Physical Sciences and Mathematics Commons^™

That’S My Deity: An Examination Of Online Lokean Cultures Through Log-Linear Modeling, Mary Bernstein

Senior Theses

A rise in online religious communities and the growth of so-called ‘Old World’ religions are reflected in the internet’s subcultures of Neopaganism, a growing religious movement that has been documented in America since the 1960s. The religions under this umbrella movement vary drastically and include belief systems such as Wicca, Druidry, and deity worship. Belief systems under this movement lack the traditional hierarchy found in structured religion and lack a singular sacred text. As such, believers usually find and support one another not through a physical sacred place of meeting, but through an online community that acts as sacred space. …

Survival Models With Background Mortality, Shujie Chen

Theses and Dissertations

In this dissertation, we focus on studying three mixture cure models with background mortality. With the development of treatment, patients may be cured and suffer from other cause of death. The cure model with background mortality can measure the population cure which refers to the patients with comparable mortality with their counterpart in general population. Three types of survival models are investigated, including generalized odds rate (GOR) model, cure model with background mortality for right censoring and interval censoring, and extended illness death model via incorporating “cure” fraction. All methods are validated via comprehensive simulation studies and real data application. …

Evaluation Of A Radium-Thorium Disequilibrium Sediment Method Used To Model And Assess Porewater And Submarine Groundwater Exchange In The Coastal Marsh, Madeline R. Bodine

Theses and Dissertations

Ground, pore, and surface water exchange has been extensively studied in beach and near shore environments but has been long neglected in saltmarsh systems due to their complexity. Saltmarsh systems are of particular importance as they are the interface between fresh and saltwater. Saltmarshes impact carbon exchange, release and sequestration, and they process particulate matter. Understanding the characteristics of a marsh system such as the nutrient and particulate loads in conjunction with the flux of water exchange through the marsh provides a deeper understanding of these systems and can impact our understanding of the global water and carbon cycles, as …

Surface And Alloy Engineering Of Halide Perovskite (Cspbx3) Nanocrystals For Efficient And Stable Optoelectronics, Sakiru L. Abiodun

Theses and Dissertations

Organic and inorganic halide perovskite quantum dots (QDs) (in form of ABX₃, where A is organic cation e.g CH₃NH₃⁺ or inorganic cation e.g Cs⁺) have emerged as an intriguing alternative to the widely studied chalcogenide and pnictide QDs. Their excellent optoelectronic properties such as large absorption coefficient, high carrier mobility, wide color gamut, long electron-hole diffusion lengths, and tunable bandgap energy are largely responsible for their wide acceptability in various electronic devices. However, despite this enthusiasm, the problem of purification, long-term stability, lead toxicity and inadequate knowledge of their surface chemistry still …

Detecting Spatially Varying Coefficient Effects With Conditional Autoregressive Models: A Simulation Study Using Social Determinants Of Health Screening Data, Reid J. Demass

Theses and Dissertations

Generalized linear models which include spatially varying coefficient terms allow researchers to determine if the association between predictor and outcome variables vary across geographic space. Such models are particularly applicable to research with public health data where interventions and limited health care resources must be allocated carefully. The integrated nested Laplace approximation (INLA) methodology available in the R INLA package is a popular tool to estimate spatially varying coefficients. To assess the performance of the estimation procedure, patient emergency department (ED) visits were simulated from data sourced from a pilot study at Prisma Health. The INLA technique was used to …

On The Algebraic And Geometric Multiplicity Of Zero As A Hypergraph Eigenvalue, Grant Ian Fickes

Theses and Dissertations

We consider the algebraic and geometric multiplicity of hypergraph eigenvalues, paying particular attention to nullities of hypertrees. Conjecture surrounds the relationship between these two multiplicites, but little work appears in the literature on this topic. Predominantly, we are interested in identifying the geometric structure of the nullvariety of certain hypergraph classes by listing the irreducible components and their accompanying dimensions. When applicable, we use this description to verify a conjecture relating the algebraic and geometric nullity. Furthermore, we refine these geometric structure tools to graph theoretic trees, defining a matroid on trees and relating skew zero forcing to the existence …

Bayesian Dependence Structure Analysis For Ordinal Data, Yang He

Theses and Dissertations

This dissertation explores different methods to study the dependence structure among many ordinal variables under the Bayesian framework.

