Periodontics and Periodontology Commons^™

The Role Of Cd5 In The Periodontal Disease: Insights Into Chronic Inflammation, Ellie Bybee

Annual Research Symposium

No abstract provided.

Evaluation Of Salivary Biomarkers For The Early Diagnosis Of Periodontitis And Its Association With Hypertension, Elizabeth Uoo

Annual Research Symposium

No abstract provided.

N Y State Dent J March 2022

The New York State Dental Journal

In the March 2022 issue, the reader will find the following feature articles:

• Orthognathic Surgery and Quality-of-Life Outcomes: Findings from a Hospital-Based Patient Satisfaction Survey
• Recommendations for Co-Prescription of Opioids and Naloxone in the Dental Office
• Papillon-LeFevre Syndrome: A Case Study of Two Siblings
• Treatment of Peri-implant Soft-tissue Deficiency around a Narrow Diameter Implant with Subepithelial Connective-tissue Graft: A Case Report
• Simple Lipoma Mimicking Oral Infiltrating Lipoma: Case Report

This issue includes regular columns with regional news impacting the New York membership including: editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Use Of The Deep Learning Approach To Measure Alveolar Bone Level, Chun-Teh Lee, Tanjida Kabir, Jiman Nelson, Sally Sheng, Hsiu-Wan Meng, Thomas E Van Dyke, Muhammad F Walji, Xiaoqian Jiang, Shayan Shams

Faculty, Staff and Student Publications

AIM: The goal was to use a deep convolutional neural network to measure the radiographic alveolar bone level to aid periodontal diagnosis.

MATERIALS AND METHODS: A deep learning (DL) model was developed by integrating three segmentation networks (bone area, tooth, cemento-enamel junction) and image analysis to measure the radiographic bone level and assign radiographic bone loss (RBL) stages. The percentage of RBL was calculated to determine the stage of RBL for each tooth. A provisional periodontal diagnosis was assigned using the 2018 periodontitis classification. RBL percentage, staging, and presumptive diagnosis were compared with the measurements and diagnoses made by the …

Open Your Eyes To 3d Imaging, Lea Al Matny Dds, Ms

The Journal of the Michigan Dental Association

This cover feature illuminates the transformative role of cone beam computed tomography (CBCT) in dental diagnostics and treatment planning. As CBCT evolves from specialized to commonplace usage, its impact on various dental specialties, including oral surgery, periodontics, orthodontics, and general dentistry, becomes apparent. The article underscores the necessity of understanding CBCT's fundamental concepts and emphasizes the importance of customized imaging protocols tailored to patients' needs. Comprehensive evaluation of CBCT scans reveals anatomical variations, aids in detecting periapical pathosis, visualizing root fractures, assessing external cervical root resorption, and contributes to airway analysis. Moreover, the article explores CBCT's expanding role beyond implant …

Treatment Of Peri-Implant Soft Tissue Deficiency Around A Narrow Diameter Implant With Subepithelial Connective Tissue Graft: A Case Report, Jaewon Kim Dds, Ms, Phd, Abhiram Maddi Dds Msc Phd

The New York State Dental Journal

Narrow diameter implants and mini-implants are preferred by dentists for restoration of missing teeth on narrow ridges. However, such implants are associated with long-term complications including soft tissue deficiencies. This case report describes a novel approach using a connective tissue graft to resolve peri-implant mucositis. A 66-year old male patient presented with inflammation and abscess in relation to a mini-implant, at the upper left incisor, on the facial aspect. Deficiencies of keratinized tissue and width of attached gingiva were observed. Surgical management was performed using subepithelial connective tissue. An 18-month follow up showed increased width of attached gingiva at the …

Papillon-Lefevre Syndrome: A Case Study Of Two Siblings, Babak Bina Dmd, Boris Zats Dds, Tom Rubinstein Dmd

The New York State Dental Journal

Papillon-LeFevre Syndrome (PLS) is a rare autosomal recessive disease, associated with palmar-plantar hyperkeratosis and premature loss of both deciduous and permanent teeth. Treatment of this disease continues to be a challenge to the medical and dental professions. The following is a case report of two siblings of Chinese origin, diagnosed with Papillon-LeFevre syndrome and follows them for 10 subsequent years.

