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Potential Role Of Rta3 And Gnp3 Transport Genes In The Quorum Sensing Response Of Candida Albicans, John G. Magnuson 2015 East Tennessee State University

Potential Role Of Rta3 And Gnp3 Transport Genes In The Quorum Sensing Response Of Candida Albicans, John G. Magnuson

Undergraduate Honors Theses

Quorum sensing (QS) is a mechanism of communication between cells to coordinate biological activities. In the opportunistic fungal pathogen Candida albicans, QS is important for regulating the organism’s ability to change morphology from a yeast form to a hyphal form. Previously, our laboratory identified several genes involved in polymicrobial communication between C. albicans and three bacterial species. We hypothesize that interspecies communication and QS utilize the same genetic pathways to control C. albicans morphological behavior. In this study, two transport genes, RTA3 and GNP3, and their involvement in QS were examined. To test whether these two genes participate in ...


Identification Of Transcription Factors Gzf3, Rfx1, Orf19.3928 As Being Implicated In Candida-Bacterial Interactions., Joni Watson 2015 East Tennessee State University

Identification Of Transcription Factors Gzf3, Rfx1, Orf19.3928 As Being Implicated In Candida-Bacterial Interactions., Joni Watson

Undergraduate Honors Theses

Candida albicans is an opportunistic pathogen that is present in the normal flora in a majority of individuals. One key factor in C. albicans virulence is the ability to change its morphology from yeast to an elongated or hyphal form. The regulation of this morphogenesis relies in part upon quorum sensing (QS) molecules. C. albicans often exists as part of a mixed culture alongside other microbes and is influenced by their presence as well as the presence of QS molecules that they produce. In this study, a library of diploid homozygous transcriptional regulator knockout (TRKO) mutants were screened to identify ...


Pulmonary Blastomycosis In Vilas County, Wisconsin: Weather, Exposures And Symptoms, Dennis J. Baumgardner, Kiley A. Bernhard, Gina Egan 2015 Aurora Health Care

Pulmonary Blastomycosis In Vilas County, Wisconsin: Weather, Exposures And Symptoms, Dennis J. Baumgardner, Kiley A. Bernhard, Gina Egan

Journal of Patient-Centered Research and Reviews

Purpose

Blastomycosis is a serious fungal infection contracted by inhalation of Blastomyces spores from the environment. Case occurrence in dogs in Vilas County, Wisconsin, has been associated with antecedent weather. We aimed to explore the effects of weather on the occurrence of human pulmonary blastomycosis in this area, and update exposure factors and symptoms since last published reports.

Methods

Mandatory case reports were reviewed. Chi-square test was used for categorical data of exposures, comparing 1979–1996 (n=101) versus 1997–June 2013 (n=95). Linear regression was used to model local weather data (available 1990–2013; n=126); Southern Oscillation ...


Evaluation Of Foliar Fungicides And Insecticides On Soybeans In Northeast Iowa, Daren Mueller, Stith Wiggs, Warren Pierson 2015 Iowa State University

Evaluation Of Foliar Fungicides And Insecticides On Soybeans In Northeast Iowa, Daren Mueller, Stith Wiggs, Warren Pierson

Iowa State Research Farm Progress Reports

Researchers at Iowa State University assessed fungicide and insecticide applications to soybeans at seven locations across Iowa including the Northwest Farm (Sutherland), Northern Farm (Kanawha), Northeast Farm (Nashua), Agronomy Farm (Boone), Armstrong Farm (Lewis), McNay Farm (Chariton), and Southeast Farm (Crawfordsville) (Figure 1).


On-Farm Soybean Fungicide Trials, Jim Fawcett, Lance Miller, Lyle Rossiter, Wayne Roush, Josh Sievers, Micah Smidt, Matt Schnabel 2015 Iowa State University

On-Farm Soybean Fungicide Trials, Jim Fawcett, Lance Miller, Lyle Rossiter, Wayne Roush, Josh Sievers, Micah Smidt, Matt Schnabel

Iowa State Research Farm Progress Reports

Fungicide applications have become more popular among soybean farmers in recent years. The primary use of fungicides has been to control diseases such as Septoria brown spot, Cercospora leaf blight, and frogeye leaf spot. With lower grain prices, the chances of getting an economic benefit from fungicide applications have decreased.


