A New Rp-Hplc Method For Estimation Of Clindamycin And Adapalene In Gel Formulation: Development And Validation Consideration,
2014
Chulalongkorn University
A New Rp-Hplc Method For Estimation Of Clindamycin And Adapalene In Gel Formulation: Development And Validation Consideration, Rohit. H. Khatri, Rashmin. B. Patel, Mrunali R. Patel
The Thai Journal of Pharmaceutical Sciences
This paper describes a validated high-performance liquid chromatographic (HPLC) method for simultaneous estimation of clindamycin (CLI) and adapalene (ADA) in pure powder and gel formulation. The HPLC separation was achieved on a Luna C18 (2) (250 x 4.6 ...
Verification Of Using Saliva As An Alternative To Serum For Topiramate Monitoring,
2014
Chulalongkorn University
Verification Of Using Saliva As An Alternative To Serum For Topiramate Monitoring, Jareerut Kongrit, Yotin Chinvarun, Nuansri Niwattisaiwong, Somsong Lawanprasert
The Thai Journal of Pharmaceutical Sciences
This study aims to verify the correlation between serum and saliva topiramate concentrations in Thai patients with epilepsy. Twenty-six subjects were patients aged 17-56 years old who were under treatment with topiramate. Their blood and saliva samples w...
Authentication Of A Thai Crude Drug "Kot-Chula-Lumpa" Using Gas Chromatography-Mass Spectrometry And Multivariate Data Analysis,
2014
Chulalongkorn University
Authentication Of A Thai Crude Drug "Kot-Chula-Lumpa" Using Gas Chromatography-Mass Spectrometry And Multivariate Data Analysis, Jankana Burana-Osot, Panadda Phattanawasin, Sununta Srisopon, Praveen Kumar Ashok, Baokang Huang, Uthai Sotanaphun
The Thai Journal of Pharmaceutical Sciences
Kot-chula-lumpa is a crude drug of Thai traditional medicine for fever remedy. To authenticate its botanical origin, gas chromatogram of its non-polar constituents was analysed and compared with those of authentic samples by using chemometric tools. Fing...
Association Of Genetic Variants In Ugt1a6 Genes And Non-Genetic Variant With Valproic Acid Doses And Plasma Concentration In Thai Epileptic Patients,
2014
Chulalongkorn University
Association Of Genetic Variants In Ugt1a6 Genes And Non-Genetic Variant With Valproic Acid Doses And Plasma Concentration In Thai Epileptic Patients, Salinthip Aphichartphunkawee, Yotin Chinvarun, Pornpimol Kijsanayotin
The Thai Journal of Pharmaceutical Sciences
The aim of this study was to investigate the association of genetic variants in UGT1A6 19T>G, 541A>G and 552A>C together with non-genetic variant with VPA dose and plasma concentrations in Thai epileptic patients. Eighty four Thai epileptic patients who ...
Dissolution Enhancement Of Dronedarone Hydrochloride By Complexation With Ss-Cd And Hp Ss-Cd: Dissolution And Physicochemical Characterization,
2014
Chulalongkorn University
Dissolution Enhancement Of Dronedarone Hydrochloride By Complexation With Ss-Cd And Hp Ss-Cd: Dissolution And Physicochemical Characterization, Anjan Kumar Mahapatra, Supriya Samoju, Ruchita Kumari Patra, Padala Narasimha Murthy
The Thai Journal of Pharmaceutical Sciences
The study was aimed to improve solubility or dissolution characteristics of dronedarone hydrochloride by preparing its inclusion complexes (ICs) with ß-cyclodextrin (ß-CD) and hydroxypropyl ß-cyclodextrin (HP ß-CD). The phase solubility behavior of d...
Plant Produced Therapies For Ebola Infection,
2014
Chulalongkorn University
Plant Produced Therapies For Ebola Infection, Waranyoo Phoolcharoen, Matthew Paul
The Thai Journal of Pharmaceutical Sciences
Ebola virus (EBOV) causes severe haemorrhagic fever in humans with high fatality rate up to 90 %. There is currently no approved drug or vaccine for human use. and treatment relies almost exclusively co supportive therapy. However, there are several pote...
Bioequivalence Study Of Abacavir 300 Mg Tablets In Healthy Thai Male Volunteers Under Fasting Conditions,
2014
Chulalongkorn University
Bioequivalence Study Of Abacavir 300 Mg Tablets In Healthy Thai Male Volunteers Under Fasting Conditions, Isariya Techatanawat, Chutima Manamuti, Jaturavit Vattanarongkup, Polsak Teerawonganan, Ekawan Yoosakul, Wiwat Supasena, Bancha Chuasuwan, Piengthong Narakorn, Ponanee Puranaoti
The Thai Journal of Pharmaceutical Sciences
Abacavir is an antiretroviral drug that can be prescribed in single dose or in fixed-dose combination formulations to make adherence easier. Due to this advantage, a generic product of abacavir of GPO has been developed with lower price and would be bene...
