Yap Mechanotransduction Under
Cyclic Mechanical Stretch Loading
For Mesenchymal Stem Cell
Osteogenesis Is Regulated
By Rock,
2024
University of Nebraska-Lincoln
Yap Mechanotransduction Under Cyclic Mechanical Stretch Loading For Mesenchymal Stem Cell Osteogenesis Is Regulated By Rock, Eunju Kim, Brandon D. Riehl, Tasneem Bouzid, Ruiguo Yang, Bin Duan, Henry J. Donahue, Jung Yul Lim
Department of Mechanical and Materials Engineering: Faculty Publications
While yes-associated protein (YAP) is now recognized as a potent mechanosensitive transcriptional regulator to affect cell growth and differentiation including the osteogenic transcription of mesenchymal stem cells (MSCs), most studies have reported the YAP mechanosensing of static mechanophysical cues such as substrate stiffness. We tested MSC response to dynamic loading, i.e., cyclic mechanical stretching, and assessed YAP mechanosensing and resultant MSC osteogenesis. We showed that cyclic stretching at 10% strain and 1 Hz frequency triggered YAP nuclear import in MSCs. YAP phosphorylation at S127 and S397, which is required for YAP cytoplasmic retention, was suppressed by cyclic stretch. We also …
Two-Phase Flow Simulations With Plic-Vof Method And Dynamic Mesh Refinement,
2024
University of Texas at Arlington
Two-Phase Flow Simulations With Plic-Vof Method And Dynamic Mesh Refinement, Vimalan Adaikalanathan
Mechanical and Aerospace Engineering Dissertations - Archive
Two-phase flows are critical in a variety of engineering applications that span multiple length scales. These applications encompass macroscopic phenomena, such as dam breakage and wave-structure interactions, as well as microscopic events, including droplet impacts and boiling, and mixed-scale issues like spray dynamics. Accurate representation of evolving interfaces is essential for numerical simulations of these problems, and the Volume of Fluid (VOF) method combined with the Piecewise Linear Interface Calculation (PLIC) approach is employed to fulfill this requirement. To tackle the computational challenges associated with high-resolution meshes in deforming two-phase flows, Adaptive Mesh Refinement (AMR) is utilized to enhance mesh …
Introduce Ultrasound Fabry-Pérot Resonator For Attenuation Characterization And Sensitization Detection Of Aluminum-Magnesium Alloys,
2024
University of Texas at Arlington
Introduce Ultrasound Fabry-Pérot Resonator For Attenuation Characterization And Sensitization Detection Of Aluminum-Magnesium Alloys, Songwei Wang
Mechanical and Aerospace Engineering Dissertations - Archive
The Ultrasound Fabry-Pérot Resonator (UFPR) is introduced as a novel technique for non-destructive evaluation and material characterization. By adapting optical Fabry-Pérot Resonator principles to ultrasonic systems, UFPR inherits advantages such as enhanced sensitivity, reduced uncertainty, and the capabilities of frequency-dependent analysis and fringe spectral analysis. This study focuses on UFPR’s application to ultrasonic attenuation characterization and sensitization detection in aluminum-magnesium alloys, which are critical for understanding microstructural changes and improving material performance.
The research was conducted in three systematic steps. First, time-frequency analysis was utilized to examine frequency-dependent attenuation behavior, establishing a foundation for ultrasonic attenuation characterization. Second, longitudinal UFPR …
Articulating Balsa Wood Bridge,
2024
Central Washington University
Articulating Balsa Wood Bridge, Nate Harris
All Undergraduate Projects
This report describes the design, construction, and testing of a small-scale articulating balsa wood bridge that allowed passage over normally impassable terrain. The bridge was required to span a 400mm gap, while also articulating the midpoint of the bridge 140mm above its resting position. The bridge also needed to support a 20kg (44 lbs.) point load in the center of the bridge, and the bridge and articulation tower together needed to weigh less than 85 (0.19 lbs.) grams.
