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Full-Text Articles in Engineering

Dual-Bed Radioiodine Capture From Complex Gas Streams With Zeolites: Regeneration And Reuse Of Primary Sorbent Beds For Sustainable Waste Management, Krista Carlson, Brian J. Riley, Joshua Turner, David C. Cantu, Dev Chidambaram, Charmayne Lonergan, Jeffrey D. Rimer Jan 2025

Dual-Bed Radioiodine Capture From Complex Gas Streams With Zeolites: Regeneration And Reuse Of Primary Sorbent Beds For Sustainable Waste Management, Krista Carlson, Brian J. Riley, Joshua Turner, David C. Cantu, Dev Chidambaram, Charmayne Lonergan, Jeffrey D. Rimer

Materials Science and Engineering Faculty Research & Creative Works

No abstract provided.


Understanding Heterogeneous Nucleation In Iron Alloys From First Principles: A Review And Discussion, Semen Naumovich Lekakh Jan 2025

Understanding Heterogeneous Nucleation In Iron Alloys From First Principles: A Review And Discussion, Semen Naumovich Lekakh

Materials Science and Engineering Faculty Research & Creative Works

Heterogeneous nucleation during solidification plays a key role in structure formation of different types of iron-based alloys, including steels and cast irons. A review summarizes the novel theoretical methods which were used to understand the nature of heterogeneous nucleation in iron-based alloys. An ab initio simulation of atomic adsorption was used to predict the activity of heterogeneous nuclei, and the thermodynamic methods were applied to design conditions for desired precipitate formation in the iron melts. A high-resolution TEM study of individual nucleus and statistics of nuclei family, obtained from an automated SEM/EDX analysis, illustrates a possibility to design processes of …


Designing Robust Quasi-2d Perovskites Thin Films For Stable Light-Emitting Applications, Sharmistha Khan, Reshna Shrestha, Mengru Jin, Doyun Kim, Guan Lin Chen, Ruipeng Li, Yijia Gu, Qing Tu, Namyoung Ahn, Wanyi Nie Jan 2025

Designing Robust Quasi-2d Perovskites Thin Films For Stable Light-Emitting Applications, Sharmistha Khan, Reshna Shrestha, Mengru Jin, Doyun Kim, Guan Lin Chen, Ruipeng Li, Yijia Gu, Qing Tu, Namyoung Ahn, Wanyi Nie

Materials Science and Engineering Faculty Research & Creative Works

Quasi-2D perovskite made with organic spacers co-crystallized with inorganic cesium lead bromide inorganics is demonstrated for near unity photoluminescence quantum yield at room temperature. However, light emitting diodes made with quasi-2D perovskites rapidly degrade which remains a major bottleneck in this field. In this work, It is shown that the bright emission originates from finely tuned multi-component 2D nano-crystalline phases that are thermodynamically unstable. The bright emission is extremely sensitive to external stimuli and the emission quickly dims away upon heating. After a detailed analysis of their optical and morphological properties, the degradation is attributed to 2D phase redistribution associated …


The Effect Of Carbon Equivalent And Nodularity On Multi-Axial Casting Wall Movement During Spheroidal Graphite Iron Solidification And Cooling, Noah J. Brack, Mingzhi Xu, Jingjing Qing, Simon Lekakh Jan 2025

The Effect Of Carbon Equivalent And Nodularity On Multi-Axial Casting Wall Movement During Spheroidal Graphite Iron Solidification And Cooling, Noah J. Brack, Mingzhi Xu, Jingjing Qing, Simon Lekakh

Materials Science and Engineering Faculty Research & Creative Works

Spheroidal graphite iron, also known as ductile iron, is an iron–carbon casting alloy used in industry for its good castability, balanced mechanical properties, and low cost. Ductile iron consists of round graphite nodules in an iron matrix. During solidification and cooling, ductile iron castings experience dynamic volume changes due to the precipitation of graphite nodules and formation of austenite. These dynamic volume changes can distort external casting surfaces, causing swell and shrinkage porosity. A novel apparatus was custom-built to capture the casting wall movement in real time along three axes. This study found that casting expansion increased with carbon equivalent …


Controlling Nitrogen Pickup During Induction Melting Of Ultrahigh-Strength Cr-Ni-Mo-V Steels, Kingsley T. Amatanweze, Viraj A. Athavale, Mario F. Buchely, Laura N. Bartlett, Ronald J. O'Malley, Daniel M. Field Jan 2025

