Preparation Of Cellulose Nanocrystals From The Shells Of Camellia Oleifera Abel And Their Effect On The Stability Of Camellia Oil Pickering Emulsions,
2026
School of Food Science and Bioengineering , Changsha University of Science and Technology , Changsha , Hunan 410114 , China;State Key Laboratory of Woody Oil Resources Utilization , Hunan Academy of Forestry , Changsha , Hunan 410004 , China
Preparation Of Cellulose Nanocrystals From The Shells Of Camellia Oleifera Abel And Their Effect On The Stability Of Camellia Oil Pickering Emulsions, Jin Sheng, Xie Shuting, Xiao Zhihong, Li Changzhu, Wang Jianhui
Food and Machinery
[Objective] To prepare cellulose nanocrystals from the shells of Camellia oleifera Abel (SCOA–CNCs) for stabilizing camellia oil Pickering emulsions, and to investigate the storage stability and environmental stability of the resulting emulsions. [Methods] Cellulose is extracted from SCOA through bleaching and alkali treatment, and SCOA–CNCs are prepared by sulfuric acid hydrolysis and characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD). The SCOA–CNCs are employed to stabilize camellia oil Pickering emulsions; the effects of the oil-to-water ratio and particle concentration on the emulsions are examined, and the stability of the emulsions under different environmental …
Advances In The Application Of Electroencephalography In Food Sensory Science,
2026
School of Food Science and Bioengineering , Changsha University of Science and Technology , Changsha , Hunan 410114 , China;Hunan Provincial Engineering Technology Research Center of Prepared Dishes , Changsha , Hunan 410114 , China
Advances In The Application Of Electroencephalography In Food Sensory Science, Li Wenbin, Hou Xiaoyi, Deng Na, Leng Tuo, Fu Haohua, Wang Jianhui
Food and Machinery
Traditional sensory evaluation of food is affected by subjectivity and other factors, resulting in significant limitations. Electroencephalography (EEG), owing to its advantages of high temporal resolution, non-invasiveness, and real-time dynamic monitoring, offers an objective neurophysiological perspective and analytical approach to address this issue, effectively advancing food science research from subjective descriptions to objective neural decoding. This paper systematically reviews the applications of EEG in food flavor recognition and prediction, objective evaluation of food quality, and analysis of food nutrition and consumer behavior. In light of the current state of technological development, it is proposed that multimodal technology integration and machine …
Research Progress On Tubular Chain Conveyors And Their Applications In The Grain, Oil And Food Industry,
2026
COFCO Engineering & Technology (Zhengzhou ) Co., Ltd., Zhengzhou , Henan 450001 , China
Research Progress On Tubular Chain Conveyors And Their Applications In The Grain, Oil And Food Industry, Wu Weiwei, Xia Chaoyong, Sui Sai
Food and Machinery
Tubular chain conveyors have become core equipment in modern bulk material handling by virtue of their significant advantages, including highly efficient conveying, fully enclosed operation, and three-dimensional flexible spatial layout. This paper systematically reviews the current status and progress of research on tubular chain conveyors both domestically and internationally, and provides an in-depth analysis of their technological evolution, core theoretical framework, and industrial adaptability. Emphasis is placed on reviewing their engineering applications in the grain, oil, and food industry. In view of the remaining deficiencies in current research concerning adaptability to extreme operating conditions, multi-physics coupling mechanism modeling, large-scale implementation …
Data For Post-Retail Application Of Chitosan Coating And Uv-C Irradiation: Effects On Strawberry Shelf Life, Microbial Quality, And Consumer Acceptance, Jonathan Kershaw
ScholarsArchive Data
Food waste is a global issue with significant environmental, economic, and human health impacts. The largest share of household and retail food waste comes from fresh produce, much of which is still edible at the time of disposal. While previous work has investigated shelf-life extension technologies applied on freshly harvested produce, almost no studies have investigated the efficacy of these treatments when applied to post-retail produce. This study investigated the effect of UV-C exposure and chitosan coating on the quality, microbial load, and visual acceptance of post-retail strawberries. Strawberries were assigned to low dose UV-C, chitosan dip, or one of …
Advanced Hybrid-Green Ultrasound–Infrared–Microwave Trifolium Repens Essential Oil Isolation With Multi-Target Ethnomedicine Bioactivity Against Neuropathy, Inflammation And Multidrug-Resistant Infection,
2026
Department of Pharmaceutical Sciences, Faculty of Pharmacy, Beirut Arab University, Beirut, Lebanon.
