The Analytical And Biomedical Applications Of Carbon Dots And Their Future Theranostic Potential: A Review,
2020
Naresuan University, Phitsanulok, Thailand
The Analytical And Biomedical Applications Of Carbon Dots And Their Future Theranostic Potential: A Review, Sukunya Ross, Ren-Siang Wu, Shih-Chun Wei, Gareth M. Ross, Huan-Tsung Chang
Journal of Food and Drug Analysis
In recent years, carbon dots (C-dots) have gained appreciable interest owing to their unique optical properties, including tunable fluorescence, stability against photobleaching and photoblinking, and strong fluorescence. Simple and low-cost hydrothermal and electrochemical approaches have been widely used in the preparation of biocompatible and high-quality C-dots. Various C-dots have been used for the quantitation of small analytes, mostly based on analyte induced fluorescence quenching. Depending on the nature of precursors, synthetic conditions (such as reaction temperature and time), and surface conjugation, multi-function C-dots can be prepared and used in diagnostics and therapeutics. Their strong fluorescence and photostability, enables use in …
Nanomaterial-Based Adsorbents And Optical Sensors For Illicit Drug Analysis,
2020
Kaohsiung Medical University, Kaohsiung, Taiwan
Nanomaterial-Based Adsorbents And Optical Sensors For Illicit Drug Analysis, Chun-Hsien Chen, Chun-Chi Wang, Po-Yun Ko, Yen-Ling Chen
Journal of Food and Drug Analysis
The abuse of illicit drugs has been prevalent in recent years and is associated with crime and public health issues. To strengthen public security and fortify public health services with respect to the increasing severity of drug abuse, academic and government institutes have been devoted to constructing relative analytical methods for illicit drugs. To date, the development of sensors has been greatly emphasized due to their features of high sensitivity, prompt detection and flexible manipulation; thus, sensors can serve as alternatives to conventional sophisticated instruments. Recently, the use of nanomaterials has inspired the development of a series of innovative sample …
Gold Nanoparticle-Based Colorimetric And Electrochemical Sensors For The Detection Of Illegal Food Additives,
2020
Nanjing Medical University, Lianyungang, PR China
Gold Nanoparticle-Based Colorimetric And Electrochemical Sensors For The Detection Of Illegal Food Additives, Li Li, Ming Zhang, Wei Chen
Journal of Food and Drug Analysis
Lately, scandals associated with the illegal addition of poisonous chemicals to food for commercial interests have been gradually disclosed to the public. Problems related to food safety do not only harm public health but also affect the stability of economic and social development. Food safety has become a common issue in society, and strengthening the related regulations have become increasingly important. Although conventional techniques are accurate and sensitive in the detection of the vast majority of illegal food additives, they rely on time-consuming, labor-intensive procedures that depend on expensive instruments. Thus, efficient and rapid identification of poisonous, illegal additives in …
Improved Food Additive Analysis By Ever-Increasing Nanotechnology,
2020
University of Chemical Technology, Beijing, China
Improved Food Additive Analysis By Ever-Increasing Nanotechnology, Jing Zhang, Shui Hu, Yi Du, Ding Cao, Guirong Wang, Zhiqin Yuan
Journal of Food and Drug Analysis
Improper use of food additives may lead to potential threat to human health, making it important to develop sensitive and selective method for the detection of them. Nanomaterials with unique chemical and electrochemical properties show extensive applications in the design of food additive sensing systems. In this review, we summarize the recently adopted electrochemical and optical analysis of food additives based on nanomaterials. Detection of typical food additives (colorants and preservatives) by using different sensing mechanisms and strategies are provided. In addition, determination of illegal food additives is also briefly introduced. Finally, this review highlights the challenges and future trend …
Electrowetting-On-Dielectric (Ewod): Current Perspectives And Applications In Ensuring Food Safety,
2020
National Tsing Hua University, Hsinchu, Taiwan
Electrowetting-On-Dielectric (Ewod): Current Perspectives And Applications In Ensuring Food Safety, Snigdha Roy Barman, Imran Khan, Subhodeep Chatterjee, Subhajit Saha, Dukhyun Choi, Sangmin Lee, Zong-Hong Lin
Journal of Food and Drug Analysis
