Human and Clinical Nutrition Commons^™

Scavenger Receptor B1 Facilitates The Endocytosis Of Escherichia Coli Via Tlr4 Signaling In Mammary Gland Infection, Qamar Taban, Syed Mudasir Ahmad, Peerzada Tajamul Mumtaz, Basharat Bhat, Ehtishamul Haq, Suhail Magray, Sahar Saleem, Nadeem Shabir, Amatul Muhee, Zahid Amin Kashoo, Mahrukh Hameed Zargar6, Abrar A. Malik, Nazir A. Ganai, Riaz A. Shah

Department of Nutrition and Health Sciences: Faculty Publications

SCARB1 belongs to class B of Scavenger receptors (SRs) that are known to be involved in binding and endocytosis of various pathogens. SRs have emerging role in regulating innate immunity and host–pathogen interactions by acting in co-ordination with Toll-like receptors.Query Little is known about the function of SCARB1 in milk-derived mammary epithelial cells (MECs). This study reports the role of SCARB1 in infection and its potential association in TLR4 signaling on bacterial challenge in Goat mammary epithelial cells (GMECs). The novelty in the establishment of MEC culture lies in the method that aims to enhance the viability of the cells …

Gut Microbial Metabolite Indole: A Stimulator Of Enteroendocrine Cell Differentiation Via Activation Of Aryl Hydrocarbon Receptor, James Hart

Theses, Dissertations and Capstones

Enteroendocrine cells (EECs) regulate energy balance and glucose homeostasis by releasing hormones in response to food intake. Dysregulated EEC differentiation is observed in obesity, while gut microbiota metabolites influence this process. Here, we investigated the role of indole, a biologically active gut microbial metabolite, in EEC differentiation through aryl hydrocarbon receptor (AhR) activation. Human intestinal organoids derived from jejunal mucosal biopsies were exposed to indole. Indole treatment significantly increased mRNA levels of chromogranin A, an EEC marker. The effect was reversed by an AhR antagonist, indicating AhR involvement. Indole also upregulated AhR target gene mRNA levels. These findings highlight the …

Site-Specific Incidence Rate Of Blastocystis Hominis And Its Association With Childhood Malnutrition: Findings From A Multi-Country Birth Cohort Study, Barbie Zaman Wahid, Ahshanul Haque, Amran Gazi, Shah Mohammad Fahim, Abu Syed Golam Faruque, Mustafa Mahfuz, Tahmeed Ahmed

Department of Nutrition and Health Sciences: Faculty Publications

In this study, we investigated the potential association between the burden of asymptomatic Blastocystis spp. (Blastocystis hominis) infection and nutritional status among children under 2 years of age using the data collected from 1,715 children from eight distinct geographic locations, including Bangladesh, Brazil, India, Peru, Tanzania, Pakistan, Nepal, and South Africa. Childhood stunting, wasting, and underweight were the outcome variables, and B. hominis infection was the exposure variable of this present study. The presence of B. hominis in nondiarrheal stools was evaluated by TaqMan Array Cards. Site-specific incidence rates were estimated using Poisson regression, and multiple generalized estimating …

A Systematic Review Of Marketing Practices Used In Online Grocery Shopping: Implications For Wic Online Ordering, Leslie Hodges, Caitlin M. Lowery, Priyanka Patel, Joleen Mcinnis, Qi Zhang

Community & Environmental Health Faculty Publications

The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) plans to allow participants to redeem their food package benefits online, i.e., online ordering. As grocery shopping online has become more common, companies have developed strategies to market food products to customers using online (or mobile) grocery shopping platforms. There is a significant knowledge gap in how these strategies may influence WIC participants who choose to shop for WIC foods online. This review examines the relevant literature to (1) identify food marketing strategies used in online grocery shopping platforms, (2) understand how these strategies influence consumer behavior and consumer …

Kidney Stones And Energy Drinks: A Literature Review, Donovan D. Bentz

Schultz-Werth Award Papers

Kidney stones are common, painful, and expensive to treat. Several factors play a role in the development of stones, particularly the consumption of sugars such as fructose. As such, the consumption of sugary energy drinks contributes to the development of kidney stones. However, there is a lack of understanding behind the mechanism of kidney stone development and the role energy drinks play in stone development. This review analyzes the mechanism of kidney stone development and the effect energy drink consumption has on stone development. Here, we also detail the dietary roles calcium, oxalate, ascorbic acid, and animal protein have on …