Advanced Hybrid-Green Ultrasound–Infrared–Microwave Trifolium Repens Essential Oil Isolation With Multi-Target Ethnomedicine Bioactivity Against Neuropathy, Inflammation And Multidrug-Resistant Infection, Sara Al Ayoubi, Ibrahim Abdelwahab, Maha Aboul-Ela, Abdalla El- Lakany, Karim Raafat
Journal of Food and Drug Analysis
Trifolium repens (white clover) is rich in bioactive volatiles with therapeutic potential. This study developed an advanced hybrid ultrasound–infrared–microwave hydro-distillation (UIMHD) method for efficient essential oil (EO) isolation and investigated its active sesquiterpene, pseudoionone, for multi-mechanistic neuroprotection in diabetic neuropathy (DN). The optimized UIMHD system synergistically combined ultrasound cavitation, infrared heating, and microwave hydro-distillation, enhancing yield and reducing time versus conventional extraction. Gas chromatography–mass spectrometry (GC–MS) profiling identified pseudoionone as the dominant constituent. Pharmacological evaluations were performed in alloxan-induced diabetic mice to assess antidiabetic, anti-inflammatory, neuroprotective, and anticonvulsant activities. Cytokine modulation (TNF-α, IL-6, IL-10), oxidative stress markers (CAT, GSH, TBARS), …
Can Semaglutide Influence Tumor Biomarkers? Insight From A Clinical Case,
2026
Division of Clinical Pharmacology and Toxicology, Institute of Pharmacological Sciences of Southern Switzerland, Ente Ospedaliero Cantonale, Lugano, Switzerland
Can Semaglutide Influence Tumor Biomarkers? Insight From A Clinical Case, Alice Schianchi, Fabio Mauri, Christian Polli
Journal of Food and Drug Analysis
To our knowledge, this is the first case reported in literature, regarding an increase in tumoral biomarkers during a treatment with Semaglutide. A 61-year-old patient was referred to our gynecological consultation due to suspected adnexal cysts following an MRI performed for a functional defecation disorder. The patient was on Semaglutide treatment. Gynecological examination and transvaginal ultrasound were normal, with no evidence of adnexal cysts. Tumor biomarker testing revealed a significant increase in CA 19-9 and a mild elevation in CA-125. In an asymptomatic patient, these findings raised suspicion of a possible neoplastic origin involving the pancreas or biliary tract. However, …
Evaluating The Efficacy Of I-Fiber Pearl On Reducing Body Fat Accumulation In Obese Females: A Randomized, Double-Blind, And Placebo-Controlled Trial,
2026
Department of Nutrition, Chung Shan Medical University, Taichung, Taiwan
Evaluating The Efficacy Of I-Fiber Pearl On Reducing Body Fat Accumulation In Obese Females: A Randomized, Double-Blind, And Placebo-Controlled Trial, Hung-Hsuan Kuo, Chia-Chun Chen, Ching-Chang Cho, Chun-Tse Tsai, Shiuan-Chih Chen, Chin-Lin Hsu
Journal of Food and Drug Analysis
Obesity is a growing public health challenge worldwide, strongly linked to metabolic syndrome, type 2 diabetes, and cardiovascular disease. Inulin, a soluble, fermentable fiber derived mainly from Jerusalem artichoke and chicory, has been reported to improve weight management and metabolic health. This randomized, double-blind, placebo-controlled trial evaluated the effects of inulin-enriched tapioca pearls (I-fiber pearl) on body composition and lipid parameters in obese women. Methods: Fifty women (BMI ≥ 27 or waist > 80 cm; age 20–50 years) were randomized to receive either I-fiber pearl or placebo (2 packs/day, 100 g/pack) for 12 weeks. Anthropometric indices, body composition, and blood biochemistry …
Spatial Distribution: Effect Of Oxygen Availability On Gut Microbiota Adhesion And Colonization,
2026
Key Laboratory of Ecological Restoration of Regional Contaminated Environment, Ministry of Education, College of Environment, Shenyang University, Shenyang 110044, China
