Human and Clinical Nutrition Commons^™

The Effects Of Highlighting Healthy Options On Consumer Food Choices In A Food Bank Setting, Kaitlin Nicole Grabow

Theses and Dissertations

Objective: The purpose of this study was to determine the effects of highlighting healthy food options on consumer food choices in a food bank setting.

Methods: Two community food banks participated in this study. One food bank served as the control, while a second food bank was rearranged so that fresh produce and other healthy products were the first options that shoppers encountered upon entering. After shopping, carts were inventoried for healthy vs non-healthy products. Composition of the carts from the control food bank were then compared to the contents of the carts from the intervention food bank.

Results: A …

Fiber Intake In Hemodialysis Patients And Its Effects On Symptoms, Jennifer Langner

Theses and Dissertations

On average 30 million adults are diagnosed with chronic kidney disease (CKD) in the United States (National Kidney Foundation, 2017). Patients in late stage kidney disease and on dialysis are placed on a restrictive diet to aid in the treatment of their disease. There are adverse symptoms associated with dialysis including nausea, constipation, diarrhea and fatigue. Fiber has been shown to decrease gastrointestinal symptoms such as reducing constipation and inflammation in the body in healthy populations. This study examined 19 hemodialysis dialysis patients and their fiber intake in relation to a variety of symptoms such as constipation, nausea, vomiting, diarrhea, …

Hydration Knowledge And Intake In High School Student Athletes, Erin Ortiz

Theses and Dissertations

Objective: Heat related illness is one of the leading causes of death in high school athletes.

Proper hydration strategies have been shown to decrease heat related illness in college and

professional athletes. However, limited research has been conducted on the hydration habits of

high school athletes. The increase in high school sports participation has put more athletes at

risk for dehydration. The purpose of the study is to investigate the hydration status and impact of

an educational intervention on hydration habits of high school student athletes, by assessing their

current understanding of hydration and monitoring their fluid intake, during practice. …

Development And Validation Of The Policies, Opportunities, Initiatives And Notable Topics (Points) Audit For Campuses And Worksites, Tanya M. Horacek, Marlei Simon, Elif Dede Yildirim, Adrienne A. White, Karla P. Shelnutt, Kristin Riggsbee, Melissa D. Olfert, Jesse Morrell, Anne E. Matthews, Wenjun Zhou, Tandalayo Kidd, Kendra Kattelmann, Geoffrey Greene, Lisa Franzen-Castle, Sarah E. Colby, Carol Byrd-Bredbenner, Onikia Brown

Department of Nutrition and Health Sciences: Faculty Publications

Background: Workplace or campus wellness/obesity-prevention policies and initiatives can improve health. Research tools to assess worksite or campus policies/initiatives are scarce. Thus, the aim of this research is to develop and validate the policies, opportunities, initiatives, and notable topics (POINTS) audit. Methods: POINTS was developed and refined via expert review, pilot-testing, and field testing. Trained researchers completed a web-based review from a student-focus or employee-focus regarding 34 health-promoting topics for colleges. Each topic was evaluated on a 0–2 scale: 0 = no policy/initiative, 1 = initiatives, 2 = written policy. When a written policy was detected, additional policy support questions …

Development Of The Icook 4-H Curriculum For Youth And Adults: Cooking, Eating, And Playing Together For Childhood Obesity Prevention, Lisa Franzen-Castle, Sarah E. Colby, Kendra K. Kattelmann, Melissa D. Olfert, Douglas Mathews, Katheryn Yerxa, Barbara Baker, Michelle Krehbiel, Tracy Lehrke, Kimberly Wilson, Amber Ford, Trina Aguirre, Adrienne A. White

Health and Nutritional Sciences Faculty Publications

The objective was to describe the development process of a curriculum (iCook 4-H) targeted to low-income, rural, and/or diverse youths and their adult primary meal preparer to promote cooking, eating, and playing together. Lessons learned highlighted the importance of grounding the curriculum in Social Cognitive Theory and applying the experiential 4-H learning model using a multiphased, community-based participatory approach with cyclical development and evaluation, and key modifications made for dissemination and distribution. Findings across 4 testing phases over 6 years and 5 states demonstrated the time-intensive, cyclical process that required flexibility with fidelity to form a hands-on, interactive curriculum.

