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Using Mathematical Models Of Biological Processes In Genome-Wide Association Studies Of Psychiatric Disorders, Amy Cochran 2017 University of Michigan-Ann Arbor

Using Mathematical Models Of Biological Processes In Genome-Wide Association Studies Of Psychiatric Disorders, Amy Cochran

Biology and Medicine Through Mathematics Conference

No abstract provided.


Computational Modeling Of Contrast Sensitivity And Orientation Tuning In Schizophrenia, Steven M. Silverstein, Docia L. Demmin, James A. Bednar 2017 Rutgers University - New Brunswick/Piscataway

Computational Modeling Of Contrast Sensitivity And Orientation Tuning In Schizophrenia, Steven M. Silverstein, Docia L. Demmin, James A. Bednar

MODVIS Workshop

Computational modeling is being increasingly used to understand schizophrenia, but, to date, it has not been used to account for the common perceptual disturbances in the disorder. We manipulated schizophrenia-relevant parameters in the GCAL (gain control, adaptation, laterally connected) model (Stevens et al., 2013), run using the Topographica simulator (Bednar, 2012), to model low-level visual processing changes in the disorder. Our models incorporated: separate sheets for retinal, LGN, and V1 activity; gain control in the LGN; homeostatic adaptation in V1 based on a weighted sum of all inputs and limited by a logistic (sigmoid) nonlinearity; lateral excitation and inhibition in ...


Education Mitigates The Relationship Of Stress And Mental Disorders Among Rural Indian Women, Nisha Fahey, Apurv Soni, Jeroan J. Allison, Jagdish Vankar, Anusha Prabhakaran, Tiffany A. Moore Simas, Nancy Byatt, Ajay Phatak, Eileen O'Keefe, Somashekhar Nimbalkar 2017 Des Moines University

Education Mitigates The Relationship Of Stress And Mental Disorders Among Rural Indian Women, Nisha Fahey, Apurv Soni, Jeroan J. Allison, Jagdish Vankar, Anusha Prabhakaran, Tiffany A. Moore Simas, Nancy Byatt, Ajay Phatak, Eileen O'Keefe, Somashekhar Nimbalkar

Nancy Byatt

BACKGROUND: Common mental disorders (CMD) are a constellation of mental health conditions that include depression, anxiety, and other related nonpsychotic affective disorders. Qualitative explanatory models of mental health among reproductive-aged women in India reveal that distress is strongly associated with CMD. The relationship of perceived stress and CMD might be attenuated or exacerbated based on an individual's sociodemographic characteristics.

OBJECTIVES: To screen for Common Mental Disorders (CMD) among reproductive-aged women from rural western India and explore how the relationship between perceived stress and CMD screening status varies by sociodemographic characteristics.

METHODS: Cross-sectional survey of 700 women from rural Gujarat ...


An Analysis Of Neurogenesis In A Mouse Model Of Chemotherapy Related Cognitive Impairment, Maxwell A. Hennings 2017 University of Maine

An Analysis Of Neurogenesis In A Mouse Model Of Chemotherapy Related Cognitive Impairment, Maxwell A. Hennings

Electronic Theses and Dissertations

Cancer patients treated with adjuvant chemotherapy often experience cognitive decline following treatment. This phenomenon, often dubbed “chemo brain” or “chemo fog” is usually temporary, but for a subset of survivors, these cognitive impairments can be long-lasting (>10 years) and negatively affect patients’ quality of life, career performance, and social fulfillment. While it is unclear what neurobiological mechanisms underlie chemotherapy related cognitive impairment, the majority of the animal literature has focused on adult neurogenesis. One process important for neurogenesis is the proliferation of new neurons within the dentate gyrus of the hippocampus. It is evident that many chemotherapy agents can negatively ...


Schizophrenia And Its Effects On An American Family: A Call To Action For The 21st Century, Cynthia Newton Captain 2017 Dominican University of California

Schizophrenia And Its Effects On An American Family: A Call To Action For The 21st Century, Cynthia Newton Captain

Senior Theses and Capstone Projects

Our country’s healthcare system is at a moral crossroads. The way we treat those whom we call “the homeless” is deplorable. The majority of the homeless are mentally ill and need treatment. Our country needs to treat those with the severe brain diseases of schizophrenia, schizo-affective disorder, and bi-polar disorder just as we would Alzheimer’s disease and Parkinson’s disease. Those with severe mental illness, who have no insight into their illness, should not be allowed to dictate their own treatment. If a homeless person is brought to San Francisco General Hospital and is found to be a ...


