Engineering Science and Materials Commons^™

Systems Biology Of The Functional And Dysfunctional Endothelium, Jennifer Frueh, Nataly Maimari, Takayuki Homma, Sandra M. Bovens, Ryan M. Pedrigi, Leila Towhidi, Rob Krams

Department of Mechanical and Materials Engineering: Faculty Publications

This review provides an overview of the effect of blood flow on endothelial cell (EC) signalling pathways, applying microarray technologies to cultured cells, and in vivo studies of normal and atherosclerotic animals. It is found that in cultured ECs, 5–10% of genes are up- or down-regulated in response to fluid flow, whereas only 3–6% of genes are regulated by varying levels of fluid flow. Of all genes, 90%are regulated by the steady part of fluid flow and 10% by pulsatile components. The associated gene profiles show high variability from experiment to experiment depending on experimental conditions, and importantly, the bioinformatical …

Structural, Optical And Electrical Properties Of Yttrium-Doped Hafnium Oxide Nanocrystalline Thin Films, Abhilash Kongu

Open Access Theses & Dissertations

Hafnium oxide (HfO2) has emerged as the most promising high-k dielectric for Metal-Oxide-Semiconductor (MOS) devices and has been highlighted as the most suitable dielectric materials to replace silicon oxide because of its comprehensive performance. In the present research, yttrium-doped HfO2 (YDH) thin films were fabricated using RF magnetron sputter deposition onto Si (100) and quartz with a variable thickness. Cross-sectional scanning electron microscopy coupled with Filmetrics revealed that film thickness values range from 700 A° to 7500 A°. Electrical properties such as AC Resistivity and current-voltage (I-V) characteristics of YDH films were studied. YDH films that were relatively thin (<1500 A°) crystallized in monoclinic phase while thicker films crystallized in cubic phase. The band gap (Eg) of the films was calculated from the optical measurements. The band gap was found to be ∼5.60 eV for monoclinic while it is ∼6.05 eV for cubic phase of YDH films. Frequency dependence of the electrical resistivity (ρac) and the total conductivity of the films were measured. Resistivity decreased (by three orders of magnitude) with increasing frequency from 100 Hz to 1 MHz, attributed due to the hopping mechanism in YDH films. Whereas, while ρac∼1Ω-m at low frequencies (100 Hz), it decreased to ∼ 104 Ω-cm at higher frequencies (1 MHz). Aluminum (Al) metal electrodes were deposited to fabricate a thin film capacitor with YDH layer as dielectric film thereby employing Al-YDH-Si capacitor structure. The results indicate that the capacitance of the films decrease with increasing film thickness. A detailed analysis of the electrical characteristics of YDH films is presented.

Experimental Comparison Study Of The Response Of Polycarbonate And Laminated Glass Blast Resistant Glazing Systems To Blast Loading, Joshua Calnan

Theses and Dissertations--Mining Engineering

This thesis recounts the experimental study of the dynamic response of polycarbonate blast resistant glazing systems to explosive loading through the use of triaxial load cells, pressure sensors, and a laser displacement gauge. This instrumentation captured the response of the glazing systems to blast loading over three phases of testing. The first phase of testing characterizes the load distribution around the perimeter and the second phase examines the repeatability of the results. The final phase of testing pushes the samples to failure. The results are then compared to HazL, a commonly used blast resistant glazing system analysis software tool. The …

Analysis Of An Actuated Two Segment Leg Model Of Locomotion, Nikhil Vinayak Rao

Open Access Theses

Research studies on dynamic models of legged locomotion have generally focused on telescoping-type leg models. Such telescoping spring loaded inverted pendulum (SLIP) models have been able to accurately predict observed center of mass (CoM) trajectories. There have been comparatively fewer studies on dynamics of locomotion

with segmented legs. Some earlier studies on the dynamics due to leg segmentation appear straightforward. For example, a simple model with the only joint moment being due to a passive springy knee has been shown to behave similarly to a telescoping spring-mass model. However, in real-life animal locomotion, there are multiple joint-moments acting at the …