Digital microfluidic (DMF) platforms have contributed immensely to the development of multifunctional lab-on-chip systems for performing complete sets of biological and analytical assays. Electrowetting-on-dielectric (EWOD) technology, due to its outstanding flexibility and integrability, has emerged as a promising candidate for such lab-on-chip applications. Triggered by an electrical stimulus, EWOD devices allow precise manipulation of single droplets along the designed electrode arrays without employing external pumps and valves, thereby enhancing the miniaturization and portability of the system towards transcending important laboratory assays in resource-limited settings. In recent years, the simple fabrication process and reprogrammable architecture of EWOD chips have led to …
Nanomaterial-Based Fluorescent Biosensor For Veterinary Drug Detection In Foods,
2020
Southwest University, Chongqing, China
Nanomaterial-Based Fluorescent Biosensor For Veterinary Drug Detection In Foods, Xiaoqi Tao, Yuanyuan Peng, Juewen Liu
Journal of Food and Drug Analysis
Veterinary drugs have been widely used in the food industry. Their residues in food products need to be tightly regulated to ensure food safety. In particular, some veterinary drugs are still used illegally, although they have already been banned. Nanomaterials are playing an increasingly important role in analytical chemistry due to their unique properties. Compared to traditional organic dyes and colloidal gold nanoparticle labels, fluorescent nanomaterials appear particularly attractive for the detection of veterinary drug residues. This review summarizes recent advancements of fluorescent biosensors using nanomaterials for the detection of veterinary drug residues in foods. The useful properties of each …
Carbon Quantum Dots For The Detection Of Antibiotics And Pesticides,
2020
National Taiwan Ocean University, Keelung, Taiwan
Carbon Quantum Dots For The Detection Of Antibiotics And Pesticides, Han-Wei Chu, Binesh Unnikrishnan, Anisha Anand, Yang-Wei Lin, Chih-Ching Huang
Journal of Food and Drug Analysis
Carbon quantum dots (CQDs) are novel nanomaterials with interesting physical and chemical properties, which are intensely studied only in the last decade. Unique properties, such as its inherent fluorescent property, high resistance to photobleaching, high surface area, ease of synthesis, flexible choice of precursor, and surface tunability enable CQDs for promising application in biosensing. Therefore, it is highly useful in clinical, forensic, medical, food and drug analyses, disease diagnosis, and various other fields of biosensing. In addition, their fluorescence properties are tunable by the interaction with certain molecules via different mechanisms, which enables their application for sensing of those molecules, …
Noble Metal Nanomaterial-Based Aptasensors For Microbial Toxin Detection,
2020
Southwest University, Chongqing, China
Noble Metal Nanomaterial-Based Aptasensors For Microbial Toxin Detection, Yue He, Cong-Ying Wen, Zhi-Jun Guo, Yu-Fen Huang
Journal of Food and Drug Analysis
Microbial toxins generated by bacteria, fungi and algae cause serious food-safety problems due to the frequent contamination of foodstuffs and their poisonous nature. Becoming acquainted with the contamination condition of foodstuffs is highly dependent on developing sensitive, specific, and accurate methods for targeting microbial toxins. Aptamers, obtained from systematic evolution of ligands by exponential enrichment (SELEX), have significant advantages for microbial toxin analysis, such as small size, reproducible chemical synthesis, and modification, as well as high binding affinity, specificity, and stability. Besides, aptamers have a predictable structure and can be tailored using biomolecular tools (e.g., ligase, endonuclease, exonuclease, …
Perspective On Recent Developments Of Nanomaterial Based Fluorescent Sensors: Applications In Safety And Quality Control Of Food And Beverages,
2020
Tianjin University of Science and Technology, Tianjin, China
Perspective On Recent Developments Of Nanomaterial Based Fluorescent Sensors: Applications In Safety And Quality Control Of Food And Beverages, Ailing Han, Sijia Hao, Yayu Yang, Xia Li, Xiaoyu Luo, Guozhen Fang, Jifeng Liu, Shuo Wang
Journal of Food and Drug Analysis
As the highly toxic pollutants will seriously harm human health, it is particularly important to establish the analysis and detection technology of food pollutants. Compared with the traditional detection methods, fluorescent detection technique based on nanomaterials trigger wide interesting because of reduced detection time, simple operation, high sensitivity and selectivity and economic. In this review, the application of fluorescent sensors in food pollutants detection is presented. Firstly, conventional fluorescent nanomaterials including metal-based quantum dots, carbon-based quantum dots and metal nanoclusters were summarized, with emphasis on the photoluminescence mechanism. Then, the fluorescence sensors based on these nanomaterials for food pollutants detection …
Preface,
2020
National Taiwan University, Taiwan
Preface, Huan-Tsung Chang, Yu-Fen Huang
Journal of Food and Drug Analysis
No abstract provided.