The Relationship Between Alpha-Defensin 1 And Gut Microbiome Composition In A Population Of Bhutanese Refugee Adults With A High Prevalence Of Type 2 Diabetes, Daisha Alana Drake

Honors Theses and Capstones

The New Hampshire Bhutanese refugee population is disproportionately affected by obesity and metabolic disorders such as type 2 diabetes. The gut microbiome is important for overall human health, with high microbial richness and diversity being associated with reduced chronic inflammation and type 2 diabetes risk. Microbial richness and diversity have been shown to decrease in United States (U.S.) immigrant populations, but have not been measured in refugee populations. One of the anti-inflammatory functions of the gut microbiome is related to the production of short-chain fatty acids (SCFAs), which regulate pro-inflammatory cytokine production. Alpha-defensin 1 is an antimicrobial peptide that is …

Risk Of Low Energy Availability, Disordered Eating, And Menstrual Dysfunction In Female Collegiate Runners, Leah Louise Dambacher

All Master's Theses

Collegiate female distance runners may be at risk for low energy availability (LEA) due to increased exercise energy expenditure with or without decreased energy intake. Furthermore, this population has increased risk of disordered eating (DE), which can lead to LEA and negative health consequences, such as menstrual dysfunction (MD). Purpose: The purpose of this study was to: 1) investigate risk of LEA and DE and 2) compare DE, training volume, and weight dissatisfaction among female collegiate runners athletes at risk vs not at risk for LEA. Methods: Female runners (n = 287) who competed on an NCAA Division …

Obesity During Adolescence And Feeding Practices During Infancy: Cross-Sectional Study, Reem Sharaf-Alddin, Radhia Almathkoori, Hara Kostakis, Ahmed N. Albatineh, Abdullah Al-Taiar, Muge Akpinar-Elci

Community & Environmental Health Faculty Publications

Background: Breastfeeding is proposed to play a role in reducing the risk of obesity throughout life. Kuwait has an extremely high prevalence of childhood obesity (45% of adolescents are overweight/obese) and extremely low breastfeeding indicators, particularly exclusive breastfeeding. In fact, little is known about the association between breastfeeding and obesity from Kuwait and the broader Middle East.

Aims: To estimate the prevalence of overweight/obesity in female adolescents in Kuwait and assess its association with breastfeeding during infancy.

Methods: This is a cross-sectional study that included 775 girls randomly selected from public and private high schools in Kuwait. The primary exposure …

Site-Specific Analysis Of The Incidence Rate Of Enterotoxigenic Escherichia Coli Infection Elucidates An Association With Childhood Stunting, Wasting, And Being Underweight: A Secondary Analysis Of The Mal-Ed Birth Cohort, Ahshanul Haque, Sabiha Nasrin, Parag Palit, Rina Das, Barbie Zaman Wahid, Amran Gazi, Mustafa Mahfuz, Abu Syed Golam Faruque, Tahmeed Ahmed

Department of Nutrition and Health Sciences: Faculty Publications

Asymptomatic infection by fecal enteropathogens is a major contributor to childhood malnutrition. Here, we investigated the incidence rate of asymptomatic infection by enterotoxigenic Escherichia coli (ETEC) and assessed its association with childhood stunting, wasting, and being underweight among children under 2 years of age. The Malnutrition and Enteric Disease birth cohort study included 1,715 children who were followed from birth to 24 months of age from eight distinct geographic locations including Bangladesh, Brazil, India, Peru, Tanzania, Pakistan, Nepal, and South Africa. The TaqMan array card assay was used to determine the presence of ETEC in the nondiarrheal stool samples collected …

The Paradox Of Child Poverty And Welfare, Tirna Purkait

Department of Nutrition and Health Sciences: Faculty Publications

The United States confronts persistent child welfare issues rooted in poverty. The age-old debate vacillates between advocating personal responsibility and bolstering social safety nets. Current welfare programs, aiming to mitigate child poverty, often fall short given the deep nexus of poverty and child maltreatment. This paper probes the intricate ties between child poverty and welfare, emphasizing state legislative variances, inherent system paradoxes, and potential policy enhancements. Exploring historical contexts, existing societal frameworks, and future reforms, this research emphasizes the urgency for all-encompassing solutions. These should tackle poverty’s core while fortifying child welfare, safeguarding the well-being of forthcoming American generations.

