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Articles 601 - 630 of 74973
Full-Text Articles in Engineering
Biomass Demineralization: A Critical Need For Future Biorefineries, Leoncio Santiago-Martínez, Styliani Avraamidou, Alejandro Ayala-Cortés, Ruth Azike, Santanu Bakshi, Chumki Banik, Ezra Bar Ziv, Fei Long, Rebecca Ong, Et Al.
Biomass Demineralization: A Critical Need For Future Biorefineries, Leoncio Santiago-Martínez, Styliani Avraamidou, Alejandro Ayala-Cortés, Ruth Azike, Santanu Bakshi, Chumki Banik, Ezra Bar Ziv, Fei Long, Rebecca Ong, Et Al.
Michigan Tech Publications
Biomass contains up to 14 essential elements that serve as nutrients for plant growth and development, including photosynthesis and enzyme functionalities. These elements in different chemical forms (e.g., minerals) constitute the inorganic fraction of biomass and can cause operational issues in thermal and biochemical biomass conversion technologies. In biomass gasification and pyrolysis processes, for instance, inorganics can cause fouling, tar formation, and corrosion. In catalytic and biochemical processes, inorganics can poison catalysts, alter biochemical pathways, and modify product yields and selectivity. This review provides an overview of the inorganic content in biomass feedstocks, the critical role inorganics play in plant …
Self-Assembly Interactions In Magnetite-Coated Cellulose Nanocrystals: Implications For Magnetic Hyperthermia Applications, Mohammad J. Hasan, Erin L. Mcneill, Kishore Chand, Juganta Roy, Monishita Deb, Katherine Schlaak, Sydney Herzog, Yvonne Sun, Sarah Watzman, Esteban E. Ureña-Benavides, Erick S. Vasquez-Guardado
Self-Assembly Interactions In Magnetite-Coated Cellulose Nanocrystals: Implications For Magnetic Hyperthermia Applications, Mohammad J. Hasan, Erin L. Mcneill, Kishore Chand, Juganta Roy, Monishita Deb, Katherine Schlaak, Sydney Herzog, Yvonne Sun, Sarah Watzman, Esteban E. Ureña-Benavides, Erick S. Vasquez-Guardado
Chemical and Materials Engineering Faculty Publications
Magnetic cellulose nanocrystal (MCNC) nanocomposites are promising sustainable and biocompatible platforms for magnetic hyperthermia; however, the molecular mechanisms governing Fe3O4 adsorption and deposition onto CNCs remain poorly understood. Here, sulfated (S-CNC) and TEMPO-oxidized CNCs (T-CNC) were used to prepare nanocomposites at 1:2 and 1:4 CNC:Fe3O4 mass ratios, enabling a systematic evaluation of how surface chemistry and nanoparticle loading dictate interfacial interactions and magneto-colloidal behavior. Bare magnetite nanoparticles were 21 ± 5 nm by TEM but grew to 144 ± 18 in the DLS measurement at pH 7. The S-CNC nanocomposites had hydrodynamic sizes between 144 and 210 nm, not much …
Evolution Of Polypyrrole Electrode During Electropolymerization And Its Effect On Energy Storage Performance, Duy Pham, Ryan Tcheutchoua Gouafong, Jake Irvin, Ben Mckinney, Jacob Dileonardi, Mason Cox, Ashish Aphale
Evolution Of Polypyrrole Electrode During Electropolymerization And Its Effect On Energy Storage Performance, Duy Pham, Ryan Tcheutchoua Gouafong, Jake Irvin, Ben Mckinney, Jacob Dileonardi, Mason Cox, Ashish Aphale
Faculty Articles
This study investigates the influence of electropolymerization time on the evolution of morphology and the electrochemical performance of polypyrrole (PPy) electrodes. The PPy films were synthesized by varying the deposition time from 300 seconds to 1800 seconds, corresponding to 5 to 50 cycles. The electrodes were characterized by Raman spectroscopy, XPS, and SEM, and electrochemical analyses were conducted using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and galvanostatic charge-discharge (GCD). Experimental results showed that increasing deposition time yields large cauliflower-like structures, thereby enhancing capacitance. The 50 cycle electrode exhibited the highest specific capacitance of 412 F/g in a three-electrode configuration …
