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Articles 6001 - 6030 of 6078

Full-Text Articles in Surgery

Method For Employing The Delta Opioid Dadle To Extend Tissue Survival Time During Ischemia, Sufan Chien Aug 1997

Method For Employing The Delta Opioid Dadle To Extend Tissue Survival Time During Ischemia, Sufan Chien

Surgery Faculty Patents

This invention concerns a method for extending the survival time of mammalian lung tissue subjected to ischemia, by which said tissue is perfused with a preservation solution comprising a therapeutic dose of the delta opioid DADLE ([D-Ala2,D-Leu5]-Enkephalin) under hypothermic conditions.

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Fine Needle Aspiration Cytology In Parotid Lumps, A Zafar, M Shafi, S H. Hassan, S Malik Jul 1997

Fine Needle Aspiration Cytology In Parotid Lumps, A Zafar, M Shafi, S H. Hassan, S Malik

Section of Otolaryngology, Head & Neck Surgery

Over a period of two years, Fine Needle Aspiration Cytology (FNAC) was performed on 33 patients presenting with a parotid lump. Five patients were excluded as they were treated medically after FNAC report. The FNAC results of 28 cases were compared with histopathological diagnoses of surgically resected specimens. There were 8 true positive, 17 true negative, 1 false positive and 2 false negative cases. Sensitivity was 80%, specificity 94.4% and diagnostic accuracy 89.3%. FNAC is a simple quick, accurate and virtually complications free investigative modality. It is also helpful adjunct to assess preoperatively the suitability and extent of the surgical …

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Protection With High-Pressure Irrigation Of Contaminated Wounds., Robert X. Murphy Jr, Md, Ms Jul 1997

Protection With High-Pressure Irrigation Of Contaminated Wounds., Robert X. Murphy Jr, Md, Ms

Department of Surgery

No abstract provided.

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Mirizzi Syndrome Type Ii: Is Laparoscopic Cholecystectomy Justified?, D C Desai, R D Smink Jul 1997

Mirizzi Syndrome Type Ii: Is Laparoscopic Cholecystectomy Justified?, D C Desai, R D Smink

Department of Surgery Faculty Papers

Mirizzi syndrome type II is an uncommon cause of obstructive jaundice caused by an inflammatory response to an impacted gallstone in Hartmann's pouch or the cystic duct with a resultant cholecystocholedochal fistula. Two cases of Mirizzi syndrome type II are presented. Clinically only one patient had jaundice and endoscopic retrograde cholangiopancreatogram (ERCP) established a preoperative diagnosis of Mirizzi syndrome. The other patient's diagnosis of Mirizzi syndrome was made intraoperatively. It is important to properly identify the anatomy at the time of surgery to avoid compromising the common bile duct. Operative treatment of Mirizzi syndrome type II includes laparoscopic or open …

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Endothelial Nitric Oxide Synthase And Growth Factor Regulation Of Flow-Mediated Vascular Remodeling, David Anthony Tulis Jul 1997

Endothelial Nitric Oxide Synthase And Growth Factor Regulation Of Flow-Mediated Vascular Remodeling, David Anthony Tulis

Theses and Dissertations in Biomedical Sciences

This study was designed to characterize structural remodeling of male Wistar rat mesenteric arteries exposed to elevated blood flow in vivo for 1, 3, or 7 days. A series of arterial ligations induced blood flow increases in ileal and second-order branch arteries compared to same animal control vessels. Neither mean carotid nor local mesenteric arterial pressures changed significantly pre- to post-ligation. The primary flow-mediated force in both vessels was shear stress with possible involvement of acute stretch-induced wall stress in the ileal artery. Significant luminal expansion and medial wall hypertrophy occurred in the ileal and second-order arteries in a time-dependent …

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Ambulatory Arthroscopic Knee Surgery Results Of Partial Meniscectomy, Muhammad Umar Jan 1997

Ambulatory Arthroscopic Knee Surgery Results Of Partial Meniscectomy, Muhammad Umar

