Brain Bioavailability Of Polyphenols: Implications For Delivery Of Brain Health Benefits,
2013
Purdue University
Brain Bioavailability Of Polyphenols: Implications For Delivery Of Brain Health Benefits, Tzu-Ying Chen
Open Access Dissertations
Consumption of fruits and vegetables has been associated with neuroprotection and cognitive benefits throughout the life span. These associations have sparked interest in plant-derived polyphenols as biologically active agents with potential for targeting brain benefits. However, little is known regarding the ability of the polyphenols or their metabolites from polyphenol-rich products to cross the blood-brain-barrier, and be available for biological action. Furthermore, additional insight is needed on factors affecting the absorption and brain distribution of polyphenol metabolites in vivo. To fill gap in current knowledge, this thesis will focus on the effects of diabetogenic diet and diabetic state which have …
Metabolic Characterization Of A Sirt5 Deficient Mouse Model,
2013
Ecole Polytechnique Federale de Lausanne
Metabolic Characterization Of A Sirt5 Deficient Mouse Model, Jiujiu Yu, Sushabhan Sadhukhan, Lilia G. Noriega, Norman Moullan, Bin He, Robert S. Weiss, Hening Lin, Kristina Schoonjans, Johan Auwerx
Department of Nutrition and Health Sciences: Faculty Publications
Sirt5, localized in the mitochondria, is a member of sirtuin family of NAD1-dependent deacetylases. Sirt5 was shown to deacetylate and activate carbamoyl phosphate synthase 1. Most recently, Sirt5 was reported to be the predominant protein desuccinylase and demalonylase in the mitochondria because the ablation of Sirt5 enhanced the global succinylation and malonylation of mitochondrial proteins, including many metabolic enzymes. In order to determine the physiological role of Sirt5 in metabolic homeostasis, we generated a germline Sirt5 deficient (Sirt52/2) mouse model and performed a thorough metabolic characterization of this mouse line. Although a global protein hypersuccinylation and elevated serum ammonia during …
Tissue And Intracellular Distribution Kinetics Of Vitamin K,
2013
Brigham Young University
Tissue And Intracellular Distribution Kinetics Of Vitamin K, David Hunt, Dr. Robert Davidson
Journal of Undergraduate Research
In June of 2003 I began studying the metabolism kinetics of vitamin K in the Sprague-Dawley rat under the tutelage of Dr. Robert Davidson. This work has since developed into the body of my proposed Master’s thesis. This letter is intended to communicate the progress of this research.
Preventing Malnutrition Within Ecuador,
2013
Brigham Young University
Preventing Malnutrition Within Ecuador, Tiffany Covington, Dr. Alison Campbell
Journal of Undergraduate Research
La Rinconada is a unique indigenous village tucked away in the northern mountainous regions of Imbabura, Ecuador where the children of local subsistence farmers suffer from nutritional deficiencies. Studies completed by The Benson Institute show that before the year 2000, 50 percent of the villagers did not consume vegetables. Similar studies also show that meat consumption was often saved and therefore not consumed except for special occasions. Macro and micro-nutrient deficiencies within the children are evident through stunted growth patterns, hair discoloration, loss of eyesight, and premature death.
Food Insecurity Among Children In Massachusetts,
2013
Boston University
Food Insecurity Among Children In Massachusetts, Stephanie Ettinger De Cuba, Deborah A. Frank, Maya Pilgrim, Maria Buitrago, Anna Voremberg, Harris Rollinger, Denise A. Hines
New England Journal of Public Policy
This article focuses on the prevalence among Massachusetts children and families of food insecurity, inadequate access to enough nutritious food for an active and healthy life. It summarizes research findings on the association of food insecurity with less optimal children’s health and development from the prenatal period through adolescence. Food insecurity also correlates with other material hardships, such as housing and energy insecurity. Data show families’ participation in public nutrition and other assistance program is associated with decreased prevalence of food insecurity and with mitigation of its impact on children’s health and well-being. The article concludes with recommendations for policy …
Agriculture And The Food System: A Short History And Country Case Study In Mongolia,
2013
SIT Graduate Institute
Agriculture And The Food System: A Short History And Country Case Study In Mongolia, Marissa L. Markowitz
Capstone Collection
This paper includes a brief history of the human food system. It includes an exploration of the formation of the food system, the development of the modernized food and agriculture system, and challenges arisen throughout. Additionally, a specific case study into Mongolia and the unique geography of its food system is highlighted. The purpose of providing the case study is to consider challenges of a food system in transition amidst development in one country. Recommendations for Mongolia anent sustainable development are provided.
