong Kangsadalampai, Suteera Selta-Apitarn

The Thai Journal of Pharmaceutical Sciences

Thai women used traditional haematinic drugs for a long time. However, there were no scientific evidence to show that these drugs contain sufficient essential nutrients, iron and folic acid, for red blood cell formation in human. The present study was co...


Formulation Of Dermatological Preparations From Extract Of Impatiens Balsamina Leaves.(การพัฒนาตำรับยาบำบัดโรคผิวหนังจากสารสกัดใบเทียนบ้าน), Pranom Pothiyanont, Suchada Prasertvithyakarn, Waraporn Suwakul, Saree Virunhapol, Areerat Laorpaksa, Thatree Phadungcharoen, Ekarin Saifah Jan 1992

Formulation Of Dermatological Preparations From Extract Of Impatiens Balsamina Leaves.(การพัฒนาตำรับยาบำบัดโรคผิวหนังจากสารสกัดใบเทียนบ้าน), Pranom Pothiyanont, Suchada Prasertvithyakarn, Waraporn Suwakul, Saree Virunhapol, Areerat Laorpaksa, Thatree Phadungcharoen, Ekarin Saifah

The Thai Journal of Pharmaceutical Sciences

2-Methoxy-l, 4-naphthoquinone, isolated from Impatiens balsamina leaves, was quite stable in oleaginous base, absorption base and water soluble base. In o/w type emulsion base, it could be stabilized with 0.01% citric acid. The 0.5% concentration of the ...


An Amino Add Derivative From The Leaves Of Aglaia Pyramidata Hance, Ekarin Saifah, Jindaporn Puripattanavong Jan 1992

An Amino Add Derivative From The Leaves Of Aglaia Pyramidata Hance, Ekarin Saifah, Jindaporn Puripattanavong

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


A Biscoumarin From The Seeds Of Linostoma Pauciflomm, Khanit Suwanborirux, Noppamas Suppakun, Hiroshi Noguchi, Ushio Sankawa Jan 1992

A Biscoumarin From The Seeds Of Linostoma Pauciflomm, Khanit Suwanborirux, Noppamas Suppakun, Hiroshi Noguchi, Ushio Sankawa

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Synthesis Of Monoureide Analogues Of Valproic Acid(การสังเคราะห์โมโนยูรีดแอนนะลอกของวัลโปรอิก แอชิด), Boonardt Saisorn, Chamnan Patarapanich, Wicharn Janwitayanuchit Jan 1992

Synthesis Of Monoureide Analogues Of Valproic Acid(การสังเคราะห์โมโนยูรีดแอนนะลอกของวัลโปรอิก แอชิด), Boonardt Saisorn, Chamnan Patarapanich, Wicharn Janwitayanuchit

The Thai Journal of Pharmaceutical Sciences

Two monoureide analogues of valproic acid were synthesized. N(2-propylpentanoyl) urea was synthesized by acylating urea with valproyl chloride. N(2-propylpentanoyl) thiourea was synthesized via the valproylisothio cyanate intermediate and concentrated am...


Study On Pepper Oil Content And Composition Of Sri Lankan And Sarawak Cultivars Grown In Thailand(การศึกษาหาปริมาณและองค์ประกอบของน้ำมันหอมระเหย ในพริ..., Waraporn Putalun, Wanchai De-Eknamkul Jan 1992

Study On Pepper Oil Content And Composition Of Sri Lankan And Sarawak Cultivars Grown In Thailand(การศึกษาหาปริมาณและองค์ประกอบของน้ำมันหอมระเหย ในพริ..., Waraporn Putalun, Wanchai De-Eknamkul

The Thai Journal of Pharmaceutical Sciences

Black pepper has long been a major exported spice of Thailand. It is normally obtained from two cultivars, the Sarawak and Sri Lankan, which are grown locally in Thailand. Comparison between the quality of the black pepper of these two different sources ...


Computer Program For Analysis Of Drug Release Kinetics And Mechanisms Of Sustained Release Products(โปรแกรมคอมพิวเตอร์สำหรับการวิเคราะห์หาจลนศาสตร์และ ก..., Phuriwat Leesawat, Poj Kulvanich Jan 1992

Computer Program For Analysis Of Drug Release Kinetics And Mechanisms Of Sustained Release Products(โปรแกรมคอมพิวเตอร์สำหรับการวิเคราะห์หาจลนศาสตร์และ ก..., Phuriwat Leesawat, Poj Kulvanich

The Thai Journal of Pharmaceutical Sciences

The computer program in Macro language of Lotus 123 for analysis of the drug release data obtained from the in vitro dissolution studies of sustained release products is reported. On the basis of linear regresion analysis, the program determines the corr...


Absolute Configuration Of L-Methionine Sulfoximine As A Toxic Principle In Cnestis Palala (Lour.) Merr., Isamu Murakoshi, Toshikazu Sekine, Kiyomi Maeshima, Fumio Ikegami, Koichiro Yoshinaga, Yuichi Fujii, Siriporn Okonogi Jan 1992

Absolute Configuration Of L-Methionine Sulfoximine As A Toxic Principle In Cnestis Palala (Lour.) Merr., Isamu Murakoshi, Toshikazu Sekine, Kiyomi Maeshima, Fumio Ikegami, Koichiro Yoshinaga, Yuichi Fujii, Siriporn Okonogi

The Thai Journal of Pharmaceutical Sciences

An unusual amino acid, L-methionine sulfoximine (1), has been isolated from the fresh seeds of Cnestis palala (Lour.) Merr. (Connaraceae). The absolute configuration of the natural sulfoximine (1) was confirmed to be shown as 2(S)-methionine S(S)-sulfoxi...


