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Immediate And Early Loading Of Hydrothermally Treated, Hydroxyapatite-Coated Dental Implants: A 7-Year Prospective Randomized Clinical Study, Afarin Arghami, David Simmons, Jeanne St Germain, Pooja Maney 2021 LSU Health Sciences Center - New Orleans

Immediate And Early Loading Of Hydrothermally Treated, Hydroxyapatite-Coated Dental Implants: A 7-Year Prospective Randomized Clinical Study, Afarin Arghami, David Simmons, Jeanne St Germain, Pooja Maney

School of Dentistry Faculty Publications

Background Existing research on marginal bone stability around hydroxyapatite (HA)-coated implants often lacks adequate long-term follow-up. The purpose of this randomized prospective study was to evaluate the 7-year outcome of patients with immediate and early loaded single-tooth restorations supported by implants with plasma-sprayed, partially HA-coated surfaces. Forty-two patients in need of 50 single implants were treated in in the Postgraduate Periodontics Clinic of Louisiana State University School of Dentistry. Implants were randomly divided into 2 groups: Group A was immediately loaded, and Group B was early loaded. Continuous follow-up with periodic maintenance care and radiographic evaluations was performed. The primary …


Ada News - 03/08/2021, American Dental Association, Publishing Division 2021 American Dental Association

Ada News - 03/08/2021, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.


Dental Practice Success Special Issue: Financial Foundations For The New Dentist (March 2021), American Dental Association, Publishing Division 2021 American Dental Association

Dental Practice Success Special Issue: Financial Foundations For The New Dentist (March 2021), American Dental Association, Publishing Division

Dental Practice Success

No abstract provided.


New Dentist News (March 2021), ADA Committee on the New Dentist 2021 American Dental Association

New Dentist News (March 2021), Ada Committee On The New Dentist

New Dentist News

New Dentist News offers timely information on scientific, social, educational, political and economic developments affecting new dentists. This collection is historical and items may not reflect current standards. For up-to-date information contact the ADA. The New Dentist News was alternately titled ADA Lifeline, 1997-June 2001.


Does Covid-19 Contribute To Development Of Neurological Disease?, Arehally M. Mahalakshmi, Bipul Ray, Sunanda Tuladhar, Abid Bhat, Shasthara Paneyala, Duraisamy Patteswari, Meena Kishore Sakharkar, Hamdan Hamdan, David M. Ojcius, Srinivasa Rao Bolla, Musthafa Mohamed Essa, Saravana Babu Chidambaram, M. Walid Qoronfleh 2021 JSS College of Pharmacy, Mysore

Does Covid-19 Contribute To Development Of Neurological Disease?, Arehally M. Mahalakshmi, Bipul Ray, Sunanda Tuladhar, Abid Bhat, Shasthara Paneyala, Duraisamy Patteswari, Meena Kishore Sakharkar, Hamdan Hamdan, David M. Ojcius, Srinivasa Rao Bolla, Musthafa Mohamed Essa, Saravana Babu Chidambaram, M. Walid Qoronfleh

All Dugoni School of Dentistry Faculty Articles

Background: Although coronavirus disease 2019 (COVID-19) has been associated primarily with pneumonia, recent data show that the causative agent of COVID-19, the coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can infect a large number of vital organs beyond the lungs, such as the heart, kidneys, and the brain. Thus, there is evidence showing possible retrograde transmission of the virus from the olfactory epithelium to regions of the brain stem. Methods: This is a literature review article. The research design method is an evidence-based rapid review. The present discourse aim is first to scrutinize and assess the available literature on …


Comparison Of Two Different Methods In The Removal Of Oil-Based Calcium Hydroxide From Root Canal System: A Triple-Blinded Randomised Clinical Trial, Momina Motiwala, Sheikh Bilal Badar, Rabia Ghafoor 2021 Aga Khan University

Comparison Of Two Different Methods In The Removal Of Oil-Based Calcium Hydroxide From Root Canal System: A Triple-Blinded Randomised Clinical Trial, Momina Motiwala, Sheikh Bilal Badar, Rabia Ghafoor

Section of Dental-Oral Maxillofacial Surgery

Objective: To compare the effectiveness of rotary master apical file (RMAF) with ultrasonic activation of endodontic file (UAF) in the removal of silicon oil-based calcium hydroxide (SOBCH) from the canal.
Methods: Ethical review committee approval and informed consent was obtained. 60 cases with necrotic teeth in which silicon oil-based intracanal medicament (Metapex) was to be placed were randomised in one of the two groups using sealed envelopes containing assignment codes for medicament removal: RMAF and UAF group. After standard protocol of coronal access, cleaning and shaping, silicon oil-based SOBCH was placed using a Lentulo spiral. A periapical radiograph was taken …


