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Research Methods in Life Sciences Commons

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1,137 full-text articles. Page 6 of 41.

The Neurological Asymmetry Of Self-Face Recognition, Aleksandra Janowska, Brianna Balugas, Matthew Pardillo, Victoria Mistretta, Katherine Chavarria, Janet Brenya, Taylor Shelansky, Vanessa Martinez, Kitty Pagano, Nathira Ahmad, Samantha Zorns, Abigail Straus, Sarah Sierra, Julian Keenan 2021 Montclair State University

The Neurological Asymmetry Of Self-Face Recognition, Aleksandra Janowska, Brianna Balugas, Matthew Pardillo, Victoria Mistretta, Katherine Chavarria, Janet Brenya, Taylor Shelansky, Vanessa Martinez, Kitty Pagano, Nathira Ahmad, Samantha Zorns, Abigail Straus, Sarah Sierra, Julian Keenan

Department of Biology Faculty Scholarship and Creative Works

While the desire to uncover the neural correlates of consciousness has taken numerous directions, self-face recognition has been a constant in attempts to isolate aspects of self-awareness. The neuroimaging revolution of the 1990s brought about systematic attempts to isolate the underlying neural basis of self-face recognition. These studies, including some of the first fMRI (functional magnetic resonance imaging) examinations, revealed a right-hemisphere bias for self-face recognition in a diverse set of regions including the insula, the dorsal frontal lobe, the temporal parietal junction, and the medial temporal cortex. In this systematic review, we provide confirmation of these data (which are …


Science Forum: A Community-Led Initiative For Training In Reproducible Research, Susann Auer, Nele A. Haeltermann, Tracey L. Weissberger, Jeffrey C. Erlich, Damar Susilaradeya, Magdalena Julkowska, Małgorzata Anna Gazda, Benjamin Schwessinger, Nafisa M. Jadavji, Angela Abitua, Anzela Niraulu, Aparna Shah, April Clyburne-Sherinb, Benoit Guiquel, Bradly Alicea, Caroline LaManna, Diep Ganguly, Eric Perkins, Helena Jambor, Ian Man Ho Li, Jennifer Tsang, Joanne Kamens, Lenny Teytelman, Mariella Paul, Michelle Cronin, Nicolas Schmelling, Peter Crisp, Rintu Kutum, Santosh Phuyal, Sarvenaz Sarabipour, Sonali Roy, Susanna M. Bachle, Tuan Tran, Tyler Ford, Vicky Steeves, Vinodh Ilangovan, Ana Baburamani 2021 Technische Universität Dresden

Science Forum: A Community-Led Initiative For Training In Reproducible Research, Susann Auer, Nele A. Haeltermann, Tracey L. Weissberger, Jeffrey C. Erlich, Damar Susilaradeya, Magdalena Julkowska, Małgorzata Anna Gazda, Benjamin Schwessinger, Nafisa M. Jadavji, Angela Abitua, Anzela Niraulu, Aparna Shah, April Clyburne-Sherinb, Benoit Guiquel, Bradly Alicea, Caroline Lamanna, Diep Ganguly, Eric Perkins, Helena Jambor, Ian Man Ho Li, Jennifer Tsang, Joanne Kamens, Lenny Teytelman, Mariella Paul, Michelle Cronin, Nicolas Schmelling, Peter Crisp, Rintu Kutum, Santosh Phuyal, Sarvenaz Sarabipour, Sonali Roy, Susanna M. Bachle, Tuan Tran, Tyler Ford, Vicky Steeves, Vinodh Ilangovan, Ana Baburamani

Agricultural and Environmental Sciences Faculty Research

Open and reproducible research practices increase the reusability and impact of scientific research. The reproducibility of research results is influenced by many factors, most of which can be addressed by improved education and training. Here we describe how workshops developed by the Reproducibility for Everyone (R4E) initiative can be customized to provide researchers at all career stages and across most disciplines with education and training in reproducible research practices. The R4E initiative, which is led by volunteers, has reached more than 3000 researchers worldwide to date, and all workshop materials, including accompanying resources, are available under a CC-BY 4.0 license …


