Dentistry Commons^™

Oral Health Knowledge, Attitudes, And Practices Among Secondary School Students In Nigeria, Johnson John Omale

Walden Dissertations and Doctoral Studies

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Regulatory Control Of Palatogenesis And Odontogenesis By Specificity Protein 7, John Christopher Clarke

All ETDs from UAB

Runx2 and its downstream target Specificity Protein 7 (Sp7) are essential for skeletogenesis. In humans, mutations in Sp7 gene are associated with osteogenesis imperfecta. Unlike Runx2, the role of Sp7 in palatogenesis, tooth development or differentiation of ameloblasts and odontoblasts remains unknown. The main goal of this research was to identify the functional requirement of Sp7 transcription factor during tooth development and palatogenesis. Molecular, biochemical, and histological approaches were employed to answer this question. We established Sp7-null mice that are completely void of mineralized tissue, exhibit craniofacial dysmorphogenesis and die shortly after birth. Surprisingly, Sp7 homozygous mutants exhibited normal tooth …

Clinical Evaluation Of Non-Carious Cervical Lesions- A Five Year Prospective Evaluation, Kanchan Sawlani

All ETDs from UAB

Non-carious cervical lesions (NCCLs) have a non-bacterial origin and produce a loss of tooth structure at the cemento-enamel junction. A review of the literature reveals that these lesions may have a multifactorial etiology (chemical, abrasion, abfraction). The role of heavy biting forces in the pathogenesis of NCCLs is yet to be firmly established. Treatment and preventive measures for NCCLs can be improved if the etiology can be clearly identified and treated.Objective: This prospective clinical trial measured the volume loss (increase in size) of NCCLs and the occlusal biting forces applied to these teeth; diet and tooth brushing analysis, followed by …

Effect Of Cad/Cam Processing On Esthetic Characteristics Of Porcelain Veneers, Eduardo Cortes-Contreras

Student Theses, Dissertations and Capstones

Introduction: Dentistry has changed significantly during the last two decades. Patients are more aware and demanding of the latest technologies available in restorative dentistry. The purpose of this study was to determine any possible changes on the surface roughness, gloss and color change of CAD-CAM milled porcelain veneers following repeated milling times, before and after a glazing process. Methods: A Teflon disk-shaped mold was used as a cast to take a digital impression (BlueCam) in order to fabricate cylindrical-shaped specimens. A total of one hundred (N=100) specimens porcelain veneers using Empress CAD (I10) block, were milled using the CAD/CAM CEREC-SIRONA …

Cephalometric Regional Superimpositions -- Digital Vs. Analog Accuracy And Precision : 3. The Cranial Base, Douglas Shaw

Student Theses, Dissertations and Capstones

Objective. To assess the accuracy and precision in measurement of pairwise implant displacement across three methods of cranial base superimposition. Background. Cephalometric superimposition is the principal radiographic method used to evaluate changes within the craniofacial skeleton. Many studies have examined the accuracy of software intended to produce cephalometric superimposition. Such studies have utilized anatomic landmarks, selected by the respective software manufacturers, as registration points for constructing superimpositions and their analysis. As a result, these studies are only as accurate as the stability and validity of anatomic registration landmarks used. To our knowledge, no other study has utilized metallic implants to …

Influence Of Immediate Dentin Sealing On The Bond Strength Of Indirect Bonded Restorations, Alexander Duque

Student Theses, Dissertations and Capstones

Introduction: A critical issue and concern that has been documented in dentistry is the complexity of bonding to dentin, a fact that has been referred to as a less reliable technique due to the intrinsic characteristics of the dentin substrate. Effectiveness on dentin bonding is a clinical important approach for indirect bonded restorations in order to achieve a good adhesion that can surpass the test of time. Long-term clinical trials have shown that indirect bonded restorations have an increased risk of failure when using dentin as the major substrate. Consequently, an effort should be made to improve techniques and materials …

In Vitro Comparison Of Force Decay Between Three Orthodontic Sliding Retraction Methods, Pamela Steiger

Student Theses, Dissertations and Capstones

Objective: The purpose of this in vitro study was to determine if there is a difference in force decay between three sliding retraction methods under a standardized force delivery system (200 gm at 25 mm stretch) at 2, 4, 6, and 8 weeks. Background: In order to achieve proper esthetics, occlusion and stability, orthodontic treatment may require extractions. Elastomeric chains, Nickel Titanium (NiTi) coils, and active ligatures are commonly used to close these extraction spaces. Methods: Twenty samples of each retraction method (elastomeric chains, NiTi Coils and active ligatures) were evaluated under standardized conditions (200 gm at 25 mm). The …