Ethiopia’S High Childhood Undernutrition Explained: Analysis Of The Prevalence And Key Correlates Based On Recent Nationally Representative Data, Tafere Gebreegziabher Belay, Nigatu Regassa

All Faculty Scholarship for the College of the Sciences

Objective

To examine the contribution of child, maternal and household factors in stunting, wasting and underweight among children under 5 years in Ethiopia. Design

Quantitative cross-sectional design based on nationally representative data. Setting

Urban and rural areas of Ethiopia. Participants

Younger (0–24 months; n 4199) and older age groups (25–59 months; n 5497), giving a total of 9696 children. Results

Among the younger age group, 29 % were stunted, 14 % were wasted and 19 % were underweight; and among the older age group, the prevalence of stunting, wasting and underweight was 47, 8 and 28 %, respectively. Being female, …

An Iterative Process For Training Design And Implementation Increased Health Workers' Knowledge For Taking Nutrition Behavior Change To Scale, Wendy Gonzalez, Anabelle Bonvecchio Arenas, Armando García-Guerra, Mireya Vilar-Compte, Alejandría Villa De La Vega, Laura Quezada, Cynthia Rosas, Ana Lilia Lozada-Tequeanes, Amira Hernández

Department of Public Health Scholarship and Creative Works

The shortage of skilled, motivated, and well-supported health workers is a major barrier to scaling up nutrition interventions and services. Objective: The objective of this study is to describe the process for developing and implementing a training of health personnel for the delivery of the Integrated Strategy for Attention to Nutrition (EsIAN), an evidence-based strategy for promoting infant and young child feeding through primary health care in Mexico. The specific objective is to provide a case study and highlight challenges, as well as elements to successfully mitigate these, and discuss potential applications of findings beyond the Mexican context. Methods: The …

Dietary Polyphenols And Their Perceived Health Benefits, Stephanie Russell

Honors Program: Senior Projects (Public)

This paper will consist of a compilation of information on polyphenol classes, dietary sources, and potential health benefits. Polyphenols can be classified as flavonoids, phenolic acids, lignans, or stilbenes. These molecules consist of over 500 plant metabolites that come from numerous food sources including various fruits, vegetables, grains, and beverages such as coffee, tea, and wine. The quantity of polyphenols in food vary greatly, as does their bioavailability for use in the body after consumption. Due to antioxidant and anti-inflammatory properties, polyphenols are being studied for effects on reducing the risk of cardiovascular disease. This paper will focus on structural …

Maternal Choline Supplementation Modulates Placental Markers Of Inflammation, Angiogenesis, And Apoptosis In A Mouse Model Of Placental Insufficiency, Julia H. King, Sze Ting (Cecilia) Kwan, Jian Yan, Xinyin Jiang, Vladislav G. Fomin, Samantha P. Levine, Emily Wei, Mark S. Roberson, Marie A. Caudill

Publications and Research

Dlx3 (distal-less homeobox 3) haploinsufficiency in mice has been shown to result in restricted fetal growth and placental defects. We previously showed that maternal choline supplementation (4X versus 1X choline) in the Dlx3+/�� mouse increased fetal and placental growth in mid-gestation. The current study sought to test the hypothesis that prenatal choline would modulate indicators of placenta function and development. Pregnant Dlx3+/�� mice consuming 1X (control), 2X, or 4X choline from conception were sacrificed at embryonic (E) days E10.5, E12.5, E15.5, and E18.5, and placentas and embryos were harvested. Data were analyzed separately for each gestational day controlling for litter …

Development And Validation Of The Vending Evaluation For Nutrient-Density (Vend)Ing Audit., Tanya M Horacek, Elif Dede Yildirim, Melissa Matthews Schreiber, Carol Byrd-Bredbenner, Sarah E. Colby, Adrienne A White, Karla P. Shelnutt, Melissa D. Olfert, Anne E Mathews, Kristin Riggsbee, Lisa Franzen-Castle, Jesse Morrell, Kendra Kattelmann

Health and Nutritional Sciences Faculty Publications

Background: This paper describes the development and validation of the Vending Evaluation for Nutrient-Density (VEND)ingaudit to comprehensively evaluate vended products based upon healthfulness, price and promotion, and machine accessibility. Methods: A novel vending nutrient-density score was created to determine the healthfulness of vended snack/beverage products. Field tested in United States colleges, VENDing audit (∑nutrient-density + 10 × % healthy products) and Support sub-scores (price + promotion + accessibility) were calculated for snack/beverage machines. Higher scores indicate more healthful vending options and supports for choosing healthfully. Nutrition Environment Measures Survey-Vending (NEMS-V) was used to validate the nutrient-density score for a sub-sample …

