Alternative and Complementary Medicine Commons^™

Development Of An Evidence-Based Aromatherapy Policy And Toolkit For An Inpatient Psychiatric Hospital, Mia Nie

Doctor of Nursing Practice Final Project Abstract

Purpose:The purpose of this project was to develop a comprehensive, evidence-based aromatherapy policy and toolkit to guide safe and standardized use of aromatherapy as a complementary intervention in inpatient psychiatric settings.

Background: Sleep disturbances are common among psychiatric inpatients, and non-pharmacologic interventions are increasingly prioritized to support holistic care (Sazawa et al., 2022). Aromatherapy has shown potential benefits; however, the absence of standardized policies creates variability in practice and raises safety concerns, particularly in high-acuity psychiatric environments.

Methodology: This quality improvement project focused on developing an organizational policy. A review of current literature and clinical guidelines informed the foundation …

Nurse Manager Perceptions Of Strategies To Overcome The Underutilization Of Nonpharmacological Pain Control Methods In Adult Acute Care, Landen M. Bonnell

Undergraduate Honors Theses

A basic patient right is to have pain adequately managed. However, research consistently indicates that many adult patients in acute care experience inadequately managed pain, which may contribute to adverse patient outcomes. Studies have shown that nonpharmacological pain management can lead to increased patient satisfaction, shorter hospital stays, and better patient outcomes. However, many barriers exist to nurses providing effective nonpharmacological pain control therapy, primarily including heavy workload and a lack of education and support. Currently, there is insufficient research on how to overcome these barriers. Four nurse managers with experience in nursing leadership were interviewed using a qualitative descriptive …

Health Practices And Use Of Traditional Medicine Among Asian Indian Immigrants In The United States: A Pilot Study, Parita Patel, Anil N.F. Aranha

Medical Student Research Symposium

Title: Health Practices and Use of Traditional Medicine Among Asian Indian Immigrants in the United States: A Pilot Study

Authors

Parita Patel, MPH¹; Anil N.F. Aranha, PhD^1,2

Medical Education¹, Internal Medicine², Wayne State University School of Medicine, Detroit, Michigan

Abstract

Background and Purpose: Traditional and alternative medicine (TAM), including Ayurveda, Homeopathy, Naturopathy, and home remedies, remains widely used among Asian Indian (AI) immigrants in the United States alongside Western medicine. Cultural familiarity, family influence, and perceived safety shape these practices. This pilot study examined TAM prevalence, patterns, and perceptions among AI immigrants and …

The Effects Of Dietary Interventions On Gut Microbial Balance In Healthy Adults: An Integrative Review, Miranda Demars

Senior Honors Theses

The goal of this review is to answer the question: What dietary changes are most effective in restoring gut dysbiosis in healthy adults? The gut microbiome (GM), a community of microorganisms that colonizes in the gastrointestinal (GI) tract, can become imbalanced, a condition known as dysbiosis, which is associated with an increased risk of dysbiosis-induced disease. Dysbiosis-induced diseases include GI disorders such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), neurological disorders such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), and metabolic disorders such as diabetes and obesity (Shen et al., 2025). Pharmacologic interventions are often not …

Engagement Patterns With #Naturalremedies On Tiktok: Formative Analysis, Apeksha Mewani, Corey H. Basch, Keanu Renne-Glover, Vincent Jones Ii, Cristiana Cordero, Adea Gutiqi

Publications and Research

This research letter provides formative evidence from a cross-sectional analysis of 118 TikTok videos under #NaturalRemedies, identifying content formats and expertise cues associated with higher engagement, while also demonstrating the feasibility of using engagement metrics and thematic coding to analyze health narratives on emerging platforms such as TikTok.

