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Full-Text Articles in Public Health

Analisis Faktor Risiko Kejadian Stunted, Underweight, Dan Wasted Pada Balita Di Wilayah Kerja Puskesmas Rangkapan Jaya, Kota Depok, Jawa Barat Tahun 2022, Anggi Tria Abimayu, Nurul Dina Rahmawati Mar 2023

Analisis Faktor Risiko Kejadian Stunted, Underweight, Dan Wasted Pada Balita Di Wilayah Kerja Puskesmas Rangkapan Jaya, Kota Depok, Jawa Barat Tahun 2022, Anggi Tria Abimayu, Nurul Dina Rahmawati

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Menurut UNICEF, status gizi pada anak secara langsung dipengaruhi oleh asupan makanan dan infeksi penyakit. Namun, banyak faktor secara tidak langsung yang mempengaruhi tumbuh kembang anak, diantaranya berat lahir, panjang lahir, jenis kelamin, usia dan status kenaikan berat badan. Maka dari itu penelitian ini bertujuan untuk menganalisis hubungan antara faktor risiko tersebut dengan kejadian stunted, underweight dan wasted. Metode yang digunakan adalah cross sectional dengan menggunakan data sekunder dari website Elektronik Pencatatan dan Pelaporan Gizi Berbasis Masyarakat (E PPGBM). Hasil dari penelitian ini adalah adanya hubungan berat lahir, panjang lahir, jenis kelamin, usia dan status kenaikan berat badan dengan …


Faktor-Faktor Terjadinya Kematian Neonatal Di Indonesia: Analisis Data Sdki 2017, Mochtar Ghaffar Ramadhan, Ulya Qoulan Karima, Terry Yuliana, Chahya Kharin Herbawani Mar 2023

Faktor-Faktor Terjadinya Kematian Neonatal Di Indonesia: Analisis Data Sdki 2017, Mochtar Ghaffar Ramadhan, Ulya Qoulan Karima, Terry Yuliana, Chahya Kharin Herbawani

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Kematian neonatal merupakan masalah yang harus diselesaikan dalam SDGs. Sama halnya di Indonesia, masih adanya ketimpangan antara target RPJMN 2020-2024 untuk menurunkan angka kematian neonatal menjadi 10 per 1000 kelahiran hidup. Penelitian ini bertujuan untuk mengetahui faktor-faktor terjadinya kematian neonatal di Indonesia sebagai salah satu cara untuk mencapai target RPJMN. Penelitian ini menggunakan desain studi potong lintang dengan analisis data sekunder SDKI 2017. Sampel yang digunakan penelitian ini adalah 34.972 wanita usia subur usia 15-49 tahun yang pernah melahirkan di Indonesia. Analisis menggunakan pembobotan dan analisis yang digunakan adalah analisis spasial, Chi-Square, dan regresi logistik ganda. Hasil analisis bivariat menunjukkan …


Pengelompokan Provinsi Di Indonesia Berdasarkan Faktor Risiko Perilaku Penyakit Tidak Menular Dengan Metric Multidimensional Scaling, Syafira Maulidia, Rahmi Susanti, Ismail Ab Mar 2023

Pengelompokan Provinsi Di Indonesia Berdasarkan Faktor Risiko Perilaku Penyakit Tidak Menular Dengan Metric Multidimensional Scaling, Syafira Maulidia, Rahmi Susanti, Ismail Ab

Jurnal Biostatistik, Kependudukan, dan Informatika Kesehatan

Angka kasus penyakit tidak menular (PTM) di Indonesia terus mengalami peningkatan. Faktor pendorong utama terjadinya peningkatan PTM adalah dari faktor risiko perilaku yaitu, pengunaan tembakau, penggunaan alkohol, aktivitas fisik, dan diet tidak sehat. Berdasarkan hal tersebut diperlukan pengelompokan provinsi di Indonesia berdasarkan faktor risiko perilaku PTM. Menghasilkan kelompok-kelompok provinsi di Indonesia berdasarkan faktor risiko perilaku PTM. Jenis penelitian ini adalah non-reactive research. Pengelompokan provinsi di Indonesia menggunakan analisis Metric Multidimensional Scaling dan analisis One Way MANOVA sebagai analisis lanjutan untuk memvalidasi perbedaan kelompok yang dibentuk. Data yang digunakan merupakan data sekunder dari publikasi laporan Riset Kesehatan Dasar Indonesia tahun …