Spatial Distribution: Effect Of Oxygen Availability On Gut Microbiota Adhesion And Colonization, Ruixue Ding, Xiaotong Sun, Yinan Wang, Binbin Tu, Yue Liang, Qi Lin, Fuqiang Zhao
Journal of Food and Drug Analysis
The gut microbiota plays a crucial role in host digestion and immune regulation; however, most existing research relies on fecal sampling, leaving uncertainty regarding whether fecal microbiota can accurately reflect the symbiotic microbial components at distinct gut sites. To address this gap, this study employed 16S rRNA gene sequencing to systematically analyze the microbial composition of three spatial compartments in the rat colon: luminal contents, mucus layer, and epithelial tissue. The results revealed notable differences in microbial communities across the three compartments. The luminal contents, which were closely associated with the fecal microbiota, exhibited high microbial abundance, encompassing gram-positive bacteria, …
Novel Oral Delivery System Using Modified Inulin For Enhanced Liver Cancer Therapy,
2026
School of Pharmacy, National Defense Medical University, Taipei, Taiwan, ROC.
Novel Oral Delivery System Using Modified Inulin For Enhanced Liver Cancer Therapy, Sung-Ling Tang, Yu-Ju Lai, Wei-Cheng Lin, Meng-Yi Bai, Yu-Chi Wang
Journal of Food and Drug Analysis
Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related deaths worldwide. Although advanced oral anticancer drugs, such as sorafenib and lenvatinib, are available for treating HCC, their effectiveness is limited by significant side effects and the requirement for optimal liver function, restricting their broader use. Furthermore, these drugs cannot be used in combination, leading to suboptimal treatment outcomes. This study introduces a novel therapeutic approach by repurposing two existing drugs, niclosamide and disulfiram, as a combination therapy to treat HCC. Despite their known anticancer properties, these drugs face challenges such as high lipophilicity and a significant first-pass effect, resulting in …
Effect Of Cosmetic Whitening Ingredients’ Lipophilicity On Melanocyte Cytotoxicity: A Systematic Review,
2026
Department of Pharmacy, School of Health Care Professions, University of San Carlos, Nasipit, Talamban, Cebu, 6000, The Philippines
Effect Of Cosmetic Whitening Ingredients’ Lipophilicity On Melanocyte Cytotoxicity: A Systematic Review, Lord Sam B. Liston, Zach Uriel Cabije, Enrico John Belleza, Catherine Ortega, Mark Niño Melgo, Vanbeth Camson, Sabrina Dahlizar, Pajaree Sakdiset, Gea Abigail Ecoy, Gerard Lee See, Florencio Jr. Arce
Journal of Food and Drug Analysis
Tyrosinase is an enzyme involved in the early stages of melanin synthesis. Melanin, which gives skin its pigment, is the most targeted molecule in the development of skin-whitening cosmetic products. Consequential risks of chemically induced skin diseases are associated with the usage of skin-whitening products that contain tyrosinase-inhibiting compounds. Currently, products containing tyrosinase inhibitors on the market lack collective analysis of their toxicity on melanocytes. Moreover, national regulatory agencies (e.g., FDA) place the burden of ensuring the safety of whitening products on manufacturers, risking bias and selective reporting. In fact, the ASEAN Cosmetic Directive does not include more than half …
The Protective Potential Of Intestinal Bifidobacterium-Derived Extracellular Vesicles With Unique Lipid Composition Against Blue Light-Induced Damage In Retinal Cells,
2026
Department of Food Safety/Hygiene and Risk Management, College of Medicine, National Cheng Kung University, Tainan, Taiwan
The Protective Potential Of Intestinal Bifidobacterium-Derived Extracellular Vesicles With Unique Lipid Composition Against Blue Light-Induced Damage In Retinal Cells, Wei-Hsuan Hsu, Pin-Hsuan Su, Hao-Yuan Chien, Tzu-Ming Pan, Bao-Hong Lee