Controlling Nitrogen Pickup During Induction Melting Of Ultrahigh-Strength Cr-Ni-Mo-V Steels, Kingsley T. Amatanweze, Viraj A. Athavale, Mario F. Buchely, Laura N. Bartlett, Ronald J. O'Malley, Daniel M. Field

Materials Science and Engineering Faculty Research & Creative Works

Nitrogen pickup during air induction melting can result in porosity and a loss of fracture toughness in ultrahigh-strength quenched and tempered steel castings. Nitrogen atoms are easily adsorbed into liquid steel upon exposure to the air, and argon shrouding alone has limited effectiveness. Previous studies have shown that proper charge sequencing and maintaining a high amount of dissolved oxygen in the melt prior to tapping and deoxidation can limit nitrogen pickup in the melt. In the current study, the effect of melt practice and charging procedure on nitrogen pickup was studied as a function of hold time in a series …


Parametric Analysis Of Water Jet Descaling Efficiency Of Reheated Continuously Cast Thin Slab, Tochukwu P. Ojiako, Mario F. Buchely, Simon Lekakh, Ronald J. O'Malley, Richard Osei, Taha Tayebali Jan 2025

Parametric Analysis Of Water Jet Descaling Efficiency Of Reheated Continuously Cast Thin Slab, Tochukwu P. Ojiako, Mario F. Buchely, Simon Lekakh, Ronald J. O'Malley, Richard Osei, Taha Tayebali

Materials Science and Engineering Faculty Research & Creative Works

Efficient oxide scale removal is critical for maintaining surface quality and process efficiency in steel manufacturing. This study optimizes water jet descaling by evaluating the performance of flat and rotary jet nozzles under varying process parameters. Using a combined approach of experimental analysis and computational fluid dynamics, it investigates the influence of pressure (138–275 bar), lead angle (0°, 15°, 25°), working distance (50–100 mm), and spray angle (15°–25°) on descaling efficiency. Findings indicate that flat jet nozzles achieve superior performance at short working distances due to concentrated impact forces, while rotary jet nozzles sustain efficiency over extended distances through dynamic …


A Novel Technique For Improved Measurement Of Graphite And Inclusions In Ductile Iron Contaminated By Boron, Chase Schroeder, Colleen Lehrer, Simon Lekakh, Laura Bartlett Jan 2025

A Novel Technique For Improved Measurement Of Graphite And Inclusions In Ductile Iron Contaminated By Boron, Chase Schroeder, Colleen Lehrer, Simon Lekakh, Laura Bartlett

Materials Science and Engineering Faculty Research & Creative Works

The highly heterogeneous microstructure of ductile iron in casting includes graphite particles, non-metallic inclusions, microporosity, and other features, such as carbides distributed in the ferrite–pearlite matrix. Determination and comprehensive quantification of microstructural features are practically important however challenging. An advanced methodology based on an automated SEM/EDX analysis was developed and compared to the standard optical imaging method. In addition to backscattered electron contrast, sensitive to atomic number, a novel methodology added EDX data to identify and classify the multiple structural features at micron resolution thresholding. To quantify the shape of individual phases, the eight chord raster algorithms was used and …


Effect Of Gating Design On Filling And Inclusion Control In An Al-Killed Cr-Mo-Ni Steel, Kingsley T. Amatanweze, Koushik Balasubramanian, Soumava Chakraborty, Viraj A. Athavale, Mario F. Buchely, Laura N. Bartlett, Ronald J. O'Malley, Daniel M. Field, Krista R. Limmer, Katherine M. Sebeck Jan 2025

Effect Of Gating Design On Filling And Inclusion Control In An Al-Killed Cr-Mo-Ni Steel, Kingsley T. Amatanweze, Koushik Balasubramanian, Soumava Chakraborty, Viraj A. Athavale, Mario F. Buchely, Laura N. Bartlett, Ronald J. O'Malley, Daniel M. Field, Krista R. Limmer, Katherine M. Sebeck

