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Articles 2461 - 2490 of 5939

Full-Text Articles in Surgery

Locked In: The Impact Of The Pandemic On Suicide, Evelyn Coile, Tatiana Eversley-Kelso, Eric Shaw, Sara Hamilton Jan 2022

Locked In: The Impact Of The Pandemic On Suicide, Evelyn Coile, Tatiana Eversley-Kelso, Eric Shaw, Sara Hamilton

South Atlantic Division GME Research Day 2022

No abstract provided.


Changes In Patterns And Outcomes Of Trauma Patients After Betterment In Law And Order Situation Of The City, Sabah Uddin Saqib, Hasnain Zafar Jan 2022

Changes In Patterns And Outcomes Of Trauma Patients After Betterment In Law And Order Situation Of The City, Sabah Uddin Saqib, Hasnain Zafar

Section of General Surgery

Objective: To assess the impact of the law and order situation of a city on the pattern of traumatic injuries and the overall outcomes of trauma victims.
Methods: The retrospective study of prospective trauma surgery data was done at Aga Khan University Hospital, Karachi, and comprised data of patients with torso injuries before the improvement of law and order situation from January 2012 to March 2013 in Group A, and of those with similar injuries after the law and order situation improved in the city from January 2018 to March 2019 in Group B. The required data was collected by …


Traumatic Morel-Lavallee Injury To The Abdomen After A Seatbelt Injury; A Rarely Documented Case With An Uncommon Subdermal Matrix Reconstruction, Austin Mccrea, Saptarshi Biswas Jan 2022

Traumatic Morel-Lavallee Injury To The Abdomen After A Seatbelt Injury; A Rarely Documented Case With An Uncommon Subdermal Matrix Reconstruction, Austin Mccrea, Saptarshi Biswas

South Atlantic Division GME Research Day 2022

No abstract provided.


Changes In Injury Patterns Associated With Elevated Blood Alcohol Level, Isabella Moncada, Heather Rhodes, Nasser Mohammad, Nicole Pascarella, Christina Catlla, Saptarshi Biswas Jan 2022

Changes In Injury Patterns Associated With Elevated Blood Alcohol Level, Isabella Moncada, Heather Rhodes, Nasser Mohammad, Nicole Pascarella, Christina Catlla, Saptarshi Biswas

South Atlantic Division GME Research Day 2022

No abstract provided.


Traumatic Dissection Of The Internal Carotid Artery After Blunt Cervical Trauma And Discussio Of Management Of The Same, Austin Mccrea, Valentino Piacentino, Saptarshi Biswas Jan 2022

Traumatic Dissection Of The Internal Carotid Artery After Blunt Cervical Trauma And Discussio Of Management Of The Same, Austin Mccrea, Valentino Piacentino, Saptarshi Biswas

South Atlantic Division GME Research Day 2022

No abstract provided.


Optimal Timing And Outcomes Among Covid-19 Patients Undergoing Tracheostomy, Steven K M Vuu, Huazhi Liu, Jennifer Demuro, Laura Mena Albors, Tandis Soltani, Ettore Crimi, Darwin Ang Jan 2022

Optimal Timing And Outcomes Among Covid-19 Patients Undergoing Tracheostomy, Steven K M Vuu, Huazhi Liu, Jennifer Demuro, Laura Mena Albors, Tandis Soltani, Ettore Crimi, Darwin Ang

North Florida Division GME Research Day 2022

No abstract available.


Splenectomy In A Patient With Von Willebrand Disease And Itp. Hemostatic Challenges, Perioperative Resuscitation, Resource Allocation And Challenges Of Management In A Regional L1 Center, Taylor Locklear, Akash Patel, Saptarshi Biswas Jan 2022

Splenectomy In A Patient With Von Willebrand Disease And Itp. Hemostatic Challenges, Perioperative Resuscitation, Resource Allocation And Challenges Of Management In A Regional L1 Center, Taylor Locklear, Akash Patel, Saptarshi Biswas

South Atlantic Division GME Research Day 2022

No abstract provided.


Validation Of The European Hernia Society Ventral Hernia Classification System, Jose Lopez-Vera, Erik Askenasy, Jacob Greenberg, Jerrod Keith, Robert Martindale, J Scott Roth, Zuhair Ali, Mike K. Liang Jan 2022

Validation Of The European Hernia Society Ventral Hernia Classification System, Jose Lopez-Vera, Erik Askenasy, Jacob Greenberg, Jerrod Keith, Robert Martindale, J Scott Roth, Zuhair Ali, Mike K. Liang

Gulf Coast Division GME Research Day 2022

No abstract provided.


