Quantifying Cognitive Function In Concussed Athletes Before And After Acute Exercise Using A Choice Reaction Time Task,
2014
Wilfrid Laurier University
Quantifying Cognitive Function In Concussed Athletes Before And After Acute Exercise Using A Choice Reaction Time Task, Stephanie A. Ramautar M.Sc., Michael E. Cinelli Ph.D.
Theses and Dissertations (Comprehensive)
Following a concussion, cognitive deficits have been shown to last longer than symptom resolution. Currently clinicians rely heavily on symptom emergence following the fundamental exercises of the return to play (RTP) protocol, which may leave athletes at risk of returning to play too early if cognitive deficits have not been detected. The purpose of this study was to assess the effects of exercise on choice reaction time (CRT) both at rest and following an acute exercise in 3 populations: non-concussed (NC), recently concussed (RC), and post-concussion syndrome (PCS) individuals. A CRT task in the form of an iPad application measured …
Spatial Warping By Oriented Line Detectors Can Counteract Neural Delays,
2013
Department of Neuroscience, Baylor College of Medicine Houston, TX, USA.
Spatial Warping By Oriented Line Detectors Can Counteract Neural Delays, Don A. Vaughn, David M. Eagleman
Faculty, Staff and Students Publications
The slow speed of neural transmission necessitates that cortical visual information from dynamic scenes will lag reality. The "perceiving the present" (PTP) hypothesis suggests that the visual system can mitigate the effect of such delays by spatially warping scenes to look as they will in ~100 ms from now (Changizi, 2001). We here show that the Hering illusion, in which straight lines appear bowed, can be induced by a background of optic flow, consistent with the PTP hypothesis. However, importantly, the bowing direction is the same whether the flow is inward or outward. This suggests that if the warping is …
Network Structure And Dynamics Of The Mental Workspace,
2013
Dartmouth College
Network Structure And Dynamics Of The Mental Workspace, Alexander Schlegel, Peter J. Kohler, Sergei V. Fogelson, Prescott Alexander
Dartmouth Scholarship
The conscious manipulation of mental representations is central to many creative and uniquely human abilities. How does the human brain mediate such flexible mental operations? Here, multivariate pattern analysis of functional MRI data reveals a widespread neural network that performs specific mental manipulations on the contents of visual imagery. Evolving patterns of neural activity within this mental workspace track the sequence of informational transformations carried out by these manipulations. The network switches between distinct connectivity profiles as representations are maintained or manipulated.
The Flexible Fairness: Equality, Earned Entitlement, And Self-Interest,
2013
Beijing Normal University, China
The Flexible Fairness: Equality, Earned Entitlement, And Self-Interest, Chunliang Feng, Yi Luo, Ruolei Gu, Lucas S. Broster, Xueyi Shen, Tengxiang Tian, Yue-Jia Luo, Frank Krueger
Behavioral Science Faculty Publications
The current study explored whether earned entitlement modulated the perception of fairness in three experiments. A preliminary resource earning task was added before players decided how to allocate the resource they jointly earned. Participants' decision in allocation, their responses to equal or unequal offers, whether advantageous or disadvantageous, and subjective ratings of fairness were all assessed in the current study. Behavioral results revealed that participants proposed more generous offers and showed enhanced tolerance to disadvantageous unequal offers from others when they performed worse than their presumed "partners," while the reverse was true in the better-performance condition. The subjective ratings also …
Unconscious Priming Requires Early Visual Cortex At Specific Temporal Phases Of Processing,
2013
CUNY Graduate Center
Unconscious Priming Requires Early Visual Cortex At Specific Temporal Phases Of Processing, Marjan Persuh, Tony Ro
Publications and Research
