Alternative and Complementary Medicine Commons^™

Research Highlights, Annie Valentina

Indian Journal of Research in Homoeopathy

Research Highlights

Utility Of Individualised Homoeopathic Medicines In Improving Social Interaction In Childhood Autism: A Prospective, Open-Label, Single Arm Study, Sreeja Kudukayil Radhakrishnan Nair, Deepthi Gilla, Mohan Narvelil Devasia

Indian Journal of Research in Homoeopathy

Background: Childhood autism is a pervasive developmental disorder. There has been an upsurge in its prevalence in past few decades. The social deficit is the most disabling symptom of autism. There is an immediate need to explore new interventions to effectively address childhood autism. Objective: The objective of the study was to assess the usefulness of individualised homoeopathic medicine in improving social interaction in childhood autism. Materials and Methods: This one-year duration study was conducted in the outpatient department of the National Homoeopathy Research Institute in Mental Health, Kottayam, Kerala. Thirty-five children fulfilling the diagnostic criteria of childhood autism (as …

Book Review On "Homeopathy For Farm And Garden", Hima Bindu Ponnam

Indian Journal of Research in Homoeopathy

Book review on "Homeopathy for Farm and Garden"

Providing End-Of-Life Counseling: A Narrative Inquiry, Carol Hecht, Sibyl West

Adultspan Journal

This qualitative study aimed to address the gap in the research related to end-of-life counseling by exploring the experiences of counselors working with clients at end of life. While counseling literature and education are lacking regarding end of life, many counselors will work alongside clients approaching death. The purpose of this study was twofold: (a) to better understand the nuanced experiences of counselors providing end-of-life counseling and (b) to explore the supports and preparations helpful for counselors to provide end-of-life counseling. A narrative approach, using the Listening Guide (Gilligan, 2015), was employed to analyze and present the stories of three …

Considerations Of Medicare Telehealth Services With Older Adults, Sonah Kho, Amanda Dediego

Adultspan Journal

The onset of the COVID-19 pandemic set in motion a rapid expansion of mental health services offered via telehealth. With this rapid expansion came the need to examine how policy and practice should be shaped in a future where telehealth is considered common in counseling practice. For counselors to understand how to support older adult clients in using telehealth services, they must understand telehealth policy. Following the eligibility of licensed counselors to participate in Medicare, counselors need to stay abreast of regulatory changes regarding restrictions and regulations on use of telehealth for mental and behavioral health services, including video and …

Real-World Impact Of Acupuncture On Analgesics And Healthcare Resource Utilization In Breast Cancer Survivors With Pain, Dina Quan Ng, Sanghoon Lee, Richard T. Lee, Yun Wang, Alexandre Chan

Pharmacy Faculty Articles and Research

Background

This study evaluated the real-world impact of acupuncture on analgesics and healthcare resource utilization among breast cancer survivors.

Methods

From a United States (US) commercial claims database (25% random sample of IQVIA PharMetrics® Plus for Academics), we selected 18–63 years old malignant breast cancer survivors experiencing pain and ≥ 1 year removed from cancer diagnosis. Using the difference-in-difference technique, annualized changes in analgesics [prevalence, rates of short-term (< 30-day supply) and long-term (≥ 30-day supply) prescription fills] and healthcare resource utilization (healthcare costs, hospitalizations, and emergency department visits) were compared between acupuncture-treated and non-treated patients.

Results

Among 495 (3%) acupuncture-treated patients (median age: 55 years, stage 4: 12%, average 2.5 years post cancer diagnosis), most had commercial health insurance (92%) and experiencing musculoskeletal pain (98%). Twenty-seven …

Autonomic Nervous System And Viscera-Related Responses To Manual Therapy: A Narrative Overview, Murdi Alanazi, Brian Degenhardt Do, Gwyn Kelley-Franklin, Eric Jacobson, Sandy Fritz, Norman Kettner, Vaclav Kremen, Laura Lipke, William Reed

Library Scholarship

Background: Manual therapy (MT) has long-held that it physiologically impacts autonomic nervous system (ANS)and viscera-related function. This narrative review is intended to serve as a consolidated interdisciplinary resource of original studies related to physiological effects of MT as it relates to the ANS for MT clinicians and researchers new to this MT-related topic.

