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Wearable Devices For Single-Cell Sensing And Transfection, Lingqian Chang, Yu-Chieh Wang, Faheem Ershad, Ruiguo Yang, Cunjiang Yu, Yubo Fan 2019 Beihang University, Beijing

Wearable Devices For Single-Cell Sensing And Transfection, Lingqian Chang, Yu-Chieh Wang, Faheem Ershad, Ruiguo Yang, Cunjiang Yu, Yubo Fan

Department of Mechanical and Materials Engineering: Faculty Publications

Wearable healthcare devices are mainly used for biosensing and transdermal delivery. Recent advances in wearable biosensors allow for long-term and real-time monitoring of physiological conditions at a cellular resolution. Transdermal drug delivery systems have been further scaled down, enabling wide selections of cargo, from natural molecules (e.g., insulin and glucose) to bioengineered molecules (e.g., nanoparticles). Some emerging nanopatches show promise for precise single-cell gene transfection in vivo and have advantages over conventional tools in terms of delivery efficiency, safety, and controllability of delivered dose. In this review, we discuss recent technical advances in wearable micro/nano devices with unique capabilities or …


Framed Human Powered Vehicle Frame, Keyanna Brielle Henderson, Brendon Howard Morey, Kyra Noelle Schmidt, Austin Patrick Henry 2019 California Polytechnic State University, San Luis Obispo

Framed Human Powered Vehicle Frame, Keyanna Brielle Henderson, Brendon Howard Morey, Kyra Noelle Schmidt, Austin Patrick Henry

Mechanical Engineering

The following is the Final Design Review (FDR) Report for Framed, a team tasked with designing and fabricating the frame of the 2018-2019 Cal Poly Human Powered Vehicle (HPV) Club bike. The bike is to be raced at the 2019 World Human Powered Speed Challenge in Battle Mountain, Nevada with the goal of breaking the American collegiate speed record. The purpose of the FDR Report is to introduce the project’s background and objectives, discuss the final design, and present the results of manufacturing and testing. Prior to beginning work on the design of the frame, the group conducted extensive research …


Vaccine Cooler For The Global Poor, Benjamin J. Larson, Cooper E. Gibson, Eilbron Younan, Cody R. Volk 2019 California Polytechnic State University, San Luis Obispo

Vaccine Cooler For The Global Poor, Benjamin J. Larson, Cooper E. Gibson, Eilbron Younan, Cody R. Volk

Mechanical Engineering

Cal Poly physics professors Peter Schwartz and Nathan Heston approached the Solar Freeze team with the problem that remote communities in Africa have limited access to modern-day medicine or vaccines. They suggested that we try and design a cooling device that can keep vaccines cold for multiple days at a time while the medicine is transported to remote villages. Currently, there are vaccine cooler products on the market, but most of them are very expensive or lack portability. Peter and Nate have tasked the Solar Freeze team to come up with a less expensive solution that is also portable and …


Solar Tracking Using A Parallel Manipulator Mechanism To Achieve Two-Axis Position Tracking, Joseph Otto Hubach 2019 Rose-Hulman Institute of Technology

Solar Tracking Using A Parallel Manipulator Mechanism To Achieve Two-Axis Position Tracking, Joseph Otto Hubach

Graduate Theses - Mechanical Engineering

A novel solar tracker is presented that uses a parallel manipulator for the tracking mechanism instead of a traditional serial manipulator. The motivation is to create a solar tracker that displays the advantages of two-axis tracking systems (e.g., increased exposure to incident radiation, and enabling the use of efficient concentrating solar cells) while addressing some of the disadvantages of current two-axis tracking systems (e.g., the difficulties associated with having actuators mounted to moving elements within the mechanism). The mobility of the proposed parallel manipulator is examined using Grübler’s Criterion to establish that the manipulator displays the required two degrees of …


Danny’S Recumbent Bike Accessibility Device Final Design Report, Joseph J. Lee, Huy Nguyen, Jack McAtee, John Kulick 2019 California Polytechnic State University, San Luis Obispo

Danny’S Recumbent Bike Accessibility Device Final Design Report, Joseph J. Lee, Huy Nguyen, Jack Mcatee, John Kulick

