Animal Sciences Commons^™

Genomic Characterization Of Highly Pathogenic H5 Avian Influenza Viruses From Alaska During 2022 Provides Evidence For Genotype-Specific Trends Of Spatiotemporal And Interspecies Dissemination, Christina A. Ahlstrom, Mia Kim Torchetti, Julianna Lenoch, Kimberlee Beckmen, Megan Boldenow, Evan J. Buck, Bryan Daniels, Krista Dilione, Robert Gerlach, Kristina Lantz, Angela Matz, Rebecca L. Poulson, Laura C. Scott, Gay Sheffield, David Sinnett, David E. Stallknecht, Raphaela Stimmelmayr, Eric Taylor, Alison R. Williams, Andrew M. Ramey

United States Department of Agriculture Wildlife Services: Staff Publications

The ongoing panzootic of highly pathogenic H5 clade 2.3.4.4b avian influenza (HPAI) spread to North America in late 2021, with detections of HPAI viruses in Alaska beginning in April 2022. HPAI viruses have since spread across the state, affecting many species of wild birds as well as domestic poultry and wild mammals. To better understand the dissemination of HPAI viruses spatiotemporally and among hosts in Alaska and adjacent regions, we compared the genomes of 177 confirmed HPAI viruses detected in Alaska during April–December 2022. Results suggest multiple viral introductions into Alaska between November 2021 and August or September 2022, as …

Wildlife Monitoring With Drones: A Survey Of End Users, Raymond B. Iglay, Landon R. Jones, Jared E. Elmore, Kristine O. Evans, Sathish Samiappan, Morgan B. Pfeiffer, Brad F. Blackwell

United States Department of Agriculture Wildlife Services: Staff Publications

Rapid advancements in technology often yield research inquiry into novel applications and drone (i.e., unoccupied aircraft systems or UAS) applications in wildlife management are no exception. We questioned the time lag between drone‐related research and end‐user assessments. We implemented an online, cross‐sectional survey of wildlife professionals to better understand current drone use and benefits or concerns, complemented by a review of contemporary peer‐reviewed and gray literature. We found little disparity between scientific inquiry and end‐user experiences (i.e., similar trends among concerns in published literature and survey results). Exploring new (i.e., advancements in computer vision) and refining original drone applications (i.e., …

Comparing Efficiencies Of Population Control Methods For Responding To Introductions Of Transboundary Animal Diseases In Wild Pigs, Nathan P. Snow, Benjamin Smith, Michael J. Lavelle, Michael P. Glow, Kayleigh Chalkowski, Bruce R. Leland, Sarah Sherburne, Justin W. Fischer, Keely J. Kohen, Seth M. Cook, Hatton Smith, Kurt C. Vercauteren, Ryan S. Miller, Kim M. Pepin

United States Department of Agriculture Wildlife Services: Staff Publications

Introductions of transboundary animal diseases (TADs) into free-ranging wildlife can be difficult to control and devastating for domestic livestock trade. Combating a new TAD introduction in wildlife with an emergency response requires quickly limiting spread of the disease by intensely removing wild animals within a contiguous area. In the case of African swine fever virus (ASFv) in wild pigs (Sus scrofa), which has been spreading in many regions of the world, there is little information on the time- and cost-efficiency of methods for intensively and consistently culling wild pigs and recovering carcasses in an emergency response scenario. We compared the …

Temporal And Spatial Influences On Fawn Summer Survival In Pronghorn Populations: Management Implications From Noninvasive Monitoring, Cole A. Bleke, Eric M. Gese, Juan J. Villalba, Shane B. Roberts, Susannah S. French

United States Department of Agriculture Wildlife Services: Staff Publications

Monitoring vital rates allowsmanagers to estimate trends in growth rates of ungulate populations. However, connecting the influence of nutrition on ungulate demography is challenging. Noninvasive sampling offers a low-cost, low-effort alternative for measuring nutritional indices, allowing for an increased understanding of the mechanistic relationships between environmental factors, nutrition, and specific population vital rates. We examined the temporal influence of intrinsic and extrinsic factors on pronghorn (Antilocapra americana) fawn recruitment. We collected fresh fecal samples from adult female pronghorn in five subpopulations spanning three sampling periods associated with critical maternal life-history stages (late gestation, early lactation, breeding season) for …