Chapter 1 introduces ordinal data analysis methods, and the related literature works are briefly reviewed. An outline of the dissertation is put forward.

In Chapter 2, Gaussian copula graphical models with different priors of graphical Lasso, adaptive graphical Lasso, and spike-and-slab Lasso on the precision matrix are assessed and compared. The proposed models are well illustrated via simulations and a real ordinal survey data analysis.

In Chapter 3, adaptive spike-and-slab Lasso prior is proposed as an extension of Chapter 2. The developed …

Engineering Of Bio-Based And Synthetic Polymers: Synthesis And Application In Superabsorbent Materials And Antibacterial Agents, Jihyeon Hwang

Theses and Dissertations

A polymer consists of a large number of monomer units, which can be obtained naturally or via a chemical process called polymerization. Polymers are important materials that are used in our daily life. Life would not be possible without these polymers, either from plant biomass or petroleum-derived synthetic polymers. The substitution of petroleum-derived to biomass-based polymers has been highlighted to mitigate adverse environmental impact. However, the use of bio-based polymers is still a significant challenge for more demanding applications. In this dissertation work, the engineering of both bio-based and synthetic polymers and their properties are investigated.

In Chapter 1, the …

Structural And Immunological Characterization Of Inhaled Allergens And Their Complexes With Antibodies, Kriti Khatri

Theses and Dissertations

Allergy is an outcome of an allergen-antibody reaction (1). Potent airborne allergens from dust mites and pets are major causative factors for allergic conditions among predisposed individuals. Group-2 allergen Der p 2 from Dermatophagoides pteronyssinus is a major allergen which causes allergic conditions in more than 80% of mite-allergic subjects (2). Similarly, airborne allergen Can f 1 from dog (Canis familiaris) is also a major risk allergen which affects 10-20% of the population worldwide (3). Considering the increasing prevalence of inhalant allergens in the environment, antigenic characterization is crucial for improving allergy diagnostics and management. This study focuses …

Vaccinia Virus And Measles Virus As Oncolytic Vaccines: The Modulation Of The Viral Infectivity Via Surface Conjugations, Monchupa Kingsak

Theses and Dissertations

Oncolytic virus (OV) therapy has been shown to be an effective targeted cancer therapy treatment in recent years, providing an avenue of treatment that poses no damage to surrounding healthy tissues. Not only do OVs cause direct oncolysis, but they also amplify both innate and adaptive immune responses generating long-term antitumor immunity. However, a key challenge facing oncolytic virotherapy is neutralizing antibodies in vaccinated patients, leading to the viral clearance after systemic administration and failure in the treatment. The encapsulation of OVs using biocompatible polymers is one of the promising methods to prevent the viral clearance from antiviral immune responses. …

The Kinetic Control Of Polymer Micelles; Chemical Functionality, Material Interactions, And Equilibration, Taylor Larison

Theses and Dissertations

Polymer micelles have found significant uses in areas such as, energy storage devices, catalysis, opto-electronics, drug-delivery, oil additives, and nanoreactors. In many of these applications the overall micelle size (aggregation number) and chemical functionalization determines performance. To progress towards more advanced materials synthesized from the facile bottom-up approach with polymeric micelles the implementation and study of thermodynamic handles were investigated. Here the kinetic control of micelles was studied across a range of applications; independent control over micelle functionality, the spatial orientation of multiple metal oxide nanoparticles in mesoporous materials via self-assembly, and the use of small-angle neutron scattering (SANS) to …

Coordination Environment And Thermodynamics Of Colloidal Quantum Dots In Polar Solvents, Nuwanthaka Prasad Jayaweera Millaniyage

Theses and Dissertations

Colloidal semiconductor quantum dots (QDs) have been extensively investigated due to their attractive properties such as size-tunable absorption and emission spectra, large molar extinction coefficients, and significant photostability. These properties make them promising candidates for optoelectronic, photocatalytic, and biomedical applications. Common synthetic procedures of QDs produce nanocrystals capped with long-chain fatty acid derivatives which are stabilized in high boiling point solvents. Especially for bioimaging applications, the exchange of these native hydrophobic ligands with hydrophilic ligands should be performed, while preserving the smaller hydrodynamic radius. The coordination environment and thermodynamic parameters of the ligand exchanges should be carefully investigated to engineer …

