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Clozapine For Treatment-Resistant Bipolar Disorder: A Systematic Review, Xian-Bin Li, Yi-Lang Tang, Chuan-Yue Wang, Jose de Leon 2015 Capital Medical University, China

Clozapine For Treatment-Resistant Bipolar Disorder: A Systematic Review, Xian-Bin Li, Yi-Lang Tang, Chuan-Yue Wang, Jose De Leon

Psychiatry Faculty Publications

Objective

To evaluate the efficacy and safety of clozapine for treatment-resistant bipolar disorder (TRBD).

Methods

A systematic review of randomized controlled studies, open-label prospective studies, and retrospective studies of patients with TRBD was carried out. Interventions included clozapine monotherapy or clozapine combined with other medications. Outcome measures were efficacy and adverse drug reactions (ADRs).

Results

Fifteen clinical trials with a total sample of 1,044 patients met the inclusion criteria. Clozapine monotherapy or clozapine combined with other treatments for TRBD was associated with improvement in: (i) symptoms of mania, depression, rapid cycling, and psychotic symptoms, with many patients with TRBD ...


Caffeine Consumption In A Long-Term Psychiatric Hospital: Tobacco Smoking May Explain In Large Part The Apparent Association Between Schizophrenia And Caffeine Use, Manuel Arrojo-Romero, Carmen Armas Barbazán, Javier D. López-Moriñigo, Ramón Ramos-Rios, Manuel Gurpegui, José M. Martinez-Ortega, Dolores Jurado, Francisco J. Diaz, Jose de Leon 2015 Gallegan Health System, Spain

Caffeine Consumption In A Long-Term Psychiatric Hospital: Tobacco Smoking May Explain In Large Part The Apparent Association Between Schizophrenia And Caffeine Use, Manuel Arrojo-Romero, Carmen Armas Barbazán, Javier D. López-Moriñigo, Ramón Ramos-Rios, Manuel Gurpegui, José M. Martinez-Ortega, Dolores Jurado, Francisco J. Diaz, Jose De Leon

Psychiatry Faculty Publications

This study further explores the association between schizophrenia and caffeine use by combining two prior published Spanish samples (250 schizophrenia outpatients and 290 controls from the general population) with two Spanish long-term inpatient samples from the same hospital (145 with schizophrenia and 64 with other severe mental illnesses). The specific aims were to establish whether or not, after controlling for confounders including tobacco smoking, the association between schizophrenia and caffeine is consistent across schizophrenia samples and across different definitions of caffeine use. The frequency of caffeine use in schizophrenia inpatients was not significantly higher than that in non-schizophrenia inpatients (77 ...


The Flip-Side To Readmission: Focused After-Care, Amresh Srivastava 2015 University of Western Ontario

The Flip-Side To Readmission: Focused After-Care, Amresh Srivastava

Amresh Srivastava

paper 1. Suicidality in hospitalized early psychosis patients at time of discharge

The purpose of this study was to investigate the presence and nature of suicidal risk among early psychosis patients at the time of discharge from hospital. Is it only related to the involvement of a suicidal attempt at admission? Thirty such patients, who were admitted after a suicide attempt were compared with 30 patients similarly diagnosed, but admitted for clinical reasons not involving a suicide attempt. Dependent measures of psychopathology, adjustment and suicidality were used. It was found that the two groups did not differ in suicidality, which ...


Assessment Practices For Undergraduate Psychology: A Model Perspective, R. Landrum, Maureen McCarthy 2015 Boise State University

Assessment Practices For Undergraduate Psychology: A Model Perspective, R. Landrum, Maureen Mccarthy

R. Eric Landrum

More than one million students earned a bachelor's degree in psychology over the course of the past 13 years, and the popularity of psychology as an undergraduate degree continues to grow. If the number of students majoring in psychology continues to increase at comparable rates, an additional one million psychology majors will graduate over the course of the next decade (National Center for Education Statistics, 2011). In other words, our graduates, armed with scientific reasoning skills (Halonen, Bosack, Clay, & McCarthy, 2003) will be psychologically literate citizens positioned to convey the core elements of the discipline to the larger population ...