A Qualitative Study On The Factors Affecting The Willingness Of 3rd Level Students To Register As Organ Donors In Ireland, Evelyn Hayes, Erika Horan, Cian Lally, Aisling Murphy 2021 Munster Technological University

A Qualitative Study On The Factors Affecting The Willingness Of 3rd Level Students To Register As Organ Donors In Ireland, Evelyn Hayes, Erika Horan, Cian Lally, Aisling Murphy

International Undergraduate Journal of Health Sciences

A wide range of factors contribute to an individual’s choice whether or not to register as an organ donor. The knowledge of the Irish population at large around the area of donation and transplantation is varied. A research survey was designed to be completed by third level students. The purpose of the research was to determine the most important factors that played a role in their decisions regarding opting-in to organ donation. A second aim of the survey was to determine the participants’ levels of knowledge and understanding on the ‘opt in’ donation system in place here in Ireland.

The …


Full Issue: The International Undergraduate Journal Of Health Sciences, Volume 1, Issue 1, June 2021, 2021 Munster Technological University

Full Issue: The International Undergraduate Journal Of Health Sciences, Volume 1, Issue 1, June 2021

International Undergraduate Journal of Health Sciences

The full June 2021 issue (Volume 1, Issue 1) of the International Undergraduate Journal of Health Sciences


Non-Reductionist Science: Assessing Metabolism And Entropy With Systems Theory And Hegelian Logic, Tre Schumacher 2021 Tre Schumacher

Non-Reductionist Science: Assessing Metabolism And Entropy With Systems Theory And Hegelian Logic, Tre Schumacher

Undergraduate Research

This paper will offer Hegelian logic, its connection with systems theory, and how it can serve as a replacement for reductionism in the sciences. First, the connection will be made between formal logic and reductionism. Second, systems theory will be introduced as an alternative to reductionism. Third, Hegelian logic and its connection with systems theory will be demonstrated. Fourth, a non-reductionist mode of science will be offered, wherein Hegelian logic and systems theory can work alone or together, in replacement of reductionism and formal logic. Last, a brief sample of this mode of science will be shown in an examination …


Biodiversity Monitoring And Volunteer Motivations: A Case Study On The Imagined Communities Of Citizen Scientists In Meinung, Taiwan, Serena May Calcagno 2021 University of San Francisco

Biodiversity Monitoring And Volunteer Motivations: A Case Study On The Imagined Communities Of Citizen Scientists In Meinung, Taiwan, Serena May Calcagno

Master's Projects and Capstones

The Asia Pacific’s biodiversity is under threat. One significant step that can improve conservation is gathering data on what species exist in different areas over time, which can provide insight into ecosystem health. This is especially important in biodiversity hotspots, where high levels of endemism and anthropogenic risk overlap. Though it is one of the few places in the Pacific not classified as a biodiversity hotspot, Taiwan has an unusually high saturation in terms of biodiversity data points. Investigating the motives of biodiversity monitoring volunteerism is already a topic of growing scholarly interest, but relatively few studies have focused on …


Larval Chondrocranial And Internal Oral Morphology Of The Neotropical Treefrog Boana Crepitans (Wied-Neuwied, 1824; Amphibia, Anura, Hylidae), Marianna Isabella Rosa Rodrigues de Oliveira, Luiz Norberto Weber, Johnny Sousa Ferreira, Anna Evelin Coimbra Liborio, André Masahide Guimaraes Takazone, Rafael O. de Sá 2021 University of Richmond

Larval Chondrocranial And Internal Oral Morphology Of The Neotropical Treefrog Boana Crepitans (Wied-Neuwied, 1824; Amphibia, Anura, Hylidae), Marianna Isabella Rosa Rodrigues De Oliveira, Luiz Norberto Weber, Johnny Sousa Ferreira, Anna Evelin Coimbra Liborio, André Masahide Guimaraes Takazone, Rafael O. De Sá