Effect Of Resin Cement, Aging Process And Root Level On The Bond Strength Of The Resin-Fiber Posts, Khalid Almulhim

Student Theses, Dissertations and Capstones

Background . Little is known about the long-term clinical bonding effectiveness of the Fiber-reinforced composite (FRC) posts cemented with self-etch adhesive systems. Bond stability and longevity of the cemented post are adversely affected by physical and chemical factors over time, such as expansion and contraction stresses caused by thermal changes and occlusal load. This clinical condition can be simulated in vitro by thermocyclic loading; and bonding effectiveness can be evaluated by applying the micropush out test. Therefore, more in vitro studies are needed to evaluate the bond strength of the fiber posts cemented with different resin cement systems after simulating …

Human Gingival Mesenchymal Stem Cells And Self-Assembling Peptide Puramatrix(Tm) Scaffold For Bone Formation, Don Do

Student Theses, Dissertations and Capstones

A thesis submitted to the College of Dental Medicine of Nova Southeastern University of the degree of Master of Science in Dentistry.

Purpose: Among various craniofacial defects, cleft palate is the most common congenital birth defect. Reconstruction of bony parts in the hard palate is important to preserve normal craniofacial growth. Autologous bone grafting is associated with donor site morbidity, extensive healing time, and scar formation. Tissue engineering techniques remain a viable option for the repair and reconstruction of bone. In this study, human gingiva-derived mesenchymal stem cells (HGMSCs) were used in combination with a self-assembled injectable hydrogel scaffold PuraMatrixTM …

Evaluation Of The Effect Of Enamel Deproteinization On Shear Bond Strength Of Orthodontic Adhesives And Resulting White Spot Lesion Formation, Kelly Chioffe

Student Theses, Dissertations and Capstones

A thesis submitted to the College of Dental Medicine of Nova Southeastern University of the degree of Master of Science in Dentistry.

Objective: The objectives of this study were 1) to evaluate the effect of enamel deproteinization on the shear bond strength(SBS) of orthodontic brackets bonded with a resin modified glass-ionomer (RMGI) adhesive and a composite resin, 2) to determine the mode of bond failure according to the adhesive remnant index (ARI) and 3) to evaluate the effect of these adhesives in the prevention of white spot lesions (WSLs). Background: WSLs are a concern for orthodontic patients. RMGI orthodontic adhesives …

Cephalometric Regional Superimpositions -- Digital Vs. Analog Accuracy And Precision : 1. The Maxilla, Glenn Krieger

Student Theses, Dissertations and Capstones

Introduction: The purpose of this study was to measure the displacement of defined dental structures, as a result of superimposition of cephalometric images across paired time-points by both digital and analog methods. The magnitudes of such displacements across three methods of superimposition were compared to each other and to a reference method constructed by registering superimposed cephalometric images on tantalum markers implanted in the study participants' maxillae. The defined dental structures were: 1) First molar mesial contact point; 2) First molar apical root bisection; 3) Central incisor root apex; 4) Central incisor crown incisal edge. Methods: Lateral cephalograms of 22 …

Bmp2 Induced Osteogenic Differentiation Of Human Umbilical Cord Stem Cells In A Peptide-Based Hydrogel Scaffold, Shruthi Lakshmana

Student Theses, Dissertations and Capstones

Craniofacial tissue loss due to traumatic injuries and congenital defects is a major clinical problem around the world. Cleft palate is the second most common congenital malformation in the United States occurring with an incidence of 1 in 700. Some of the problems associated with this defect are feeding difficulties, speech abnormalities and dentofacial anomalies. Current treatment protocol offers repeated surgeries with extended healing time. Our long-term goal is to regenerate bone in the palatal region using tissue-engineering approaches. Bone tissue engineering utilizes osteogenic cells, osteoconductive scaffolds and osteoinductive signals. Mesenchymal stem cells derived from human umbilical cord (HUMSCs) are …

Operative Management Of Idiophatic Myositis Ossificans Of Lateral Pterygoid Muscle, Luis Eduardo Almeida, Andrea Doetzer, Flavio Camejo, Jose A. Bosio

School of Dentistry Faculty Research and Publications

INTRODUCTION

Myositis ossificans (MO) is characterized as heterotopic bone formation within muscle. MO rarely occurs in the head and neck region. Excision of the heterotopic bone is the standard treatment. This report summarizes a case of a 12-year old female with MO involving the lateral pterygoid muscle. The heterotopic bone was excised using an intraoral incision. Despite intensive physical therapy, the operation failed as evidenced by new bone formation in the area within three weeks of the operation.

