Quantitative Interpretation Of A Genetic Model Of Carcinogenesis Using Computer Simulations,
2011
Wright State University - Main Campus
Quantitative Interpretation Of A Genetic Model Of Carcinogenesis Using Computer Simulations, Donghai Dai, Brandon Beck, Xiaofang Wang, Cory Howk, Yi Li
Mathematics and Statistics Faculty Publications
The genetic model of tumorigenesis by Vogelstein et al. (V theory) and the molecular definition of cancer hallmarks by Hanahan and Weinberg (W theory) represent two of the most comprehensive and systemic understandings of cancer. Here, we develop a mathematical model that quantitatively interprets these seminal cancer theories, starting from a set of equations describing the short life cycle of an individual cell in uterine epithelium during tissue regeneration. The process of malignant transformation of an individual cell is followed and the tissue (or tumor) is described as a composite of individual cells in order to quantitatively account for intra-tumor …
A Primer On Chaos And Fractals,
2011
Western Kentucky University
A Primer On Chaos And Fractals, Bruce Kessler
Mathematics Faculty Publications
This is a prelude to a performance of the play "Arcadia" exclusively for the science and math majors of Lipscomb University. One of the main characters of the story is a mathematical genius, and has realized the power and limitations of iterations in generating mathematical models and structures, although she is living in the early 1800's. This talk gives an introduction to the ideas of chaos theory, fractals, and randomness.
Maximal Sensitive Dependence And The Optimal Path To Epidemic Extinction,
2011
Montclair State University
Maximal Sensitive Dependence And The Optimal Path To Epidemic Extinction, Eric Forgoston, Simone Bianco, Leah B. Shaw, Ira B. Schwartz
Department of Applied Mathematics and Statistics Faculty Scholarship and Creative Works
Extinction of an epidemic or a species is a rare event that occurs due to a large, rare stochastic fluctuation. Although the extinction process is dynamically unstable, it follows an optimal path that maximizes the probability of extinction. We show that the optimal path is also directly related to the finite-time Lyapunov exponents of the underlying dynamical system in that the optimal path displays maximum sensitivity to initial conditions. We consider several stochastic epidemic models, and examine the extinction process in a dynamical systems framework. Using the dynamics of the finite-time Lyapunov exponents as a constructive tool, we demonstrate that …
Complete Characterizations Of Local Weak Sharp Minima With Applications To Semi-Infinite Optimization And Complementarity,
2011
Wayne State University
Complete Characterizations Of Local Weak Sharp Minima With Applications To Semi-Infinite Optimization And Complementarity, Boris S. Mordukhovich, Naihua Xiu, Jinchuan Zhou
Mathematics Research Reports
In this paper we identify a favorable class of nonsmooth functions for which local weak sharp minima can be completely characterized in terms of normal cones and subdifferentials, or tangent cones and subderivatives, or their mixture in finite-dimensional spaces. The results obtained not only significantly extend previous ones in the literature, but also allow us to provide new types of criteria for local weak sharpness. Applications of the developed theory are given to semi-infinite programming and to semi-infinite complementarity problems.
Global Well-Posedness And Asymptotic Behavior Of A Class Of Initial-Boundary-Value Problems Of The Kdv Equation On A Finite Domain,
2011
University of Cincinnati - Main Campus
Global Well-Posedness And Asymptotic Behavior Of A Class Of Initial-Boundary-Value Problems Of The Kdv Equation On A Finite Domain, Ivonne Rivas, Muhammad Usman, Bingyu Zhang
Mathematics Faculty Publications
In this paper, we study a class of initial boundary value problem (IBVP) of the Korteweg- de Vries equation posed on a ?nite interval with nonhomogeneous boundary conditions. The IBVP is known to be locally well-posed, but its global L2 a priori estimate is not available and therefore it is not clear whether its solutions exist globally or blow up in finite time. It is shown in this paper that the solutions exist globally as long as their initial value and the associated boundary data are small, and moreover, those solutions decay exponentially if their boundary data decay exponentially.
Projective-Planar Graphs With No K3,4-Minor,
2011
Wright State University - Main Campus
Projective-Planar Graphs With No K3,4-Minor, John Maharry, Dan Slilaty
Mathematics and Statistics Faculty Publications
An exact structure is described to classify the projective‐planar graphs that do not contain a K3, 4‐minor.