Ai Method For Classification Of Diagnosis Of Near-Infrared Breast Lesion Images, Kaiquan Chen, Fangyang Shen, Honggang Wang, Zhengchao Dong, Jizhong Xiao, Ming Ma, Afroza Aktar, Christopher Chow, Wenxiong Zhang
Ai Method For Classification Of Diagnosis Of Near-Infrared Breast Lesion Images, Kaiquan Chen, Fangyang Shen, Honggang Wang, Zhengchao Dong, Jizhong Xiao, Ming Ma, Afroza Aktar, Christopher Chow, Wenxiong Zhang
Publications and Research
In near-infrared optical breast lesion screening and diagnosis systems, high-speed four-dimensional scanners can dynamically acquire tens of thousands of lesion images within a five-minute period. Currently, manual computer annotation is required to generate standard samples from these scanned breast lesion images, a process that depends heavily on physicians with clinical expertise. On average, a single physician can annotate only approximately ten samples per working day. As a result, this process is time-consuming and labor-intensive, and the collected samples often suffer from low accuracy, large variability, and limited diagnostic reliability. Several AI-based annotation tools, such as QuPath, HALO AI™, and X-AnyLabeling, …
Comparative Evaluation Of Segmentation-Based And Pose-Assisted Head Temperature Estimation From Uas Thermal Imagery Under Controlled Conditions, Owais Ahmed, Justin A. Guye, Muhammad Hassan Tanveer, Adeel Khalid
Comparative Evaluation Of Segmentation-Based And Pose-Assisted Head Temperature Estimation From Uas Thermal Imagery Under Controlled Conditions, Owais Ahmed, Justin A. Guye, Muhammad Hassan Tanveer, Adeel Khalid
Faculty Articles
This paper presents a vision-based framework for detecting humans and estimating head surface temperature from aerial thermal imagery acquired by Unmanned Aerial Systems (UAS). A comparative evaluation of recent object detection architectures was conducted to identify the most stable and reliable model for thermal human detection under varying flight altitudes. The selected framework integrates two head localization strategies, namely, segmentation-based mask slicing and pose-assisted keypoint localization, to extract head regions and compute per-pixel temperature values from radiometric metadata. The results show that cross-domain inference using pre-trained YOLOv11 models achieves reliable human detection across controlled outdoor environments. Between the two pipelines, …
Hybrid Thermosetting Polymer Nanocomposite Thin Films With Optimized Thermal Conductivity And Mechanical Reinforcement, Vinicius Alvarenga, Camila M. Maroneze, Matheus S. Dias, Bruno Milton Oliveira Silva, Jaime Taha-Tijerina, Christiano J. S. De Matos, Hélio Ribeiro
Hybrid Thermosetting Polymer Nanocomposite Thin Films With Optimized Thermal Conductivity And Mechanical Reinforcement, Vinicius Alvarenga, Camila M. Maroneze, Matheus S. Dias, Bruno Milton Oliveira Silva, Jaime Taha-Tijerina, Christiano J. S. De Matos, Hélio Ribeiro
Informatics and Engineering Systems Faculty Publications
Epoxy-based thin films reinforced with graphene oxide (GO), hexagonal boron nitride (h-BN), and their hybrid combination (GO/h-BN) at low filler contents (< 1 wt%) were developed to advance thermosetting nanocomposites for high-performance thermal interface materials (TIMs). The incorporation of these 2D nanostructures led to marked and simultaneous increases in both the storage modulus (E′) and the glass transition temperature (Tg) for the individual and hybrid systems. These enhancements indicated strong interfacial interactions between the nanofillers and the epoxy matrix, promoting a more efficient crosslinking density and reinforcing the overall rigidity of the polymer network. Uniform thin films, processed under controlled conditions, exhibited efficient phonon transport without compromising their dielectric integrity, as demonstrated by steady-state and 3-ω thermal analyses. The incorporation of 0.5 wt% GO/h-BN resulted in up to …