Mechanical Engineering

The purpose of this document is to fully define our design solution and explain our manufacturing and testing results. Our project’s goal is to find a way to allow Danny Knutson, a retired Navy pilot and incomplete quadriplegic with limited use of his arms and an impaired sense of balance, to enter and exit his recumbent tricycle without any discomfort for him or his aide. We completed multiple interviews with Danny, patent research, existing product research, and other technical literature research in order to fully understand the problem. We synthesized this information to create a concrete list of customer wants …


Go With The Flow, Scott Weinhardt, Priscilla Ng, Ben Rydberg, Ritika Makhijani 2019 California Polytechnic State University, San Luis Obispo

Go With The Flow, Scott Weinhardt, Priscilla Ng, Ben Rydberg, Ritika Makhijani

Mechanical Engineering

This Final Design Review (FDR) report outlines the Fuel System Flow Analysis senior project completed by the presenters listed. Included is research about Solar Turbines’ needs, and objectives for our project, our design decision process and final design, manufacturing, design verification report, final results, and suggestions moving forward with this experiment. The goal of the project is to identify stable pressure fields throughout the Solar Turbines fuel delivery system. Specifically, the optimal placement for taking measurements downstream of the main and pilot fuel control valves. The data is used to validate the accuracy of computational fluid dynamic (CFD) models that …


Construction Of A Hyperspectral Camera Using Off-The-Shelf Parts And 3d-Printed Parts, Connor Heo 2019 University of Arkansas, Fayetteville

Construction Of A Hyperspectral Camera Using Off-The-Shelf Parts And 3d-Printed Parts, Connor Heo

Mechanical Engineering Undergraduate Honors Theses

The Arkansas Center for Space and Planetary Sciences (ACSPS) is working together with the Mechanical Engineering Department to build a modifiable camera with 3D-printed parts and off-the-shelf parts (sourced from Edmund Optics and Amazon). The design is to be readily changeable, primarily with the 3D printed parts, as to accommodate new ideas and functionalities in the future. Ultimately, the camera should be relatively cheap while maintaining functionality for proposed use cases. Earlier versions of the design will be tested extensively and rapidly updated in the ACSPS labs with benchtop testing. This will involve subjects with both visible and infrared emissions, …


Universal Bike Suspension Design, Ernesto Huerta, Gregory Ryan Ritter, Chris Michael Fedor, Michael Wu 2019 California Polytechnic State University, San Luis Obispo

Universal Bike Suspension Design, Ernesto Huerta, Gregory Ryan Ritter, Chris Michael Fedor, Michael Wu

Mechanical Engineering

Cal Poly Bike Builders (CPBB) is a student club at Cal Poly helping students design and fabricate their own bicycles. Currently, club members build rigid frames and mountain bikes with only front-suspension–commonly referred to as a “hardtail”. As more students join the club, interest grows in building full-suspension mountain bikes (FSMTB). Designing and manufacturing a mountain bike rear-suspension system requires a diverse skillset and a substantial time commitment. As a result, individual efforts building FSMTB have proven unsuccessful. The scope of this project is to develop a defined method and necessary tools such that all CPBB members can efficiently build …


Methods To Remotely Eliminate Biofilm From Medical Implants Using 2.4 Ghz Microwaves, Brett Glenn 2019 University of Arkansas, Fayetteville

Methods To Remotely Eliminate Biofilm From Medical Implants Using 2.4 Ghz Microwaves, Brett Glenn

Mechanical Engineering Undergraduate Honors Theses

Infections associated with biofilm growth are usually challenging to eradicate due to their high tolerance toward antibiotics [11, 12]. Biofilms often form on the inert surfaces of medically implanted devices [13]. No matter the sophistication, microbial infections can develop on all medical devices and tissue engineering constructs [12]. Related infections lead to 2 million cases annually in the U.S., costing the healthcare system over $5 billion in additional healthcare expenses [12].

Novel solutions to biofilm’s microbial colonization span the spectrum of engineering and science disciplines. Yet a practical solution still does not exist. The research presented here will explore a …


Thermal Management Design Tool System For Cubesat Applications, Siakrishna Reddy Kanumuru 2019 Morehead State University

Thermal Management Design Tool System For Cubesat Applications, Siakrishna Reddy Kanumuru

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Science at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science by Saikrishna Reddy Kanumuru on April 26, 2019.


