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A Bayesian Late-Fusion Supportability Framework For Rare-Disease Severity Prediction In Glut1 Deficiency Syndrome, Jordan M. Rodriguez 2026 University of Texas at Arlington

A Bayesian Late-Fusion Supportability Framework For Rare-Disease Severity Prediction In Glut1 Deficiency Syndrome, Jordan M. Rodriguez

Mathematics Dissertations

Glucose transporter type 1 deficiency syndrome (GLUT1-DS) is a rare neurometabolic disorder with heterogeneous neurological and developmental severity. Because patient-level severity is not observed as a single validated outcome, this dissertation develops a Bayesian late-fusion supportability framework for constructing and predicting an ordered latent severity phenotype from clinical, genetic, and EEG-derived evidence. The primary target was constructed in a larger clinical cohort using age-5 symptom burden and learning cognition, then assigned to an aligned multimodal prediction cohort. Target-defining variables were excluded from supervised predictors, and models were evaluated using patient-exclusive cross-validation with training-fold preprocessing and fold-wise EEG PCA.

The primary …


The Ellipsoidal Principal Semi-Axis Geometry Of The Solution To An Ivp For A Matrix Diffusion Pde, Brandon M. Fox 2026 University at Albany, State University of New York

The Ellipsoidal Principal Semi-Axis Geometry Of The Solution To An Ivp For A Matrix Diffusion Pde, Brandon M. Fox

Electronic Theses & Dissertations (2024 - present)

We analyze the underlying geometry of the solution to an IVP for a matrix diffusion PDE. We first derive the fundamental solution to the PDE. We then determine the unique solution to the IVP. From there, we begin analyzing its underlying geometry. We first observe that the geometry exhibits an ellipsoidal nature. Furthermore, we observe that it is described by the principal semi-axis geometry of the ellipsoids associated with the solution. This conclusion follows from applying the Principal Axis Theorem to the associated ellipsoids to establish their principal semi-axis geometry, as governed by the eigenstructure of the matrix. This thesis …


Using Feynman's Technique To Evaluate Non-Elementary Integrals Used In Physics, Dominick Dingus, Christopher Wengert, Madouna Barsoum 2025 Lipscomb University

Using Feynman's Technique To Evaluate Non-Elementary Integrals Used In Physics, Dominick Dingus, Christopher Wengert, Madouna Barsoum

Student Scholar Symposium

In numerous physical applications, such as those in the fields of optics and thermodynamics, the quantitative description of various phenomena requires evaluating certain definite integrals whose antiderivatives cannot be expressed using elementary functions. As a result, these integrals are typically evaluated numerically using a suitable program. However, it is possible to evaluate some of these types of integrals using a strategy known as Feynman’s Technique, an approach named after Richard Feynman, the American physicist who popularized the method during the mid-20th century. This project aims to highlight the usage of Feynman’s Technique for evaluating some of these integrals while applying …


Math Meets Climate: The Energy Balance Model, Maria I. Sanchez Muniz 2025 City College of New York

Math Meets Climate: The Energy Balance Model, Maria I. Sanchez Muniz

Open Educational Resources

This assignment introduces students to the mathematics of Earth’s climate through the classical energy balance model. Students analyze how incoming solar radiation, outgoing thermal radiation, and temperature-dependent albedo interact to determine Earth’s equilibrium temperature. Using analytical calculations and computational tools, students identify equilibrium states, assess their stability, and interpret the results through the lens of dynamical systems and bifurcation theory. The activity builds conceptual understanding of climate feedbacks, greenhouse effects, and tipping behavior using a transparent, one-variable model. Designed for applied mathematics and interdisciplinary STEM courses, this assignment emphasizes computation, physical interpretation, and real-world relevance. It is released as a …


Understanding Enso Through Mathematical Models, Maria I. Sanchez Muniz 2025 City College of New York

Understanding Enso Through Mathematical Models, Maria I. Sanchez Muniz

Open Educational Resources

This assignment introduces students to conceptual models of the El Niño–Southern Oscillation (ENSO) and guides them through a structured investigation of their physical and mathematical foundations. Students analyze the recharge–oscillator and delayed–oscillator frameworks, explore how differential equations capture ocean–atmosphere interactions, and evaluate parameter-driven changes in oscillatory behavior. A key component of the work is the guided use of generative AI as a research tool: students employ AI models to locate peer-reviewed literature, interrogate model extensions, and refine their understanding of complex mechanisms, while synthesizing all final explanations in their own words. By blending classical climate modeling with modern AI-supported inquiry, …