Biochemical, Structural, And Immunological Characterization Of Selected Panallergens, Andrea Leigh O'Malley

Theses and Dissertations

Allergies throughout the world are increasing in prevalence and severity. Although the direct causes of the development of allergies are not confirmed, study of proteins that cause reactions will lead to a deeper understanding of allergy. This work focuses on three panallergen families, profilins, parvalbumins, and arginine kinases, to further elucidate the background of allergy from the point of view of the allergens themselves. In Chapter 1, we evaluate pollen, fruit, and mite profilins in the context of allergy, showing the relevance of conserved cysteine residues in stability and oligomerization as well as the first data on cross-reactivity between plant …

Reactive End Capped Polybenzimidazole Oligomers For High Temperature Thermosets And Improved Membranes For Electrochemical Devices, Caroline Marie Rohlfing

Theses and Dissertations

Polybenzimidazoles (PBI) are heterocyclic polymers that possess high thermal and oxidative stability. The inherent strength and chemical and thermal stability of PBI make it ideal for use in extreme environments; however, the current processing of PBI molded parts makes the process practically and economically unfavorable. These intrinsic properties make PBIs of particular interest for many industrial applications, varying from fabrics to membrane materials to molded parts. Processing these molded parts is extremely difficult, as the high glass transition temperature and extremely high melting point (>500°C) of PBI result in poor flow properties of PBI resins even at high temperatures. …

A Study Of Single Molecule Detection With Graphene Hall Bars, Kenneth Stephen Stephenson

Theses and Dissertations

In 2007, detection of individual molecules with a solid-state gas sensor was reported for first time by Schedin et al. where they used micromechanically-cleaved graphene for their sensing material, which exhibits isotropic and homogeneous conduction [1]. However, despite the novelty and popularity of their work, it has never been repeated. Further, we found their associated calculations to be self-inconsistent by a factor of 103 . So, hoping to account for and resolve this discrepancy, we outline the plan we had to reproduce their experiment. We also justify any substantial modifications, particularly our choice to use epitaxial graphene instead. Then, we …

Expanding Tailorable Nanomaterial Synthesis With Persistent Micelle Templates, Eric R. Williams

Theses and Dissertations

The control of block polymer micelle dimensions while in solution is critical for a range of emerging applications in diverse fields from drug delivery and nanoreactors to use as sacrificial templates for porous nanomaterials. When under kinetic control, micelles will maintain a constant average size and thus aggregation number (N_agg) through the suppression of chain exchange mechanisms. Such kinetic control effectively enables the decoupling of micelle dimensions from solution conditions. In other words, kinetically trapped micelles can resist reorganizations brough about by e.g., the addition of metal nanoparticles. However, such micelles are traditionally governed by a fickle �� …

Extreme Covering Systems, Primes Plus Squarefrees, And Lattice Points Close To A Helix, Jack Robert Dalton

Theses and Dissertations

This dissertation considers three different topics.

In the first part, we prove that if the least modulus of a distinct covering system is 4, its largest modulus is at least 60; also, if the least modulus is 3, the least common multiple of the moduli is at least 120; finally, if the least modulus is 4, the least common multiple of the moduli is at least 360. The constants 60, 120, and 360 are best possible, they cannot be replaced by larger constants. We also show that there do not exist distinct covering systems with all of the moduli in …

Advancements In Parametric Modal Regression, Qingyang Liu

Theses and Dissertations

This dissertation considers statistical inference methods for parametric modal regression models. In Chapter 1, we motivate the mode as the measure of central tendency instead of the median or the mean with an example. Following the motivational example, we include an overview of existing modal regression models. Later, in the same chapter, we explain advantages of the parametric modal regression models over existing nonparametric modal regression models. In Chapter 2, we address issues in statistical inference brought in by data contaminated with measurement error. With measurement error in covariates, statistical inference methods designed for modal regression models with error-free covariates …

