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Articles 13681 - 13710 of 55623
Full-Text Articles in Public Health
Lessons Learned From Interdisciplinary Efforts To Combat Covid-19 Misinformation: Development Of Agile Integrative Methods From Behavioral Science, Data Science, And Implementation Science, Sahiti Myneni, Paula Cuccaro, Sarah Montgomery, Vivek Pakanati, Jinni Tang, Tavleen Singh, Olivia Dominguez, Trevor Cohen, Belinda Reininger, Lara S Savas, Maria E Fernandez
Lessons Learned From Interdisciplinary Efforts To Combat Covid-19 Misinformation: Development Of Agile Integrative Methods From Behavioral Science, Data Science, And Implementation Science, Sahiti Myneni, Paula Cuccaro, Sarah Montgomery, Vivek Pakanati, Jinni Tang, Tavleen Singh, Olivia Dominguez, Trevor Cohen, Belinda Reininger, Lara S Savas, Maria E Fernandez
Faculty, Staff and Student Publications
BACKGROUND: Despite increasing awareness about and advances in addressing social media misinformation, the free flow of false COVID-19 information has continued, affecting individuals' preventive behaviors, including masking, testing, and vaccine uptake.
OBJECTIVE: In this paper, we describe our multidisciplinary efforts with a specific focus on methods to (1) gather community needs, (2) develop interventions, and (3) conduct large-scale agile and rapid community assessments to examine and combat COVID-19 misinformation.
METHODS: We used the Intervention Mapping framework to perform community needs assessment and develop theory-informed interventions. To supplement these rapid and responsive efforts through large-scale online social listening, we developed a …
The Future Of Community Health Center Executive Leadership A Mixed-Method Formative Evaluation, Lizbeth Bayardo Cardenas
The Future Of Community Health Center Executive Leadership A Mixed-Method Formative Evaluation, Lizbeth Bayardo Cardenas
CGU Theses & Dissertations
This is a formative evaluation study of the California Primary Care Association's (CPCA) Leadership Equity Program, developed in response to the need for greater alignment between the communities accessing care provided by Community Health Centers and the representativeness of their future executive leaders. Community Health Centers (CHC) are a critical network of primary healthcare systems that deliver high-quality, comprehensive healthcare services to patients predominantly from under-resourced and marginalized communities of color. The study used a mixed-method concurrent triangulation design to describe how participants perceived the program achieved its goals and objectives using Kirkpatrick's Model and systems thinking. The study integrated …
An Analysis Of Water Quality At Orange County, California Beaches, Naomi Meurice
An Analysis Of Water Quality At Orange County, California Beaches, Naomi Meurice
Pomona Senior Theses
Beaches in Southern California are highly recreated by residents and visitors, making beaches socially and economically important. Public health departments in coastal communities are in charge of measuring water quality and ensuring it is safe for users. Research in the past has indicated that beach water quality gets worse after storms, with bacteria levels jumping on the day of a storm and staying high for up to five days. Studies have shown these spikes in bacteria to be associated with storm runoff, with beaches closer to runoff discharge locations experiencing more impact. However, prior research has not considered the period …
The Relationship Between Clinical Examination Measures And Ultrasound Measures Of Fascia Thickness Surrounding Trunk Muscles Or Lumbar Multifidus Fatty Infiltrations: An Exploratory Study, Christian Larivière, Richard Preuss, Dany H. Gagnon, Hakim Mecheri, Mark Driscoll, Sharon M. Henry
The Relationship Between Clinical Examination Measures And Ultrasound Measures Of Fascia Thickness Surrounding Trunk Muscles Or Lumbar Multifidus Fatty Infiltrations: An Exploratory Study, Christian Larivière, Richard Preuss, Dany H. Gagnon, Hakim Mecheri, Mark Driscoll, Sharon M. Henry
Études primaires
