Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, 2024 Wilfrid Laurier University
Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen
Theses and Dissertations (Comprehensive)
The complex nature of the human brain, with its intricate organic structure and multiscale spatio-temporal characteristics ranging from synapses to the entire brain, presents a major obstacle in brain modelling. Capturing this complexity poses a significant challenge for researchers. The complex interplay of coupled multiphysics and biochemical activities within this intricate system shapes the brain's capacity, functioning within a structure-function relationship that necessitates a specific mathematical framework. Advanced mathematical modelling approaches that incorporate the coupling of brain networks and the analysis of dynamic processes are essential for advancing therapeutic strategies aimed at treating neurodegenerative diseases (NDDs), which afflict millions of …
Reducing Food Scarcity: The Benefits Of Urban Farming, 2023 Brigham Young University
Reducing Food Scarcity: The Benefits Of Urban Farming, S.A. Claudell, Emilio Mejia
Journal of Nonprofit Innovation
Urban farming can enhance the lives of communities and help reduce food scarcity. This paper presents a conceptual prototype of an efficient urban farming community that can be scaled for a single apartment building or an entire community across all global geoeconomics regions, including densely populated cities and rural, developing towns and communities. When deployed in coordination with smart crop choices, local farm support, and efficient transportation then the result isn’t just sustainability, but also increasing fresh produce accessibility, optimizing nutritional value, eliminating the use of ‘forever chemicals’, reducing transportation costs, and fostering global environmental benefits.
Imagine Doris, who is …
Aspects Of Stochastic Geometric Mechanics In Molecular Biophysics, 2023 Clemson University
Aspects Of Stochastic Geometric Mechanics In Molecular Biophysics, David Frost
All Dissertations
In confocal single-molecule FRET experiments, the joint distribution of FRET efficiency and donor lifetime distribution can reveal underlying molecular conformational dynamics via deviation from their theoretical Forster relationship. This shift is referred to as a dynamic shift. In this study, we investigate the influence of the free energy landscape in protein conformational dynamics on the dynamic shift by simulation of the associated continuum reaction coordinate Langevin dynamics, yielding a deeper understanding of the dynamic and structural information in the joint FRET efficiency and donor lifetime distribution. We develop novel Langevin models for the dye linker dynamics, including rotational dynamics, based …
Experimental Analysis Of Nonlinear Wave Propagation In Bistable Mechanical Metamaterials With A Defect, 2023 University of Nebraska-Lincoln
Experimental Analysis Of Nonlinear Wave Propagation In Bistable Mechanical Metamaterials With A Defect, Samuel R. Harre
Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research
Mechanical metamaterials built up of compliant units can support the propagation of linear and nonlinear waves. A popular architecture consists of a one-dimensional chain of bistable elements connected by linear springs. This type of chain can support nonlinear transition waves that switch each element from one stable state to the other as they propagate along the chain. One way to manipulate the propagation of such waves is via introduction of a local inhomogeneity, i.e., a defect in the otherwise periodic chain. Recent analytical and numerical work has shown that based on its initial velocity, a transition wave may be reflected, …
Controlled Manipulation And Transport By Microswimmers In Stokes Flows, 2023 Clemson University
Controlled Manipulation And Transport By Microswimmers In Stokes Flows, Jake Buzhardt
All Dissertations
Remotely actuated microscale swimming robots have the potential to revolutionize many aspects of biomedicine. However, for the longterm goals of this field of research to be achievable, it is necessary to develop modelling, simulation, and control strategies which effectively and efficiently account for not only the motion of individual swimmers, but also the complex interactions of such swimmers with their environment including other nearby swimmers, boundaries, other cargo and passive particles, and the fluid medium itself. The aim of this thesis is to study these problems in simulation from the perspective of controls and dynamical systems, with a particular focus …
Dynamic Rotation Of Maxwellian Fluid With Fluctuating Thermal Conductivity, 2023 Department of Mathematics, University of Wah, Wah Cantt 47040, Pakistan
Dynamic Rotation Of Maxwellian Fluid With Fluctuating Thermal Conductivity, Yasir Iqbal, Iqra Batool, Zia Ur Rehman
International Journal of Emerging Multidisciplinaries: Mathematics