Assessment And The Scholarship Of Teaching And Learning, Regan Gurung, R. Landrum 2015 University of Wisconsin-Green Bay

Assessment And The Scholarship Of Teaching And Learning, Regan Gurung, R. Landrum

R. Eric Landrum

Assessment is at the core of the scholarship of teaching and learning (SoTL). In fact, the debate on what exactly constitutes SoTL (e.g., McKinney, 2007; Pan, 2009) often hinges on whether or not student learning is assessed together with whether the results are published or not. Is my teaching effective? Are my students learning? How do I know? Ask these questions of a department, program, college or university, and it is clear you are talking about assessment, a "global term used to refer to the authentic evaluation of teaching and learning outcomes" (Dunn, McCarthy, Baker, Halonen, & Boyer, 2011, p.145). In our view, assessment is the centerpiece to SoTL and maintaining a student-centered focus. Others appear to agree as well (Maki, 2010; Potter & Kustra, 2011). Another definition of assessment involves "the systematic collection of information about student learning, using the time, knowledge, expertise, and resources available, in order to inform decisions about how to improve learning" (Walvoord, 2004, p.2; italics in ...


Genomic And Clinical Effects Associated With A Relaxation Response Mind-Body Intervention In Patients With Irritable Bowel Syndrome And Inflammatory Bowel Disease, Braden Kuo, Manoj Bhasin, Jolene Jacquart, Matthew A. Scult, Lauren Slipp, Eric Isaac Riklin Kagan, Veronique Lepoutre, Nicole Comosa, Beth-Ann Norton, Allison Dassatti, Jessica Rosenblum, Andrea H. Thurler, Brian C. Surjanhata, Nicole N. Hasheminejad, Leslee Kagan, Ellen Slawsby, Sowmya R. Rao, Eric A. Macklin, Gregory L. Fricchione, Herbert Benson, Towia A. Libermann, Joshua Korzenik, John W. Denninger 2015 Massachusetts General Hospital

Genomic And Clinical Effects Associated With A Relaxation Response Mind-Body Intervention In Patients With Irritable Bowel Syndrome And Inflammatory Bowel Disease, Braden Kuo, Manoj Bhasin, Jolene Jacquart, Matthew A. Scult, Lauren Slipp, Eric Isaac Riklin Kagan, Veronique Lepoutre, Nicole Comosa, Beth-Ann Norton, Allison Dassatti, Jessica Rosenblum, Andrea H. Thurler, Brian C. Surjanhata, Nicole N. Hasheminejad, Leslee Kagan, Ellen Slawsby, Sowmya R. Rao, Eric A. Macklin, Gregory L. Fricchione, Herbert Benson, Towia A. Libermann, Joshua Korzenik, John W. Denninger

Open Access Articles

INTRODUCTION: Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD) can profoundly affect quality of life and are influenced by stress and resiliency. The impact of mind-body interventions (MBIs) on IBS and IBD patients has not previously been examined.

METHODS: Nineteen IBS and 29 IBD patients were enrolled in a 9-week relaxation response based mind-body group intervention (RR-MBI), focusing on elicitation of the RR and cognitive skill building. Symptom questionnaires and inflammatory markers were assessed pre- and post-intervention, and at short-term follow-up. Peripheral blood transcriptome analysis was performed to identify genomic correlates of the RR-MBI.

RESULTS: Pain Catastrophizing Scale scores ...


Measuring Patient Experience In A Safety Net Setting: Lessons Learned, Nina Shabbat, Katy Dobbins, Sonja Seglin, Kristin Davis 2015 Thresholds

Measuring Patient Experience In A Safety Net Setting: Lessons Learned, Nina Shabbat, Katy Dobbins, Sonja Seglin, Kristin Davis

Patient Experience Journal

Safety net providers have faced barriers in administering patient experience surveys due to a lack of resources and survey expertise, but this problem has received little attention in the literature. In this manuscript, we offer lessons learned from the administration of a patient experience survey at a mid-size behavioral health care agency serving a safety net population. Specifically, we discuss resource needs, methods of increasing response rate among transient populations, methods for engaging stakeholders and clinical staff in quality improvement initiatives, and considerations for responding to setbacks and challenges dynamically. We also offer insight on the effective dissemination of results ...