Rib Plating Hardware Failure And Surgical Revision, Valerie Vazquez, Laura Mena-Albors, Matthew Holman, Joshua Hagan, Olga Zayko Jan 2022

Rib Plating Hardware Failure And Surgical Revision, Valerie Vazquez, Laura Mena-Albors, Matthew Holman, Joshua Hagan, Olga Zayko

North Florida Division GME Research Day 2022

No abstract available.


Anesthesia With Mitochondrial Disease, Ethan Mosley, Cameron Killmer, Saptarshi Biswas Jan 2022

Anesthesia With Mitochondrial Disease, Ethan Mosley, Cameron Killmer, Saptarshi Biswas

South Atlantic Division GME Research Day 2022

No abstract provided.


Extensive Intra-Abdominal Adhesions In A Patient With No Previous Abdominal Surgeries, Jared Jackson, Saptarshi Biswas Jan 2022

Extensive Intra-Abdominal Adhesions In A Patient With No Previous Abdominal Surgeries, Jared Jackson, Saptarshi Biswas

South Atlantic Division GME Research Day 2022

No abstract provided.


Gibbon Surgical Society Email Newsletter - Get To Know Gibbon, Gibbon Surgical Society Jan 2022

Gibbon Surgical Society Email Newsletter - Get To Know Gibbon, Gibbon Surgical Society

Gibbon Surgical Society Newsletter

No abstract provided.


Novel Repair Of Costal Margin Rupture With Preoperative 3d Planning, Casey T. Walk, Gregory Semon Jan 2022

Novel Repair Of Costal Margin Rupture With Preoperative 3d Planning, Casey T. Walk, Gregory Semon

Department of Surgery Faculty Publications

WHAT WOULD YOU DO? This is a 32-year-old man involved in a motor vehicle crash in 2019 with chronic left-sided rib pain since. He was initially treated with physical therapy and medical management with no improvement. CT imaging in 2021 noted displaced left lateral seventh and eighth ribs, noted chest wall deformity, and when three-dimensional (3D) reconstruction of his ribs was created, this noted a left- sided costal margin rupture at the sixth and seventh ribs.


Variability And Outcomes Of Medical And Lifestyle Management Of Peripheral Arterial Disease At The Time Of Lower Extremity Bypass, Ryan Howard, Jeremy Albright, Matthew Corriere, Nicholas Osborne, Eugene Laveroni, Peter Henke Jan 2022

Variability And Outcomes Of Medical And Lifestyle Management Of Peripheral Arterial Disease At The Time Of Lower Extremity Bypass, Ryan Howard, Jeremy Albright, Matthew Corriere, Nicholas Osborne, Eugene Laveroni, Peter Henke

Conference Presentation Abstracts

Background: First-line treatment of peripheral arterial disease (PAD) involves medical therapy and lifestyle modification. Specifically, the 2016 American Heart Association/American College of Cardiology guidelines for the management of PAD make Class I recommendations for antiplatelet therapy, statin therapy, antihypertensive therapy, and cilostazol therapy, as well as exercise therapy and smoking cessation. Although evidence supports medical and lifestyle management of PAD before surgical intervention, it is currently unclear whether clinical practice reflects this. Moreover, it is also unknown whether variability in medical and lifestyle optimization before revascularization affects short- and long-term outcomes. This study was conducted to determine the proportion of …


Loss Of Smad4 Is Associated With Poor Tumor Immunogenicity And Reduced Pd-L1 Expression In Pancreatic Cancer, Daniel R. Principe, Patrick W. Underwood, Sandeep Kumar, Kaytlin E. Timbers, Regina M. Koch, Jose G. Trevino, Hidayatullah G. Munshi, Ajay Rana Jan 2022

Loss Of Smad4 Is Associated With Poor Tumor Immunogenicity And Reduced Pd-L1 Expression In Pancreatic Cancer, Daniel R. Principe, Patrick W. Underwood, Sandeep Kumar, Kaytlin E. Timbers, Regina M. Koch, Jose G. Trevino, Hidayatullah G. Munshi, Ajay Rana

