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Articles 45031 - 45034 of 45034

Full-Text Articles in Medical Sciences

Intracranial Aneurysm: A Dangerous Brain Lesion, G. Austin, W. Schievink, R. Gaskell, S. Richardson, E. Hanford Dec 999

Intracranial Aneurysm: A Dangerous Brain Lesion, G. Austin, W. Schievink, R. Gaskell, S. Richardson, E. Hanford

The Dr. George M. Austin Neurology Research Collection

Intracranial Aneurysm: A Dangerous Brain Lesion. G. Austin, W. Schievink, R. Gaskell, S. Richardson and E. Hanford, no date, 8 pages, possibly a poster presentation.


[Aneurysm Research At The Aneurysm Research Laboratory, Stroke Research Foundation, Inc.], George M. Austin Dec 999

[Aneurysm Research At The Aneurysm Research Laboratory, Stroke Research Foundation, Inc.], George M. Austin

The Dr. George M. Austin Neurology Research Collection

Aneurysm. George M. Austin. 1 pg.

This document provides a brief explanation of the research conducted at the Aneurysm Research Laboratory, a division of the Stroke Research Foundation, Inc., in Santa Barbara, California.


Flow Dynamics In Model Aneurysms Associated With Simulated Vasospasm, Takuo Hashimoto, George M. Austin Dec 999

Flow Dynamics In Model Aneurysms Associated With Simulated Vasospasm, Takuo Hashimoto, George M. Austin

The Dr. George M. Austin Neurology Research Collection

Flow Dynamics in Model Aneurysms Associated with Simulated Vasospasm. Takuo Hashimoto, M.D., George M. Austin, M.D. N.D., 23 pg.


Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses, Catherine M. Crosby, William E. Matchett, Stephanie S. Anguiano-Zarate, Christopher A. Parks, Eric A. Weaver, Larry R. Pease, Richard J. Webby, Michael A. Barry Dec 200

Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses, Catherine M. Crosby, William E. Matchett, Stephanie S. Anguiano-Zarate, Christopher A. Parks, Eric A. Weaver, Larry R. Pease, Richard J. Webby, Michael A. Barry

Nebraska Center for Virology: Faculty Publications

Head-to-head comparisons of conventional influenza vaccines with adenovirus (Ad) gene-based vaccines demonstrated that these viral vectors can mediate more potent protection against influenza virus infection in animal models. In most cases, Ad vaccines are engineered to be replication-defective (RD-Ad) vectors. In contrast, replication-competent Ad (RC-Ad) vaccines are markedly more potent but risk causing adenovirus diseases in vaccine recipients and health care workers. To harness antigen gene replication but avoid production of infectious virions, we developed “single-cycle” adenovirus (SC-Ad) vectors. Previous work demonstrated that SC-Ads amplify transgene expression 100-fold and produce markedly stronger and more persistent immune responses than RD-Ad vectors …