The Experience Of Generalized Anxiety Disorder Through The Lens Of Abraham Lincoln: The Effects Of Mental Health Stigma, Daryl Claude Medina 2017 Dominican University of California

The Experience Of Generalized Anxiety Disorder Through The Lens Of Abraham Lincoln: The Effects Of Mental Health Stigma, Daryl Claude Medina

Senior Theses and Capstone Projects

Living with generalized anxiety disorder, also known as GAD, in the United States of America is difficult not only for the individual, but also for the people around him or her. Lifestyle changes have to be made, family dynamics need to be adjusted, and last but not least, all relationships must become flexible. In fact, these major life changes are never fixed and must continually adapt to the needs of the individual with generalized anxiety disorder since it is a lifelong medical condition. As with any other mental illness, dealing with generalized anxiety disorder takes great sacrifice in terms of ...


Mental Health 101: Teaching Students And Campus Leaders How To Help Those In Crisis, Megan B. Kuhnly 2017 University of Rhode Island

Mental Health 101: Teaching Students And Campus Leaders How To Help Those In Crisis, Megan B. Kuhnly

Senior Honors Projects

One in four Americans ages 18 and older live with a diagnosable mental health disorder. Due to this high prevalence it is very likely that everyone will encounter someone dealing with a mental health crisis in his or her lifetime. Many college students will experience a crisis during their four years of study due to the high levels of stress and psychological triggers. However, we are often not taught how to help these individuals and the resources available are not well advertised. This lack of education and awareness leads to many students being forced to suffer alone and their mental ...


Psycheducational Manual For Families Of People With Schizophrenia, Shiva Fatemifiroozabadi 2017 Dominican University of California

Psycheducational Manual For Families Of People With Schizophrenia, Shiva Fatemifiroozabadi

Scholarly & Creative Works Conference 2017

Although schizophrenia is a relatively rare mental dysfunction, it causes significant discomforts for the patients and their family. As this mental illness usually starts at the young ages and lingers virtually forever, it affects almost every aspect of patients and their family’s life. Schizophrenia deteriorates the individual’s ability to normally interact with others in multiple settings be it family, workplace, and society.

Moreover, the negative and mainly false perceptions towards this illness among the general public intensifies the problems of schizophrenic patients and their families. This prejudice, combined with the inherent problems of the illness, forms a recipe ...


Links Between Physical And Mental Health: Assessment Of Therapeutic Riding’S Effect On Children With Special Needs, Sabah I. Hasan 2017 Brescia University College

Links Between Physical And Mental Health: Assessment Of Therapeutic Riding’S Effect On Children With Special Needs, Sabah I. Hasan

Brescia Psychology Undergraduate Honours Theses

This observational study examined the effect of therapeutic riding (TR) on four domains, physical skills, positive values, social skills, and self-identity in children with special needs. Participants were recruited from SARI Therapeutic Riding and were divided, based on observation, into more or less severe diagnosis categories. It was predicted that children with less severe diagnosis would show more of an increase on the four domains, especially physical skills due to TR. Participants were observed using an observational checklist at pre- and post-riding lessons. Results showed non-significant differences in all four domains, however, there was a tendency for scores to increase ...


Personality Disorders And Epigenetics, Julie Zaccagnino 2017 Germanna Community College

Personality Disorders And Epigenetics, Julie Zaccagnino

Student Writing

Personality Disorders are characterized by chronic and pervasive maladaptive patterns which cause emotional distress to the individual, his/her relationships, and society. The purpose of analysis is to understand the causes of personality disorders. Genetic influence on personality is not a simple cause-and-effect. Several genes have been identified to be associated with personality traits but not cause personality traits. Personality disorders have been also associated with childhood trauma. Evidence in research has shown that childhood maltreatment is marked by DNA methylation of genes which promote glucocorticoid receptors in the synapses of the hippocampus and as well as serotonergic pathways. The ...