Patients with chronic low back pain (CLBP) exhibit remodelling of the lumbar soft tissues such as muscle fatty infiltrations (MFI) and fibrosis of the lumbar multifidus (LuM) muscles, thickness changes of the thoracolumbar fascia (TLF) and perimuscular connective tissues (PMCT) surrounding the abdominal lateral wall muscles. Rehabilitative ultrasound imaging (RUSI) parameters such as thickness and echogenicity are sensitive to this remodelling. This experimental laboratory study aimed to explore whether these RUSI parameters (LuM echogenicity and fascia thicknesses), hereafter called dependent variables (DV) were linked to independent variables (IV) such as (1) other RUSI parameters (trunk muscle thickness and activation) and …
Prerequisite For Imputing Non-Detects Among Airborne Samples In Osha’S Imis Databank: Prediction Of Sample’S Volume, Igor Burstyn, Philippe Sarazin, George Luta, Melissa C. Friesen, Laurel Kincl, Jérôme Lavoué
Prerequisite For Imputing Non-Detects Among Airborne Samples In Osha’S Imis Databank: Prediction Of Sample’S Volume, Igor Burstyn, Philippe Sarazin, George Luta, Melissa C. Friesen, Laurel Kincl, Jérôme Lavoué
Études primaires
Introduction: The US Integrated Management Information System (IMIS) contains workplace measurements collected by Occupational Safety and Health Administration (OSHA) inspectors. Its use for research is limited by the lack of record of a value for the limit of detection (LOD) associated with non-detected measurements, which should be used to set censoring point in statistical analysis. We aimed to remedy this by developing a predictive model of the volume of air sampled (V) for the non-detected results of airborne measurements, to then estimate the LOD using the instrument detection limit (IDL), as IDL/V.
Methods: We obtained the Chemical Exposure Health Data …
Integrating Feminist Approaches In Counseling Work With Adult Women, Kristen M. Toole
Integrating Feminist Approaches In Counseling Work With Adult Women, Kristen M. Toole
Adultspan Journal
The scope of ‘women’s issues’ in counseling is an ever-evolving landscape. Recent events such as the reversal of Roe v. Wade and the disproportionate impact of COVID-19 on women serve as powerful reminders of the necessity of this focus while underscoring a deep-rooted history of oppressive patriarchal structures. Therefore, counselors must remain informed of the unique considerations surrounding adult women in counseling and acquire proficiency in versatile techniques to meet this population’s nuanced needs. This article examines the complexity of contemporary womanhood and explores the fundamentals of Feminist Counseling Theory (FCT), a holistic, multiculturally conscious, social justice theory in counseling. …
Impact Of Race And Socioeconomic Factors On Infant Mortality Between Non-Hispanic Black And White Women, Chukuma Clifton Chijioke
Impact Of Race And Socioeconomic Factors On Infant Mortality Between Non-Hispanic Black And White Women, Chukuma Clifton Chijioke
Walden Dissertations and Doctoral Studies
Abstract This quantitative retrospective study with a correlational design examined the impact of race and socioeconomic factors on the high infant mortality (IM) among non-Hispanic Black women compared to non-Hispanic White women in one midwestern US state county. Though the IM in the U.S. has consistently decreased, a disparity exists between non-Hispanic Black and non-Hispanic White women. Non-Hispanic Black women are twice as likely to experience infant deaths as non-Hispanic White women. This study utilized secondary data derived from vital records maintained by the county public health department. The research was grounded in the ecological model. Logistic regression was used …
Poisson Regression Model With Application To Wastewater Surveillance Under A Threshold Linear Mixed Model For Covid-19 Sensitivity Rates, Norou Diawara, Hueiwang Anna Jeng, Kyle Curtis, Raul Gonzalez, Nancy Welch, Cynthia Jackson, Rekha Singh, David Jurgens, Sasanka Adikari, Omotomilola Jegede
Poisson Regression Model With Application To Wastewater Surveillance Under A Threshold Linear Mixed Model For Covid-19 Sensitivity Rates, Norou Diawara, Hueiwang Anna Jeng, Kyle Curtis, Raul Gonzalez, Nancy Welch, Cynthia Jackson, Rekha Singh, David Jurgens, Sasanka Adikari, Omotomilola Jegede
Mathematics & Statistics Faculty Publications
A Threshold Linear Mixed Model (TLMM) has been developed to identify specific thresholds based on wastewater SARS-CoV-2 viral concentrations, which reflect COVID-19 cases. The thresholds can guide decisions regarding public health responses and prevention measures. To assess the practical application of TLMM, a simple simulation was conducted using a sample size of 100 and 500 replications. The simulation allowed for comparing parameter estimators by assessing bias and standard deviation and the root of the mean square error. The model and estimation procedures were applied to reported wastewater and clinic data to test its application for real-world scenarios. Our results demonstrated …
