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Articles 31 - 60 of 7311
Full-Text Articles in Physical Sciences and Mathematics
Dynlp: Parallel Dynamic Batch Update For Label Propagation In Graph-Based Semi-Supervised Learning, S. M. Shovan, Arindam Khanda, S. M. Ferdous, Sajal K. Das, Mahantesh Halappanavar
Dynlp: Parallel Dynamic Batch Update For Label Propagation In Graph-Based Semi-Supervised Learning, S. M. Shovan, Arindam Khanda, S. M. Ferdous, Sajal K. Das, Mahantesh Halappanavar
Computer Science Faculty Research & Creative Works
Semi-supervised learning aims to infer class labels using only a small fraction of labeled data. In graph-based semi-supervised learning, this is typically achieved through label propagation to predict labels of unlabeled nodes. However, in real-world applications, new data often arrives in batches, and stale data often becomes irrelevant. Each time a new batch appears, reapplying the traditional label propagation algorithm to recompute all labels is redundant, computationally intensive, and inefficient. To address the absence of an efficient label propagation update method, we propose DynLP, a novel GPU-centric Dynamic Batched Parallel Label Propagation algorithm that performs only the necessary updates, propagating …
An Automated Electrochemistry Platform For Accelerating The Characterization Of Enzymatic Electrochemistry, Michael A. Pence, Zachary A. Nguyen, Luke G. Kays, Dylan G. Boucher, Joaquín Rodríguez-López, Shelley D. Minteer
An Automated Electrochemistry Platform For Accelerating The Characterization Of Enzymatic Electrochemistry, Michael A. Pence, Zachary A. Nguyen, Luke G. Kays, Dylan G. Boucher, Joaquín Rodríguez-López, Shelley D. Minteer
Chemistry Faculty Research & Creative Works
Enzymatic electrochemistry harnesses the selectivity of enzymes to enable electrochemical applications spanning sensing, synthesis, and energy conversion. However, the sequential nature of electroanalytical experiments limits throughput, restricting the scale at which enzyme-electrode systems can be screened. Here we demonstrate the capabilities of an automated electrochemistry platform, eLab, to increase the throughput of enzymatic electrochemistry investigations. We used the eLab to collect over 10,000 cyclic voltammograms across a large parameter space consisting of two enzyme variants (promiscuous and wild-type glucose oxidase), 20 saccharide substrates, 21 concentrations, and four scan rates, with measurements being made all in triplicate. The expansive dataset enabled …
Existence And Uniqueness Of Positive Solutions For Hilfer–Hadamard-Type Fractional Differential Equations With Γ-Concave And Sub-Homogeneous Operators, Hasan Rasouli, Hojjat Afshari, Martin Bohner
Existence And Uniqueness Of Positive Solutions For Hilfer–Hadamard-Type Fractional Differential Equations With Γ-Concave And Sub-Homogeneous Operators, Hasan Rasouli, Hojjat Afshari, Martin Bohner
Mathematics and Statistics Faculty Research & Creative Works
In this research, we present necessary and sufficient conditions for the existence and uniqueness of positive solutions for a class of Hilfer–Hadamard-type fractional differential equations with boundary value problems, including those with integral boundary conditions. The obtained results are conditional on a specific set of strong assumptions, which substantially narrow the class of admissible nonlinearities, coefficients, and boundary data. Thus, the present work extends the Hadamard-type framework to the Hilfer–Hadamard setting only within this restrictive regime, rather than providing a full extension to all Hilfer–Hadamard systems. We utilize the properties of (Formula presented.) -concave and sub-homogeneous operators along with two …
Digital Twin-Assisted Optimization Of 6g Wireless Networks: Ensuring Deterministic Communication, Yingpu Nian, Bo Yi, Xingwei Wang, Sajal K. Das
Digital Twin-Assisted Optimization Of 6g Wireless Networks: Ensuring Deterministic Communication, Yingpu Nian, Bo Yi, Xingwei Wang, Sajal K. Das
Computer Science Faculty Research & Creative Works