Biology Faculty Publications

We describe the internal oral morphology and chondrocranial anatomy for Boana crepitans tadpoles, and compare them with available descriptions for other species in the subfamily Cophomantinae. Among species of the Boana faber group, the chondrocranial anatomy has been reported only for one species internal oral morphology and cranial anatomy are similar to other described species of Boana and Cophomantinae. B. crepitans lacks unique features in the oral cavity and chondrocranium that would distinguish it from other congeneric species. We identify six characters from the internal oral anatomy of tadpoles unique for Cophomantinae. In addition, Boana has infralabial papillae projections, buccal …


Mapping The Little Brain At The Heart By An Interdisciplinary Systems Biology Team., Rajanikanth Vadigepalli, James S. Schwaber 2021 Daniel Baugh Institute for Functional Genomics/Computational Biology, Department of Pathology, Thomas Jefferson University, Philadelphia, PA 19107, USA

Mapping The Little Brain At The Heart By An Interdisciplinary Systems Biology Team., Rajanikanth Vadigepalli, James S. Schwaber

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

No abstract provided.


Cnd-1/Neurod Is Required For Rme Head Neuron Cell Fate Specification In The Nematode Caenorhabditis Elegans., Genevieve Doxakis 2021 Kennesaw State University

Cnd-1/Neurod Is Required For Rme Head Neuron Cell Fate Specification In The Nematode Caenorhabditis Elegans., Genevieve Doxakis

Symposium of Student Scholars

cnd-1/NeuroD is required for RME head neuron cell fate specification in the nematode Caenorhabditis elegans.

Genevieve Doxakis (1), Illyana Weitzel (2), Amber Baldwin (1), Davron Hanley (1), and Martin L. Hudson (1)

(1) Department of Molecular and Cellular Biology, Kennesaw State University

(2) STEM Magnet Program, Wheeler High School

Transcription factors are proteins that control gene transcription. NeuroD is a deeply conserved transcription factor that regulates neuronal differentiation and pancreatic development. Mutations in this gene correlate with several neurological disorders, creating an imperative for further study. The nematode Caenorhabditis elegans has a NeuroD ortholog, cnd-1, which means we can use …


The Effects Of Mapk Signaling On The Development Of Cerebellar Granule Cells, Kerry Morgan 2021 University of Connecticut

The Effects Of Mapk Signaling On The Development Of Cerebellar Granule Cells, Kerry Morgan

University Scholar Projects

The granule cells are the most abundant neuronal type in the human brain. Rapid proliferation of granule cell progenitors results in dramatic expansion and folding of the cerebellar cortex during postnatal development. Mis-regulation of this proliferation process causes medulloblastoma, the most prevalent childhood brain tumor. In the developing cerebellum, granule cells are derived from Atoh1-expressing cells, which arise from the upper rhombic lip (the interface between the roof plate and neuroepithelium). In addition to granule cells, the Atoh1 lineage also gives rise to different types of neurons including cerebellar nuclei neurons. In the current study, I have investigated the …


The Effects Of Mapk Signaling On The Development Of Cerebellar Granule Cells, Kerry Morgan 2021 University of Connecticut

The Effects Of Mapk Signaling On The Development Of Cerebellar Granule Cells, Kerry Morgan

Honors Scholar Theses

The granule cells are the most abundant neuronal type in the human brain. Rapid proliferation of granule cell progenitors results in dramatic expansion and folding of the cerebellar cortex during postnatal development. Mis-regulation of this proliferation process causes medulloblastoma, the most prevalent childhood brain tumor. In the developing cerebellum, granule cells are derived from Atoh1-expressing cells, which arise from the upper rhombic lip (the interface between the roof plate and neuroepithelium). In addition to granule cells, the Atoh1 lineage also gives rise to different types of neurons including cerebellar nuclei neurons. In the current study, I have investigated the …


Safety Of Silver Oxide Coated Biomaterials In Mice, Michael Klug, Darien L. Seidman, Rahyan Mahmoud, Destiny Morot, Lei Yu, Jeffrey D Hettinger, Renee M Demarest 2021 Rowan University

