Biodiversity, Fall/Winter 2012, Issue 25,
2019
University of Louisville
Active Transportation, Spring/Summer 2012, Issue 26,
2019
University of Louisville
Active Transportation, Spring/Summer 2012, Issue 26
Sustain Magazine
No abstract provided.
Heat Islands, Fall/Winter 2014, Issue 29,
2019
University of Louisville
Sustainable Behavior, Spring/Summer 2013, Issue 28,
2019
University of Louisville
Sustainable Behavior, Spring/Summer 2013, Issue 28
Sustain Magazine
No abstract provided.
Local Foods, Fall/Winter 2013, Issue 27,
2019
University of Louisville
Campus Sustainability, Spring/Summer 2014, Issue 30,
2019
University of Louisville
Campus Sustainability, Spring/Summer 2014, Issue 30
Sustain Magazine
No abstract provided.
Zero Waste, Spring/Summer 2017, Issue 36,
2019
University of Louisville
Consent Decrees, Fall/Winter 2017, Issue 35,
2019
University of Louisville
Human Ecology, Spring/Summer 2016, Issue 34,
2019
University of Louisville
Citizen Science, Fall/Winter 2016, Issue 33,
2019
University of Louisville
Urban Streams, Spring/Summer 2015, Issue 32,
2019
University of Louisville
Unconventional Energy, Fall/Winter 2015, Issue 31,
2019
University of Louisville
Unconventional Energy, Fall/Winter 2015, Issue 31
Sustain Magazine
No abstract provided.
Carbon Neutral, Spring/Summer 2018, Issue 38,
2019
University of Louisville
Political Will, Fall/Winter 2018, Issue 37,
2019
University of Louisville
Developing A Dissociative Nanocontainer For Peptide Drug Delivery,
2019
CUNY Graduate Center
Developing A Dissociative Nanocontainer For Peptide Drug Delivery, Michael Patrick Kelly
Dissertations, Theses, and Capstone Projects
The potency and specificity of bioactive peptides have propelled these agents to the forefront of pharmacological research. However, delivery of peptides to their molecular target in cells is a major obstacle to their widespread application. A Trojan Horse strategy of packaging a bioactive peptide within a modified protein cage to protect it during transport, and releasing it at the target site, is a promising delivery method. Recent work has demonstrated that the viral capsid of the P22 bacteriophage can be loaded with an arbitrary, genetically-encoded peptide, and externally decorated with a cell-penetrating peptide, such as HIV-Tat, to translocate across in …
Our Envirome, Spring/Summer 2019, Issue 40,
2019
University of Louisville
Plastic Pollution, Fall/Winter 2019, Issue 39.3,
2019
University of Louisville
Plastic Pollution, Fall/Winter 2019, Issue 39.3
Sustain Magazine
No abstract provided.
Plastic Pollution, Fall/Winter 2019, Issue 39.2,
2019
University of Louisville
Plastic Pollution, Fall/Winter 2019, Issue 39.2
Sustain Magazine
No abstract provided.
Plastic Pollution, Fall/Winter 2019, Issue 39,
2019
University of Louisville
To Compare Cyclosporine A Nanoformulations For Their Effectiveness In Reducing Nephrotoxicity,
2019
University of South Florida
To Compare Cyclosporine A Nanoformulations For Their Effectiveness In Reducing Nephrotoxicity, Ilkin Nasirli
USF Tampa Graduate Theses and Dissertations
Cyclosporine (CsA) is one of the main immune-suppressant agents which has been used widely in organ transplantation against graft rejection. However, the low oral bioavailability and the associated adverse effects such as nephrotoxicity are the main drawbacks of current usage of this drug. Thus, purpose of this research is to formulate PLGA nanoparticles of CsA to improve its effectiveness and to reduce the nephrotoxicity induced by the plain drug. CsA-loaded PLGA nanoparticles were prepared by the nanoprecipitation method. Particle size and zeta potential of the formulation was determined and percent drug entrapment were also determined. Quantitative estimation was carried out …
