Physical Sciences and Mathematics Commons^™

Aspects Of The Equivalence Between The FΜ And C Vμ Terms In Lorentz-Violating Quantum Field Theory, Sapan Karki, Brett David Altschul

Faculty Publications

It is known that in Lorentz-violating effective field theory, there is a classical equivalence between certain coefficients (c and f), in spite of the fact that the operators of the two types of coefficients described appear to have opposite behaviors under CPT. This paper is a continuation of previous work extending this equivalence to the quantum level: generalizing the explicit spinorial point transformations that interconvert the c and f terms; demonstrating that the transformations do not give rise to any additional anomaly terms as the quantum level; and giving explicit prescriptions for modifying the C, P, and T operators in …

On A Prior Based On The Wasserstein Information Matrix, Wuchen Li, F. J. Rubio

Faculty Publications

We introduce a prior for the parameters of univariate continuous distributions, based on the Wasserstein information matrix, which is invariant under reparameterisations. We discuss the links between the proposed prior with information geometry. We present sufficient conditions for the propriety of the posterior distribution for general classes of models. We present a simulation study that shows that the induced posteriors have good frequentist properties.

Probing Free Nucleons With (Anti)Neutrinos, Roberto Petti

Faculty Publications

We discuss a method to study free protons and neutrons using ν(⊽)-hydrogen (H) Charged Current (CC) inelastic interactions, together with various precision tests of the isospin (charge) symmetry using ν and ⊽ CC interactions on both H and nuclear targets. Probing free nucleons with (anti)neutrinos provides information about their partonic structure, as well as a crucial input for the modeling of ν(⊽)-nucleus (A) interactions. Such measurements concurrently represent a valuable tool to address the main limitations of accelerator-based neutrino scattering experiments on nuclear targets, originating from the combined effect of the unknown (anti)neutrino energy and of the …

Antibody Prevalence And Risk Factors Associated With Rickettsia Spp. In A Pediatric Cohort: Sfgr Remains Underdiagnosed And Underreported In El Salvador, Kyndall C. Dye-Braumuller, Marvin Stanley Rodríguez Aquino, Kia Zellars, Hanna Waltz, Madeleine Meyer, Lídua Gual-Gonzalez, Stella C.W. Self, Mufaro Kanyangarara, Melissa Nolan Ph.D., Mph

Faculty Publications

Spotted fever group rickettsioses (SFGR) are caused by a group of tick-borne pathogens that are increasing in incidence globally. These diseases are typically underreported and undiagnosed in low- and middle-income countries, and thus, have been classified as neglected bacterial pathogens. Countries with high poverty, low human development index score, and limited health infrastructure—like El Salvador in Central America—lack necessary surveillance for SFGR and other tick-borne pathogens. This paucity of baseline SFGR infection prevalence leaves vulnerable populations at risk of misdiagnosis. Further, tick-borne disease burdens in El Salvador are severely limited. To lay the foundation for tick-borne disease epidemiology in El …

Influence Of Surface Water Displacement On Solvation Thermodynamics, Mia Kim

Journal of the South Carolina Academy of Science

No abstract provided.

Process Evaluation Methods And Results From The Health In Pregnancy And Postpartum (Hipp) Randomized Controlled Trial, Sarah Wilcox Phd, Alicia A. Dahl, Alycia K. Boutté, Jihong Liu Sc.D., Kelsey Day, Gabrielle Turner-Mcgrievy Ph.D., Rd, Ellen Wingard

Faculty Publications

Background

Excessive gestational weight gain has increased over time and is resistant to intervention, especially in women living with overweight or obesity. This study described the process evaluation methods and findings from a behavioral lifestyle intervention for African American and white women living with overweight and obesity that spanned pregnancy (≤ 16 weeks gestation) through 6 months postpartum.