Relationship Of Natural Occlusal Plane With Different Anatomical Landmarks, Mehwish Khan, Syed Murtaza Raza Kazmi, Farhan Raza Khan, Sameer Quraeshi 2021 Jinnah Sindh Medical University, Karachi, Pakistan

Relationship Of Natural Occlusal Plane With Different Anatomical Landmarks, Mehwish Khan, Syed Murtaza Raza Kazmi, Farhan Raza Khan, Sameer Quraeshi

Section of Dental-Oral Maxillofacial Surgery

Objective: To evaluate the parallelism of natural maxillary occlusal plane with inter-pupillary line and ala-tragus line, and to evaluate the anatomic relationship of natural mandibular occlusal plane with retromolar pad among dentate subjects.
Methods: The cross-sectional study was conducted from September 2017 to February 2018 at Fatima Jinnah Dental College, Karachi, and comprised front and profile photographs of subjects aged 20-28 years while holding the camper's plane against the maxillary occlusal plane. The photographs were imported in a software and an interpupillary line was drawn and the angle with Camper's plane was measured. On both profile pictures, lines were drawn …


N Y State Dent J March 2021, 2021 American Dental Association

N Y State Dent J March 2021

The New York State Dental Journal

The New York State Dental Journal (NYSDJ) is produced by the New York State Dental Association (NYSDA) six times a year, in January, March, April, July, September and November. Each issue features clinical and scientific articles written by researchers and practitioners from around the globe and is subject to review by a panel of specialists convened by the Editor.

Issues include cover and feature articles alongside regular columns with regional news impacting the New York membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.


Osteogenic Differentiation Of Adipose-Derived Mesenchymal Stem Cells Using 3d-Printed Pdlla/ Β-Tcp Nanocomposite Scaffolds, Ashkan Bigham, Amir Hamed Aghajanian, Mehdi Movahedi, Mansoureh Sattary, Mohammad Rafienia, Lobat Tayebi 2021 Isfahan University of Medical Sciences

Osteogenic Differentiation Of Adipose-Derived Mesenchymal Stem Cells Using 3d-Printed Pdlla/ Β-Tcp Nanocomposite Scaffolds, Ashkan Bigham, Amir Hamed Aghajanian, Mehdi Movahedi, Mansoureh Sattary, Mohammad Rafienia, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Designing bone scaffolds containing both organic and inorganic composites simulating the architecture of the bone is the most important principle in bone tissue engineering. The objective of this study was to fabricate a composite scaffold containing poly (D, l)-lactide (PDLLA) and β-tricalcium phosphate (β-TCP) as a platform for osteogenic differentiation of adipose-derived mesenchymal stem cells. In this study, PDLLA/β-TCP scaffolds were fabricated using three-dimensional printing (3D) technology through melt excursion technique. The physicomechanical characteristics, including microstructure, mechanical properties, of the customized scaffolds were investigated. Further, the in vitro biological characteristics of manufactured scaffolds were evaluated in conjugation with buccal fat …


J Mich Dent Assoc March 2021, 2021 American Dental Association

J Mich Dent Assoc March 2021

The Journal of the Michigan Dental Association

Every month, The Journal of the Michigan Dental Association brings news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. No publication reaches more Michigan dentists!

In this issue, the reader will find the following original content:

  • A cover story, “Vaccination by Dentists: Integrating Vaccination into Dental Practice”.
  • A feature article on “Creating Opportunities for HPV Awareness and Prevention in Dental Health Care Settings”.
  • The feature article, “MDA Legislative Advocacy 2021: What We’ve Done and What’s to Come”.
  • “How COVID-19 Has Impacted Michigan Dentists”, a feature article.
  • News you need, Editorial and …


Management Of Difficult Airway In A Pregnant Patient With Severely Reduced Mouth Opening, Faisal Shamim, Aly Bahadur, Dinaz Ghandhi, Anum Aijaz 2021 Aga Khan University

Management Of Difficult Airway In A Pregnant Patient With Severely Reduced Mouth Opening, Faisal Shamim, Aly Bahadur, Dinaz Ghandhi, Anum Aijaz

Department of Anaesthesia

Pregnancy is associated with a wide variety of oral and dental changes ranging from gingivitis to odontogenic infections. If left untreated, severe dental abscess can progress to Ludwig's angina, which is a potentially lethal cellulitis that rapidly extends to the neck region and may lead to life-threatening upper airway obstruction. We report the case of a pregnant woman who presented with intense throbbing pain, trismus and severely reduced mouth opening due to dental abscess for the last one week. She required incision and drainage of abscess with extraction of third molar under general anaesthesia. There are some significant challenges to …