Susceptibilities And Viral Shedding Of Peridomestic Wildlife Infected With Clade 2.3.4.4b Highly Pathogenic Avian Influenza Virus (H5n1), J. Jeffrey Root, Stephanie M. Porter, Julianna B. Lenoch, Jeremy W. Ellis, Angela M. Bosco-Lauth

United States Department of Agriculture Wildlife Services: Staff Publications

We tested the ability of six peridomestic wildlife species to replicate a highly pathogenic (HP) clade 2.3.4.4b AIV (H5N1) isolated in the United States during 2022. All tested species replicated and shed virus, at least to some degree. Of the six species evaluated (house sparrows (Passer domesticus), European starlings (Sturnus vulgaris), feral pigeons (Columba livia), striped skunks (Mephitis mephitis), Virginia opossums (Didelphis virginiana), and cottontails (Sylvilagus sp.)), striped skunks and Virginia opossums shed the highest viral titers of 106.3 PFU/mL and 105.0 PFU/mL, respectively. Overall, the results of this …

Chronic Wasting Disease Effects On A Breeding Season Behavior In White-Tailed Deer (Odocoileus Virginianus), Miranda Hsiang-Ning Jacobson Huang, Stephen Demarais, Bronson K. Strickland, Allan Houston, Alejandro Banda, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

Wildlife disease outbreaks can lead to population declines, which are usually attributed to increased direct or indirect mortality. Alternatively, behavior associated with sickness can lead to social isolation, potentially decreasing fitness of affected individuals. A useful case study to examine this dynamic is chronic wasting disease (CWD), a neurological disease of cervids, known to affect behavior and movement. In this study, we monitored scraping, a White-tailed Deer (Odocoileus virginianus; WTD) breeding season behavior, in an area of high CWD prevalence to determine if this reproductive behavior is affected by CWD. At 107 scrape sites, we detected 3,063 scrape interactions and …

Trichinella Murrelli Identified In Red Foxes (Vulpes Vulpes) In Pennsylvania, Usa, Jitender Dubey, Peter C. Thompson, Larissa S. De Araujo, Aditya Gupta, Sasha Kay, Oliver C. H. Kwok, Jaquin Battle, Kyle R. Van Why, Justin D. Brown, Benjamin Rosenthal

United States Department of Agriculture Wildlife Services: Staff Publications

Trichinella infections have been eliminated from pork where pigs are raised in biosecure facilities, but wildlife infections persist. Trichinella murrelli is the primary zoonotic species in wild carnivores in the United States, having been identified in several species of omnivores and carnivores. Here, we document its occurrence in seven of 21 (33.3%) red foxes (Vulpes vulpes) from six counties in Pennsylvania. Encysted Trichinella juveniles were detected in muscle squashes (< 5 g samples) of all seven foxes, and in histological sections of the tongue and limb muscle of three. Juveniles from muscle squashes were pooled and tested in a multiplex PCR capable of differentiating all Trichinella species native to the USA; all samples contained only T. murrelli. This is the first identification of T. murrelli in red foxes from Pennsylvania, …

Heating Decoys To Mimic Thermal Signatures Of Live Animals For Drones, Landon R. Jones, Cerise Mensah, Jared S. Elmore, Kristine O. Evans, Morgan B. Pfeiffer, Brad F. Blackwell, Raymond B. Iglay

United States Department of Agriculture Wildlife Services: Staff Publications

Method name

Heating animal decoys to mimic thermal signatures for drones

Abstract

Thermal sensors mounted on drones (unoccupied aircraft systems) are popular and effective tools for monitoring cryptic animal species, although few studies have quantified sampling error of ani- mal counts from thermal images. Using decoys is one effective strategy to quantify bias and count accuracy; however, plastic decoys do not mimic thermal signatures of representative species. Our objective was to produce heat signatures in animal decoys to realistically match thermal images of live animals obtained from a drone-based sensor. We tested commercially available methods to heat plastic decoys of …

Competitive Behaviors Between Black Vultures (Coragyps Atratus) And Turkey Vultures (Cathartes Aura) During Scavenging / Comportamientos Competitivos Entre Coragyps Atratus Y Cathartes Aura Durante El Carroñeo, Amanda M. Herbert, Patrick A. Zollner, Landon R. Jones, Marian L. Wahl, Grant N. Burcham, Bryan M. Kluever, Lee A. Humberg, Brandon M. Quinby