Journal of Food and Drug Analysis
Bifidobacterium longum is a probiotic that resides in the intestine, and extracellular vesicles (EVs) released by microorganisms have garnered attention in recent years for their role in regulating host health. This study found that triacylglycerol, cholesteryl esters, and free fatty acid (18:0 and 16:0) are primarily composed of lipids in B. longum-derived EVs by lipidomics assay. Such lipid composition facilitates the entry of EVs into ARPE-19 cells and protects the cells from oxidative death induced by blue light exposure. Transcriptomic analysis revealed that treatment with B. longum-derived EVs can regulate phosphoinositide 3-kinase and mTOR, thereby enhancing the survival …
Systematic Verification Of Saliva-Based Biosignatures For Oral Cancer Via Targeted Metabolomics,
2026
Molecular Medicine Research Center, College of Medicine, Chang Gung University, Taoyuan, Taiwan
Systematic Verification Of Saliva-Based Biosignatures For Oral Cancer Via Targeted Metabolomics, Ya-Ju Hsieh, Yu Chang, Chi Yang, Nai Hsuan Teng, Jau-Song Yu, Kai-Ping Chang, Wen-Chen Chen, Lichieh Julie Chu, Yi-Ting Chen
Journal of Food and Drug Analysis
Oral squamous cell carcinoma (OSCC) remains a major global health challenge, and early detection is essential for improving patient outcomes. To identify reliable salivary biomarkers, we performed a targeted metabolomics study using 13C2/12C2-dansylation, integrating candidate metabolites from published OSCC metabolomics datasets and systematically verifying them through LC-MRM-MS. A panel of 26 metabolites was quantified in saliva samples from 299 subjects, including healthy controls (n = 98), oral potentially malignant disorders (OPMD I, n = 50; OPMD II, n = 53), and OSCC patients (n = 98). Among these, cadaverine, N-acetylcadaverine, choline, glycine, and …
Phthalate Exposure And Lipid Disruption In Taiwanese Children: Insights From Serum Lipidomic Approach,
2026
Institute of Environmental and Occupational Health Sciences, College of Public Health, National Taiwan University, Taipei, Taiwan
Phthalate Exposure And Lipid Disruption In Taiwanese Children: Insights From Serum Lipidomic Approach, Tzu-Hsin Yen, Wei-Chen Tseng, Sheng-Han Lee, Zhi-Yi Du, Wan-Yu Lin, Mei-Huei Chen, Ching-Chun Lin, Ching-Chun Lin, Hui-Ju Wen, Hao-Jan Liang, Yue-Leon Guo, Pau-Chung Chen, Ching-Yu Lin
Journal of Food and Drug Analysis
Phthalates are ubiquitous environmental contaminants that raise particular concern for children, who generally experience higher exposure levels and are more susceptible to environmental pollutants. To understand potential molecular mechanisms, we conducted a cross-sectional study of 256 Taiwanese children aged 8–10 years from two population-based cohorts: the Taiwan Birth Panel Study and the Taiwan Early-Life Cohort. Serum phosphocholine-containing lipids were profiled by liquid chromatography coupled with triple quadrupole mass spectrometry and associated with urinary levels of 12 phthalate metabolites. Multiple linear regression models, adjusted for demographic and socioeconomic factors, revealed that mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), an oxidative metabolite of di(2-ethylhexyl) phthalate (DEHP), …
Applications Of Nuclear Magnetic Resonance Spectroscopy In Pediatric Clinical Metabolomics: From Research To Future Perspectives,
2026
Division of Pediatric Pulmonology, Department of Pediatrics, Chang Gung Memorial Hospital at Linkou, and Chang Gung University, Taoyuan, Taiwan
Applications Of Nuclear Magnetic Resonance Spectroscopy In Pediatric Clinical Metabolomics: From Research To Future Perspectives, Chieh-Ni Kuo, Meng-Han Chiang, Hsien-Ju Lee, Yu-Ying Yu, Eric Yi-Liang Shen, Chih-Yung Chiu