Polymeric Nanoparticles For Nasal Drug Delivery To The Brain: Relevance To Alzheimer's Disease, Navid Rabiee, Sepideh Ahmadi, Ronak Afshari, Samira Khalaji, Mohammad Rabiee, Mojtaba Bagherzadeh, Yousef Fatahi, Rassoul Dinarvand, Mohammadreza Tahriri, Lobat Tayebi, Michael R. Hamblin, Thomas J. Webster 2021 Sharif University of Technology

Polymeric Nanoparticles For Nasal Drug Delivery To The Brain: Relevance To Alzheimer's Disease, Navid Rabiee, Sepideh Ahmadi, Ronak Afshari, Samira Khalaji, Mohammad Rabiee, Mojtaba Bagherzadeh, Yousef Fatahi, Rassoul Dinarvand, Mohammadreza Tahriri, Lobat Tayebi, Michael R. Hamblin, Thomas J. Webster

School of Dentistry Faculty Research and Publications

Currently, Alzheimer's disease (AD) accounts for more than half of all dementia cases. Although genetics, age, and environmental factors affect the disease, the cause of AD is not yet fully known. Various drugs have been proposed for the prevention and treatment of AD, but the delivery of these therapeutic agents to the brain is difficult. The blood–brain barrier prevents systemic drugs from accessing the central nervous system and designing a suitable system to overcome this barrier has attracted much attention. The intranasal pathway, given its proximity to the brain, provides a great opportunity for drug delivery. Understanding the physiological characteristics …


Does Supplemental Regional Anesthesia Decrease Length Of Stay And Opioid Use For Patients Undergoing Head And Neck Microvascular Reconstruction?, Earl Peter Park, John Minh Le, Jordan Gigliotti, Joel Feinstein, Yedeh P. Ying, Anthony B. Morlandt 2021 LSU Health Sciences Center - New Orleans

Does Supplemental Regional Anesthesia Decrease Length Of Stay And Opioid Use For Patients Undergoing Head And Neck Microvascular Reconstruction?, Earl Peter Park, John Minh Le, Jordan Gigliotti, Joel Feinstein, Yedeh P. Ying, Anthony B. Morlandt

School of Dentistry Faculty Publications

Purpose: The purpose of this study was to compare length of hospital stay and opioid usage among head and neck surgery (HNS) patients treated with and without regional anesthesia for microvascular free-flap donor sites. Methods: The authors performed a retrospective cohort study for HNS patients undergoing microvascular free-flap reconstruction. The control group received no regional anesthesia. The experimental group had a regional anesthesia nerve block performed immediately before surgery. The primary outcome variable was length of stay, and the secondary outcome variable was total morphine milliequivalents. The data were analyzed using Student t tests, analysis of variance, Mann-Whitney U test, …


Characterization Of Dental Pulp Stem Cell Responses To Functional Biomaterials Including Mineralized Trioxide Aggregates, Sejin Bae, Bueonguk Kang, Hyungbin Lee, Harrison Luu, Eric Mullins, Karl Kingsley 2021 University of Nevada, Las Vegas

Characterization Of Dental Pulp Stem Cell Responses To Functional Biomaterials Including Mineralized Trioxide Aggregates, Sejin Bae, Bueonguk Kang, Hyungbin Lee, Harrison Luu, Eric Mullins, Karl Kingsley

Dental Medicine Faculty Research

Introduction: Many studies in stem cell biology have demonstrated that dental pulp stem cells (DPSC) may be highly proliferative and capable of pluripotent differentiation into many different tissue types. Recent advances in stem cell research have outlined methods for directing in vitro or in vivo growth, viability, and proliferation, as well as differentiation of DPSC-although much remains to be discovered. Based upon this information, the primary objective of this study was to understand the functional biomaterials needed to more effectively direct DPSC viability, growth, and proliferation. Methods: Using an approved protocol, previously collected and isolated samples of DPSC from an …


Overexpression Of Mir-1306-5p, Mir-3195, And Mir-3914 Inhibits Ameloblast Differentiation Through Suppression Of Genes Associated With Human Amelogenesis Imperfecta, Hiroki Yoshioka, Yin-Ying Wang, Akiko Suzuki, Meysam Shayegh, Mona V Gajera, Zhongming Zhao, Junichi Iwata 2021 The Texas Medical Center Library

Overexpression Of Mir-1306-5p, Mir-3195, And Mir-3914 Inhibits Ameloblast Differentiation Through Suppression Of Genes Associated With Human Amelogenesis Imperfecta, Hiroki Yoshioka, Yin-Ying Wang, Akiko Suzuki, Meysam Shayegh, Mona V Gajera, Zhongming Zhao, Junichi Iwata