Objective: This review seeks to identify ANS and viscera-related physiological responses to MT interventions using search terms commonly used by chiropractic, massage, osteopathic, physical therapy, and structural integration clinicians and to provide a quick reference resource of original MT-related studies investigating ANS effects.

Methods: For this interdisciplinary …

Synthesis, Antiproliferative Activity And Molecular Docking Studies Of Neo‑ And Isocryptolepine Conjugates, Asmaa Taha

Nanotechnology Research Centre

A series of twelve conjugates 9a-c, 10a-c, 11a-c, and 12a-c based on naturally occurring neo- and isocryptolepines I and II were synthesized and characterized. The synthetic pathways involved nucleophilic substitution reaction of the preprepared amines 4a-c and 5a-c with 1-(4-bromobutyl)indole derivatives 8a and 8b, respectively, in aprotic solvent under heating. The structures of the synthesized conjugates were elucidated by FTIR, ¹H NMR, ¹³C NMR, and MS spectrometry and showed data consistence with the expected structures. The antiproliferative activity of 9a-c, 10a-c, 11a-c and 12a-c was evaluated against HepG-2 and HCT-116 cancer cell lines using normal …

In Silico Modelling And Docking Simulation Of Egfr-Targeted Diphtheria Toxin Chimera With Various Targeting Moieties, Muhammad Afif Naufal Bmed, Benedictus Ansell Susanto Bmed, Talitha Dinda Gunawan Bmed, Azhar Ridha Lukman Bmed, Alifa Rahma Rizqina Bmed, Muhammad Misbahul Fuad Bmed

Indonesian Journal of Medical Chemistry and Bioinformatics

Introduction: Cancer is a major etiology of death worldwide due to high mortality and suboptimal medicine. However, an emerging field, targeted therapy enabled a more selective and effective therapeutic action. This article aims to analyze in-silico the hypothetical targeted therapy agent that is combinations of conjugate consisting of EGFR targeting moieties and diphtheria toxin (DT-390).

Method: Our novel peptide is a conjugate of a novel EGFR targeting peptide and DT-390, forming a chimera. The tertiary structure was predicted using AlphaFold 2.0. The best IDDT scoring and stereochemistry profiles were utilized. The HADDOCK2.4 webserver modelled the docking between our …

The Prospect Of Indonesian Herbal As An Alternative Treatment For Covid-19 Patient: A Literature-Based Study, Hadi Sunaryo, Wahyu Hidayati

Indonesian Journal of Medical Chemistry and Bioinformatics

Coronavirus disease 2019 (COVID-19) is a new disease caused by a novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The disease has several symptoms from mild to severe and could lead to death for comorbidities and the elderly. Therefore, the infections and mortality cases keep growing day by day, moreover many authorities are trying to suppress it by applying several health protocols, including medicines. Several studies were conducted on drug discovery from plants to cure the disease. The article aimed to do a narrative review about the prospect of JAMU becoming an alternative medicine to cure COVID-19 by mapping …

Metabolite Biomarker Discovery For Lung Cancer Using Machine Learning, Ariski Fajarido, Linda Erlina, Aryo Tedjo, Fadilah Fadilah, Wawaimuli Arozal

Indonesian Journal of Medical Chemistry and Bioinformatics

Lung cancer is the leading cause of cancer death worldwide. About 2.1 million lung cancer patients were diagnosed in 2018, accounting for about 11.6% of all newly diagnosed cancer cases. For lung cancer, blood is the first choice as a source of screening biomarker candidates. Blood biomarkers provide a snapshot of the patient's entire body, including the primary tumor, metastatic disease, immune response, and peritumoral stroma. However, sputum sampling, bronchial lavage or aspiration, exhaled breath (EB), and airway epithelial sampling represent unique samples for lung cancer and other airway cancers as potential sources for alternative biomarkers. Metabolites are products of …

What Are The Most Effective Non-Pharmacologic Practices For The Management Of Primary Insomnia In Adults?, Alexis Myhre

Theses and Graduate Projects

Objective: Primary insomnia is a mental health condition in which individuals struggle with falling asleep, staying asleep or early morning awakenings. As there are many treatments available that claim to help those with primary insomnia, this review looks specifically at therapy, exercise and acupuncture as management strategies.