Cooking Frequency Associated With Dietary Quality In Icook-4h Youth Participants At Baseline, Amber D. Ford, Sarah E. Colby, Marissa Mcelrone, Lisa Franzen-Castle, Melissa D. Olfert, Kendra K. Kattelmann, Adrienne A. White

Department of Nutrition and Health Sciences: Faculty Publications

Background: Increased intakes of ready-made and fast foods paralleled with decreased homemade food consumption have been associated with increased rates of obesity. Researchers have shown associations between cooking self-efficacy (SE) and cooking frequency (CF) with dietary quality and weight status. Some cooking interventions have shown positive associations with dietary outcomes, such as increased fruit and vegetable intake and decreased fast food consumption. There is still much unknown about SE and CF, especially among youth.

Objective: Determine baseline SE and CF and the associations with dietary quality and body mass index (BMI) of youth enrolled in iCook 4H.

Methods: Youth (n …

Micrornas In Bovine Milk Exosomes Are Bioavailable In Humans But Do Not Elicit A Robust Pro-Inflammatory Cytokine Response, Ezra Mutai, Amanda E. Ramer-Tait, Janos Zempleni

Department of Nutrition and Health Sciences: Faculty Publications

Background: Bovine milk exosomes are studied for their roles as bioactive food compounds and as vehicles for drug delivery. Both lines of investigation converge on immune function, e.g., immune regulation by absorption of microRNAs encapsulated in milk exosomes across species boundaries, and the possibility of exosomes and their cargos triggering an immune response if used in drug delivery. This study assessed the bioavailability of immune-related microRNAs from bovine milk and changes in plasma cytokine concentrations after milk consumption in humans, and the secretion of cytokines by human peripheral blood mononuclear cells (PBMCs) cultured with milk exosomes transfected with immune-relevant microRNAs. …

Effects Of Red Raspberry Polyphenols And Metabolites On Biomarkers Of Inflammation And Insulin Resistance In Prediabetes And Type 2 Diabetes, Reynaldo Moreno Ucles

LSU Doctoral Dissertations

Berry fruits are rich sources of polyphenolic compounds (PCs), which can promote health benefits. Anthocyanin concentrations of red raspberry (RR)(Rubus idaeus) extracts were determined to be a total of 887.6 ± 262.8 μg/g cyanidin-3-sophoroside (C3S) equivalents with C3S being the most prevalent. Ellagitannin analysis by MALDI-TOF indicated sanguiin H-6 and lambertianin C were the major ellagitannins present in RR. To explore the efficacy of RR in modulating diabetes, seven type 2 diabetes mellitus (T2DM) and two pre-diabetic patients were given drinks delivering one RR serving (123 g) per day in a smoothie for two weeks. Blood samples were …

Cooking And Meal Planning As Predictors Of Fruit And Vegetable Intake And Bmi In First-Year College Students, Andrea J. Hanson, Kendra K. Kattleman, Lacey A. Mccormack, Wenjun Zhou, Onikia N. Brown, Tanya M. Horacek, Karla P. Shelnutt, Tandalayo Kidd, Audrey Opoku-Acheampong, Lisa D. Franzen-Castle, Melissa D. Olfert, Sarah E. Colby

Faculty & Staff Scholarship

The objective was to determine if cooking skills and meal planning behaviors are associated with greater fruit and vegetable intake and lower body mass index (BMI) in first-year college students who are at risk for excessive weight gain. A cross-sectional analysis was conducted using baseline data from a multi-state research project aimed at preventing weight gain in first-year college students. Cooking type, frequency and confidence, self-instruction for healthful mealtime behavior intention, self-regulation of healthful mealtime behavior, and cup equivalents of fruits and vegetables (FV) were measured using validated surveys. BMI was calculated from measured height and weight. First-year students (n …

Tanglewood Trail Walking And Voucher Program, Kelci Marie Mchugh

Theses and Dissertations--Nutrition and Food Systems

Rural Appalachian populations have greater rates of obesity and chronic diseases attributed to lesser consumption of fruits and vegetables (F/V) and physical inactivity. Barriers to F/V consumption and physical activity include poor access and affordability. To help overcome these barriers, a community-initiated walking and farmers market F/V voucher program was implemented.