Materials Science and Engineering Faculty Research & Creative Works

The effect of gating system design on the inclusion population and size distribution in an aluminum-killed low-alloy advanced high strength steel casting was studied. A mold with four different gating systems: pressurized and non-pressurized with side risers, naturally pressurized with a side riser, and naturally pressurized with a top riser, was designed using computational fluid dynamics and solidification software. The design allowed inclusion populations in castings produced with each gating system to be compared during the same pouring event. Samples taken from different positions just below the top surface of each casting were analyzed using an SEM/EDS system with automated …


Ultrafast Belite (Β-C2s) Production Using Biofuel-Based Combustion Synthesis, Shubham Agrawal, Sayee Srikarah Volaity, Oluwadamilare Charles Adesina, Bryan K. Aylas-Paredes, Taihao Han, Srinivas Kilambi, Aditya Kumar, Narayanan Neithalath Jan 2025

Ultrafast Belite (Β-C2s) Production Using Biofuel-Based Combustion Synthesis, Shubham Agrawal, Sayee Srikarah Volaity, Oluwadamilare Charles Adesina, Bryan K. Aylas-Paredes, Taihao Han, Srinivas Kilambi, Aditya Kumar, Narayanan Neithalath

Materials Science and Engineering Faculty Research & Creative Works

This study presents a novel low-temperature, combustion synthesis (CS) approach for the rapid production of belite-rich cements. CS leverages the exothermic heat released from the combustion of biofuels such as lignin and/or biomass, intermixed with pelletized limestone and quartz. At an imposed furnace temperature of ∼700°C (as opposed to 1200°C–1300°C required in a conventional kiln), the source materials are rapidly transformed to belite, resulting in energy, emissions, and economic benefits. This work explores the influence of various process parameters, viz., fuel types and contents, airflow rate, porosity, holding temperature, and holding time on the efficiency of CS-based belite synthesis. Through …


Roadmap To 100 Gwdc: Scientific And Supply Chain Challenges For Cdte Photovoltaics, B. Edward Sartor, Samantha B. Reese, Lorelle M. Mansfield, Ryan Muzzio, Chun Sheng Jiang, Eric Colegrove, John S. Mangum, Camden L. Kasik, Daniel Z. Shaw, James R. Sites, Ramesh G. Dhere, Alex B. Goldstone, Michael S. Moats Jan 2025

Roadmap To 100 Gwdc: Scientific And Supply Chain Challenges For Cdte Photovoltaics, B. Edward Sartor, Samantha B. Reese, Lorelle M. Mansfield, Ryan Muzzio, Chun Sheng Jiang, Eric Colegrove, John S. Mangum, Camden L. Kasik, Daniel Z. Shaw, James R. Sites, Ramesh G. Dhere, Alex B. Goldstone, Michael S. Moats

Materials Science and Engineering Faculty Research & Creative Works

This roadmap highlights pathways to expand the CdTe module manufacturing capacity per year to 100 GWDC by 2030 by improving Te extraction from existing supply chains, minimizing Te usage in modules by leveraging thinner absorbers, and focusing research efforts in key areas to improve module efficiencies. Both scientific and supply chain innovations will be necessary to maintain the high compound annual growth rate of the CdTe photovoltaic (PV) industry and cement its role as a key technology for multi-TW-scale PV deployment.


Hydrogen Permeation In Iron-Chromium-Aluminum (Fecral) Alloys And The Effects Of Microstructure And Surface Oxide, Nathan T. Gehmlich, Thomas F. Fuerst, Hanns Gietl, Chase N. Taylor, Joshua Rittenhouse, Haiming Wen, M. Nedim Cinbiz Jan 2025

Hydrogen Permeation In Iron-Chromium-Aluminum (Fecral) Alloys And The Effects Of Microstructure And Surface Oxide, Nathan T. Gehmlich, Thomas F. Fuerst, Hanns Gietl, Chase N. Taylor, Joshua Rittenhouse, Haiming Wen, M. Nedim Cinbiz

Materials Science and Engineering Faculty Research & Creative Works

Iron–chromium–aluminum (FeCrAl) class alloys are candidates for use as cladding for accident-tolerant fuels and moderators. In this context, hydrogen isotope permeation in FeCrAl alloys is an important material property. In the present work, the apparent permeability, effective diffusivity, and apparent solubility of hydrogen in the FeCrAl alloys C26M and Kanthal D (KD) were measured with gas-driven hydrogen permeation. Permeation measurements were conducted at temperatures of 400 to 700 °C and at gas-driven pressures from 1 to 100 kPa. In particular, the effect of grain size on hydrogen transport was studied with KD samples with three different microstructures: nanocrystalline (NC), ultra-fine …