Methods

The Health in Pregnancy and Postpartum (HIPP) study tested a theory-based behavioral intervention (vs. standard care) to help women (N = 219; 44% African American, 29.1 ± 4.8 years) living with overweight or obesity meet weight gain guidelines in pregnancy and …

Higher Adherence To A Mediterranean Diet Is Associated With Improved Insulin Sensitivity And Selected Markers Of Inflammation In Individuals Who Are Overweight And Obese Without Diabetes, Surbhi Sood, Jack Feehan, Catherine Itsiopoulos, Kirsty Wilson, Magdalena Plebanski, David Scott, James Hébert Scd, Nitin Shivappa Mbbs, Mph, Ph.D., Aya Mousa, Elena S. George, Barbora De Courten

Faculty Publications

Insulin resistance (IR) and chronic low-grade inflammation are risk factors for chronic diseases including type 2 diabetes (T2D) and cardiovascular disease. This study aimed to investigate two dietary indices: Mediterranean Diet Score (MDS) and Dietary Inflammatory Index (DII®), and their associations with direct measures of glucose metabolism and adiposity, and biochemical measures including lipids, cytokines and adipokines in overweight/obese adults. This cross-sectional study included 65 participants (males = 63%; age 31.3 ± 8.5 years). Dietary intake via 3-day food diaries was used to measure adherence to MDS (0–45 points); higher scores indicating adherence. Energy-adjusted DII (E-DII) scores were calculated with …

The Impact Of Meal Dietary Inflammatory Index On Exercise-Induced Changes In Airway Inflammation In Adults With Asthma, Katrina P. Mcdiarmid, Lisa G. Wood, John W. Upham, Lesley K. Macdonald-Wicks, Nitin Shivappa Mbbs, Mph, Ph.D., James R. Hébert Scd, Hayley A. Scott

Faculty Publications

Research suggests exercise may reduce eosinophilic airway inflammation in adults with asthma. The Dietary Inflammatory Index (DII®) quantifies the inflammatory potential of the diet and has been associated with asthma outcomes. This study aimed to determine whether the DII of a meal consumed either before or after exercise influences exercise-induced changes in airway inflammation. A total of 56 adults with asthma were randomised to (1) 30–45 min moderate–vigorous exercise, or (2) a control group. Participants consumed self-selected meals, two hours pre- and two hours post-intervention. Energy-adjusted DII (E-DIITM) was determined for each meal, with meals then characterised as “anti-inflammatory” or …

Tutorial: Neuro-Symbolic Ai For Mental Healthcare, Kaushik Roy, Usha Lokala, Manas Gaur, Amit Sheth

Publications

Artificial Intelligence (AI) systems for mental healthcare (MHCare) have been ever-growing after realizing the importance of early interventions for patients with chronic mental health (MH) conditions. Social media (SocMedia) emerged as the go-to platform for supporting patients seeking MHCare. The creation of peer-support groups without social stigma has resulted in patients transitioning from clinical settings to SocMedia supported interactions for quick help. Researchers started exploring SocMedia content in search of cues that showcase correlation or causation between different MH conditions to design better interventional strategies. User-level Classification-based AI systems were designed to leverage diverse SocMedia data from various MH conditions, …

2022 Scas Annual Meeting Program And Bulletin

Journal of the South Carolina Academy of Science

No abstract provided.

Environmental Bacteriophage Detection On Coastal Carolina University Campus, Madison Gentilo, Hailey Oldfield, Gavin Ockert, Paul E. Richardson

Journal of the South Carolina Academy of Science

Bacteriophages are viruses that infect bacteria. These viruses are found ubiquitously in the environment and are more abundant than any living organism on Earth, including bacteria. Eleven sites are designated for weekly sample collection on the campus of Coastal Carolina University. Water samples are filtered and amplified using strains of E. coli B and E. coli K12 to allow potential coliphages in the sample to proliferate to detectable levels. Plaque assays are used as a microbial screen for the presence of bacteriophage. Samples that test positively using the microbial test are analyzed through a molecular test using PCR to identify …