Dendriplex - Cyclodextrin Conjugates For Gene Delivery To Retina,
2020
University of South Florida
Dendriplex - Cyclodextrin Conjugates For Gene Delivery To Retina, Durga Deepak Puro
USF Tampa Graduate Theses and Dissertations
Gene therapy holds promise for treating a wide range of diseases including cancer and several other polygenic and monogenic disorder arising in different organs. Due to its immune privilege nature, eye is an ideal organ for gene therapy,as various visual pathologies arise from gene defect and can lead to partial or complete vision loss. The last decade, several nanoparticles have been developed and tested for their transfection efficiency in vitro and in vivo. Among them, dendrimers with small size, good physicochemical properties and endosomal escape activity have shown high transfection efficiency in various cell lines. In an attempt to further …
Examining Sodium And Potassium Channel Conductances Involved In Hyperexcitability Of Chemotherapy-Induced Peripheral Neuropathy: A Mathematical And Cell Culture-Based Study,
2020
Purdue University
Examining Sodium And Potassium Channel Conductances Involved In Hyperexcitability Of Chemotherapy-Induced Peripheral Neuropathy: A Mathematical And Cell Culture-Based Study, Parul Verma, Muriel Eaton, Achim Kienle, Dietrich Flockerzi, Yang Yang, Doraiswami Ramkrishna
Purdue University Libraries Open Access Publishing Fund
Chemotherapy-induced peripheral neuropathy (CIPN) is a prevalent, painful side effect which arises due to a number of chemotherapy agents. CIPN can have a prolonged effect on quality of life. Chemotherapy treatment is often reduced or stopped altogether because of the severe pain. Currently, there are no FDA-approved treatments for CIPN partially due to its complex pathogenesis in multiple pathways involving a variety of channels, specifically, voltage-gated ion channels. One aspect of neuropathic pain in vitro is hyperexcitability in dorsal root ganglia (DRG) peripheral sensory neurons. Our study employs bifurcation theory to investigate the role of voltage-gated ion channels in inducing …
Chemical Composition Of The Volatile Fractions Of Mesembryanthemum Forskahlei Flowers And Herb,
2020
Al Jouf University - Kingdom of Saudi Arabia
Chemical Composition Of The Volatile Fractions Of Mesembryanthemum Forskahlei Flowers And Herb, Moeen Dababneh
Al Jinan الجنان
Halophytes are succulent native plants to the northern region of the Kingdom of Saudi Arabia. They have therapeutic properties and can be potentially useful as a new source of bioactive compounds. Our study aims to investigate the chemical composition of the volatile fraction of Herb and Flowers of Mesembryanthemum forskahlei by the application of Gas Chromatography method. Our study showed that palmetic acid (420mg/ kg) and squaline (352,32mg/kg) are the main components in the herb. Furthermore, we identified that palmitic acid is the main component of the flower. Finally, Mesembryanthemum forskahlei herb has higher content of volatile compounds than the …
Corrigendum To “Physicochemical Analysis And Nonisothermal Kinetic Study Of Sertralineelactose Binary Mixtures”,
2020
Taiwan Food and Drug Administration
Corrigendum To “Physicochemical Analysis And Nonisothermal Kinetic Study Of Sertralineelactose Binary Mixtures”, Farnaz Monajjemzadeh
Journal of Food and Drug Analysis
No abstract provided.
Corrigendum To “Shenmai-Yin Decreased The Clearance Of Nifedipine In Rats: The Involvement Of Time-Dependent Inhibition Of Nifedipine Oxidation”,
2020
Taiwan Food and Drug Administration
Corrigendum To “Shenmai-Yin Decreased The Clearance Of Nifedipine In Rats: The Involvement Of Time-Dependent Inhibition Of Nifedipine Oxidation”, Yune- Fang Ueng
Journal of Food and Drug Analysis
No abstract provided.
Corrigendum To “The Time-Dependent Effects Of St John's Wort On Cytochrome P450, Uridine Diphosphate-Glucuronosyltransferase, Glutathione S-Transferase, And Nad(P)H-Quinone Oxidoreductase In Mice”,
2020
Taiwan Food and Drug Administration
Corrigendum To “The Time-Dependent Effects Of St John's Wort On Cytochrome P450, Uridine Diphosphate-Glucuronosyltransferase, Glutathione S-Transferase, And Nad(P)H-Quinone Oxidoreductase In Mice”, Yune- Fang Ueng
Journal of Food and Drug Analysis
No abstract provided.
