Open Access. Powered by Scholars. Published by Universities.®

Engineering Commons™

Open Access. Powered by Scholars. Published by Universities.®

2019

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 8971 - 9000 of 10505

Full-Text Articles in Engineering

Learning Models For Corrupted Multi-Dimensional Data: Fundamental Limits And Algorithms, Ishan Jindal Jan 2019

Learning Models For Corrupted Multi-Dimensional Data: Fundamental Limits And Algorithms, Ishan Jindal

Wayne State University Dissertations

Developing machine learning models for unstructured multi-dimensional datasets such as datasets with unreliable labels and noisy multi-dimensional signals with or without missing information have becoming a central necessity. We are not always fortunate enough to get noise-free datasets for developing classification and representation models. Though there is a number of techniques available to deal with noisy datasets, these methods do not exploit the multi-dimensional structures of the signals, which could be used to improve the overall classification and representation performance of the model.

In this thesis, we develop a Kronecker-structure (K-S) subspace model that exploits the multi-dimensional structure of the …


Utilizing Immunopet To Measure Tumor Response To Treatment In Breast Cancer, Brooke Mcknight Jan 2019

Utilizing Immunopet To Measure Tumor Response To Treatment In Breast Cancer, Brooke Mcknight

Wayne State University Dissertations

With a broad spectrum of therapies available for treating breast cancer, the need for personalized medicine tailoring the cure according to phenotype is evident. Such an approach may be fully realized with the development of quantitative imaging technologies for disease detection, staging and diagnosis, without increasing patient burden. Immuno-positron emission tomography (PET) combines the targeted specificity of antibodies with the sensitivity of PET for whole body imaging by targeting molecular features amplified in lesions. ImmunoPET probes targeting different antigens and their utility to measure response to treatment were explored. 89Zr-trastuzumab was employed as a surrogate readout of Src inhibition after …


An Approach To Evaluate Disability Using Machine Learning And Sensor-Equipped Instruments Demonstrated On Hand Grip Force Data, Prem Kumar Sivakumar Jan 2019

An Approach To Evaluate Disability Using Machine Learning And Sensor-Equipped Instruments Demonstrated On Hand Grip Force Data, Prem Kumar Sivakumar

Wayne State University Dissertations

The goal of this research is to improve the process of rehabilitation. Even though the current tools and technologies are meeting the requirements of clinical use, there is a lot of room for improvement. Improving the tools used in therapy can help reduce costs and save time for the patient and the therapist by giving a valuable insight into the progress of the therapeutic process. Combining therapeutic tools with cognitive tools such as machine learning can assist a therapist to determine and predict functional ability and help patients keep track of their progress.

The long-term goal for instrumented outcome measures …


Analysis And Mitigation Of The Impacts Of Delays In Control Of Power Systems With Renewable Energy Sources, Chang Fu Jan 2019

Analysis And Mitigation Of The Impacts Of Delays In Control Of Power Systems With Renewable Energy Sources, Chang Fu

Wayne State University Dissertations

ABSTRACT

Analysis and Mitigation of the Impacts of Delays in Control of Power Systems

with Renewable Energy Sources

by

Chang Fu

Apr. 2019

Advisor : Dr. Caisheng Wang

Major : Electrical and Computer Engineering

Degree : Doctor of Philosophy

With the integration of renewable resources, electric vehicles and other uncertain

resources into power grid, varieties of control topology and algorithms have been proposed to

increase the stability and reliability of the operation system. Load modeling is an critical part

in such analysis since it significantly impacts the accuracy of the simulation in power system,

as well as stability and reliability …


Automatic Resource Management And Performance Optimization In Clusters, Yudi Wei Jan 2019

Automatic Resource Management And Performance Optimization In Clusters, Yudi Wei

Wayne State University Dissertations

Virtual machine is a primary way to increase resource utilizations in data centers by encapsulating multi-resource demands for applications and providing performance isolation. Moreover, the resource configuration can change on the fly to satisfy performance target. Container is another popular way for fine-grained multi-resource allocation. In this disser- tation work, we aim to design and implement an automatic resource management system to improve application performance, optimize system efficiency and job completion times in virtual and physical clusters respectively.