This investigation examined the behavior of an overhead-connected Maxwell (UCM) fluid within a rotating framework, with consideration for variations in thermal conductivity based on temperature. The heat deportation process was simulated by incorporating a non-Fourier heat flux term, accounting for thermal relaxation effects. The governing set of partial differential equations underwent decomposition through boundary layer approximations, followed by employing similarity transformations to convert them into self-similar forms. To investigate the effect of the rotation criterion ($\lambda$), Prandtl number (Pr), Deborah number ($\beta$), parameter ($\epsilon$), and dimensionless thermal relaxation time ($\gamma$), an advanced three-stage Lobatto IIIa numerical method was applied. The …
Thermodynamic Laws Of Billiards-Like Microscopic Heat Conduction Models, 2023 University of Massachusetts Amherst
Thermodynamic Laws Of Billiards-Like Microscopic Heat Conduction Models, Ling-Chen Bu
Doctoral Dissertations
In this thesis, we study the mathematical model of one-dimensional microscopic heat conduction of gas particles, applying both both analytical and numerical approaches. The macroscopic law of heat conduction is the renowned Fourier’s law J = −k∇T, where J is the local heat flux density, T(x, t) is the temperature gradient, and k is the thermal conductivity coefficient that characterizes the material’s ability to conduct heat. Though Fouriers’s law has been discovered since 1822, the thorough understanding of its microscopic mechanisms remains challenging [3] (2000). We assume that the microscopic model of heat conduction is a hard ball system. The …
Utilizing Non-Negative Least Squares For Data-Driven Discovery Of Dynamics, 2023 George Mason University
Utilizing Non-Negative Least Squares For Data-Driven Discovery Of Dynamics, Tracey G. Oellerich
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Computational Modeling Using A Novel Continuum Approach Coupled With Pathway-Informed Neural Networks To Optimize Dynein-Mediated Centrosome Positioning In Polarized Cells, 2023 George Mason University
Computational Modeling Using A Novel Continuum Approach Coupled With Pathway-Informed Neural Networks To Optimize Dynein-Mediated Centrosome Positioning In Polarized Cells, Arkaprovo Ghosal, Padmanabhan Seshaiyar Dr., Adriana Dawes Dr., General Genomics Inc.
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Using A Coupled Integral Projection Model To Investigate Interspecific Competition During An Invasion: An Application To Silver Carp (Hypophthalmichthys Molitrix) And Gizzard Shad (Dorosoma Cepedianum), 2023 Illinois State University
Using A Coupled Integral Projection Model To Investigate Interspecific Competition During An Invasion: An Application To Silver Carp (Hypophthalmichthys Molitrix) And Gizzard Shad (Dorosoma Cepedianum), James Peirce
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Critical Transitions In Mental Health: Van Gogh Case Study, 2023 University of Portland
Critical Transitions In Mental Health: Van Gogh Case Study, Anna Singley
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Effects Of Seasonal Birth And Predation On Disease Spread, 2023 William & Mary
Effects Of Seasonal Birth And Predation On Disease Spread, Leah Shaw, Allison Introne
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Epidemic Conditions With Temporary Link Deactivation On A Network Sir Disease Model, 2023 Illinois State University
Epidemic Conditions With Temporary Link Deactivation On A Network Sir Disease Model, John Gemmer
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Msis-Kadelka: Modularizing The Control Search For Biological Systems, 2023 University of Kentucky
Msis-Kadelka: Modularizing The Control Search For Biological Systems, David Murrugarra
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Msis-Kadelka: Canalization Reduces The Nonlinearity Of Regulation In Biological Networks, 2023 University of Kentucky
Msis-Kadelka: Canalization Reduces The Nonlinearity Of Regulation In Biological Networks, Claus Kadelka, David Murrugarra
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling The Communication Dynamics In Human-Autonomy Teams: Insights From Search And Rescue Scenarios, 2023 Arizona State University at the Tempe Campus
Modeling The Communication Dynamics In Human-Autonomy Teams: Insights From Search And Rescue Scenarios, Carlos E. Bustamante Orellana, Lucero Rodriguez Rodriguez, Yun Kang
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Study Of Behaviour Change And Impact On Infectious Disease Dynamics By Mathematical Models, 2023 The University of Western Ontario
Study Of Behaviour Change And Impact On Infectious Disease Dynamics By Mathematical Models, Tianyu Cheng
Electronic Thesis and Dissertation Repository
This thesis uses mathematical models to study human behaviour changes' effects on infectious disease transmission dynamics. It centers on two main topics. The first concerns how behaviour response evolves during epidemics and the effects of adaptive precaution behaviour on epidemics. The second topic is how to build general framework models incorporating human behaviour response in epidemiological modelling.