Pregnancy Intention In Relation To Nonplanning Impulsivity, Prachi Godiwala, Bradley M. Appelhans, Tiffany A. Moore Simas, Rui Sherry Xiao, Kathryn E. Liziewski, Sherry L. Pagoto, Molly E. Waring 2015 University of Massachusetts Medical School

Pregnancy Intention In Relation To Nonplanning Impulsivity, Prachi Godiwala, Bradley M. Appelhans, Tiffany A. Moore Simas, Rui Sherry Xiao, Kathryn E. Liziewski, Sherry L. Pagoto, Molly E. Waring

Senior Scholars Program

Introduction: Half of pregnancies in the United States are unintended. We examine a novel risk factor for unintended pregnancies, impulsivity. We hypothesize that women with higher nonplanning impulsivity will be more likely to have an unplanned pregnancy.

Methods: The parent study was a prospective cohort study of 125 pregnant women examining the association between impulsivity and weight gain during pregnancy. At an in-person study visit, women completed self-report measures via a secure web form. The 15-item Barratt Impulsiveness Scale (BIS-15) measures impulsivity using subjective statements about the respondent’s behavior with 4 response options: rarely/never, occasionally, often, and almost ...


Are Apes’ Responses To Pointing Gestures Intentional?, Olivia Sultanescu, Kristin Andrews 2015 York University

Are Apes’ Responses To Pointing Gestures Intentional?, Olivia Sultanescu, Kristin Andrews

Kristin Andrews, Ph.D.

This paper examines the meaningfulness of pointing in great apes. We appeal to Hannah Ginsborg’s conception of primitive normativity, which provides an adequate criterion for establishing whether a response is meaningful, and we attempt to make room for a conception according to which there is no fundamental difference between the responses of human infants and those of other great apes to pointing gestures. This conception is an alternative to Tomasello’s view that pointing gestures and reactions to them reveal a fundamental difference between humans and other apes.


Writing In Apa Style: Faculty Perspectives Of Competence And Importance, R. Landrum 2015 Boise State University

Writing In Apa Style: Faculty Perspectives Of Competence And Importance, R. Landrum

R. Eric Landrum

A US sample (N = 360) of psychology educators assessed 73 writing skills and competencies with regard to (a) the importance of each and (b) the typical performance of the top half of local psychology majors. An analysis of gap scores yielded results showing that specific skills, such as supporting claims with citations and proofreading ability, are areas in need of greater emphasis and renewed pedagogical attention by instructors. Educators may use the results of this study to help to identify areas of increased need for writing instruction regarding undergraduate psychology education.


Is Latency To Test Deadline A Predictor Of Student Test Performance?, R. Landrum, Regan Gurung 2015 Boise State University

Is Latency To Test Deadline A Predictor Of Student Test Performance?, R. Landrum, Regan Gurung

R. Eric Landrum

When students are given a period or window of time to take an exam, is taking an exam earlier in the window (high latency to deadline) related to test scores? In Study 1, students (n = 236) were given windows of time to take online each of 13 quizzes and 4 exams. In Study 2, students (n = 251) similarly took 4 exams online within a test window. In both studies, latency to deadline was significantly correlated to exam score. Higher scoring students took the exam earlier in the test window. We explore possible explanations of these relationships and map out directions ...


Influence Of The Hcr-20, Ls/Cmi, And Pcl-R On Decisions About Parole Suitability Among Lifers, Laura Guy, Cliff Kusaj, Ira Packer, Kevin Douglas 2015 University of Massachusetts Medical School

Influence Of The Hcr-20, Ls/Cmi, And Pcl-R On Decisions About Parole Suitability Among Lifers, Laura Guy, Cliff Kusaj, Ira Packer, Kevin Douglas

Ira K Packer

Among 5,181 inmates indeterminately sentenced to life in California who were evaluated for parole suitability between January 2009 and November 2010, 11% were granted parole. After administration of the HCR-20, LS/CMI, and PCL-R, psychologists judged most inmates (78%) to be at low or moderate risk for future violence. This overall risk rating (ORR) was significantly associated with parole suitability decisions. Moderate to large associations were observed between the ORR and all risk indices. The HCR-20 Clinical and Risk Management scales demonstrated the strongest associations with parole suitability decisions. Among the LS/CMI scales, Procriminal Attitudes and Leisure/Recreation ...