3,6-Dimethoxyxanthone From 2,2’,4,4’- Tetrahydroxy-Benzophenone Via Microwave-Assisted Annulation, Sarah E. Knisely, Faith R. Rosario, Salem F. Gebeyehu, Paige E. Heiple, Robert E. Lee Sr

Journal of the South Carolina Academy of Science

Xanthones are tricyclic aromatic compounds that have multiple pharmacological uses due to their anti-tumor, antioxidant, anti-inflammatory, anti-bacterial, and potentially chemopreventive properties. The target of this research was to optimize a two-step synthesis of 3,6-dimethoxyxanthone (3) from 2,2’,4,4’-tetrahydroxy-benzophenone (1) via microwave-assisted (200 °C, 30-40 min., 150 W) sodium acetate-catalyzed annulation. The product, 3,6-dihydroxyxanthone (2), was then methylated to (3) using dimethyl sulfate (DMS) and sodium carbonate in acetone at reflux. The product yields were 93% (>99% purity) for (2) and 94% (>99% purity) for (3). Characterization was accomplished using ¹H NMR, FTIR, melting point, TLC, HPLC, and GCMS. …

The Effects Of Human Behavioral Changes Due To The Covid-19 Pandemic On The Reservoir Of Lytic Escherichia Coli And Staphylococcus Aureus Bacteriophage On Humans At A South Carolina University, Korinne M. Swanson, Owen R. Smith, Paul E. Richardson

Journal of the South Carolina Academy of Science

Bacteriophages are viruses, whose unique ability to infect and lyse bacterial cells may provide valuable insight for evading the repercussions of a post-antibiotic era in medicine. This study isolated and characterized Escherichia coli and Staphylococcus aureus bacteriophage on students and faculty at Coastal Carolina University as a means to understand the viability of human bacteriophage reservoirs for bacteriophage therapy. From September 2021 to March 2022, nasal and postauricular swab samples and a behavioral survey were collected from ninety-three randomly selected participants. Additionally, sixteen participants contributed nasal and postauricular swab samples and a behavioral survey on a monthly basis in a …

Separation Of Track- And Shower-Like Energy Deposits In Protodune-Sp Using A Convolutional Neural Network, A. Abed Abud, B. Abi, R, Acciarri, M. A. Acero, M. R. Adames, G. Adamov, M. Adamowski, D. Adams, M. Adinolfi, A. Aduszkiewicz, M. Andreotti, M. Andrews, F. Andrianala, S. Andringa, N. Anfimov, A. Ankowski, M. Antoniassi, M. Antonova, A. Antoshkin, S. Antusch, Roberto Petti, Et. Al.

Faculty Publications

Liquid argon time projection chamber detector technology provides high spatial and calorimetric resolutions on the charged particles traversing liquid argon. As a result, the technology has been used in a number of recent neutrino experiments, and is the technology of choice for the Deep Underground Neutrino Experiment (DUNE). In order to perform high precision measurements of neutrinos in the detector, final state particles need to be effectively identified, and their energy accurately reconstructed. This article proposes an algorithm based on a convolutional neural network to perform the classification of energy deposits and reconstructed particles as track-like or arising from electromagetic …

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.

Tau Neutrinos In The Next Decade: From Gev To Eev, Roshan Mammen Abraham, Jamie Alvarez-Muñiz, Carlos A. Argüelles, Akitaka Ariga, Tomoko Ariga, Adam Aurisano, Dario Autiero, Mary Bishai, Nilay Bostan, Mauricio Bustamante, Austin Cummings, Valentin Decoene, André De Gouvêa, Giovanni De Lellis, Albert De Roeck, Peter B. Denton, Antonia Di Crescenzo, Milind V. Diwan, Yasaman Farzan, Anatoli Fedynitch, Jonathan L. Feng, Laura J. Fields, Alfonso Garcia, Maria Vittoria Garzelli, Julia Gehrlein, Christian Glaser, Katarzyna Grzelak, Steffen Hallmann, Jeremy Hewes, D Indumathi, Ahmed Ismail, Sudip Jana, Yu Seon Jeong, Kevin J. Kelly, Spencer R. Klein, Felix Kling, Thomas Kosc, Umut Kose, D Jason Koskinen, John Krizmanic, Jeff Lazar, Yichen Li, Ivan Martinez-Soler, Irina Mocioiu, Jiwoo Nam, Valentin Niess, Nepomuk Otte, Sameer Patel, Roberto Petti, Et. Al.

