Modulating Notochordal Differentiation Of Human Induced Pluripotent Stem Cells Using Natural Nucleus Pulposus Tissue Matrix,
2014
Missouri University of Science and Technology
Modulating Notochordal Differentiation Of Human Induced Pluripotent Stem Cells Using Natural Nucleus Pulposus Tissue Matrix, Yongxing Liu, M. N. Rahaman, B. Sonny Bal
Materials Science and Engineering Faculty Research & Creative Works
Human induced pluripotent stem cells (hiPSCs) can differentiate into notochordal cell (NC)-like cells when cultured in the presence of natural porcine nucleus pulposus (NP) tissue matrix. The method promises massive production of high-quality, functional cells to treat degenerative intervertebral discs (IVDs). Based on our previous work, we further examined the effect of cell-NP matrix contact and culture medium on the differentiation, and further assessed the functional differentiation ability of the generated NC-like. The study showed that direct contact between hiPSCs and NP matrix can promote the differentiation yield, whilst both the contact and non-contact cultures can generate functional NC-like cells. …
Characterizing The Pore Structure Of Carbonated Natural Wollastonite,
2014
Purdue University
Characterizing The Pore Structure Of Carbonated Natural Wollastonite, Chiara Villani, Robert Spragg, Raikhan Tokpatayeva, Jan Olek, W. Jason Weiss
International Conference on Durability of Concrete Structures
This paper focuses on examining the pore structure of a cementitious paste made with a calcium silicate (wollastonite) that reacts with carbon dioxide and water to form a hardened solid. The pore structure of the hardened solid has been characterized using vapor sorption and desorption, low-temperature differential scanning calorimetry (LT-DSC), and scanning electron microscopy (SEM). The total porosity was also measured using mass measurement in oven-dry and vacuum-saturated conditions. Evidence exists that support the hypothesis that the solid has two main pore sizes: large macropores (>10 nm) appear to form between the initial calcium silicate particles and small micropores …
Developent Of A Phospholipid Encapsulation Process For Quantum Dots To Be Used In Biologic Applications,
2014
California Polytechnic State University, San Luis Obispo
Developent Of A Phospholipid Encapsulation Process For Quantum Dots To Be Used In Biologic Applications, Logan Grimes
Master's Theses
The American Cancer Society predicts that 1,665,540 people will be diagnosed with cancer, and 585,720 people will die from cancer in 2014. One of the most common types of cancer in the United States is skin cancer. Melanoma alone is predicted to account for 10,000 of the cancer related deaths in 2014. As a highly mobile and aggressive form of cancer, melanoma is difficult to fight once it has metastasized through the body. Early detection in such varieties of cancer is critical in improving survival rates in afflicted patients. Present methods of detection rely on visual examination of suspicious regions …
Material Composition And Toxicology Of Cosmetic Products,
2014
California Polytechnic State University - San Luis Obispo
Material Composition And Toxicology Of Cosmetic Products, Hilda Gonzalez
Materials Engineering
In today’s modern society, the U.S. Food and Drug Administration regulates many industries to protect consumers’ health; the cosmetics industry is not one of them. Through self-regulation, companies continue to sell products for topical use on the body that have been known to contain toxic chemicals with little to no testing on the effects they have on the human body. The purpose of this project was to determine the content of such known toxins in five different brands of face powders. X-Ray Diffraction (XRD) was used to verify the primary component and Inductively Coupled Plasma-Optical Emissions Spectroscopy (ICP-OES) was used …
Characterization Of 3d Interconnected Microstructural Network In Mixed Ionic And Electronic Conducting Ceramic Composites,
2014
University of South Carolina - Columbia
Characterization Of 3d Interconnected Microstructural Network In Mixed Ionic And Electronic Conducting Ceramic Composites, William M. Harris, Kyle S. Brinkman, Ye Lin, Dong Su, Alex P. Cocco, Arata Nakajo, Matthew B. Degostin, Yu-Chen Karen Chen-Wiegart, Jun Wang, Fanglin Chen, Yong S. Chu, Wilson K. S. Chiu
Faculty Publications
The microstructure and connectivity of the ionic and electronic conductive phases in composite ceramic membranes are directly related to device performance. Transmission electron microscopy (TEM) including chemical mapping combined with X-ray nanotomography (XNT) have been used to characterize the composition and 3-D microstructure of a MIEC composite model system consisting of a Ce0.8Gd0.2O2 (GDC) oxygen ion conductive phase and a CoFe2O4 (CFO) electronic conductive phase. The microstructural data is discussed, including the composition and distribution of an emergent phase which takes the form of isolated and distinct regions. Performance implications are considered …
Ceramic Welds, And A Method For Producing The Same,
2014
Missouri University of Science and Technology
Ceramic Welds, And A Method For Producing The Same, Greg Hilmas, William Fahrenholtz, Jeremy Lee Watts, Harlan James Brown-Shaklee
Materials Science and Engineering Faculty Research & Creative Works
A method of producing a ceramic weld, including identifying a ceramic first surface and a ceramic second surface to be bonded together, maintaining a non-oxidizing atmosphere over the first and second surfaces, and engaging the first and second surfaces to define a joint. An arc is generated between an electrode and the joint to create a liquid phase, and the liquid phase is cooled to yield a solid fusion layer, wherein the first and second surfaces are joined in the fusion layer.