Although examples of unconscious shape priming have been well documented, whether such priming requires early visual cortex (V1/V2) has not been established. In the current study, we used TMS of V1/V2 at varying temporal intervals to suppress the visibility of preceding shape primes while the interval between primes and targets was kept constant. Our results show that, although conscious perception requires V1/V2, unconscious priming can occur without V1/V2 at an intermediate temporal interval but not at early (5–25 msec) or later (65–125 msec) stages of processing. Because the later time window of unconscious priming suppression has been proposed to interfere …
Network Dynamics Of Visual Naming,
2013
The University of Texas Graduate School of Biomedcial Sciences at Houston
Network Dynamics Of Visual Naming, Christopher R. Conner
Dissertations and Theses (Open Access)
Recognition and naming of objects and actions are fundamental components of language. They involve several different systems working in coordination to accomplish a complex behavior. During visual naming, sensory and semantic processing are carried out by dedicated cortical substrates in the temporal and occipital lobes, while response selection and articulatory planning are handled by prefrontal cortex. Despite decades of research using lesion analysis, functional MRI and electro-encephalography, the precise dynamics involved remain unknown due to the inadequate spatio-temporal resolution of these methodologies. Of particular interest is the organization of semantic knowledge and the degree of serial and parallel organization of …
What Can The Organization Of The Brain’S Default Mode Network Tell Us About Self-Knowledge?,
2013
Harvard University
What Can The Organization Of The Brain’S Default Mode Network Tell Us About Self-Knowledge?, Joseph. M. Moran, William M. Kelley, Todd F. Heatherton
Dartmouth Scholarship
Understanding ourselves has been a fundamental topic for psychologists and philosophers alike. In this paper we review the evidence linking specific brain structures to self-reflection. The brain regions most associated with self-reflection are the posterior cingulate and medial prefrontal (mPFC) cortices, together known as the cortical midline structures (CMSs). We review evidence arguing that self-reflection is special in memory, while noting that these brain regions are often engaged when we think about others in our social worlds. Based on the CMSs’ patterns of connectivity and activity, we speculate about three possible interpretations of their role in supporting self-reflection that are …
Decades-Long Social Memory In Bottlenose Dolphins,
2013
Stephen F Austin State University
Decades-Long Social Memory In Bottlenose Dolphins, Jason N. Bruck
Faculty Publications
Long-term social memory is important, because it is an ecologically relevant test of cognitive capacity, it helps us understand which social relationships are remembered and it relates two seemingly disparate disciplines: cognition and sociality. For dolphins, long-term memory for conspecifics could help assess social threats as well as potential social or hunting alliances in a very fluid and complex fission-fusion social system, yet we have no idea how long dolphins can remember each other. Through a playback study conducted within a multi-institution dolphin breeding consortium (where animals are moved between different facilities), recognition of unfamiliar versus familiar signature whistles of …
Evaluation Of A Short-Form Of The Berg Card Sorting Test,
2013
Portland State University
Evaluation Of A Short-Form Of The Berg Card Sorting Test, Christopher J. Fox, Shane T. Mueller, Hilary M. Gray, Jacob Raber, Brian J. Piper
Psychology Faculty Publications and Presentations
The Psychology Experimental Building Language http://pebl.sourceforge.net/Berg Card Sorting Test is an open-source neurobehavioral test. Participants (N = 207, ages 6 to 74) completed the Berg Card Sorting Test. Performance on the first 64 trials were isolated and compared to that on the full-length (128 trials) test. Strong correlations between the short and long forms (total errors: r = .87, perseverative response: r = .83, perseverative errors r = .77, categories completed r = .86) support the Berg Card Sorting Test-64 as an abbreviated alternative for the full-length executive function test.
