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Full-Text Articles in Education

Cardiac, Skeletal, And Smooth Muscle Mitochondrial Respiration: Are All Mitochondria Created Equal?, Song-Young Park, J. R. Gifford, R. H. I. Andtbacka, Joel D. Trinity, John R. Hyngstrom, Ryan S. Garten, Nikolaos A. Diakos, S. J. Ives, Flemming Dela, Steen Larsen, Stavros Drakos, Russell S. Richardson Aug 2014

Cardiac, Skeletal, And Smooth Muscle Mitochondrial Respiration: Are All Mitochondria Created Equal?, Song-Young Park, J. R. Gifford, R. H. I. Andtbacka, Joel D. Trinity, John R. Hyngstrom, Ryan S. Garten, Nikolaos A. Diakos, S. J. Ives, Flemming Dela, Steen Larsen, Stavros Drakos, Russell S. Richardson

Health and Kinesiology Faculty Publications

Unlike cardiac and skeletal muscle, little is known about vascular smooth muscle mitochondrial respiration. Therefore, the present study examined mitochondrial respiratory rates in smooth muscle of healthy human feed arteries and compared with that of healthy cardiac and skeletal muscles. Cardiac, skeletal, and smooth muscles were harvested from a total of 22 subjects (53 ± 6 yr), and mitochondrial respiration was assessed in permeabilized fibers. Complex I + II, state 3 respiration, an index of oxidative phosphorylation capacity, fell progressively from cardiac to skeletal to smooth muscles (54 ± 1, 39 ± 4, and 15 ± 1 pmol·s−1·mg−1, P < 0.05, respectively). Citrate synthase (CS) activity, an index of mitochondrial density, also fell progressively from cardiac to skeletal to smooth muscles (222 ± 13, 115 ± 2, and 48 ± 2 μmol·g−1·min−1, P …


Effects On Oxygen Consumption And Metabolic Gene Expression When Determining Experimental Exercise Intensity Based On Exercise Capacity Tests Conducted In Hypoxic And Normoxic Environments, Dustin Slivka, Matthew Ws Heesch, Charles L. Dumke, John S. Cuddy, Walter S. Hailes, Brent C. Ruby Jan 2014

Effects On Oxygen Consumption And Metabolic Gene Expression When Determining Experimental Exercise Intensity Based On Exercise Capacity Tests Conducted In Hypoxic And Normoxic Environments, Dustin Slivka, Matthew Ws Heesch, Charles L. Dumke, John S. Cuddy, Walter S. Hailes, Brent C. Ruby

Health and Kinesiology Faculty Publications

Abstract: Exercise intensity can be set relative to VO2 max measured during hypoxic or control conditions in studies investigating exercise in hypoxic environments. It currently is not clear which is the most appropriate method.

Objective: The objective of this brief report is to determine the response to 1 hour of cycling at 60% of peak power when measured in either normoxic or hypoxic conditions.

Methods: Eleven recreationally active male participants (24 ± 4 yrs, 173 ± 20 cm, 82 ± 12 kg, 15.2 ± 7.1% fat, 4.0 ± 0.6 L x min-1 VO2 max) completed two 1 …


A Qualitative Study Exploring Women’S Beliefs About Physical Activity After Stillbirth, Jennifer Huberty, Jason Coleman, Katherine Rolfsmeyer, Serena Wu Jan 2014

A Qualitative Study Exploring Women’S Beliefs About Physical Activity After Stillbirth, Jennifer Huberty, Jason Coleman, Katherine Rolfsmeyer, Serena Wu

Health and Kinesiology Faculty Publications

Background: Research provides strong evidence for improvements in depressive symptoms as a result of physical activity participation in many populations including pregnant and post-partum women. Little is known about how women who have experienced stillbirth (defined as fetal death at 20 or more weeks of gestation) feel about physical activity or use physical activity following this experience. The purpose of this study was to qualitatively explore women’s beliefs about physical activity following a stillbirth.