Livestock Cattle As A Predictor Of Schistosomiasis Transmission In Nigeria, Oyetunde T. Oyeyemi, Oluyemi A. Okunlola, Zhiqiang Fu, Yang Hong, Jun-Hu Chen, Lisa M. Shollenberger
Livestock Cattle As A Predictor Of Schistosomiasis Transmission In Nigeria, Oyetunde T. Oyeyemi, Oluyemi A. Okunlola, Zhiqiang Fu, Yang Hong, Jun-Hu Chen, Lisa M. Shollenberger
Biological Sciences Faculty Publications
Livestock cattle have been widely linked to schistosomiasis epidemiology, but little is known about its contribution to schistosomiasis transmission in Nigeria. The aim of this study is to examine the association between prevalence of schistosomiasis and livestock cattle index in Nigeria. The study's data came from three sources: the demographic and health survey (DHS), the malaria indicators survey (MIS), and the expanded special project for the eradication of neglected tropical diseases (ESPEN). Analysis of variance, correlation, and logistic regression were used to evaluate the mean difference in schistosomiasis prevalence across geopolitical zones, the relationship between schistosomiasis prevalence and livestock cattle, …
Human Service Student's Preparedness For Assessing Suicidality: Recommendations For Human Services Education, Narketta Sparkman-Key, Jeffrey Moe, Bianca Augustine, T'Airra Belcher
Human Service Student's Preparedness For Assessing Suicidality: Recommendations For Human Services Education, Narketta Sparkman-Key, Jeffrey Moe, Bianca Augustine, T'Airra Belcher
Counseling & Human Services Faculty Publications
Suicide continues to be a public health concern, with suicide rates increasing. Human service professionals are among the helping professions tasked with assessing and addressing suicidality. Despite the well-documented benefits of suicide assessment and training for those within the helping professions, there remains a dearth of literature specific to suicide prevention in the preparation of human services students. To address this gap, the current study used the SIRI-2 to assess the preparedness of human services students (n = 98) to assess and address client suicidality. Findings indicated that participants’ responses were less competent than area experts. Furthermore, student participants’ responses …
Evaluation Of Wic Online Ordering During The Covid-19 Pandemic: Evidence From An Oklahoma Grocery Store Chain, Qi Zhang, Junzhou Zhang, Kayoung Park, Chuanyi Tang
Evaluation Of Wic Online Ordering During The Covid-19 Pandemic: Evidence From An Oklahoma Grocery Store Chain, Qi Zhang, Junzhou Zhang, Kayoung Park, Chuanyi Tang
Community & Environmental Health Faculty Publications
The COVID-19 pandemic is worsening the disparities in food access in the United States. As consumers have been increasingly using grocery online ordering services to limit their exposure to the COVID-19 virus, participants of federal nutrition assistance programs lack the online benefit redemption option. With the support of the US Department of Agriculture (USDA), retailers are pilot-testing online food benefit ordering in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). By combining the Oklahoma WIC administrative data, the online ordering data from a grocery store chain in Oklahoma, and the COVID-19 data in Oklahoma, this study examines …
Crime, Illness, & Abolition: An Exploration Through The Connective Tissue Within The Pic/Mic Matrix, Laila Kent
Crime, Illness, & Abolition: An Exploration Through The Connective Tissue Within The Pic/Mic Matrix, Laila Kent
Scripps Senior Theses
This two part zine illuminates the shared mechanisms that construct and respond to ‘crime’, also define and treat illness in the US. Part 1 uncovers the status quo of our prison and health care system via the emergence of the The Prison-Industrial Complex (PIC), and The Medical-Industrial Complex (MIC). Through an exploration of the respective and overlapping histories, logics, and realities underlying the function of these systems, the mechanisms of individualism, objectification, and profiteering become strikingly clear. Part 2 breaks free of the status quo outlined in Part 1 by introducing abolition as the vision and strategy to heal from …