United States Department of Agriculture Wildlife Services: Staff Publications

Abstract

Interference competition occurs when an individual prohibits another’s access to a resource through antagonistic interactions. Despite considerable research on scavenger interactions at carrion, the limited evidence for competitive interactions between black vultures (Coragyps atratus) and turkey vultures (Cathartes aura) relies upon the frequency of antagonistic interactions without considering other forms of competition. Using remote cameras, we recorded the duration of aggression, scavenging, and vigilance behaviors exhibited by individual black vultures and turkey vultures scavenging stillborn domestic cattle carcasses within flocks composed of one or both vulture species. We tested for differences of durations of each …

The Texas Feral Swine Eradication And Control Pilot Program, David R. Pipkin, Bruce R. Leland, Katherine Garwood, Linda Tschirhart-Hejl, Michael J. Bodenchuk, John M. Tomecek

United States Department of Agriculture Wildlife Services: Staff Publications

The United States Agriculture Improvement Act of 2018 (the 2018 Farm Bill) established the Feral Swine Eradication and Control Pilot Program. The program funded US$75M for 5 years, split evenly between the Natural Resources Conservation Service (NRCS) and the Animal and Plant Health Inspection Service (APHIS), both programs within the United States Department of Agriculture. The agencies solicited joint programs from states with high densities of feral swine in two phases. In Texas, NRCS and APHIS submitted three multi-county project areas along watersheds for Phase I funding and one eradication effort along with two crop protection projects in Phase II. …

Spatiotemporal Partitioning Of Two Invasive Ungulates In Guam [Abstract], Kelly J. Koriakin, Kurt C. Vercauteren, Nathan P. Snow, D. Buck Jolley

United States Department of Agriculture Wildlife Services: Staff Publications

Interspecific interactions are crucial in shaping ecosystem dynamics (Connell 1983, Tilman 1987, Barbosa and Castellanos 2005). Non-native ungulates have been introduced across the globe (Ferretti and Lovari 2014, Volery et al. 2021) and in environments where multiple invasives thrive, these co-occurring sympatric species may shift spatiotemporal patterns to minimize interspecific competition (Schoener 1974, Chesson 2000). Spatiotemporal shifts can lead to cascading effects to the native flora and fauna (Simberloff and Von Holle 1999). Given the potential negative impacts, understanding these interactions is vital for effective management of these ecosystems.

Two invasive ungulates, the wild pig (Sus scrofa) and …

The Influence Of Social And Spatial Processes On The Epidemiology Of Environmentally Transmitted Pathogens In Wildlife: Implications For Management, Aakash Pandey, Chris Wojan, Abigail Feuka, Meggan E. Craft, Kezia Manlove, Kim M. Pepin

United States Department of Agriculture Wildlife Services: Staff Publications

Social and spatial structures of host populations play important roles in pathogen transmission. For environmentally transmitted pathogens, the host space use interacts with both the host social structure and the pathogen’s environmental persistence (which determines the timelag across which two hosts can transmit). Together, these factors shape the epidemiological dynamics of environmentally transmitted pathogens. While the importance of both social and spatial structures and environmental pathogen persistence has long been recognized in epidemiology, they are often considered separately. A better understanding of how these factors interact to determine disease dynamics is required for developing robust surveillance and management strategies. Here, …

Surveillance Of Highly Pathogenic Avian Influenza Virus In Wild Canids From Pennsylvania, Usa, Kevin D. Niedringhaus, Taylor C. Chan, Ashley Mcdowell, Lauren Mxwell, Madison Stevens, Lane Potts, Erica Miller, Eman Anis, Kyle Van Why, Thomas Keller, David Stallknecht, Rebecca L. Poulson, Kaitlyn Bahrs, Justin D. Brown

United States Department of Agriculture Wildlife Services: Staff Publications

The avian influenza virus is a global pathogen with significant health and economic implications. While primarily a pathogen of wild and domestic birds, recent outbreaks of the H5N1 highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4b have caused mortality in a wide variety of mammals, including members of the Canidae family, on multiple continents. Despite sporadic mortality events globally, the epidemiology and pathobiology of H5N1 HPAIV in wild canids remains poorly defined. During 2022–2024, 41 wild canid carcasses (diagnostic cases), including 23 red foxes and 18 gray foxes, were tested for the influenza A virus (IAV) via PCR, with five …

Rabies, Amy T. Gilbert, Christine Ellis

United States Department of Agriculture Wildlife Services: Staff Publications

Illustrated fact sheet on rabies.