In the first project, based on the fact that a fraction of the epidemiologically susceptible population is actually susceptible due to precautions, we present a novel perspective on understanding the infection force, incorporating human protection behaviours. This view explains many existing infection force …
Rigid Body Constrained Motion Optimization And Control On Lie Groups And Their Tangent Bundles, 2023 Embry-Riddle Aeronautical University
Rigid Body Constrained Motion Optimization And Control On Lie Groups And Their Tangent Bundles, Brennan S. Mccann
Doctoral Dissertations and Master's Theses
Rigid body motion requires formulations where rotational and translational motion are accounted for appropriately. Two Lie groups, the special orthogonal group SO(3) and the space of quaternions H, are commonly used to represent attitude. When considering rigid body pose, that is spacecraft position and attitude, the special Euclidean group SE(3) and the space of dual quaternions DH are frequently utilized. All these groups are Lie groups and Riemannian manifolds, and these identifications have profound implications for dynamics and controls. The trajectory optimization and optimal control problem on Riemannian manifolds presents significant opportunities for theoretical development. Riemannian optimization is an attractive …
Pathogen Emergence As Complex Biological Invasion: Lessons From Dynamical Systems Modeling, 2023 Yale University
Pathogen Emergence As Complex Biological Invasion: Lessons From Dynamical Systems Modeling, Sudam Surasinghe, Marisabel Rodriguez, Victor Meszaros, Jane Molofsky, Salvador Almagro-Moreno, Brandon Ogbunugafor
Northeast Journal of Complex Systems (NEJCS)
Infectious disease emergence has become the target of cross-disciplinary efforts
that aim to understand and predict the shape of outbreaks. The many challenges
involved with the prediction of disease emergence events is a characteristic that in-
fectious diseases share with biological invasions in many subfields of ecology (e.g.,
how certain plants are able to successfully invade a new niche). Like infectious
diseases, biological invasions by plants and animals involve interactions between
agents (pathogens and plants in their respective cases) and a recipient niche. In
this study, we examine the problem of pathogen emergence through the lens of a
framework first …
Temporality-Induced Chaos In The Kuramoto Model, 2023 Toronto Metropolitan University, Toronto, Canada
Temporality-Induced Chaos In The Kuramoto Model, Keanu Mason Rock, Hamza Dirie, Sean P. Cornelius
Northeast Journal of Complex Systems (NEJCS)
Switched dynamical systems have been extensively studied in engineering literature in the context of system control. In these systems, the dynamical laws change between different subsystems depending on the environment, a process that is known to produce emergent behaviors---notably chaos. These dynamics are analogous to those of temporal networks, in which the network topology changes over time, thereby altering the dynamics on the network. It stands to reason that temporal networks may therefore produce emergent chaos and other exotic behaviors unanticipated in static networks, yet concrete examples remain elusive. Here, we present a minimal example of a networked system in …