Section of Orthopaedic Surgery

In an open prospective study the results of arthroscopic partial meniscectomy were reviewed in 188 knees. Group I comprised of 139 (65%) knees with pure meniscus lesions without any ligament laxity, the remaining 49 (35%) knees in group II had anterior cruciate ligament (ACL) deficiency in addition to meniscus lesions. In group I, 93% had excellent to good and 7% had fair results by criteria of Tapper and Hoover. In group II, 75% had excellent to good and 25% had fair results. Arthroscopic knee surgery was a good method of identifying patients in group II who required anterior cruciate reconstruction. …

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Re: Midpalmar Approach To The Carpal Tunnel: An Alternative To Endoscopic Release., Robert X. Murphy Jr, Md, Ms Jan 1997

Re: Midpalmar Approach To The Carpal Tunnel: An Alternative To Endoscopic Release., Robert X. Murphy Jr, Md, Ms

Department of Surgery

No abstract provided.

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Axotomy And Regeneration Of The Rat Facial Nerve: A Histomorphometric Study Of The Facial Nucleus, Nerve And Orbicularis Oculi Muscle In An Experimental Model Of Facial Paralysis, Peter Konstantinos Thanos Jan 1997

Axotomy And Regeneration Of The Rat Facial Nerve: A Histomorphometric Study Of The Facial Nucleus, Nerve And Orbicularis Oculi Muscle In An Experimental Model Of Facial Paralysis, Peter Konstantinos Thanos

Theses and Dissertations in Biomedical Sciences

One of the most unsettling sequela of facial paralysis (FP) is the loss of eye sphincter function and the blink response, leading to functional, psychological and aesthetic deficits. A medley of restorative microsurgery approaches have been employed in treating these deficits, however full recovery of function remains elusive. The present research utilized the rat model of facial paralysis, and consisted of three stages. Stage I examined the facial motor neuron (FMN) pool of the eye sphincter (orbicularis oculi muscle=OOM) and identified the facial nerve branch which provides the majority of innervation to the OOM. II. Examined the efficacy of the …

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Punitive Damages...Just So You Know., Geoffrey G. Hallock Md Dec 1996

Punitive Damages...Just So You Know., Geoffrey G. Hallock Md

Department of Surgery

No abstract provided.

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Method Of Tendon Repair, Bradley B. Hill Jul 1996

Method Of Tendon Repair, Bradley B. Hill

Surgery Faculty Patents

A method for repairing a transected or torn flexor or extensor tendon of a finger that has retracted proximally within its protective sheath includes the steps of: (a) visually locating a distal end of the tendon within the sheath; (b) engaging the distal end of the tendon, (c) pulling the tendon distally through the sheath to a tendon mending position; and (d) repairing the tendon.

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Needle Localization Of Non-Palpable Breast Lesions, S Khan, N Mitha, F Kazi, M Siddiqui Jul 1996

Needle Localization Of Non-Palpable Breast Lesions, S Khan, N Mitha, F Kazi, M Siddiqui

Department of Surgery Docs

Screening mammography identifies suspicious, non palpable mammary lesions. Mammographic needle localization (MNL) is currently being used to facilitate excision biopsy of these lesions. Thirty-two patients underwent biopsies of the breast after MNL for non-palpable lesions. Mammographic indications for biopsy consisted of microcalcifications (48%), mass or abnormal density (21%) or mass+abnormal density (24%). The carcinoma was identified in four cases (12%). Two of these were in situ, one was microinvasive and one was frankly invasive. Three were treated with a modified radical mastectomy. One of these non palpable lesion demonstrated nodal metastasis but none showed distant metastasis. All radiologically detected abnormalities …

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Penile Fracture, M A. Khan, M N. Sulaiman Jun 1996

Penile Fracture, M A. Khan, M N. Sulaiman

Department of Surgery Docs

No abstract provided.