Selection Of The Process Parameters For The Mass Plating Of Discrete Electronic Components,
2014
Technological University Dublin
Selection Of The Process Parameters For The Mass Plating Of Discrete Electronic Components, Ann Hopper
Articles
The miniaturisation of electronic components coupled with requirements for high temperature lead free soldering has forced the improvement of the termination finish of surface mount components to meet the critical demands of the electronic industry. In the present work the processing parameters necessary to plate miniature multilayer varistors (MLV’s) have been explored. The tooling selected was a “Rotary flow-thru’ plater” which achieved high volume plating with
Thermodynamics And Reaction Kinetics During Mechanochemical Synthesis And Environmental Testing Of Lanthanide And Actinide Refractory Materials,
2014
Boise State University
Thermodynamics And Reaction Kinetics During Mechanochemical Synthesis And Environmental Testing Of Lanthanide And Actinide Refractory Materials, Gordon Andrew Alanko
Boise State University Theses and Dissertations
High energy ball milling is a broad family of well-known techniques for materials processing that includes mechanochemical synthesis, in which the milled materials react during milling. The latter may involve components reacting in the solid, liquid, or gas phases, and the operative kinetics have hardly been studied. Several manufacturers of high energy ball mills have recently made available instrumented milling vessel lids. These lids are able to monitor the temperature of the lid and the gas pressure within the vessel in situ during milling experiments. This ability is a significant improvement over the ad hoc instrumentation setups sometimes discussed in …
Phase Transformations In Calcium Substituted Lanthanum Ferrite,
2014
Boise State University
Phase Transformations In Calcium Substituted Lanthanum Ferrite, Patrick M. Price
Boise State University Theses and Dissertations
Increasing world energy demands are still heavily dependent on fossil fuels. To meet these demands, crude oil is increasingly being extracted from remote locations where natural gas pipelines do not exist. It is not profitable for oil and gas companies to transport natural gas by ship or truck from these remote locations so it is combusted on site in the form of gas flares. Critics oppose this practice due to the environmental impact from pollution and carbon emissions created during the flaring process. Oil and gas companies are eager to find profitable ways to eliminate natural gas lines in order …
Experimental Investigation Of Mechanical Behavior Of An Oxide/Oxide Ceramic Composite In Interlaminar Shear And Under Combined Tension-Torsion Loading,
2014
Air Force Institute of Technology
Experimental Investigation Of Mechanical Behavior Of An Oxide/Oxide Ceramic Composite In Interlaminar Shear And Under Combined Tension-Torsion Loading, Skyler R. Hilburn
Theses and Dissertations
Creep behavior in interlaminar shear of an oxide-oxide ceramic composite, Nextel 720™/aluminosilicate (N720/AS), was investigated at 1100°C in laboratory air and in steam. The interlaminar shear strength (ILSS) was determined as 7.65 MPa. The creep behavior was examined for interlaminar shear stresses in the 2-6 MPa range. Primary and secondary creep regimes were observed in all tests conducted in air and in steam. Tertiary creep was noted in the tests performed at 6 MPa. Larger creep strains and higher creep strain rates were produced in steam. Surprisingly, the presence of steam had a beneficial effect on creep lifetimes. It appears …
Nanostructured Dielectric Materials For High Energy Density Multilayer Ceramic Capacitors,
2014
Missouri University of Science and Technology
Nanostructured Dielectric Materials For High Energy Density Multilayer Ceramic Capacitors, Fatih Dogan, Alan Devoe, Ian Burns
Materials Science and Engineering Faculty Research & Creative Works
A multilayer ceramic capacitor, having a plurality of electrode layers and a plurality of substantially titanium dioxide dielectric layers, wherein each respective titanium dioxide dielectric layer is substantially free of porosity, wherein each respective substantially titanium dioxide dielectric layer is positioned between two respective electrode layers, wherein each respective substantially titanium dioxide dielectric layer has an average grain size of between about 200 and about 400 nanometers, wherein each respective substantially titanium dioxide dielectric layer has maximum particle size of less than about 500 nanometers. Typically, each respective substantially titanium dioxide dielectric layer further includes at least one dopant selected …