With the rapid advancement of 6G technology and the increasing use of smart devices, Deterministic 6G Wireless Networks (D6WN) have emerged to meet the growing network transmission demands. In particular, applications such as autonomous vehicles, remote surgery, and industrial automation require extremely low transmission latency to function effectively, highlighting the critical need for D6WN in supporting these time-sensitive use cases. Yet, the conventional TCP/IP framework lacks effective unified traffic and congestion control scheduling, aggravating latency and uncertainty, posing a challenge to ensuring reliable real-time critical applications. To address the challenges of deterministic transmission in D6WN, this paper integrates Digital Twin …
Hsv-1 Us3 Hijacks Conserved Actin Regulatory Complexes To Drive F-Actin Remodeling, Md Imran Hossain, Md Arifuzzaman, Md Mehedi Hasan, Seung Jong Park, Leila Rahimian, Ojasvi Dutta, Vladimir Chouljenko, Harikrishnan Mohan, Reza Ghavimi, Konstantin G. Kousoulas
Hsv-1 Us3 Hijacks Conserved Actin Regulatory Complexes To Drive F-Actin Remodeling, Md Imran Hossain, Md Arifuzzaman, Md Mehedi Hasan, Seung Jong Park, Leila Rahimian, Ojasvi Dutta, Vladimir Chouljenko, Harikrishnan Mohan, Reza Ghavimi, Konstantin G. Kousoulas
Computer Science Faculty Research & Creative Works
The herpes simplex virus 1 (HSV-1) US3 is a multifunctional serine/threonine kinase that promotes HSV-1 replication and spread. But its role and the mechanisms by which US3 regulates actin cytoskeletal remodeling remain poorly defined. We combined flow cytometry, confocal microscopy, immunoprecipitation-mass spectrometry (IP-MS), protein complex mapping, and machine learning to characterize US3-mediated F-actin dynamics. Flow cytometry and confocal microscopy showed that wild-type HSV-1 induces significant F-actin remodeling, while the ΔUS3 mutant displays F-actin levels comparable to uninfected cells, identifying US3 as a key regulator. IP-MS identified 47 high-confidence US3 interactors enriched in conserved actin regulatory complexes, including Arp2/3 nucleation machinery, …
Binding Energy Of Muonic Beryllium: Perturbative Versus All-Order Calculations, Shikha Rathi, Ulrich D. Jentschura, Paul Indelicato, Ben Ohayon
Binding Energy Of Muonic Beryllium: Perturbative Versus All-Order Calculations, Shikha Rathi, Ulrich D. Jentschura, Paul Indelicato, Ben Ohayon
Physics Faculty Research & Creative Works
We compute the ground-state binding energy of muonic (Formula presented) (Formula presented) Be in two ways: first, the fully perturbative treatment of the nuclear-size effect often employed in light systems, and second, an approach that accounts for the finite-nuclear-size to all orders (and is inspired by calculations otherwise employed for heavy muonic ions). The results are compared term by term and show that both approaches agree to better than one part-per-million of the total energy. The objective of this work is twofold. The first is practical: to provide a parameterization that allows the extraction of the (Formula presented) (Formula presented) …
Label-Flip Attack Detection Via Trust-Weighted Aggregation In Federated Learning For Underground Mine Security, Md Sazedur Rahman, Sanjay Madria, Samuel Frimpong
Label-Flip Attack Detection Via Trust-Weighted Aggregation In Federated Learning For Underground Mine Security, Md Sazedur Rahman, Sanjay Madria, Samuel Frimpong
Computer Science Faculty Research & Creative Works
Underground mining operations are increasingly dependent on autonomous vehicles, robotic drilling systems, and intelligent inspection platforms operating in confined, GPS-denied tunnel environments. These systems rely on distributed perception models to interpret navigation cues, hazard warnings, and environmental signals in real time. While centralized deep learning can enhance model performance, transferring raw operational data across mining sites introduces serious confidentiality and security risks. Federated Learning (FL) offers a privacy-preserving alternative by enabling collaborative model training without sharing local datasets. However, deploying FL in underground mining introduces several critical challenges: (i) Training labels may be modified either maliciously by compromised clients or …
Rheological Protocol To Assess And Optimize Latex Coagulation Dynamics For The Thin Glove Coagulant Dipping Process, Monday U. Okoronkwo, Kok Kong Ng, Wolfram Franke, Gaurav Sant