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Complications, Untoward Events, And Reality., Geoffrey G. Hallock Md May 1996

Complications, Untoward Events, And Reality., Geoffrey G. Hallock Md

Department of Surgery

The only surgeons who do not have deal with complications are those who do not operate.1

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Prefabrication Of A Secondary Tram Flap., Geoffrey G. Hallock Md May 1996

Prefabrication Of A Secondary Tram Flap., Geoffrey G. Hallock Md

Department of Surgery

A secondary TRAM flap was prefabricated in a rat model using the rectus muscle. The right rectus muscle was elevated as an inferiorly pedicled muscle flap in one experimental group (n = 6) and as a superiorly pedicled muscle flap in a second group (n = 5) and then sandwiched between a silicone sheet and the abdominal skin. Two weeks later, the abdominal skin and attached rectus muscle were elevated over the silicone sheet as a secondary TRAM flap. The surviving skin paddle areas of these prefabricated TRAM flaps were compared with superiorly (n = 7) and inferiorly (n = …

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The Extranasal Glioma - A Cause Of Neonatal Respiratory Distress, Muneer Amanullah, F Attar Z Mar 1996

The Extranasal Glioma - A Cause Of Neonatal Respiratory Distress, Muneer Amanullah, F Attar Z

Department of Surgery Docs

Normal brain tissue in an abnonnal configuration, occurring at a site away from the cranial cavity, is temied an Extranasal Glioma. Since its first description in 1852 by Reid2, only 140 patients with this entity have been reported. Heterotopic brain tissue when present in a confined area may cause obstmction, pressure and pain. Its occurrence in the nasopharyngeal region is relatively rare and only 19 cases have been reported so far2, the majority presenting with respiratory distress in the early neonatal period. The objective of this report is to create an awareness amongst the physicians of …

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Knowledge, Sources Used And Factors Considered In The Surgical Treatment Decisions Of Women With Breast Cancer, Debra J. Bisel Jan 1996

Knowledge, Sources Used And Factors Considered In The Surgical Treatment Decisions Of Women With Breast Cancer, Debra J. Bisel

Masters Theses

The purpose of this replication study was to examine how women with breast cancer reached their decision for surgical treatment (Ward, Heidrich and Wolberg 1989). Twenty-one women who met the surgical criteria, i.e. option for Breast Conserving surgery or Modified Radical Mastectomy, completed four surveys 1 to 7 days post operatively. The women were divided into two groups, 13 who had Breast Conserving surgery and 8 who had Modified Radical Mastectomy. The surveys assessed demographic characteristics of the groups, the level of knowledge regarding breast cancer, factors considered important in reaching the decision for surgery and the sources of information …

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Ventricular Remodeling Following Infant-Pediatric Cardiac Transplantation. Does Age At Transplantation Or Size Disparity Matter?, Girish S. Shirali, F Lombano, W L. Beeson, D A. Dyar, N F. Mulla, A Khan, J K. Johnston, R E. Chinnock, S R. Gundry, A J. Razzouk Dec 1995

Ventricular Remodeling Following Infant-Pediatric Cardiac Transplantation. Does Age At Transplantation Or Size Disparity Matter?, Girish S. Shirali, F Lombano, W L. Beeson, D A. Dyar, N F. Mulla, A Khan, J K. Johnston, R E. Chinnock, S R. Gundry, A J. Razzouk

Manuscripts, Articles, Book Chapters and Other Papers

Early left ventricular (LV) remodeling following pediatric cardiac transplantation has not been described. To identify patterns and determinants of change in left ventricular mass and volume posttransplant, we studied 125 consecutive children who underwent cardiac transplantation between January 1, 1989 and July 31, 1993. Two-dimensional imaging-directed M-mode echocardiograms were studied weekly until 26 weeks post-transplant. LV mass and volume (indexed to BSA1.5) were measured. LV mass index increased until 3 weeks post-transplant, and then decreased. The mean decrement in LV mass index after 8 weeks post-transplant (relative to baseline) was significantly larger in patients with donor-recipient weight ratio > 1.5 compared …

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Constitutive Alzheimer's-Type Tau Epitopes In A Neuritogenic Rat Cns Cell Line, Mary P. Lambert, Shasta Sabo, Chi Zhang, S. Ather Enam, William L. Klein Jul 1995

Constitutive Alzheimer's-Type Tau Epitopes In A Neuritogenic Rat Cns Cell Line, Mary P. Lambert, Shasta Sabo, Chi Zhang, S. Ather Enam, William L. Klein