Nanostructured Dielectric Materials For High Energy Density Multilayer Ceramic Capacitors,
2014
Missouri University of Science and Technology
Nanostructured Dielectric Materials For High Energy Density Multilayer Ceramic Capacitors, Fatih Dogan, Alan Devoe, Ian Burn
Materials Science and Engineering Faculty Research & Creative Works
A multilayer ceramic capacitor, having a plurality of electrode layers and a plurality of substantially titanium dioxide dielectric layers, wherein each respective titanium dioxide dielectric layer is substantially free of porosity, wherein each respective substantially titanium dioxide dielectric layer is positioned between two respective electrode layers, wherein each respective substantially titanium dioxide dielectric layer has an average grain size of between about 200 and about 400 nanometers, wherein each respective substantially titanium dioxide dielectric layer has maximum particle size of less than about 500 nanometers. Typically, each respective substantially titanium dioxide dielectric layer further includes at least one dopant selected …
A Novel Injectable Borate Bioactive Glass Cement As An Antibiotic Delivery Vehicle For Treating Osteomyelitis,
2014
Missouri University of Science and Technology
A Novel Injectable Borate Bioactive Glass Cement As An Antibiotic Delivery Vehicle For Treating Osteomyelitis, Hao Ding, Cunju Zhao, Xu Cui, Yifei Gu, Weitao Jia, M. N. Rahaman, Yang Wang, Wenhai Huang, Changqing Zhang
Materials Science and Engineering Faculty Research & Creative Works
Background: A novel injectable cement composed of chitosan-bonded borate bioactive glass (BG) particles was evaluated as a carrier for local delivery of vancomycin in the treatment of osteomyelitis in a rabbit tibial model. Materials and Methods: The setting time, injectability, and compressive strength of the borate BG cement, and the release profile of vancomycin from the cement were measured in vitro. The capacity of the vancomycin-loaded BG cement to eradicate methicillin-resistant Staphylococcus aureus (MRSA)-induced osteomyelitis in rabbit tibiae in vivo was evaluated and compared with that for a vancomycin-loaded calcium sulfate (CS) cement and for intravenous injection of vancomycin. Results: …
Development And Application Of Improved Shotctrete Refractory For Aluminum Rotary Furnace Applications,
2014
Missouri University of Science and Technology
Development And Application Of Improved Shotctrete Refractory For Aluminum Rotary Furnace Applications, James G. Hemrick, Angela Rodrigues-Schroer, Dominick Colavito, Jeffrey D. Smith, Kelley O'Hara
Materials Science and Engineering Faculty Research & Creative Works
Oak Ridge National Laboratory, in collaboration with refractory manufacturer Minteq International, Inc., academic partner Missouri University of Science and Technology and refractory end users have developed novel refractory systems and techniques to reduce energy consumption of refractory lined vessels. The objective of this U.S. DOE funded project was to address the need for innovative refractory compositions by developing novel gunnable refractory compositions for use in high temperature and high alkali environments. Developed materials utilized new aggregate materials, bond systems, protective coatings, and phase formation techniques. Under this project, materials were developed specifically for aluminum rotary dross furnace applications and a …
Spinel-Based Refractories For Improved Performance In Coal Gasification Environments,
2014
Missouri University of Science and Technology
Spinel-Based Refractories For Improved Performance In Coal Gasification Environments, James G. Hemrick, Beth Armstrong, Angela Rodrigues-Schroer, Dominick Colavito, Jeffrey D. Smith
Materials Science and Engineering Faculty Research & Creative Works
Oak Ridge National Laboratory, in collaboration with Minteq International, Inc., Missouri University of Science and Technology and refractory end users, has developed novel refractory systems and techniques to reduce energy consumption of refractory lined vessels. The objective of this U.S. DOE funded project was to address the need for innovative refractory compositions by developing MgO-Al2O3 spinel gunnable refractory compositions utilizing new aggregate materials, bond systems, protective coatings, and phase formation techniques. Materials have been developed specifically for coal gasification environments and work has been performed to develop and apply low cost coatings using a colloidal approach for …
Elevated Temperature Mechanical Properties Of Zirconium Diboride Based Ceramics,
2014
Missouri University of Science and Technology