Ad-Syn-Net: Systematic Identification Of Alzheimer's Disease-Associated Mutation And Co-Mutation Vulnerabilities Via Deep Learning, Xingxin Pan, Zeynep H Coban Akdemir, Ruixuan Gao, Xiaoqian Jiang, Gloria M Sheynkman, Erxi Wu, Jason H Huang, Nidhi Sahni, S Stephen Yi Mar 2023

Ad-Syn-Net: Systematic Identification Of Alzheimer's Disease-Associated Mutation And Co-Mutation Vulnerabilities Via Deep Learning, Xingxin Pan, Zeynep H Coban Akdemir, Ruixuan Gao, Xiaoqian Jiang, Gloria M Sheynkman, Erxi Wu, Jason H Huang, Nidhi Sahni, S Stephen Yi

Faculty, Staff and Student Publications

Alzheimer's disease (AD) is one of the most challenging neurodegenerative diseases because of its complicated and progressive mechanisms, and multiple risk factors. Increasing research evidence demonstrates that genetics may be a key factor responsible for the occurrence of the disease. Although previous reports identified quite a few AD-associated genes, they were mostly limited owing to patient sample size and selection bias. There is a lack of comprehensive research aimed to identify AD-associated risk mutations systematically. to address this challenge, we hereby construct a large-scale AD mutation and co-mutation framework ('AD-Syn-Net'), and propose deep learning models named Deep-SMCI and Deep-CMCI configured …


Sources Of Stress, Burnout, And Career Decisions Of Male Health And Nursing Professionals: A Qualitative Inquiry Of The Challenges During The Covid-19 Pandemic, Luis Miguel Dos Santos Mar 2023

Sources Of Stress, Burnout, And Career Decisions Of Male Health And Nursing Professionals: A Qualitative Inquiry Of The Challenges During The Covid-19 Pandemic, Luis Miguel Dos Santos

The Qualitative Report

The human resources and workforce shortage of registered health and nursing professionals has been a long-term problem in health systems internationally, particularly during the COVID-19 pandemic. Many health and nursing professionals face stress and burnout, which may influence their career decisions and long-term human resources development. The purpose of this study is to investigate and understand the relationship(s) between sources of stress and the reasons why male health and nursing professionals decide to leave the profession within the next six months. With the employment of the social cognitive career and motivation theory and general inductive approach with 40 male health …


Supporting Caregivers Of The Aging Adult: A Program Evaluation, Tanya O'Brien Mar 2023

Supporting Caregivers Of The Aging Adult: A Program Evaluation, Tanya O'Brien

Student Scholarly Projects

There is an ever-increasing burden on caregivers of individuals with cognitive illness as a result of the increasing number of older adults with dementia and Alzheimer's disease. Currently, St. John's County Florida offers three programs designed to provide support for caregivers of individuals with cognitive illness. This project evaluated the three programs as part of a program evaluation to determine the efficacy of program selection for sustainability. Utilizing the Center for Disease Control's (CDC) Program Evaluation Framework (PEF), a detailed and thorough evaluation review of the Power Tools for Caregivers, Savvy Caregiver, and an original three-model program developed by the …


Associations Of Physical Inactivity And Covid-19 Outcomes Among Subgroups, Gary N. Smith, Deborah Rohm Young, James F. Sallis, Aileen Baecker, Deborah A. Cohen, Robert E. Sallis, Claudia L. Nau Mar 2023

Associations Of Physical Inactivity And Covid-19 Outcomes Among Subgroups, Gary N. Smith, Deborah Rohm Young, James F. Sallis, Aileen Baecker, Deborah A. Cohen, Robert E. Sallis, Claudia L. Nau

Pomona Faculty Publications and Research

Selected as the AJPM paper of the year. This paper reports additional evidence that regular physical exercise prior to COVID infection substantially reduces the chances of hospitalization, admission to intensive care units, and death.


2023-03-17_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services Mar 2023

2023-03-17_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.