Rheological Protocol To Assess And Optimize Latex Coagulation Dynamics For The Thin Glove Coagulant Dipping Process, Monday U. Okoronkwo, Kok Kong Ng, Wolfram Franke, Gaurav Sant
Chemical and Biochemical Engineering Faculty Research & Creative Works
Many products that directly impact the quality of human life today — gloves, catheters, condoms, and baby bottle teats — are made through the latex-dipping technology. While a variety of methods have been developed – e.g., particle counting, turbidimetry, microscopy, and light scattering – which are suitable for studying the coagulation of latex at very low concentrations, much less work has focused on methods suitable for in-situ characterization of latex coagulation in concentrated solutions (e.g., as relevant to the dipping process). This paper presents a process-relevant rheological protocol for assessing and optimizing latex coagulation dynamics for the thin glove coagulant …
High-Throughput Optical Analysis To Inform Design Of Electrochemical Biosensors, Nathan J. Ricks, Michael A. Pence, Monica Brachi, Shelley D. Minteer
High-Throughput Optical Analysis To Inform Design Of Electrochemical Biosensors, Nathan J. Ricks, Michael A. Pence, Monica Brachi, Shelley D. Minteer
Chemistry Faculty Research & Creative Works
Electrochemical biosensors are central to wearable diagnostics, point-of-care testing, and continuous health monitoring due to their low power requirements, compatibility with miniaturized electronics, and proven clinical impact. Despite these advantages, the development of new electrochemical biosensors remains slow, constrained by limited throughput, complex electrode–biomolecule interfaces, and challenges associated with selectivity and performance in chemically complex environments. This perspective outlines how the next generation of electrochemical biosensors can be enabled by decoupling high-throughput front-end discovery and optimization from electrochemical readouts using nonelectrochemical surrogate assays. Optical, affinity, and cell-sorting platforms, including SELEX, fluorescence-activated cell sorting, and chemically coupled fluorescence assays, allow orders-of-magnitude …
Data-Driven Electrochemistry Reveals The Impact Of Hydrophobicity On Aptamer Cross-Reactivity, Emily Carroll, Michael A. Pence, Elizabeth Winterholler, Taylor D. Sparks, Shelley D. Minteer
Data-Driven Electrochemistry Reveals The Impact Of Hydrophobicity On Aptamer Cross-Reactivity, Emily Carroll, Michael A. Pence, Elizabeth Winterholler, Taylor D. Sparks, Shelley D. Minteer
Chemistry Faculty Research & Creative Works
Electrochemical aptamer-based (E-AB) biosensors offer a promising platform for reagentless detection of molecular targets, yet aptamer recognition can be limited by cross-reactivity, particularly for hydrophobic analytes such as steroid hormones. To investigate how cross-reactivity influences E-AB sensor performance, we use automation and machine learning to screen a library of possible interferent molecules against a steroid-binding aptamer, with progesterone serving as a physiologically relevant test case. Here, we develop a label-free E-AB sensor for progesterone detection using a methylene blue-modified aptamer anchored with a hexanethiol linker. We then used an automated electrochemistry platform to perform reproducible and high-throughput characterization of our …
Interseismic Creep Along The Enriquillo–Plantain Garden Fault, Haiti, Estimated From Insar, Rishabh Dutta, Jeremy L. Maurer, Yi Chieh Lee
Interseismic Creep Along The Enriquillo–Plantain Garden Fault, Haiti, Estimated From Insar, Rishabh Dutta, Jeremy L. Maurer, Yi Chieh Lee
Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works
The Enriquillo–Plantain Garden fault zone (EPGFZ) is a major left-lateral strike-slip fault in southern Haiti hosting several recent destructive earthquakes, including the 2021 MW 7.1 Nippes event with primary thrust-slip. To investigate how strain is accommodated in the vicinity of the 2021 event, we analyzed Sentinel-1 interferometric synthetic aperture radar (InSAR) data from 2017 to 2021 using a PS + DS (persistent + distributed scatterers) InSAR time-series approach to overcome decorrelation in this highly vegetated region. We reveal interseismic creep along the EPGF and adjacent Grand'Anse–Sud border faults, with pure strike-slip mechanism and rates up to 9 mm/yr. We suggest …