Elevated Temperature Mechanical Properties Of Zirconium Diboride Based Ceramics, Eric W. Neuman
Doctoral Dissertations
"Research presented in this dissertation focused on the mechanical behavior of ZrB₂ based ceramic at elevated temperatures. Flexure strength, fracture toughness, and elastic modulus were measured at temperatures up to 2300ºC for three compositions: monolithic ZrB₂ (Z); ZrB₂ - 30 vol% SiC - 2 vol% B₄ C (ZS); and ZrB₂ - 10 vol% ZrC (ZC). In argon, Z, ZS, and ZC had strengths of 210 (at 2300ºC), 260 (at 2200ºC), and 295 MPa (at 2300ºC), the highest temperatures tested for each composition. Fractography was used extensively to characterize the strength limiting flaws as a function of temperature. Strength of ZS …
Effect Of Solid Solutions And Second Phases On The Thermal Conductivity Of Zirconium Diboride Ceramics,
2014
Missouri University of Science and Technology
Effect Of Solid Solutions And Second Phases On The Thermal Conductivity Of Zirconium Diboride Ceramics, Gregory John Kenneth Harrington
Doctoral Dissertations
"The research presented in this dissertation is focused on the thermal conductivity (k) of ZrB2 ceramics. The goal was to develop a better understanding of how various solid solutions and second phases affect the thermal and electrical transport in ZrB2, with a focus on the effect of C, W, and ZrC. The first study showed C additions improved densification and it was proposed that the reduction of boria was the impetus for this result. Boron carbide was formed by the reaction of excess C with reduced B and its formation was mitigated by the addition of ZrH …
Design, Fabrication, And Properties Of 2-2 Connectivity Cement/Polymer Based Piezoelectric Composites With Varied Piezoelectric Phase Distribution,
2014
University of South Carolina, United States
Design, Fabrication, And Properties Of 2-2 Connectivity Cement/Polymer Based Piezoelectric Composites With Varied Piezoelectric Phase Distribution, Xu Dongyu, Cheng Xin, Sourav Banerjee, Huang Shifeng
Faculty Publications
The laminated 2-2 connectivity cement/polymer based piezoelectric composites with variedpiezoelectric phase distribution were fabricated by employing Lead Zirconium Titanate ceramicas active phase, and mixture of cement powder, epoxy resin, and hardener as matrix phase with a mass proportion of 4:4:1. The dielectric, piezoelectric, and electromechanical coupling properties of the composites were studied. The composites with large total volume fraction ofpiezoelectric phase have large piezoelectric strain constant and relative permittivity, and thepiezoelectric and dielectric properties of the composites are independent of the dimensional variations of the piezoelectric ceramic layer. The composites with small total volume fraction of piezoelectric phase have large …
Freeze Thaw Durability Of Internally Cured Concrete Made Using Superabsorbent Polymers,
2014
Purdue University
Freeze Thaw Durability Of Internally Cured Concrete Made Using Superabsorbent Polymers, Wesley A. Jones, W. Jason Weiss
International Conference on Durability of Concrete Structures
The use of superabsorbent polymers (SAPs) to produce internally cured concrete has been shown to be effective in reducing the potential for restrained shrinkage cracking of high performance concrete mixtures. However, not much is known regarding the freeze–thaw durability of concrete mixtures that incorporate SAPs for internal curing (IC). When SAP particles desorb (or partially desorb) the “water” (pore fluid) they contain for the purposes of IC, some believe that the void space created by these particles can provide enough empty voids to accommodate the additional volume caused by water expansion upon freezing. This paper investigates the freeze–thaw durability of …
Influence Of Ferrite Phase In Alite-Calcium Sulfoaluminate Cements,
2014
University of Kentucky
Influence Of Ferrite Phase In Alite-Calcium Sulfoaluminate Cements, Tristana Y. Duvallet
Theses and Dissertations--Chemical and Materials Engineering
Since the energy crisis in 1970’s, research on low energy cements with low CO2-emissions has been increasing. Numerous solutions have been investigated, and the goal of this original research is to create a viable hybrid cement with the components of both Ordinary Portland cement (OPC) and calcium sulfoaluminate cement (CSAC), by forming a material that contains both alite and calcium sulfoaluminate clinker phases. Furthermore, this research focuses on keeping the cost of this material reasonable by reducing aluminum requirements through its substitution with iron. The aim of this work would produce a cement that can use large amounts …