Journal of Food and Drug Analysis
Metabolomics studies small-molecule metabolites to provide insights into health and disease, supporting early diagnosis and personalized medicine. Advances in mass spectrometry and nuclear magnetic resonance (NMR) have expanded its use in metabolic, cancer, and cardiovascular diseases. In pediatrics, high-resolution NMR metabolomics has been instrumental in identifying age-related metabolic changes during early childhood and their associations with growth, nutrition, and disease risk. However, a comprehensive review of its clinical applications and future potential remains limited. This review highlights how utilizing specific NMR pulse sequences, such as CPMG and NOESY, allows for precise and non-destructive metabolic profiling of diverse biofluids, supported by …
The Evolution Of Desi-Msi: A Comprehensive Look At Preprocessing And Quantification Strategies For Metabolomics,
2026
Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan City, Taiwan
The Evolution Of Desi-Msi: A Comprehensive Look At Preprocessing And Quantification Strategies For Metabolomics, Cheng-Hung Yang, Hung-Yao Ho, Chen-Yu Chang, Mei-Ling Cheng
Journal of Food and Drug Analysis
Mass spectrometry imaging (MSI) has become an indispensable tool in metabolomics for visualizing the spatial distribution of biomolecules within tissues. Due to its direct, ambient analysis capability, desorption electrospray ionization (DESI-MSI) has evolved from a rapid screening tool into a precise and reliable quantitative platform. We delve into its technical principles and particularly review the criticality of sample preprocessing, highlighting the paradigm shift from a "no-preprocessing" approach to one of "optimized preprocessing." The paper details how factors like sample preservation, choice of embedding agents, washing, drying, and on-tissue chemical derivatization all impact data quality. We also discuss how the addition …
Advanced Technologies Of Single-Cell Metabolomics Unveiling Cellular Metabolic Heterogeneity For Biological And Biomedical Research,
2026
Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan.
Advanced Technologies Of Single-Cell Metabolomics Unveiling Cellular Metabolic Heterogeneity For Biological And Biomedical Research, Shang-Che Kuo, Ting-Wei Tsao, I-Fan Wang, Ying-Lan Chen
Journal of Food and Drug Analysis
Metabolomics provides direct insights into cellular physiology, yet it faces greater analytical challenges compared to genomics and transcriptomics due to the chemical diversity, instability, and environmental sensitivity of metabolites. Conventional bulk metabolomics averages signals across cell populations, thereby masking cellular heterogeneity critical for understanding disease mechanisms. Recent breakthroughs in single-cell metabolomics (SCM), driven by advances in mass spectrometry, microfluidics, isotope tracing, and spatial omics, have enabled the detection of metabolic diversity at unprecedented resolution. SCM has uncovered cell-type-specific biomarkers, revealed metabolic reprogramming in cancer and immunity and revealed disease progression. These studies highlight SCM’s transformative potential in biomarker discovery, clinical …
Metabolomics Of Per- And Polyfluoroalkyl Substances (Pfas) Exposure: Advances In Lc-Ms Technology And Applications,
2026
Graduate Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan
Metabolomics Of Per- And Polyfluoroalkyl Substances (Pfas) Exposure: Advances In Lc-Ms Technology And Applications, Yu-Meng Wang, Pei-Chen Lin, Yu-Da Zheng, Pin-Shiuan Wu, Kuo-Tai Hua, Sung-Fang Chen
Journal of Food and Drug Analysis