Methods: This was an exploratory qualitative research study. Participants were English-speaking women between the ages of 19 and 44 years who experienced a stillbirth …


Α1-Adrenergic Responsiveness In Human Skeletal Muscle Feed Arteries: The Impact Of Reducing Extracellular Ph, S. J. Ives, R. H. I. Andtbacka, R. D. Noyes, R. Garrett Morgan, J. R. Gifford, Song-Young Park, J. David Symons, Russell S. Richardson Jul 2012

Α1-Adrenergic Responsiveness In Human Skeletal Muscle Feed Arteries: The Impact Of Reducing Extracellular Ph, S. J. Ives, R. H. I. Andtbacka, R. D. Noyes, R. Garrett Morgan, J. R. Gifford, Song-Young Park, J. David Symons, Russell S. Richardson

Health and Kinesiology Faculty Publications

  • What is the central question of this study?

    In human arteries involved in the regulation of muscle blood flow, there is a lack of data about whether acidosis alters vascular sensitivity to vasoactive agents, as well as altering endothelium dependent vasorelaxation. Little is known about the interaction of metabolites and vascular function in human skeletal muscle feed arteries.

  • What is the main finding and its importance?

    Increasing acidosis attenuated the response and sensitivity of the arteries to phenylephrine; this effect was selective to the receptor over smooth muscle.

    Acidosis did not alter endothelium dependent vasorelaxation. Impaired vasoconstriction coupled with …


Yoga Training Improves Metabolic Parameters In Obese Boys, Dae Yun Seo, Sungryul Lee, Arturo Figueroa, Hyoung Kyu Kim, Yeong Ho Baek, Yi Sub Kwak, Nari Kim, Tae Hoon Choi, Byoung Doo Rhee, Kyung-Soo Kim, Byung Joo Park, Song-Young Park, Jin Han Jun 2012

Yoga Training Improves Metabolic Parameters In Obese Boys, Dae Yun Seo, Sungryul Lee, Arturo Figueroa, Hyoung Kyu Kim, Yeong Ho Baek, Yi Sub Kwak, Nari Kim, Tae Hoon Choi, Byoung Doo Rhee, Kyung-Soo Kim, Byung Joo Park, Song-Young Park, Jin Han

Health and Kinesiology Faculty Publications

Yoga has been known to have stimulatory or inhibitory effects on the metabolic parameters and to be uncomplicated therapy for obesity. The purpose of the present study was to test the effect of an 8-week of yoga-asana training on body composition, lipid profile, and insulin resistance (IR) in obese adolescent boys. Twenty volunteers with body mass index (BMI) greater than the 95th percentile were randomly assigned to yoga (age 14.7±0.5 years, n=10) and control groups (age 14.6±1.0 years, n=10). The yoga group performed exercises three times per week at 40~60% of heart-rate reserve (HRR) for 8 weeks. IR was determined …


Human Skeletal Muscle Feed Arteries: Evidence Of Regulatory Potential, S. J. Ives, R. H. I. Andtbacka, Song-Young Park, A. J. Donato, J. R. Gifford, R. D. Noyes, L. A. Lesniewski, R. S. Richardson Jun 2012

Human Skeletal Muscle Feed Arteries: Evidence Of Regulatory Potential, S. J. Ives, R. H. I. Andtbacka, Song-Young Park, A. J. Donato, J. R. Gifford, R. D. Noyes, L. A. Lesniewski, R. S. Richardson

Health and Kinesiology Faculty Publications

Aim

Recently, it has been recognized that human skeletal muscle feed arteries can be harvested during exploratory surgery for melanoma. This approach provides vessels for in vitro study from a wide spectrum of relatively healthy humans. Although, the regulatory role of skeletal muscle feed arteries in rodent models has been documented, whether such vessels in humans possess this functionality is unknown.