Design Framework For Polymer Gel Treatments From A Database Of Field Projects, Baojun Bai, Munqith Aldhaheri, Mingzhen Wei
Design Framework For Polymer Gel Treatments From A Database Of Field Projects, Baojun Bai, Munqith Aldhaheri, Mingzhen Wei
Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works
This study compiles and analyzes data from over 125 published field projects around the world, covering nearly 900 treated wells. Building on those detailed studies, this paper distills the most important findings into a concise, practical, and actionable framework to guide where in-situ gel treatments should be applied, how they should be designed, and how their outcomes can be evaluated. The proposed workflow guides engineers through five integrated stages: screening appropriate gel types, designing formulation and injection strategies, predicting field response, evaluating treatment performance, and conducting iterative refinement with feedback loops to adjust designs based on observed outcomes. The framework …
Employing Ac And Dc Electrolysis To Modulate Electroenzymatic Pathways For Efficient And Stereoselective H-D Exchange, Wassim El Housseini, Rokas Gerulskis, Nibedita Behera, Huaijun Guan, Rohit G. Jadhav, Zachary A. Nguyen, Egor Baiarashov, Michael A. Pence, Vamshi Krishna Kamaja, Trevor Larkin, Long Luo, Shelley D. Minteer
Employing Ac And Dc Electrolysis To Modulate Electroenzymatic Pathways For Efficient And Stereoselective H-D Exchange, Wassim El Housseini, Rokas Gerulskis, Nibedita Behera, Huaijun Guan, Rohit G. Jadhav, Zachary A. Nguyen, Egor Baiarashov, Michael A. Pence, Vamshi Krishna Kamaja, Trevor Larkin, Long Luo, Shelley D. Minteer
Chemistry Faculty Research & Creative Works
Stereoselective hydrogen isotope exchange (HIE) at chiral centers is an increasingly important strategy for preparing labeled molecules, yet its practical implementation depends on reliable control of nicotinamide cofactor regeneration. Here we introduce a redox-programmable electroenzymatic platform for stereoselective HIE based on electrode-controlled manipulation of the nicotinamide cofactor state. A wired ferredoxin–NADP+ reductase (FNR) electrode enables reversible electrochemical interconversion of NADP+ and its deuterated reduced form (NADPD) directly from D2O. Coupling this cofactor cycling with enantioselective alcohol dehydrogenases (ADHs) establishes a reversible alcohol–ketone redox manifold that drives efficient and stereoselective H-D exchange at chiral alcohols. Stereochemical outcomes are programmed …
Enhanced Uav Surveillance With Rf-Based Drone Identification Using Transfer Learning, Prajoy Podder, Maciej Jan Zawodniok, Sanjay Madria
Enhanced Uav Surveillance With Rf-Based Drone Identification Using Transfer Learning, Prajoy Podder, Maciej Jan Zawodniok, Sanjay Madria
Electrical and Computer Engineering Faculty Research & Creative Works
With the development of technology and the decrease in costs, drones are now becoming easily accessible to the public. As the accessibility of this technology continues to grow, the concerns of security and surveillance increase, and to ensure a sense of security, the need to have reliable drone detection and identification systems is more urgent than ever. Besides, many civilian applications have been found for drones, which play a huge role in modern security and warfare. Unauthorized drones can be very dangerous regarding security issues, as they can be used for spying, smuggling, or even attacks against critical infrastructure. We …
Investigation Of Portland Limestone Cement Blended With Biochar From Downdraft Gasification: Hydration Kinetics, Microstructure, Rheology, And Performance Mechanisms, Ugochukwu Ewuzie, Paul C. Ani, Abdulkareem O. Yusuf, Joseph D. Smith, Monday Uchenna Okoronkwo
Investigation Of Portland Limestone Cement Blended With Biochar From Downdraft Gasification: Hydration Kinetics, Microstructure, Rheology, And Performance Mechanisms, Ugochukwu Ewuzie, Paul C. Ani, Abdulkareem O. Yusuf, Joseph D. Smith, Monday Uchenna Okoronkwo
Chemical and Biochemical Engineering Faculty Research & Creative Works