Methods: This is a review of 15 peer-reviewed, randomized controlled trials completed in 2018 or later with one additional study completed in 2010. Also, there are four non primary insomnia based studies used to support the efficacy of alternative therapies to cognitive behavioral therapy (CBT). All the studies used in this review come …

The Efficacy Of Cannabis As A Substitute Addiction For Opiates, Clark Furlong

Theses and Graduate Projects

Background: Approaches to opiate addiction focus on abstinence and/or a harm reduction model that often utilizes substitute medications. Methadone and suboxone are the most prescribed drugs for opiate maintenance therapy. The long-term side effect profile and health consequences are undesirable. Research is looking for healthier alternatives.

Purpose: Opiate maintenance therapy participants have a mortality rate greater than twelve times that of the normal population, we seek to discover if cannabis can be a useful/safer alternative.

Methods: Following a comprehensive literature review a 7-question online survey was designed with SurveyMonkey to gauge current Augsburg students’ perception of cannabis as an alternative …

Awareness Of Nutrition's Impact On Mental Health And Ketogenic Diet’S Therapeutic Potential For Mental Illness And Other Chronic Disorders, Innocent Nsengiyumva

Theses and Graduate Projects

Mental health affects millions of people worldwide, and current pharmaceutical treatment approaches often lead to worse outcomes, weight gain, and increased cardiovascular risk. The ketogenic diet offers hope in the treatment of schizophrenia and other neurological and psychiatric disorders. The aim of this project is to explore public awareness of nutritional psychiatry and the ketogenic diet’s clinical utility for various conditions including schizophrenia, mood disorders, Parkinson’s, and multiple sclerosis. Study participants (n=108) completed a 12-question survey about individual nutritional habits and current knowledge of KD. Responses were obtained from medical students, practicing healthcare professionals, college undergraduate students, and members of …

Increasing Occupational Engagement In Adults With Anxiety And Depression Through Martial Arts, Alfred Franklin, Keisa Boykin

Summer 2024 OTD Capstone Symposium

This poster is for a capstone project that developed a martial arts program for adults with anxiety and depression to increase occupational engagement in these individuals.

Guided-Imagery Meditation As An Adjunct To Weight Management, Karen Roddy, Nancy Hamler, Niraj Bangari, Eva Lukas

Pacific Journal of Health

Objective: To assess the utility of guided imagery meditation (GIM) as a low-invasive, cost-effective modality to weight management. Researchers hypothesized that using a standardized, lifestyle-focused GIM would result in weight loss and waist circumference (WC) changes.

Design: Researchers designed a 12-week randomized, controlled pilot study in which participants were asked to use a provided GIM.

Setting: Comfort and relaxation are crucial for GIM. The study, therefore, utilized participants’ personal environments.

Participants: Convenient sampling of 82 students, faculty, and staff of the University of the Pacific.

Intervention(s): Intervention group participants were provided with a researcher-designed, lifestyle-focused …

Cruising Speed: Our Journal's 10-Year Voyage, Dennis J. Baumgardner, Joe Grundle

Journal of Patient-Centered Research and Reviews

In this invited editorial, two long-tenured editors for the Journal of Patient-Centered Research and Reviews recount the publication’s many impactful contributions to the medical literature over its first 10 years.

Towards Addressing Mental Health In Rural Louisiana: Blueberry Supplementation As A Natural Intervention, Katy E. Venable

LSU Doctoral Dissertations

Depression and anxiety are major public health issues; however, there is an unmet need for novel effective and accessible treatments, particularly in rural communities. Blueberries are an unexplored nutraceutical for these conditions due to their excellent nutritional profile, with particularly high levels of polyphenols and anthocyanins and benefits on mood, cognition, and health. Therefore, we conducted a double-blind, randomized pilot study in a rural population. We employed a cross-over design to test the effects of 12 weeks daily ingestion of 24 g of whole freeze-dried blueberry powder versus placebo on symptoms of depression and anxiety in those diagnosed with depression …

Improving The Integration Of Whole Health Into A Veterans Affairs Outpatient Primary Care Clinic., Diana Lynn Blair

