Stability Evaluation Of A Hair Conditioner Comprising A Mixed Extract From Fruits Of Phyllanthus Emblica And Zanthoxylum Limon Ella,
2013
Chulalongkorn University
Stability Evaluation Of A Hair Conditioner Comprising A Mixed Extract From Fruits Of Phyllanthus Emblica And Zanthoxylum Limon Ella, Sitthiphong Soradech, Buppachart Potduang, Itsara Keeta, Wanlapha Saisin, Suchipha Wannaphatchaiyong, Cholticha Niwaspragrit
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Pharmacokinetic And Bioequivalence Evaluation Of Two Formulations Of Levocetirizine 5 Mg In Healthy Thai Volunteers,
2013
Chulalongkorn University
Pharmacokinetic And Bioequivalence Evaluation Of Two Formulations Of Levocetirizine 5 Mg In Healthy Thai Volunteers, Chutima Jantarat, Thitima Keskanokwong
The Thai Journal of Pharmaceutical Sciences
Pharmacokinetics of levoceterizine have been studied, however, obtained information was only from the Western people. เท addition, the license of this drug formulation was expired few years ago. For approval of this new generic drug, the bioequivalen...
Compulsory Licensing Of Chronic Diseases Pharmaceuticals Thailand,
2013
Chulalongkorn University
Compulsory Licensing Of Chronic Diseases Pharmaceuticals Thailand, Sakda Thanicul, Matthew Lim Braslow
The Thai Journal of Pharmaceutical Sciences
For pharmaceutical companies, obtaining patent protection for the pharmaceuticals they develop is essential. Patent protection assures that the pharmaceutical company will have a reasonable opportunity to recoup their most likely quite heavy investment in the new drug and allow the company to control the wholesale market price of the drugs. These key intellectual property rights are truly at the heart of the internationally recognized intellectual property regime. For patent right holders in general merchandise, say an innovative paperclip or mousetrap, the absolute right of the patent holder as to the distribution and price is perfectly acceptable. Pharmaceutical patents however, with …
Detection Of Esterase Activity Converting Cytotoxic Renieramycin M To Jorunnamycin A In The Crude Enzyme Of The Nudibranch Jorunna Funebris,
2013
Chulalongkorn University
Detection Of Esterase Activity Converting Cytotoxic Renieramycin M To Jorunnamycin A In The Crude Enzyme Of The Nudibranch Jorunna Funebris, Dalad Waropastrakul., Khanit Suwanborirux, Wanchai De-Eknamkul, Taksina Chuanasa
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Use Of Three Thai Indigenous Vegetables As Potential Dietary Fiber Sources For Health Food Product,
2013
Chulalongkorn University
Use Of Three Thai Indigenous Vegetables As Potential Dietary Fiber Sources For Health Food Product, Jeeravu Thongdon-A., Prapaipat Klungsupya, Thanchanok Muangman, Arkachai Tantrawong, Srisak Trangvacharakul
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Solubility And Dissolution Enhancement Of Quercetin Via Preparation Of Spray Dried Microstructured Solid Dispersions,
2013
Chulalongkorn University
Solubility And Dissolution Enhancement Of Quercetin Via Preparation Of Spray Dried Microstructured Solid Dispersions, Ahmed Shawky Mohamed Ghanem, Hany Saleh, Sohair Mostafa El-Shanawany, El-Sayed Ali Ibrahim
The Thai Journal of Pharmaceutical Sciences
Quercetin (QC) is a bioflavonoid characterized with poor water solubility that limits its oral bioavailability and hence its therapeutic applications. เท an attempt to enhance its solubility and dissolution rate, both binary and ternary microstructur...
Bioequivalence Study Of 300 Mg Irbesartan Film-Coated Tablets Preparations In Healthy Thai Volunteers,
2013
Chulalongkorn University
Bioequivalence Study Of 300 Mg Irbesartan Film-Coated Tablets Preparations In Healthy Thai Volunteers, Porranee Puranajoti, Peerawong Werarak, Burapat Intawong, Jarunee Hongrapipat, Rungrudee Talubsri, Soravee Sangsuriyawong, Temsiri Kuamsuk
The Thai Journal of Pharmaceutical Sciences
Irbesartan, an angiotensin II receptor antagonist, is indicated for the treatment of essential hypertension alone or in combination with other antihypertensive agents. The purpose of this study was to compare the bioavailability of two formulations of ir...