Economic Valuation Model Of Vanname Shrimp Culture And Mangrove Rehabilitation, Elrin Meivian Mongi Mongi, Mahawan Karuniasa, Mufti Petala Patria

Journal of Environmental Science and Sustainable Development

The current climate change is caused by anthropogenic activities involving energy and industry usage that affect the temperature and climate of the Earth. The Paris Agreement on climate change is a commitment by some countries to act to address climate change by developing sustainably and emitting low levels of carbon dioxide (CO2). Changes in the oceans include temperature increases, acidification, and changes in currents, leading to decreased productivity in fishing and aquaculture. Integrated mangrove shrimp farming, known as silvofisheries, has been recognized as environmentally friendly cultivation. The implementation of silvofishery is a form of mangrove ecosystem management that integrates ecology …

Community Structure Of Sea Urchin As An Indicator Of The Ecological Balance Of Coastal Areas, Abdul Wahab Radjab, Intan Rabiyanti, Fiqih Muharby

Journal of Environmental Science and Sustainable Development

Sea urchins, soft-shelled invertebrates (Echinoderms), crucially contribute to cleaning the ocean bottom. However, sea urchins in tropical waters like Indonesia have not yet been fully disclosed. This study was conducted at Hutumuri and Rutong waters, Ambon City. This study assessed physical-chemical parameters, sea urchin species composition, classification, and community structure. Employing the Line Transect method with 5x5 m quadrants and 50m transect spacing, data analysis included density, relative density, frequency of presence, diversity, uniformity, and dominance indices. Results indicated normal temperature and salinity at both stations, supporting sea urchin life, with rocky and sandy substrates deemed suitable. A total of …

Review On Locusta Migratoria Cinerascens (Fabricius, 1781)., Laib Djamel Eddine, Benzehra Abdelmadjid, Laib Imen, Aouzal Badis, Salah Akkal

Journal of Bioresource Management

The migratory locust, scientifically known as Locusta migratoria (Linnaeus, 1758), is a captivating insect species that has drawn the interest of scientists, farmers, and the general public. Recognized for its notorious swarming behavior, this insect has the potential to cause extensive damage to crops, leading to agricultural plagues and food shortages. However, beyond its reputation as a pest, the migratory locust is a subject of scientific fascination due to its intricate life cycle, remarkable ability to undergo rapid and dramatic transformations, and its crucial role within the ecosystems it inhabits. This review delves into various facets of L. migratoria, including …

Moth Species Diversity, Composition And Abundance In Different Land Use Types Of Chebera Churchura National Park And Its Surroundings, Southwestern Ethiopia, Gebreegziabher Hailay, Emana Getu

Journal of Bioresource Management

Land use change and habitat fragmentation affect biodiversity through an increasing level of disturbance and destruction of natural habitats. The present study is the first report on species diversity, species composition, and abundance of moth fauna in and around Chebera Churchura national park. During the survey from January to June 2021, 6206 specimens were collected from 105 species and 11 families from the 3 land use types. Based on the number of species, the family Erbidae is the most abundant with 41 species, and the family Pyraldae was the least abundant with one species. Based on the number of individuals, …

Establishment Of Hand Rearing Protocols With Respect To Feeding, Physiological And Behavioral Aspects In Abandoned Lion Cubs At Safari Zoo Lahore, Muhammad Azhar, Bushra Nisar Khan, Fahd Haseeb, Muhammad Hassan Saleem, Abdul Rehman, Zahid Iqbal Khan, Muhammad Rizwan Khan

Journal of Bioresource Management

African lion (Panthera leo) being most attractive but vulnerable exhibit of zoos and safaris; need particular attention to breeding plans. At captive sites, lioness neglects newborns commonly; at that stage, hand rearing is preferred. This study will highlight the best practices for hand-rearing lion cubs, including knowledge of early medical issues along with their treatment during the first 4 months of growth. 34 lions (08Male: 17Females: 9Cubs) were housed on 15 acres during 2019-21 at Safari Zoo Lahore. A total of 04 lionesses were found entirely abandoned to 05 newborns (03 males & 02 females). The hand-rearing period …

The Role Of Cooperatives And Farmer-Industry Linkages In The Evolution Of Tanga’S Dairy Innovation System, Hezron Makundi, Heric Thomas