Surgery Publications

Transforming Growth Factor β (TGFβ) is a key mediator of immune evasion in pancreatic ductal adenocarcinoma (PDAC), and the addition of TGFβ inhibitors in select immunotherapy regimens shows early promise. Though the TGFβ target SMAD4 is deleted in approximately 55% of PDAC tumors, the effects of SMAD4 loss on tumor immunity have yet to be fully explored. Using a combination of genomic databases and PDAC specimens, we found that tumors with loss of SMAD4 have a comparatively poor T-cell infiltrate. SMAD4 loss was also associated with a reduction in several chemokines with known roles in T-cell recruitment, which was recapitulated …


Role Of Micrornas In Non-Functioning Pituitary Adenoma, Mehak Ismail Rajani, Yumna Mirza, Rohan Advani, Syed Muhammad Adnan Ali, Ather Enam Jan 2022

Role Of Micrornas In Non-Functioning Pituitary Adenoma, Mehak Ismail Rajani, Yumna Mirza, Rohan Advani, Syed Muhammad Adnan Ali, Ather Enam

Centre for Innovation in Medical Education

Non-functioning pituitary adenomas account for 30% of anterior pituitary tumours. Based on their inability to secrete hormones, these are often diagnosed incidentally or due to pressure symptoms. Understanding the pathogenesis of these adenomas can provide insight into factors leading to its progression and serving as biomarkers for early recognition. A literature search was performed in the current narrative review for articles published in PubMed for the last 10 years till January 2020 on micro-ribonucleic acid involved in the pathogenesis of non-functioning pituitary adenomas. Of the 478 articles found, 21(4.4%) were filtered. In total, 106 micro-ribonucleic acids were identified, 25(23.5%) of …


Hernia Prevention Utilizing Mesh And/Or Small Bites: A 2x2 Factorial Randomized Controlled Trial, Rainna Coelho, Naila Dhanani, Erik Askenasy, Stefanos Millas, Karla Bernardi, Zuhair Ali, Lillian S. Kao, Mike Liang Jan 2022

Hernia Prevention Utilizing Mesh And/Or Small Bites: A 2x2 Factorial Randomized Controlled Trial, Rainna Coelho, Naila Dhanani, Erik Askenasy, Stefanos Millas, Karla Bernardi, Zuhair Ali, Lillian S. Kao, Mike Liang

Gulf Coast Division GME Research Day 2022

No abstract provided.


Undertriage Of Elderly Trauma Patients With Comorbid Conditions, Taylor Locklear, Heather Rhodes, Nasser Mohammad, Nicole Pascarella, Rudy Flores, Antonio Pepe Jan 2022

Undertriage Of Elderly Trauma Patients With Comorbid Conditions, Taylor Locklear, Heather Rhodes, Nasser Mohammad, Nicole Pascarella, Rudy Flores, Antonio Pepe

South Atlantic Division GME Research Day 2022

No abstract provided.


Primary Retroperitoneal Mucinous Tumor – A Cyst That Is Not So Simple, Scott Cruise, Aaron Dan Pinnola, Abhishek Srivastava Jan 2022

Primary Retroperitoneal Mucinous Tumor – A Cyst That Is Not So Simple, Scott Cruise, Aaron Dan Pinnola, Abhishek Srivastava

South Atlantic Division GME Research Day 2022

No abstract provided.


Isolated Hip Fractures: Factors Beyond 48 Hours, Evelyn Coile, Heather Rhodes, Nassar Mohammad, Nicole Pascarella, Tatiana Eversley Kelso, Christa Zino, Summer Rabon, Saptarshi Biswas, James Dunne, Antonio Pepe Jan 2022

Isolated Hip Fractures: Factors Beyond 48 Hours, Evelyn Coile, Heather Rhodes, Nassar Mohammad, Nicole Pascarella, Tatiana Eversley Kelso, Christa Zino, Summer Rabon, Saptarshi Biswas, James Dunne, Antonio Pepe

South Atlantic Division GME Research Day 2022

No abstract provided.


Congenital Non-Union Of C1 Leading To Quadriplegia Following A Roller Coaster Ride, Kelly Champlin, Saptarshi Biswas Jan 2022

Congenital Non-Union Of C1 Leading To Quadriplegia Following A Roller Coaster Ride, Kelly Champlin, Saptarshi Biswas

South Atlantic Division GME Research Day 2022

No abstract provided.