Orientation Controllable Epitaxial Vapor-Liquid-Solid Semiconductor Nanowire Synthesis On Silicon Substrate, Sung Hwan Chung

Open Access Dissertations

Semiconductor nanowires synthesized via the vapor-liquid-solid (VLS) mechanism have attracted extensive research interest in recent years owing to their unique structure as a promising candidate for the future electronic devices. Germanium and silicon nanowires, in particular, are compatible with the current silicon-based technology via direct assembly. However, one of the main challenges for the successful nanowire application in large-scale is the lack of the method for obtaining nanowires in desired positions and directions. Therefore, the comprehensive, systematic understanding of epitaxial nanowire growth and the more suitable method to align nanowires on novel structure are required. In this work, the synthesis …

Resolving Pronominal Anaphora Using Commonsense Knowledge, Seyedeh Leili Javadpour

LSU Doctoral Dissertations

Coreference resolution is the task of resolving all expressions in a text that refer to the same entity. Such expressions are often used in writing and speech as shortcuts to avoid repetition. The most frequent form of coreference is the anaphor. To resolve anaphora not only grammatical and syntactical strategies are required, but also semantic approaches should be taken into consideration. This dissertation presents a framework for automatically resolving pronominal anaphora by integrating recent findings from the field of linguistics with new semantic features. Commonsense knowledge is the routine knowledge people have of the everyday world. Because such knowledge is …

Non-Equilibrium Pressure Control Of The Height Of A Large-Scale, Ground-Coupled, Rotating Fluid Column, R. L. Ash, I. R. Zardadhkan

Mechanical & Aerospace Engineering Faculty Publications

When a ground-coupled, rotating fluid column is modeled incorporating non-equilibrium pressure forces in the Navier-Stokes equations, a new exact solution results. The solution has been obtained in a similar manner to the classical equilibrium solution. Unlike the infinite-height, classical solution, the non-equilibrium pressure solution yields a ground-coupled rotating fluid column of finite height. A viscous, non-equilibrium Rankine vortex velocity distribution, developed previously, was used to demonstrate how the viscous and non-equilibrium pressure gradient forces, arising in the vicinity of the velocity gradient discontinuity that is present in the classical Rankine vortex model, effectively isolate the rotating central fluid column from …

Microstructure And Mechanical Properties Of Titanium Nitride Optical Coatings Made By Dc Magnetron Sputtering, Gustavo Martinez

Open Access Theses & Dissertations

Titanium nitride (TiNx) thin films were grown by DC (Direct Current) magnetron sputtering method onto Si(100) substrates by varying time of deposition to produce films with variable thickness (dTiN) in the range of 20-120 nm. The grown TiNx films were characterized by studying their structure, composition, and mechanical properties. Nuclear reaction analysis (NRA) combined with Rutherford backscattering spectrometry (RBS) analyses indicate that the grown films were stoichiometric TiN. Grazing incidence X-ray diffraction (GIXRD) measurements indicate that the texturing of the TiN films changes as a function of dTiN. The (111) and (002) peaks appear initially; with increasing dTiN, (111) becomes …

Structure And Electronic Properties Of Pure And Nitrogen Doped Nanocrystalline Tungsten Oxide Thin Films, Vemnkata Rama Sesha Ravi Kumar Vemuri

Open Access Theses & Dissertations

Tungsten oxide (WO₃) is a multifunctional material which has applications in electronics, sensors, optoelectronics, and energy-related technologies. Recently, electronic structure modification of WO₃ to design novel photocatalysts has garnered significant attention. However, a fundamental understanding of nitrogen induced changes in the structure, morphology, surface/interface chemistry, and electronic properties of WO₃ is a prerequisite to producing materials with the desired functionality and performance. Also, understanding the effect of thermodynamic and processing variables is highly desirable in order to derive the structure-property relationships in the W-O/W-O-N material system. The present work was, therefore, focused on studying the effects …

Design Flood Elevations Beyond Code Requirements And Current Best Practices, Frank H. Bohn