The Association Between Medication Use In Older Women With Early-Stage Operable Primary Breast Cancer And Decision Regarding Primary Treatment, Natalie Tse, Ruth M Parks, Holly M Holmes, Kwok-Leung Cheung Mar 2023

The Association Between Medication Use In Older Women With Early-Stage Operable Primary Breast Cancer And Decision Regarding Primary Treatment, Natalie Tse, Ruth M Parks, Holly M Holmes, Kwok-Leung Cheung

Faculty, Staff and Student Publications

Background: Polypharmacy is one factor contributing to increased mortality, hospitalization, and adverse drug reactions in older adults. The aim of this study was to measure the prevalence of polypharmacy in a cohort of older women with early-stage operable primary breast cancer and the relationship of polypharmacy to primary treatment decision and functional status.

Methods: A total of 139 patients with a new diagnosis of early-stage operable primary breast cancer proven histologically were recruited as part of a prospective study. The average age was 77 years. Assessment using a cancer-specific Comprehensive Geriatric Assessment (CGA) tool was conducted within 6 weeks of …


Global Scientific Trends On Healthy Eating From 2002 To 2021: A Bibliometric And Visualized Analysis, Te Fang, Hongyi Cao, Yue Wang, Yang Gong, Zhongqing Wang Mar 2023

Global Scientific Trends On Healthy Eating From 2002 To 2021: A Bibliometric And Visualized Analysis, Te Fang, Hongyi Cao, Yue Wang, Yang Gong, Zhongqing Wang

Faculty, Staff and Student Publications

Diet has been recognized as a vital risk factor for non-communicable diseases (NCDs), climate changes, and increasing population, which has been reflected by a rapidly growing body of the literature related to healthy eating. To reveal a panorama of the topics related to healthy eating, this study aimed to characterize and visualize the knowledge structure, hotspots, and trends in this field over the past two decades through bibliometric analyses. Publications related to healthy eating between 1 January 2002 and 31 December 2021 were retrieved and extracted from the Web of Science database. The characteristics of articles including publication years, journals, …


2023-03-16 Michiganoverview_Covidoutbreak, Michigan Department Of Health & Human Services Mar 2023

2023-03-16 Michiganoverview_Covidoutbreak, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

The Outbreak Data page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/stats/outbreak-reporting.

This report is created by the Michigan Department of Health & Human Services from data self-reported by local health departments. Data is updated every week.

COVID-19 outbreaks are generally defined as two or more cases with a link by place and time indicating a shared exposure outside of a household. Local health departments report the number of new and ongoing outbreaks they are investigating by the setting of the outbreak. New outbreaks are those outbreaks that were first identified during the current reporting week. Ongoing outbreaks are …


Risk-Reduction Research In Occupational Safety And Ergonomics: An Editorial, Roger C. Jensen, David P. Gilkey Mar 2023

Risk-Reduction Research In Occupational Safety And Ergonomics: An Editorial, Roger C. Jensen, David P. Gilkey

Safety Health & Industrial Hygiene

Occupational health and safety is one of the pillars of public health. The magnitude of occupational injuries, illnesses, and fatalities has been well documented through retrospective analyses of existing record systems. This Special Issue in IJERPH sought research papers addressing risk reduction studies in occupational safety and ergonomics.


2023-03-16_Michiganoverview_Misc, Michigan Department Of Health & Human Services Mar 2023

2023-03-16_Michiganoverview_Misc, Michigan Department Of Health & Human Services

Michigan COVID-19 MIS-C Data

The MIS-C Data page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/stats/mis-c-reporting.

This report is created by the Michigan Department of Health & Human Services from data self-reported by health care providers and local health departments. Data is updated on the first and third Thursdays of the month.

Multisystem Inflammatory Syndrome in Children (MIS-C) is a condition in children and adolescents under 21 years of age where multiple organ systems become inflamed or dysfunctional which occurs in association with illness. Children with MIS-C may have a fever and various symptoms, including abdominal (gut) pain, vomiting, diarrhea, neck pain, rash, …


A Scoping Review Of Digital Health Interventions For Combating Covid-19 Misinformation And Disinformation, Katarzyna Czerniak, Raji Pillai, Abhi Parmar, Kavita Ramnath, Joseph Krocker, Sahiti Myneni Mar 2023

A Scoping Review Of Digital Health Interventions For Combating Covid-19 Misinformation And Disinformation, Katarzyna Czerniak, Raji Pillai, Abhi Parmar, Kavita Ramnath, Joseph Krocker, Sahiti Myneni

Faculty, Staff and Student Publications

OBJECTIVE: We provide a scoping review of Digital Health Interventions (DHIs) that mitigate COVID-19 misinformation and disinformation seeding and spread.