The Effect Of Er:Yag, Nd:Yag And Co2 Laser Combined With Hydrogen Peroxide, Sodium Hypochlorite, Chlorohexidine Or Fluoride On Reducing Oral Bacterial Count Implicated In Root Caries, Nitya Reddy

Theses and Dissertations

Purpose: Lasers have been used for treatment of dentinal hypersensitivity and for various bacterial reduction indications in periodontology. Their effectiveness in killing oral bacteria is not well known. The compounding effect of the combination of a laser treatment and adjunct antimicrobial agent use on bacterial viability is still evolving. The purpose of this in vitro study was to evaluate the effect of three lasers commonly used in dentistry in conjunction with chlorhexidine (CHX), hydrogen peroxide (H₂O₂), sodium hypochlorite (NaOCl), or sodium fluoride (NaF) on viability of oral bacteria associated with root caries.

Methods: Three …

The Frequency Of Periodontitis In End‑Stage Renal Disease On Hemodialysis In A Sample Of Egyptian Population: Multi‑Center Clinical Cross‑Sectional Study, Enji Ahmed Mahmoud, Asmaa Abobakr, Eman Khalil, Radwa Raghib

Dentistry

Background: There is a general assumption that periodontal disease is highly prevalent among patients with chronic renal failure undergoing hemodialysis. The aim of the study to estimate the frequency of periodontitis in patients on hemodialysis among a sample of the Egyptian population, as well as the correlation between different clinical parameters of periodontal status with serum creatinine and blood urea. This may rule out the bidirectional relationship between periodontitis and renal failure in patients on hemodialysis. Methods: The study was conducted on 263 hemodialysis patients (165 males and 98 females) at three dialysis centers in Benha Governorate, Egypt (Benha Hospital, …

10-Minute Ebd: Factors Impacting Gingival Margin Position Following Esthetic Crown Lengthening, I-Ting (David) Lee

The Journal of the Michigan Dental Association

The esthetic crown lengthening procedure aims to address gingival concerns and achieve harmonious crown proportions. This article explores factors influencing gingival margin position post-surgical intervention, focusing on patients with excessive gingival display. The PICO question investigates gingival changes six months post-surgery. A comprehensive literature search using keywords such as "esthetic crown lengthening" and "gummy smile" identifies relevant articles. Results indicate varied outcomes, emphasizing the importance of individualized approaches. Notably, factors like flap margin suture placement impact tissue rebound. This study underscores the complexity of esthetic crown lengthening, emphasizing the need for tailored strategies to ensure optimal outcomes.

Dental Pulp Stem Cell Heterogeneity: Finding Superior Quality “Needles” In A Dental Pulpal “Haystack” For Regenerative Medicine-Based Applications, Zi Y. Kok, Nadia Y.A. Alaidaroos, Amr Alraies, John S. Colombo, Lindsay C. Davies, Rachel J. Waddington, Alastair J. Sloan, Ryan Moseley

Dental Medicine Faculty Research

Human dental pulp stem/stromal cells (hDPSCs) derived from the permanent secondary dentition are recognised to possess certain advantageous traits, which support their potential use as a viable source of mesenchymal stem/stromal cells (MSCs) for regenerative medicine-based applications. However, the well-established heterogeneous nature of hDPSC subpopulations, coupled with their limited numbers within dental pulp tissues, has impeded our understanding of hDPSC biology and the translation of sufficient quantities of these cells from laboratory research, through successful therapy development and clinical applications. This article reviews our current understanding of hDPSC biology and the evidence underpinning the molecular basis of their heterogeneity, which …

Survival Rate Of Dental Implants Placed In Alveolar Ridge Preservation Sites - Systematic Review, Sravanthi Papisetti

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: It is not known so far performing Alveolar Ridge Preservation (ARP) in a freshly extracted socket with intact walls would improve clinical outcomes of implants placed in these sites. It is not known whether different biomaterials and techniques would affect the survival of dental implants.

Aim: The current systematic review is undertaken to assess the survival rate of dental implants placed in these sockets and to assess different socket graft materials as well as techniques of ridge preservation with regard to the survival of implants.

Material methods: Search for relevant articles was done in Medline (PubMed). No …

Zonulin As A Mediator Of Psychological Stress And Periodontal Disease, Casey D. Wright

Graduate Theses, Dissertations, and Problem Reports (ETD)

The prevalence of chronic inflammatory diseases is on the rise. Some have posited the permeability of tight junctions in gastrointestinal epithelium tissues as a potential mechanism for precipitating inflammatory processes throughout the body. Zonulin is the only known modulator of tight junction permeability and has been implicated in numerous chronic inflammatory processes (e.g., proinflammatory cytokine production) and diseases, more generally. The role of zonulin in oral inflammation, however, has yet to be explored. Periodontal disease is the most common oral inflammatory condition and primary perpetrator of tooth loss. Periodontal disease also is associated with a number of other health problems …