Evaluating Square Gradient Theory For Correlation And Prediction Of Surface Tension, J. Richard Elliot
Evaluating Square Gradient Theory For Correlation And Prediction Of Surface Tension, J. Richard Elliot
University Research
The ESD EOS [Elliott, Suresh, and Dohohue, IECR 1990, 29, 1476] is incorporated into the open-source Square Gradient Theory (SGT) library published by Mejia et al. [Mejia, Müller, and Chaparro-Maldonado, J. Chem. Inf. Model. 2021, 61, 1244]. The combined formalism is evaluated for accuracy compared to experimental measurements and empirical correlation methods. Earlier evaluations of the ESD EOS have shown it to provide accuracy like other EOSs for vapor pressure, vapor–liquid, liquid–liquid, and solid–liquid equilibria where the databases covered roughly 500 compounds and 100–200 mixtures each. For surface tension, a database of measured values for roughly 1000 compounds has been …
Sex-Based Effects Of Shock Energy Exposure In Warfighters, Melissa Sutter, Catherine Johnson
Sex-Based Effects Of Shock Energy Exposure In Warfighters, Melissa Sutter, Catherine Johnson
Mining Engineering Faculty Research & Creative Works
Personal armors were initially designed to fit against the male torso, as men previously filled roles requiring them, thus not made to accommodate the female anatomy. As a result, armor worn by female warfighters tends to have non-form fit in the waist, armpit, bust, and collarbone areas, causing reduced coverage. Shifting, riding up, air gaps, breathing difficulty, and physical discomfort have also been observed. Although this has been documented, the impact on the armor's protective capabilities has not been well studied. To address this, this study compared the protective capabilities of unisex armor for male and female warfighters from shock …
Indirect Carbonation Of Fbc Ash For Sustainable Production Of Caco3 And Reactive Pozzolanic Residues, Suhawn Ju, Heejung Jun, Seongho Han, Minseok Kim, Soohyun Song, Mingi Cho, Sukhoon Pyo, Jinyoung Yoon
Indirect Carbonation Of Fbc Ash For Sustainable Production Of Caco3 And Reactive Pozzolanic Residues, Suhawn Ju, Heejung Jun, Seongho Han, Minseok Kim, Soohyun Song, Mingi Cho, Sukhoon Pyo, Jinyoung Yoon
Civil, Architectural and Environmental Engineering Faculty Research & Creative Works
This study investigates the potential of indirect carbonation for CO2 sequestration and high-purity CaCO3 production using fluidized bed combustion (FBC) fly ash (FFA) and bottom ash (FBA). XRF and XRD analyses revealed high reactive CaO contents derived from lime, portlandite, and anhydrite. Calcium extraction using 1- mol NH4Cl achieved markedly higher efficiency than deionized (DI) water, yielding up to 17,586 mg/L of Ca²⁺ and producing 10.2 wt.% and 8.4 wt.% CaCO3 from FFA and FBA, respectively, with CO2 capture capacities of 45.0 and 36.8 kg per ton of ash. The precipitated CaCO3 exhibited …
Mechanisms Of Ventricular Catheter Obstruction, Mohamed Khalil Attie Ms, Christopher Roberts Ms, Carolyn Harris Phd
Mechanisms Of Ventricular Catheter Obstruction, Mohamed Khalil Attie Ms, Christopher Roberts Ms, Carolyn Harris Phd
Medical Student Research Symposium
Background: Hydrocephalus is treated primarily with ventriculoperitoneal shunts, which fail over time mainly due to proximal ventricular catheter (VC) obstruction of the drainage holes. Prior computational fluid dynamics (CFD) studies based on idealized geometries have suggested that cerebrospinal fluid (CSF) preferentially enters distal holes due to lower resistance, thereby increasing the risk of obstruction at those locations. However, these models do not incorporate explanted VC data, patient-specific anatomy, or differences in catheter architecture.