PRESENTATION OF CASE

A twelve years old female patient presenting with mouth opening of 10 mm, no facial asymmetry, and no jaw …

Patterns Of Dental Service Utilization Following Nontraumatic Dental Condition Visits To The Emergency Department In Wisconsin Medicaid, Nicholas M. Pajewski, Christopher Okunseri

School of Dentistry Faculty Research and Publications

Objectives: To examine patterns of dental service utilization for adult Medicaid enrollees in Wisconsin following nontraumatic dental condition (NTDC) visits to the emergency department (ED).

Methods: This is a retrospective, observational study of claims for NTDC visits to the ED and dental service encounters from the Wisconsin Medicaid Evaluation and Decision Support database (2001-2009). We used competing risk models to predict probabilities of returning to the ED versus obtaining follow-up care from a dentist.

Results: We observed a 43 percent increase in the rate of NTDC visits to the ED, with most of this increase occurring from 2001 to 2005. …

A Prospective Study Of Periodontal Disease And Risk Of Gastric And Duodenal Ulcer In Male Health Professionals, Matthew R. Boylan, Hamed Khalili, Edward S. Huang, Dominique S. Michaud, Jacques Izard, Kaumudi J. Joshipura, Andrew T. Chan

Department of Food Science and Technology: Faculty Publications

Periodontal disease is characterized by microbial shifts within the oral cavity and chronic inflammation of the gingival tissue, and can lead to tooth loss. Several studies support an association between periodontal disease and risk of chronic systemic conditions, including vascular disease, chronic obstructive pulmonary disease, diabetes mellitus, and cancer, including gastric adenocarcinoma. These associations may be mediated by systemic inflammation, the immune response to periodontal infection, or direct invasion by pathogens. Previous studies of periodontal disease and risk of peptic ulcer have been limited by cross-sectional design, diagnoses that were not confirmed by medical record review, and a lack of …

Oral Health Literacy Of Parents And Dental Service Use For Children Enrolled In Medicaid, Angel Smith

Walden Dissertations and Doctoral Studies

Many people in the United States have untreated dental disease due to a lack of dental insurance, a lack of oral health knowledge, and a lack of priority placed on dental health. Despite an increase in dental service use by Medicaid recipients as a result of local programs, children enrolled in Medicaid often have low rates of use of dental services. Using the health literacy framework of the Paasche-Orlow and Wolf (POW) model, the purpose of this study was to explore to the relationship between oral health literacy of parents and dental service use for children enrolled in Medicaid and …

Effect Of Jagged-1 And Delta-Like1 On The Proliferation And Osteogenic Differentiation Of Primary Deciduous Pulp Cells, Karnnapas Peetiakarawach

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objectives: The purpose of the present study was to investigate the influence of Notch ligands, Jagged-1 and Delta-like1, on the proliferation and osteogenic differentiation of primary deciduous pulp cells in vitro. Methods: Jagged-1 and Delta-like1 ligands were immobilized to the tissue culture surface using indirect affinity immobilization technique. Cell proliferation was determined by a MTT assay and the mRNA expression levels of apoptosis related-genes. The osteogenic differentiation was determined by the ALP activity assay, the mineralization assay, and the mRNA expression levels of osteogenic genes. Statistical analyses were performed using Kruskal-Wallis H followed by Mann-Whitney U. Results: Cell proliferation was …

Surface Roughness Of Feldspathic Porcelain Polished With Alumina-Zirconia Paste, ศุภรักษ์ ยมกกุล

Chulalongkorn University Theses and Dissertations (Chula ETD)

The purpose of this study was to develop a new polishing paste composed of zirconia that was leftover from the zirconia crown/bridge fabrication process that is as effective as diamond paste when used to polish feldspathic porcelain. This study was divided into two parts. First part was to study the surface roughness of feldspathic porcelain after polishing with diamond, alumina, zirconia and alumina-zirconia paste. The result showed that porcelain polished with zirconia paste had the highest mean Ra value, porcelains polished with alumina and alumina-zirconia paste had lower Ra values than zirconia paste while porcelain polished weight diamond paste demonstrated …

ความแข็งแรงยึดติดแบบเฉือนระดับจุลภาคของสารยึดติดระบบยูนิเวอร์แซลต่อเนื้อฟันน้ำนม, เบญจพร ธนรติกุล

Chulalongkorn University Theses and Dissertations (Chula ETD)