Quantitative Analysis Of Epigallocatechin Gallate In Young And Mature Assam Tea Leaf Extracts,
2013
Chulalongkorn University
Quantitative Analysis Of Epigallocatechin Gallate In Young And Mature Assam Tea Leaf Extracts, Pattra Ahmadi Pirshahid, Thongchai Hemthanon, Yaowaluk Khamphan, Phatsuda Chueboonmee, Chuleratana Banchonglikitkul
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Pilot Study Of Antibacterial And Antiinflammatory Activities Of Indian Gooseberry (Phyllanthus Emblica L. Extract) Against Bacteria Associated With Pitted Keratolysis,
2013
Chulalongkorn University
Pilot Study Of Antibacterial And Antiinflammatory Activities Of Indian Gooseberry (Phyllanthus Emblica L. Extract) Against Bacteria Associated With Pitted Keratolysis, Rattanasiri Giwanon., Krittiva Thisayakom, Pongsatom Limsiriwong, Saowaluck Ruengsri, Vichein Kheuynok, Kanchana Sriyam, Marudech Srisom, Darunee Pahusee, Sawai Nakakaew, Natthachest Ketmanee, Sontaya Peungsumrong, Chulerattana Banchonglikitkul
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Radical-Scavenging And Cellular Dna Protective Activities Of Active Fractions From Lansivm Domesticum Corr. Fruit,
2013
Chulalongkorn University
Radical-Scavenging And Cellular Dna Protective Activities Of Active Fractions From Lansivm Domesticum Corr. Fruit, Prapaipat Klungsupya, Nava Suthepakul, Sarunya Laovitthayanggoon, Jeerayu Thongdon-A, Srisak Trangwacharakul
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Cytotoxic Evaluation Of A Fruit Extract From Zanthoxylum Limonella In Human Dermal Fibroblast Cell Line Using Mtt Assay,
2013
Chulalongkorn University
Cytotoxic Evaluation Of A Fruit Extract From Zanthoxylum Limonella In Human Dermal Fibroblast Cell Line Using Mtt Assay, Sarunva Laovitthayanggoon., Buppachart Potduang, Natthachest Ketmanee, Chuleratana Banchonglikitkul
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Fabrication Of Meloxicam Taste-Masked Oral Fast Disintegrating Tablet By Ion Exchange Resin And Cyclodextrin,
2013
Chulalongkorn University
Fabrication Of Meloxicam Taste-Masked Oral Fast Disintegrating Tablet By Ion Exchange Resin And Cyclodextrin, Wipada Samprasit, Theerasak Rojanarata, Prasert Akkaramongkolpom, Tanasait Ngawhirunpat, Praneet Opanasopit
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Development Of Garcinia Mangostana Extract In Liquid Crystal Cream For Topical Delivery System,
2013
Chulalongkorn University
Development Of Garcinia Mangostana Extract In Liquid Crystal Cream For Topical Delivery System, Napa Bunma, Jirapan Moungjaroen, Prasan Tanguenyongwatana
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Formulation Of Ketoprofen Matrix Membrane For Transdermal Delivery Systems,
2013
Chulalongkorn University
Formulation Of Ketoprofen Matrix Membrane For Transdermal Delivery Systems, Jirapomehai Suksaeree, Wiwat Pichayakorn, Chaowalit Monton, Apirak Sakunpak, Tun Chusut, Worawan Saingam, Fameera Madaka
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Cosmeceutical Development Of Oxyresveratrol From Mahad (Artocarpus Lakoocha Roxb.),
2013
Chulalongkorn University
Cosmeceutical Development Of Oxyresveratrol From Mahad (Artocarpus Lakoocha Roxb.), Surapol Natakankitkul, Nicha Chareonmuang, Tawan Panyakhong, Worrapon Wangkananon
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Time Kill Study Of The In Vitro Activity Of Tigecycline Against Carbapenem-Resistant Klebsiella Pneumoniae,
2013
Chulalongkorn University
Time Kill Study Of The In Vitro Activity Of Tigecycline Against Carbapenem-Resistant Klebsiella Pneumoniae, Maimun Halee, Wanchai Treyaprasert, Pompan Koomanachai, Duangdao Waywa
The Thai Journal of Pharmaceutical Sciences
No abstract provided.