Safety Of Silver Oxide Coated Biomaterials In Mice, Michael Klug, Darien L. Seidman, Rahyan Mahmoud, Destiny Morot, Lei Yu, Jeffrey D Hettinger, Renee M Demarest

Stratford Campus Research Day

It has been demonstrated that silver oxide coatings designed by our collaborators are able to prevent E. coli and P. aeruginosa attachment to biomaterials in vivo. These findings demonstrate that such coatings show promise in preventing the development of biofilm on biodevices. However, it is unknown if the use of silver oxide in this fashion is toxic in vivo. The goal of this project was to determine whether our silver oxide coatings are safe to use in vivo. To assess the toxicity of our silver oxide formula, mice were implanted with either silver oxide coated titanium discs or uncoated titanium …


Evaluation Of A Keratin 1 Targeting Peptide-Doxorubicin Conjugate In A Mouse Model Of Triple-Negative Breast Cancer, Azam Saghaeidehkordi, Shiuan Chen, Sun Yang, Kamaljit Kaur 2021 Chapman University

Evaluation Of A Keratin 1 Targeting Peptide-Doxorubicin Conjugate In A Mouse Model Of Triple-Negative Breast Cancer, Azam Saghaeidehkordi, Shiuan Chen, Sun Yang, Kamaljit Kaur

Pharmacy Faculty Articles and Research

Chemotherapy is the main treatment for triple-negative breast cancer (TNBC), a subtype of breast cancer that is aggressive with a poor prognosis. While chemotherapeutics are potent, these agents lack specificity and are equally toxic to cancer and nonmalignant cells and tissues. Targeted therapies for TNBC treatment could lead to more safe and efficacious drugs. We previously engineered a breast cancer cell targeting peptide 18-4 that specifically binds cell surface receptor keratin 1 (K1) on breast cancer cells. A conjugate of peptide 18-4 and doxorubicin (Dox) containing an acid-sensitive hydrazone linker showed specific toxicity toward TNBC cells. Here, we report the …


Role Of Reptile-Invertebrate Interactions In Enigmatic Reptile Declines, Meredith Swartwout 2021 University of Arkansas, Fayetteville

Role Of Reptile-Invertebrate Interactions In Enigmatic Reptile Declines, Meredith Swartwout

Graduate Theses and Dissertations

Reptile populations are declining world-wide and the mechanisms behind many of these declines remain enigmatic. Food web interactions (i.e., reduced prey availability or increased predation) have been implicated behind some reptile declines. However, relatively little is known about predation on lizard and snake eggs, despite egg survival being important for population dynamics of some species. Ants are important predators of squamate reptile eggs in tropical and temperate systems. In Costa Rica, long-term declines in terrestrial anole lizards were linked with reduced leaf litter depth, a factor that could influence egg vulnerability to ant predation. Fire ants (genus Solenopsis) are aggressive …


Psychedelics Can Save: The Scientific And Social Case For Rescheduling Psychedelic Compounds, Galen M. Fader 2021 University of Tennessee, Knoxville

Psychedelics Can Save: The Scientific And Social Case For Rescheduling Psychedelic Compounds, Galen M. Fader

Chancellor’s Honors Program Projects

No abstract provided.


Unraveling Host-Gut Microbiota Dialogue And Its Impact On Response To Immune Checkpoint Blockade, Alexandria Cogdill 2021 The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences

Unraveling Host-Gut Microbiota Dialogue And Its Impact On Response To Immune Checkpoint Blockade, Alexandria Cogdill

The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences Dissertations and Theses (Open Access)

Cancer is a disease with only one degree of separation, affecting one in two men and one in three women in their lifetimes; accounting for 1 of every 6 deaths. While cancer mortality rates continue to improve, incidence rates are expected to rise and shift through 2050 due to epidemiological and demographic transitions worldwide. As such, it is imperative to continue to investigate and improve our understanding of both disease etiology and hallmarks of response to treatment. Currently, conventional therapies include, but are not limited to, surgery, chemotherapy, and radiotherapy. However, within the past decade, major advances have been made …