For large-scale applications hosted in data center, automatic resource configuration is crucial to service availability and quality. The workload dynamics, cloud dynamics …


Post-Earthquake Assessment And Numerical Modeling Of Freestanding Heritage Structures, M. Khalid Saifullah, Christine E. Wittich Jan 2019

Post-Earthquake Assessment And Numerical Modeling Of Freestanding Heritage Structures, M. Khalid Saifullah, Christine E. Wittich

Department of Civil and Environmental Engineering: Faculty Publications

Historic and heritage structures are particularly vulnerable to earthquakes, where damage or collapse can not only lead to loss of a structure but also the loss of irreplaceable heritage. Many heritage structures can be classified as freestanding (detached) structures, including unreinforced masonry walls, classical multi-drum columns, and statue-pedestal systems. However, the seismic response of freestanding structures (sliding, rocking, rock-slide, overturning) is poorly predicted by existing methods due to geometric non-linearities as well as sensitivity to interface conditions and modeling parameters. Previous studies have focused on analytical modeling of simplified systems and/or experimentation under controlled laboratory conditions. In contrast, this paper …


Post-Fire Damage Geospatial Assessment Via Point Clouds Of A Highway Bridge Structure, Yijun Liao, M Ebrahim Mohammadi, Richard L. Wood, Christine E. Wittich Jan 2019

Post-Fire Damage Geospatial Assessment Via Point Clouds Of A Highway Bridge Structure, Yijun Liao, M Ebrahim Mohammadi, Richard L. Wood, Christine E. Wittich

Department of Civil and Environmental Engineering: Faculty Publications

This paper discusses the quantitative post-fire damage assessment of a steel girder bridge via point clouds. In this case study, the point cloud was collected using light detection and ranging (lidar) for a detailed geometric and shape analysis. The out-of-plane deformation was analyzed to locate and quantify buckling across the length of the steel girders.


Efficient Intensity Measures Of Slide-Rocking Structures For Precariously Balanced Rocks, Taylor J. Knickerbocker, Christine E. Wittich Jan 2019

Efficient Intensity Measures Of Slide-Rocking Structures For Precariously Balanced Rocks, Taylor J. Knickerbocker, Christine E. Wittich

Department of Civil and Environmental Engineering: Faculty Publications

Precariously balanced rocks (PBRs) and other fragile geologic features are important in both the engineering and seismological communities since they are indicative of the maximum ground motion at a site over the rock’s lifetime. Precariously balanced rocks are individual or stacks of freestanding rocks that tend to respond in rigid body modes when subject to seismic excitation – namely, rocking, sliding, slide-rocking, and free-flight, which can lead to overturning. The seismic response of freestanding structures, such as PBRs, is known to be extremely sensitive to small changes in geometry, position, and earthquake excitation. As such, deterministic methods are limited in …


Design And Investigation Of Genetic Algorithmic And Reinforcement Learning Approaches To Wire Crossing Reductions For Pnml Devices, Alexander Keith Gunter Jan 2019

Design And Investigation Of Genetic Algorithmic And Reinforcement Learning Approaches To Wire Crossing Reductions For Pnml Devices, Alexander Keith Gunter

Electronic Theses and Dissertations

Perpendicular nanomagnet logic (pNML) is an emerging post-CMOS technology which encodes binary data in the polarization of single-domain nanomagnets and performs operations via fringing field interactions. Currently, there is no complete top-down workflow for pNML. Researchers must instead simultaneously handle place-and-route, timing, and logic minimization by hand. These tasks include multiple NP-Hard subproblems, and the lack of automated tools for solving them for pNML precludes the design of large-scale pNML circuits.


Evaluating The Use Of Suas-Derived Imagery For Monitoring Flood Protection Infrastructure, Eleanor Mei Dietz Jan 2019

Evaluating The Use Of Suas-Derived Imagery For Monitoring Flood Protection Infrastructure, Eleanor Mei Dietz

Electronic Theses and Dissertations

In the US there are approximately 33,000 miles of levees. This includes 14,500 miles of levee systems associated with US Army Corps of Engineers programs and approximately 15,000 miles from other state and federal agencies. More than 14 million people live behind levees and associated flood prevention infrastructure. Monitoring and risk assessment are an on-going process, especially during times of flood conditions. The city of New Orleans was heavily impacted by Hurricane Katrina in 2005 by storm surges and intense rainfall. The impact of the hurricane was substantial enough to cause levee failure and I-wall toppling where many of the …


Raptor Codes For Biawgn Channel: Snr Mismatch And The Optimality Of The Inner And Outer Rates, Hussein Fadhel Jan 2019

Raptor Codes For Biawgn Channel: Snr Mismatch And The Optimality Of The Inner And Outer Rates, Hussein Fadhel