Participants were encouraged to walk (1.2 miles roundtrip) to the local farmers market to redeem a $10 voucher which could only be spent on F/V. The 16-week program (June – Sept) included 121 participants. Data was analyzed by creating two groups, low-engagers and high-engagers that differed significantly in the …

State Population Influences Athletic Performance Combine Test Scores In High School-Aged American Football Players, Zachary M. Gillen, Marni E. Shoemaker, Brianna D. Mckay, Joel T. Cramer

Department of Nutrition and Health Sciences: Faculty Publications

This study compared athletic performance differences among high school American football combine participants originating from states of different population sizes. High school-aged American football players (n=7,214) who had participated in athletic performance combines between March 2015 and January 2016 were included in this analysis. Data included combine date and location, school state of origin, football position, class, height, weight, 10-, 20-, and 40-yd dash times, pro-agility, L-cone drill, vertical jump, broad jump, and power push-up. Participants were separated into high- (state population>10,000,000; HIGH; n=2,804), mid- (state population=5,000,000-9,999,999; MID; n=2,911), or low-population (state population<5,000,000; LOW; n=1,499) state of origin. Data were allometrically scaled to account for differences in body mass across high school grade levels and American football positions. All statistical analyses were performed on the allometrically scaled data. LOW athletes performed better than HIGH athletes in the 20-yd dash (p≤0.01). LOW athletes performed better than HIGH and MID in the 40-yd dash, proagility, broad jump, and power push-up (p<0.01). LOW and HIGH athletes performed better than MID in the Lcone and vertical jump (p<0.01). When considering population size, athletes originating from LOW states may demonstrate higher levels of athletic performance in football combine events hypothetically due to more opportunities for sports participation and playing time, leading to greater athletic development. Youth and high school coaches in MID and HIGH states might consider providing more opportunities for playing and individualized coaching to encourage long-term athletic development.

Development And Validation Of The Vending Evaluation For Nutrient-Density (Vend)Ing Audit, Tanya M. Horacek, Elif Dede Yildirim, Melissa Matthews Schreiber, Carol Byrd-Bredbenner, Sarah E. Colby, Adrienne A. White, Karla P. Shelnutt, Melissa D. Olfert, Anne E. Matthews, Kristin Riggsbee, Lisa Franzen-Castle, Jesse Stabile Morrell, Kendra Kattelmann

Department of Nutrition and Health Sciences: Faculty Publications

Background: This paper describes the development and validation of the Vending Evaluation for Nutrient-Density (VEND)ing audit to comprehensively evaluate vended products based upon healthfulness, price and promotion, and machine accessibility. Methods: A novel vending nutrient-density score was created to determine the healthfulness of vended snack/beverage products. Field tested in United States colleges, VENDing audit (Σnutrient-density + 10 x % healthy products) and Support sub-scores (price + promotion + accessibility) were calculated for snack/beverage machines. Higher scores indicate more healthful vending options and supports for choosing healthfully. Nutrition Environment Measures Survey-Vending (NEMS-V) was used to validate the nutrient-density score for a …

Development And Validation Of The Policies, Opportunities, Initiatives And Notable Topics (Points) Audit For Campuses And Worksites, Tanya M. Horacek, Marlei Simon, Elif Dede Yildirim, Adrienne A. White, Karla P. Shelnutt, Kristin Riggsbee, Melissa D. Olfert, Jesse Stabile Morrell, Anne E. Matthews, Wenjun Zhou, Tandalayo Kidd, Kendra Kattelmann, Geoffrey Greene, Lisa Franzen-Castle, Sarah E. Colby, Carol Byrd-Bredbenner, Onikia Brown

Department of Nutrition and Health Sciences: Faculty Publications

Background: Workplace or campus wellness/obesity-prevention policies and initiatives can improve health. Research tools to assess worksite or campus policies/initiatives are scarce. Thus, the aim of this research is to develop and validate the policies, opportunities, initiatives, and notable topics (POINTS) audit. Methods: POINTS was developed and refined via expert review, pilot-testing, and field testing. Trained researchers completed a web-based review from a student-focus or employee-focus regarding 34 health-promoting topics for colleges. Each topic was evaluated on a 0–2 scale: 0 = no policy/initiative, 1 = initiatives, 2 = written policy. When a written policy was detected, additional policy support questions …

The Validity Of The Emg And Mmg Techniques To Examine Muscle Hypertrophy, Ethan C. Hill, Terry J. Housh, Josh L. Keller, Cory M. Smith, Richard Schmidt, Glen O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Objective: The purpose of this investigation was to examine the ability of the electromyographic (EMG) and mechanomyographic (MMG) amplitude versus torque relationships to track group and individual changes in muscle hypertrophy as a result of resistance training.