Latent Variable Approaches For Understanding Heterogeneity In Depression: A Dissertation, Christine M. Ulbricht 2015 University of Massachusetts Medical School

Latent Variable Approaches For Understanding Heterogeneity In Depression: A Dissertation, Christine M. Ulbricht

GSBS Dissertations and Theses

Background: Major depression is one of the most prevalent, disabling, and costly illnesses worldwide. Despite a 400% increase in antidepressant medication use since 1988, fewer than half of treated depression patients experience a clinically meaningful reduction in symptoms and uncertainty exists regarding how to successfully obtain symptom remission. Identifying homogenous subgroups based on clinically observable characteristics could improve the ability to efficiently predict who will benefit from which treatments.

Methods: Latent class analysis and latent transition analysis (LTA) were applied to data from the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study to explore how to efficiently identify subgroups ...


Prevalence Of Attention-Deficit/ Hyperactivity Disorder: A Systematic Review And Meta-Analysis, Rae Thomas, Sharon Sanders, Jenny Doust, Elaine Beller, Paul Glasziou 2015 Bond University

Prevalence Of Attention-Deficit/ Hyperactivity Disorder: A Systematic Review And Meta-Analysis, Rae Thomas, Sharon Sanders, Jenny Doust, Elaine Beller, Paul Glasziou

Paul Glasziou

Overdiagnosis and underdiagnosis of attention-deficit/hyperactivity abstract disorder (ADHD) are widely debated, fueled by variations in prevalence estimates across countries, time, and broadening diagnostic criteria. We conducted a meta-analysis to: establish a benchmark pooled prevalence for ADHD; examine whether estimates have increased with publication of different editions of the Diagnostic and Statistical Manual of Mental Disorders (DSM); and explore the effect of study features on prevalence. METHODS: Medline, PsycINFO, CINAHL, Embase, and Web of Science were searched for studies with point prevalence estimates of ADHD. We included studies of children that used the diagnostic criteria from DSM-III, DSM-III-R and DSM-IV ...


Prevalence Of Attention-Deficit/ Hyperactivity Disorder: A Systematic Review And Meta-Analysis, Rae Thomas, Sharon Sanders, Jenny Doust, Elaine Beller, Paul Glasziou 2015 Bond University

Prevalence Of Attention-Deficit/ Hyperactivity Disorder: A Systematic Review And Meta-Analysis, Rae Thomas, Sharon Sanders, Jenny Doust, Elaine Beller, Paul Glasziou

Rae Thomas

Overdiagnosis and underdiagnosis of attention-deficit/hyperactivity abstract disorder (ADHD) are widely debated, fueled by variations in prevalence estimates across countries, time, and broadening diagnostic criteria. We conducted a meta-analysis to: establish a benchmark pooled prevalence for ADHD; examine whether estimates have increased with publication of different editions of the Diagnostic and Statistical Manual of Mental Disorders (DSM); and explore the effect of study features on prevalence. METHODS: Medline, PsycINFO, CINAHL, Embase, and Web of Science were searched for studies with point prevalence estimates of ADHD. We included studies of children that used the diagnostic criteria from DSM-III, DSM-III-R and DSM-IV ...