Predicting Regional Circumferences From Regional Body Composition Data,
2013
Brigham Young University
Predicting Regional Circumferences From Regional Body Composition Data, Toria Mcmullin, Dr. Robert T. Davidson
Journal of Undergraduate Research
Due to the current trend obesity rates and the increased public awareness of the connection between body composition and health, individuals are becoming more and more interested in assessing and changing their own body composition. The current methods used to assess body composition include the following: dual-energy x-ray absorptiometry (DEXA), computerized tomography (CT) scans, magnetic resonance imaging (MRI), bioelectric impedance analysis (BIA), Near-Infrared Interactance (NIR), BodPod measurements, skinfold and circumference anthropometric measurements, and hydrodensitometry. Multicomponent models most accurately predict body composition. However, such models—including hydrodensitometry and DEXA—are either too difficult or too costly for practical, widespread consideration. Other methods are …
The Effect Of Isoflavone And Selenium Diets On Body Composition (Biochemical Responses To Phytoestrogen And Selenium Diets In Noble Rats Relating To Reduced Prostate Cancer Risk),
2013
Brigham Young University
The Effect Of Isoflavone And Selenium Diets On Body Composition (Biochemical Responses To Phytoestrogen And Selenium Diets In Noble Rats Relating To Reduced Prostate Cancer Risk), Jessica Tolman, Dr. Merrill J. Christensen
Journal of Undergraduate Research
The intent of the following research was to fulfill the thesis requirements for the BYU Honors Program, the following report is complied from excerpts from my Honors Thesis. The results were presented at the 8th International Symposium on Selenium in Biology and Medicine. At the beginning of this project I focused my interests on the effect of isoflavone and selenium on body composition. I later used these findings and the effect of isoflavone and selenium on hormone serum levels to determine the effect of isoflavone and selenium on prostate cancer risk.
The Antimicrobial Effects Of Honey Against H. Pylori,
2013
Brigham Young University
The Antimicrobial Effects Of Honey Against H. Pylori, Walker Berkley, Dr. Frost Steele
Journal of Undergraduate Research
In 2005 Dr. Marshall, along with co-discoverer Dr, J Robin Warren, shared the Nobel Prize in Physiology or Medicine for their linking the bacteria H. pylori to gastric ulcers and instituting regiments of antibiotic treatments that culminated in the first long term cure for this dehabilitating stomach condition.
The Association Between Expectancies For Success And In-Season Dietary Practices Among A Group Of Female High School Softball Players,
2013
Brigham Young University
The Association Between Expectancies For Success And In-Season Dietary Practices Among A Group Of Female High School Softball Players, Elizabeth M. Crowley, Dr. Lora Beth Brown
Journal of Undergraduate Research
Coaches and trainers need to be aware of the dietary practices of their athletes and strive to encourage their players to engage in healthy and proper nutrition. The purpose of this study was twofold: 1) assess the dietary and nutrition practices of a group of female high school basketball players, and 2) to determine if expectancies for achievement and success are associated with better eating practices. Understanding the latter, may be useful in helping high school coaches devise ways to motivate players to improve their eating habits.
Bone Ashing To Measure The Effects Of Vitamin K In Bone Mineral Density In Rats,
2013
Brigham Young University
Bone Ashing To Measure The Effects Of Vitamin K In Bone Mineral Density In Rats, Michael Draney, Dr. Robert Davidson
Journal of Undergraduate Research
Millions of people throughout the world suffer from osteoporosis. It is a degenerative disease that is characterized by increased bone fragility and decreased bone mineral and bone density.
Dxa Scan Analysis Of The Reducing Effect Of Vitamin K And Omega-3 On Bone Mineral Loss In Ovariectomized (Ovx) Sprague-Dawley Rats,
2013
Brigham Young University
Dxa Scan Analysis Of The Reducing Effect Of Vitamin K And Omega-3 On Bone Mineral Loss In Ovariectomized (Ovx) Sprague-Dawley Rats, Stephen Roberts, Dr. Robert Davidson
Journal of Undergraduate Research
Vitamin K, long established as important for blood clotting, has received more recent attention regarding a role in bone metabolism and remodeling.1 Vitamin K could potentially be an effective treatment in reducing the deleterious effect of osteoporosis.
The Effect On Femur Bone Tensile Strength And Calcium Levels In Osteoporosis Induced Rats By Vitamin K Supplementation,
2013
Brigham Young University
The Effect On Femur Bone Tensile Strength And Calcium Levels In Osteoporosis Induced Rats By Vitamin K Supplementation, Ryan Probst, Dr. Robert T. Davidson
Journal of Undergraduate Research
Osteoporosis is a growing problem in the world today. With the aging population of the United State’s Baby Boomer generation, healthcare research is shifting dramatically to combat the rising rates of diseases associated with our aging population majority. Compiled with this majority of elderly people is the fact that Americans are living longer. We must face the challenges associated with the aging human body. Osteoporosis is an age-related disease. This study has added to the research available on osteoporosis and has provided enhanced methods to treat osteoporosis, a major problem especially in postmenopausal women. Several Asian studies report an increase …
Review Of Report On The “Status Of Nearshore Finfish Stocks In South-Western Western Australia: Australian Herring And Tailor”,
2013
Department of Primary Industries and Regional Development, Western Australia
Review Of Report On The “Status Of Nearshore Finfish Stocks In South-Western Western Australia: Australian Herring And Tailor”, Department Of Fisheries
Fisheries Occasional Publications
No abstract provided.
