Computational Pharmacology: Simulating Circuits Of The Brain For Drug Development, 2010 Portland State University
Computational Pharmacology: Simulating Circuits Of The Brain For Drug Development, Patrick D. Roberts
Systems Science Friday Noon Seminar Series
The pharmaceutical industry is approaching unsustainable research costs to develop new drug therapies for mental disease because of the high failure rate in clinical trials. These failures are due to limitations of pre-clinical studies in animal models that fail to predict the efficacy of new drugs in human subjects. The gap between pre-clinical trials and clinical trials is particularly difficult in complex mental diseases such as schizophrenia because of the complex dynamics of the brain and the multiple chemical pathways that drugs can affect.
However, many biological mechanisms associated with schizophrenia are now understood, and computational power and methods have ...
Predictors Of Depressive Symptomatology In Family Caregivers Of Wom-En With Substance Use Disorders Or Co-Occurring Substance Use And Mental Disorders, 2010 Mandel School of Applied Social Sciences, Case Western Reserve University
Predictors Of Depressive Symptomatology In Family Caregivers Of Wom-En With Substance Use Disorders Or Co-Occurring Substance Use And Mental Disorders, David E. Biegel, Shari Katz-Saltzman, David Meeks, Suzanne Brown, Elizabeth M. Tracy
Social Work Faculty Publications
This study utilized a stress-process model to examine the impact of having a female family member with substance use or co-occurring substance use and mental disorders on family caregivers' depressive symptomatology. Participants were 82 women receiving substance abuse treatment and the family member providing the most social support for each woman. Greater caregiver depressive symptomatology was predicted by greater care recipient emotional problems, less care recipient social support, and poor caregiver health. Implications of findings for treatment and future research are discussed
Exploring The Impact Of Race On Mental Health Service Utilization Among African Americans And Whites With Severe Mental Illness, 2010 Samuel Merritt University
Exploring The Impact Of Race On Mental Health Service Utilization Among African Americans And Whites With Severe Mental Illness, Michelle Hampton, Linda Chafetz, Mary White
BACKGROUND: Disparities among African Americans and Whites with severe mental illness have been identified in numerous studies. Yet it remains unknown if disparities are associated with race or other vulnerabilities common to this population. OBJECTIVES: This study used the Behavioral Model for Vulnerable Populations to examine mental health service utilization among 155 African Americans and Whites with severe mental illness for 12 months after discharge from a residential crisis program. DESIGN: This cross-sectional study was a secondary analysis of data from a randomized trial. RESULTS: Race did not emerge as a significant predictor of mental health service utilization. Factors associated ...
The Medicalization Of Hyperactivity And Inattentiveness : A Social History And Theoretical Perspectives On Adhd, Justin Douglas Brock
Theses, Dissertations and Capstones
This study investigates the rise of the Attention-Deficit/Hyperactivity Disorder diagnosis. It approaches the topic from a medicalization perspective and frames it under the therapeutic state as proposed by Nicholas Kittrie in 1971. It asks three questions: how has society, and particularly, the medical community changed to allow the medicalization of hyperactivity and social control of active children? How has the continuing diagnosis of hyperactivity in children expanded to include attention deficit hyperactivity disorder in both children and adults? And what forces are behind the continuously inclusive diagnosis and why? In an attempt to answer these questions the history of ...
A Vignette Study Examining The Accuracy Of Diagnosis: The Role Of Patient And Practitioner Gender And Race Match, 2010 Wayne State University
A Vignette Study Examining The Accuracy Of Diagnosis: The Role Of Patient And Practitioner Gender And Race Match, Kevin Johnson
Wayne State University Dissertations
DIAGNOSING MENTAL ILLNESS
Advisor: Dr. Janet R. Hankin
Major: Medical Sociology
Degree: Doctor of Philosophy in Sociology
A convenience snowball sample of 228 mental health practitioners were surveyed and administered two vignettes of persons with mental illness and a 12-question survey that included occupational background and attitudinal questions about diagnosing mental illness. The gender and race of the patients were randomly altered, while the symptoms and characteristics of mental illness remained constant for each vignette. Each practitioner assigned a DSM-IV diagnostic label for axis I and axis II on both vignettes. The surveys were coded ...
Internalized Stigma As A Barrier To Improvement In Vocational Functioning Among People With Schizophrenia-Spectrum Disorders, Philip T. Yanos, Paul Lysaker, David Roe
Publications and Research
We examined the relationship between internalized stigma and changes in vocational function. Persons with schizophrenia or schizoaffective disorder (n=78) were assessed at baseline and 5 months after vocational rehabilitation. Internalized stigma and cognitive–behavioral treatment predicted change in vocational functioning, supporting the view that internalized stigma compromises vocational outcomes.