Faculty, Staff and Student Publications

Amelogenesis imperfecta is a congenital form of enamel hypoplasia. Although a number of genetic mutations have been reported in humans, the regulatory network of these genes remains mostly unclear. To identify signatures of biological pathways in amelogenesis imperfecta, we conducted bioinformatic analyses on genes associated with the condition in humans. Through an extensive search of the main biomedical databases, we found 56 genes in which mutations and/or association/linkage were reported in individuals with amelogenesis imperfecta. These candidate genes were further grouped by function, pathway, protein-protein interaction, and tissue-specific expression patterns using various bioinformatic tools. The bioinformatic analyses highlighted a group …


Oral Health Is Important, But How Important?, Alexander G. Dengel 2021 Syracuse University

Oral Health Is Important, But How Important?, Alexander G. Dengel

Population Health Research Brief Series

Dental care is often overlooked as a priority and sometimes considered more of a chore rather than an important aspect of personal health. This oversight can lead to poor health outcomes like gingivitis, periodontitis, and even chronic illness like heart disease, diabetes, and cancer. This issue brief describes the short- and long-term effects of a poor dental health routine and the simple steps necessary to maintain a healthy smile.


Trident - Spring 2021, Dugoni School of Dentistry 2021 University of the Pacific

Trident - Spring 2021, Dugoni School Of Dentistry

Trident

The newsletter of the Pacific Orthodontic Alumni Chapter at University of the Pacific, Arthur A. Dugoni School of Dentistry. This issue is dedicated to the memory of our late Dean Emeritus Dr. Dugoni.


Total Salivary Protein Concentration And Its Correlation To Dental Caries, Emyli Peralta, Jonathan Joseph 2021 University of Central Florida

Total Salivary Protein Concentration And Its Correlation To Dental Caries, Emyli Peralta, Jonathan Joseph

The Pegasus Review: UCF Undergraduate Research Journal

According to the World Health Organization, dental cavities are the number one chronic disease in children. Saliva coats the teeth all day and serves many functions to maintain and protect teeth. Saliva has many proteins that can be both detrimental and essential to the preservation of tooth enamel. The purpose of this study was to determine if a correlation exists between the total protein concentration in saliva and the prevalence of cavities in the mouth. We hypothesized that there would be a positive correlation between total salivary protein concentration and the prevalence of cavities in the participant.Saliva samples were collected …


The Potential Of Raman Spectroscopy In The Diagnosis Of Dysplastic And Malignant Oral Lesions, Ola Ibrahim, M. Toner, Steven Flint, Hugh Byrne, Fiona Lyng 2021 Technological University Dublin

The Potential Of Raman Spectroscopy In The Diagnosis Of Dysplastic And Malignant Oral Lesions, Ola Ibrahim, M. Toner, Steven Flint, Hugh Byrne, Fiona Lyng

Articles

Early diagnosis, treatment and/or surveillance of oral premalignant lesions are important in preventing progression to oral squamous cell carcinoma (OSCC). The current gold standard is through histopathological diagnosis, which is limited by inter and intra observer and sampling errors. The objective of this work was to use Raman spectroscopy to discriminate between benign, mild, moderate and severe dysplasia and OSCC in formalin fixed paraffin preserved (FFPP) tissues. The study included 72 different pathologies from which 17 were benign lesions, 20 mildly dysplastic, 20 moderately dysplastic, 10 severely dysplastic and 5 invasive OSCC. The glass substrate and paraffin wax background were …


Phenytoin Inhibits Cell Proliferation Through Microrna-196a-5p In Mouse Lip Mesenchymal Cells, Hiroki Yoshioka, Sai Shankar Ramakrishnan, Akiko Suzuki, Junichi Iwata 2021 The Texas Medical Center Library

Phenytoin Inhibits Cell Proliferation Through Microrna-196a-5p In Mouse Lip Mesenchymal Cells, Hiroki Yoshioka, Sai Shankar Ramakrishnan, Akiko Suzuki, Junichi Iwata

Faculty, Staff and Student Publications

Cleft lip (CL) is one of the most common birth defects. It is caused by either genetic mutations or environmental factors. Recent studies suggest that environmental factors influence the expression of noncoding RNAs [e.g., microRNA (miRNA)], which can regulate the expression of genes crucial for cellular functions. In this study, we examined which miRNAs are associated with CL. Among 10 candidate miRNAs (miR-98-3p, miR-101a-3p, miR-101b-3p, miR-141-3p, miR-144-3p, miR-181a-5p, miR-196a-5p, miR-196b-5p, miR-200a-3p, and miR-710) identified through our bioinformatic analysis of CL-associated genes, overexpression of miR-181a-5p, miR-196a-5p, miR-196b-5p, and miR-710 inhibited cell proliferation through suppression of genes associated with CL in cultured …


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