MATERIALS AND METHODS: We applied our search protocol to PubMed, PsychINFO, and Web of Science to screen 1666 articles. The 17 articles included in this paper are experimental and interventional studies that developed and tested public consumer-facing DHIs. We examined these DHIs to understand digital features, incorporation of theory, the role of healthcare professionals, end-user experience, and implementation issues.

RESULTS: The majority of studies (n = 11) used social media in DHIs, but there was a lack of platform-agnostic generalizability. …


Patient Perspectives On Noninvasive Prenatal Testing Among Black Women In The United States: A Scoping Review, Shameka P. Thomas, Madison A. Keller, Tiara Ranson, Rachele E. Willard Mar 2023

Patient Perspectives On Noninvasive Prenatal Testing Among Black Women In The United States: A Scoping Review, Shameka P. Thomas, Madison A. Keller, Tiara Ranson, Rachele E. Willard

School of Medicine Faculty Publications

Advances in reproductive health technologies such as noninvasive prenatal testing (NIPT) are changing the landscape of prenatal care and maternal health. NIPT, made clinically available in the United States (US) in 2011, is a screening test that utilizes cell-free DNA (cfDNA) to detect for aneuploidies and genetic characteristics in fetal DNA. In September 2020, the American College of Obstetricians and Gynecologists (ACOG) recommended NIPT for all pregnant patients regardless of age or risk factors. We examined peer-reviewed, empirical studies published from January 2011 to February 2022, assessing NIPT studies with patient perspectives in the US and what is known about …


Using The Genetic Counseling Skills Checklist To Characterize Prenatal Genetic Counseling, David A. Cline Mar 2023

Using The Genetic Counseling Skills Checklist To Characterize Prenatal Genetic Counseling, David A. Cline

USF Tampa Graduate Theses and Dissertations

Genetic Counseling relies on communication skills to help patients understand and adapt to a genetic disease or risk. However, little is known about which skills are most commonly used or the extent to which genetic counseling sessions vary. A novel process measure titled the "Genetic Counseling Skills Checklist" (GCSC) was developed in a prior pilot study and includes 8 broad categories each consisting of 5-8 skills. This study is the first to apply the final GCSC to characterize 20 mock prenatal sessions conducted by 5 genetic counselors (GCs) for 2 prenatal indications using 3 trained actors as patients. Two experienced …


How Have Researchers Defined Institutions, Politics, Organizations And Governance In Research Related To Epidemic And Pandemic Response? A Scoping Review To Map Current Concepts, Austin Wu, Shivangi Khanna, Shelly Keidar, Peter Berman, Laura Jane Brubacher Mar 2023

How Have Researchers Defined Institutions, Politics, Organizations And Governance In Research Related To Epidemic And Pandemic Response? A Scoping Review To Map Current Concepts, Austin Wu, Shivangi Khanna, Shelly Keidar, Peter Berman, Laura Jane Brubacher

Faculty, Staff and Student Publications

In recent years, the literature on public health interventions and health outcomes in the context of epidemic and pandemic response has grown immensely. However, relatively few of these studies have situated their findings within the institutional, political, organizational and governmental (IPOG) context in which interventions and outcomes exist. This conceptual mapping scoping study synthesized the published literature on the impact of IPOG factors on epidemic and pandemic response and critically examined definitions and uses of the terms IPOG in this literature. This research involved a comprehensive search of four databases across the social, health and biomedical sciences as well as …


2023-03-15 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services Mar 2023

2023-03-15 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.


2023-03-15_Michiganoverview_Covidvaccinestats, Michigan Department Of Health & Human Services Mar 2023

2023-03-15_Michiganoverview_Covidvaccinestats, Michigan Department Of Health & Human Services

Michigan COVID-19 Vaccine Data

The COVID Vaccine Dashboard page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/resources/covid-19-vaccine/covid-19-dashboard.

First-dose tracker above is for entire Michigan Population. Coverage maps below are for age 5+.

Previously reported numbers of administered vaccine doses may change as new data are received. A possible lag in reporting vaccine doses will result in increases in numbers previously reported.

This report is created by the Michigan Department of Health and Human Services Division of Immunization from data reported to the Michigan Care Improvement Registry (MCIR).