Post-Traumatic Stress Disorder: Guiding Management With Careful Assessment Of Comorbid Mental And Physical Illness, Don Richardson, Diane Mcintosh, Murray B. .Stein, Jitender Sareen
MacDonald Franklin OSI Research Centre
Post-traumatic stress disorder (PTSD) is a common and serious psychiatric condition in the civilian and veteran population. The lifetime prevalence of PTSD in the Canadian general population is 9.2%, which, surprisingly, is not significantly different from the 7.2% lifetime prevalence rate within the Canadian Regular Forces. In Canadian veterans pensioned with a medical condition the 1-month prevalence was 10.3%. Given the serious functional impairment and impaired quality of life associated with PTSD, careful assessment and treatment of PTSD is warranted. Due to the complex clinical presentation of PTSD, which can include symptoms across the continuum from adjustment ...
Denominational Support For Clergy Mental Health, 2010 George Fox University
Denominational Support For Clergy Mental Health, Bobby L. Trihub, Mark R. Mcminn, William C. Buhrow, Thomas F. Johnson
Faculty Publications - Grad School of Clinical Psychology
To date, minimal research has addressed the actual services provided to maintain the mental health of leadership in the church. Three major Protestant denominations were consulted within this study, including a total of 434 pastors across the United States. Among these three denominations, a range of services are now being offered to support clergy, with services such as time off, prayer support groups, and clergy retreats among the most valued, adequately provided, and utilized. Still, clergy do not see the provision of services as fully adequate, and report a number of obstacles to utilizing services. Generally, the most highly rated ...
The Latina/O Mental Health Paradox Or Racial/Ethnic Disparities? Depression Among New Immigrants To The U.S, 2010 University of Texas at El Paso
The Latina/O Mental Health Paradox Or Racial/Ethnic Disparities? Depression Among New Immigrants To The U.S, Sandra Iveth Ramirez
Open Access Theses & Dissertations
The Latino/a Mental Health Paradox states that the foreign-born immigrants have better mental health outcomes when compared with native-born groups of various ethno-racial backgrounds, with the gap in mental stress minimizing overtime. The objective of this study is to examine whether Latina/os immigrants suffer an ethno-racial disparity in mental health or if they have favorable mental health outcomes as predicted by the Paradox. Expanding on the Latina/o Mental Health Paradox, rather than comparing Latina/o immigrants with native-born, this study will compare depression among recently legalized Latina/os with recent legalized European immigrants.
Personality Disorders And Moral Responsibility, 2010 Chapman University
Personality Disorders And Moral Responsibility, Mike W. Martin
Philosophy Faculty Articles and Research
In “Personality Disorders: Moral or Medical Kinds—or Both?” Peter Zachar and Nancy Nyquist Potter (2010) reject any general dichotomy between morality and mental health, and specifically between character vices and personality disorders. In doing so, they provide a nuanced and illuminating discussion that connects Aristotelian virtue ethics to a multidimensional understanding of personality disorders. I share their conviction that dissolving morality–health dichotomies is the starting point for any plausible understanding of human beings (Martin 2006), but I register some qualms about their discussion of responsibility.
The Impact Of A Mental Health-Related Diagnosis On Readmission Rates For Heart Failure, 2010 Lehigh Valley Health Network
The Impact Of A Mental Health-Related Diagnosis On Readmission Rates For Heart Failure, Ronald S. Freudenberger Md, Carol A. Foltz Phd, Lou A. Lukas Md, Donna F. Petruccelli Crnp, Hannah D. Paxton Rn, Mph, Victoria Sabella Bsn
Department of Medicine
No abstract provided.
Early Psychosis Intervention In Oregon: Building A Positive Future For This Generation, 2010 Portland State University
Early Psychosis Intervention In Oregon: Building A Positive Future For This Generation, Ryan P. Melton, Tamara Sale
Regional Research Institute
The article focuses on the importance of early Schizophrenia intervention.
Comprehensive Evidence-Based Program Teaching Self-Management Of Auditory Hallucinations On Inpatient Psychiatric Units, 2010 University of San Francisco
Comprehensive Evidence-Based Program Teaching Self-Management Of Auditory Hallucinations On Inpatient Psychiatric Units, Robin Buccheri, L Trygstad, M Buffum, K Lyttle, G Dowling
Nursing and Health Professions Faculty Research and Publications
Patients hearing command hallucinations to harm whose only self-management strategies are to obey these commands, can represent serious safety concerns on inpatient psychiatric units. A comprehensive evidence-based program teaching self-management of auditory hallucinations on inpatient psychiatric units is described that includes five components: suggestions for staff education; patient self-assessment tools; an interview guide and safety protocol; a course to teach strategies for managing distressing voices and commands to harm; suggestions to improve staff communication; and a plan to extend the program from inpatient care settings into the community by sharing materials with community case managers and caregivers when patients are ...