Bilateral Renal Infarcts From Blunt Trauma In A Healthy Young Female Patient. Clinical Dilemmas, Diagnostic Conundrum And Management., Kelly Champlin, Austin Mccrea, Saptarshi Biswas Jan 2022

Bilateral Renal Infarcts From Blunt Trauma In A Healthy Young Female Patient. Clinical Dilemmas, Diagnostic Conundrum And Management., Kelly Champlin, Austin Mccrea, Saptarshi Biswas

South Atlantic Division GME Research Day 2022

No abstract provided.


Radiation Of Meningioma Dural Tail May Not Improve Tumor Control Rates., Keenan Piper, Siyuan Yu, Mohammad Taghvaei, Christian Fernandez, Nikolaos Mouchtouris, Rupert D Smit, Clifford Yudkoff, Sarah Collopy, Maikerly Reyes, Pascal Lavergne, Michael Karsy, Giyarpuram Prashant, Wenyin Shi, James J. Evans Jan 2022

Radiation Of Meningioma Dural Tail May Not Improve Tumor Control Rates., Keenan Piper, Siyuan Yu, Mohammad Taghvaei, Christian Fernandez, Nikolaos Mouchtouris, Rupert D Smit, Clifford Yudkoff, Sarah Collopy, Maikerly Reyes, Pascal Lavergne, Michael Karsy, Giyarpuram Prashant, Wenyin Shi, James J. Evans

Student Papers, Posters & Projects

Introduction: Dural tails are thickened contrast-enhancing portions of dura associated with some meningiomas. Prior studies have demonstrated the presence of tumor cells within the dural tail, however their inclusion in radiation treatment fields remains controversial. We evaluated the role of including the dural tail when treating a meningioma with stereotactic radiation and the impact on tumor recurrence.

Methods: This is a retrospective, single-institution, cohort study of patients with intracranial World Health Organization (WHO) grade 1 meningioma and identified dural tail who were treated with stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy (FSRT) from January 2012 to December 2018. SRS and …


Eagle Syndrome: Efficacies Of Medical And Surgical Treatments, Kirklin Mitchell Jan 2022

Eagle Syndrome: Efficacies Of Medical And Surgical Treatments, Kirklin Mitchell

Capstone Showcase

Eagle Syndrome is a rare syndrome caused by elongation of the styloid process of the temporal bone or calcification of the stylohyoid ligament occurring in a very small percentage of the population that can cause a wide range of common symptoms, leading to it being often misdiagnosed. While there are no set standards for treating Eagle Syndrome, both pharmaceutical and surgical options exist. Pharmaceutical options are often ineffective in long term treatment so surgery is usually required for full symptom resolution. Transoral and Transcervical surgeries have similar efficacies but each come with important drawbacks when considering which type of surgery …


Percutaneous Coronary Intervention Using Second Generation Drug-Eluting Stents Vs Coronary Artery Bypass Graft In Left Main Coronary Artery And Multivessel Coronary Artery Disease, Eric Kim Jan 2022

Percutaneous Coronary Intervention Using Second Generation Drug-Eluting Stents Vs Coronary Artery Bypass Graft In Left Main Coronary Artery And Multivessel Coronary Artery Disease, Eric Kim

Capstone Showcase

Many of the studies that are used in reference to the clinical decision making between PCI vs CABG use BMS or first-generation DES as a comparison. With the advancement of stent technology, second-generation DES have emerged with improved efficacy and overall outcome rates compared to BMS and first-generation DES. Some of the newer studies such as EXCEL1-2 , demonstrated noninferiority of second-generation DES to CABG but there are limited studies that support this conclusion. Currently, the studies remain divided in the impact of newer-generation PCIs, and 10-year follow up studies may be required to further validate noninferiority before it can …


Single-Incision Laparoscopic Splenectomy In Children With Massive Splenomegaly: A Prospective, Monocentric Pilot Study, Congjun Wang, Cheng Su, Chao Chen, Xianming Tang, Hong Wang, Wei Li, Yanqiang Li, Qiang Liu, Peng Chen, Yong Li, Yige Luo Jan 2022

Single-Incision Laparoscopic Splenectomy In Children With Massive Splenomegaly: A Prospective, Monocentric Pilot Study, Congjun Wang, Cheng Su, Chao Chen, Xianming Tang, Hong Wang, Wei Li, Yanqiang Li, Qiang Liu, Peng Chen, Yong Li, Yige Luo

Faculty, Staff and Student Publications

BACKGROUND: Single-incision laparoscopic splenectomy (SILS) remains a challenging procedure because of the technical difficulty. In this prospective study, we aimed to evaluate the efficacy and safety of SILS in children with massive splenomegaly.