Journal Of Mind And Medical Sciences: Translational And Integrative Mission, David L. Rowland, Ion G. Motofei 2017 Valparaiso University

Journal Of Mind And Medical Sciences: Translational And Integrative Mission, David L. Rowland, Ion G. Motofei

Journal of Mind and Medical Sciences

Initiated four years ago, Journal of Mind and Medical Sciences (J Mind Med Sci.) established the mission to publish papers on mental and medical topics in distinct but closely interrelated domains. The editorial policy especially encourages interdisciplinary and integrative perspectives, being equally focused on basic research and clinical investigations and short reports.

The journal adheres to the philosophy that high quality, original ideas and information should be readily accessible and freely shared within and amongst the scientific community. Accordingly, J Mind Med Sci. is an online, open access, non-for-profit journal which, because of individual/ private support, has levied no charges ...


Mental Disorder And Criminal Justice, Stephen J. Morse 2017 University of Pennsylvania Law School

Mental Disorder And Criminal Justice, Stephen J. Morse

Faculty Scholarship

This paper is a chapter that will appear in ACADEMY FOR JUSTICE, A REPORT ON SCHOLARSHIP AND CRIMINAL JUSTICE REFORM (Erik Luna ed., forthcoming 2017). The criminal law treats some people with severe mental disorders doctrinally and practically differently at virtually every stage of the criminal justice process, beginning with potential incompetence to stand trial and ending with the question of competence to be executed, and such people have special needs when they are in the system. This chapter begins by exploring the fundamental mental health information necessary to make informed judgements about how the criminal justice system should respond ...


Diet And Cognition: Data, Theory, And Some Solutions From The Playbook Of Psychology, Aaron P. Blaisdell 2017 University of California, Los Angeles

Diet And Cognition: Data, Theory, And Some Solutions From The Playbook Of Psychology, Aaron P. Blaisdell

Journal of Evolution and Health

No abstract provided.


Eating Disorders: Identifying, Assessing, And Treatment, Valerie M. Miranda 2017 Eating Disorders Recovery Center of Athens

Eating Disorders: Identifying, Assessing, And Treatment, Valerie M. Miranda

National Youth-At-Risk Conference Savannah

This presentation will address DSM-V criteria for feeding and eating disorders, demographics for eating disorders, long-term medical issues associated with eating disorders, assessment measures for feeding and eating disorders, and resources for the community. Being able to identify, assess, and treat eating disorders within the children and adolescent population is crucial in their long-term physical development and mental health as eating disorders typically begin in mid-adolescence.


Understanding Increasing College Anxiety: The Need For Anxiety Awareness Campaigns, Taylor Mosher 2017 California Polytechnic State University, San Luis Obispo

Understanding Increasing College Anxiety: The Need For Anxiety Awareness Campaigns, Taylor Mosher

Journalism

The following study investigates national trends toward increasing anxiety among the college student demographic with particular attention paid to the ways in which public awareness campaigns may be implemented as a method for reducing stigma, increasing awareness of anxiety conditions, and connecting students to critical resources.

In order to improve understanding surrounding student anxiety, the following research was conducted in two parts. First, secondary national research was conducted analyzing relevant literature surrounding anxiety trends among college students, the response of universities across the nation, and potential methods by which to relieve student anxiety. Following the conclusion of this research, primary ...


Rumination Is Associated With Diminished Performance Monitoring, Ema Tanovic, Greg Hajack, Charles A. Sanislow 2017 Yale University

Rumination Is Associated With Diminished Performance Monitoring, Ema Tanovic, Greg Hajack, Charles A. Sanislow

Charles A. Sanislow

Rumination is a construct that cuts across a variety of disorders, including anxiety and depression. It has been associated with deficits in cognitive control thought to confer risk for psychopathology. One aspect of cognitive control that is especially relevant to the content of ruminative thoughts is error processing. We examined the relation of rumination and 2 electrophysiological indices of error processing, error related negativity (ERN), an early index of error detection, and error positivity (Pe), a later index of error awareness. Consistent with prior work, ERN was negatively correlated with anxiety (i.e., more anxious individuals were characterized by larger ...