The widespread adoption of Portland Limestone Cement (PLC) in U.S. concrete production has necessitated research into commercially available supplementary cementitious materials (SCMs) for formulating high-performance, low-carbon blended binders with PLC. This study investigated the influence of biochar (BC) in biochar-PLC composites (CBCs), focusing on hydration kinetics, microstructure, rheology, pore-solution chemistry, compressive strength, and the underlying mechanisms. Biochar was produced via downdraft gasification at 850 °C and incorporated into PLC at 5, 7, and 10% substitution by mass. Isothermal calorimetry and hydration data modeled using the Knudsen equation revealed that BC retarded early hydration but improved hydration degree and later-age heat …
Olaf: Towards Robust Llm-Based Annotation Framework In Empirical Software Engineering, Mia Mohammad Imran, Tarannum Shaila Zaman
Olaf: Towards Robust Llm-Based Annotation Framework In Empirical Software Engineering, Mia Mohammad Imran, Tarannum Shaila Zaman
Computer Science Faculty Research & Creative Works
Large Language Models (LLMs) are increasingly used in empirical software engineering (ESE) to automate or assist annotation tasks such as labeling commits, issues, and qualitative artifacts. Yet the reliability and reproducibility of such annotations remain underexplored. Existing studies often lack standardized measures for reliability, calibration, and drift, and frequently omit essential configuration details. We argue that LLM-based annotation should be treated as a measurement process rather than a purely automated activity. In this position paper, we outline the Operationalization for LLM-based Annotation Framework (OLAF), a conceptual framework that organizes key constructs: reliability, calibration, drift, consensus, aggregation, and transparency. The paper …
A Fiftieth Year Retrospective On The 1976 Mw 7.5 Motagua Earthquake In Guatemala, Grant Clark, Trenton Mcenaney, Jeremy Maurer, Andreas Eckert, Stephen S. Gao, Omar G. Flores, Robin Yani, Tina Niemi, Christoph Grützner, Francisco Gomez, Jonathan Obrist-Farner
A Fiftieth Year Retrospective On The 1976 Mw 7.5 Motagua Earthquake In Guatemala, Grant Clark, Trenton Mcenaney, Jeremy Maurer, Andreas Eckert, Stephen S. Gao, Omar G. Flores, Robin Yani, Tina Niemi, Christoph Grützner, Francisco Gomez, Jonathan Obrist-Farner
Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works
On 4 February 1976, an Mw > 7:5 earthquake ruptured ∼240 km of the Motagua fault in Guatemala, causing ∼23,000 fatalities. This event provided evidence for the fault's role as a major transform boundary between the North American and Caribbean plates. Field observations, seismological analyses, and postseismic studies helped constrain fundamental aspects of the 1976 earthquake mechanics and the spatial complexity of the rupture. This event opened a window for studies documenting past deformation along this plate boundary across multiple spatial and temporal scales. Five decades of research have established this earthquake as an important event for understanding strike-slip ruptures along …
Golden And Silver Dark Sirens For Precise H0 Measurement With Hetdex, Yixuan Dang, Ish Gupta, Robin Ciardullo, Erin Mentuch Cooper, Shiksha Pandey, Dustin Davis, Surhud More, Rachel Gray, Hsin Yu Chen, Daniel J. Farrow, Caryl Gronwall, Donghui Jeong, Shun Saito, Donald P. Schneider
Golden And Silver Dark Sirens For Precise H0 Measurement With Hetdex, Yixuan Dang, Ish Gupta, Robin Ciardullo, Erin Mentuch Cooper, Shiksha Pandey, Dustin Davis, Surhud More, Rachel Gray, Hsin Yu Chen, Daniel J. Farrow, Caryl Gronwall, Donghui Jeong, Shun Saito, Donald P. Schneider
Physics Faculty Research & Creative Works
Gravitational waves (GWs) from compact binary coalescences are standard sirens that provide a direct measure of the source's luminosity distance, enabling an independent measurement of the Hubble constant (H0). While a bright siren—a GW event with an identified electromagnetic (EM) counterpart—provided the first such constraint, most detections, currently dominated by black hole mergers, lack EM signatures. A measurement of H0 is still possible with these dark sirens by statistically associating GW events with galaxies in existing catalogs based on the sky localization. In this work, we explore the potential of two subsets of dark sirens categorized by their localization precision: …