Examining Neighborhood-Level Hot And Cold Spots Of Food Insecurity In Relation To Social Vulnerability In Houston, Texas, Ryan Ramphul, Linda Highfield, Shreela Sharma

Faculty, Staff and Student Publications

Food insecurity is prevalent and associated with poor health outcomes, but little is known about its geographical nature. The aim of this study is to utilize geospatial modeling of individual-level food insecurity screening data ascertained in health care settings to test for neighborhood hot and cold spots of food insecurity in a large metropolitan area, and then compare these hot spot neighborhoods to cold spot neighborhoods in terms of the CDC's Social Vulnerability Index. In this cross-sectional secondary data analysis, we geocoded the home addresses of 6,749 unique participants screened for food insecurity at health care locations participating in CMS's …

Role Of Human Gut Microbiota In Shaping The Diet-Induced Metabolome, Samitinjaya Dhakal

Electronic Theses and Dissertations

No abstract provided.

Nutrient Intakes, Compliance With Recommendations And Key Sources In Women Of Child-Bearing Age (18-50 Y) In Ireland, Abigail O' Mahony

Theses

Women’s pre-conceptional health (including nutritional status) is important for both the health of the individual themselves and also for the lifelong health of any occurring offspring. However, it has been estimated that up to 50% of pregnancies are unplanned, thus optimal nutritional status is important for all women of child-bearing age (WCBA) not just those with pregnancy intentions. Despite the accumulation of evidence of the importance of nutritional status at this life-stage, nutrient recommendations for WCBA for the most part don’t differ from recommendations for other population groups. The notable exception to this is that all WCBA are recommended to …

Novel Therapeutic Nutrients Molecules That Protect Against Zika Virus Infection With A Special Note On Palmitoleate, Philma Glora Muthuraj, Chandan Krishnamoorthy, Ann Anderson-Berry, Corrine K. Hanson, Sathish Kumar Natarajan

Department of Nutrition and Health Sciences: Faculty Publications

Zika virus (ZIKV) is a Flavivirus from the Flaviviridae family and a positive-sense single strand RNA virus. ZIKV infection can cause a mild infection to the mother but can be vertically transmitted to the developing fetus, causing congenital anomalies. The prevalence of ZIKV infections was relatively insignificant with sporadic outbreaks in the Asian and African continents until 2006. However, recent epidemic in the Caribbean showed significant increased incidence of Congenital Zika Syndrome. ZIKV infection results in placental pathology which plays a crucial role in disease transmission from mother to fetus. Currently, there is no Food and Drug Administration (FDA) approved …

Extracellular Vesicle Characteristics And Micro Rna Content In Cerebral Palsy And Typically Developed Individuals At Rest And In Response To Aerobic Exercise., Ivan Jose Vechetti Jr, Jessica Norrbom, Björn Alkner, Emma Hjalmarsson, Alexandra Palmcrantz, Eva Pontén, Jessica Pingel, Ferdinand Von Walden, Rodrigo Fernandez-Gonzalo

Department of Nutrition and Health Sciences: Faculty Publications

In this study, the properties of circulating extracellular vesicles (EVs) were examined in cerebral palsy (CP) and typically developed (TD) individuals at rest and after aerobic exercise, focusing on the size, concentration, and microRNA cargo of EVs. Nine adult individuals with CP performed a single exercise bout consisting of 45 min of Frame Running, and TD participants completed either 45 min of cycling (n = 10; TD EX) or were enrolled as controls with no exercise (n = 10; TD CON). Blood was drawn before and 30 min after exercise and analyzed for EV concentration, size, and microRNA …