Section of Neurosurgery

Paired helical filaments (PHFs) of Alzheimer's disease (AD) largely comprise hyperphosphorylated forms of the cytoskeletal protein tau. AD-type tau phosphoepitopes, detected by various monoclonal antibodies, are absent from normal adult neurons, but recent studies have shown that their expression may contribute to neuritogenesis and axon differentiation in the developing nervous system. Therefore, we have examined a brain nerve cell line that is spontaneously neuritogenic for possible expression of AD-type tau epitopes. The neuritogenic rat brain cell line B103 was found to constitutively produce two AD-related epitopes of tau, detected by cellular immunofluorescence studies with the PHF-1 and Alz-50 monoclonal antibodies. …

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The Rat Tram Flap: A Human Analogue?, Geoffrey G. Hallock Md Jul 1995

The Rat Tram Flap: A Human Analogue?, Geoffrey G. Hallock Md

Department of Surgery

No abstract provided.

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Cosmetic Trauma Surgery., Geoffrey G. Hallock Md Feb 1995

Cosmetic Trauma Surgery., Geoffrey G. Hallock Md

Department of Surgery

No abstract provided.

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Loss Of The Tumor Suppressor Genes P53 And Brca1 In Prophylactic Mastectomy Cancer Patients, Garrett Griffith Losh Jan 1995

Loss Of The Tumor Suppressor Genes P53 And Brca1 In Prophylactic Mastectomy Cancer Patients, Garrett Griffith Losh

Presidential Scholars Theses (1990 – 2006)

More importantly, this study has shown that prophylactic mastectomy surgery is a viable and worthwhile treatment to prevent breast cancer recurrence. It is hoped that this information will increase the knowledge of breast cancer. For the same reason, this paper has attempted to explain what cancer is while describing how the genetics of a person cause or contribute to its development. Most of all, it is hoped that this paper will emphasize the severity of this disease in the United States today and tomorrow .

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Ureterorenoscopy In Children, K Rasheed, A Memon Aug 1994

Ureterorenoscopy In Children, K Rasheed, A Memon

Section of Paediatric Surgery

No abstract provided.

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Intestinal Obstruction In Adults At The Aga Khan University Hospital, S Q. Hasnain, M Ahmed Jun 1994

Intestinal Obstruction In Adults At The Aga Khan University Hospital, S Q. Hasnain, M Ahmed

Department of Surgery Docs

During the period January, 1987 to June, 1991, 208 adults with mechanical bowel obstruction were managed at The Aga Khan University Hospital (AKUH). Post-operative adhesions accounted for 34% of the cases and were the most frequent cause of intestinal obstruction. External hemia (16%), malignancy (13.5%) and tuberculous stricture (10%) were the next most frequent causes. The predominance of adhesive intestinal obstruction at AKUH shows a trend towards a Western disease pattern. Socioeconomic status was a significant determinant of the cause of obstruction. The proportion of self paying to welfare patients was significantly lower in tuberculous obstruction as compared with adhesive …

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Conjoined Twins - A Review Of Literature With Two Case Studies, Naaeem Uz-Zafar Khan, Nadeem Ullah Khan, Khalid Matin, Adnan Zaidi Mar 1994

Conjoined Twins - A Review Of Literature With Two Case Studies, Naaeem Uz-Zafar Khan, Nadeem Ullah Khan, Khalid Matin, Adnan Zaidi

Department of Emergency Medicine

Two cases of conjoined twins have been reported. A review of literature is given.