Prenatal Beta-Endorphin As An Early Predictor Of Postpartum Depressive Symptoms In Euthymic Women, 2010 University of California - Irvine
Prenatal Beta-Endorphin As An Early Predictor Of Postpartum Depressive Symptoms In Euthymic Women, Ilona S. Yim, Laura M. Glynn, Christine Dunkel Schetter, Calvin J. Hobel, Aleksandra Chicz-Demet, Curt A. Sandman
Psychology Faculty Articles and Research
After delivery, many women experience symptoms of postpartum depression (PPD), and early identification of women at risk is therefore important. The opioid peptide [beta]-endorphin has been implicated in non-puerperal depression but its role in the development of PPD is unknown.
Mission Diversion & Recovery For Traumatized Veterans (Mission Direct Vet): Early Findings And Lessons Learned, 2010 University of Massachusetts Medical School
Mission Diversion & Recovery For Traumatized Veterans (Mission Direct Vet): Early Findings And Lessons Learned, Paul P. Christopher, Elizabeth A. Aaker, Amanda Lennox, William H. Fisher, Carl E. Fulwiler, Stephanie W. Hartwell, David Smelson, Debra A. Pinals
Implementation Science and Practice Advances Research Center Publications
MISSION DIRECT VET is a SAMHSA- funded, court based diversion program targeting veterans in Massachusetts with trauma-related mental health and substance use problems. MISSION-DIRECT VET seeks to: Reduce criminal justice involvement Treat mental health, substance abuse and other trauma related symptoms Use a systematic wrap-around model Provide care coordination, peer support and trauma informed services Develop interagency partnerships to serve veterans with co-occurring disorders
Introversion And Autism: A Conceptual Exploration Of The Placement Of Introversion On The Autism Spectrum, 2010 University of Central Florida
Introversion And Autism: A Conceptual Exploration Of The Placement Of Introversion On The Autism Spectrum, Jennifer Grimes
Electronic Theses and Dissertations, 2004-2019
The conceptualization of the personality construct of introversion has been problematic since the term's inception due to the complexity and seemingly self-contradictory nature of the collection of attributes of which it is comprised. To advance the understanding of introversion, I propose that it is a continuous segment of the non-clinical part of the autism spectrum, and that it is not the same as the inverse of extraversion. When introversion and autism are placed on the same continuum, the nature of the relationship of the traits becomes more apparent, and new possibilities are available for exploration of both autism and ...
Expanding The Sea Program: Course Conception, Rationale And A Plan For Implementation, 2010 Minnesota State University - Mankato
Expanding The Sea Program: Course Conception, Rationale And A Plan For Implementation, Michelle Schulz
All Theses, Dissertations, and Other Capstone Projects
The Student Educational Adventures (SEA) Program was created in 1995 to help motivate youth with Emotional/Behavioral Disorders (E/BD) to view education as important as well as to assist with the graduation rate of students with E/BD. Using an experiential method of teaching, each of the four courses in the SEA Program are specifically designed to teach life-long skills, such as team building, decision making, service, leadership, conflict resolution, anger management, goal setting, and taking responsibility, to youth who typically struggle in those areas.
Due to the current financial state of SEA Program funders, the Goodhue County Education ...
Building Global Citizenship Through Network Leadership, 2010 National Survivor User Network
Building Global Citizenship Through Network Leadership, Anne Beales, Daniel B. Fisher
Implementation Science and Practice Advances Research Center Publications
This article is based upon a paper delivered by Anne Beales about the Interrelate group to the International Initiative for Mental Health Leadership, IIMHL, Conference in Killarney, Ireland, May 2010, and developed by the Interrelate group: Daniel Fisher, US, Shaun McNeil, Scotland, Jenny Speed, Australia, Paddy MacGowan, Ireland, Gary Platz, New Zealand, and Joan Edwards-Karmazyn, Canada.
The Learning And Working During The Transition To Adulthood Rehabilitation Research And Training Center, 2010 University of Massachusetts Medical School
The Learning And Working During The Transition To Adulthood Rehabilitation Research And Training Center, Maryann Davis, Jonathan Delman, Marsha Langer Ellison, Charles W. Lidz
Implementation Science and Practice Advances Research Center Publications
Research and dissemination activities are singularly focused on developing knowledge for and about developmentally appropriate services that help transition Age Youth and Young Adults (TAYYA) with Serious Mental Health Conditions (SMHC) successfully complete their schooling and training and launch their adult working careers.
The Mediating Role Of Psychological Distress In The Relationship Between Adverse Childhood Experiences And Adult Smoking, Tara Wynn Strine
Walden Dissertations and Doctoral Studies
While research has indicated that impaired mental health partially mediates the relationship between adverse childhood experiences (ACEs) and alcohol and illicit drug use, little research has examined potential mediators in the relationship between ACEs and smoking, the number one cause of preventable mortality in the United States. Accordingly, this study examined the potential mediating effect of psychological distress on the relationship between ACES and smoking using data from Wave II of the ACE Study, a cross-sectional study completed between June and October of 1997 on a sample of adult health maintenance organization members (N = 7,211). The theoretical underpinnings for ...