วัตถุประสงค์ เพื่อประเมินค่าความแข็งแรงยึดติดแบบเฉือนระดับจุลภาคของสารเรซินคอมโพสิตต่อเนื้อฟันน้ำนมเมื่อนำสารยูนิเวอร์แซลแอดฮีซีฟมาใช้ในวิธีการของเอทช์แอนด์รินซ์และเซลฟ์เอทช์ วัสดุและวิธีการ ฟันหน้าตัดน้ำนมของมนุษย์จำนวน 40 ซี่ นำมาขัดผิวด้านริมฝีปากเพื่อให้เกิดพื้นที่เรียบของผิวเนื้อฟัน แบ่งกลุ่มอย่างสุ่มออกเป็น 4 กลุ่ม กลุ่มละ 10 ซี่ ตามชนิดและวิธีการใช้งานของสารยึดติด คือ สารแอดเพอร์ซิงเกิลบอนด์ทู (เอทช์แอนด์รินซ์แบบสองขั้นตอน) สารเคลียร์ฟิลเอสอีบอนด์ (เซลฟ์เอทช์แบบสองขั้นตอน) และสารซิงเกิลบอนด์ยูนิเวอร์แซล (เอทช์แอนด์รินซ์แบบสองขั้นตอนและเซลฟ์เอทช์แบบหนึ่งขั้นตอน) โดยฟันแต่ละซี่จะทำการยึดติดและอุดด้วยวัสดุเรซินคอมโพสิตตามคำแนะนำการใช้งานของบริษัทผู้ผลิต นำชิ้นงานที่ได้ไปแช่ในน้ำกลั่นที่อุณหภูมิ 37 องศาเซลเซียส เป็นเวลา 24 ชั่วโมง แล้วจึงนำมาทดสอบความแข็งแรงแบบเฉือนระดับจุลภาคที่ความเร็วหัวกด 1 มิลลิเมตรต่อนาทีจนเกิดการแตกหัก แล้วทำการตรวจสอบลักษณะความล้มเหลวในการยึดติดด้วยกล้องจุลทรรศน์อิเล็กตรอนแบบส่องกราด ผลการทดลอง สารแอดเพอร์ซิงเกิลบอนด์ทูมีค่าความแข็งแรงยึดติดเฉลี่ย (19.1 ± 3.4 เมกะพาสคาล) น้อยกว่าสารซิงเกิลบอนด์ยูนิเวอร์แซลที่นำมาใช้ในวิธีการของเอทช์แอนด์รินซ์ (24.3 ± 2.7 เมกะพาสคาล) อย่างมีนัยสำคัญ แต่เมื่อเปรียบเทียบการใช้งานในระบบเซลฟ์เอทช์ พบว่าสารเคลียร์ฟิลเอสอีบอนด์และสารซิงเกิลบอนด์ยูนิเวอร์แซลให้ค่าความแข็งแรงยึดติดแบบเฉือนระดับจุลภาคไม่แตกต่างกัน (25.3 ± 2.7 และ 25.1 ± 2.3 เมกะพาสคาล ตามลำดับ) ซึ่งลักษณะความล้มเหลวส่วนใหญ่ที่พบ เกิดบริเวณรอยต่อของเนื้อฟันกับสารยึดติดในทุกกลุ่มการทดลอง สรุป วิธีการใช้งานทั้งแบบเอทช์แอนด์รินซ์และเซลฟ์เอทช์ของสารซิงเกิลบอนด์ยูนิเวอร์แซลให้ค่าความแข็งแรงยึดติดที่ดีไม่ต่างกันบนผิวเนื้อฟันน้ำนม ส่วนบริเวณรอยต่อที่มีการยึดติดในแต่ละกลุ่มจะมีความแตกต่างกันไปตามค่าความเป็นกรดด่างและวิธีการการยึดติดที่ใช้

Effect Of Curcumin On Tnf-Α-Induced Cyclooxygenase-2 Gene Expression And Prostaglandin E2 Synthesis In Bone Marrow Stromal Cell Line, Varittha Thongtan

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objective of this study was to investigate the effect of curcumin on TNF-α-induced expression of COX-2 and PGE2 synthesis in mouse ST2 bone marrow-derived stromal cells. ST2 cells were treated with TNF-α to determine the optimum concentration and treatment duration for inducing COX-2 expression. Then, ST2 cells were treated with TNF-α in the absence or presence of various concentration of curcumin. COX-2 expression was determined using reverse transcriptase polymerase chain reaction and PGE2 level in culture medium was measured using ELISA. TNF-α at concentrations of 1-50 ng/mL significantly increased COX-2 expression, with the maximum induction at 20 ng/mL. The …