Corrigendum To “Effects Of Aqueous Extract Of Ruta Graveolens And Its Ingredients On Cytochrome P450, Uridine Diphosphate (Udp)-Glucuronosyltransferase, And Reduced Nicotinamide Adenine Dinucleotide (Phosphate) (Nad(P)H)-Quinone Oxidoreductase In Mice”,
2020
Taiwan Food and Drug Administration
Corrigendum To “Effects Of Aqueous Extract Of Ruta Graveolens And Its Ingredients On Cytochrome P450, Uridine Diphosphate (Udp)-Glucuronosyltransferase, And Reduced Nicotinamide Adenine Dinucleotide (Phosphate) (Nad(P)H)-Quinone Oxidoreductase In Mice”, Yune- Fang Ueng
Journal of Food and Drug Analysis
No abstract provided.
Acarbose Attenuates Migration/Proliferation Via Targeting Microrna-143 In Vascular Smooth Muscle Cells Under Diabetic Conditions,
2020
Chung-Shan Medical University Hospital, Taiwan
Acarbose Attenuates Migration/Proliferation Via Targeting Microrna-143 In Vascular Smooth Muscle Cells Under Diabetic Conditions, Wei-Yuan Chuang, Meng-Hsun Yu, Tsung-Yuan Yang, Kuei-Chuan Chan, Chau-Jong Wang
Journal of Food and Drug Analysis
Acarbose (an a-glucosidase inhibitor) has been demonstrated to reduce the progression of atherosclerosis without affecting serum levels of glucose in rabbits fed a high cholesterol diet. The main focus of recent atherosclerosis studies has been microRNA targets. However, the mechanism by which acarbose targets miRNA-mediated atherosclerosis remains unclear. This study aimed to evaluate the effect of acarbose on microRNA-related regulation of rat aortic vascular smooth cell line (A7r5 cell) migration and proliferation induced by diabetic conditions. We reported that acabose exhibit significantly inhibits proliferative and cell migration abilities in A7r5 cells. The expression of protein and levels of mRNA were …
Effect Of 6,7-Dimethoxy-2,2-Dimethyl-2h-Chromene (Agerarin) On The Recovery Of Filaggrin Expression Through Targeting Of Janus Kinases In The Inflammatory Skin,
2020
Konkuk University, Seoul, Republic of Korea
Effect Of 6,7-Dimethoxy-2,2-Dimethyl-2h-Chromene (Agerarin) On The Recovery Of Filaggrin Expression Through Targeting Of Janus Kinases In The Inflammatory Skin, Sung Shin Ahn, Young Han Lee, Hyunjin Yeo, Youngshim Lee, Do Sik Min, Yoongho Lim, Soon Young Shin
Journal of Food and Drug Analysis
Filaggrin (FLG) is a structural component of the stratum corneum that is essential for maintaining the barrier function of the skin and for the formation of natural moisturizing factors. 6,7-Dimethoxy-2,2-dimethyl-2H-chromene (Agerarin) is a bioactive compound derived from Ageratum houstonianum, a plant that is used as a traditional medicine to treat skin diseases. This study aimed to evaluate the effect of agerarin on skin inflammation in a dinitrochlorobenzene (DNCB)-induced atopic dermatitis mouse model. We found that the topical administration of agerarin ameliorates atopic dermatitis-like skin lesions. We also showed that agerarin restores the reduced filaggrin (FLG) expression in …
Biologically-Guided Isolation Of Natural Lead Antithyroid Drug From Medicago Sativa L. Sprouts And Its Toxic Profile In Comparison With Propylthiouracil,
2020
Alexandria University, Egypt
Biologically-Guided Isolation Of Natural Lead Antithyroid Drug From Medicago Sativa L. Sprouts And Its Toxic Profile In Comparison With Propylthiouracil, Reham S. Ibrahim, Nesrine S. El-Mezayen, Asmaa Khairy, Hala H. Zaatout, Hala M. Hammoda, Aly M. Metwally
Journal of Food and Drug Analysis
Hyperthyroidism is a common endocrine disorder associated with increased risk of cardiovascular complications and mortality. Although antithyroid drugs (ATDs) are approved as first line option for many hyperthyroidism cases, including pregnancy and childhood, they exert significant toxic profile. Medicago sativa L. (alfalfa) also called “The father of all food” was among the diet consumed by mares that gave birth to foals with congenital hypothyroidism. Since, greenfeed was accused for the development of such condition, alfalfa may possess constituents with promising antithyroid potential that could be a valuable substitute for the conventional ATDs. The current work was designed to identify the …