Approach: Twelve women performed four weeks of forearm flexion blood flow restriction (BFR) resistance training at a frequency of three times per week. The training was performed at an isokinetic velocity of 120°∙s⁻¹ with a training load that corresponded to 30% of concentric peak torque. Muscle hypertrophy was determined using ultrasound-based assessments of muscle cross-sectional area from the biceps …

Urolithin A, A Gut Metabolite, Improves Insulin Sensitivity Through Augmentation Of Mitochondrial Function And Biogenesis, Ashley Mulcahy Toney, Rong Fan, Yibo Xian, Virginia Chaidez, Amanda E. Ramer-Tait, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Objective: Urolithin A (UroA) is a major metabolite of ellagic acid produced following microbial catabolism in the gut. Emerging evidence has suggested that UroA modulates energy metabolism in various cells. However, UroA’s physiological functions related to obesity and insulin resistance remain unclear. Methods: Male mice were intraperitoneally administrated either UroA or dimethyl sulfoxide (vehicle) along with a high-fat diet for 12 weeks. Insulin sensitivity was evaluated via glucose and insulin tolerance tests and acute insulin signaling. The effects of UroA on hepatic triglyceride accumulation, adipocyte size, mitochondrial DNA content, and proinflammatory gene expressions were determined. The impact of UroA on …

Milk-Derived Exosomes And Metabolic Regulation, Janos Zempleni, Sonal Sukreet, Fang Zhou, Di Wu, Ezra Mutai

Department of Nutrition and Health Sciences: Faculty Publications

Exosomes are natural nanoparticles that play an important role in cell-to-cell communication. Communication is achieved through the transfer of cargos, such as microRNAs, from donor to recipient cells and binding of exosomes to cell surface receptors. Exosomes and their cargos are also obtained from dietary sources, such as milk. Exosome and cell glycoproteins are crucial for intestinal uptake. A large fraction of milk exosomes accumulates in the brain, whereas the tissue distribution of microRNA cargos varies among distinct species of microRNA. The fraction of milk exosomes that escapes absorption elicits changes in microbial communities in the gut. Dietary depletion of …

Effects Of Alpha-Gpc And Huperzine-A On Short Term Memory, Anaerobic Power Output, Post Exhaustion Compared To Caffeine And Placebo In Healthy College Age Students, John P. Isaacs

Online Theses and Dissertations

Introduction: The use of multi-ingredient pre-workout supplements has been steadily on the rise in the fitness industries. Companies make claims about improvements in performance both physically and cognitively for users but seldom provide research to back up the claims made about the ingredients or dosages. Purpose: To examine the effects of Huperzine-A and Alpha-GPC on short term memory and anaerobic power output, post exhaustion compared to caffeine and placebo in healthy college age students. Methods: The study was conducted as a double blind, placebo controlled, randomized design on 62 healthy adults (N=62 height 68.4 ± 3.5 in., weight 78.5 ± …

The Effects Of Acute Omega-3 Fatty Acid Supplementation On Delayed-Onset Muscle Soreness And Recovery, Colin A. Butler

College of Graduate Studies: Theses & Dissertations

Delayed-onset muscle soreness (DOMS) is the feeling of discomfort that occurs after being exposed to unaccustomed eccentric resistance training often resulting in diminished athletic performance. Previous research has shown positive effects with omega-3 fatty acid (O3FA) supplementation to ameliorate DOMS. The purpose of this study was to investigate the effects of acute O3FA supplementation on perceived muscle soreness, ratings of exertion, and recovery after a lower body resistance training protocol in college-aged males. A double blind, repeated-measures design was utilized with 10 healthy, college-age males. Participants were placed in the placebo (olive leaf oil) or experimental (O3FA) group, consuming 3,000 …

Perceptions Of Health Coaching And Its Associations With Personality Style And Weight Loss In Meal Replacement Program Participants, Bailey Judith Larson

Electronic Theses and Dissertations

Purpose: To determine if personality style is related to perceptions of health coaching and if there is a relationship between perceptions of health coaching and the ability to lose weight. Methods: Data was gathered from approximately 2,000 MR program participants via an electronic survey. The Client Evaluation of Motivational Interviewing scale was used to determine if perceptions of health coaching affect the ability to lose weight. The Ten Item Personality Inventory was used to determine if personality style is associated with the perception of health coaching. Self-reported start weight and current weight were used to calculate percent of starting weight. …