Stability Indicating Rp-Hplc Method For Estimation Of Bamifylline Hydrochloride In Tablet Formulation: Development And Validation Consideration,
2014
Chulalongkorn University
Stability Indicating Rp-Hplc Method For Estimation Of Bamifylline Hydrochloride In Tablet Formulation: Development And Validation Consideration, Rashmin. B. Patel, Mrunali. R. Patel, Tapan S. Goswami
The Thai Journal of Pharmaceutical Sciences
A simple, specific and robust stability indicating high performance liquid chromatographic (HPLC) method for estimation of bamifylline hydrochloride was developed and validated. Bamifylline hydrochloride was separated and quantitated on Inertsil ODS-3V c...
Relationship Between Methamphetamine Concentrations In Hair Root, Blood And Urine Samples In Postmortem Cases,
2014
Chulalongkorn University
Relationship Between Methamphetamine Concentrations In Hair Root, Blood And Urine Samples In Postmortem Cases, Sirirat Phomhitatorn, Theerin Sinchai, Nantana Thongra-Ar, Somsong Lawanprasert
The Thai Journal of Pharmaceutical Sciences
Urine and blood samples are normally used to determine methamphetamine (MA) level in forensic and clinical toxicology for assessment of illicit MA use. In cases in which both samples are unavailable or contaminated, hair root has been proposed as an alte...
Antinociceptive And Anti-Inflammatory Activities Of Tree-Phon-Thad Remedy,
2014
Chulalongkorn University
Antinociceptive And Anti-Inflammatory Activities Of Tree-Phon-Thad Remedy, Sunisa Deeoun, Pravaree Phuneerub, Chanida Palanuvej, Nijsiri Ruangrungsi, Pasarapa Towiwat
The Thai Journal of Pharmaceutical Sciences
Tree-Phon-Thad remedy is used as an antipyretic and anti-inflammatory agent by traditional practitioners in Thailand, and includes roots of Zingiber zerumbet (Kra-Thue), Zingiber montamum (Plai) and Cymbopogon nadus (Ta-Krai-Hom). In this study, the anti...
Acute Effects Of Hot Red Chili On Autonomic And Metabolic Functions In Healthy Subjects,
2014
Chulalongkorn University
Acute Effects Of Hot Red Chili On Autonomic And Metabolic Functions In Healthy Subjects, Kannikar Chatsantiprapa, Cameron Hurst, Kaewjai Thepsuthammarat, Nutcharee Thapunkaw, Wilaiwan Khrisanapant
The Thai Journal of Pharmaceutical Sciences
To investigate if chili consumption as a food ingredient in a fried rice meal would have any real acute pharmacological effects on autonomic nervous system (ANS) and metabolic system (MS), a randomized, cross-over, intervention trial was conducted in 33 ...
Short-Term Safety And Efficacy Of Fish-Oil Emulsions On The Prevention Of Parenteral Nutrition-Associated Liver Disease In Surgical Neonates: A Randomized Controlled Trial,
2014
Chulalongkorn University
Short-Term Safety And Efficacy Of Fish-Oil Emulsions On The Prevention Of Parenteral Nutrition-Associated Liver Disease In Surgical Neonates: A Randomized Controlled Trial, Jrarat Ariyawangso, Chankit Puttilerpong, Suntaree Ratanachu-Ek, Maitree Anuntkosol
The Thai Journal of Pharmaceutical Sciences
Surgical neonates requiring prolonged parenteral nutrition (PN) are at risk for parenteral nutrition-associated liver disease (PNALD) that contributes to an increase in morbidity and mortality in surgical infants. Current lipid emulsions used with neonat...
Evaluation Of Analgesic Activity Of Hydroalcoholic Extract Of Ipomoea Staphylina,
2014
Chulalongkorn University
Evaluation Of Analgesic Activity Of Hydroalcoholic Extract Of Ipomoea Staphylina, Soumyadeep Ghosh, M Firdous
The Thai Journal of Pharmaceutical Sciences
This study has been attempted to evaluate analgesic property of hydroalcoholic extract of leaves of Ipomoea staphylina. Analgesic activity was evaluated by abdominal writhing, formalin-induced paw licking method and Eddy's hot plate test in mice. The hyd...
Molecular Binding Modes Of Diarylheptanoids From Curcuma Comosa On The Er-Ss Receptor,
2014
Chulalongkorn University
Molecular Binding Modes Of Diarylheptanoids From Curcuma Comosa On The Er-Ss Receptor, Nathjanan Jongkon, Prasan Tangyuenyongwatana
The Thai Journal of Pharmaceutical Sciences
Curcuma comosa Roxb. is a medicinal plant that belongs to the Zingiberaceae family. The plant has been used in traditional Thai medicine for the treatment of postpartum uterine bleeding. The major compounds found in this plant are diarylheptanoids, which...