Quality Improvement Of Polycarbonate Medical Device By Moldex3d And Taguchi Doe, Upoma Saha, Wael Mokhtar Jan 2025

Quality Improvement Of Polycarbonate Medical Device By Moldex3d And Taguchi Doe, Upoma Saha, Wael Mokhtar

Open Access Publishing Support Funded Articles

Incorporating a new design combined with a thermoplastic material without having a prior process database may cause numerous defects in the molded part. Along with the initial setup cost, the scrape due to defects can add additional costs to the production. To address such issues, the numerical analysis tool Moldex3D was used to conduct simulations, and Taguchi Design of Experiment (DOE) was performed to optimize the process parameters. For this study, a classic medical device like the safety goggle model has been chosen as a subject. An amorphous material, polycarbonate, was used because of its transparent and significant thermal properties. …


Optimal Control Of Queueing Systems With Error-Prone Servers, Junqi Hu, Sigrún Andradóttir, Hayriye Ayhan Jan 2025

Optimal Control Of Queueing Systems With Error-Prone Servers, Junqi Hu, Sigrún Andradóttir, Hayriye Ayhan

Information Technology & Decision Sciences Faculty Publications

Consider a Markovian tandem line with finite intermediate buffers and an equal number of stations and servers. Servers are flexible but noncollaborative, so that a job can be processed by at most one server at any time. When a job is being processed, it can be damaged and wasted depending on the proficiency of the server. We identify the dynamic server assignment policy that maximizes the long-run average throughput of the system with two stations and two servers. We find that the optimal policy is either a single or a double threshold policy on the number of jobs in the …


Agency, Index & Process: Investigating The Role Of The Artist’S Body In Digital Sculpture Production, Alan Magee Jan 2025

Agency, Index & Process: Investigating The Role Of The Artist’S Body In Digital Sculpture Production, Alan Magee

Doctoral

Contemporary Digital Sculpture has emerged out of recent developments in digital art, 3d modelling and virtual modes of production. These advances range from the creation of more powerful software and hardware systems to the to nascent XR sectors, and the potential for materialisation through technologies such as 3d printing, laser-cutting, or CNC1 machining. However, critical discourse remains predominantly focused on the end product, often overlooking the embodied labour processes inherent in its creation. As revealed through indexical traces of the artist’s body, these processes encapsulate the gestures, actions and subjective agency of artistic activity. Consequently, with the limitations of digital …


Comparison Of Laboratory Scale Bourbon Whiskey Mashing And Fermentation To Pilot Scale, Ryan C. Sarhan, Brad J. Berron, Czarena L. Crofcheck, Glenna Joyce Welsko, Tyler J. Barzee Jan 2025

Comparison Of Laboratory Scale Bourbon Whiskey Mashing And Fermentation To Pilot Scale, Ryan C. Sarhan, Brad J. Berron, Czarena L. Crofcheck, Glenna Joyce Welsko, Tyler J. Barzee

Biosystems and Agricultural Engineering Faculty Publications

Why the work was done: Laboratory scale methods are useful for optimising grain spirit production. While small scale methods exist, comparisons between conventional, simultaneous saccharification and fermentation, and distillery scale production are lacking. Further, there is limited understanding of how these methods affect the rheological properties of the mash and flavour compounds from fermentation. This study compared conventional and simultaneous saccharification and fermentation mashing methods to a pilot scale distillery to establish a standard laboratory method for simulating industrial bourbon production.

How the work was done: Two mashing methods for bourbon whiskey were compared: simultaneous saccharification and fermentation versus conventional …


Contaminant Mixtures And Their Impact On Nitrate Removal In Wetlands: A Mesocosm Study, Emily N. Byers, Tiffany L. Messer, Daniel N. Miller, Christopher Barton, Jason M. Unrine, Carmen Agouridis Jan 2025

Contaminant Mixtures And Their Impact On Nitrate Removal In Wetlands: A Mesocosm Study, Emily N. Byers, Tiffany L. Messer, Daniel N. Miller, Christopher Barton, Jason M. Unrine, Carmen Agouridis