Study Of Charge-Dependent Transport And Toxicity Of Peptide-Functionalized Silver Nanoparticles Using Zebrafish Embryos And Single Nanoparticle Plasmonic Spectroscopy,
2013
Old Dominion University
Study Of Charge-Dependent Transport And Toxicity Of Peptide-Functionalized Silver Nanoparticles Using Zebrafish Embryos And Single Nanoparticle Plasmonic Spectroscopy, Kerry J. Lee, Lauren M. Browning, Prakash D. Nallathamby, Xiao-Hong Nancy Xu
Chemistry & Biochemistry Faculty Publications
Nanomaterials possess unusually high surface area-to-volume ratios and surface-determined physicochemical properties. It is essential to understand their surface-dependent toxicity in order to rationally design biocompatible nanomaterials for a wide variety of applications. In this study, we have functionalized the surfaces of silver nanoparticles (Ag NPs, 11.7 ±+2.7 nm in diameter) with three biocompatible peptides (CALNNK, CALNNS, CALNNE) to prepare positively (Ag-CALNNK NPs+ζ), negatively (Ag-CALNNS NPs−2ζ), and more negatively charged NPs (Ag-CALNNE NPs−4ζ), respectively. Each peptide differs in a single amino acid at its C-terminus, which minimizes the effects of peptide sequences and serves as …
Acidic Pericellular Ph: Effects On Proteolysis And Gene Expression As Determined In 3d Models Of Breast Carcinoma,
2013
Wayne State University
Acidic Pericellular Ph: Effects On Proteolysis And Gene Expression As Determined In 3d Models Of Breast Carcinoma, Jennifer M. Rothberg
Wayne State University Dissertations
Among the non-cellular microenvironmental factors that contribute to malignancy of solid tumors is an acidic peritumoral pH. The first objective was to determine if an acidic extracellular pH observed in vivo (i.e., pHe 6.8) affects the activity of proteases, such as cathepsin B, that contribute to degradation of collagen IV by tumor cells when grown in biologically relevant three-dimensional cultures. At pHe 6.8 there were increases in pericellular active cysteine cathepsins and in degradation of DQ-collagen IV, which was partially blocked by a cathepsin B inhibitor. Imaging probes for active cysteine cathepsins localized to tumors in vivo. The amount of …
Progress Towards Understanding Of Mechanisms Of Action Of Potent Multifunctional Disease Modifying Therapeutics For Parkinson's Disease & Investigating The Methamphetamine-Induced Striatal Microglia Activation.,
2013
Wayne State University
Progress Towards Understanding Of Mechanisms Of Action Of Potent Multifunctional Disease Modifying Therapeutics For Parkinson's Disease & Investigating The Methamphetamine-Induced Striatal Microglia Activation., Mrudang M. Shah
Wayne State University Dissertations
PROGRESS TOWARDS UNDERSTANDING OF MECHANISMS OF ACTION OF POTENT MULTIFUNCTIONAL DISEASE MODIFYING
THERAPEUTICS FOR PARKINSON'S DISEASE.
by
MRUDANG MANOJKUMAR SHAH
December 2013
Advisor: Dr. Aloke Dutta
Major: Pharmaceutical Sciences
Degree: Doctor of Philosophy
Our long term goal is to design and develop potent multifunctional disease modifying therapeutics for Parkinson's disease. The objective of my dissertation was to understand the mechanisms of action of some potent small molecules (synthesized in our lab) as a disease modifying Parkinson's disease therapeutic. The objective was achieved by pursuing the following two specific aims:
1. Investigating anti-oxidant and neuroprotective effects of a lead molecule (D-512) …
Formulation And Evaluation Of Verapamil Hydrochloride Transmucosal Drug Delivery System,
2013
Chulalongkorn University
Formulation And Evaluation Of Verapamil Hydrochloride Transmucosal Drug Delivery System, Subhash Chandra Bose Penjuri, Saritha Damineni, Nagaraju Ravouru
The Thai Journal of Pharmaceutical Sciences
Verapamil hydrochloride is an antihypertensive agent which undergoes extensive first pass metabolism making it a possible candidate for buccal delivery. Verapamil mucoadhesive buccal patches were prepared using hydroxypropyl methylcellulose, Eudragit RL ...