Electronic Theses and Dissertations

Fountain codes are a class of rateless codes with two interesting properties, first, they can generate potentially limitless numbers of encoded symbols given a finite set of source symbols, and second, the source symbols can be recovered from any subset of encoded symbols with cardinality greater than the number of source symbols. Raptor codes are the first implementation of fountain codes with linear complexity and vanishing error floors on noisy channels. Raptor codes are designed by the serial concatenation of an inner Luby trans-form (LT) code, the first practical realization of fountain codes, and an outer low-density parity-check (LDPC) code. …


Magnetic Amphiphiles And Their Potential Applications For Low Energy Separations Processes, Alexander Fortenberry Jan 2019

Magnetic Amphiphiles And Their Potential Applications For Low Energy Separations Processes, Alexander Fortenberry

Electronic Theses and Dissertations

Predicting the behavior of magnetic surfactants in magnetic fields is critical for designing magnetically driven processes such as chemical separations or the tuning of surface tensions. Our work supports the hypothesis that the ability of magnetic fields to alter the interfacial properties of magnetic surfactant solutions depends on the strength of association between the magnetic and surfactant moieties of the surfactant molecules. Our research shows that the stability of a magnetic surfactant in an aqueous environment is dependent upon the type of complex that contains the paramagnetic element and these findings provide valuable insight for the design of magnetic surfactants …


Investigative Study Of Poly(Ionic) Liquid Incorporation In Resin Wafer Electrodeionization For Improved Specific Energy Consumption, Angela Fasuyi Jan 2019

Investigative Study Of Poly(Ionic) Liquid Incorporation In Resin Wafer Electrodeionization For Improved Specific Energy Consumption, Angela Fasuyi

Electronic Theses and Dissertations

An electrokinetic separation method known as Resin Wafer Electrodeionization (RW-EDI) is recognized as a promising technology for energy efficient desalination of brackish water. However RW-EDI is limited by an inherent drawback of its ion exchange media that prevents the largescale deployment of this technology. This research was undertaken to optimize the conventional resin wafer used in RW-EDI through the incorporation of high conducting polyionic liquids (PILs). It was hypothesized that by the changing non-conducting polyethylene binder with a PIL binder in conventional resin wafer configurations ion conductivity within the resin bed would be enhanced and could lead to an improvement …


Molecular Dynamics Study Of Sintering Behavior Of Single-Crystal, Bimetallic Core/Shell Alloy, And Intermetallic Alloy Nanoparticles, Jungmin Jeon Jan 2019

Molecular Dynamics Study Of Sintering Behavior Of Single-Crystal, Bimetallic Core/Shell Alloy, And Intermetallic Alloy Nanoparticles, Jungmin Jeon

Electronic Theses and Dissertations

There has been rapidly growing interest in the sintering process of nanoparticles (NPs) among academia and modern industry due to their promising applications in additive manufacturing (AM) based on the overall improved properties at nanoscale. In the past decade a lot of experimental and computational work has been conducted to study the sintering process of powder materials. However there is still a significant knowledge gap in a fundamental understanding of the thermodynamics and nanostructural evolution of NPs undergoing additive manufacturing. This thesis aims to gain fundamental insights into melting behavior of different materials including single-crystal bimetallic core/shell alloy and intermetallic …


Developing A Calibrated Seepage Meter To Measure Stream-Aquifer Interaction In The Mississippi Delta, Wesley J. Bolton Jan 2019

Developing A Calibrated Seepage Meter To Measure Stream-Aquifer Interaction In The Mississippi Delta, Wesley J. Bolton

Electronic Theses and Dissertations

The Mississippi Alluvial Plain (MAP) is a premier region for irrigated agriculture in the United States producing approximately 9 billion dollars in annual revenues. The region receives around 138 cm of precipitation annually; however irrigation is necessary to maximize crop yields as most of the precipitation does not occur during the growing season. There are 8 million irrigated acres within the Mississippi Alluvial Plain. The source of most of the irrigated water is the surficial aquifer in the Mississippi Embayment the Mississippi River Valley Alluvial Aquifer (MRVAA) and due to the reliance on irrigation for maximum crop yields recent potentiometric …


Experiencing Extreme Height For The First Time: The Influence Of Height, Self-Judgment Of Fear And A Moving Structural Beam On The Heart Rate And Postural Sway During The Quiet Stance, Mahmoud Habibnezhad, Jay Puckett, M. S. Fardhosseini, Houtan Jebelli, Terry Stentz, L. A. Pratama Jan 2019