Methods

Therefore, skeletal muscle feed arteries (~950 μm OD) from 10 humans (48 ± 4, 27–64 years) were studied using pressure myography. Vessel function was assessed using potassium chloride (KCl), phenylephrine (PE), acetylcholine (ACh) and sodium nitroprusside (SNP) concentration–response …


Whole-Body Vibration Training Reduces Arterial Stiffness, Blood Pressure And Sympathovagal Balance In Young Overweight/Obese Women, Arturo Figueroa, Ryan Gil, Alexei Wong, Shirin Hooshmand, Song-Young Park, Florence Vicil, Marcos A. Sanchez-Gonzalez Feb 2012

Whole-Body Vibration Training Reduces Arterial Stiffness, Blood Pressure And Sympathovagal Balance In Young Overweight/Obese Women, Arturo Figueroa, Ryan Gil, Alexei Wong, Shirin Hooshmand, Song-Young Park, Florence Vicil, Marcos A. Sanchez-Gonzalez

Health and Kinesiology Faculty Publications

Obesity is associated with early cardiovascular dysfunction and reduced muscle strength. Whole-body vibration (WBV) training may improve arterial function and muscle strength. The effects of WBV training on arterial stiffness (brachial-ankle pulse wave velocity, baPWV), wave reflection (augmentation index, AIx), brachial systolic blood pressure (bSBP), aortic systolic blood pressure (aSBP), heart rate variability, and muscle strength (one-repetition maximum, 1RM) were examined in 10 young (21±2 year) overweight/obese women (body mass index, BMI=29.9±0.8 kg m–2). Participants were randomized to a 6-week WBV training or non-exercising control (CON) period in a crossover design. WBV training (3 days × week) consisted of static …


Passive Vibration On The Legs Reduces Peripheral And Systemic Arterial Stiffness, Alexei Wong, Marcos A. Sanchez-Gonzalez, Ryan Gil, Florence Vicil, Song-Young Park, Arturo Figueroa Oct 2011

Passive Vibration On The Legs Reduces Peripheral And Systemic Arterial Stiffness, Alexei Wong, Marcos A. Sanchez-Gonzalez, Ryan Gil, Florence Vicil, Song-Young Park, Arturo Figueroa

Health and Kinesiology Faculty Publications

Intermittent leg exercise (10 × 1-min sets) with whole-body vibration (WBV) decreases brachial-ankle pulse-wave velocity (baPWV)1 and leg PWV (legPWV) but not aortic PWV.2 As baPWV is an index of systemic arterial stiffness3 mainly influenced by aortic PWV (∼58%) and legPWV (∼23%),4 previously published results1, 2 suggest that WBV affects baPWV through peripheral but not central PWV. The post-exercise decrease in PWV is associated with vasodilation in the exercised limb.5, 6 Similarly, intermittent WBV (3 × 3-min sets)7 or passive vibration (PV)8 has been shown to increase blood flow in …


Impact Of Passive Vibration On Pressure Pulse Wave Characteristics, M A. Sanchez-Gonzalez, A Wong, F Vicil, R Gil, Song-Young Park, A Figueroa Jun 2011

Impact Of Passive Vibration On Pressure Pulse Wave Characteristics, M A. Sanchez-Gonzalez, A Wong, F Vicil, R Gil, Song-Young Park, A Figueroa

Health and Kinesiology Faculty Publications

The augmentation index (AIx), a marker of wave reflection, decreases following acute leg exercise. Passive vibration (PV) causes local vasodilation that may reduce AIx. This study investigated the effects of acute PV on wave reflection and aortic hemodynamics. In a crossover fashion 20 (M=9, F=11) healthy young (22±3 year) participants were randomized to 10 min PV or no vibration control (CON) trials. Subjects rested in the supine position with their legs over a vibration platform for the entire session. Radial waveforms were obtained by applanation tonometry before and after 3 min (Post-3) and 30 min (Post-30) of PV (∼5.37 G) …