Doctor of Nursing Practice Papers

Abstract

The annual $4.1 trillion price tag for healthcare with a simultaneous decline in patient health outcomes is the catalyst to change the current healthcare culture from disease-focused to a Whole Health wellness and prevention model. Transforming to preventative care would remedy the current costly healthcare system, thus Veterans Health Administration (VHA) set forth a mandate to implement Whole Health (WH) system wide. The purpose of this project was to provide a training program that facilitated the implementation of WH and improve the documentation of WH in the electronic health record (EHR). A needs assessment provided to the Fort Knox …

T. Boudieri Extract Potentiates The Effects Of Capecitabine Treatment In Human Colon Cancer Cells, Katia Sawaya, Mahmoud Khalil, Ghada Khawaja

BAU Journal - Science and Technology

Resistance to chemotherapy remains a major challenge for colorectal cancer patients worldwide, hence the persistent need to uncover alternative treatments as well as new adjunct therapies in the fight against cancer. Natural extracts constitute an excellent source of bioactive substances that have a promising potential in that regard, with minimal negative side effects. We have previously demonstrated that both the ethanolic as well as the water extracts of Terfezia boudieri, a black desert truffle abundant in and part of the cuisine of the Mediterranean region, have significant antiproliferative effects against colon cancer cells. Our aim in this study was …

Increasing The Efficiency Of Lifestyle Medicine Counseling: A Visual Approach, Kayla A. Hinton, Ryan Smith

HCA Healthcare Journal of Medicine

Too much to counsel on, too little time? We would like to present a unique and innovative perspective on lifestyle medicine counseling through the lens of a homemade flyer, designed to bridge the gap between conventional health care practices and personalized, holistic well-being. In the promising field of health care humanities, the homemade lifestyle medicine flyer serves as a tangible manifestation of individual agency in promoting health and vitality. The flyer encapsulates a diverse range of self-care practices, dietary insights, and mindfulness techniques, emphasizing the inherent connection between mind, body, and spirit in one’s health journey.

This double-sided document highlights …

Reporting Clinical Cases: Advancing Homoeopathy, One Case At A Time, Subhash Kaushik

Indian Journal of Research in Homoeopathy

Case reports have been invariably contributing to the research world in their own way. They remain a popular genre among the readers, especially the clinicians who lay their hands upon a clinical journal with an interest to pick new knowledge about a certain disease or a drug than to learn about new evidence generated through statistical calculations. Its presence in medical literature is reported to be quite ancient, with some evidence dated back to the Egyptian antiquity. In fact, a well-documented case report is a representative version of many similar clinical success stories.

Management Of Psychosis With Individualised Homoeopathic Medicines: A Case Series, Karunakara Moorthi, Susu Pertin, Mohan Narvelil Devasia

Indian Journal of Research in Homoeopathy

Background: Psychosis is a clinical syndrome. The main clinical signs of psychosis are delusion and hallucination. It is a crucial focus of diagnosis and treatment in neurologic and psychiatric practice since it functionally disturbs numerous psychiatric, neurodevelopmental, neurologic and medical diseases.

Case summary: The World Health Organization Quality of Life Scale and the Brief Psychiatric Rating Scale were used to evaluate the patients. The outcomes in all the cases suggested that homoeopathic treatment can play a significant role in easing psychotic symptoms and restoring the patient’s ability to understand. The most frequently prescribed medicines and potencies in these cases were …

Homoeopathic Treatment Of Oral Leucoplakia: A Case Report, Suraia Parveen, Zeeshan Ahmed

Indian Journal of Research in Homoeopathy

Introduction: Oral leucoplakia (OL), a premalignant lesion which is more frequently encountered in elderly people, is defined as a white lesion of the oral mucosa. Smoking is one of the most common risk factors. Conventionally, surgical excision is the most recommended treatment option for OL. Case Summary: A 55-year-old male presented with the complaint of a whitish lesion inside the left angle of the mouth (buccal mucosa) for the past 1½ years. The case was clinically diagnosed as OL. He was advised for surgical excision, but he preferred to go for homoeopathic treatment. Based on characteristic symptoms, repertorial analysis and …

Resolution Of Subdural Hygroma With Homoeopathy: A Case Report, Partha Pratim Pal, Tania Chatterjee