Utilizing Amr Surveillance Data To Analyze Trends In Escherichia Coli Antibiotic Resistance Levels In The South African Provinces Of Gauteng And The Eastern Cape, Celia Maris
Scripps Senior Theses
Antimicrobial resistant bacterial pathogens pose an ongoing threat to universal public health by causing more severe manifestations of infectious diseases, leading to an increase in healthcare expenditures and higher global mortality rates. Therefore, developing strategies to combat bacterial antimicrobial resistance (AMR) is vital for the future of human health. One promising strategy is through the utilization of AMR surveillance programs. This study focused on using AMR surveillance data from South Africa to analyze changes in Escherichia coli resistance levels to numerous antibiotics between January 2012 and December 2022 in Gauteng Province and the Eastern Cape Province. The study aimed to …
We Can Do This / Juntos Sí Podemos: A Critical Discourse Analysis Of Government-Sponsored Covid-19 Public Service Announcements (Psas) In English And Spanish, Katalina R. Peterson
We Can Do This / Juntos Sí Podemos: A Critical Discourse Analysis Of Government-Sponsored Covid-19 Public Service Announcements (Psas) In English And Spanish, Katalina R. Peterson
Scripps Senior Theses
Communication inequities are known to negatively impact people from socioeconomically and linguistically disadvantaged backgrounds during public health crises (Gomez-Aguinaga et al., 2021). In the United States, Hispanics—especially those who speak Spanish—have been among the communities most disproportionately affected by COVID-19 (National Center for Health Statistics, 2022). The pandemic has underscored the importance of understanding the linguistic and discursive strategies implemented by institutions entrusted with disseminating public health information to reach diverse audiences, especially the most vulnerable. This paper analyzes the linguistic practices used to create public service announcements (PSA) produced in English and Spanish by health agencies at both the …
The Role Of Porn Literacy In Comprehensive Sex Education To Reduce Endorsements Of Gendered Sexual Violence And Support Healthy Adolescent Development, Kiana Harnish
Scripps Senior Theses
Due to stigmatization of sex and insufficient sexual education, modern-day adolescents rely on free online pornography as a source of education about sex and relationships. This thesis provides a review of the connections between adolescent porn use and the socialization of sexual violence (SV) and coercion against women, comprehensive sex education (CSE) and healthy adolescent sexual development, and porn literacy (PL) and sexual attitude or behavior changes. Porn literacy aims to equip adolescents with tools to critically analyze sexualied media and messages, to empower them to make informed decisions to engage or disengage with porn and their sexuality in a …
Campus Sexual Violence In The Time Of Covid-L9, Hannah Holt
Campus Sexual Violence In The Time Of Covid-L9, Hannah Holt
Master’s Theses
Campus sexual assault (CSA) was likely on the rise in the United States (Koss et al., 2022) even prior to the COVID-19 pandemic, during which there was a global increase in violence against women. The present study is a needed addition to the limited rigorous scientific studies on the impact of the COVID-19 pandemic on campus sexual assault (CSA). A mixed-methods, ecological, and critical feminist approach was used to investigate CSA during the mitigation period. The present study specifically utilized the Sexual Experiences Survey (Koss et al., 2007) to assess changes in frequency of victimization within two representative samples of …
A Biblioguidance Approach To Fostering Students’ Self-Efficacy To Advocate For Health, Jennifer R. Banas, Sara Gershon
A Biblioguidance Approach To Fostering Students’ Self-Efficacy To Advocate For Health, Jennifer R. Banas, Sara Gershon
Health Sciences and Physical Education Faculty Publications
Teaching the components of health advocacy is straightforward, but fostering young people’s self-efficacy to be health advocates for themselves, others, and their community is more complex. This complexity sometimes renders advocating for health, the basis of National Health Education Standard (NHES) #8, challenging to teach. We utilized a pedagogical approach called biblioguidance to teach this skill to 10th-grade students. The premise of biblioguidance, also called bibliotherapy, is that information, guidance, and even solace can be found through reading and vicariously living story events. To implement this approach, we consulted the literature and created a six-step framework to guide the design, …