Moving To The Beat: Musical Rhythm As A Cipher For Priming, Synchronizing, And Entrainment In The Premotor Cortex,
2013
DePauw University
Moving To The Beat: Musical Rhythm As A Cipher For Priming, Synchronizing, And Entrainment In The Premotor Cortex, Mikey Padilla '13
Honor Scholar Theses
Music is both a universal and persistent cultural phenomenon. One of the defining features of music is rhythm. The ability of rhythm to affect and be affected by movement has been deeply characterized in neuroscience research and literature. There is a great deal of research implicating the involvement of the dorsal premotor cortex in rhythm perception and production through the auditory–motor pathway (Repp, 2005; Zatorre, Chen, and Penhune, 2007; Repp and Su, 2013). “Chunking” (Sakai, Hikosaka, and Nakamura, 2004) and template-matching (Warren, Wise, and Warren, 2005) are two significant mechanisms in the auditory–motor pathway. In this thesis, two interrelated theories …
Getting A Grip On Memory: Unilateral Hand Clenching Alters Episodic Recall,
2013
Montclair State University
Getting A Grip On Memory: Unilateral Hand Clenching Alters Episodic Recall, Ruth E. Propper, Sean E. Mcgraw, Tad T. Brunyé
Department of Psychology Faculty Scholarship and Creative Works
Unilateral hand clenching increases neuronal activity in the frontal lobe of the contralateral hemisphere. Such hand clenching is also associated with increased experiencing a given hemisphere’s “mode of processing.” Together, these findings suggest that unilateral hand clenching can be used to test hypotheses concerning the specializations of the cerebral hemispheres during memory encoding and retrieval. We investigated this possibility by testing the effects of a unilateral hand clenching on episodic memory. The hemispheric Encoding/Retrieval Asymmetry (HERA) model proposes left prefrontal regions are associated with encoding, and right prefrontal regions with retrieval, of episodic memories. It was hypothesized that right-hand clenching …
Research Brief: "Cognitive Behavioral Treatment For Post-Traumatic Nightmares: An Investigation Of Predictors Of Dropout And Outcome",
2013
Syracuse University
Research Brief: "Cognitive Behavioral Treatment For Post-Traumatic Nightmares: An Investigation Of Predictors Of Dropout And Outcome", Institute For Veterans And Military Families At Syracuse University
Institute for Veterans and Military Families
This brief is about the cognitive behavior treatment outcomes and drop outs of Vietnam veterans with PTSD who experience nightmares. In policy and practice, various socialization strategies should be implemented by clinics based on veterans' levels of traumatic history, and veterans' families should work to create a positive view of therapy; policymakers should provide support for these therapies and the training of clinicians to provide them. Suggestions for future research include having a more generalizable population in the study, examining the impact of the study's exclusion criteria, and the impact of psychotropic medicines on treatment outcome.
Unconscious Processing Of Unattended Features In Human Visual Cortex,
2013
CUNY Bernard M Baruch College
Unconscious Processing Of Unattended Features In Human Visual Cortex, Tatiana Aloi Emmanouil, Philip Burton, Tony Ro
Publications and Research
Unconscious processing has been convincingly demonstrated for task-relevant feature dimensions. However, it is possible that the visual system is capable of more complex unconscious operations, extracting visual features even when they are unattended and task irrelevant. In the current study, we addressed this question by measuring unconscious priming using a task in which human participants attended to a target object's shape while ignoring its color. We measured both behavioral priming effects and priming-related fMRI activations from primes that were unconsciously presented using metacontrast masking. The results showed faster RTs and decreases in fMRI activation only when the primes were identical …
You, Your Neurons, And Free Will: Concerns About Reductionism And The Popularization Of Cognitive Science,
2013
Andrews University
You, Your Neurons, And Free Will: Concerns About Reductionism And The Popularization Of Cognitive Science, Karl G. D. Bailey
Faculty Publications
No abstract provided.
Changes In Sleep Architecture And Cognition With Age And Psychosocial Stress: A Study In Fischer 344 Rats,
2013
University of Kentucky
Changes In Sleep Architecture And Cognition With Age And Psychosocial Stress: A Study In Fischer 344 Rats, Heather M. Buechel
Theses and Dissertations--Pharmacology and Nutritional Sciences
Changes in both sleep architecture and cognition are common with age. Typically these changes have a negative connotation: sleep fragmentation, insomnia, and deep sleep loss as well as forgetfulness, lack of focus, and even dementia and Alzheimer’s disease. Research has shown that psychosocial stressors, such as isolation from family and friends or loss of a loved one can also have significant negative effects on sleep architecture and cognitive capabilities. This leaves the elderly in a particularly vulnerable situation: suffering from cognitive decline and sleep dysregulation already, and more likely to respond negatively to psychosocial stressors. Taking all of these factors …
Prospective, Open-Label Trial Measuring Satisfaction And Convenience Of Two Formulations Of Lamotrigine In Subjects With Mood Disorders,