Faculty Publications

Tau neutrinos are the least studied particle in the standard model. This whitepaper discusses the current and expected upcoming status of tau neutrino physics with attention to the broad experimental and theoretical landscape spanning long-baseline, beam-dump, collider, and astrophysical experiments. This whitepaper was prepared as a part of the NuTau2021 Workshop.

Metabolome-Wide Associations Of Gestational Weight Gain In Pregnant Women With Overweight And Obesity, Jin Dai, Nansi S. Boghossian, Mark Sarzynski Ph.D., Faha, Facsm, Feng Luo, Xiaoqian Sun, Jian Li, Oliver Fiehn, Jihong Liu Sc.D., Liwei Chen

Faculty Publications

Excessive gestational weight gain (GWG) is associated with adverse pregnancy outcomes. This metabolome-wide association study aimed to identify metabolomic markers for GWG. This longitudinal study included 39 Black and White pregnant women with a prepregnancy body mass index (BMI) of ≥ 25 kg/m². Untargeted metabolomic profiling was performed using fasting plasma samples collected at baseline (mean: 12.1 weeks) and 32 weeks of gestation. The associations of metabolites at each time point and changes between the two time points with GWG were examined by linear and least absolute shrinkage and selection operator (LASSO) regression analyses. Pearson correlations between the …

Direct Measurement Of Stokes–Einstein Diffusion Of Cowpea Mosaic Virus With 19 Μs-Resolved Xpcs, Kacper Switalski, Jingyu Fang, Luxi Li, Miaoqi Chu, Erik Sarnello, Pete Jemian, Tao Li, Qian Wang, Qingteng Zhang

Faculty Publications

Brownian motion of Cowpea mosaic virus (CPMV) in water was measured using small-angle X-ray photon correlation spectroscopy (SA-XPCS) at 19.2 mu s time resolution. It was found that the decorrelation time tau(Q) = 1/DQ(2) up to Q = 0.091 nm(-1). The hydrodynamic radius R-H determined from XPCS using Stokes-Einstein diffusion D = kT/(6 pi eta R-H) is 43% larger than the geometric radius R-0 determined from SAXS in the 0.007 M K3PO4 buffer solution, whereas it is 80% larger for CPMV in 0.5 M NaCl and 104% larger in 0.5 M (NH4)(2)SO4, a possible effect of aggregation as well as …

Latest Results From The Cuore Experiment, I. Nutini, D. Q. Adams, C. Alduino, K. Alfonso, F. T. Avignone Iii, O. Azzolini, G. Bari, F. Bellini, M. Beretta, M. Biassoni, A. Branca, C. Brofferio, C. Bucci, J. Camilleri, A. Caminata, L. Canonica, X. G. Cao, S. Capelli, L. Cappelli, L. Cardani, Carl Rosenfeld Jr., Carl Rosenfeld, Et. Al.