LSU Master's Theses

In the United States, nearly 9 million people, 3.0% of the population, live in areas subject to the 1% annual chance (100-yr) coastal flood hazard. New construction and substantial improvements in coastal high hazard areas require structures to be elevated above the design flood elevation (DFE), without the use of fill (Bellomo et al. 1999). Building code requirements for flood elevation are linked to the National Flood Insurance Program (NFIP) insurance policies, and represent the minimum requirement for building elevation. Current elevation procedures are limited to the 100-year base flood elevation with minimal guidance beyond the 100-year elevation in many …

Investigation Of Best Practices For Maintenance Of Concrete Bridge Railings, Angel Luis Lence

LSU Master's Theses

Biodeterioration on concrete surfaces of vertical elements of bridges represents a serious challenge to the highway infrastructure in Louisiana. This investigation aims to document the causes of biodeterioration of concrete surfaces and to document current conventional and state-of-the-art practices implemented to prevent and clean biofilm. A comprehensive literature review of previous research has been carried out in order to determine the cause and mechanisms of the biodeterioration as well as to identify current methods that state DOTs have implemented in order to maintain their bridges and allow them to function in optimal structural and performance conditions. A survey was developed …

Controversy Trend Detection In Social Media, Rajshekhar Vishwanath Chimmalgi

LSU Master's Theses

In this research, we focus on the early prediction of whether topics are likely to generate significant controversy (in the form of social media such as comments, blogs, etc.). Controversy trend detection is important to companies, governments, national security agencies, and marketing groups because it can be used to identify which issues the public is having problems with and develop strategies to remedy them. For example, companies can monitor their press release to find out how the public is reacting and to decide if any additional public relations action is required, social media moderators can moderate discussions if the discussions …

Automated Semantic Content Extraction From Images, Mahdi Arab Khazaeli

LSU Doctoral Dissertations

In this study, an automatic semantic segmentation and object recognition methodology is implemented which bridges the semantic gap between low level features of image content and high level conceptual meaning. Semantically understanding an image is essential in modeling autonomous robots, targeting customers in marketing or reverse engineering of building information modeling in the construction industry. To achieve an understanding of a room from a single image we proposed a new object recognition framework which has four major components: segmentation, scene detection, conceptual cueing and object recognition. The new segmentation methodology developed in this research extends Felzenswalb's cost function to include …

Reducing Metal Alloy Powder Costs For Use In Powder Bed Fusion Additive Manufacturing: Improving The Economics For Production, Fransisco Medina

Open Access Theses & Dissertations

Titanium and its associated alloys have been used in industry for over 50 years and have become more popular in the recent decades. Titanium has been most successful in areas where the high strength to weight ratio provides an advantage over aluminum and steels. Other advantages of titanium include biocompatibility and corrosion resistance. Electron Beam Melting (EBM) is an additive manufacturing (AM) technology that has been successfully applied in the manufacturing of titanium components for the aerospace and medical industry with equivalent or better mechanical properties as parts fabricated via more traditional casting and machining methods. As the demand for …

Crystal Structure, Phase, And Optical Properties Of Yttrium-Doped Hafnium Oxide Nanocrystalline Thin Films, Alejandro Ortega

Open Access Theses & Dissertations

Yttrium-doped hafnium oxide (YDH) nanocrystalline films were produced by sputter-deposition at various substrate times and temperatures, to produce YDH films in a wide range of thicknesses, dYDH∼25 to 1100 nm. The deposition was made onto optical grade quartz and sapphire substrates. Samples deposited on sapphire were subject to post-deposition annealing (PDA) at various times (3-24 hr) and temperatures (1100 - 1500 °C). The effect of d[special characters omitted]YDH on the crystal structure, surface/interface morphology and optical properties of YDH films was investigated. X-ray diffraction analyses revealed the formation of monoclinic phase for relatively thin films (<150nm). The evolution towards stabilized cubic phase with increasing dYDH [special characters omitted]is observed. The scanning electron microscopy results indicate the dense, columnar structure of YDH films as a function of dYDH. Spectrophotometry analyses indicate that the grown YDH films are transparent and exhibit interference fringes. The band gap was found to be ∼ 5.60 eV for monoclinic YDH films while distinct separation and an increase in band gap to 6.03 eV is evident with increasing dYDH and formation cubic YDH films. The PDA films band gaps were found to be between 5.31 and 5.72 eV, all of which exhibit secondary gaps. A correlation between growth conditions, annealing, phase evolution, and optical properties of the YDH nanocrystalline thin films is established.