Influence Of Metal Additives On Microstructure And Properties Of Amorphous Metal–Sioc Composites, Kaisheng Ming, Qing Su, Chao Gu, Dongyue Xie, Yongqiang Wang, Michael Nastasi, Jian Wang 2019 University of Nebraska-Lincoln

Influence Of Metal Additives On Microstructure And Properties Of Amorphous Metal–Sioc Composites, Kaisheng Ming, Qing Su, Chao Gu, Dongyue Xie, Yongqiang Wang, Michael Nastasi, Jian Wang

Department of Mechanical and Materials Engineering: Faculty Publications

Strong, ductile, and irradiation-tolerant structural materials are in urgent demand for improving the safety and efficiency of advanced nuclear reactors. Amorphous ceramics could be promising candidates for high irradiation tolerance due to thermal stability and lack of crystal defects. However, they are very brittle due to plastic flow instability. Here, we realized enhanced plasticity of amorphous ceramics through compositional and microstructural engineering. Two metal–amorphous ceramic composites, Fe-SiOC and Cu-SiOC, were fabricated by magnetron sputtering. Iron atoms are preferred to form uniformly distributed nano-sized Fe-rich amorphous clusters, while copper atoms grow non-uniformly distributed nano-crystalline Cu particles. The Fe-SiOC composite exhibits high …


Detection And Classification Of Vibrating Objects In Sar Images, Francisco German Perez Venegas 2019 University of New Mexico

Detection And Classification Of Vibrating Objects In Sar Images, Francisco German Perez Venegas

Electrical and Computer Engineering ETDs

The vibratory response of buildings and machines contains key information that can be exploited to infer their operating conditions and to diagnose failures. Furthermore, since vibration signatures observed from the exterior surfaces of structures are intrinsically linked to the type of machinery operating inside of them, the ability to monitor vibrations remotely can enable the detection and identification of the machinery.

This dissertation focuses on developing novel techniques for the detection and M-ary classification of vibrating objects in SAR images. The work performed in this dissertation is conducted around three central claims. First, the non-linear transformation that the micro-Doppler return …


Restore-L Satellite Servicing Internship Final Report, Giovanni Campos 2019 CUNY New York City College of Technology

Restore-L Satellite Servicing Internship Final Report, Giovanni Campos

Publications and Research

This paper reviews the Restore-L mission purpose and the necessary research and simulations to meet mission specification for the Propellant Transfer Subsystem (PTS). It is essential the PTS undergoes functionality testing, environmental testing, and calculations to understand the capabilities of the system. For the testing of components from PTS, a proper test setup is required. It is vital for test hardware, such as hoses and valves, to stay in place while the test is being performed. For the test hardware to operate correctly, positioning, orientation, and alignment are critical as well. In addition to the testing, calculations for pressure drop …


Biomechanical Foot Guidance Linkage, Carl Nelson, Cale J. Stolle, Judith M. Burnfield 2019 Lincoln, NE

Biomechanical Foot Guidance Linkage, Carl Nelson, Cale J. Stolle, Judith M. Burnfield

Department of Mechanical and Materials Engineering: Faculty Publications

A gait replication apparatus can include a scalable mechanical mechanism configured to replicate different gaits . The scalable mechanical mechanism can include , for example , a four - bar linkage , a pantograph , a cam / Scotch - yoke mechanism , and so forth . In some embodiments , the mechanical mechanism includes a beam rotating about an axis passing proximate to its center , with a foot pedal slidably coupled with the beam , and a timing chain / belt or cable pulley - pair coupled with the foot pedal and looped about the beam . A …


Impact Of Pulse Length On The Accuracy Of Defect Depth Measurements In Pulse Thermography, James Pierce, Nathan B. Crane 2019 University of South Florida, Tampa

Impact Of Pulse Length On The Accuracy Of Defect Depth Measurements In Pulse Thermography, James Pierce, Nathan B. Crane

Faculty Publications

Pulse thermography is a nondestructive testing method in which an energy pulse is applied to a surface while the surface temperature evolution is measured to detect sub surface defects and estimate their depth. This nondestructive test method was developed on the assumption of instantaneous surface heating, but recent work has shown that relatively long pulses can be used to accurately determine defect depth in polymers. This paper examines the impact of varying input pulse length on the accuracy of defect depth quantification as a function of the material properties. Simulations using both thermoplastics and metals show that measurement error is …


Effect Of Low Temperature Heat Treatments On The Resulting Void Analysis Of Blown Power Deposition Inconel 625 Specimens, Noah Naden, An Nguyen 2019 University of Alabama in Huntsville

Effect Of Low Temperature Heat Treatments On The Resulting Void Analysis Of Blown Power Deposition Inconel 625 Specimens, Noah Naden, An Nguyen

Research Horizons Day Posters

No abstract provided.