Sharp Asymptotics Of The Lp Approximation Error For Interpolation On Block Partitions,
2011
Kennesaw State University
Sharp Asymptotics Of The Lp Approximation Error For Interpolation On Block Partitions, Yuliya Babenko, Tatyana Leskevich, Jean-Marie Mirebeau
Faculty Articles
Adaptive approximation (or interpolation) takes into account local variations in the behavior of the given function, adjusts the approximant depending on it, and hence yields the smaller error of approximation. The question of constructing optimal approximating spline for each function proved to be very hard. In fact, no polynomial time algorithm of adaptive spline approximation can be designed and no exact formula for the optimal error of approximation can be given. Therefore, the next natural question would be to study the asymptotic behavior of the error and construct asymptotically optimal sequences of partitions. In this paper we provide sharp asymptotic …
Waves In Microstructured Solids: A Unified Viewpoint Of Modelling,
2011
Tallinn University of Technology
Waves In Microstructured Solids: A Unified Viewpoint Of Modelling, Arkadi Berezovski, Juri Engelbrecht, Mihhail Berezovski
Publications
The basic ideas for describing the dispersive wave motion in microstructured solids are discussed in the one-dimensional setting because then the differences between various microstructure models are clearly visible. An overview of models demonstrates a variety of approaches, but the consistent structure of the theory is best considered from the unified viewpoint of internal variables. It is shown that the unification of microstructure models can be achieved using the concept of dual internal variables.
On The Stability Of A Microstructure Model,
2011
Tallinn University of Technology
On The Stability Of A Microstructure Model, Mihhail Berezovski, Arkadi Berezovski
Publications
The asymptotic stability of solutions of the Mindlin-type microstructure model for solids is analyzed in the paper. It is shown that short waves are asymptotically stable even in the case of a weakly non-convex free energy dependence on microdeformation.
Tangential Extremal Principles For Finite And Infinite Systems Of Sets, Ii: Applications To Semi-Infinite And Multiobjective Optimization,
2011
Wayne State University
Tangential Extremal Principles For Finite And Infinite Systems Of Sets, Ii: Applications To Semi-Infinite And Multiobjective Optimization, Boris S. Mordukhovich, Hung M. Phan
Mathematics Research Reports
This paper contains selected applications of the new tangential extremal principles and related results developed in [20] to calculus rules for infinite intersections of sets and optimality conditions for problems of semi-infinite programming and multiobjective optimization with countable constraints.
On The (Non)-Integrability Of The Perturbed Kdv Hierarchy With Generic Self-Consistent Sources,
2011
Bulgarian Academy of Sciences
On The (Non)-Integrability Of The Perturbed Kdv Hierarchy With Generic Self-Consistent Sources, Vladimir Gerdjikov, Georgi Grahovski, Rossen Ivanov
Conference papers
Non-holonomic deformations of integrable equations of the KdV hierarchy are studied by using the expansions over the so-called "squared solutions" (squared eigenfunctions). Such deformations are equivalent to perturbed models with external (self-consistent) sources. In this regard, the KdV6 equation is viewed as a special perturbation of KdV equation. Applying expansions over the symplectic basis of squared eigenfunctions, the integrability properties of the KdV hierarchy with generic self-consistent sources are analyzed. This allows one to formulate a set of conditions on the perturbation terms that preserve the integrability. The perturbation corrections to the scattering data and to the corresponding action-angle variables …
Which Chessboards Have A Closed Knight's Tour Within The Rectangular Prism?,
2011
Kennesaw State University
Which Chessboards Have A Closed Knight's Tour Within The Rectangular Prism?, Joseph Demaio, Mathew Bindia
Faculty Articles
A closed knight's tour of a chessboard uses legal moves of the knight to visit every square exactly once and return to its starting position. In 1991 Schwenk completely classified the m x n rectangular chessboards that admit a closed knight's tour. In honor of the upcoming twentieth anniversary of the publication of Schwenk's paper, this article extends his result by classifying the i x j x k rectangular prisms that admit a closed knight's tour.