Generalizing Threshold-Based Multiparty Computation To Ramp Schemes, Christian Tucker 2025 Clemson University

Generalizing Threshold-Based Multiparty Computation To Ramp Schemes, Christian Tucker

All Theses

Secure multiparty computation (MPC) enables multiple participants to jointly compute functions over their private inputs without revealing them. Classical threshold based protocols, such as the BGW protocol, perform computations on scalar values using (k,n)-threshold secret sharing. While these protocols provide strong security guarantees, they become computationally expensive when applied to large matrices or multiple secret values. In this work, we investigate the use of ramp schemes, secret sharing schemes that encode sets of secrets with a trade-off between privacy and efficiency, to generalize BGW computations. We show that the linear operations performed on shares (k,n)-threshold schemes in BGW can be …


Reverse (Bio)Engineering: A Machine Learning Approach To Optimize Baseball Pitcher Health And Performance, Robert C. Moore 2025 Clemson University

Reverse (Bio)Engineering: A Machine Learning Approach To Optimize Baseball Pitcher Health And Performance, Robert C. Moore

All Dissertations

Ball tracking systems are becoming ubiquitous in sport, creating an unprecedented opportunity for big data applications to optimize human health and performance. These applications are especially common in baseball, a sport known for analyzing ball flight data to quantify performance. Analysts routinely use ball flight data to identify the attributes of top performing pitchers, finding that the best pitchers throw with optimal combinations of release speed and spin to precise locations. However, for certain pitchers, the throwing motion required to produce optimal ball flight places exceedingly high biomechanical load on the elbow, and consequently injury rates continue to rise. This …


Feedback Strategies In The Market With Uncertainties, Mustapha Nyenye Issah 2025 University of South Alabama

Feedback Strategies In The Market With Uncertainties, Mustapha Nyenye Issah

Graduate Theses and Dissertations (2019 - present)

This paper explores how established firms use strategic advertising to deter new competitors in uncertain markets. Specifically, it models a situation where market demand evolves unpredictably - captured by the CKLS stochastic process, and the incumbent firm may be either strong or weak, a fact hidden from potential entrants. For a company already in the market, advertising is not just about driving immediate sales, it is a strategic tool to project an image of strength and deter potential new competitors. On the other side, a business thinking about entering that market faces a high-stakes, irreversible decision. It will typically hold …


Quantum Entanglement As A Resource For Coordinating Navigation, Aamir Ahmad 2025 Florida Institute of Technology

Quantum Entanglement As A Resource For Coordinating Navigation, Aamir Ahmad

Theses and Dissertations

John Clauser, Michael Horne, Abner Shimony, and Richard Holt (CHSH) originally formulated the CHSH game as an experiment to establish entanglement as a quantum mechanical phenomenon that could not be predicted by classical theories. I will apply the quantum strategy used in the CHSH game to demonstrate that it also establishes a structure that employs entanglement as a resource to enable coordination without communication in the context of navigation.


Investigating The Basic Reproduction Number For An Avian Influenza Model, Omar Saucedo 2025 Virginia Polytechnic Institute and State University

Investigating The Basic Reproduction Number For An Avian Influenza Model, Omar Saucedo

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Probabilistic Modeling Of Antibody Kinetics Post Infection And Vaccination, Rayanne Luke, Prajakta Bedekar, Anthony J. Kearsley 2025 George Mason University

Probabilistic Modeling Of Antibody Kinetics Post Infection And Vaccination, Rayanne Luke, Prajakta Bedekar, Anthony J. Kearsley

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


[Project Insight] [Foag] Data-Driven Machine Learning Approaches To Modeling Pertussis Vaccine Scare Behavior, Gleb Gribovskii 2025 University of North Carolina at Greensboro

[Project Insight] [Foag] Data-Driven Machine Learning Approaches To Modeling Pertussis Vaccine Scare Behavior, Gleb Gribovskii

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Histamine And Serotonin Impact Anopheles Stephensi Population Dynamics And Malaria Transmission: Perspectives From Mathematical Modeling, Michael Robert 2025 Virginia Polytechnic Institute and State University

Histamine And Serotonin Impact Anopheles Stephensi Population Dynamics And Malaria Transmission: Perspectives From Mathematical Modeling, Michael Robert