Survey Of Ticks And Tick-Borne Pathogens Associated With Feral Swine (Sus Scrofa) In Arkansas, Haylee Campbell 2021 University of Arkansas, Fayetteville

Survey Of Ticks And Tick-Borne Pathogens Associated With Feral Swine (Sus Scrofa) In Arkansas, Haylee Campbell

Graduate Theses and Dissertations

Feral hogs (Sus scrofa L.) are an invasive species throughout the southeast United States and found in every Arkansas county. As feral hogs invade new habitat, they can disrupt ecosystems, damage agriculture systems, and bring ticks and tick-borne pathogens with them. There are no surveys of the tick species parasitizing the Arkansas feral hog populations or the pathogens they carry. This is a public health concern because feral hogs occupy often same geographical regions as humans and livestock and can harbor over 45 animal diseases and parasites. The ticks carried by feral hogs can carry tick-borne pathogens that can cause …


Climate-Driven Impacts On Himalayan Aquatic Biodiversity: A Case Study Involving Snowtrout (Cyprinidae: Schizothorax), Riri Wiyanti Retnaningtyas 2021 University of Arkansas, Fayetteville

Climate-Driven Impacts On Himalayan Aquatic Biodiversity: A Case Study Involving Snowtrout (Cyprinidae: Schizothorax), Riri Wiyanti Retnaningtyas

Graduate Theses and Dissertations

Monitoring biodiversity, to include its relative dispersal and contraction, has become a conservation task of great importance, particularly given the catastrophic and ongoing loss of habitat due to climate change. However, the timing, direction, and magnitude of these rates vary across taxa and ecosystems. Predicting specific impacts of climate change can thus be difficult and this, in turn, hampers management action. Metrics are needed to not only quantify contemporary requirements of species, but also predict potential distributions that fluctuate in lockstep with climate.

Montane ecosystems in the Himalayas are highly impacted by climate change, yet remain largely understudied due to …


Pathogenesis Of Dry Eye In Graft Versus Host Disease (Gvhd): Role Of Ocular Mucins And Conjunctival Fibrosis, Kiumars Shamloo 2021 Chapman University

Pathogenesis Of Dry Eye In Graft Versus Host Disease (Gvhd): Role Of Ocular Mucins And Conjunctival Fibrosis, Kiumars Shamloo

Pharmaceutical Sciences (PhD) Dissertations

Allogenic hematopoietic stem cell transplantation is a procedure that offers a possible cure for hematologic cancers and other hematologic disorders. Unfortunately, despite the increasing survival rate of patients, the quality of their life is adversely affected by the allogeneic bone marrow transplantation’s major side effect i.e Graft vs. Host Disease (GVHD). GVHD is a complex, multi-organ disease resulting from an immunological attack by donor engrafted immune cells to host organs, including the eye surface. Mostly based on the time of disease onset after transplantation, GVHD is divided into the acute and chronic phase. The eyes may be involved in both …


Evaluation Of Weight Gain, Feed Intake, Feed Conversion And Oocyst Shedding Of Eimeria Maxima And Eimeria Acervulina In Broiler Chickens, Lauren Laverty 2021 University of Arkansas, Fayetteville

Evaluation Of Weight Gain, Feed Intake, Feed Conversion And Oocyst Shedding Of Eimeria Maxima And Eimeria Acervulina In Broiler Chickens, Lauren Laverty

Poultry Science Undergraduate Honors Theses

The purpose of the present study was to evaluate the day and the time of sample collection of an

experimental challenge with Eimeria maxima (EM) and Eimeria acervulina (EA) in broiler chickens. One day old male Cobb-Vantress broiler chickens were randomly allocated to one of three groups with ten replicates (n=8 chickens/replicate). Chickens were placed in battery cages with a controlled age-appropriate environment: Group 1) Negative control (no challenge or treatment); 2) Challenge control (Eimeria challenge only); 3) Challenge + Salinomycin. Challenged chickens were orally gavaged with the mixed culture of EM/EA (10,000 sporulated EM containing 4% wild-type EA) …


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