Methods: To evaluate whether flow distribution matches failure sites, we compared obstruction patterns from 30 explanted catheters with CFD simulations of four commercial VC designs. For every …
Using Machine Learning Algorithms To Clarify Relationships Between Soil Properties And Lead Stomach Bioaccessibility, Shehan Wijesinghe, Dibyendu Sarkar, Hadeer Saleh, Khalid Mustafa, Smitha Rao, Rupali Datta
Using Machine Learning Algorithms To Clarify Relationships Between Soil Properties And Lead Stomach Bioaccessibility, Shehan Wijesinghe, Dibyendu Sarkar, Hadeer Saleh, Khalid Mustafa, Smitha Rao, Rupali Datta
Michigan Tech Publications
Featured Application: This paper has important applications in environmental health risk assessment and urban soil remediation planning. By demonstrating how machine learning can predict lead bioaccessibility in lead paint-contaminated soil, the study provides a scalable, cost-effective alternative to laboratory-based extraction methods. Such models could support rapid screening of contaminated sites, helping prioritize high-risk areas for intervention and allocate remediation resources more efficiently. This model is expected to advance data-driven decision-making for managing lead-contaminated soils and protect vulnerable urban populations from exposure. Lead contamination in urban soils, primarily from deteriorating lead-based paint, poses a significant health risk in the United States. …
Online Path Planning For Disaster Response In The Presence Of Unknown Road Disruptions: A Comparison Of Research And Practice, Jannatul Shefa, Ashlea Bennett Milburn, Erica Gralla
Online Path Planning For Disaster Response In The Presence Of Unknown Road Disruptions: A Comparison Of Research And Practice, Jannatul Shefa, Ashlea Bennett Milburn, Erica Gralla
Industrial Engineering Faculty Publications and Presentations
Purpose This paper aims to illuminate gaps between theory and practice in one crucial area of disaster logistics: transportation management between staging areas and final destinations, on uncertain and disrupted road networks. Relevant current practice in federal, state, nonprofit and private disaster response organizations in the USA is described and compared to pertinent assumptions in the literature on disaster response online path planning under uncertainty. Design/methodology/approach The study uses a qualitative approach. The disaster response routing literature informed the development of an interview guide used for in-depth interviews with disaster response logistics practitioners. Collected data were coded to identify how …
Ais26s: Genai And Llms For Cybersecurity, Political Sciences, Transportation Security, And Resiliency, Latifur Khan
Ais26s: Genai And Llms For Cybersecurity, Political Sciences, Transportation Security, And Resiliency, Latifur Khan
Paul English Applied Artificial Intelligence (AI) Institute Publications
This presentation examines the role of generative artificial intelligence (GenAI) and large language models (LLMs) in addressing complex challenges across cybersecurity, political science, and transportation security. Dr. Latifur Khan discusses how advanced AI methods can be applied to threat detection, data analysis, and decision-making in high-risk and data-intensive environments. The talk highlights interdisciplinary applications of LLMs, emphasizing their ability to extract insights from large-scale data, improve system resilience, and support intelligent infrastructure. Emerging research directions and practical implications for real-world deployment are also discussed.
Designing Space-Based Architectures To Discover And Track Hazardous Asteroids Using Mo-Mcts, Adam P. Wilmer, Michael J. Klonowski, Marcus J. Holzinger, Robert A. Bettinger
Designing Space-Based Architectures To Discover And Track Hazardous Asteroids Using Mo-Mcts, Adam P. Wilmer, Michael J. Klonowski, Marcus J. Holzinger, Robert A. Bettinger
Faculty Publications
The discovery and tracking of near-Earth objects (NEOs), such as asteroids and comets, form the foundation of any effective planetary defense mitigation strategy—that is, the process of reducing or eliminating the threat these objects pose to humanity. Establishing sufficient warning time prior to a potential Earth impact is a critical outcome of this capability, as it enables informed decision-making and the selection of viable mitigation options. This study investigates how to optimally pre-position a fleet of NEO discovery and tracking (D&T) spacecraft within the Sun-Earth system. Candidate architectures—one or more pre-positioned spacecraft—are designed using Multi-Objective Monte Carlo Tree Search (MO-MCTS). …
How Q-Succeed-Cny Connects Local Residents To Emerging Semiconductor And Quantum Career Opportunities, Moamer Hasanovic
How Q-Succeed-Cny Connects Local Residents To Emerging Semiconductor And Quantum Career Opportunities, Moamer Hasanovic
SyracuseCoE
This slide deck is from Professor Moamer Hasanovic's talk, "How Q-SUCCEED-CNY Connects Local Residents to Emerging Semiconductor and Quantum Career Opportunities," presented at SyracuseCoE's April 2026 Research & Technology Forum.