The Impact Of Habitual Dietary Fat Intake On Postprandial Lipemia In Older Adults, Sophia A. Bollinger

Masters Theses, 2020-current

Postprandial lipemia (PPL) is a risk factor for cardiovascular disease (CVD). Many older Americans experience elevated PPL due to a chronically high-fat diet and an inefficient ability to clear triglycerides (TG) from circulation. TG levels are typically measured in a fasted state; however, postprandial TG levels may be more strongly associated with CVD risk. This study grouped ten older adults into two dietary consumption fat categories and examined the response to an acute high-fat meal by measuring postprandial blood cholesterol, TG, and glucose (GLU) at baseline, 30-minutes post-meal, 60 minutes, 90 minutes, 120 minutes, 180 minutes, and 240 minutes. Participants …

Healthy Eating Index And Body Fat Distribution, Masar Ozrail

Theses and Dissertations

Body fat distribution has been identified as a more significant risk factor for metabolic-related diseases. This study investigated whether body fat distribution affects dietary outcomes (quality and intake), anthropometric measures, body composition, and skin carotenoid levels. A cross-sectional study with 91 female students was conducted. Thirty-one percent of participants (n=28) had an android body fat distribution. Body fat distribution was associated with WC and WHtR (p

Attitudes Towards Breastfeeding Among College Students At Mississippi State University, Kristin F. Williford

Theses and Dissertations

Breastfeeding rates in America are lower than other high-income countries, with Mississippi having one of the lowest rates. A survey using the Iowa Infant Feeding Attitude Scale (IIFAS) was distributed twice to Mississippi State University students to understand their breastfeeding attitudes. Attitudes were determined by calculating a composite score and conducting statistical tests for significance. Knowledge between health and non-health related majors were explored by using five statements, and attitudes towards the statement “Breastmilk is the ideal food for babies” were compared across demographics. Of 642 respondents, the composite score was 57.3 out of 85, and all demographics had a …

Changes In Depressive Symptoms, Perceived Stres, And Food Security Among Study Participants With Metabolic Syndrome During A Covid-19-Mandated Research Pause, Barbara A. Lohse, Anahi Ramirez, Jenna Hickey, Lisa Bailey-Davis, Betty Drees, Kevin S. Masters, Elizabeth H. Ruder, Nicole Trabold

Articles

Introduction: This study explored how food security, perceived stress and mental health of persons with metabolic syndrome (MetS) changed in the COVID-19 pandemic.

Methods: An online survey was administered to persons enrolled in a 2-year lifestyle intervention trial to reverse metabolic syndrome at baseline; the survey was repeated during the COVID-19 pandemic. Outcomes were a change in depressive symptoms, perceived stress, and food security as measured by the Patient Health Questionnaire-8, Cohen Stress Scale, and USDA 10-item Food Security Screener. Changes in outcomes were analyzed with measures of association, paired t-test, repeated measures and independent t-test.

Results: Participants (n = …

Assessment Of Novel Protein Ingredient Arthrospira Platensis (Microalgae) And Soybean Genotype Amino Acid And Oil Selection Improvements On Broiler Performance, Savannah Wells Crafton

Graduate Theses and Dissertations

Two experiments were conducted to assess the efficiency of including novel protein ingredient Arthrospira platensis or improved soybean meal in a broiler diet. The first experiment aimed to determine the feeding value of soybean meal produced from varieties of soybeans bred for increased amino acid content (SBAA) improved oil content (SBO) compared to a conventional soybean variety in an ANOVA design fed to Cobb 500 female broilers for 28-42d of age. The SBAA and SBO soybeans contained overall higher amino acid content and lower oligosaccharide content compared to the conventional soybean variety in addition to improved oil quality. The second …

Enhancing Amino Acid Utilization For Broiler Chickens Under Different Scenarios Of Dietary Protein Reduction And Subclinical Coccidiosis, Derrell Trevor Lee