Journal of Humanities and Social Sciences

This study investigated the development of Tanga’s dairy innovation system and its role in promoting and maintaining relationships between farmers, the industry, and cooperative unions; employing a case study approach. The main objective was to assess the role of cooperatives in forging farmer-industry linkages and in improving dairy industry innovations. 100 dairy producers in Tanga participated in the survey that led to the paper. A questionnaire was used to collect data from randomly selected farmers. Furthermore, 20 key informant interviews were conducted with various participants, including the Tanga Dairy Cooperative Union livestock extension service providers. Also, one Focus Group Discussion …

Utilizing An Extract From Endophytic Fungus, Alternaria Alternata, Isolated From Ricinus Communis L. Leaves As A Biological Agent For Controlling The Migratory Locust In Algeria, Laib Djamel Eddine, Benzehra Abdelmadjid, Laib Imen, Aouzal Badis, Akkal Salah

Journal of Bioresource Management

In this research, we aimed to explore the insecticidal potential of Alternaria alternata, an endophytic fungus derived from the leaves of castor oil plant. To test its insecticidal efficacy, various doses of A. alternata mycoextract were administered to Locusta migratoria L. through both topical and oral pathways. The findings revealed that the insects displayed the highest susceptibility to a concentration of 2 g/L, leading to an impressive mortality rate of 87.5 % and 93.75 % for topical and oral administrations, in the same order. The extract displayed remarkable insecticidal properties, demonstrating LC50 values of 1.09 g/L for the topical …

Fungicide Data, Amber Johnson

ScholarsArchive Data

This dataset contains emergence, biomass, and fungal biomass data collected during a laboratory study examining the effects of soil fungal level and seed coating treatment on the growth of bluebunch wheatgrass (Pseudoroegneria spicata). Pathogenesis from soil and seed-borne fungus can limit success when restoring native species. Fungicides can combat fungal pathogens, but in some studies, fungicides treatments are ineffective at improving seedling emergence over untreated, control seed. These studies suggest low fungal presence due to dry conditions may be the cause of the ineffectiveness of fungicide treatments for some years and sites. This study tested if fungicide treatment …

Anti-Apostatic Feeding Behavior In Two Species Of Assassin Bug, The White-Spotted Assassin Bug Platymeris Biguttatus And Red-Spotted Assassin Bug Platymeris Rhadamanthus (Hemiptera: Reduviidae), Julia H. Potocnjak, Christopher Vitek

School of Integrative Biological & Chemical Sciences Faculty Publications

Predator-prey relationships are a driving force when examining community ecology. One question in predator-prey interactions is how a predator may respond to novel prey phenotypes, a form of frequency dependent prey selection. A predator may selectively target or avoid the novel prey, a behavior referred to as anti-apostatic or apostatic selection respectively. We examined apostatic prey selection by observing feeding behavior in two species of assassin bugs (Hemiptera: Reduviidae), the white-spotted assassin bug (Platymeris biguttatus) and the red-spotted assassin bug (Platymeris rhadamanthus) which were fed unmodified and modified (novel) phenotypes of Turkistan cockroaches, Blatta lateralis (Blattodea: …

Oregon State Rank Assessment For Pit Roach (Hesperoleucus Mitrulus), Misty Nelson

Institute for Natural Resources Publications

Oregon state conservation status assessment for pit roach (Hesperoleucus mitrulus) using NatureServe methodology, 2023.

Comprehensive Assessment Of Economic, Productive, Phenotypic, And Morphometric Traits In Azikheli Buffalo Breed Of Northern Pakistan, Nadar Khan, Bakhtawara Bibi, Tariq Ahmad, Salman Khan, Aamir Khan, Muhammad Ibrahim

Journal of Bioresource Management

The study was conducted to illuminate the phenotypic, morphometric, and productive characteristics of the Azikheli buffalo breed. One thousand two hundred pure Azikheli buffaloes (male: female) were randomly selected from the main hub of the Azikheli buffalo breed in Swat (Azikhel). The data were analyzed for comparison and frequency distribution. Phenotypic characteristic of the female buffalo shows that more than 73 % of the body color was golden yellowish. In contrast, in males, this value was 83 %, followed by white-albino and grayish colors. The shape of horns were semi sickle and grayish in color. Morphometric parameters of the breed …

Hepatoprotective Effect Of Berberis Lycium In Αlpha-Naphthylisothiocyanate Induced Cholestatic Mouse Models, Shamaila Bashir, Hassan Hameed, Nida Irshad, Aqsa Ashraf, Muhammad Faizan, Saiyada Fatima Maida Halim, Hafiz M. Mazhar Asjad, Andleeb Batool, Imran Sohail

