Mechanical Engineering Commons^™

Liposomal Uptake Of Silver And Gold Nanoparticles, Dipon Chanda

LSU Master's Theses

The main objective of this work is to study the liposomal uptake of silver and old nanoparticles. Liposomes were prepared in Heating Method. The phospholipids used to prepare liposomes are 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (16:0 PC); 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 PG); 1,2-distearoyl-sn-glycero-3-phosphocholine (18:0 PC); 1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (18:0 PG).Four different combinations of phospholipids were used to prepare liposomes. In all four combinations two types of phospholipids were used. The liposomes were incubated for 30 minute, 1 hour, 2 hour and 4 hour with silver and gold nanoparticles in streptavidin coated glass slide. All four liposomal formulations had a biotinylated lipid (1-oleoyl-2-[12-biotinyl(aminododecanoyl)]-sn-glycero-3-phosphocholine) which has a string …

Development Of A Laboratory Scale Reactor Facility To Generate Hydrogen Rich Syngas Via Thermochemical Energy Conversion, Mandeep Sharma

LSU Master's Theses

The thesis provides data needed for development of a conical spouted bed (CSB) reactor for the purpose of producing hydrogen rich synthesis gas (syngas). The syngas has potential to utilize energy more efficiently, eliminate pollutant emissions and significantly cut emissions of greenhouse gases. The development of CSB reactor system involves three phases. The first phase investigates the hydrodynamic behavior of a small, laboratory scale, conical spouted bed (CSB) by considering the effect of specific system parameters (stagnated bed height, particle size and inlet diameter) on minimum spouting velocity (ums)o, stable operating pressure drop (∆Pms) and maximum pressure drop (∆PM). Experimental …

Parametric Optimization Of A Single-Tracked Vehicle, Darrick Jason Berner

LSU Master's Theses

ABSTRACT The purpose of a suspension system for a vehicle is to contribute to the handling and assist in isolating the occupants from vibrations due to road irregularities. Generally, these primary functions are often at odds so the goal is to design a suspension system that finds the appropriate compromise. The focus of this thesis is to develop a two degree of freedom model and use parametric analysis to demonstrate an optimization technique by varying several geometric characteristics on a single-track vehicle. Furthermore, a dynamic vibration absorber will be added to the model to demonstrate its effect on the system. …

Closed Form Solutions To The Optimality Equation Of Minimal Norm Actuation, Jorge Antonio Guerra

LSU Master's Theses

This research focused on the problem of minimal norm actuation in the context of partial natural frequency or pole assignment applied to undamped vibrating systems by state feedback control. The result of the research was the closed form solutions for the minimal norm control input and gain vectors. These closed form solutions should took open loop eigenpairs and the desired frequencies of the controlled system and outputted the optimal controller parameters. This optimization technique ensures that the system’s dynamics will be effectively controlled while keeping the controller effort minimal. The controller must then be able to shift only the desired …

Effects Of Partial Confinement And Local Heating On Healing Efficiencies Of Self-Healing Particulate Composites, Jonah Champagne

LSU Master's Theses

Shape memory polymers are smart materials that can be trained to hold a temporary shape through programming and regain their original shape upon heating. Since there discovery in the 1960s, much research has been devoted to the study of these polymers. Of particular interest in recent years is the study of self-healing shape memory polymers. In a previous study, it has been shown that in order for efficient healing to take place in self-healing shape memory polymers, confinement during healing is essential. Moreover, a two-step close-then-heal (CTH) approach to healing was suggested. It was shown that use of this CTH …

Synthesis Of Poly(L-Lactic Acid) Scaffolds From Dioxane/Ethanol Using Control Rate Freezing And Study Of Its Microstructural Properties, George Idicula

LSU Master's Theses

Bio-degradable poly (l-lactic acid) (PLLA) scaffolds were prepared by using thermally induced phase separation (TIPS) method. A solution of PLLA-Dioxane was formed by dissolving PLLA in dehydrated 1,4-Dioxane at three wt/vol percentages, specifically 3, 7 and 10%. This PLLA-Dioxane solution was then frozen in borosilicate glass vials (5mL) at three cooling rates (1, 10 and 40 ˚C/min) in a commercially available controlled rate freezer (CRF). The frozen solution was freeze-dried to sublimate the Dioxane. The microstructural properties of the resulting PLLA scaffolds were determined utilizing Scanning Electron Microscopy (SEM) images and uni- axial compressive testing. The relationship between the wt/vol …

Mechanistic Analysis And Reduced Order Modeling Of Forced Film Cooling Flows, Guillaume Francois Bidan

LSU Doctoral Dissertations

Abstract Unforced and forced film cooling jets are investigated in view to develop a reduced order model of the velocity and temperature fields. First, a vertical jet in cross-flow, a configuration well documented at high blowing ratios, is investigated at low blowing ratios using experimental visualizations and large eddy simulations. The unforced study reveals that dominant structures at low blowing ratio can be significantly different from the ones formed at high blowing ratio and describes their evolution and transition as the blowing ratio is changed. The forced jet investigations extend the results of past numerical studies in terms of starting …