On-Farm Soybean Fungicide Trials, Jim Fawcett, Lance Miller, Lyle Rossiter, Wayne Roush, Josh Sievers, Micah Smidt, Matt Schnabel 2015 Iowa State University

On-Farm Soybean Fungicide Trials, Jim Fawcett, Lance Miller, Lyle Rossiter, Wayne Roush, Josh Sievers, Micah Smidt, Matt Schnabel

Iowa State Research Farm Progress Reports

Fungicide applications have become more popular among soybean farmers in recent years. The primary use of fungicides has been to control diseases such as Septoria brown spot, Cercospora leaf blight, and frogeye leaf spot. With lower grain prices, the chances of getting an economic benefit from fungicide applications have decreased.


Effectiveness Of Foliar Fungicides By Timing On Northern Leaf Blight And Common Rust On Hybrid Corn, Alison Robertson, Josh Sievers, Chad Huffman 2015 Iowa State University

Effectiveness Of Foliar Fungicides By Timing On Northern Leaf Blight And Common Rust On Hybrid Corn, Alison Robertson, Josh Sievers, Chad Huffman

Iowa State Research Farm Progress Reports

Fungicide use on hybrid corn has increased considerably, primarily due to reports of increased yields, even in the absence of disease and higher corn prices. A number of fungicides are registered for use on corn. The objectives of this project were to 1) assess the effect of timing of application of fungicides on disease, 2) evaluate the yield response of hybrid corn to foliar fungicide application, and 3) discern differences, if any, between fungicide products.


On-Farm Corn Fungicide Trials, Jim Fawcett, Lance Miller, Lyle Rossiter, Josh Sievers 2015 Iowa State University

On-Farm Corn Fungicide Trials, Jim Fawcett, Lance Miller, Lyle Rossiter, Josh Sievers

Iowa State Research Farm Progress Reports

An application of fungicide to corn has become a popular input with many farmers in Iowa. The effect of fungicide on corn yield, however, can vary from year to year. Environmental conditions, such as rainfall and temperature, likely are the main factors for differences in how a fungicide affects corn yield because these factors influence disease development and crop growth. Because environmental conditions vary from one year to the next, it is difficult to predict how and when to use a fungicide. Compilation of trial data over many years could help identify factors associated with fungicide response in corn.


On-Farm Soybean Fungicide Trials, Jim Fawcett, Lance Miller, Lyle Rossiter, Wayne Roush, Josh Sievers, Micah Smidt, Matt Schnabel 2015 Iowa State University

On-Farm Soybean Fungicide Trials, Jim Fawcett, Lance Miller, Lyle Rossiter, Wayne Roush, Josh Sievers, Micah Smidt, Matt Schnabel

Iowa State Research Farm Progress Reports

Fungicide applications have become more popular among soybean farmers in recent years. The primary use of fungicides has been to control diseases such as Septoria brown spot, Cercospora leaf blight, and frogeye leaf spot. With lower grain prices, the chances of getting an economic benefit from fungicide applications have decreased.


On-Farm Soybean Fungicide Trials, Jim Fawcett, Lyle Rossiter, Wayne Roush, Josh Sievers, Micah Smidt, Matt Schnabel 2015 Iowa State University

On-Farm Soybean Fungicide Trials, Jim Fawcett, Lyle Rossiter, Wayne Roush, Josh Sievers, Micah Smidt, Matt Schnabel

Iowa State Research Farm Progress Reports

Fungicide applications have become more popular among soybean farmers in recent years. The primary use of fungicides has been to control diseases such as Septoria brown spot, Cercospora leaf blight, and frogeye leaf spot. With lower grain prices, the chances of getting an economic benefit from fungicide applications have decreased.