Phases And Dynamics Of An Impurity Immersed In One-Dimensional Quantum Droplets, Dimitrios Diplaris, Ilias A. Englezos, Friethjof Theel, Peter Schmelcher, Simeon I. Mistakidis
Phases And Dynamics Of An Impurity Immersed In One-Dimensional Quantum Droplets, Dimitrios Diplaris, Ilias A. Englezos, Friethjof Theel, Peter Schmelcher, Simeon I. Mistakidis
Physics Faculty Research & Creative Works
We explore the ground-state properties of a single impurity immersed in a one-dimensional quantum droplet medium formed by a two-component Bose mixture. Relying on ab initio simulations, we demonstrate that tuning the impurity–droplet interactions allows to controllably reshape the droplets' density profiles and associated correlation patterns. For attractive impurity-medium couplings, the impurity becomes localized within the droplet, which exhibits a density hump at the vicinity of the impurity, while repulsive interactions facilitate phase separation. Comparing our many-body results with the appropriate extended Gross–Pitaevskii description, we find adequate agreement for the droplet density profiles, with the effective field approach systematically overestimating …
Pso-Style Social Influence In An Ant Colony Algorithm For Continuous-Domain Optimization, Ashraf M. Abdelbar, Donald C. Wunsch
Pso-Style Social Influence In An Ant Colony Algorithm For Continuous-Domain Optimization, Ashraf M. Abdelbar, Donald C. Wunsch
Electrical and Computer Engineering Faculty Research & Creative Works
ACOR is a well-established Ant Colony Optimization (ACO) algorithm for continuous-domain optimization. In this paper, we propose an extension (which we call ACOR∗) in which several fundamental modifications are made to ACOR's solution construction process, including the incorporation of a social influence mechanism borrowed from Particle Swarm Optimization (PSO). Our modifications to the ACOR algorithm are intended to promote search diversity and combat premature convergence. We experimentally evaluate our proposal in the context of training feedforward neural networks for classification using 65 widely used datasets from the University of California Irvine (UCI) repository, as well as the optimization of several …
Phase Field Modeling And A Fully Discrete Numerical Scheme For Two-Phase Incompressible Mhd Flows With Different Densities, Electric Conductivities And Viscosities, Xiaoyong Chen, Rui Li, Jian Li, Xiaoming He, Yanping Lin
Phase Field Modeling And A Fully Discrete Numerical Scheme For Two-Phase Incompressible Mhd Flows With Different Densities, Electric Conductivities And Viscosities, Xiaoyong Chen, Rui Li, Jian Li, Xiaoming He, Yanping Lin
Mathematics and Statistics Faculty Research & Creative Works
This article establishes a phase field model for governing the two-phase incompressible MHD flows with different densities, electric conductivities, and viscosities. In addition to the coupling between the Cahn–Hilliard phase field equations and the single-phase MHD equations together with the varying parameters, it is physically faithful and mathematically rigorous for the modeling to incorporate a relative flux term, which is related to the diffusion of the components, into the coupled system, inspired by Abels et al. and Shen and Yang. We present a linear fully discrete numerical scheme for this complex multi-physics system, which leverages the artificial compressibility method, an …
Explicit Hydration Of The Beryllium Trifluoride Anion With One To Three Water Molecules: Bef3–(H2o)N=1–3, Kayleigh R. Autry, Gregory S. Tschumper
Explicit Hydration Of The Beryllium Trifluoride Anion With One To Three Water Molecules: Bef3–(H2o)N=1–3, Kayleigh R. Autry, Gregory S. Tschumper
Chemistry Faculty Research & Creative Works
This work investigates the micro hydration of the beryllium trifluoride anion (BeF3–) with up to three water molecules (BeF3–(H2O)n where n = 1–3). Full geometry optimizations and harmonic vibrational frequencies were computed on various BeF3–(H2O)n stationary points using density functional theory methods (B3LYP-D3BJ, B3LYP, ωB97XD, and M06-2X) as well as the CCSD(T) and MP2 ab initio methods with a triple-ζ correlation-consistent basis set augmented with diffuse functions on all non-hydrogen atoms (haTZ). One BeF3–(H2O)1, five BeF3– …