Micro & Nano Scale Mechanical Testing And Assembly With Applications To Metal Based Microsystems, Ke Chen

LSU Doctoral Dissertations

Metal-based high-aspect-ratio microscale structures (HARMS) are fundamental building blocks for functional metallic micro devices. This dissertation focuses on addressing several problems in fabrication and assembly of metal based microchannel devices. First, the materials’ responses to mechanical deformation at micro & nano scales, namely the mechanical “size effect”, have been explored by molding single crystal Al with long rectangular diamond punches and long wedge shaped indenters. It is noticed that the contact pressure of rectangular punches pressed into single crystal Al strongly depends on the punch width, while that of long wedge shaped indenters depends on the included wedge angle. We …

Topology And Shape Optimization Of Hydrodynamically–Lubricated Bearings For Enhanced Load-Carrying Capacity, Mohammad Fesanghary

LSU Doctoral Dissertations

Bearings are basic and essential components of nearly all machinery. They must be designed to work under different loads, speeds, and environments. Of all the performance parameters, load-carrying capacity (LCC) is often the most crucial design constraint. The objective of this research is to investigate different design methodologies that significantly improve the LCC of liquid-lubricated bearings. This goal can be achieved by either altering the surface texture or the bearing geometrical configuration. The methodology used here is based on mathematical topological/shape optimization algorithms. These methods can effectively improve the design performance while avoiding time-consuming trial-and-error design techniques. The first category …

Graph Rigidity-Based Formation Control Of Planar Multi-Agent Systems, Xiaoyu Cai

LSU Doctoral Dissertations

A multi-agent system is a network of interacting "agents" that collectively perform a complex task. This dissertation is concerned with the decentralized formation control of multi-agent systems moving in the plane. The formation problem is defined as designing control inputs for the agents so that they form and maintain a pre-defined, planar geometric shape. The focus is on three related problems with increasing level of complexity: formation acquisition, formation maneuvering, and target interception. Three different "dynamic" models, also with increasing level of complexity, are considered for the motion of the agents: the single-integrator model, the double-integrator model, and the full …

Modeling And Simulation Of Surface Profile Forming Process Of Microlenses And Their Application In Optical Interconnection Devices, Zhengyu Miao

LSU Doctoral Dissertations

Free space micro-optical systems require to integrate microlens array, micromirrors, optical waveguides, beam splitter, etc. on a single substrate. Out-of-plane microlens array fabricated by direct lithography provides pre-alignment during mask fabrication stage and has the advantage of mass manufacturing at low cost. However, this technology requires precise control of the surface profile of microlenses, which is a major technical challenge. The quality control of the surface profile of microlenses limits their applications. In this dissertation, the surface forming process of the out-of-plane microlenses in UV-lithography fabrication was modeled and simulated using a simplified cellular automata model. The microlens array was …

Multiscale Analysis Of Contact In Smooth And Rough Surfaces: Contact Characteristics And Tribo-Damage, Ali Beheshti

LSU Doctoral Dissertations

This dissertation is comprised of two major interrelated foci. The first focus is to investigate the effect of surface roughness on the behavior of dry contacting bodies through both deterministic and statistical approaches. In the current research, different statistical micro-contact models are employed together with the bulk deformation of the bounding solids to predict the characteristics of the dry rough line-contact and elliptical point-contact including the apparent pressure profile, contact dimensions and real area of contact. Further, based on the results of numerical simulations, useful relationships are provided for the contact characteristics. In addition, a robust approach for the deterministic …

Characterization And Verification Of A Closed Loop Wind Tunnel With A Linear Cascade And Upstream Wake Generator, Christopher Foreman

LSU Master's Theses

A closed loop wind tunnel designed to study film cooling was completed in May 2011 along with a removable wake generating device. The test section featured a three blade, four passage linear cascade utilizing the Air Force Office of Scientific Research L1A low pressure turbine blade. The wake generator is unique because its blades are flat plates with round leading and trailing edges instead of circular rods. In this report, the test section of the wind tunnel is characterized and validated through velocity and pressure measurements in the test section. Hot-wire surveys were used to characterize the velocity and turbulence …

Separation Control On High Lift Low-Pressure Turbine Airfoils Using Pulsed Vortex Generator Jets, Ralph J. Volino, Mounir B. Ibrahim