Smoking Cessation Through Optimisation Of Clinical Care In Pregnancy: The Stop Randomised Controlled Trial, Brendan P. Mcdonnell, Patrick Dicker, Sheila Keogan, Luke Clancy, Carmen Regan
Smoking Cessation Through Optimisation Of Clinical Care In Pregnancy: The Stop Randomised Controlled Trial, Brendan P. Mcdonnell, Patrick Dicker, Sheila Keogan, Luke Clancy, Carmen Regan
Articles
This is a pragmatic randomised controlled trial of a dedicated smoking cessation clinic versus routine antenatal care as an intervention to reduce cigarette smoking behaviour. Smoking mothers randomised to the Smoking cessation Through Optimisation of clinical care in Pregnancy (STOP) clinic will have all antenatal care provided by a team comprising an obstetrician, a midwife, and a smoking cessation practitioner. This intervention includes ultrasound screening for fetal growth restriction. The control arm comprises two groups: one receiving standard care with ultrasound screening for fetal growth restriction, and one receiving standard care with ultrasound screening for growth restriction only if clinically …
The Role Of Smoking In Covid-19 Progression: A Comprehensive Meta-Analysis, Silvano Gallus, Marco Scala, Irene Possenti, Carlotta Micaela Jarach, Luke Clancy, Esteve Fernandez, Giuseppe Gorini, Giulia Carreras, Maria Chiara Malevolti, Alison Commar, Ranti Fayokun, Hebe N. Gouda, Vinayak M. Prasad, Alessandra Lugo
The Role Of Smoking In Covid-19 Progression: A Comprehensive Meta-Analysis, Silvano Gallus, Marco Scala, Irene Possenti, Carlotta Micaela Jarach, Luke Clancy, Esteve Fernandez, Giuseppe Gorini, Giulia Carreras, Maria Chiara Malevolti, Alison Commar, Ranti Fayokun, Hebe N. Gouda, Vinayak M. Prasad, Alessandra Lugo
Articles
The association between current smoking and coronavirus disease 2019 (COVID-19) progression remains uncertain. We aim to provide up-to-date evidence of the role of cigarette smoking in COVID-19 hospitalisation, severity and mortality. On 23 February 2022 we conducted an umbrella review and a traditional systematic review via PubMed/Medline and Web of Science. We used random-effects meta-analyses to derive pooled odds ratios of COVID-19 outcomes for smokers in cohorts of severe acute respiratory syndrome coronavirus 2 infected individuals or COVID-19 patients. We followed the Meta-analysis of Observational Studies in Epidemiology reporting guidelines. PROSPERO: CRD42020207003. 320 publications were included. The pooled odds ratio …
Implementing Education For Maternity Nurses To Improve Nurses’ Knowledge, Attitudes, And Practices Regarding Postpartum Depression: A Quality Improvement Initiative, Haley Merrill
Master's Theses and Capstones
BACKGROUND: Postpartum depression (PPD) is the most common complication of childbirth, but often goes undiagnosed. Adequate patient education on PPD increases the patient’s knowledge and supports enhanced communication between patients and provider. Maternity nurses have continued interaction with new mothers and are in a vital position to educate patients regarding PPD. However, maternity nurses may lack confidence in delivering the appropriate education and resources for PPD to postpartum women.
LOCAL PROBLEM: Within the given microsystem, there was currently a gap that existed between PPD education for nurses and the delivery of PPD patient education.
METHODS: Utilizing the Plan-Do-Study-Act model, a …
Support Their Sleep: Enhancing Nurses' Knowledge And Implementation Of Non-Pharmacological Sleep Protocols To Improve Patient Rest, Recovery, And Reduce Cognitive Impairment., David C. Barry
Master's Theses and Capstones
Background: Sleep and rest play an influential role in promoting recovery and healing in humans. Hospitalized patients are at risk for altered sleep from hospitalization, illness, and stimulation from a hospital environment. Non-pharmacologic interventions preformed by nurses can help to improve sleep and sleep environment for patients.
Local problem: There was no protocol or available information regarding patient sleep promotion for nurses to references when caring for patients.