Involuntary Competence In United States Criminal Law, Stephen J. Morse 2017 University of Pennsylvania Law School

Involuntary Competence In United States Criminal Law, Stephen J. Morse

Faculty Scholarship

This is a draft of a chapter that has been accepted for publication by Oxford University Press in the forthcoming book Fitness to Plead: International and Comparative Perspectives edited by Ronnie Mackay and Warren Brookbanks due for publication in May 2018. It addresses whether the state may forcibly medicate an unwilling defendant or prisoner to restore competence in the criminal process, including competence to stand trial, competence to plead guilty and to waive trial rights, competence to represent oneself, and competence to be sentenced. It begins with a description of the doctrinal and mental health background information and the right ...


Dysfunctional Error-Related Processing In Incarcerated Youth With Elevated Psychopathic Traits, J. Michael Maurer, Vaughn R. Steele, Lora M. Cope, Gina M. Vincent, Julia M. Stephen, Vince D. Calhoun, Kent A. Kiehl 2017 University of New Mexico

Dysfunctional Error-Related Processing In Incarcerated Youth With Elevated Psychopathic Traits, J. Michael Maurer, Vaughn R. Steele, Lora M. Cope, Gina M. Vincent, Julia M. Stephen, Vince D. Calhoun, Kent A. Kiehl

Gina M. Vincent

Adult psychopathic offenders show an increased propensity towards violence, impulsivity, and recidivism. A subsample of youth with elevated psychopathic traits represent a particularly severe subgroup characterized by extreme behavioral problems and comparable neurocognitive deficits as their adult counterparts, including perseveration deficits. Here, we investigate response-locked event-related potential (ERP) components (the error-related negativity [ERN/Ne] related to early error-monitoring processing and the error-related positivity [Pe] involved in later error-related processing) in a sample of incarcerated juvenile male offenders (n=100) who performed a response inhibition Go/NoGo task. Psychopathic traits were assessed using the Hare Psychopathy Checklist: Youth Version (PCL:YV ...


Diagnostic Performance And Optimal Cut-Off Scores Of The Massachusetts Youth Screening Instrument-Second Version In A Sample Of Swiss Youths In Welfare And Juvenile Justice Institutions, Claudia Dolitzsch, Laura E. W. Leenarts, Klaus Schmeck, Jorg M. Fegert, Thomas Grisso, Marc Schmid 2017 Universitätsklinikum

Diagnostic Performance And Optimal Cut-Off Scores Of The Massachusetts Youth Screening Instrument-Second Version In A Sample Of Swiss Youths In Welfare And Juvenile Justice Institutions, Claudia Dolitzsch, Laura E. W. Leenarts, Klaus Schmeck, Jorg M. Fegert, Thomas Grisso, Marc Schmid

Psychiatry Publications and Presentations

BACKGROUND: There is a growing consensus about the importance of mental health screening of youths in welfare and juvenile justice institutions. The Massachusetts Youth Screening Instrument-second version (MAYSI-2) was specifically designed, normed and validated to assist juvenile justice facilities in the United States of America (USA), in identifying youths with potential emotional or behavioral problems. However, it is not known if the USA norm-based cut-off scores can be used in Switzerland. Therefore, the primary purpose of the current study was to estimate the diagnostic performance and optimal cut-off scores of the MAYSI-2 in a sample of Swiss youths in welfare ...


A Study Of Media Portrayal Of Schizophrenics To Understand How Stigma Associated With Schizophrenia May Be Reversed, Rainielle M. Cua 2017 Virginia Commonwealth University

A Study Of Media Portrayal Of Schizophrenics To Understand How Stigma Associated With Schizophrenia May Be Reversed, Rainielle M. Cua

Undergraduate Research Posters

The news media are one of the most influential sources of information regarding mental illness. Media coverage on schizophrenia, one of the most stigmatized mental illnesses, tends to be negative, focusing on high risks of violence, failure, and unpredictability. Such perceptions may cause a detrimental impact on the mentally ill and cause them to internalize a stigmatizing stereotype and hinder the public’s understanding of mental illness. I studied how media portrayal in newspaper coverage of schizophrenics has evolved to discover how nonfiction media representation has affected people’s perceptions and attitudes towards schizophrenics and to propose an implementable solution ...


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