Dust Production And Transport In A Long-Lived Fluvial-Eolian System In The Pampas Of South America, Blake Marcus Stubbins

Theses and Dissertations

Wind-blown dust from southern South America links the terrestrial, marine, atmospheric, and biologic components of Earth’s climate system. The Pampas of central Argentina (~33-40° S) contain an extensive upper Miocene to Holocene eolian record that spans the relatively warm conditions of the Late Miocene to cooler climates of the Plio-Pleistocene and Holocene. We collected 13 loess, paleosol, and fluvial samples from the upper Miocene Cerro Azul and Rio Negro Formations which resulted in n = 5129 new detrital zircon U-Pb ages. Late Miocene rivers conveyed sediment from northern Patagonia, the Andes adjacent to the Pampas, and the Sierras Pampeanas to …

Sustainable Approaches To Photo-, Thermo-, And Electro-Chemical Reactions Of Amines, James David Sitter

Theses and Dissertations

In recent years, sustainable routes for chemical synthesis have garnered renewed interest. As the world continues to fight pollution and rising costs, it is imperative that new routes of synthesis that continuously fight the issues of pollution and waste are discovered, defined and explored. While traditional synthesis routes that require energy input typically require the burning of fossil fuels to produce heat, the amount of resources that go into the production of these fossil fuels and the sequestration of its waste to minimize its impact on the carbon footprint is enormous. Furthermore, sustainable chemistry research aims to decrease and minimize …

Utilizing Deep Learning Methods In The Identification And Synthesis Of Gene Regulations, Jiandong Wang

Theses and Dissertations

Gene expression is the fundamental differentiation and development process of life. Although all cells in an organism have essentially the same DNA, cell types and activities vary due to changes in gene expression. Gene expression can be influenced by many gene regulations. RNA editing contributes to the variety of RNA and proteins by allowing single nucleotide substitution. Reverse transcription can alter the expression status of genes by inducing genetic diversity and polymorphism via novel insertions, deletions, and recombination events. Gene regulation is critical to normal development because it enables cells to respond rapidly to environmental changes. However, identifying gene regulations …

Exploring The Current Training Of Undergraduate Geology Students And Teaching Spatial Skills To Improve Student Outcomes, Ann Marie Klyce

Theses and Dissertations

Spatial skills, which represent the ability to mentally manipulate objects (Schneider & McGrew, 2012; Atit et al., 2020) have been shown to be correlated with entrance, persistence and success in STEM (Shea et al., 2001; Wai et al., 2009). Specifically, these skills have been shown to be necessary to geologists and geoscientists (Hegarty, 2014; Gagnier et al., 2016). While we recognize the importance of these skills, explicit training in them is rarely offered (NRC 2006). Consequently, cognitive scientists and discipline based education researchers have begun concerted efforts to offer training in spatial skills to improve student outcomes (e.g. Uttal et …

Semantics-Based Data Security Models, Theppatorn Rhujittawiwat

Theses and Dissertations

In this dissertation, we studied how an adversary could attack databases and how the system could prevent or recover from such an attack. Our motivation to improve the current security capabilities of database management systems. We provided better recovery capabilities of database management systems by incorporating data provenance. We also expand our study to express security and privacy needs of data in the Internet of Things (IoT) environments such as a smart home environment. For this, we proposed a stream data security model to theoretically represent the data in the IoT network. We built a dynamic authorization model on our …

Gamma Calibration Of Scintillators For The Muon Scattering Experiment, Anne Gloria Flannery

Theses and Dissertations

The MUon Scattering Experiment (MUSE) at the Paul Scherrer Institute seeks to measure the muon-proton and electron-proton elastic cross-sections in the same experiment by measuring the scattering angle of particles from a 115-160 MeV beam onto a liquid hydrogen target. The timing detectors, as well as several of other detectors in the experiment, are plastic scintillators. This document discusses a method for the energy calibration, using ²⁰⁸Tl, ²²Na, and 88Y sources, signal attenuation, and hit-position reconstructions of various timing detectors, as well as their function in the experiment as a whole. This method involves first attaining the pulse-height …