Faculty Publications

The Cryogenic Underground Observatory for Rare Events (CUORE) is the frst cryogenic experiment searching for 0vββ decay that has been able to reach the onetonne mass scale. The detector, located at the Laboratori Nazionali del Gran Sasso (LNGS) in Italy, consists of an array of 988 TeO₂ crystals arranged in a compact cylindrical structure of 19 towers. CUORE began its frst physics data run in 2017 at a base temperature of about 10 mK and in April 2021 released its 3rd result of the search for 0vββ, corresponding to a tonne-year of TeO₂ exposure. This is the …

Utilization Of 18s Ribosomal Rna Lamp For Detecting Plasmodium Falciparum In Microscopy And Rapid Diagnostic Test Negative Patients, Enoch Aninagyei, Adjoa Agyemang Boakye, Clement Okraku Tettey, Kofi Adjei Nitri, Samuel Ohene Ofori, Comfort Dede Tetteh, Thelma Teley Alphour, Tanko Rufai

Faculty Publications

In this study, Plasmodium falciparum was detected in patients that were declared negative for malaria microscopy and rapid diagnostic test kit (mRDT), using Plasmodium 18s rRNA loop-mediated isothermal amplification (LAMP) technique. The main aim of this study was to assess the usefulness of LAMP assay for detecting pre-clinical malaria, when microscopy and mRDT were less sensitive. DNA was obtained from 100 μL of whole blood using the boil and spin method. Subsequently, the Plasmodium 18s rRNA LAMP assay was performed to amplify the specific Plasmodium 18s rRNA gene. Microscopy and mRDT negative samples [697/2223 (31.2%)] were used for this study. …

Broadening Participation In Tos Through Honors Nominations And Awards, Frank Muller-Karger, Eeshan Bhatt, Erin L. Meyer-Gutbrod

Faculty Publications

No abstract provided.

Extensions Of Discrete Choice Experiment Theory For Public Health, Farahnaz Islam

Theses and Dissertations

A discrete choice experiment (DCE) allows researchers to understand how individuals value characteristics of a product or service in hypothetical scenarios and the trade-offs these individuals are willing to make between these characteristics. DCEs quickly gained traction in public health but as more researchers utilized DCEs in broader contexts, several methodological questions have arisen. This dissertation addresses some of these gaps in the literature.

One critique of DCEs is whether individuals would make the same choice in reality as they claimed they would have made in the hypothetical scenario. Perhaps the most efficient way to evaluate the predictive value of …

Mechanistic Insights Into An Iron-Responsive Repressor, Fep1, From Schizosaccharomyces Pombe, Allison Nicole Kimsey

Theses and Dissertations

Iron is an essential metal cofactor required for a variety of biochemical pathways in most living organisms. In recent years, the nonpathogenic fungi Schizosaccharomyces pombe has been used to study iron regulation and uncover the molecular mechanisms for controlling intracellular iron levels. Some of these regulation pathways are conserved with those of pathogenic fungi, making these studies applicable for the future development of antifungals that target iron homeostasis. In S. pombe, the GATA-type transcriptional repressor Fep1 is responsible for repressing iron uptake genes during times of iron abundance. Previous reports have proposed that the binding of an iron-sulfur (Fe-S) …

Urban Flooding Accelerates The Affordable Housing Shortage: A Case Study In Columbia, South Carolina, Mary Hannah Lindsay

Theses and Dissertations

The state of South Carolina stands at the corner where climate change and the housing crisis meet. The affordable housing stock across South Carolina continues to deplete as its major cities experience urban flooding events due to outdated and weakened infrastructure, compounded by an intensification of storm systems brought on by a changing climate. Lower income communities are forced to accept lesser living conditions and less resilient housing options because these options are more affordable. Renters are often met with more challenges when navigating disaster recovery compared to homeowners. Using a case study established in Columbia, South Carolina of the …

Search For Triple-Proton Decay Using Machine Learning With Cuore, Douglas Adams

Theses and Dissertations

A framework to search for a triple-proton decay of ¹³⁰Te in the CUORE detector against a background of muons is presented. We use machine learning to classify different kinds of energy depositing events. We use the classification information to improve our detection or non-detection limits of a triple-proton decay process. We derive and use a methodology of combining Poisson counting statistics with supervised classification machine learning tools. Additionally, a sensitivity calculation is provided which uses the classification counting likelihood. Using our analysis technique, we achieve an lower 2σ half-life bound of 7.43×10²⁴yrs for triple-proton decay of …