The dashboard contained the tabs Primary Series Doses Administered, Primary Series Doses by Vaccine, …


2023-03-14_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services Mar 2023

2023-03-14_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was downloaded as an Excel spreadsheet which appeared in the Public Use Datasets section under the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/stats.

Cases are aggregated by the date of onset of COVID-19 symptoms, if known, otherwise by laboratory specimen date if known, otherwise by case referral date. Deaths are aggregated by the date of death if known, otherwise by the last date of a change to the case status.


2023-03-14_Michiganoverview_Isdreporting, Michigan Department Of Health & Human Services Mar 2023

2023-03-14_Michiganoverview_Isdreporting, Michigan Department Of Health & Human Services

Michigan COVID-19 Outbreak Reports

The K-12 Aged ISD Reporting page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/stats/k-to-12-aged-isd-reporting.

This report is created from data reported by the Michigan Disease Surveillance System (MDSS) the Michigan Department of Health and Human Services' web-based communicable disease reporting system. Data is updated every week.

The purpose of the dashboard is to report the 7 day average of COVID-19 cases in Michigan school students aged 5 through 18 at the intermediate school district and school district levels, as well as display trends over time to better illustrate the changing nature of the COVID-19 pandemic. Cases are attributed to …


2023-03-14_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services Mar 2023

2023-03-14_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/stats.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted once a week on Tuesdays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) …


2023-03-14_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services Mar 2023

2023-03-14_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/stats/data-about-places/long-term-care-data.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data for all reporting facilities is posted weekly each Monday.

The information below represents COVID-19 data reported directly to MDHHS by licensed and operating Skilled Nursing, Home for the Aged and Adult Foster Care facilities (licensed to serve 13 or more individuals) in Michigan from January 1, 2020. All long-term care facilities additionally have an obligation to report COVID-positive residents and/or staff …


Relationship Between Treatment Comorbidities And Hiv Viral Suppression Among People Who Live With Aids In Johannesburg., Nwogo Immaculata Ekeji, Tolulope A. Osoba, Hebatullah Tawfik, Mehdi Agha Mar 2023

Relationship Between Treatment Comorbidities And Hiv Viral Suppression Among People Who Live With Aids In Johannesburg., Nwogo Immaculata Ekeji, Tolulope A. Osoba, Hebatullah Tawfik, Mehdi Agha

Journal of Social, Behavioral, and Health Sciences

HIV has globally infected over 37.9 million people, of which 28.2 million (73%) are on antiretroviral treatment, and 66% of those on treatment are virally suppressed. In South Africa, however, low rate of viral suppression (47%) among people living with HIV is a major health problem that has continued to fuel HIV prevalence. A cross-sectional quantitative research design was used to investigate the relationship between treatment comorbidities and viral suppression among HIV-infected adults aged 18–49 who were diabetic, had cancer, or tuberculosis in Johannesburg. HIV Care Continuum formed the theoretical framework for this research. An existing HIV-infected patient de-identifiable dataset …


Shedding Light On Mechanisms Of Myocarditis With Covid-19 Mrna Vaccines, Biykem Bozkurt Mar 2023

Shedding Light On Mechanisms Of Myocarditis With Covid-19 Mrna Vaccines, Biykem Bozkurt

Faculty, Staff and Students Publications

No abstract provided.


Innovative Research Framework For Strengthening Health Care And Public Health Engagement In Neighborhood Change As A Social Determinant Of Health, Christopher Williams, Nathaniel Woodard, Charlene Chao-Li Kuo Mar 2023

Innovative Research Framework For Strengthening Health Care And Public Health Engagement In Neighborhood Change As A Social Determinant Of Health, Christopher Williams, Nathaniel Woodard, Charlene Chao-Li Kuo

Advances in Clinical Medical Research and Healthcare Delivery

Background

Neighborhood change is a social determinant of health (SDOH) that has been associated with adverse health and increased health care utilization. The number of cities and neighborhoods undergoing intense gentrification, defined as an influx of wealthy populations into a working-class neighborhood, is not highly numerous. Public health and health systems are increasingly engaged with SDOH in community-level interventions. Pathways to study and affect NC-related health impacts are limited. This unfunded study provides a research framework to address concerns about financial investment, identifying population health needs, and community stakeholder engagement.