To construct the bridge, statics and mechanics of materials was used to design a truss that was calculated to support the load …
Tractor Test 2280: John Deere 9rt 490 Diesel,
2024
University of Nebraska-Lincoln
Tractor Test 2280: John Deere 9rt 490 Diesel, Nebraska Tractor Test Lab
Nebraska Tractor Tests
ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …
Tractor Test #2295: Kubota M7-174,
2024
University of Nebraska-Lincoln
Tractor Test #2295: Kubota M7-174, Nebraska Tractor Test Lab
Nebraska Tractor Tests
ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …
Tractor Test # 2285: Claas Axion 940,
2024
University of Nebraska-Lincoln
Tractor Test # 2285: Claas Axion 940, Nebraska Tractor Test Lab
Nebraska Tractor Tests
ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …
Reflections Of Undergraduate Engineering Students Completing A Cross Disciplinary Robotics Project With Pre-Service Teachers And Fifth Graders In An Electromechanical Systems Course,
2024
Old Dominion University
Reflections Of Undergraduate Engineering Students Completing A Cross Disciplinary Robotics Project With Pre-Service Teachers And Fifth Graders In An Electromechanical Systems Course, Krishnanand Kaipa, Jennifer Kidd, Isaac Koduah Kumi, Stacie I. Ringleb, Orlando M. Ayala, Kristie Gutierrez, Francisco Cima, Danielle Marie Rhemer
Mechanical & Aerospace Engineering Faculty Publications
Engineering is becoming increasingly cross-disciplinary, requiring students to develop skills in multiple engineering disciplines (e.g., mechanical engineering students having to learn the basics of electronics, instrumentation, and coding) and interprofessional skills to integrate perspectives from people outside their field. In the workplace, engineering teams are frequently multidisciplinary, and often, people from outside of engineering are part of the team that brings a product to market. Additionally, teams are often diverse in age, race, gender, and in other areas. Teams that creatively utilize the contrasting perspectives and ideas arising from these differences can positively affect team performance and generate solutions effective …
Tractor Test 2281: John Deere 9rt 540 Diesel,
2024
University of Nebraska-Lincoln
Tractor Test 2281: John Deere 9rt 540 Diesel, Nebraska Tractor Test Lab
Nebraska Tractor Tests
ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …
Tractor Test # 2283: Claas Axion 920,
2024
University of Nebraska-Lincoln
Tractor Test # 2283: Claas Axion 920, Nebraska Tractor Test Lab
Nebraska Tractor Tests
ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …
Nebraska Summary #1290: Massey Ferguson 8s 305,
2024
University of Nebraska-Lincoln
Nebraska Summary #1290: Massey Ferguson 8s 305, Nebraska Tractor Test Lab
Nebraska Tractor Tests
ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …
Nebraska Summary #1289: Massey Ferguson 8s 285,
2024
University of Nebraska-Lincoln
Nebraska Summary #1289: Massey Ferguson 8s 285, Nebraska Tractor Test Lab
Nebraska Tractor Tests
ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …
Nebraska Summary #1287: Massey Ferguson 8s 245,
2024
University of Nebraska-Lincoln
Nebraska Summary #1287: Massey Ferguson 8s 245, Nebraska Tractor Test Lab
Nebraska Tractor Tests
ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …
Nebraska Test #2288: Case Ih Steiger 475 Rowtrac,
2024
University of Nebraska-Lincoln
Nebraska Test #2288: Case Ih Steiger 475 Rowtrac, Nebraska Tractor Test Lab
Nebraska Tractor Tests
ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …
Nebraska Test #2287: Case Ih Steiger 425 Rowtrac,
2024
University of Nebraska-Lincoln
Nebraska Test #2287: Case Ih Steiger 425 Rowtrac, Nebraska Tractor Test Lab
Nebraska Tractor Tests
ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …
Nebraska Test #2292: Case Ih Steiger 645 Quadtrac,
2024
University of Nebraska-Lincoln
Nebraska Test #2292: Case Ih Steiger 645 Quadtrac, Nebraska Tractor Test Lab
Nebraska Tractor Tests
ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …
Nebraska Test #2291: Case Ih Steiger 595 Quadtrac,
2024
University of Nebraska-Lincoln
Nebraska Test #2291: Case Ih Steiger 595 Quadtrac, Nebraska Tractor Test Lab
Nebraska Tractor Tests
ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …
Nebraska Test #2279: Case Ih Steiger 525,
2024
University of Nebraska-Lincoln
Nebraska Test #2279: Case Ih Steiger 525, Nebraska Tractor Test Lab
Nebraska Tractor Tests
ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …
Numerical Simulation And Optimization Of Fin Configurations For Enhanced Heat Sink Performance In Aluminum And Copper Materials,
2024
University of Texas at Arlington
Numerical Simulation And Optimization Of Fin Configurations For Enhanced Heat Sink Performance In Aluminum And Copper Materials, Rimpy Singh
Mechanical and Aerospace Engineering Theses - Archive
The constant evolution of data centers and high-power electronic systems has raised critical challenges in heat dissipation and thermal management. Single-phase immersion cooling, where electronic components are submerged in a thermally conductive but non-electrically conductive liquid (dielectric liquid), offers improved heat dissipation capabilities and emerges as a promising alternative to traditional air-cooling methods, which often fail to meet the thermal demands of densely packed, high-power systems. This study investigates and compares the thermal performance of aluminum and copper heat sinks with fin thicknesses of 0.33 mm and 0.54 mm, respectively, using finite element analysis based on computational fluid dynamics (CFD) …
Droplet Analysis Of Spray Inside A Compact Column Gas Scrubber Through Shadowgraphy,
2024
University of Kentucky
Droplet Analysis Of Spray Inside A Compact Column Gas Scrubber Through Shadowgraphy, Brandon Heller
Theses and Dissertations--Mechanical and Aerospace Engineering
The shadowgraphy imaging technique was adapted to analyze the droplet field from a spray nozzle inside the gas absorption section of a compact column gas scrubber. This technique in conjunction with a developed image processing technique was able to gain statistical size information at different distances from two types of spray nozzles. The gas scrubber then ran a parametric campaign of eight operating conditions and statistical size information was captured for each case with the goal of understanding how operating conditions affect the droplet field properties. Lastly, several simulations were completed to understand how the addition of recirculation zones would …