Methods: Nurses in the microsystem (n=8) were administered a pre/post questionnaire containing Likert scales and a short quiz containing knowledge-based questions. Questionnaires were distributed to nurses prior to and after …
School-Based Intervention Impacts Availability Of Vegetables And Beverages In Participants’ Homes, Erin A Hudson, Marissa Burgermaster, Sophia M Isis, Matthew R Jeans, Sarvenaz Vandyousefi, Matthew J Landry, Rebecca Seguin-Fowler, Joya Chandra, Jaimie Davis
School-Based Intervention Impacts Availability Of Vegetables And Beverages In Participants’ Homes, Erin A Hudson, Marissa Burgermaster, Sophia M Isis, Matthew R Jeans, Sarvenaz Vandyousefi, Matthew J Landry, Rebecca Seguin-Fowler, Joya Chandra, Jaimie Davis
Faculty, Staff and Student Publications
As rates of metabolic syndrome rise, children consume too few vegetables and too much added sugar. Because children tend to eat what is available at home, the home environment plays a key role in shaping dietary habits. This secondary analysis evaluated the effects of a school-based gardening, cooking, and nutrition education intervention (TX Sprouts) compared to control on the availability of vegetables, fruit juice, and sugar-sweetened beverages (SSBs) at home. In the TX Sprouts cluster-randomized trial, 16 schools were randomized to TX Sprouts (
Optimization Of Mesh Generation For Geometric Accuracy, Robustness, And Efficiency Of Biomechanical-Model-Based Deformable Image Registration, Yulun He, Brian M Anderson, Guillaume Cazoulat, Bastien Rigaud, Lusmeralis Almodovar-Abreu, Julianne Pollard-Larkin, Peter Balter, Zhongxing Liao, Radhe Mohan, Bruno Odisio, Stina Svensson, Kristy K Brock
Optimization Of Mesh Generation For Geometric Accuracy, Robustness, And Efficiency Of Biomechanical-Model-Based Deformable Image Registration, Yulun He, Brian M Anderson, Guillaume Cazoulat, Bastien Rigaud, Lusmeralis Almodovar-Abreu, Julianne Pollard-Larkin, Peter Balter, Zhongxing Liao, Radhe Mohan, Bruno Odisio, Stina Svensson, Kristy K Brock
Faculty, Staff and Student Publications
BACKGROUND: Successful generation of biomechanical-model-based deformable image registration (BM-DIR) relies on user-defined parameters that dictate surface mesh quality. The trial-and-error process to determine the optimal parameters can be labor-intensive and hinder DIR efficiency and clinical workflow.
PURPOSE: To identify optimal parameters in surface mesh generation as boundary conditions for a BM-DIR in longitudinal liver and lung CT images to facilitate streamlined image registration processes.
METHODS: Contrast-enhanced CT images of 29 colorectal liver cancer patients and end-exhale four-dimensional CT images of 26 locally advanced non-small cell lung cancer patients were collected. Different combinations of parameters that determine the triangle mesh quality …
Extreme Temperatures And Sickness Absence In The Mediterranean Province Of Barcelona: An Occupational Health Issue, Mireia Utzet, Amaya Ayala-Garcia, Fernando G Benavides, Xavier Basagaña
Extreme Temperatures And Sickness Absence In The Mediterranean Province Of Barcelona: An Occupational Health Issue, Mireia Utzet, Amaya Ayala-Garcia, Fernando G Benavides, Xavier Basagaña
Faculty, Staff and Student Publications
OBJECTIVES: This study aims to assess the association between daily temperature and sickness absence episodes in the Mediterranean province of Barcelona between 2012 and 2015, according to sociodemographic and occupational characteristics.
METHODS: Ecological study of a sample of salaried workers affiliated to the Spanish social security, resident in Barcelona province between 2012 and 2015. The association between daily mean temperature and risk of new sickness absence episodes was estimated with distributed lag non-linear models. The lag effect up to 1 week was considered. Analyses were repeated separately by sex, age groups, occupational category, economic sector and medical diagnosis groups of …
Workplace Aggression Against Healthcare Workers In A Spanish Healthcare Institution Between 2019 And 2021: The Impact Of The Covid-19 Pandemic, Aitor Díaz, Mireia Utzet, Joan Mirabent, Pilar Diaz, Jose Maria Ramada, Consol Serra, Fernando G Benavides
Workplace Aggression Against Healthcare Workers In A Spanish Healthcare Institution Between 2019 And 2021: The Impact Of The Covid-19 Pandemic, Aitor Díaz, Mireia Utzet, Joan Mirabent, Pilar Diaz, Jose Maria Ramada, Consol Serra, Fernando G Benavides
Faculty, Staff and Student Publications
OBJECTIVES: Describe the incidence of first aggressions among healthcare workers (HCWs) before and during the COVID-19 pandemic in a Spanish healthcare institution, according to workers' socio-occupational characteristics and analyze the impact of the pandemic on it.