An Integrated Tracking Technique For Underwater Navigation Using Acoustic And Imu Measurements, Mainul Islam Chowdhury, Quoc Viet Phung, Iftekhar Ahmed, Daryoush Habibi
An Integrated Tracking Technique For Underwater Navigation Using Acoustic And Imu Measurements, Mainul Islam Chowdhury, Quoc Viet Phung, Iftekhar Ahmed, Daryoush Habibi
Research outputs 2022 to 2026
Accurate navigation is essential for underwater vehicles like AUVs, which often operate in deep or remote areas. However, complex ocean dynamics, cumulative inertial-measurement unit (IMU) drift, and diverse noise sources often result in erratic and unreliable position estimates. To overcome these challenges, we proposed a method that combines underwater acoustic signals with onboard motion sensor data to improve the underwater position tracking system. The proposed system uses a long baseline (LBL) acoustic array of surface buoys to capture the Time-difference-of-Arrival (TDoA) of a multi-pulse beacon. We extract arrival times using a superimposed-envelope-spectrum (SES) detector, which exploits the beacon’s periodic structure …
Corrigendum To “Advanced Techniques In Quartz Wafer Precision Processing: Stealth Dicing Based On Filament-Induced Laser Machining” [Opt. Laser Technol. 171 (2024) 110474] (Optics And Laser Technology (2024) 171, (S0030399223013671), (10.1016/J.Optlastec.2023.110474)), Yun Wang, Yutang Dai, Farhan Mumtaz, Kaiyan Luo
Corrigendum To “Advanced Techniques In Quartz Wafer Precision Processing: Stealth Dicing Based On Filament-Induced Laser Machining” [Opt. Laser Technol. 171 (2024) 110474] (Optics And Laser Technology (2024) 171, (S0030399223013671), (10.1016/J.Optlastec.2023.110474)), Yun Wang, Yutang Dai, Farhan Mumtaz, Kaiyan Luo
Electrical and Computer Engineering Faculty Research & Creative Works
The authors regret, that the affiliation for author Yun Wang was incomplete. To accurately reflect both the author's academic affiliation and the research platform where the work was conducted. The correct affiliation for Yun Wang is updated as above. The authors would like to apologize for any inconvenience caused.
Graphene Synthesis: A Reactor-Oriented Review Of Conventional And Emerging Production Methods, Paul C. Ani, Zeyad Zeitoun, Hasan J. Al-Abedi, Joseph D. Smith
Graphene Synthesis: A Reactor-Oriented Review Of Conventional And Emerging Production Methods, Paul C. Ani, Zeyad Zeitoun, Hasan J. Al-Abedi, Joseph D. Smith
Chemical and Biochemical Engineering Faculty Research & Creative Works
Graphene's unparalleled electrical, mechanical, and thermal properties have positioned it as a transformative material across diverse sectors, including electronics, energy storage, biomedicine, and environmental remediation. However, scalable, cost-effective, and high-quality production remains a critical challenge. This review presents a comprehensive, reactor-oriented analysis of both conventional and emerging graphene synthesis methods, categorized into top-down and bottom-up approaches. Special emphasis is placed on the role of reactor configurations in determining product quality, layer control, scalability, and economic viability. Key synthesis techniques explored include chemical vapor deposition (CVD), epitaxial growth, electrochemical exfoliation, ultrasonic-assisted methods, microwave reactors, combustion synthesis, and plasma-enhanced processes. By evaluating …
Additive Manufacturing Of Ti-Ni Based Ternary Shape Memory Alloys, Yitao Chen, Frank Liou
Additive Manufacturing Of Ti-Ni Based Ternary Shape Memory Alloys, Yitao Chen, Frank Liou
Mechanical and Aerospace Engineering Faculty Research & Creative Works
Metal additive manufacturing has become a powerful tool to develop customized metal alloys and to discover more advanced properties for novel extended applications. Ti-Ni based shape memory alloy is a group of intriguing smart functional materials, and adding a small amount of a third element can promote and induce more attractive functions. Due to the difficulty in traditional processing and the unique feature of material flexibility of in-situ alloying in additive manufacturing processes, not only Ti-Ni binary shape memory alloys but also Ti-Ni-X ternary shape memory alloys can be developed, manufactured, and investigated in-depth by additive manufacturing. This paper provides …
A Model Intercomparison Study To Investigate Mixing Characteristics In Non-Precipitating Stratocumulus Clouds, Fan Yang, Kyoung Ock Choi, Kamal Kant Chandrakar, Fabian Hoffmann, Pei Hou, Steve Krueger, Chunsong Lu, Mikhail Ovchinnikov, Yangze Ren, Shin Ichiro Shima, Peng Wu, Chongzhi Yin, Zeen Zhu, Seong Soo Yum