Analysis Of The Quasi-Nonlocal Approximation Of Linear And Circular Chains In The Plane,
2011
Augsburg University
Analysis Of The Quasi-Nonlocal Approximation Of Linear And Circular Chains In The Plane, Pavel Bělík, Mitchell Luskin
Faculty Authored Articles
We give an analysis of the stability and displacement error for linear and circular atomistic chains in the plane when the atomistic energy is approximated by the Cauchy-Born continuum energy and by the quasi-nonlocal atomistic-to-continuum coupling energy. We consider atomistic energies that include Lennard-Jones type nearest neighbor and next nearest neighbor pair-potential interactions. Previous analyses for linear chains have shown that the Cauchy-Born and quasi-nonlocal approximations reproduce (up to the order of the lattice spacing) the atomistic lattice stability for perturbations that are constrained to the line of the chain. However, we show that the Cauchy-Born and quasi-nonlocal approximations give …
Error Control Of Iterative Linear Solvers For Integrated Groundwater Models,
2011
University of San Francisco
Error Control Of Iterative Linear Solvers For Integrated Groundwater Models, Matthew Dixon, Z Bai, C F. Brush, F I. Chung, E C. Dogrul, T M. Kadir
Business Analytics and Information Systems
An open problem that arises when using modern iterative linear solvers, such as the preconditioned conjugate gradient method or Generalized Minimum RESidual (GMRES) method, is how to choose the residual tolerance in the linear solver to be consistent with the tolerance on the solution error. This problem is especially acute for integrated groundwater models, which are implicitly coupled to another model, such as surface water models, and resolve both multiple scales of flow and temporal interaction terms, giving rise to linear systems with variable scaling. This article uses the theory of “forward error bound estimation” to explain the correspondence between …
Tangential Extremal Principles For Finite And Infinite Systems Of Sets, I: Basic Theory,
2011
Wayne State University
Tangential Extremal Principles For Finite And Infinite Systems Of Sets, I: Basic Theory, Boris S. Mordukhovich, Hung M. Phan
Mathematics Research Reports
In this paper we develop new extremal principles in variational analysis that deal with finite and infinite systems of convex and nonconvex sets. The results obtained, unified under the name of tangential extremal principles, combine primal and dual approaches to the study of variational systems being in fact first extremal principles applied to infinite systems of sets. The first part of the paper concerns the basic theory of tangential extremal principles while the second part presents applications to problems of semi-infinite programming and multiobjective optimization.
Research In Mathematics Educational Technology: Current Trends And Future Demands,
2011
University of Dayton
Research In Mathematics Educational Technology: Current Trends And Future Demands, Shannon O. Driskell, Robert N. Ronau, Christopher R. Rakes, Sarah B. Bush, Margaret L. Niess, David K. Pugalee
Mathematics Faculty Publications
This systematic review of mathematics educational technology literature identified 1356 manuscripts addressing the integration of educational technology into mathematics instruction. The manuscripts were analyzed using three frameworks (Research Design, Teacher Knowledge, and TPACK) and three supplementary lenses (Data Sources, Outcomes, and NCTM Principles) to produce a database to support future research syntheses and meta-analyses. Preliminary analyses of student and teacher outcomes (e.g., knowledge, cognition, affect, and performance) suggest that the effects of incorporating graphing calculator and dynamic geometry technologies have been abundantly studied; however, the usefulness of the results was often limited by missing information regarding measures of validity, reliability, …
Modeling Diverse Physics Of Nanoparticle Self-Assembly In Pulsed Laser-Irradiated Metallic Films,
2011
Western Kentucky University
Modeling Diverse Physics Of Nanoparticle Self-Assembly In Pulsed Laser-Irradiated Metallic Films, Mikhail Khenner
Mathematics Faculty Publications
Presents physics behind dewetting of thin liquid films and mathematical/computational modeling tools (Educational/Research presentation for senior physics majors).
Stability Of A Strongly Anisotropic Thin Epitaxial Film In A Wetting Interaction With Elastic Substrate,
2011
Western Kentucky University
Stability Of A Strongly Anisotropic Thin Epitaxial Film In A Wetting Interaction With Elastic Substrate, Mikhail Khenner, Wondimu T. Tekalign, Margo S. Levine
Mathematics Faculty Publications
The linear dispersion relation for longwave surface perturbations, as derived by Levine et al. Phys. Rev. B 75, 205312 (2007) is extended to include a smooth surface energy anisotropy function with a variable anisotropy strength (from weak to strong, such that sharp corners and slightly curved facets occur on the corresponding Wulff shape). Through detailed parametric studies it is shown that a combination of a wetting interaction and strong anisotropy, and even a wetting interaction alone results in complicated linear stability characteristics of strained and unstrained films.
Stability Of A Strongly Anisotropic Thin Epitaxial Film In A Wetting Interaction With Elastic Substrate,
2011
Western Kentucky University
Stability Of A Strongly Anisotropic Thin Epitaxial Film In A Wetting Interaction With Elastic Substrate, Mikhail Khenner, Wondimu Tekalign, Margo Levine
Mathematics Faculty Publications
The linear dispersion relation for longwave surface perturbations, as derived by Levine et al. Phys. Rev. B 75, 205312 (2007) is extended to include a smooth surface energy anisotropy function with a variable anisotropy strength (from weak to strong, such that sharp corners and slightly curved facets occur on the corresponding Wulff shape). Through detailed parametric studies it is shown that a combination of a wetting interaction and strong anisotropy, and even a wetting interaction alone results in complicated linear stability characteristics of strained and unstrained films.
Exact Controllability Of A Rayleigh Beam With A Single Boundary Control,
2011
Western Kentucky University
Exact Controllability Of A Rayleigh Beam With A Single Boundary Control, Ahmet Ozkan Ozer, Scott Hansen
Mathematics Faculty Publications
No abstract provided.