Comparative Analysis Of Gene Expression Patterns For Oral Epithelial Cell Functions In Periodontitis, Octavio A Gonzalez, Sreenatha Kirakodu, Linh M Nguyen, Luis Orraca, Michael J Novak, Janis Gonzalez-Martinez, Jeffrey L Ebersole

Faculty, Staff and Student Publications

The structure and function of epithelial cells are critical for the construction and maintenance of intact epithelial surfaces throughout the body. Beyond the mechanical barrier functions, epithelial cells have been identified as active participants in providing warning signals to the host immune and inflammatory cells and in communicating various detailed information on the noxious challenge to help drive specificity in the characteristics of the host response related to health or pathologic inflammation. Rhesus monkeys were used in these studies to evaluate the gingival transcriptome for naturally occurring disease samples (GeneChip® Rhesus Macaque Genome Array) or for ligature-induced disease (GeneChip® Rhesus …

Evaluation Of Different Scaffolds For Bone Regeneration In Rat Calvarial Bone Defects, Jeerawit Sirakittiworapong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Scaffold plays a key role in the context of tissue engineering. It not only provides a structural support for cells, but also creates an appropriate milieu for recruited cells, enhancing the therapeutic effects of cell-based treatments, and enabling the controlled release of biological cues such as growth factors. Collagen is widely used scaffold material in tissue engineering, particularly in periodontal and bone regeneration. Other natural polymers, however, have been developed and can be useful. Therefore, in this study, we aim to investigate the ability of four different natural polymers including collagen, chitosan, silk fibroin, and silk fibroin/gelatin hydrogel in promoting …

Protein Expression After Gingival Injection Of Messenger Rna Encoding Platelet-Derived Growth Factor-Bb In Ligature-Induced Rat Periodontitis, Pimphorn Meekhantong

Chulalongkorn University Theses and Dissertations (Chula ETD)

As a new class of medicines, mRNA platform has proven to be safe and effective. The objective of this study was to investigate the effect of local inflammation on platelet derived growth factor-BB (PDGF-BB) expression after gingival injection of PDGF-BB mRNA in lipid nanoparticles (LNPs) in ligature-induced rat periodontitis and to examine the dose-dependent effect of gingival delivery of mRNA. 3-0 silk was placed around maxillary left second molar for two weeks and removed, while the corresponding molar on the right was non-ligated. Under stereomicroscope, a significant bone loss at ligature sites was observed as compared to the non-ligature sites, …

Peri-Implantitis Incidence And Effect Of Supportive Periodontal Therapy On Outcomes: Retrospective Cohort Study, Michael Ha

Theses and Dissertations

Purpose: Management of peri-implantitis is becoming an increasing component of dental practice. Dental implants can develop peri-implantitis lesions which occur in a non‐linear and accelerating pattern compared to a gradual periodontitis lesion. It is crucial to diagnose and treat this disease early, or ideally prevent it. Contemporary implants have a rough surface texture which is difficult to properly decontaminate as a crucial component for treatment prognosis. Evidence on the long-term effects of Periodontal implant maintenance therapy (PIMT) on implants is limited. This study aims to investigate the effect of periodontal maintenance on peri-implant tissue health.

Methods: A retrospective chart review …

Exploring Dynamic Navigation For Palatally Impacted Canine Uncovery Surgery., Daniel Joseph Hall

Theses and Dissertations

Purpose: The objective of this study was to compare the exposure/uncovery of palatally impacted canines via the use of dynamic navigation guidance to the traditional freehand approach. Outcomes evaluated include the time to plan and perform exposure, area/size of initial access to locate the impacted tooth and the final size of the osteotomy to completely uncover the impacted tooth.

Methods: In order to simulate various frequently encountered clinical scenarios, three different model types were used. Six plastic models of each model type were fabricated from epoxy resin. Each model contained 2 bilaterally, palatally impacted canines, that were randomly embedded in …

Management Of Severe Dento-Alveolar Traumatic Injuries In A 9-Year Old Boy: A Case Report, Elnaz Mousavi, Masoomeh Khoshdel, Hamidreza Sharifiyan

Journal of Dentistry Indonesia

Dentoalveolar traumas can lead to various injuries that may result in tooth loss. A suitable treatment plan and appropriate interventions should be performed to maintain the dental function and aesthetics, especially for the anterior teeth. Objective: To report the interventions performed on dentoalveolar trauma on a 9-years old male patient who presented with gingival immersion of the right maxillary central incisor and missing a tooth due to a falling accident. Case Report: The patient had multiple traumatic injuries. The medical and dental history was taken, and the clinical and radiologic examinations were performed. The patient underwent surgical intervention and splinting …