Differences In Running Mechanics And Tibial Plateau Dimensions Between Overweight/Obese And Healthy Weight Children, Claire Sylvestre

Electronic Theses and Dissertations

INTRODUCTION: Overweight and obese (OW/OB) children display increased knee joint loading during running, which may lead to excessive frontal plane motion and moments at the knee joints. The relationship between tibial plateau dimensions and knee vertical loading may explain the loading related injuries OW/OB children experience.
PURPOSE: Compare knee mechanics during running and tibial plateau dimensions between healthy weight (HW) and OW/OB children.
METHODS: Ten HW children and ten OW/OB children aged 9-12 participated in the study. Kinematic and kinetic data were captured as participants ran across a force platform at 3.5m/s. Tibial plateau area and density were collected by …

The Role Of A Community Coach In Rural Food Councils In Six Midwestern States, Kaitlyn Tusha

Electronic Theses and Dissertations

Objective: To quantitatively assess perceived coaching confidence of a community coach working with food councils, and to qualitatively determine perceived barriers and facilitators associated with coaching rural food councils.
Design: Two phases were implemented using a mixed methods study design with quantitative (scorecard) and qualitative (key informant interviews) methodologies.
Setting: Six rural, Midwestern states implementing Voices for Food.
Participants: Voices for Food community coaches (n=9) who coached rural food council(s).
Intervention: A component of the broader Voices for Food intervention.
Analysis: Quantitative scorecard data were analyzed with STATA by running paired ttests. Qualitative key information interview data were analyzed with …

Relationship Of Weight-Related Eating Behaviors And Weight-Loss Of Participants In A Proprietary Weight-Loss Program, Megan Tschakert

Electronic Theses and Dissertations

The aim of this study is to evaluate weight-related eating behaviors of participants with clinically significant weight loss (CSWL) in a proprietary weight loss program. A crosssectional sample of participants (n=1,454) enrolled in a proprietary weight-loss program that includes meal replacements and health coaching were queried for weight-related eating behaviors (using Weight Related Eating Questionnaire) of routine restraint (RR), compensatory restraint (CR), susceptibility to external cues (SEC), and emotional eating (EE) in relation to CSWL (defined as having achieved a weight loss greater than 10% of starting weight). Participants were dichotomized into those with CSWL (n=973) and with no CSWL …

The Efficacy Of Protein Supplementation On Attenuating Muscle Atrophy Following Disuse In The Collegiate Population, Leah Kroeger

Electronic Theses and Dissertations

The purpose of this study is to determine the effects of a protein supplementation protocol through a period of muscular disuse in maintaining muscle mass, strength, jump force production, and cross-sectional area in the collegiate population. Two groups of healthy collegiate participants underwent two weeks of unilateral lower limb suspension (ULLS), during which the control group consumed a normal diet and the treatment group received an additional 75 g of protein supplementation. Lean mass, strength, and force production were measured between dietary intakes at baseline and following immobilization. Muscle area was lost between both groups following ULLS (treatment, - 282.8 …

Effects Of Weight Loss On Gut Microbiota, Samitinjaya Dhakal

Electronic Theses and Dissertations

Incidence of obesity continues to rise for several decades now. Despite the availability of the multiple weight loss programs, losing or maintaining weight remains a universal challenge. A comprehensive lifestyle modification is usually the cornerstone for achieving weight loss. A wealth of new information on gut microbial responses to diet to impact human health has introduced a new frontier in nutrition science that may help better understand inter-individual response variations to weight-loss interventions. This observational study examined the microbiota changes after weight-loss in relation to age, sex, and body-composition features in adults. A 10% reduction in body weight resulted in …

Diet, Prebiotics And Probiotics: Effects On Gut Microbiota In Obesity And Metabolic Disorders, Thamer Aljutaily

Electronic Theses and Dissertations

Targeting gut microbiota with diet, prebiotics, and probiotics are emerging as a promising intervention in the comprehensive nutritional approach to reducing obesity and metabolic disorders. Recent human and animal studies suggest that such intervention can promote health benefits by influencing the aspects of metabolism and immunity. However, study of the multi-role association between the diet, the host and the microbiota remains to be clarified. My dissertation attempts to clarify the problem of how gut microbiota (taxonomic composition and predicted functional capacities) affects obesity and metabolic disorders.
In chapter 2, I conducted a placebo-controlled intervention clinical trial to evaluate effects of …