Biosystems and Agricultural Engineering Faculty Publications

Constructed wetlands are used extensively to mitigate surface runoff. While wetland treatment for nitrogen (N) has been comprehensively studied, a knowledge gap remains regarding the implications of other contaminants (e.g., pesticides, pharmaceuticals) on nitrate-N (NO3-N) removal. This study sought to fill that gap by determining the impact imidacloprid, caffeine, perfluorooctane sulfonic acid (PFOS), atrazine, glyphosate, and sulfate (SO42−) have on NO3-N removal rates. The contaminants were determined based on their occurrence across Kentucky surface waters in urban (imidacloprid, caffeine, and PFOS) and rural (atrazine, glyphosate, and SO42−) environments. Two constructed …


A Pyrrole Modified 3,4-Propylenedioxythiophene Conjugated Polymer As Hole Transport Layer For Efficient And Stable Perovskite Solar Cells, Yuanhao Tang, Ke Ma, Wenhao Shao, Yoon Ho Lee, Ashkan Abtahi, Jiaonan Sun, Hanjun Yang, Aidan H. Coffey, Harindi R. Atapattu, Mustafa Ahmed, Qixuan Hu, Wenzhan Xu, Raunak Dani, Limei Wang, Chenhui Zhu, Kenneth R. Graham, Jianguo Mei, Letian Dou Jan 2025

A Pyrrole Modified 3,4-Propylenedioxythiophene Conjugated Polymer As Hole Transport Layer For Efficient And Stable Perovskite Solar Cells, Yuanhao Tang, Ke Ma, Wenhao Shao, Yoon Ho Lee, Ashkan Abtahi, Jiaonan Sun, Hanjun Yang, Aidan H. Coffey, Harindi R. Atapattu, Mustafa Ahmed, Qixuan Hu, Wenzhan Xu, Raunak Dani, Limei Wang, Chenhui Zhu, Kenneth R. Graham, Jianguo Mei, Letian Dou

Chemical and Materials Engineering Faculty Publications

Despite the outstanding electric properties and cost-effectiveness of poly- (3,4-ethylenedioxythiophene) (PEDOT) and its derivatives, their performance as hole transport layer (HTL) materials in conventional perovskite solar cells (PSCs) has lagged behind that of widely used spirobifluorene-based molecules or poly(triaryl amine). This gap is mainly from their poor solubility and energy alignment mismatch. In this work, the design and synthesis of a pyrrole-modified HTL (PPr) based on 3,4-propylenedioxythiophene (ProDOT) are presented for efficient and stable PSCs. As a result of the superior defects passivation ability, excellent contact with perovskite, enhanced hole extraction, and high hydrophobicity, the unencapsulated PPr-based PSCs showed the …


Analysis Of Tar And Oil Derived From Pyrolysis And Copyrolysis Of Waste Plastics And Biomass, Anitha Shankaralinge Gowda, Dimitrios Karadimas, Jeffrey Seay Jan 2025

Analysis Of Tar And Oil Derived From Pyrolysis And Copyrolysis Of Waste Plastics And Biomass, Anitha Shankaralinge Gowda, Dimitrios Karadimas, Jeffrey Seay

Chemical and Materials Engineering Faculty Publications

Pyrolysis has been proposed as a potential technology for managing the growing volume of plastic waste generated worldwide. Co-pyrolysis of plastic waste with biomass is a promising technology for generating fuel and chemical products. However, this process generates tar as a waste product. The chemical properties of this tar have yet to be thoroughly analyzed. This study presents the results of gas chromatography–mass spectrometry (GC–MS), Fourier-transform infrared spectroscopy (FTIR), and thermogravimetric analysis (TGA) of oil and tar obtained from the pyrolysis of pure plastics including high-density polyethylene (HDPE), low-density polyethylene (LDPE), polyethylene (PE), polystyrene (PS), and plastic-biomass mixtures. GC–MS analysis …


Membrane Filtration Of Nanoscale Biomaterials: Model System And Membrane Performance Evaluation For Aav2 Viral Vector Clarification And Recovery, Mara Leach, Kearstin Edmonds, Emily Ingram, Rebecca E. Dutch, Ranil Wickramasinghe, Malgorzata Chwatko, Dibakar Bhattacharyya Jan 2025