Soft , Multilayered Electronics For Wearable Devices And Methods To Produce The Same, Carmel Majidi, Michael D. Bartlett, Eric J. Markvicka 2019 University of Nebraska - Lincoln

Soft , Multilayered Electronics For Wearable Devices And Methods To Produce The Same, Carmel Majidi, Michael D. Bartlett, Eric J. Markvicka

Department of Mechanical and Materials Engineering: Faculty Publications

Disclosed herein is an efficient fabrication approach to create highly customizable wearable electronics through rapid laser machining and adhesion - controlled soft materials assembly . Well - aligned , multi - layered materials can be created from 2D and 3D elements that stretch and bend while seamlessly integrating with rigid components such as micro chip integrated circuits ( IC ) , discrete electrical components , and interconnects . These techniques are applied using commercially available materials . These materials and methods enable custom wearable electronics while offering versatility in design and functionality for a variety of bio - monitor ing …


Microwave Self-Healing Technology As Airfield Porous Asphalt Friction Course Repair And Maintenance System, Amir Tabakovic, Declan O'Prey, Drew McKenna, David Woodward 2019 Technological University Dublin

Microwave Self-Healing Technology As Airfield Porous Asphalt Friction Course Repair And Maintenance System, Amir Tabakovic, Declan O'Prey, Drew Mckenna, David Woodward

Research and Innovation - Articles

A problem increasingly faced by airport authorities is the maintenance of runways. Due to their large aircraft loadings associated with take-off and landing operations, runways experience surface deterioration. Poor quality runway surfaces cannot be tolerated in such an environment. Maintenance issues must be carried out to maximise safety and minimise the risk of aircraft damage. A recent development has been the introduction of self-healing technologies such as rejuvenator encapsulation, induction and microwave heating to address these issues. This paper summarises a laboratory investigation to determine the effectiveness of microwave self-healing for crack repair of Porous Friction Course (PFC) used for …


Gastrointestinal Sensor Implantation System, Benjamin Terry, Weston Lewis, Wanchuan Xie, Pengbo Li, Alfred Tsubaki 2019 Lincoln , NE

Gastrointestinal Sensor Implantation System, Benjamin Terry, Weston Lewis, Wanchuan Xie, Pengbo Li, Alfred Tsubaki

Department of Mechanical and Materials Engineering: Faculty Publications

A gastrointestinal ( GI ) sensor deployment device is dis closed . In implementations , the sensor deployment device includes an orally - administrable capsule with a tissue cap ture device removably coupled to the orally - administrable capsule . The tissue capture device includes a plurality of fasteners for connecting the tissue capture device to GI tissue within a body . A biometric sensor is coupled to the tissue capture device for continuous or periodic monitoring of the GI tract of the body at the GI tissue attachment location . A chamber within the orally - administrable capsule is …


Advanced Technology Lift Assist Systems - Atlas, Sebastian L. Gnagy, Ismael A. Rangel, Giovani Rodriguez, Tyler J. Hooks 2019 California Polytechnic State University, San Luis Obispo

Advanced Technology Lift Assist Systems - Atlas, Sebastian L. Gnagy, Ismael A. Rangel, Giovani Rodriguez, Tyler J. Hooks

Mechanical Engineering

EMS personal work hard every day to save lives. A big part of the job is helping to lift people who are notinjured but have fallen and can’t get up by themselves. There are currently no procedures or tools that areconsistently used by EMS in this specific situation. This leads to the response often being ad hoc costing more time, resources, and manpower that can be vital if multiple emergencies happen at the same time. Along with this the job of lifting an individual that is overweight is no easy feat and is one of the primary factors that leads …


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