Evaluation Of Foliar Fungicides And Insecticides On Soybeans In South Central Iowa, Daren Mueller, Stith Wiggs, Warren Pierson 2015 Iowa State University

Evaluation Of Foliar Fungicides And Insecticides On Soybeans In South Central Iowa, Daren Mueller, Stith Wiggs, Warren Pierson

Iowa State Research Farm Progress Reports

Researchers at Iowa State University assessed fungicide and insecticide applications to soybeans at seven locations across Iowa including the Northwest Farm (Sutherland), Northern Farm (Kanawha), Northeast Farm (Nashua), Agronomy Farm (Boone), Armstrong Farm (Lewis), McNay Farm (Chariton), and Southeast Farm (Crawfordsville) (Figure 1).


On-Farm Corn Fungicide Trials, Jim Fawcett, Lance Miller, Lyle Rossiter, Josh Sievers 2015 Iowa State University

On-Farm Corn Fungicide Trials, Jim Fawcett, Lance Miller, Lyle Rossiter, Josh Sievers

Iowa State Research Farm Progress Reports

An application of fungicide to corn has become a popular input with many farmers in Iowa. The effect of fungicide on corn yield, however, can vary from year to year. Environmental conditions, such as rainfall and temperature, likely are the main factors for differences in how a fungicide affects corn yield because these factors influence disease development and crop growth. Because environmental conditions vary from one year to the next, it is difficult to predict how and when to use a fungicide. Compilation of trial data over many years could help identify factors associated with fungicide response in corn.


Evaluation Of Foliar Fungicides And Insecticides On Soybeans In Central Iowa, Daren Mueller, Stith Wiggs, Warren Pierson 2015 Iowa State University

Evaluation Of Foliar Fungicides And Insecticides On Soybeans In Central Iowa, Daren Mueller, Stith Wiggs, Warren Pierson

Iowa State Research Farm Progress Reports

Researchers at Iowa State University assessed fungicide and insecticide applications to soybeans at seven locations across Iowa including the Northwest Farm (Sutherland), Northern Farm (Kanawha), Northeast Farm (Nashua), Agronomy Farm (Boone), Armstrong Farm (Lewis), McNay Farm (Chariton), and Southeast Farm (Crawfordsville) (Figure 1).


Effectiveness Of Foliar Fungicides By Timing On Northern Leaf Blight On Hybrid Corn In Southeast Iowa, Alison Robertson, Myron Rees 2015 Iowa State University

Effectiveness Of Foliar Fungicides By Timing On Northern Leaf Blight On Hybrid Corn In Southeast Iowa, Alison Robertson, Myron Rees

Iowa State Research Farm Progress Reports

Fungicide use on hybrid corn has increased considerably, primarily due to reports of increased yields, even in the absence of disease and higher corn prices. A number of fungicides are registered for use on corn. The objectives of this project were to 1) assess the effect of timing of application of fungicides on disease, 2) evaluate the yield response of hybrid corn to foliar fungicide application, and 3) discern differences, if any, between fungicide products.


Evaluation Of Foliar Fungicides And Insecticides On Soybeans In Southeast Iowa, Daren Mueller, Stith Wiggs, Warren Pierson 2015 Iowa State University

Evaluation Of Foliar Fungicides And Insecticides On Soybeans In Southeast Iowa, Daren Mueller, Stith Wiggs, Warren Pierson

Iowa State Research Farm Progress Reports

Researchers at Iowa State University assessed fungicide and insecticide applications to soybeans at seven locations across Iowa including the Northwest Farm (Sutherland), Northern Farm (Kanawha), Northeast Farm (Nashua), Agronomy Farm (Boone), Armstrong Farm (Lewis), McNay Farm (Chariton), and Southeast Farm (Crawfordsville) (Figure 1).


On-Farm Soybean Fungicide Trials, Jim Fawcett, Lance Miller, Lyle Rossiter, Wayne Roush, Josh Sievers, Micah Smidt, Matt Schnabel 2015 Iowa State University

On-Farm Soybean Fungicide Trials, Jim Fawcett, Lance Miller, Lyle Rossiter, Wayne Roush, Josh Sievers, Micah Smidt, Matt Schnabel

Iowa State Research Farm Progress Reports

Fungicide applications have become more popular among soybean farmers in recent years. The primary use of fungicides has been to control diseases such as Septoria brown spot, Cercospora leaf blight, and frogeye leaf spot. With lower grain prices, the chances of getting an economic benefit from fungicide applications have decreased.