Methods

The authors conducted a cross-sectional pilot study in a …


Telemedicine, Not The Panacea We Thought It Would Be. A Tale Of Caution, Ahmed Elkhapery, Syed Faiz Abbas, Basil George Verghese Mar 2023

Telemedicine, Not The Panacea We Thought It Would Be. A Tale Of Caution, Ahmed Elkhapery, Syed Faiz Abbas, Basil George Verghese

Advances in Clinical Medical Research and Healthcare Delivery

In the last few decades, the growing use of telemedicine has allowed access to healthcare at reduced costs and increased monitoring of chronic conditions, especially in underserved and rural areas. It is a tool of great value in low-income countries where there is a paucity of specialists. In the height of the COVID-19 pandemic, telemedicine was used to screen patients with COVID-19 like symptoms and send them to test sites directly. This helped minimize unnecessary healthcare staff and patient exposure to the infection and helped decompress ERs. Due to a lack of testing resources, many mildly symptomatic patients were presumed …


2023-03-13 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services Mar 2023

2023-03-13 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.


The P323l Substitution In The Sars-Cov-2 Polymerase (Nsp12) Confers A Selective Advantage During Infection, Hannah Goldswain, Xiaofeng Dong, Rebekah Penrice-Randal, Muhannad Alruwaili, Ghada T Shawli, Tessa Prince, Maia Kavanagh Williamson, Jayna Raghwani, Nadine Randle, Benjamin Jones, I'Ah Donovan-Banfield, Francisco J Salguero, Julia A Tree, Yper Hall, Catherine Hartley, Maximilian Erdmann, James Bazire, Tuksin Jearanaiwitayakul, Malcolm G Semple, Peter J M Openshaw, J Kenneth Baillie, Isaric4c Investigators, Stevan R Emmett, Paul Digard, David A Matthews, Lance Turtle, Alistair C Darby, Andrew D Davidson, Miles W Carroll, Julian A Hiscox Mar 2023

The P323l Substitution In The Sars-Cov-2 Polymerase (Nsp12) Confers A Selective Advantage During Infection, Hannah Goldswain, Xiaofeng Dong, Rebekah Penrice-Randal, Muhannad Alruwaili, Ghada T Shawli, Tessa Prince, Maia Kavanagh Williamson, Jayna Raghwani, Nadine Randle, Benjamin Jones, I'Ah Donovan-Banfield, Francisco J Salguero, Julia A Tree, Yper Hall, Catherine Hartley, Maximilian Erdmann, James Bazire, Tuksin Jearanaiwitayakul, Malcolm G Semple, Peter J M Openshaw, J Kenneth Baillie, Isaric4c Investigators, Stevan R Emmett, Paul Digard, David A Matthews, Lance Turtle, Alistair C Darby, Andrew D Davidson, Miles W Carroll, Julian A Hiscox

Faculty, Staff and Student Publications

BACKGROUND: The mutational landscape of SARS-CoV-2 varies at the dominant viral genome sequence and minor genomic variant population. During the COVID-19 pandemic, an early substitution in the genome was the D614G change in the spike protein, associated with an increase in transmissibility. Genomes with D614G are accompanied by a P323L substitution in the viral polymerase (NSP12). However, P323L is not thought to be under strong selective pressure.

RESULTS: Investigation of P323L/D614G substitutions in the population shows rapid emergence during the containment phase and early surge phase during the first wave. These substitutions emerge from minor genomic variants which become dominant …


Male Hormonal Contraceptives: Associations Between Students’ Perception Of And Trust In Usage And Endorsement Of Gender Norms, Zoe Keese Mar 2023

Male Hormonal Contraceptives: Associations Between Students’ Perception Of And Trust In Usage And Endorsement Of Gender Norms, Zoe Keese

Honors Program: Senior Projects (Public)

As clinical trials continue to test the safety and efficacy of new male contraceptive options, evaluating attitudes towards them is critical in expanding access to reproductive healthcare. The present study sought to investigate the relationship of endorsement of traditional masculine and feminine gender norms with attitudes towards male hormonal contraceptive pills. Using a Qualtrics survey, 45 participants rated their attitudes towards different measures, including attitude towards the male contraceptive pill, willingness to use male hormonal contraception, and endorsement of traditional masculine and feminine gender norms. The results of the survey indicated that there was a significant positive correlation between endorsing …