Graduate Theses and Dissertations

Five experiments were conducted to evaluate responses of broiler chickens fed diets with different dietary amino acid (AA) levels when fed normal and reduced dietary crude protein (RCP) diets and reared under different coccidiosis control programs. In the studies with the use of RCP diets, the relationship between dietary Gly + Ser and the Met:Cys ratio was investigated. Experiment 1 evaluated broilers in 2 coccidiosis control programs (live vaccine or in-feed zoalene) and fed increased dietary AA derived from soybean meal or unbound sources from 0-40 d. Vaccination impaired young (0-26 d) broiler body weight gain (BWG) and feed conversion …

Predicting Personalized Responses To Dietary Fiber Interventions: Opportunities For Modulation Of The Gut Microbiome To Improve Health, Car Reen Kok, Devin J. Rose, Robert Hutkins

Department of Nutrition and Health Sciences: Faculty Publications

Inadequate dietary fiber consumption has become common across industrialized nations, accompanied by changes in gut microbial composition and a dramatic increase in chronic metabolic diseases.The human gut microbiome harbors genes that are required for the digestion of fiber, resulting in the production of end products that mediate gastrointestinal and systemic benefits to the host. Thus, the use of fiber interventions has attracted increasing interest as a strategy to modulate the gut microbiome and improve human health. However, considerable interindividual differences in gut microbial composition have resulted in variable responses toward fiber interventions. This variability has led to observed nonresponder individuals …

A Prophylactic Subcutaneous Dose Of The Anticoagulant Tinzaparin Does Not Influence Qpcr-Based Assessment Of Circulating Levels Of Mirna In Humans, Abraham Nilsson, Anna Maria Nerhall, Ivan Jose Vechetti Jr, Lotta Fornander, Simon Wiklund, Björn Alkner, Jörg Schilcher, Ferdinand Von Walden

Department of Nutrition and Health Sciences: Faculty Publications

Circulating microRNAs (miRNAs) have become increasingly popular biomarker candidates in various diseases. However, heparin-based anticoagulants might affect the detection of target miRNAs in blood samples during quantitative polymerase chain reaction (qPCR)- based analysis of miRNAs involving RNA extraction, cDNA synthesis and the polymerase catalyzed reaction. Because low-molecular-weight heparins (LMWH) are widely used in routine healthcare, we aimed to investigate whether a prophylactic dose of the LMWH tinzaparin influences qPCR-based quantification of circulating miRNAs. A total of 30 subjects were included: 16 fracture patients with tinzaparin treatment and 14 non-fracture controls without anticoagulation therapy. To control for the effect of tinzaparin …

The Effects Of Surface Composition On 6-Weeks Of Plyometric Training, Cameron D. Addie, Richard S. Farley, Sandra L. Stevens, Halle J. Brandt3, Jocelyn E. Arnett, Jennifer L. Caputo

Department of Nutrition and Health Sciences: Faculty Publications

Background: Plyometric training programs may be performed on a hard surface or a soft surface to target specific training adaptations and enhance jump performance. However, it is unknown how surface compliance impacts jump performance. Objective: To compare changes in horizontal lower body power following a 6-week plyometric training program performed on a soft surface (n = 9) and a hard surface (n = 11). Methods: This was a quasi-experimental study. University students (N = 20; males = 11, females = 9; age: 20.4 ± 3.7 yr; body mass: 68.4 ± 12.5 kg; height 1.7 …

Analysis Of The Relationship Between Children's Characteristics, Family Characteristics, Food Intake, Eating Habits, And Disease History With Nutritional Status Of Under-Five Children Based On The Composite Index Of Anthropometric Failure In Karangkamulyan Village, Cihara District, Lebak Regency, Indonesia In 2020, Ayu Anisadiyah, Ratu Ayu Dewi Sartika

Indonesian Journal of Public Health Nutrition (IJPHN)

The Composite Index of Anthropometric Failure (CIAF) is an indicator of composite nutritional status assessment (BB/U, PB/U, and BB/PB) to describe all under-five children’s nutritional problems. In 2020, malnutrition, unemployment, and poverty in Banten Province were high, and the population's income tends to be low. Karangkamulyan Village is an underdeveloped village with mining areas. This study aims to determine the factors related to the nutritional status of under-five children based on CIAF in Karangkamulyan Village in 2020. The study used a cross-sectional study design and a systematic random sampling technique. The research sample was 141 under-five children aged 24-59 months. …