Per- and polyfluoroalkyl substances (PFAS) are a class of synthetic chemicals known for their high stability and bioaccumulation potential, leading to their widespread presence in the environment and human tissues. Exposure to PFAS has been associated with significant health concerns, including neurotoxicity, hepatotoxicity, and metabolic disturbances. Liquid chromatography–mass spectrometry (LC-MS) based metabolomics has emerged as a powerful and central tool for PFAS research, enabling the comprehensive analysis of metabolic changes induced by exposure. This review provides a critical summary of the applications of LC-MS metabolomics in both clinical studies and various experimental models, including in vivo models (mice) and in …
Recent Advances In Sustainable Production Of Enriched Chicken Eggs: A Mini Review,
2026
Department of Poultry Production, Faculty of Agriculture, Alexandria University, Alexandria, Egypt
Recent Advances In Sustainable Production Of Enriched Chicken Eggs: A Mini Review, Karim El-Sabrout, Ayman Abd El-Aziz
Jurnal Ilmu Ternak Universitas Padjadjaran
Enriched or “designer” chicken eggs have emerged as an important category of functional foods aimed at improving human nutrition through dietary manipulation of laying hens. This mini-review summarizes recent advances in egg enrichment strategies, focusing on omega-3 fatty acids, vitamins, minerals, and antioxidant compounds. Omega-3 enrichment remains the most widely adopted approach, achieved through supplementation with flaxseed, fish oil, or microalgae, resulting in significant increases in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in egg yolk. Multi-nutrient enrichment, including selenium, vitamin E, and carotenoids, has also gained attention due to its potential in enhancing antioxidant capacity and health of hens …
Effect Of Dietary Onion Peel Powder (Allium Cepa L.) As A Feed Additive On Production Performance In Broiler,
2026
Faculty of Animal Science, Universitas Brawijaya, Malang 65145, Indonesia
Effect Of Dietary Onion Peel Powder (Allium Cepa L.) As A Feed Additive On Production Performance In Broiler, Della Ariesba Putri Dulia, Edhy Sudjarwo, Osfar Sjofjan
Jurnal Ilmu Ternak Universitas Padjadjaran
This study aims to evaluate the use of onion peel powder (Allium cepa L) as a feed additive on feed intake, weight gain, Feed Conversion Ratio (FCR), Production Index, and Income Over Feed Cost (IOFC) in broilers. A total of 144 Lohmann strain broiler (unsexed) were treated from 1 to 35 days of age. There were 6 treatments with 4 replicates, consisting of 24 experimental cages, each filled 6 broilers. The experimental design used completely randomized design (CRD). The treatment groups were as follows: basal feed without antibiotics (P0-), basal feed + 0.1% antibiotics (zinc bacitracin) (P0+), basal feed + …
Effect Of Gowok (Syzygium Polycephalum) Fortification On The Physical Properties And Color Of Goat Milk Yogurt,
2026
Faculty of Animal Science, Jenderal Soedirman University, Indonesia
Effect Of Gowok (Syzygium Polycephalum) Fortification On The Physical Properties And Color Of Goat Milk Yogurt, Siti Rahmawati Zulaikhah, Triana Setyawardani, Juni Sumarmono
Jurnal Ilmu Ternak Universitas Padjadjaran
This study aimed to determine the effect of adding parts of gowok fruit (Syzygium polycephalum) on the physical properties of goat’s milk yogurt. A completely randomized design was applied with treatments consisting of fruit parts (rind, flesh of fruit, and whole seedless fruit) and addition levels (1, 2, and 3%) with three replications. Data were analyzed using analysis of variance followed by Duncan’s multiple range test (DMRT). The results showed that gowok addition had a significant effect (P<0.05) on viscosity, syneresis, and color parameters, but no significant effect (P>0.05) on firmness and work of penetration. Yogurt viscosity ranged from 349.33 to 825 mPa·s and decreased with increasing gowok levels, while …0.05)>