2013
Case Western Reserve University
Prospective, Open-Label Trial Measuring Satisfaction And Convenience Of Two Formulations Of Lamotrigine In Subjects With Mood Disorders, Martha Sajatovic
Faculty Scholarship
Background: Lamotrigine is an anticonvulsant drug indicated for the maintenance treatment of bipolar I disorder and for various types of epilepsy. An orally disintegrating tablet (ODT) of lamotrigine was developed to provide a formulation option that might increase patient convenience and satisfaction. Methods: Subjects with mood disorders who reported difficulty swallowing currently prescribed lamotrigine immediate-release medication (baseline) were enrolled and treated with lamotrigine ODT for three weeks (end of treatment). Subject satisfaction and convenience were measured using the Treatment Satisfaction Questionnaire for Medication (TSQM). Also measured were global psychopathology using the Clinical Global Impression severity index (CGI-S) and depressive symptoms …
Doxorubicin-Induced, Tnf-Α-Mediated Brain Oxidative Stress, Neurochemical Alterations, And Cognitive Decline: Insights Into Mechanisms Of Chemotherapy Induced Cognitive Impairment And Its Prevention,
2013
University of Kentucky
Doxorubicin-Induced, Tnf-Α-Mediated Brain Oxidative Stress, Neurochemical Alterations, And Cognitive Decline: Insights Into Mechanisms Of Chemotherapy Induced Cognitive Impairment And Its Prevention, Jeriel T. Keeney
Theses and Dissertations--Chemistry
The works presented in this dissertation provide insights into the mechanisms of chemotherapy-induced cognitive impairment (CICI or “ChemoBrain”) and take steps toward outlining a preventive strategy. CICI is now widely recognized as a complication of cancer chemotherapy experienced by a large percentage of cancer survivors. Approximately fifty percent of existing FDA-approved anti-cancer drugs generate reactive oxygen species (ROS). Doxorubicin (Dox), a prototypical ROS-generating chemotherapeutic agent, produces the reactive superoxide radical anion (O2-•) in vivo. Dox treatment results in oxidation of plasma proteins, including ApoA-I, leading to TNF-α-mediated oxidative stress in plasma and brain. TNF-α elevation in brain …
Biological Motion And Gender Recognition: Visual Fixation On The Inversion Effect,
2012
Belmont University
Biological Motion And Gender Recognition: Visual Fixation On The Inversion Effect, Andrey P. Borisyuk, Rachel J. Garland, Alysse M. Feldman, Abigail R. Marchese
Science University Research Symposium (SURS)
Gender recognition of point-light animations replicated an inversion effect. Participants identified the gender of thirty-two (half upright and half inverted, half male and half female) moving point-light human figures. Male figures were more accurately recognized in upright animations whereas female figures were more accurately recognized in inverted animations. Eye gaze of both genders was identical in both the upright animations (predominantly waist and shoulders) and inverted animations (predominantly waist but more distributed across body parts).
Process And Domain Specificity In Regions Engaged For Face Processing: An Fmri Study Of Perceptual Differentiation,
2012
University of Kentucky
Process And Domain Specificity In Regions Engaged For Face Processing: An Fmri Study Of Perceptual Differentiation, Heather R. Collins, Xun Zhu, Ramesh S. Bhatt, Jonathan D. Clark, Jane E. Joseph
Psychology Faculty Publications
The degree to which face-specific brain regions are specialized for different kinds of perceptual processing is debated. This study parametrically varied demands on featural, first-order configural, or second-order configural processing of faces and houses in a perceptual matching task to determine the extent to which the process of perceptual differentiation was selective for faces regardless of processing type (domain-specific account), specialized for specific types of perceptual processing regardless of category (process-specific account), engaged in category-optimized processing (i.e., configural face processing or featural house processing), or reflected generalized perceptual differentiation (i.e., differentiation that crosses category and processing type boundaries). ROIs were …
Cocaine-Induced Reinstatement Of A Conditioned Place Preference In Developing Rats: Involvement Of The D2 Receptor,
2012
University of South Florida
Cocaine-Induced Reinstatement Of A Conditioned Place Preference In Developing Rats: Involvement Of The D2 Receptor, Kimberly A. Badanich, Cheryl L. Kirstein
Psychology Faculty Publications
Reinstatement of conditioned place preferences have been used to investigate physiological mechanisms mediating drug-seeking behavior in adolescent and adult rodents; however, it is still unclear how psychostimulant exposure during adolescence affects neuron communication and whether these changes would elicit enhanced drug-seeking behavior later in adulthood. The present study determined whether the effects of intra-ventral tegmental area (VTA) or intra-nucleus accumbens septi (NAcc) dopamine (DA) D2 receptor antagonist infusions would block (or potentiate) cocaine-induced reinstatement of conditioned place preferences. Adolescent rats (postnatal day (PND 28–39)) were trained to express a cocaine place preference. The involvement of D2 receptors on cocaine-induced reinstatement …