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Clients' Perceptions Of Preparedness For Discharge Home Following Total Hip Or Knee Replacement Surgery, Cindy H. Nicholson Jan 1994

Clients' Perceptions Of Preparedness For Discharge Home Following Total Hip Or Knee Replacement Surgery, Cindy H. Nicholson

Masters Theses

This study used a descriptive design to evaluate discharge planning by examining the clients' perception of preparedness for discharge home following total hip or knee replacement surgery. The conceptual framework was based upon the Betty Neuman Systems Model.; This study used Lawton's (1991) "Discharge Preparation Questionairre" to ascertain the clients' perceptions of preparedness in 10 discharge categories. Perceived preparation was measured using a 5 point summated rating scale. The study site was a 42-bed orthopedic unit in a 119 bed acute care hospital in Southeast Michigan. The convenience sample, of 46 adult clients, were interviewed by phone 3 days following …

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A Comparison Of Four Muscle Relaxant Techniques And Their Incidence Of Postoperative Myalgia In Ambulatory Patients, William James Garske Jr. Dec 1993

A Comparison Of Four Muscle Relaxant Techniques And Their Incidence Of Postoperative Myalgia In Ambulatory Patients, William James Garske Jr.

Community & Environmental Health Theses & Dissertations

Postoperative myalgia was measured 24 and 72 hours following the administration of four different anesthetic regimens to 36 patients undergoing outpatient or 23-hour admission procedures. Each patient, ASA class I or II, was to undergo procedures of limited duration, 30 to 90 minutes, and surgical stimulation, including procedures such as knee arthroscopy, hernia repair, and breast biopsy. Anesthesia was induced with propofol 1.5 mg/kg, fentanyl 50 mcg, and maintained with O2 , N2O, and isoflurane. Group I (n=20), the control, received no muscle relaxant and was maintained with mask ventilation. Group II (n=5) received succinylcholine 1.5 mg/kg …

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A Simple Technique Of Umbilical Port Closure In Laparoscopic Cholecystectomy, A Khan, M N. Siddiqui, M Ahmed Nov 1993

A Simple Technique Of Umbilical Port Closure In Laparoscopic Cholecystectomy, A Khan, M N. Siddiqui, M Ahmed

Department of Surgery Docs

No abstract provided.

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Retained Stones In The Common Bile Duct: Results Of Management, Kamran Hamid, R Azami, W Jaffery, T Hameed May 1993

Retained Stones In The Common Bile Duct: Results Of Management, Kamran Hamid, R Azami, W Jaffery, T Hameed

Department of Surgery Docs

Seventeen patients underwent treatment for retained common bile duct stones. In 7 patients the stones were removed via a T-tube tract using steerable catheters while 5 patients underwent ERCP and sphincterotomy and 5 underwent surgical re-exploration. Considering morbidity, mortality, success rate and patients' stay in the hospital, non-operative modalities should be the treatment of choice for retained common bile duct stones.

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Harpoon Extraction Of A Common Bile Duct Stone Impacted At The Ampulla Of Vater With Needle-Knife Sphincterotome., Vivian Mcalister, Andre Roy, Ron Passi Jan 1993

Harpoon Extraction Of A Common Bile Duct Stone Impacted At The Ampulla Of Vater With Needle-Knife Sphincterotome., Vivian Mcalister, Andre Roy, Ron Passi

Data and Test Instruments

The urgency of dealing with impacted ampullary stones is underlined in the first case reported by Opie6 at the autopsy of a young woman. Impacted ampullary stones that prevent papillary cannulation and standard sphincterotomy make up less than 5% of common bile duct stones seen at ERCP.3 Several series suggest the safe use of needle-knife sphincterotomy to create a choledochoduodenal fistula or to allow subsequent standard sphincterotomy in this situation. These series have also reported failure to extract the stone so that surgical removal was required.3,4Successful sphincterotomy may facilitate the early diagnosis of tumors that cause the ampulla to bulge. …

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Penile Constrictive Band Injury, Zafar Nazir, Khalid Rasheed, Farhat Moazam Jan 1993

Penile Constrictive Band Injury, Zafar Nazir, Khalid Rasheed, Farhat Moazam

Section of Paediatric Surgery

Penile strangulation caused by a thread or human hair is an uncommon cause of urethral injury described in paediatric piactice. Five children presented with this entity to the Aga Khan University Hospital, Karachi between August, 1991 and August, 1992. Three children had uneventful recoveries after removal of the contricting agent. Two patients developed urethrocutaneaus fistulae and partial amputation of the penis because of late presentation Early recognition and removal of the constricting agent is necessary to prevent serious complications

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