Pass The Pecans,
2013
Andrews University
Overcoming Shortage Of Pharmacists To Provide Pharmaceutical Services In Public Health Centers In Indonesia,
2013
Pusat Teknologi Intervensi Kesehatan Masyarakat Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan Indonesia
Overcoming Shortage Of Pharmacists To Provide Pharmaceutical Services In Public Health Centers In Indonesia, Yuyun Yuniar, Max Joseph Herman
Kesmas
Indonesia masih menghadapi keterbatasan jumlah apoteker di puskesmas, sehingga pihak pemerintah daerah dan puskesmas harus berupaya mengatasi permasalahan tersebut. Penelitian ini bertujuan untuk menggambarkan ketersediaan dan distribusi tenaga pelayanan kefarmasian di puskesmas serta permasalahan dan alternatif pemecahannya. Data diambil dari hasil Riset Fasilitas Kesehatan (Rifaskes) tahun 2011I. Data kuantitatif tentang tenaga pelayanan kefarmasian di puskesmas dianalisis secara deskriptif berdasarkan regional. Data kualitatif sebagai pendukung diperoleh melalui wawancara mendalam dengan bagian kepegawaian dinas kesehatan dan apoteker empat puskesmas di Kota Bogor dan Bekasi, 3 kemudian dianalisis dengan metode analisis tema. Hasil analisis menunjukkan bahwa Sulawesi memiliki persentase puskesmas dengan tenaga apoteker …
Effect Of Selenium On The Expression Of The Androgen Receptor And Nuclear Factor Kappa-B In Human Prostate Cancer Cells,
2013
Brigham Young University
Effect Of Selenium On The Expression Of The Androgen Receptor And Nuclear Factor Kappa-B In Human Prostate Cancer Cells, Daniel Tandberg, Dr. Merrill J. Christensen
Journal of Undergraduate Research
Selenium has been established as a promising chemopreventive element for prostate cancer. Several different mechanisms have been studied to delineate selenium’s anti-cancer effect, but the exact target and mechanism has yet to be clearly defined. Previous studies have established an inhibitory relationship between the nuclear factor kappa B (NF-κB) and selenium, as well as the Androgen Receptor (AR) and selenium in human LNCap cells. Both NF-κB and AR are constituently active during prostate cancer development, and their deactivation by selenium might be one of the mechanisms by which selenium acts as a chemopreventative agent. The purpose of our research is …
The Derivatives Of Resveratrol And Prostate Cancer,
2013
Brigham Young University
The Derivatives Of Resveratrol And Prostate Cancer, Dallin Snow, Dr. Merrill Christensen
Journal of Undergraduate Research
Resveratrol has been shown to be a very effective anticarcinogenic compound, in addition to its anti-viral, anti-aging, anti-inflammatory, and life prolonging effects. Resveratrol binds the estrogen receptor beta which in turn down regulates the androgen receptor, which is active in prostate cancer. Past studies of the effects of resveratrol on human prostate cancer cells have shown that it increases the rate of apoptosis and decreases proliferation in a dose and time dependent manner (Benitez, 2007). Also, a 2004 study exploring the absorption and metabolism of resveratrol in humans indicated that it is metabolized at a rapid rate by humans. It …
The Effect Of Selenium On Nuclear Factor-Κb And Androgen Receptor Expression In Human Prostate Cancer Cells,
2013
Brigham Young University
The Effect Of Selenium On Nuclear Factor-Κb And Androgen Receptor Expression In Human Prostate Cancer Cells, Daniel Tandberg, Dr. Merrill J. Christensen
Journal of Undergraduate Research
According to the American Cancer Society prostate cancer is the second most commonly diagnosed cancer, as well as the second most common cause of cancer death in the United States. The trace mineral and essential nutrient selenium has been established as a promising chemopreventive element for prostate cancer. Plant foods are the best source of selenium; however, the selenium content of plants varies significantly based on the soil in which it was grown in. This study attempted to provide further insight into the molecular mechanism by which selenium effects cancer development. Specifically we looked at the expression of the Nuclear …
Factors Affecting Folic Acid Stability In Micronutrient Fortified Corn Tortillas,
2013
Brigham Young University
Factors Affecting Folic Acid Stability In Micronutrient Fortified Corn Tortillas, Kirk Oler
Journal of Undergraduate Research
The previously submitted grant application outlined research methods that would use ORCA funding. This report is a follow up to the initial ORCA grant application. First, a brief recapitulation of the grant application will be provided. Second will be a description of the actual research with any deviations from the application. Third, the results of the research will be presented.