Experiencing Extreme Height For The First Time: The Influence Of Height, Self-Judgment Of Fear And A Moving Structural Beam On The Heart Rate And Postural Sway During The Quiet Stance, Mahmoud Habibnezhad, Jay Puckett, M. S. Fardhosseini, Houtan Jebelli, Terry Stentz, L. A. Pratama

Durham School of Architectural Engineering and Construction: Faculty Publications

Falling from elevated surfaces is the main cause of death and injury at construction sites. Based on the Bureau of Labor Statistics (BLS) reports, an average of nearly three workers per day suffer fatal injuries from falling. Studies show that postural instability is the foremost cause of this disproportional falling rate. To study what affects the postural stability of construction workers, we conducted a series of experiments in the virtual reality (VR). Twelve healthy adults—all students at the University of Nebraska-Lincoln—were recruited for this study. During each trial, participants’ heart rates and postural sways were measured as the dependent factors. …


Prediction Of Stress Increase At Ultimate In Unbonded Tendons Using Sparse Principal Component Analysis, Eric Mckinney, Minwoo Chang, Marc Maguire, Yan Sun Jan 2019

Prediction Of Stress Increase At Ultimate In Unbonded Tendons Using Sparse Principal Component Analysis, Eric Mckinney, Minwoo Chang, Marc Maguire, Yan Sun

Durham School of Architectural Engineering and Construction: Faculty Publications

While internal and external unbonded tendons are widely utilized in concrete structures, an analytical solution for the increase in unbonded tendon stress at ultimate strength, ∆fps, is challenging due to the lack of bond between strand and concrete. Moreover, most analysis methods do not provide high correlation due to the limited available test data. The aim of this paper is to use advanced statistical techniques to develop a solution to the unbonded strand stress increase problem, which phenomenological models by themselves have done poorly. In this paper, Principal Component Analysis (PCA), and Sparse Principal Component Analysis (SPCA) …


A Practitioner’S Guide To Small Unmanned Aerial Systems For Bridge Inspection, Sattar Dorafshan, Robert J. Thomas, Calvin Coopmans, Marc Maguire Jan 2019

A Practitioner’S Guide To Small Unmanned Aerial Systems For Bridge Inspection, Sattar Dorafshan, Robert J. Thomas, Calvin Coopmans, Marc Maguire

Durham School of Architectural Engineering and Construction: Faculty Publications

Small unmanned aerial system(s) (sUAS) are rapidly emerging as a practical means of performing bridge inspections. Under the right condition, sUAS assisted inspections can be safer, faster, and less costly than manned inspections. Many Departments of Transportation in the United States are in the early stages of adopting this emerging technology. However, definitive guidelines for the selection of equipment for various types of bridge inspections or for the possible challenges during sUAS assisted inspections are absent. Given the large investments of time and capital associated with deploying a sUAS assisted bridge inspection program, a synthesis of authors experiences will be …


Hvac System Air Filter Diagnostics And Monitoring, Priotomo Abiprojo, Fadi M. Alsaleem Jan 2019

Hvac System Air Filter Diagnostics And Monitoring, Priotomo Abiprojo, Fadi M. Alsaleem

Durham School of Architectural Engineering and Construction: Faculty Publications

A system and method for monitoring a heating, ventilation, or air conditioning (HVAC) system of a building is provided. A monitoring server, located remotely from the building, receives operating parameter data from a monitoring device at the building that measures an operating parameter of the HVAC system. The monitoring server generates a plurality of data clusters from the operating parameter data, each data cluster corresponding to operating parameter data generated during steady-state operation of the HVAC system. The monitoring server calculates an average operating parameter value for each data cluster. The monitoring server calculates normalized operating parameter values based on …


Experimental And Numerical Investigation Of A Novel Adsorption Bed Design For Cooling Applications, Ramy H. Mohammed Jan 2019

Experimental And Numerical Investigation Of A Novel Adsorption Bed Design For Cooling Applications, Ramy H. Mohammed

Electronic Theses and Dissertations

A global challenge is to develop environmentally friendly, affordable, compact and sustainable technologies to provide heating and cooling power. Adsorption cooling (AC) technology is one of the most promising ways to solve the environmental issues and cut down the energy consumption related to the traditional air conditioning and refrigeration systems. However, AC systems still suffer from poor heat and mass transfer inside the adsorption bed, which is the main obstacle to commercialization of adsorption cooling units. The main goal of this study is designing an efficient adsorption cooling cycle. In this research work, an in-depth scaling analysis of heat and …