Implementation Of Gmp : A Challenging Match, Caroline De Bruijn Jan 1992

Implementation Of Gmp : A Challenging Match, Caroline De Bruijn

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Biosynthesis Of Heterocyclic Β-Substituted Alanines In Higher Plants, Fumio Ikegami, Isamu Murakoshi Jan 1992

Biosynthesis Of Heterocyclic Β-Substituted Alanines In Higher Plants, Fumio Ikegami, Isamu Murakoshi

The Thai Journal of Pharmaceutical Sciences

Naturally occurring heterocyclic β-substituted alanines such as L-quisqualic acid and β-(pyrazol-l-yl) -Lalanine are enzymatically synthesizedfrom O-acetyl-L-serine and suitable precursors by cysteine synthases in the same manner as the formation of L-...


Simultaneous Determination Of Individual Curcuminoids In Turmeric By Tlc-Densitometric Method(การวิเคราะห์หาปริมาณเคอร์คูมินอยด์แต่ละชนิด ในเหง้าขมิ..., Supinya Tewtrakul, Wanchai De-Eknamkul, Nijsiri Ruangrungsi Jan 1992

Simultaneous Determination Of Individual Curcuminoids In Turmeric By Tlc-Densitometric Method(การวิเคราะห์หาปริมาณเคอร์คูมินอยด์แต่ละชนิด ในเหง้าขมิ..., Supinya Tewtrakul, Wanchai De-Eknamkul, Nijsiri Ruangrungsi

The Thai Journal of Pharmaceutical Sciences

A simple, rapid and accurate method of TLC-densitometry was developed to quantitate simultaneously the three curcuminoid components in the dried turmeric rhizome of Curcuma longa L. (Zingiberaceae). Practically, the curcuminoids in powdered turmeric were...


Enzymic Methylation Of Lawsone To Form 2-Methoxy-1,4-Naphthoquinone In Impatiens Bals Amin A Leaves, Pharkphoom Panichayupakaranant, Wanchai De-Eknamkul Jan 1992

Enzymic Methylation Of Lawsone To Form 2-Methoxy-1,4-Naphthoquinone In Impatiens Bals Amin A Leaves, Pharkphoom Panichayupakaranant, Wanchai De-Eknamkul

The Thai Journal of Pharmaceutical Sciences

A novel methyltransferase enzyme which catalyzes the méthylation of lawsone to form 2-methoxy-1,4- naphthoquinone has been discovered from the leaves of Impatiens balsamina L.


Hepatoprotective Effect Of Andrographis Paniculata And Andrographolide Against Carbontetrachloride(ผลของฟ้าทะลายโจรและแอนโตรกราฟโฟไลด์ ในการปกป้องตับจา..., Pornpimol Kijsanayotin, Chaiyo Chaichantipayuth Jan 1992

Hepatoprotective Effect Of Andrographis Paniculata And Andrographolide Against Carbontetrachloride(ผลของฟ้าทะลายโจรและแอนโตรกราฟโฟไลด์ ในการปกป้องตับจา..., Pornpimol Kijsanayotin, Chaiyo Chaichantipayuth

The Thai Journal of Pharmaceutical Sciences

Hepatoprotective efficacy of A. paniculata and its major diterpenoid lactone, andrographolide, was studied in CCl4 -induced hepatotoxicity in rats comparing with glycyrrhizin. A single oral administration of dried leaf pow der of A. paniculata (1,000 mg/...


Pharmaceutical Technology Of Starch: Invention Of Directly Compressible Starch(เทคโนโลยีเภสัชกรรมของแป้ง : แป้งดัดแปลงสำหรับใช้ในการตอกยาเม..., Siriyos Timaroon, Poj Kulvanich Jan 1992

Pharmaceutical Technology Of Starch: Invention Of Directly Compressible Starch(เทคโนโลยีเภสัชกรรมของแป้ง : แป้งดัดแปลงสำหรับใช้ในการตอกยาเม..., Siriyos Timaroon, Poj Kulvanich

The Thai Journal of Pharmaceutical Sciences

Physico-chemical modification of various native starches were performed and theirs compressibility were assessed in comparison with other modified starches commercially available. Modified rice starch derived by the process in this study exhibited the hi...


Author Index, Subject Index (ดัชนีผู้แต่ง, ดัชนีคำสำคัญ), N/A Jan 1992

Author Index, Subject Index (ดัชนีผู้แต่ง, ดัชนีคำสำคัญ), N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Coumarins From The Leaves Of Triphasia Trifolia, Nijsiri Ruangrungsi, Gordon L., Michael G. Organ Jan 1992

Coumarins From The Leaves Of Triphasia Trifolia, Nijsiri Ruangrungsi, Gordon L., Michael G. Organ

The Thai Journal of Pharmaceutical Sciences

Examination of the leaves of Triphasia trifolia (Rutaceae ) revealed the presence of seven prenylated coumarins: murrangatin (1). triphasiol (2), byakangelicin (3), mexoticin (4), meranzin hydrate (5). aurapten (6) and heraclenol (7).