Genetic Analysis Of Triplicated Genes Affecting Sex-Specific Skeletal Deficits In Down Syndrome Model Mice, Kourtney Sloan, Kristina M. Piner, Pathum Randunu Nawarathna Kandedura Arachchige, Charles R. Goodlett, Yann Herault, Gayla R. Olbricht, Joseph M. Wallace, Randall J. Roper
Genetic Analysis Of Triplicated Genes Affecting Sex-Specific Skeletal Deficits In Down Syndrome Model Mice, Kourtney Sloan, Kristina M. Piner, Pathum Randunu Nawarathna Kandedura Arachchige, Charles R. Goodlett, Yann Herault, Gayla R. Olbricht, Joseph M. Wallace, Randall J. Roper
Mathematics and Statistics Faculty Research & Creative Works
Down syndrome (DS) is caused by the triplication of human chromosome 21 (Hsa21), resulting in skeletal insufficiency (low bone mineral density) and altered bone development. DS mouse models recapitulate these deficits, including sexual dimorphism in long bone alterations. Historically, Ts65Dn mice provided much of the insight behind DS-related skeletal deficits with ∼100 trisomic orthologous genes, but there are concerns about the genetic fidelity in this model due to the included triplication of genes not homologous to Hsa21. A new DS model, Ts66Yah, subtracted the non-Hsa21 homologous trisomic genes from Ts65Dn but has not been evaluated for long bone deficits. Comparing …
Multi-Population Sufficient Dimension Reduction, Xuerong Meggie Wen, Yuexiao Dong, Li Xing Zhu
Multi-Population Sufficient Dimension Reduction, Xuerong Meggie Wen, Yuexiao Dong, Li Xing Zhu
Mathematics and Statistics Faculty Research & Creative Works
A novel dimension-reduction method is introduced for multi-population data. The approach conducts a joint analysis that exploits information shared across populations while accommodating population-specific effects. Unlike partial dimension reduction methods, which identify related directions across all populations, or conditional analyses conducted independently within each population, the proposed two-step procedure leverages cross-population information to enhance estimation accuracy. The methodology is demonstrated through simulations and two real-data applications.
A Low-Rank Solver For The Stokes–Darcy Model With Random Hydraulic Conductivity And Beavers–Joseph Condition, Yujun Zhu, Yulan Ning, Zhipeng Yang, Xiaoming He, Ju Ming
A Low-Rank Solver For The Stokes–Darcy Model With Random Hydraulic Conductivity And Beavers–Joseph Condition, Yujun Zhu, Yulan Ning, Zhipeng Yang, Xiaoming He, Ju Ming
Mathematics and Statistics Faculty Research & Creative Works
This paper proposes, analyzes, and demonstrates an efficient low-rank solver for the stochastic Stokes-Darcy interface model with a random hydraulic conductivity both in the porous media domain and on the interface. We consider three interface conditions with randomness, including the Beavers–Joseph interface condition with the random hydraulic conductivity, on the interface between the free flow and the porous media flow. Our solver employs a novel generalized low-rank approximation of the large-scale stiffness matrices, which can significantly cut down the computational costs and memory requirements associated with matrix inversion without losing accuracy. Therefore, by adopting a suitable data compression ratio, the …
Smart-Charge: Stable Matching Algorithm For Electric Vehicle Charging In Subscription-Based Models, Arindam Khanda, Anurag Satpathy, Sajal K. Das
Smart-Charge: Stable Matching Algorithm For Electric Vehicle Charging In Subscription-Based Models, Arindam Khanda, Anurag Satpathy, Sajal K. Das
Computer Science Faculty Research & Creative Works
The transition from internal combustion engine (ICE) to electric vehicles (EVs) introduces several challenges, including limited charging infrastructure, unpredictable charging wait times, and inefficient selection of charging points (CPs). To address these issues, we propose SMART-CHARGE, a framework that efficiently assigns EVs to CPs through an edge-level coordination mechanism within each service region, enforced by roadside units (RSUs). Operating under a novel subscription-based charging model, SMART-CHARGE enforces predefined charging time limits via service-level agreements (SLAs). The EV-CP assignment problem is formulated as a one-to-many matching game that captures EV user preferences. To construct bounded yet efficient EV coalitions at each …