Ultra-High Performance Concrete For Precast Seismic Bridge Column Connection, Titchenda Chan Jan 2019

Ultra-High Performance Concrete For Precast Seismic Bridge Column Connection, Titchenda Chan

Electronic Theses and Dissertations

Accelerated bridge construction (ABC) utilizes prefabricated bridge elements constructed off-site, delivered, and assembled on-site to expedite construction time and reduce traffic disruption. ABC has been increasingly used for super- and sub-structure elements in low seismic regions. However, its application in medium and high seismic regions remain limited, particularly for precast columns where connections typically coincide with plastic hinge (PH) regions. Ultra-high performance concrete (UHPC), characterized by high compressive and tensile strength, and superior bond properties, is a potential material that can mitigate PH damage and enhance load transfer. This research proposes a new and simple damage tolerant precast column connection …


Broadband Mid-Infrared Frequency Combs Generated Via Frequency Division, Qitian Ru Jan 2019

Broadband Mid-Infrared Frequency Combs Generated Via Frequency Division, Qitian Ru

Electronic Theses and Dissertations

Frequency combs have revolutionized metrology and demonstrated numerous applications in science and technology. Combs operating in the mid-infrared region could be beneficial for molecular spectroscopy for several reasons. First, numerous molecules have their spectroscopic signatures in this region. Furthermore, the atmospheric window (3-5μm and 8-14μm) is located here. Additionally, a mid-infrared frequency comb could be employed as a diagnostic tool for the many components of human breath, as well as for detection of harmful gases and contaminants in the atmosphere. In this thesis, I used synchronously pumped subharmonic optical parametric oscillators (OPOs) operating at degeneracy to produce ultra-broadband outputs near …


Investigation Of Ps-Pvd And Eb-Pvd Thermal Barrier Coatings Over Lifetime Using Synchrotron X-Ray Diffraction, Matthew Northam Jan 2019

Investigation Of Ps-Pvd And Eb-Pvd Thermal Barrier Coatings Over Lifetime Using Synchrotron X-Ray Diffraction, Matthew Northam

Electronic Theses and Dissertations

Extreme operating temperatures within the turbine section of jet engines require sophisticated methods of cooling and material protection. Thermal barrier coatings (TBCs) achieve this through a ceramic coating applied to a substrate material (nickel-based superalloy). Electron-beam physical vapor deposition (EB-PVD) is the industry standard coating used on jet engines. By tailoring the microstructure of an emerging deposition method, Plasma-spray physical vapor deposition (PS-PVD), similar microstructures to that of EB-PVD coatings can be fabricated, allowing the benefits of strain tolerance to be obtained while improving coating deposition times. This work investigates the strain through depth of uncycled and cycled samples using …


Hurricane Imaging Radiometer (Hirad) Tropical Rainfall Retrievals, Abdusalam Alasgah Jan 2019

Hurricane Imaging Radiometer (Hirad) Tropical Rainfall Retrievals, Abdusalam Alasgah

Electronic Theses and Dissertations

The Hurricane Imaging Radiometer (HIRAD) is an airborne passive microwave remote sensor, developed to measure wind speed and rain rate in hurricanes. This dissertation concerns the development of a signal processing algorithm to infer tropical rainfall from HIRAD radiance (brightness temperature, Tb) measurements. The basis of the rain rate retrieval algorithm is an improved forward microwave radiative transfer model (RTM) that incorporates the HIRAD multi-antenna-beam geometry, and uses semi-empirical coefficients derived from an airborne experiment that occurred in the Gulf of Mexico off Tampa Bay in 2013. During this flight, HIRAD observed a squall line of thunderstorms simultaneously with an …


Artificial Magnetism And Topological Phenomena In Optics, Midya Parto Jan 2019

Artificial Magnetism And Topological Phenomena In Optics, Midya Parto

Electronic Theses and Dissertations

Recent years have witnessed intense research activities to effectively control the flow of photons using various classes of optical structures such as photonic crystals and metamaterials. In this regard, optics has benefited from concepts in condensed matter and solid-state physics, where similar problems concerning electronic wavefunctions arise. An important example of such correspondence is associated with the photon dynamics under the effect of an artificial magnetic field. This is especially important since photons, as neutral bosons, do not inherently interact with magnetic fields. One way to mitigate this issue is to exploit magneto-optical materials. However, as is well known, using …


Optical Nanostructures For Controllable And Tunable Optical Properties, Ashfaqul Anwar Anwar Siraji Jan 2019

Optical Nanostructures For Controllable And Tunable Optical Properties, Ashfaqul Anwar Anwar Siraji

Wayne State University Dissertations

Optical nanostructures are heterogeneous media containing subwavelength inclusions in periodic or aperiodic fashion. The optical properties of optical nanostructure can be controlled and tuned using their constituent material properties and spatial arrangement of the inclusions. While optical nanostructures have been widely studied, controllable and tunable nanostructures using low loss transparent materials has not been studied in detail in the literature. The objective of this research is to perform efficient design and analyses of controllable and tunable optical nanostructures using low loss transparent materials.