Structure Property Investigation And Applications Of Self-Assembled Triphenylamine Bis Urea Macrocycles, Md Faizul Islam

Theses and Dissertations

Porous organic crystals can be advantageous as nanoreactors and in sensing, separations, and storage. The Shimizu group utilizes bifurcated urea hydrogen bonding to direct the assembly small building block into pillars and columns affording functional porous crystals. Recently, our group has examined the incorporation of triphenylamines within the framework of bis-urea macrocycles. These macrocycles assemble into columns that contain the solvent of crystallization bound within the channels. Heating the crystals leads to removal of the solvent and activates the host for guest exchange by single-crystal-to-single[1]crystal transformations. Different electron accepting molecules can be encapsulated inside the pore of the host …

Molecular Devices For Measuring Weak Solvophobic Interactions And The Development Of Pedagogical Tools For Organic Chemistry Students, Alexander N. Manzewitsch

Theses and Dissertations

The main topics of this dissertation are: 1) the development and discussion of a new molecular balance for measuring alkyl-alkyl interactions in a wide array of organic solvents, 2) the development of linear solvation energy relationships between solvent interaction parameters and solvent accessible surface area (SASA) in CH-arene interactions, and 3) the development of online resources for helping undergraduate students perform organic chemistry mechanisms problems well.

The solvophobic effect, that is the forced association between two solutes due to intermolecular attraction of the solvent molecules, is ubiquitous in organic chemistry and responsible for many significant phenomena thereof. However, there is …

Learning Analytics Through Machine Learning And Natural Language Processing, Bokai Yang

Theses and Dissertations

The increase of computing power and the ability to log students’ data with the help of the computer-assisted learning systems has led to an increased interest in developing and applying computer science techniques for analyzing learning data. To understand and investigate how learning-generated data can be used to improve student success, data mining techniques have been applied to several educational tasks. This dissertation investigates three important tasks in various domains of educational data mining: learners’ behavior analysis, essay structure analysis and feedback providing, and learners’ dropout prediction. The first project applied latent semantic analysis and machine learning approaches to investigate …

Sparse Partitioned Empirical Bayes Ecm Algorithms For High-Dimensional Linear Mixed Effects And Heteroscedastic Regression, Anja Zgodic

Theses and Dissertations

Variable selection methods in both the frequentist and Bayesian frameworks are powerful techniques that provide prediction and inference in high-dimensional linear regression models. These methods often assume independence between observations and normally distributed errors with the same variance. In practice, these two assumptions are often violated. To mitigate this, we develop efficient and powerful Bayesian approaches for linear mixed modeling and heteroscedastic linear regression. These method offers increased flexibility through the development of empirical Bayes estimators for hyperparameters, with computationally efficient estimation through the Expectation Conditional-Minimization (ECM) algorithm. The novelty of these approaches lies in the partitioning and parameter expansion, …

Sensitivity Of The Cupid Experiment To Bragg-Primakoff Conversion Of Solar Axions And Alps, Kevin P. Wilson

Theses and Dissertations

The author reports in this dissertation on the application of a technique to use bolometer detector arrays, such as those of the CUORE experiment and its proposed upgrade CUPID, to search for 14.4 keV Solar axions arising from an M1 nuclear transition of thermally excited ⁵⁷Fe in the Solar core. Density functional theory calculations performed using QU A N T U M ESPRESSO for Li₂MoO₄ enable the computation of a time-dependent axionto-photon conversion rate in the bolometer crystals. These calculations predict that the proposed CUPID detector will be sensitive to Solar axions or axion-like particles that …

Making Music Social: Creating A Spotify-Based Social Media Platform, Dalton J. Craven

Senior Theses

DKMS is a new type of social media platform for music lovers and groups of friends. It integrates tightly with Spotify, one of the largest music streaming services in the world. Users of DKMS can see what their friends are listening to, receive recommendations of new songs to listen to, and analyze their several key numerical metrics (happiness, danceability, loudness, and energy) of their top songs.

DKMS was built as part of the year-long Capstone senior design course at the University of South Carolina. A deployed app is visible at https://dkms.vercel.app, and the open-source code is visible at https://github.com/SCCapstone/DKMS.