METHODS: A cohort involving HCWs who worked in the institution for at least 1 week each year from 1 January 2019 to 31 December 2021. Adjusted relative risks (aRR) were estimated using generalized estimating equations and negative binomial models to calculate the differences in WPA between the different time periods. All analyses were stratified by gender.
RESULTS: Among women, the incidence was 6.8% (6.0; …
Plasma Enzymatic Activity, Proteomics And Peptidomics In Covid-19-Induced Sepsis: A Novel Approach For The Analysis Of Hemostasis, Fernando Dos Santos, Joyce B Li, Nathalia Juocys, Rafi Mazor, Laura Beretta, Nicole G Coufal, Michael T Y Lam, Mazen F Odish, Maria Claudia Irigoyen, Anthony J O'Donoghue, Federico Aletti, Erik B Kistler
Plasma Enzymatic Activity, Proteomics And Peptidomics In Covid-19-Induced Sepsis: A Novel Approach For The Analysis Of Hemostasis, Fernando Dos Santos, Joyce B Li, Nathalia Juocys, Rafi Mazor, Laura Beretta, Nicole G Coufal, Michael T Y Lam, Mazen F Odish, Maria Claudia Irigoyen, Anthony J O'Donoghue, Federico Aletti, Erik B Kistler
Faculty, Staff and Student Publications
Introduction: Infection by SARS-CoV-2 and subsequent COVID-19 can cause viral sepsis. We investigated plasma protease activity patterns in COVID-19-induced sepsis with bacterial superinfection, as well as plasma proteomics and peptidomics in order to assess the possible implications of enhanced proteolysis on major protein systems (e.g., coagulation). Methods: Patients (=4) admitted to the intensive care units (ICUs) at the University of California, San Diego (UCSD) Medical Center with confirmed positive test for COVID-19 by real-time reverse transcription polymerase chain reaction (RT-PCR) were enrolled in a study approved by the UCSD Institutional Review Board (IRB# 190699, Protocol #20-0006). Informed consent was obtained …
Annotation And Information Extraction Of Consumer-Friendly Health Articles For Enhancing Laboratory Test Reporting, Zhe He, Shubo Tian, Arslan Erdengasileng, Karim Hanna, Yang Gong, Zhan Zhang, Xiao Luo, Mia Liza A Lustria
Annotation And Information Extraction Of Consumer-Friendly Health Articles For Enhancing Laboratory Test Reporting, Zhe He, Shubo Tian, Arslan Erdengasileng, Karim Hanna, Yang Gong, Zhan Zhang, Xiao Luo, Mia Liza A Lustria
Faculty, Staff and Student Publications
Viewing laboratory test results is patients' most frequent activity when accessing patient portals, but lab results can be very confusing for patients. Previous research has explored various ways to present lab results, but few have attempted to provide tailored information support based on individual patient's medical context. In this study, we collected and annotated interpretations of textual lab result in 251 health articles about laboratory tests from AHealthyMe.com. Then we evaluated transformer-based language models including BioBERT, ClinicalBERT, RoBERTa, and PubMedBERT for recognizing key terms and their types. Using BioPortal's term search API, we mapped the annotated terms to concepts in …
Analysis Of Nurse And Patient Preferences For Pre-Filled Pen Devices For Self-Injection Of Highly Purified Human Menopausal Gonadotropin (Hp-Hmg, Menopurr, Guy De Mesmaeker, Brigitte Calles, Judith A Smith
Analysis Of Nurse And Patient Preferences For Pre-Filled Pen Devices For Self-Injection Of Highly Purified Human Menopausal Gonadotropin (Hp-Hmg, Menopurr, Guy De Mesmaeker, Brigitte Calles, Judith A Smith
Faculty, Staff and Student Publications
PURPOSE: This study aimed to identify the most important attributes for a gonadotropin pen as perceived by assisted reproductive technology (ART) patients and fertility nurses, and to examine how well a prototype HP-hMG (MENOPUR