METHODS: Pediatric patients with massive splenomegaly were recruited for SILS in a university-affiliated hospital. The data on patient demographics, clinical features, operative variables, and perioperative outcomes were collected prospectively and analyzed. According to the different surgical instruments, the patients were randomly assigned into two groups: the SILS with straight surgical instrument (SILS-S) group and the SILS with curved surgical instrument (SILS-C) group. A two-group comparative analysis was …


Cross-Mentorship: A Unique Lens Into The Realities And Challenges Of Diversity In Surgery., Marina Affi Koprowski, Karen J Dickinson, Crystal N Johnson-Mann, Martha Godfrey, Emilia J Diego, Marie Crandall, Kevin Y. Pei Md, Mhsed Jan 2022

Cross-Mentorship: A Unique Lens Into The Realities And Challenges Of Diversity In Surgery., Marina Affi Koprowski, Karen J Dickinson, Crystal N Johnson-Mann, Martha Godfrey, Emilia J Diego, Marie Crandall, Kevin Y. Pei Md, Mhsed

Other Specialties

Mentorship in surgery is a perennial topic of interest, as successful mentoring relationships are associated with improved career satisfaction, academic promotion, research productivity, and overall well-being. While it is true that certain minority groups in surgery find great personal and professional benefit in receiving and providing mentorship among “their own” (ie, a female academic surgeon mentoring a female resident), it is important to recognize that many mentoring relationships, whether intentionally or otherwise, extend across gender, sexuality, generations, race, ethnicity, and other differences. Lived examples of these include an Asian man hailing from the Northeast with no children mentoring a White …


Bibliometric Study On The Literature Related To Dental Research And Education Published In Journal Of Pakistan Medical Association, Samira Adnan, Kamil Zafar, Farhan Raza Khan, Rizwan Ullah Jan 2022

Bibliometric Study On The Literature Related To Dental Research And Education Published In Journal Of Pakistan Medical Association, Samira Adnan, Kamil Zafar, Farhan Raza Khan, Rizwan Ullah

Section of Dental-Oral Maxillofacial Surgery

Objective: To analyse characteristics of literature related to dental research and education published in a single medical journal, The Journal of Pakistan Medical Association.
Method: The bibliometric study was conducted at the Sindh Institute of Oral Health Sciences, Jinnah Sindh Medical University from March till May 2020, and comprised electronic and hand search of scientific literature relevant to dentistry published in the Journal of Pakistan Medical Association from the first issue published in 1953 till March 2020. The selected articles were analysed for year of publication, field of study, type of article, institute and country of first author, number of …


Comparison Of Surface Defects In Protaper Next And Hyflex Edm Files After Single Clinical Use: A Stereoscopic Evaluation, Faizan Javed, Momina Anis Motiwala, Farhan Raza Khan, Rabia Ghafoor Jan 2022

Comparison Of Surface Defects In Protaper Next And Hyflex Edm Files After Single Clinical Use: A Stereoscopic Evaluation, Faizan Javed, Momina Anis Motiwala, Farhan Raza Khan, Rabia Ghafoor

Section of Dental-Oral Maxillofacial Surgery

Objective: To compare the surface defects created on the ProTaper Next files versus HyFlex Electrical Discharge Machining files after single clinical use in molars.
Methods: The cross-sectional study was conducted in the dental department of the Aga Khan University Hospital, Karachi, from December 2018 to June 2019, and comprised Nickel-Titanium files belonging to HyFlex Electrical Discharge Machining and ProTaper Next to perform complete root canal treatment of molar teeth. The files were first visually examined and then analysed under 25.6x magnification using a stereomicroscope for the evaluation of surface defects. A photographic record was maintained and studied. Data was analysed …


Kidney Disease After Heart And Lung Transplantation, Carlos M Zapata, Hassan N Ibrahim Jan 2022

Kidney Disease After Heart And Lung Transplantation, Carlos M Zapata, Hassan N Ibrahim

Faculty, Staff and Student Publications

Chronic kidney disease (CKD) is not only common after lung and heart transplantation but also is associated with increased morbidity and mortality due to multiple pre-, peri- and post-transplant factors. While the exact incidence of CKD in this population is not well-defined, it seems to have gradually increased over the years as older recipients are more frequently considered. The increasing success of the procedure and expanding transplant candidate pool has allowed many with comorbid conditions to receive a transplant, which was considered prohibitive in the past. This review presents risk factors that have been linked to CKD as well as …