Factors Associated With High Fat, Salt, And Sugar Food Selection On Online Food Delivery Service Among Students Of Sman (State High School) 47 Jakarta, Indonesia, In 2022, Arifiana Arifiana, Kusharisupeni Djokosujono, Wahyu Kurnia Yusrin Putra, Nina Muziana

Indonesian Journal of Public Health Nutrition (IJPHN)

In the use of Online Food Delivery Service (OFDS), an online service applying a smartphone to make it easier for users to get food quickly, it was found that the foods selected tend to be unhealthy and may increase the risk of being overweight. The aim of this study was to determine predominant and other factors that differ in food selection in OFDS among students at SMAN (State High School) 47 Jakarta in 2022. This study applied a cross-sectional study design with 112 subjects. Data were taken through a questionnaire and analyzed by using an X²- test and multiple logistic …

The Association Between Feeding Practices And History Of Diarrhea With Nutritional Status Of Toddlers, Lulu Indria Setyani, Khoirul Anwar

Indonesian Journal of Public Health Nutrition (IJPHN)

The age of 0-59 months is a phase of basic life formation that is vulnerable to nutritional problems—causes such as infectious diseases and parenting. This research aims to analyze the relationship between feeding practices and a history of diarrhea with the nutritional status of children under five. This study used a cross-sectional design. Samples were taken by purposive sampling of as many as 96 toddlers. Data were collected by direct measurement of weight scales, stature meters, and interviews using the main questionnaire and the modified CFQ questionnaire. The statistical tests used were the chi-square test and fisher's exact test. A …

Sleep Quality And Affecting Factors Among Elderly Living In A Nursing Home In East Nusa Tenggara Indonesia, Asyifa Robiatul Adawiyah, Kusharisupeni Djokosujono, Jumiati Lelu Sanga

Indonesian Journal of Public Health Nutrition (IJPHN)

Sleep is one of the processes that greatly affects aging, It is essential for mental, physical, and maintenance of physical health. A research study was conducted in a public nursing home in Kupang East Nusa Tenggara Indonesia. This study aimed to analyze the sleep quality and the factors affecting sleep quality, among old age living in the nursing home. The research design was cross-sectional with primary data on 103 elderly living in nursing homes. There was a relationship between age, gender, marital status, spouse, educational background, have a chronic disease, living arrangement, anxiety, and depression with sleep quality (p

Availability Of Sugar-Sweetened Beverages At Home As The Dominant Factor Related To Its Consumption Among Students Of Sman (State High School) 47 Jakarta, Indonesia, In 2022, Nadhira Winindya Sari, Kusharisupeni Djokosujono, Diah Mulyawati Utari, Neni Rohayati

Indonesian Journal of Public Health Nutrition (IJPHN)

Sugar-sweetened beverages (SSBs) are drinks added with simple sugar, which can increase the energy because of calorie-dense and high in sugar, but low in other nutrients. Excessive consumption of SSBs can cause nutritional problems, such as increasing the risk of overweight and obesity. This study aims to determine the relationship between SSBs consumption and various factor and the dominant factor of SSBs consumption among students of SMAN (State High School) 47 Jakarta in 2022. The cross-sectional study was conducted from November 2021 to June 2022 with 120 respondents. Primary data was taken using questionnaires and analyzed by univariate, bivariate (chi-square …

Plum Supplementation And Lipid Profile: A Systematic Review And Meta-Analysis Of Randomised Controlled Trials, Moein Askarpour, Hamid Ghalandari, Leila Setayesh, Ehsan Ghaedi

Department of Nutrition and Health Sciences: Faculty Publications

Plums are abundant in bioactive compounds which have been associated with numerous health benefits. In the present study, we aimed at examining the impact of plum supplementation on lipid profile of individuals. Electronic bibliographical databases were searched for relevant randomised clinical trials. Articles meeting our eligibility criteria were included for data extraction and final analysis. Weighted mean difference (WMD) was estimated using a random-effect model. Of the total articles retrieved in the initial search, nine articles were found to be eligible to be included in the analysis. Our results show that plum supplementation significantly improves total cholesterols levels in the …