Membrane Filtration Of Nanoscale Biomaterials: Model System And Membrane Performance Evaluation For Aav2 Viral Vector Clarification And Recovery, Mara Leach, Kearstin Edmonds, Emily Ingram, Rebecca E. Dutch, Ranil Wickramasinghe, Malgorzata Chwatko, Dibakar Bhattacharyya

Chemical and Materials Engineering Faculty Publications

The growing demand for viral vectors as nanoscale therapeutic agents in gene therapy necessitates efficient and scalable purification methods. This study examined the role of nanoscale biomaterials in optimizing viral vector clarification through a model system mimicking real AAV2 crude harvest material. Using lysed HEK293 cells and silica nanoparticles (20 nm) as surrogates for AAV2 crude harvest, we evaluated primary (depth filters) and secondary (membrane-based) filtration processes under different process parameters and solution conditions. These filtration systems were then assessed for their ability to recover nanoscale viral vectors while reducing DNA (without the need for endonuclease treatment), protein, and turbidity. …


Fundamental And Application Of Co-Assembly Of Peptides And Proteins: Experiment And Computation, Newton A. Ihoeghian, Qing Shao Jan 2025

Fundamental And Application Of Co-Assembly Of Peptides And Proteins: Experiment And Computation, Newton A. Ihoeghian, Qing Shao

Chemical and Materials Engineering Faculty Publications

Peptides and proteins can co-assemble into various nanostructures based on complementary non-covalent interactions such as electrostatic forces, hydrogen bonding, and hydrophobic associations. These co-assemblies create a design space of functional materials for a wide spectrum of energy, environmental, and biomedical applications. This review focuses on the fundamentals and applications of three co-assembling systems: ultra-short peptides, peptides, and proteins. We will present and discuss experimental studies demonstrating applications in drug delivery, tissue engineering, and biomaterials development. We will also discuss the contribution of computational research, including molecular dynamics simulations and machine learning, to enhance our understanding of assembly mechanisms. Integrating experimental …


Advances In Magnetic Nanoparticles For Molecular Medicine, Xiaoyue Yang, Sarah E. Kubican, Zhongchao Yi, Sheng Tong Jan 2025

Advances In Magnetic Nanoparticles For Molecular Medicine, Xiaoyue Yang, Sarah E. Kubican, Zhongchao Yi, Sheng Tong

Biomedical Engineering Faculty Publications

Magnetic nanoparticles (MNPs) are highly versatile nanomaterials in nanomedicine, owing to their diverse magnetic properties, which can be tailored through variations in size, shape, composition, and exposure to inductive magnetic fields. Over four decades of research have led to the clinical approval or ongoing trials of several MNP formulations, fueling continued innovation. Beyond traditional applications in drug delivery, imaging, and cancer hyperthermia, MNPs have increasingly advanced into molecular medicine. Under external magnetic fields, MNPs can generate mechano- or thermal stimuli to modulate individual molecules or cells deep within tissue, offering precise, remote control of biological processes at cellular and molecular …


Clinical Correlation Of Sars-Cov-2 Wastewater Passive Sampling In Long-Term Care Facilities And Wastewater Treatment Plants, William Strike, Alexus Lori Rockward, Blazan Mijatovic, Ann Noble, Cullen Olsson, Soroosh Torabi, Mohammad Dehghan Banadaki, Reuben Adatorwovor, James W. Keck, Scott M. Berry Jan 2025

Clinical Correlation Of Sars-Cov-2 Wastewater Passive Sampling In Long-Term Care Facilities And Wastewater Treatment Plants, William Strike, Alexus Lori Rockward, Blazan Mijatovic, Ann Noble, Cullen Olsson, Soroosh Torabi, Mohammad Dehghan Banadaki, Reuben Adatorwovor, James W. Keck, Scott M. Berry

Biomedical Engineering Faculty Publications

Wastewater-based epidemiology (WBE) is a promising tool for improving health outcomes through early detection and cost-effective pathogen surveillance. Long-term care facilities (LTCFs) serve and employ vulnerable populations that may particularly benefit from the use of WBE, but financial and technical costs associated with standard sampling methods limit the feasibility of WBE in the LTCF setting. In this work, we used passive sampling to simplify the wastewater analysis process and compared its performance to the standard composite sampling method. Moore swabs and automatic composite samplers were used concurrently to sample wastewater from two LTCFs, and samples were analyzed for SARS-CoV-2 concentration. …