A Model Intercomparison Study To Investigate Mixing Characteristics In Non-Precipitating Stratocumulus Clouds, Fan Yang, Kyoung Ock Choi, Kamal Kant Chandrakar, Fabian Hoffmann, Pei Hou, Steve Krueger, Chunsong Lu, Mikhail Ovchinnikov, Yangze Ren, Shin Ichiro Shima, Peng Wu, Chongzhi Yin, Zeen Zhu, Seong Soo Yum
Michigan Tech Publications
Recent aircraft observations of marine stratocumulus clouds consistently showed that cloud microphysical relationships vary with altitude, indicating inhomogeneous mixing characteristics near cloud top and homogeneous mixing characteristics in mid-levels of clouds. Here, we conduct model intercomparison of an idealized, non-precipitating stratocumulus cloud to evaluate model consistency and examine whether simulations can reproduce the observed mixing characteristics. The results show that eleven large-eddy simulations with various dynamics and microphysics schemes show good agreement on the thermodynamical, microphysical, and dynamical properties of the stratocumulus-topped boundary layer in a steady state. The inter-model spread in steady-state liquid water path is significantly reduced compared …
Antimicrobial Performance Of Amorphous Vs. Crystalline La1-Xsrxcoo3 Perovskites, S. M. Au Shohag, Fahmida Akhter, Ahmed Touhami, Swati Mohan, Md. Wasikur Rahman, Mohammed Jasim Uddin
Antimicrobial Performance Of Amorphous Vs. Crystalline La1-Xsrxcoo3 Perovskites, S. M. Au Shohag, Fahmida Akhter, Ahmed Touhami, Swati Mohan, Md. Wasikur Rahman, Mohammed Jasim Uddin
Physics & Astronomy Faculty Publications
Perovskite materials, with their unique crystal structure and chemical properties, are emerging as promising antimicrobial agents for potential biomedical applications. In this research, different weight percentages of Sr2 + doped amorphous and crystalline Lanthanum Cobaltite (La1-xSrxCoO3 defined as LSCO) (x = 0, 0.025, 0.05, 0.1, and 0.15) perovskite was synthesized by using a simple combination of sol-gel and molten-salt processes and characterized by X-ray diffraction (XRD), and scanning electron microscopy (SEM) ensures the uniform morphology of the materials. During antimicrobial study using the Kirby Bauer method, amorphous LSCO showed much better activity than crystalline LSCO against Escherichia coli, Vibrio …
Ecovoltaic Solar Energy Development Creates Novel Microclimate, Temperature, And Soil Moisture Patterns Under Solar Panels In A Warm Desert, Juan Pinos, Seth M. Munson, Claire C. Karban, Matthew D. Petrie
Ecovoltaic Solar Energy Development Creates Novel Microclimate, Temperature, And Soil Moisture Patterns Under Solar Panels In A Warm Desert, Juan Pinos, Seth M. Munson, Claire C. Karban, Matthew D. Petrie
Life Sciences Faculty Research
Background As solar energy development expands in desert regions, new installation practices and solar technologies seek to balance ecosystem conservation and energy generation (ecovoltaics). The Gemini Solar Project, a large ecovoltaic facility located in the northeastern Mojave Desert, employed low impact installation methods to reduce disturbance of the desert ecosystem within arrays of bifacial panels mounted on solar tracking systems. We evaluated microclimate and environmental conditions across five locations: four within-facility microsites (underneath solar panels, east and west panel driplines, and interspaces between panel rows) and one in the undisturbed desert outside the facility. Results Under panel microsites experienced lower …
Dendrimer Nanogels With Built-In Free Radical Scavenging Enable Efficient Topical Delivery Of A Hydrophilic Antioxidant To Restore Lens Redox Balance For Cataract Treatment, Lin Qi, Huari Kou, Anna Chernatynskaya, Da Huang, Vimalin Jeyalatha Mani, Humeyra Karacal, Nuran Ercal, Hu Yang
Dendrimer Nanogels With Built-In Free Radical Scavenging Enable Efficient Topical Delivery Of A Hydrophilic Antioxidant To Restore Lens Redox Balance For Cataract Treatment, Lin Qi, Huari Kou, Anna Chernatynskaya, Da Huang, Vimalin Jeyalatha Mani, Humeyra Karacal, Nuran Ercal, Hu Yang
Chemistry Faculty Research & Creative Works
Cataract is a leading cause of vision impairment worldwide and are primarily caused by oxidative stress that damages and aggregates lens proteins, leading to lens opacification. However, the eye's anatomical barriers limit the penetration and bioavailability of antioxidant therapies. To address this challenge, a dendrimer-based nanogel with a built-in reactive oxygen species (ROS)-scavenging capability developed by us was employed to deliver the antioxidant N-acetylcysteine (NAC) to the lens. NAC was loaded into a generation-5 PEGylated poly(amidoamine) dendrimer (G5-PEG-TK, termed the GPT) nanogel. The resulting NAC-GPT was characterized for its ROS-scavenging activity, bioavailability, and corneal permeability. The efficacy of NAC-GPT was …