Development And Evaluation Of Transdermal Patches Of Aceclofenac,
2014
Chulalongkorn University
Development And Evaluation Of Transdermal Patches Of Aceclofenac, Animesh Gairola, Urmi Chaurasia, Anupama Singh, Vikas Anand Saharan
The Thai Journal of Pharmaceutical Sciences
The aim of this study was to develop and evaluate matrix-type transdermal therapeutic system containing aceclofenac with different ratios of hydrophilic polymers (hydroxylpropyl methylcellulose, sodium carboxy methylcellulose) and a hydrophobic polymer (...
Synthesis And Biological Screening Of Some Thienyl And Phenyl Pyrazoline Derivatives As Antimalarial Agent,
2014
Chulalongkorn University
Synthesis And Biological Screening Of Some Thienyl And Phenyl Pyrazoline Derivatives As Antimalarial Agent, Abdu Tuha, Adnan A. Bekhit, Yimer Seid
The Thai Journal of Pharmaceutical Sciences
Malaria is a common parasitic disease of the developing world and drug resistance has hindered their efficient control. Pyrazole derivatives were synthesized using aldol condensation and subsequent cyclization reactions. The compounds were synthesized in...
In Silico Prediction Of Interaction Between Flavonoids Of Propolis Of Honey Bee And Anthrax Protective Antigen,
2014
Chulalongkorn University
In Silico Prediction Of Interaction Between Flavonoids Of Propolis Of Honey Bee And Anthrax Protective Antigen, Shahin Gavanji, Mohsen Doostmohammadi, Behrouz Larki
The Thai Journal of Pharmaceutical Sciences
The aim of this study was to check the interaction between four ligands (Acacetin, Chrysin, Naringenin and Caffeic Acid Phenethyl Ester) and protective antigen. These ligands are the main flavonoids of propolis of honey. Bioinformatics checking was done ...
Wastewater Influent And Effluent Concentrations Of 17 Beta-Estradiol: A Study Of The Influence Of A University Community And The Risk To Environmental Health,
2014
Eastern Illinois University
Wastewater Influent And Effluent Concentrations Of 17 Beta-Estradiol: A Study Of The Influence Of A University Community And The Risk To Environmental Health, Kyle Heffron
Masters Theses
The concentration of 17β-estradiol (E2) was measured through stages of wastewater treatment at a central Illinois wastewater treatment plant (WWTP). E2 concentration was quantified using a competitive enzyme linked immunosorbent assay (ELISA). The concentration of E2 was compared with demographic effects of a university, physical parameters of the wastewater (dissolved oxygen, pH, and temperature) and daily influent and effluent flow rates. Effluent concentrations ranged from 0 to 25.3 ng L-1 with an average discharge of 3.6 ng L-1. E2 concentration was shown to increase at the start of each university semester, however, this trend was not observed …
The Effects Of 1, 3, & 7 Trisubstituted And 8-Cyclopentyl Alkylxanthines On Respiration In Newborn Rats,
2014
Eastern Illinois University
The Effects Of 1, 3, & 7 Trisubstituted And 8-Cyclopentyl Alkylxanthines On Respiration In Newborn Rats, Nathan Creel Davidson
Masters Theses
Methylxanthines have been shown to be promising respiratory stimulants in newborns suffering from recurrent apnea. The respiratory stimulant effects of methylxanthines are most likely due to their antagonism of adenosine receptors. These drugs have been shown to stimulate respiration in newborn rats in doses in excess of 10 mg/kg body weight. Structure-activity studies have shown that methylxanthines not only differ in the antagonism of A1 and A2 adenosine receptors but also, as a consequence of their different chemical structures, differ in potency as respiratory stimulants. To assess this, two potent A1 adenosine receptor antagonists, 8-cyclopentyl-1,3-dipropylxanthine (DPCPX) and …
Effects Of Anti-Inflammatory Foods On Hyperglycemia In Type-1 Diabetics,
2014
University of Nevada, Las Vegas
Effects Of Anti-Inflammatory Foods On Hyperglycemia In Type-1 Diabetics, Primrose Martin, Michelle Chino
McNair Poster Presentations
Based on a case study administered by Dr. Charlotte Gerson, an IDDM patient referred to as R.H. reversed hyperglycemic symptoms within ten weeks while adhering to a diet of mainly vegetables and some low-glycemic index fruits. R.H. also ingested mineral supplements and underwent multiple coffee enemas each day (Gerson & Bishop, 2007, p. 56). This self-study hypothesizes that diet alone has a positive correlation coefficient with hyperglycemic blood glucose levels in type-1 diabetics (IDDM). Conducting this self-study contributes information to the limited research and database of alternative methods for managing IDDM hyperglycemia, and provides candid documentation of the effects that …