Affordable Miniaturized Speckle Contrast Diffuse Correlation Tomography Device For Depth-Sensitive Mapping Of Cerebral Blood Flow In Rodents, Fatemeh Hamedi, Faezeh Akbari, Mehrana Mohtasebi, Chong Huang, Li Chen, Lei Chen, Guoqiang Yu Jan 2025

Affordable Miniaturized Speckle Contrast Diffuse Correlation Tomography Device For Depth-Sensitive Mapping Of Cerebral Blood Flow In Rodents, Fatemeh Hamedi, Faezeh Akbari, Mehrana Mohtasebi, Chong Huang, Li Chen, Lei Chen, Guoqiang Yu

Biomedical Engineering Faculty Publications

Significance: Continuous and longitudinal monitoring of cerebral blood flow (CBF) is critical for understanding brain pathophysiology and guiding interventions. Although rodents are the primary models in neuroscience, existing imaging modalities often fail to provide the optimal combination of low cost, high spatiotemporal resolution, wide head coverage, and sufficient penetration depth for small-animal brain imaging.

Aim: Leveraging a clinical speckle contrast diffuse correlation tomography (scDCT) system, we aimed to develop an affordable, user-friendly, fast, and miniaturized scDCT (mini-scDCT) device tailored for depth-sensitive CBF imaging in small rodents.

Approach: The mini-scDCT replaces bulky and costly optoelectronic components with compact, low-cost alternatives while …


Implementing Wastewater-Based Epidemiology For Long-Read Metagenomic Sequencing Of Antimicrobial Resistance In Kampala, Uganda, William Strike, Temitope O. C. Faleye, Brian Lubega, Alexus Lori Rockward, Soroosh Torabi Jan 2025

Implementing Wastewater-Based Epidemiology For Long-Read Metagenomic Sequencing Of Antimicrobial Resistance In Kampala, Uganda, William Strike, Temitope O. C. Faleye, Brian Lubega, Alexus Lori Rockward, Soroosh Torabi

Biomedical Engineering Faculty Publications

Antimicrobial resistance (AMR) is an emerging global threat that is expanding in many areas of the world. Wastewater-based epidemiology (WBE) is uniquely suited for use in areas of the world where clinical surveillance is limited or logistically slow to identify emerging threats, such as in Sub-Saharan Africa (SSA). Wastewater was analyzed from three urban areas of Kampala, including a local HIV research clinic and two informal settlements. Wastewater extraction was performed using a low-cost, magnetic bead-based protocol that minimizes consumable plastic consumption followed by sequencing on the Oxford Nanopore Technology MinION platform. The majority of the analysis was performed using …


Thermal Management For Optimal Performance Of Polymer Electrolyte Membrane Unitized Regenerative Fuel Cells, Mythy Tran, Ayodeji Demuren Jan 2025

Thermal Management For Optimal Performance Of Polymer Electrolyte Membrane Unitized Regenerative Fuel Cells, Mythy Tran, Ayodeji Demuren

Mechanical & Aerospace Engineering Faculty Publications

Hydrogen is an excellent carrier for energy storage and can be produced from various green and renewable sources. However, the cost of producing hydrogen and converting it to useful energy is much higher than fossil fuel and traditional energy generation and storage systems. Unitized regenerative fuel cells (URFC) maximize utilization of high-cost cells and their components, thus, lowering system capital cost. Improving the URFC efficiency is an effective way to lower its operating cost. This study evaluates utilization of waste heat during operation and recovery strategy to improve system efficiency of Proton Exchange Membrane (PEM) URFC. A COMSOL Multiphysics 3-D …


Transforming Engineering Education: Project-Based Learning And Technology Integration In A Senior-Level Mechanisms Course, Krishnanand Kaipa, Anurag Purwar, Orlando M. Ayala, Sebastian Bawab Jan 2025

Transforming Engineering Education: Project-Based Learning And Technology Integration In A Senior-Level Mechanisms Course, Krishnanand Kaipa, Anurag Purwar, Orlando M. Ayala, Sebastian Bawab