Safepass: Efficient Emergency Vehicle Passage With Minimal Disruption To Traffic Flow, Osho Osho, Suchetana Chakraborty, Sajal K. Das
Safepass: Efficient Emergency Vehicle Passage With Minimal Disruption To Traffic Flow, Osho Osho, Suchetana Chakraborty, Sajal K. Das
Computer Science Faculty Research & Creative Works
Emergency vehicle passage in congested urban networks poses a dual challenge: ensuring rapid response while minimizing disruption to surrounding traffic. This study addresses this challenge in the context of Connected Autonomous Emergency Vehicles (CA-EVs), proposing SafePass , a lightweight distributed framework for seamless CA-EV passage through decentralized, cooperative maneuvering of surrounding Connected Autonomous Non-Emergency Vehicles (CA-NEVs). At its core, SafePass employs the Target Lane Potential (TLP), a novel utility-based metric combining lane-choice utility with probabilistic gap acceptance, augmented by a cascade-aware penalty that suppresses upstream shockwaves triggered by gap-creation maneuvers. Evaluated in Simulation of Urban Mobility (SUMO) using synthetic traffic …
Probing Composition Effects On The Intrinsic Energetics Of Proton Transfer In Binary (Hcl)M(H2o)N Clusters, Max R. Tucker, Sarah N. Arradondo, Olivia M. Longsworth, George C. Shields, Gregory S. Tschumper
Probing Composition Effects On The Intrinsic Energetics Of Proton Transfer In Binary (Hcl)M(H2o)N Clusters, Max R. Tucker, Sarah N. Arradondo, Olivia M. Longsworth, George C. Shields, Gregory S. Tschumper
Chemistry Faculty Research & Creative Works
This work examines the effects on intrinsic energetics as the composition of finite (HCl)m(H2O)n cluster families containing at least one water molecule is changed at the molecular level, where m ≥ 2 and m + n = 4 − 6, and the associated (Cl−)x(H3O+)x(HCl)m−x(H2O)n−x clusters resulting from the dissociation of x HCl fragments via proton transfer (PT). They are collectively labeled m:n, and xPT indicates the degree of dissociation, from 0PT (no dissociation) up to 3PT. More than 1000 unique minima …
Mechanism Of Improved Miscibility Of Co2–Oil Systems By Multiester-Headgroup Surfactants, Ning Xu, Yanling Wang, Baojun Bai, Yu Zhang, Wenjing Shi, Zhaonian Zhang, Wenhui Ding, Peixu Ma, Zan Gao
Mechanism Of Improved Miscibility Of Co2–Oil Systems By Multiester-Headgroup Surfactants, Ning Xu, Yanling Wang, Baojun Bai, Yu Zhang, Wenjing Shi, Zhaonian Zhang, Wenhui Ding, Peixu Ma, Zan Gao
Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works
In the pursuit of carbon neutrality, the CO2-enhanced oil recovery provides dual benefits by enabling both carbon sequestration and incremental oil production. However, its application is limited by high minimum miscibility pressure. CO2-philic and oil-affinitive surfactants have emerged as an effective, low-dosage, and cost-efficient strategy to reduce the minimum miscibility pressure. In this study, macroscopic phase behavior experiments combined with molecular dynamics simulations were employed to systematically elucidate the influence of multiester-head surfactants on CO2–oil miscibility. Using a modified pressure–volume–temperature apparatus equipped with optical power monitoring, we determined that multiester-head surfactants reduced the first-contact …
Uptake And Fate Of Silver And Zinc Engineered Nanoparticles In Maize Under Single And Binary Dosing Soil Ecosystems, Lei Xu, Qingbo Yang, Xingmao Ma, Honglan Shi, John Yang, Hu Yang, Samira Mahdi, Ying Wang, Young Shin Jun
Uptake And Fate Of Silver And Zinc Engineered Nanoparticles In Maize Under Single And Binary Dosing Soil Ecosystems, Lei Xu, Qingbo Yang, Xingmao Ma, Honglan Shi, John Yang, Hu Yang, Samira Mahdi, Ying Wang, Young Shin Jun
Chemistry Faculty Research & Creative Works
Recent agricultural applications of engineered metallic nanoparticles (ENPs) have raised concerns about their uptake and fate in plants. To understand this critical issue, this study investigated the fate and uptake of silver (Ag) and zinc oxide (ZnO) ENPs in maize (Zea mays L.) after single or binary ENP exposure in soil. Results indicated that both Zn and Ag elemental concentrations in roots increased with increasing ENP dosage. Ag NPs in the tissues were detected, but not Zn NPs. Ag NP concentration was 3 times higher in the roots than in the shoots at low Ag NP dosing, while Ag NP …