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


The Evolution Of Cooperation In A Mobile Population On Random Networks: Network Topology Matters Only For Low-Degree Networks, Igor V. Erovenko 2025 University of North Carolina at Greensboro

The Evolution Of Cooperation In A Mobile Population On Random Networks: Network Topology Matters Only For Low-Degree Networks, Igor V. Erovenko

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Sustainable Insecticide Spraying Strategy For Long-Term Chagas Disease Vector Control, Bismark Oduro 2025 Pennsylvania Western University

Sustainable Insecticide Spraying Strategy For Long-Term Chagas Disease Vector Control, Bismark Oduro

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Understanding The Spread Of Black Sigatoka Disease: A Deterministic And Stochastic Modeling Approach, Bernard Asamoah Afful, Luis F. Gordillo 2025 Utah State University

Understanding The Spread Of Black Sigatoka Disease: A Deterministic And Stochastic Modeling Approach, Bernard Asamoah Afful, Luis F. Gordillo

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Investigating The Market Dynamics Of Aeroponically Cultivated Products With Delay, Pulak Kundu, Uzzwal Kumar Mallick 2025 Mathematics Discipline, Khulna University, Khulna-9208, Bangladesh

Investigating The Market Dynamics Of Aeroponically Cultivated Products With Delay, Pulak Kundu, Uzzwal Kumar Mallick

Mathematical Modelling and Numerical Simulation with Applications

Aeroponically grown potatoes offer higher yields and year-round production but often face delayed market entry due to high setup costs, technical barriers, and logistical challenges. A delay-based mathematical model has been newly proposed in this study to analyze the dynamics of demand, supply, and pricing for aeroponically grown products. The model’s existence, stability, and sensitivity have been investigated analytically, and numerical simulations have been carried out using the Runge-Kutta 4th order method with the dde23 solver. Findings reveal that market stability is maintained when delays are below seven years, but delays beyond this threshold lead to persistent fluctuations in price, …


Investigating Potential Alzheimer's Disease Therapies Through An Agent-Based Model Of Impaired Microglia Metabolismmodeling Impaired Microglia Metabolism, Cheyenne Ty, Abigail Penland, John Gerving, Martin Mendoza-Ceja, Megan Pratt, Kamila Larripa 2025 Cal Poly Humboldt

Investigating Potential Alzheimer's Disease Therapies Through An Agent-Based Model Of Impaired Microglia Metabolismmodeling Impaired Microglia Metabolism, Cheyenne Ty, Abigail Penland, John Gerving, Martin Mendoza-Ceja, Megan Pratt, Kamila Larripa

Spora: A Journal of Biomathematics

Alzheimer’s disease is the leading cause of dementia globally and is marked by amyloid-β plaque accumulation, decreased brain pH, disrupted metabolism, and increased permeability of the blood-brain barrier. Microglia, the resident immune cells of the central nervous system, are essential for maintaining brain homeostasis and are critically involved in the progression of AD. While microglia can initiate protective immune responses to injury and disease, dysregulated microglial metabolism may contribute to the exacerbation of Alzheimer's pathology. To investigate potential therapeutic strategies, we developed an agent-based model simulating the effects of exercise and metabolic enhancement on dysfunctional microglia. Our findings suggest that …


Building Countably Many Disjoint Stat Sets In Ω1, Jordan Mills 2025 University of Northern Iowa

Building Countably Many Disjoint Stat Sets In Ω1, Jordan Mills

Summer Undergraduate Research Program (SURP) Symposium

The first uncountable ordinal is ω1. Here, we will describe the process for partitioning ω1 into countably many disjoint stationary (stat) sets. We first partition ω1 into 2 disjoint stat sets, and then describe the process for continuing to partition ω1 into infinitely many disjoint stat sets.


Duality Of Quadrilaterals Via Quaternions, Parker Sjomeling 2025 University of Northern Iowa

Duality Of Quadrilaterals Via Quaternions, Parker Sjomeling

Summer Undergraduate Research Program (SURP) Symposium

A quaternion is number which is hyper-complex, it has the form,

Where a₁, a₂, a₃, and a₄ are real “scalars”. Then i, j, and k are imaginary numbers which have the following properties:

q = a1 +a2i + a3j + a3k

Relevant operations on these quaternions include taking the conjugate and the norm (or commonly described as the distance).

The norm of q is equal to:

(a1)2 + (a2)2 + (a3)2 + (a4)2

The conjugate of q is:

¯q = a …


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