Mechanical & Aerospace Engineering Faculty Publications

Engineering education faces the challenge of preparing students for a rapidly evolving, interdisciplinary field that demands a strong foundation in theoretical principles, practical skills, and the ability to solve real-world problems. This study describes a project-based learning (PBL) intervention implemented in a senior-level mechanical engineering course focused on mechanisms analysis and design. The intervention combined foundational coursework with bio-inspired design projects, where students developed walking end-effector robotic mechanisms for medical applications. Students utilized tools such as MotionGen software and SnappyXO kits to synthesize, simulate, prototype, and test their designs. Qualitative analysis of student evaluations and project reports revealed that the …


Wip-Monarch Accelerator Program To Engineering: A Reflection On The First Semester, Kristin Eden, Jeffrey W. Fergus, Stacie I. Ringleb Jan 2025

Wip-Monarch Accelerator Program To Engineering: A Reflection On The First Semester, Kristin Eden, Jeffrey W. Fergus, Stacie I. Ringleb

Mechanical & Aerospace Engineering Faculty Publications

This work in progress paper examines the Monarch Accelerator Program to Engineering (MAP2E) program. The MAP2E Program was developed to assist students who desire to become engineers but may need additional assistance in math and science. and it allows students to develop their math and science skills while creating a pathway to personal or professional enriching skills. Furthermore, the MAP2E program allows students to develop their math and science skills and create parallel pathways to personal or professionally enriching skills. For instance, a student may hope to one day start their own engineering firm. A business administration pathway would allow …


Optimal Control And Structurally-Informed Gradient Optimization Of A Custom 4-Dof Rigid-Body, Brock Marcinczyk, Logan E. Beaver Jan 2025

Optimal Control And Structurally-Informed Gradient Optimization Of A Custom 4-Dof Rigid-Body, Brock Marcinczyk, Logan E. Beaver

Mechanical & Aerospace Engineering Faculty Publications

This work develops a control-centric framework for a custom 4-DOF rigid-body manipulator by coupling a reduced-order Pontryagin’s Maximum Principle (PMP) controller with a physics-informed Gradient Descent stage. The reduced PMP model provides a closed-form optimal control law for the joint accelerations, while the Gradient Descent module determines the corresponding time horizons by minimizing a cost functional built directly from the full Rigid-Body Dynamics. Structural-mechanics reaction analysis is used only to initialize feasible joint velocities—most critically the azimuthal component—ensuring that the optimizer begins in a physically admissible region. The resulting kinematic trajectories and dynamically consistent time horizons are then supplied to …


Enhancing Risk And Crisis Communication With Computational Methods: A Systematic Literature Review, Madison H. Munro, Ross J. Gore, Christopher J. Lynch, Yvette D. Hastings, Ann Marie Reinhold Jan 2025

Enhancing Risk And Crisis Communication With Computational Methods: A Systematic Literature Review, Madison H. Munro, Ross J. Gore, Christopher J. Lynch, Yvette D. Hastings, Ann Marie Reinhold

VMASC Publications

Recent developments in risk and crisis communication (RCC) research combine social science theory and data science tools to construct effective risk messages efficiently. However, current systematic literature reviews (SLRs) on RCC primarily focus on computationally assessing message efficacy as opposed to message efficiency. We conduct an SLR to highlight any current computational methods that improve message construction efficacy and efficiency. We found that most RCC research focuses on using theoretical frameworks and computational methods to analyze or classify message elements that improve efficacy. For improving message efficiency, computational and manual methods are only used in message classification. Specifying the computational …


Applying Transfer Learning For Street-Scale Nuisance Flood Forecasting In Coastal-Urban Cities, Binata Roy, Jonathan L. Goodall, Diana Mcspadden, Chetan Kumar, Steven Goldenberg, Yidi Wang, Malachi Schram Jan 2025

Applying Transfer Learning For Street-Scale Nuisance Flood Forecasting In Coastal-Urban Cities, Binata Roy, Jonathan L. Goodall, Diana Mcspadden, Chetan Kumar, Steven Goldenberg, Yidi Wang, Malachi Schram

VMASC Publications

An important challenge with Machine Learning (ML) is its transferability; i.e., whether a ML model trained on one set of data can be applied to a second set of data without requiring full re-training of the model. Transfer Learning (TL) addresses this challenge by transferring knowledge learned in the source domain (the data it was trained on) to the target domain (a second set of data that is statistically different but related, which the model was not trained on). This study investigates the use of TL for street-scale nuisance flood forecasting by exploring whether a ML model trained for one …