Association Among Hscrp Levels, Bone Mineral Density, And Periodontal Parameters In Postmenopausal Women, Aastha Baldodia, Rajinder Kumar Sharma, Shikha Tewari, Aman Arora

Journal of Dentistry Indonesia

Association of Osteoporosis and periodontitis is well documented. Osteopenia being the initial state of bone loss prior to osteoporosis; finding its correlation with clinical attachment loss holds significance in the process of establishing early reduction in BMD as a risk factor for periodontitis. Objectives: The present cross sectional study aimed to explore the association of osteopenia with serum high sensitivity C-reactive protein (hsCRP) levels, and periodontal parameters in narrow age range postmenopausal (PM) women. Methods: 112 participants in this single centred cross sectional study were bifurcated into test group: osteopenic PM women [n=62], and control group: normal bone mineral density …

Antibacterial And Antibiofilm Efficacy Of Pineapple Hump (Ananas Comosus) On Porphyromonas Gingivalis In Vitro, Abdul Gani Soulissa, Billy Lombardo, Armelia Sari Widyarman

Journal of Dentistry Indonesia

Background: Periodontal disease is one of the most prevalent oral health problems in Indonesia that affects supporting tissues of the teeth. Porphyromonas gingivalis plays an important role in the pathogenesis of periodontal disease. Alternative therapy with natural plant extracts, including pineapple (Ananas comosus) hump extract may inhibit the growth of bacteria that cause periodontal disease. Objective: To determine the effect of pineapple hump extract on bacterial growth and adhesion of Porphyromonas gingivalis biofilms. Method: The bacterial inhibition test was performed by the agar well diffusion method, and biofilm density measurements were made using the biofilm assay method. Results: Pineapple hump …

The Effect Of Parabiotic Reuterin On The Expression Of Genes Involved In Candida Albicans Biofilm Formation: An Ex Vivo Study, Anastasya Muna Riad, Armelia Sari Widyarman

Journal of Dentistry Indonesia

Candida albicans has a number of properties, including resistance to various antimicrobial agents, which allow it to survive in the root canals. Lactobacillus reuteri plays a role in maintaining oral health through interactions with the oral microbiome. L. reuteri has potential as a preventive and therapeutic agent against inflammatory diseases. Objective: The aim of this study was to investigate the effect of irrigation with a reuterin-containing solution on BCR1, ACE2, EFG1, and TEC1 gene expression in C. albicans root canal biofilms. Methods: L. reuteri was cultured in MRS broth and incubated anaerobically for 24 hours at 37°C. C. albicans was …

Effects Of Different Finishing Procedures On Surface Roughness Of Hybrid Cad/Cam Materials, Ender Akan, Ozlem Colgecen, Ibrahim Talha Meşe, Bora Bağiş

Journal of Dentistry Indonesia

Hybrid ceramics combine the beneficial properties of resin with the advantage of glass ceramics. However, there are limited study about on roughness properties of hybrid materials. Objective: To investigate of the effects of surface finishing methods on roughness of dental restorations made from hybrid CAD/CAM blocks. Methods: A total of 60 samples were produced (n=20) for three main material groups, two different hybrid ceramic (LAVA Ultimate and VITA Enamic) and a conventional glass ceramic (IPS e.max CAD). Each material group was divided into two subgroups (n=10). Ten samples were polished and 10 were glazed according to related manufacturer instructions. Surface …

The Effect Of Omega-3 Polyunsaturated Fatty Acids On Periodontal Inflammation In Rats, Hardev M. Singh

Loma Linda University Electronic Theses, Dissertations & Projects

Aim: The aim of this study was to evaluate any possible beneficial effects of omega-3 polyunsaturated fatty acids (Ω-3 PUFAs) as a dietary supplement when incorporated into the diet of rats that had periodontitis induced via a ligature model.

Materials and Methods: 20 male rats (Sprague Dawley) were divided into 2 groups as following: 1) Control group with ligature-induced periodontitis and no Ω-3 PUFA in the diet; and 2) Test group with ligature-induced periodontitis and Ω-3 PUFA introduced in the diet. The ligature was placed around the mandibular first molars in the gingiva sulcus for a period of …

The Interleukin-17 (Il-17) Concentration In Saliva Of Patients With Oral Lichen Planus, Mai Talaat Elgendi, Radwa Ragheb Hussien, Ahmed Abdel Aziz Hassan, Olfat Shaker

Future Dental Journal

Background: The aim of the present study was to measure the clinical and pain score in these patients and to measure the level of IL-17 in saliva of patients having different forms of Oral lichen planus lesions (OLP).