Comparative Characterization Of Ni-Base Superalloys Fabricated By Laser And Electron Beam Melting Technologies, Krista Amato

Open Access Theses & Dissertations

Nickel-base superalloys have been used in cast and wrought, and powder metallurgy forms for nearly four decades for industrial and automotive applications. One drawback of cast alloys is that upon solidification, there is minimal microstructural control. Another issue to be improved is to eliminate the limitations of shapes and forms of fabricated alloys.

Rapid prototyping is a new technology of additive manufacturing that shows to be promising for the freeform fabrication of novel superalloys, including nickel-base alloys. New rapid manufacturing technologies allow us to produce parts in any shape that can be designed by computer-aided design (CAD) software. Additionally, the …

The Investigation Of Valve Operators' Torque Production Capabilities And Optimal Handwheel Height, Angle, And Opening Technique, Saif K. Al-Qaisi

LSU Doctoral Dissertations

This research consists of two projects concerned with handwheel-valve operations. The objectives of poject-1 were to: (1) introduce an ergonomically-modified valve-wrench and compare it to conventional valve-opening methods, in terms of efficiency (time to open valve), perceived physical exertion (Borg-scale), and muscle loading of shoulder and trunk muscles; and (2) determine whether the torque setting (15 Nm and 30 Nm) of the valve affects the preferred valve-opening method. Four methods were evaluated, including using bare hands (BH), conventional wrench-restricted (CW-R, assumes presence of obstructions), conventional wrench-unrestricted (CW-U, assumes no obstructions), and modified wrench (MW). Electromyography (EMG) activities were measured from …

Optimal Consignment Stocking Policies For A Supply Chain Under Different System Constraints, Hui Zhi Yi

LSU Doctoral Dissertations

The research aims are to enable the decision maker of an integrated vendor-buyer system under Consignment Stock (CS) policy to make the optimal/sub-optimal production/replenishment decisions when some general and realistic critical factors are considered. In the system, the vendor produces one product at a finite rate and ships the outputs by a number of equal-sized lots within a production cycle. Under a long-term CS agreement, the vendor maintains a certain inventory level at the buyer’s warehouse, and the buyer compensates the vendor only for the consumed products. The holding cost consists of a storage component and a financial component. Moreover, …

Microstructure And Physics-Based Structural Models For Suspended Clay-Exopolymer Flocs, Xiaoling Tan

LSU Doctoral Dissertations

Costal or shoreline waters are often characterized by high concentrations of suspended cohesive sediments (or clay) affected by varied organic matters (mostly extracellular polymeric substances or exopolymers), salt, and hydrodynamic disturbance. Resulting from the flocculation-disaggregation between the colloidal clay and exopolymer, the size and structure changes of the cohesive sediments are of key importance for understanding sediment transport processes (i.e., settling, breakage, and survivability) and the geotechnical and geophysical properties of the bottom bed. Because the coastal environment is extremely complicated, with many unpredictable and uncontrollable parameters, current knowledge is still insufficient to predict or fully explain the behavior of …

Process Study And Control Of Electron Beam Melting Technology Using Infrared Thermography, Jorge Mireles

Open Access Theses & Dissertations

An IR camera was installed in an Arcam A2 system (Arcam AB, Mölndal, Sweeden) and layer-by-layer image acquisition was achieved. The camera's capability to detect manufacturing defects was evaluated by implementing computer vision techniques using LabVIEW measurement and programming software (National Instruments, Austin, TX). Thermal maps acquired by the IR camera allowed layer-by-layer part temperature to be recorded. A core objective of this research was to study the impact of processing temperature on EBM-fabricated Ti-6Al-4V parts and achieve controlled mechanical properties. In this research, build variations were achieved by modifying parameters that change processing temperature from the standard processing temperature. …