Indian Journal of Research in Homoeopathy

Introduction: Subdural hygroma (SDH) is a collection of cerebrospinal fluid in the subdural space which may be idiopathic, traumatic or post-surgical occurring mostly in elderly patients. Case Summary: A 42-year-old female reported an acute complaint of compressing headache. The headache persisted even after initial prescriptions of Ruta graveolens 30C and 200C, which did not alleviate the condition. Further evaluation was done with a computed tomography scan, which revealed left-sided SDH. Tuberculinum 1M was prescribed, but even though the pain subsided, profuse, watery discharge began to ooze from both the ears and nose, which eventually stopped spontaneously. After six months, the …

Management Of Post-Operative Breast Nodules With Homoeopathy: A Case Report, Nisanth K.M. Nambison, Smita N. Nambison, Abhishek D. Dwivedi, Nisha Chakravarty

Indian Journal of Research in Homoeopathy

Introduction: Palpable masses after mastectomy are commonly detected by patients or their physicians. Imaging of palpable masses is advised following a complete history and physical examination. This is a case of breast nodules occurring after the removal of cancerous tissue in the breast. Homoeopathy, with its holistic approach, can treat the disease by addressing its multifactorial origin.

Case summary: A 71-year-old female, diagnosed with post-operative breast nodules after surgical excision of mucinous carcinoma portion of the left breast, was treated with individualised homoeopathic treatment for six months with subsequent improvement. This case provides preliminary evidence for the potential usefulness of …

Homoeopathic Medicine Arsenic Album 200c In Treatment Of Plaque Psoriasis: A Case Report, Neha Nagar, Ravi K. Poswal, Ajay Kumar, Kanak Singhal

Indian Journal of Research in Homoeopathy

Introduction: Psoriasis is a non-communicable, chronic, mostly painful, disfiguring disease. It can have a negative impact on patients’ quality of life, which may occur at any age. The conventional treatment includes local and systemic therapies, as well as phototherapy. The need for treatment is usually lifelong as remission occurs quite frequently. Case Summary: We present here a case report of a 32-year-old woman with psoriatic lesions all over the body for 15 years with intolerable itching. The present case was completely cured after 1 year 6 months of regular treatment with individualised homoeopathic medicine without any adverse effects. After detailed …

Plantar Warts Treated With Homoeopathic Medicine Antimonium Crudum: A Case Report, Laijun Nahar, Ruma Debbarma

Indian Journal of Research in Homoeopathy

Introduction: Plantar warts are cutaneous lesions brought on by human papilloma virus infection. There is a range of alternative treatment available for it, including cryotherapy, chemical cauterisation, curettage, electrodessication and laser removal. However, a majority of these treatments can leave scars or may provide only temporary relief. Case Summary: A 19-year-old female presented with multiple, right-sided plantar warts and was successfully treated by a single, individualised homoeopathic medicine, Antimonium crudum 200C for two months. The improvement was assessed through photographs taken in subsequent follow-up visits. The case was monitored further for a period of six months without any recurrence. This …

Individualised Homoeopathic Treatment For Pilonidal Sinus: A Case Report, Sumit Paliwal, Laijun Nahar, Rachna Paliwal

Indian Journal of Research in Homoeopathy

Introduction: Pilonidal sinus is a very common inflammatory disease of the gluteal region. The most common site of occurrence is the natal cleft. It can cause discomfort, absence from work and social embarrassment. There is no single, widely accepted therapy available for this condition. In most cases, the treatment option for this disease is surgical intervention, but recurrences following surgery are common. Case Summary: A 15-year-old male patient reported discharge from the sinus cavity in the natal cleft along with pain and discomfort. Nitric acid, a homoeopathic medicine, was prescribed during the initial consultation and the patient was followed …

Diabetic Foot Ulcer Treated With The Homoeopathic Medicine Lachesis Mutus In Millesimal Potencies: A Case Report, Lalith Singh, Raja Manoharan, Niharika Shaw, Saleem Ansari

Indian Journal of Research in Homoeopathy

Introduction: Diabetic foot ulcer (DFU) is the most common neuropathic complication of diabetes. Uncontrolled diabetes and improper foot care lead to serious conditions like DFU from minor injuries. Regular dressing and proper foot care are required for its improvement. Patients are left with no other option than amputation of the limb. Dressing for a longer period seems not convenient and feasible at the patient’s end. DFU also has wet gangrene as one of its major complications. Case Summary: This case report presents a case of a diabetic patient complaining of a foot ulcer for the past nine years, following the …