Subjects and methods: According to sample size calculation, the present study was done on a total of 40 subjects divided into 3 groups Group (I) Twenty patients having erosive/atrophic OLP. Group (II) Ten patients having reticular OLP and Group (III) Ten healthy control patients. Salivary samples were collected from the subjects of the three groups to evaluate the levels of IL-17 using …

Clinical Periodontal Assessment Following The Adjunctive Use Of Lycopene And Vitamin C In Non Surgical Therapy Of Chronic Periodontitis: A Randomized Clinical Trial, Nevein Mohammed Osama Algammal, Nivine Ibrahim Ragy, Mohammed Wagdy Bissar, Mohammed El-Mofty

Future Dental Journal

Objective: To evaluate the clinical outcome of chronic periodontitis patients by clinical measurement of pocket depth (PD) and clinical attachment level (CAL) following non-surgical periodontal treatment with adjunctive use of lycopene and vitamin C.

Subjects and Methods: 42 eligible systemically healthy patients with chronic periodontitis assigned to each group after assessment of clinical parameters plaque index (PI), gingival index (GI), probing depth (PD), clinical attachment loss (CAL), were recorded. Cases were allocated into 3 groups by computerized randomization, 14 patients each group (n = 14). Group I (Lycopene): patients were supplemented with 10 mg lycopene soft gels once daily for …

Evaluation Of Locally Delivered 1.2% Atorvastatin Gel Versus 2% Melatonin Gel As Adjunctive To Non-Surgical Periodontal Therapy On Gcf Osteocalcin Level In Stage Ii Periodontitis Patients: A Randomized Controlled Trial, Sarah Gamal Moussa

Future Dental Journal

Abstract:

Objective: Atorvastatin (ATV) and melatonin have antioxidant and anti-inflammatory properties and were suggested to have positive effects when used in periodontitis cases. In periodontitis, osteocalcin (OC) was suggested to be a bone formation marker. Regarding bone turnover in periodontium, gingival crevicular fluid (GCF) osteocalcin levels are more accurate than salivary or serum levels.

Aim: The aim of the present study was to assess the effectiveness of local delivery of ATV gel and melatonin gel as adjuncts to scaling and root planing (SRP) in the treatment of stage II periodontitis patients.

Subjects and method: Thirty-six patients having stage II periodontitis …

Congenital Epulis: A Two-Case Report, Monica Ivanov, Bianca Stroe, Valeriu Ardeleanu, Razvan Hainarosie, Vlad Denis Constantin, Anca Silvia Dumitriu, Stana Paunica, Anna Kadar

Journal of Mind and Medical Sciences

Congenital epulis is a rare benign tumor of the newborn that could be detected in the prenatal period. Females are more often affected than males and the premaxillary region is usually the predilection site for this oral mass. Excision is the treatment of choice and no recurrences have been reported so far.

We present our experience with two cases of congenital epulis, detected in the second trimester of gestation and treated shortly after birth with no further complications. Histopathology should differentiate between congenital epulis and other congenital oral tumors even if its clinical appearance is usually enough to make a …

Bacterial Biofilm Growth On Various Dental Stabilization Systems For Avulsed And Luxated Teeth, Mahmoud Mona, Clay Walker, Luciana M. Shaddox, Roberta Pileggi

Oral Health Practice Faculty Publications

With the increased incidence of traumatic injuries and the advanced understanding of the periodontal and alveolar healing process, teeth splinting has become a common practice for stabilizing traumatized teeth. Consequently, several splinting materials and techniques have been introduced in the past few years. Despite the detrimental role of bacterial biofilm on healing, the level of biofilm development on these material surfaces has not been well investigated. Bacterial biofilms are severely detrimental for periodontal healing of avulsed and luxated teeth. Thus, biofilm growth becomes a critical factor in selecting the material of choice for dental splints. In this study, we aim …

Interrelationship Between Orthodontics And Implantology In Anterior Aesthetic Rehabilitation: A Case Report, Adailton De Morais Cavalcante, Renata Cordeiro Teixeira Medeiros, Danilo Lopes Ferreira Lima, Saulo Ellery Santos

Journal of Dentistry Indonesia

The rehabilitation of complex cases in the anterior region of the maxilla may require knowledge of several dental specialties. when dental involvement also causes bone and gingival involvement, management usually requires adjustment of gingival zenitis and bone graft to compensate for bone loss.

Objective: to discuss a case of previous orthodontic treatment for implant-prosthetic rehabilitation in the anterior region.

Case report: This case report describes a 40-year-old patient who came with the intention of extracting the tooth and installing a bridge. The implant-prosthetic treatment was performed after previous orthodontic treatment to adapt the gingiva and space.

Conclusion: The interrelationship of …