Effectiveness Of Foliar Fungicides By Timing On Northern Leaf Blight On Hybrid Corn In Northeast Iowa, Alison Robertson, Kenneth Pecinovsky 2015 Iowa State University

Effectiveness Of Foliar Fungicides By Timing On Northern Leaf Blight On Hybrid Corn In Northeast Iowa, Alison Robertson, Kenneth Pecinovsky

Iowa State Research Farm Progress Reports

Fungicide use on hybrid corn has increased considerably, primarily due to reports of increased yields, even in the absence of disease and higher corn prices. A number of fungicides are registered for use on corn. The objectives of this project were to 1) assess the effect of timing of application of fungicides on disease, 2) evaluate the yield response of hybrid corn to foliar fungicide application, and 3) discern differences, if any, between fungicide products.


Effectiveness Of Foliar Fungicides By Timing On Northern Leaf Blight On Hybrid Corn In Southwest Iowa, Alison Robertson, Bernie Havlovic, Dan Schaben 2015 Iowa State University

Effectiveness Of Foliar Fungicides By Timing On Northern Leaf Blight On Hybrid Corn In Southwest Iowa, Alison Robertson, Bernie Havlovic, Dan Schaben

Iowa State Research Farm Progress Reports

Fungicide use on hybrid corn has increased considerably, primarily due to reports of increased yields, even in the absence of disease and higher corn prices. A number of fungicides are registered for use on corn. The objectives of this project were to 1) assess the effect of timing of application of fungicides on disease, 2) evaluate the yield response of hybrid corn to foliar fungicide application, and 3) discern differences, if any, between fungicide products.


Characterization Of A Novel Fungal-Specific Gene, Fug1, In Fusarium Verticillioides, John Byron Ridenour 2014 University of Arkansas, Fayetteville

Characterization Of A Novel Fungal-Specific Gene, Fug1, In Fusarium Verticillioides, John Byron Ridenour

Theses and Dissertations

Filamentous fungi are responsible for numerous plant and animal diseases. The filamentous ascomycete Fusarium verticillioides is a globally important pathogen of maize, capable of causing severe yield reductions and economic losses. Also of substantial concern is the contamination of infected kernels with fumonisins, toxic secondary metabolites linked to toxicoses in humans and livestock. The number of sequenced fungal genomes is rapidly increasing. However, functional characterization of fungal genes has not progressed at a comparable rate. In pathogenic fungi, uncharacterized genes represent a source for novel virulence factors or anti-fungal targets. Therefore, to fully understand the genetic mechanisms underlying fungal pathogenesis ...


Characterization And Quantification Of The Fungal Microbiome In Serial Samples From Individuals With Cystic Fibrosis, Sven D. Willger, Sharon L. Grim, Emily L. Dolben, Anna Shipunova, Thomas H. Hampton, Hillary G. Morrison, Laura M. Filkins, George A. O'Toole, Lisa A. Moulton, Alix Ashare, Mitchell L. Sogin, Deborah A. Hogan 2014 Dartmouth College

Characterization And Quantification Of The Fungal Microbiome In Serial Samples From Individuals With Cystic Fibrosis, Sven D. Willger, Sharon L. Grim, Emily L. Dolben, Anna Shipunova, Thomas H. Hampton, Hillary G. Morrison, Laura M. Filkins, George A. O'Toole, Lisa A. Moulton, Alix Ashare, Mitchell L. Sogin, Deborah A. Hogan

Dartmouth Scholarship

Background: Human-associated microbial communities include fungi, but we understand little about which fungal species are present, their relative and absolute abundances, and how antimicrobial therapy impacts fungal communities. The disease cystic fibrosis (CF) often involves chronic airway colonization by bacteria and fungi, and these infections cause irreversible lung damage. Fungi are detected more frequently in CF sputum samples upon initiation of antimicrobial therapy, and several studies have implicated the detection of fungi in sputum with worse outcomes. Thus, a more complete understanding of fungi in CF is required. Results: We characterized the fungi and bacteria in expectorated sputa from six ...


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