Matrix-Bound Tenascin-C Directs Neuronal Differentiation Through Stiffness-Tuned Meha Hydrogels Mimicking The Spinal Cord Microenvironment, Rounak Pokharel, Vasanti Dhakate, Jessica Onyak, Elif Ertugral, Chandrasekhar R. Kothapalli, Nic D. Leipzig
Matrix-Bound Tenascin-C Directs Neuronal Differentiation Through Stiffness-Tuned Meha Hydrogels Mimicking The Spinal Cord Microenvironment, Rounak Pokharel, Vasanti Dhakate, Jessica Onyak, Elif Ertugral, Chandrasekhar R. Kothapalli, Nic D. Leipzig
Chemical & Biomedical Engineering Faculty Publications
Spinal cord injury (SCI) leads to a complex remodeling of the extracellular matrix (ECM), where Tenascin-C (TNC) is strongly upregulated during the early phases of the injury cascade. While TNC is known to influence neural cell behavior, its functional role and mode of presentation in guiding neuronal differentiation remains unclear. In this study, we developed a stiffness-controlled methacrylated hyaluronic acid (MeHA) hydrogel platform that mimics the mechanical properties of the spinal cord and enables defined matrix immobilization of TNC. In vivo analyses showed elevated TNC expression from day 1, with the strongest perilesional signal during the subacute period (1 week-1 …
Roadmap On Artificial Intelligence-Augmented Additive Manufacturing, Ali Zolfagharian, Liuchao Jin, Qi Ge, Wei-Hsin Liao, Andrés Díaz Lantada, Francisco Franco Martínez, Tianyu Zhang, Tao Liu, Charlie C.L. Wang, Mohammad Hossein Mosallanejad, Reza Ghanavati, Abdollah Saboori, Alejandro De Blas De Miguel, William Solórzano-Requejo, Yi Cai, Xiangyang Dong, Huangyi Qu, Najmeh Samadiani, Guangyan Huang, Austin Downey, Yanzhou Fu, Lang Yuan
Roadmap On Artificial Intelligence-Augmented Additive Manufacturing, Ali Zolfagharian, Liuchao Jin, Qi Ge, Wei-Hsin Liao, Andrés Díaz Lantada, Francisco Franco Martínez, Tianyu Zhang, Tao Liu, Charlie C.L. Wang, Mohammad Hossein Mosallanejad, Reza Ghanavati, Abdollah Saboori, Alejandro De Blas De Miguel, William Solórzano-Requejo, Yi Cai, Xiangyang Dong, Huangyi Qu, Najmeh Samadiani, Guangyan Huang, Austin Downey, Yanzhou Fu, Lang Yuan
Faculty Publications
Artificial intelligence-augmented additive manufacturing (AI2AM) represents a transformative frontier in digital fabrication, where artificial intelligence (AI) is embedded not as a peripheral tool, but as a central framework driving intelligent, adaptive, and autonomous additive manufacturing (AM) systems. The objective of this Roadmap is to present a comprehensive vision of the state-of-the-art developments in AI2AM while charting the future trajectory of this rapidly emerging field. As AM applications continue to expand across diverse sectors, conventional design and control strategies face growing limitations in scalability, quality assurance, and material complexity. AI uses tools like computer vision, generative design, and large language models …
Guidance For Left-Turn Flashing Yellow Arrow (Fya) Implementation In Nebraska, Aemal Khattak, Li Zhao, Frank Selase Dzawu
Guidance For Left-Turn Flashing Yellow Arrow (Fya) Implementation In Nebraska, Aemal Khattak, Li Zhao, Frank Selase Dzawu
Nebraska Department of Transportation: Research Reports
This research evaluates the safety performance of flashing yellow arrows (FYA) and driver behavioral responses in Nebraska, using data from 324 FYA intersections (Lincoln 160; Omaha 164) to develop evidence-based implementation guidance. The study addresses critical knowledge gaps in local driver acceptance patterns, the effectiveness of phasing configurations, and a comprehensive safety assessment that integrates crash and conflict analyses. The methodology employed four complementary analyses: (1) negative binomial crash frequency modeling of 3945 unique left turn crashes (2015-2024) across Lincoln and Omaha; (2) binary logistic regression of 948 gap acceptance decisions across 43 intersections; (3) linear regression of post-encroachment time …
Update Of Intersection/Interchange Guidelines For Rural Expressways In Nebraska, Aemal Khattak, Mm Shakiul Haque
Update Of Intersection/Interchange Guidelines For Rural Expressways In Nebraska, Aemal Khattak, Mm Shakiul Haque
Nebraska Department of Transportation: Research Reports
Nebraska Department of Transportation (NDOT) staff frequently decide on changes to existing two-way stop- controlled (TWSC) intersections on rural expressway to alternative facilities, such as a restricted crossing U-turn (RCUT), a roundabout, a signalized intersection, or an interchange. As Nebraska makes progress toward completion of its expressway system, updated and defensible decision-making is essential for conversion of TWSC highway intersections. NDOT’s existing guidelines, developed in the 1990s, no longer reflect current operations, safety performance, or modern intersection designs.