Prevalence Of Attention-Deficit/ Hyperactivity Disorder: A Systematic Review And Meta-Analysis, Rae Thomas, Sharon Sanders, Jenny Doust, Elaine Beller, Paul Glasziou 2015 Bond University

Prevalence Of Attention-Deficit/ Hyperactivity Disorder: A Systematic Review And Meta-Analysis, Rae Thomas, Sharon Sanders, Jenny Doust, Elaine Beller, Paul Glasziou

Jenny Doust

Overdiagnosis and underdiagnosis of attention-deficit/hyperactivity abstract disorder (ADHD) are widely debated, fueled by variations in prevalence estimates across countries, time, and broadening diagnostic criteria. We conducted a meta-analysis to: establish a benchmark pooled prevalence for ADHD; examine whether estimates have increased with publication of different editions of the Diagnostic and Statistical Manual of Mental Disorders (DSM); and explore the effect of study features on prevalence. METHODS: Medline, PsycINFO, CINAHL, Embase, and Web of Science were searched for studies with point prevalence estimates of ADHD. We included studies of children that used the diagnostic criteria from DSM-III, DSM-III-R and DSM-IV ...


Prevalence Of Attention-Deficit/ Hyperactivity Disorder: A Systematic Review And Meta-Analysis, Rae Thomas, Sharon Sanders, Jenny Doust, Elaine Beller, Paul Glasziou 2015 Bond University

Prevalence Of Attention-Deficit/ Hyperactivity Disorder: A Systematic Review And Meta-Analysis, Rae Thomas, Sharon Sanders, Jenny Doust, Elaine Beller, Paul Glasziou

Elaine Beller

Overdiagnosis and underdiagnosis of attention-deficit/hyperactivity abstract disorder (ADHD) are widely debated, fueled by variations in prevalence estimates across countries, time, and broadening diagnostic criteria. We conducted a meta-analysis to: establish a benchmark pooled prevalence for ADHD; examine whether estimates have increased with publication of different editions of the Diagnostic and Statistical Manual of Mental Disorders (DSM); and explore the effect of study features on prevalence. METHODS: Medline, PsycINFO, CINAHL, Embase, and Web of Science were searched for studies with point prevalence estimates of ADHD. We included studies of children that used the diagnostic criteria from DSM-III, DSM-III-R and DSM-IV ...


Challenges To Research In Urban Community Health Centers, Stephenie Lemon, Jane Zapka, Barbara Estabrook, Evan Benjamin 2015 University of Massachusetts Medical School

Challenges To Research In Urban Community Health Centers, Stephenie Lemon, Jane Zapka, Barbara Estabrook, Evan Benjamin

Evan Benjamin MD

Community health centers (CHCs) are important settings for research aimed at reducing health disparities. However, CHCs pose many challenges to research at patient, provider, and system levels. We summarized lessons learned from a multimethod, formative study to develop intervention strategies for improving colorectal cancer screening in CHCs, and make recommendations for future research. The call for research in "real world" settings such as CHCs must be matched with greater understanding of the challenges, as well as the resources to meet those challenges.


Experience Of Women With A Diagnosis Of Obstructive Sleep Apnea (Osa): A Dissertation, Kathleen J. Menard 2015 University of Massachusetts Medical School Worcester

Experience Of Women With A Diagnosis Of Obstructive Sleep Apnea (Osa): A Dissertation, Kathleen J. Menard

Graduate School of Nursing Dissertations

This qualitative descriptive (QD) study examined the experience of the woman newly diagnosed with obstructive sleep apnea (OSA). The study employed Leventhal’s Self- Regulatory Theory to understand women’s illness representation of OSA, cognitive and emotional coping, and situational appraisal skills in coming to terms with OSA. The specific aims were to: 1) Describe the illness representation of women with a recent diagnosis (within one year) of OSA; 2) Describe the cognitive perceptions and emotional response to diagnosis and treatment of OSA in this sample of women; and, 3) Describe the meaning of OSA and the coping strategies used ...


Beyond Anthropomorphism: Attributing Psychological Properties To Animals, Kristin Andrews 2015 York University

Beyond Anthropomorphism: Attributing Psychological Properties To Animals, Kristin Andrews

Kristin Andrews, Ph.D.

In the context of animal cognitive research, “anthropomorphism” is defined as the attribution of uniquely human mental characteristics to non-human animals. Those who worry about anthropomorphism in research are confronted with the question of which properties are uniquely human. As animals, humans and non-human animals1 share a number of biological, morphological, relational, and spatial properties. In addition, it is widely accepted and humans and animals share some psychological properties such as the ability to fear or desire. These claims about the properties animals share with humans are often the products of empirical work.


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