Mechanical Engineering Faculty Publications

Boundary layer separation control has been studied using vortex generator jets (VGJs) on a very high lift, low-pressure turbine airfoil. Experiments were done under low (0.6%) freestream turbulence conditions on a linear cascade in a low speed wind tunnel. Pressure surveys on the airfoil surface and downstream total pressure loss surveys were documented. Instantaneous velocity profile measurements were acquired in the suction surface boundary layer. Cases were considered at Reynolds numbers (based on the suction surface length and the nominal exit velocity from the cascade) of 25000 and 50000. Jet pulsing frequency and duty cycle were varied. In cases without …

A Study On Implementation Of Co2 Abatement Solutions For Existing Ships, Young C. Kwon

World Maritime University Dissertations

Recent high fuel prices and global economic recessions have driven shipowners to turn their attention to saving operational costs of their ships. For this reason, a variety of energy saving solutions has been developed and proposed in order to improve energy efficiency of ships. In addition, IMO have also proposed the best practices for energy saving solutions for existing ships through the SEEMP Guidelines. However, these proposed energy saving solutions (i.e. CO2 abatement solutions) do not give sufficient reliability due to the uncertainties of various parameters surrounding ships. These uncertainties may have a significant impact on effectiveness of individual energy …

Comparison Of 4d Phase-Contrast Mri Flow Measurements To Computational Fluid Dynamics Simulations Of Cerebrospinal Fluid Motion In The Cervical Spine, Theresia Yiallourou, Jan Robert Kroger, Nikolaos Stergiopulos, David Maintz, Bryn A. Martin, Alexander C. Bunck

Mechanical Engineering Faculty Research

Cerebrospinal fluid (CSF) dynamics in the cervical spinal subarachnoid space (SSS) have been thought to be important to help diagnose and assess craniospinal disorders such as Chiari I malformation (CM). In this study we obtained time-resolved three directional velocity encoded phase-contrast MRI (4D PC MRI) in three healthy volunteers and four CM patients and compared the 4D PC MRI measurements to subject-specific 3D computational fluid dynamics (CFD) simulations. The CFD simulations considered the geometry to be rigid-walled and did not include small anatomical structures such as nerve roots, denticulate ligaments and arachnoid trabeculae. Results were compared at nine axial planes …

Stress And Strain Adaptation In Load-Dependent Remodeling Of The Embryonic Left Ventricle, Christine Buffinton

Faculty Journal Articles

Altered pressure in the developing left ventricle (LV) results in altered morphology and tissue material properties. Mechanical stress and strain may play a role in the regulating process. This study showed that confocal microscopy, three-dimensional reconstruction, and finite element analysis can provide a detailed model of stress and strain in the trabeculated embryonic heart. The method was used to test the hypothesis that end-diastolic strains are normalized after altered loading of the LV during the stages of trabecular compaction and chamber formation. Stage-29 chick LVs subjected to pressure overload and underload at stage 21 were reconstructed with full trabecular morphology …

A Finite Difference Implementation Of Phase Field Theory, Nicholas W. Oren

Master's Theses

Computationally handling cracks generally results in numerically unstable results. Specifically handling the infinite stresses at the crack tip as well as the abrupt change from virgin material to failed material creates numerical instabilities. This project seeks to determine if phase field physics theory, particularly the physics based modification developed by B. N. Cassenti, can be appropriately applied to cracks. Phase field theory introduces an additional state variable, the phase of the material. The phase represents the level of failure (by cracking), and diffuses the failure along a crack by specified equations. The modification, based on a variational principle, was tested …

Production Of A Banjo: Development Of Manufacturing Processes For Banjo Resonators,Rims, And Necks., Kevin N. Zollinger

Undergraduate Honors Theses

This body of research focused on the development of prototype tooling and manufacturing processes to produce resonators, rims, and necks for building banjos. The resulting fixtures and manufacturing processes were designed for ease of use by a single employee in a small shop environment. This research required proficiency in interdisciplinary mediums (ie. 2D modeling, 3D modeling, centerline tool path program generation, 2D modeling, 3D modeling, rendering, design, and woodworking).

The resonator required development of a matching set of forming surfaces, a bending/gluing fixture, a work-holding fixture for utilizing a wood lathe, and a steam chamber required for bending strips of …

High Performance Low Temperature Solid Oxide Fuel Cells With Novel Electrode Architecture, Yu Chen, Qian Liu, Zhibin Yang, Fanglin Chen, Minfang Han

Faculty Publications

In this study, we have fabricated high performance low temperature solid oxide fuel cells (LT-SOFCs) with both acicular anodes and cathodes with thin Gd-doped ceria (GDC) electrolyte film. The acicular Ni-Gd_0.1Ce_0.9O_2−δ (Ni-GDC) anode was prepared using freeze drying tape casting, while the hierarchically porous cathode with nano-size Sm_0.5Sr_0.5CoO₃ (SSC) particles covering an acicular GDC skeleton was prepared by a combination of freeze drying tape casting and self-rising approaches. The acicular electrodes with 5–200 μm pores/channels enhance mass transport, while SSC particles of about 50 nm in the cathode promote …