PATIENTS AND METHODS: This market research study incorporated a two-part survey with respondents (N=221) from Poland, Spain and the UK. Respondents included patients (n=141) who consulted a fertility specialist in the previous 2 years, and fertility nurses (n=80) who assisted in at least 75 ART cycles/year. Patients were divided into two subgroups depending on their experience with ART (experienced and naïve). Key attributes for an injection …
Selinexor In Combination With Weekly Paclitaxel In Patients With Metastatic Solid Tumors: Results Of An Open Label, Single-Center, Multi-Arm Phase 1b Study With Expansion Phase In Ovarian Cancer, Shannon N Westin, Siqing Fu, Apostolia Tsimberidou, Sarina Piha-Paul, Fechukwu Akhmedzhanov, Bulent Yilmaz, Lacey Mcquinn, Amanda L Brink, Jing Gong, Cheuk Hong Leung, Heather Lin, David S Hong, Shubham Pant, Brett Carter, Amir Jazaeri, David Gershenson, Anil K Sood, Robert L Coleman, Jatin Shah, Funda Meric-Bernstam, Aung Naing
Selinexor In Combination With Weekly Paclitaxel In Patients With Metastatic Solid Tumors: Results Of An Open Label, Single-Center, Multi-Arm Phase 1b Study With Expansion Phase In Ovarian Cancer, Shannon N Westin, Siqing Fu, Apostolia Tsimberidou, Sarina Piha-Paul, Fechukwu Akhmedzhanov, Bulent Yilmaz, Lacey Mcquinn, Amanda L Brink, Jing Gong, Cheuk Hong Leung, Heather Lin, David S Hong, Shubham Pant, Brett Carter, Amir Jazaeri, David Gershenson, Anil K Sood, Robert L Coleman, Jatin Shah, Funda Meric-Bernstam, Aung Naing
Faculty, Staff and Student Publications
OBJECTIVE: Selinexor is a first-in-class, oral selective inhibitor of nuclear export (SINE) compound which blocks Exportin-1 (XPO1). Our objective was to determine maximum tolerated dose (MTD) and recommended phase II dose (RP2D) of selinexor and weekly paclitaxel.
METHODS: This was an open label, single-center, multi-arm phase 1b study utilizing a "3 + 3" design and a "basket-type" expansion in recurrent solid tumors. Selinexor (60 mg or 80 mg twice weekly orally) and weekly paclitaxel (80 mg IV 2 week on, 1 week off) were one of 13 parallel arms. Efficacy was evaluated using RECIST version 1.1.
RESULTS: All 35 patients …
View-Sharing For 4d Magnetic Resonance Imaging With Randomized Projection-Encoding Enables Improvements Of Respiratory Motion Imaging For Treatment Planning In Abdominothoracic Radiotherapy, Ergys Subashi, Li Feng, Yilin Liu, Scott Robertson, Paul Segars, Bastiaan Driehuys, Christopher R Kelsey, Fang-Fang Yin, Ricardo Otazo, Jing Cai
View-Sharing For 4d Magnetic Resonance Imaging With Randomized Projection-Encoding Enables Improvements Of Respiratory Motion Imaging For Treatment Planning In Abdominothoracic Radiotherapy, Ergys Subashi, Li Feng, Yilin Liu, Scott Robertson, Paul Segars, Bastiaan Driehuys, Christopher R Kelsey, Fang-Fang Yin, Ricardo Otazo, Jing Cai
Faculty, Staff and Student Publications
BACKGROUND AND PURPOSE: The accuracy and precision of radiation therapy are dependent on the characterization of organ-at-risk and target motion. This work aims to demonstrate a 4D magnetic resonance imaging (MRI) method for improving spatial and temporal resolution in respiratory motion imaging for treatment planning in abdominothoracic radiotherapy.
MATERIALS AND METHODS: The spatial and temporal resolution of phase-resolved respiratory imaging is improved by considering a novel sampling function based on quasi-random projection-encoding and peripheral k-space view-sharing. The respiratory signal is determined directly from k-space, obviating the need for an external surrogate marker. The average breathing curve is used to optimize …