Journal of Bioresource Management

Cholestasis is characterized by the obstruction of bile flow from hepatocytes to the intestine. It results in accumulation of bile acids in the liver, which cause oxidative stress, inflammation, apoptosis, fibrosis, and cirrhosis. Till now, the treatment options against cholestasis are limited. Therefore, there is an utmost requirement to develop and evaluate the drugs with potential anti-cholestatic effects. In the current study, the drug-induced cholestasis mouse models were generated via oral administration of α-naphthylisothiocyanate (ANIT). The mice were placed into three groups of six animals each. Group I was the control group and was given saline. The cholestasis model Group …

Optimizing Conservation Of Nili Ravi Buffaloes In Southern Region Of Khyber Pakhtunkhwa: A Comprehensive Evaluation Of Phenotypic, Morphometric, And Productive Traits, Arsalan Khan, Israr Ud Din, Hafiz Abdul Majid, Amjad Ali, Akhtar Ali, Muhammad Rizwan, Waseem Ullah, Shah Zeb, Safi Ullah, Imran Khan, Abid Ullah

Journal of Bioresource Management

In Pakistan, Nili Ravi buffalo is highly valued breed due to its high milk yield. Native to Punjab province, the breed is now extensively distributed throughout the country. To assess and optimize the conservation strategies for Nili Ravi buffaloes in southern Khyber Pakhtunkhwa by evaluating their phenotypic, morphometric, productive, and reproductive characteristics. Buffaloes were maintained at Livestock Research and Development Station in Paharpur, Dera Ismail Khan from 2010-2023, under breed conservation program. A sum of 298 records Nili Ravi buffaloes were used for the investigation. The research examined physical attributes such as coat color, horn morphology, and other qualitative characteristics. …

Feeding Overlap Investigations Between Hypophthalmichthys Molitrix And Cyprinus Carpio From Punjab, Pakistan, Afzala Munawar, Muhammad Imran, Muhammad Ameen, Abdul Majid Khan, Ayesha Sania, Muhammad Shahbaz

Journal of Bioresource Management

Freshwater ichthyofauna is facing intensive stress as a result of urbanization and growing industries in Pakistan. The alien fish species are considered one of the major challenges due to their deleterious effects. Feeding habit analysis is a basic tool to evaluate the ecological stress on fish species residing in different habitats. The present study was designed to disclose the feeding overlap between Cyprinus carpio (Common Carp) and Hypophthalmichthys molitrix (Silver Carp) from Head Marala (river Chenab) and Mangla Dam (river Jhelum). For this purpose, 20 samples i.e. 10 from each site of each fish species out of total 40, were …

Biology, Ecology, Infestation, And Management Of Warble Flies (Diptera: Oestridae), Muhammad Jamil, Abdul Razzaq, Noman Latif, Mariam Fatima, Muhammad Saqib, Matiullah Jaffar, Hafiz Zille Rehman, Faiqah Ramzan

Journal of Bioresource Management

The range grazing livestock (cattles and goats) are afflicted by a significant skin/hide issue known as warble fly larval infestation, which is caused by the larvae of Hypoderma lineatum and Hypoderma bovis species which resulted in substantial economic losses to the leather industries. The life cycle of hypodermosis is complex, involving both ecto- and endoparasitic stages. Female warble flies deposit their eggs in rows of 5-8 on individual hairs of the host, often targeting the legs but also other areas. These eggs are securely attached to the hairs and a single female fly may lay as many as 800 eggs …

Palmitate Induces Integrated Stress Response And Lipoapoptosis In Trophoblasts, Prakash Kumar Sahoo, Chandan Krishnamoorthy, Jennifer R. Wood, Corrine Hanson, Ann Anderson-Berry, Justin L. Mott, Sathish Kumar Natarajan

Department of Animal Science: Faculty Publications

Maternal obesity increases the risk of childhood obesity and programs the offspring to develop metabolic syndrome later in their life. Palmitate is the predominant saturated free fatty acid (FFA) that is transported across the placenta to the fetus. We have recently shown that saturated FFA in the maternal circulation as a result of increased adipose tissue lipolysis in third trimester of pregnancy induces trophoblast lipoapoptosis. Here, we hypothesized that palmitate induces integrated stress response by activating mitogen-activated protein kinases (MAPKs), endoplasmic reticulum (ER) stress and granular stress and lipoapoptosis in trophoblasts. Choriocarcinoma-derived third-trimester placental trophoblast-like cells (JEG-3 and JAR) referred …