To that end, versatile and highly accurate numerical methods like finite different tie domain and plane wave …


Distributed Optimal Power And Voltage Management In Dc Microgrids, Eyad A. Sindi Jan 2019

Distributed Optimal Power And Voltage Management In Dc Microgrids, Eyad A. Sindi

Wayne State University Dissertations

The work developed new control strategies to address fundamental issues of power balance, line loss reduction, and voltage profile management in DC microgrids. In microgrids of distributed renewable generations and controllable loads, load allocation to different distributed generators, line losses, voltage stability and quality are intimately coupled, departing significantly from traditional power grids in which economic dispatch and voltage stability are typically separate control tasks.

In this work, a multi-objective optimization strategy is introduced to address the challenges imposed by these coupled issues. Global optimal solutions are derived. Recursive optimization algorithms for distributed control strategies are introduced and shown to …


Development Of A Statistical Model To Predict Australian Flight Students’ Valuation Of Aviation Safety, Michael Chiu, Nickolai Isaksen, Steven Leib Jan 2019

Development Of A Statistical Model To Predict Australian Flight Students’ Valuation Of Aviation Safety, Michael Chiu, Nickolai Isaksen, Steven Leib

Journal of Aviation/Aerospace Education & Research

This study was a quantitative approach to explore whether certain demographic factors, exposure to safety training, flight experience, and engagement could be used to develop a predictive model for how Australian flight students and early career pilots valued safety. Participants were given an online Likert-scale survey to determine their valuation of safety based on SMS safety sub-cultures, safety training, engagement, as well as provided basic demographic metrics including age, flight experience, gender. In addition, a second group of participants representing local Australian culture were given a survey to determine their safety valuation. Linear regression was used to develop the best …


The Effect Of Experiential Education On Pilots' Vfr Into Imc Decision-Making, Geoffrey R. Whitehurst, Lori Brown, William G. Rantz, Dominic Nicolai, Jessica M. Bradley Jan 2019

The Effect Of Experiential Education On Pilots' Vfr Into Imc Decision-Making, Geoffrey R. Whitehurst, Lori Brown, William G. Rantz, Dominic Nicolai, Jessica M. Bradley

Journal of Aviation/Aerospace Education & Research

In aviation, safety is always a primary consideration, and this is especially true during a pilot’s flight training to instill that safety mentality. However, this means that pilots are restricted by safety policies from encountering difficult weather situations during their training, which could, potentially, improve their weather decision-making skills for avoiding future hazardous weather encounters. Thirty-six general aviation pilots of varying instrument flight experience (IF) were allocated, using stratified random sampling based on their IF, to one of three groups, a control group and two educational treatment intervention groups. The educational treatment interventions were designed to improve the participant’s ability …


Comparative Kinetic Modeling Of Growth And Molecular Hydrogen Overproduction By Engineered Strains Of Thermotoga Maritima, Raghuveer Singh, Rahul Tevatia, Derrick White, Yaşar Demirel, Paul H. Blum Jan 2019

Comparative Kinetic Modeling Of Growth And Molecular Hydrogen Overproduction By Engineered Strains Of Thermotoga Maritima, Raghuveer Singh, Rahul Tevatia, Derrick White, Yaşar Demirel, Paul H. Blum

Department of Chemical and Biomolecular Engineering: Faculty Publications

Thermotoga maritima is an anaerobic hyperthermophilic bacterium known for its high amounts of hydrogen (H2) production. In the current study, the kinetic modeling was applied on the engineered strains of T. maritima that surpassed the natural H2 production limit. The study generated a kinetic model explaining H2 overproduction and predicted a continuous fermentation system. A Leudking-Piret equation-based model predicted that H2 production by Tma200 (0.217 mol-H2 g–1-biomass) and Tma100 (0.147 mol-H2 g–1-biomass) were higher than wild type (0.096 mol-H2 g–1 -biomass) with reduced rates of maltose utilization. …