This project updated and expanded NDOT’s guidance using contemporary traffic operational and safety data, combined with robust microsimulation and safety performance modeling. …
Ultra-High-Performance Concrete (Uhpc) For Bridge Deck Overlay And Structural Deck Repair, Jiong Hu, George Morcous, Akbota Aitbayeva, Ming Gerges
Ultra-High-Performance Concrete (Uhpc) For Bridge Deck Overlay And Structural Deck Repair, Jiong Hu, George Morcous, Akbota Aitbayeva, Ming Gerges
Nebraska Department of Transportation: Research Reports
Ultra-high-performance concrete (UHPC) is an advanced cementitious material known for its exceptional strength and durability, making it an ideal material for bridge deck overlays and repairs that address the common issue of premature deck deterioration. Conventional UHPC is typically flowable and self-leveling, which makes it unsuitable for deck surfaces with cross-slopes and/or sloped vertical profiles. Therefore, a highly thixotropic UHPC that responds well to vibration while remaining stable on sloped surfaces is needed for overlay applications. Mixtures with varying binder content, water-to-binder ratio, fiber content, and dosages of admixtures were developed and evaluated. Two of the most effective and economical …
An Ultrafine-Resolution Numerical Investigation Of The Influence Of Terrain On Tornado Behavior, Jiamin Dang, Jana Houser, Leigh Orf, Peng Yue, Guirong Yan
An Ultrafine-Resolution Numerical Investigation Of The Influence Of Terrain On Tornado Behavior, Jiamin Dang, Jana Houser, Leigh Orf, Peng Yue, Guirong Yan
Civil, Architectural and Environmental Engineering Faculty Research & Creative Works
This study investigates the effects of idealized and realistic terrain on tornado characteristics and behavior. It uses a novel simulation approach, nesting a high-fidelity, ultrafine-resolution, tornado-scale, engineering large-eddy simulation (LES) within a Cloud Model 1 (CM1) simulation of a tornadic supercell. We analyze the effects of terrain on the tornado's central pressure, horizontal and vertical velocities, vortex shape, and path. Seven idealized terrain configurations are used including 1) a control run with flat ground, 2) and 3) an idealized hill with steep and gradual slopes having the height of 25.4 m, 4) and 5) an idealized escarpment with steep and …
Research Days: Case Study: Creation Of A Student-Driven Radio Talk Show To Answer Cybersecurity Questions And Concerns To Boost Power Skills, Joel Leiva, Anthony Bayate, David Abiandu, Keith Fernandez
Research Days: Case Study: Creation Of A Student-Driven Radio Talk Show To Answer Cybersecurity Questions And Concerns To Boost Power Skills, Joel Leiva, Anthony Bayate, David Abiandu, Keith Fernandez
Center for Cybersecurity
Power skills are essential in any professional career. Oftentimes, college students don’t feel prepared enough to enter the workforce. Having good power skills in a group can greatly increase production and efficiency. This case study aims to develop these power skills in a group of college students through the creation of a student-driven radio talk show answering cybersecurity questions and concerns. A qualitative approach was used via the creation of the C.Y.B.E.R. radio show. This show enhanced the participants’ power skills such as collaboration, teamwork, and communication skills. The findings from this case study prove the alternate hypothesis of boosting …