Humanity Is Evolving Its Consciousness: The Role Of Archetypal Energies As Guides During An Unfolding Weeding Out And Alignment Process, Carroy U. Ferguson

Psychology Faculty Publication Series

Humanity is evolving its consciousness at individual and collective levels.  Given these seemingly tumultuous times, as of this writing (January 2026), to make such a statement may sound like a strange thing to say.  However, I suggest that if you are alive today and if you are reading these words, these are the very times for which you were born—to assist Humanity as it evolves its consciousness with your unique gifts, whatever they may be.  That is, this period of our individual and collective human being-ness may be characterized as an unfolding period of weeding out and alignment with the …

Moringa Oleifera As An Immunomodulator, Noha Swilam, Khaled A. Nematallah, Omayma Eldahshan'

Pharmacy

Moringa oleifera has gained increasing attention for its diverse pharmacological properties, including its potential to modulate immune responses. This chapter explores the immunomodulatory potential of M. oleifera, exploring both its phytochemical composition and experimental evidence from in vitro and in vivo studies. Key bioactive constituents, such as flavonoids (quercetin, kaempferol, apigenin), phenolic acids (chlorogenic, ferulic, caffeic), glucosinolates (glucomoringin) and their hydrolysis product, benzyl isothiocyanate, are identified as contributors to its immune-regulating properties. It has been demonstrated that these substances affect cytokine expression, suppress pro-inflammatory mediators, increase phagocytic activity and alter lymphocyte reactions. In order to support the plant's traditional use …

Beyond The Rabbit Hole: Dmt, Death, And The Hereafter, Abby Molina

Antioch University Dissertations & Theses

This dissertation explores a proposed relationship between death and N,N-dimethyltryptamine (DMT) within the context of contemporary clinical psychology and the current psychedelic renaissance. Building on Rick Strassman’s hypothesis that DMT may be released at the moment of death and Imants Barušs’ conceptualization of death as an altered state of consciousness, this project examines the phenomenological similarities between DMT-induced experiences (psychedelic “trips”) and near-death experiences (NDEs). Through review of neurobiological research, psychedelic-assisted therapy literature, religious and cultural ceremonial practices, and documented DMT trip and NDE reports, this work evaluates the plausibility that endogenous DMT contributes to altered states of consciousness observed …

The Impact Of A Social Wellness Intervention On The Perception Of Social Support Among Working Adults, Jannysse Gray

DNP Research Projects

Abstract 

Objective: Social isolation and loneliness have detrimental effects on physical and mental health. For working adults, these experiences may impact work attendance, performance, satisfaction, and retention, leading to burnout, fatigue, grief, and disengagement. Barriers to developing and nurturing healthy relationships, such as competing work and family responsibilities, or a lack of resources or energy, can contribute to this problem; therefore, this group was chosen for the intervention. This project aimed to raise awareness of the importance of social connections and to analyze whether an online educational intervention was associated with improved perceptions of social support among working adults. Methods: …

Role Of Plants And Phytochemicals In Promoting Proliferation And Osteogenic Differentiation Of Dental Mesenchymal Stem Cells: A Comprehensive Review, Hala El-Zahar, Essam Abdel-Sattar, Marwa Yousry Moustafa Issa, Shereen N. Raafat, Noha Swilam

Pharmacy

Abstract Objectives Dental mesenchymal stem cells (MSCs) represent a promising source for regenerative medicine due to their accessibility and capacity to differentiate into osteoblasts and other lineages. Osteogenic differentiation of dental MSCs is essential for bone formation and is regulated by multiple signaling pathways, cytokines, growth factors, and transcription factors. This review aims to summarize the effects of plant-derived extracts and phytochemicals on the proliferation and osteogenic differentiation of dental MSCs. Methods In this review, an extensive literature search was conducted covering studies from the past 10 years, using different online databases (SCOPUS, Google Scholar, PubMed, Web of Science, Science …

Mitigating Risk Of Premature Ovarian Insufficiency Using Adjunct Chinese Herbal Medicines: A Nested Patient-Control Study In Female Cancer Patients With Chemotherapy, Tzu-Ning Tseng, Hou-Hsun Liao, Hanoch Livneh, Ming-Chi Lu, Szu-Chin Li, Tzung-Yi Tsai

Leadership, Learning and Counseling Faculty Publications and Presentations

Premature ovarian insufficiency (POI) is a common late effect of chemotherapy among survivors of adolescent and young-adult cancer (AYAC). Given on the widespread use of Chinese herbal medicine (CHM) in restoring individual health, we performed a cohort-based nested patient-control study with the aim of exploring the effect of blending CHM into routine care on the reduction of chemotherapy-induced POIrisk among females with AYAC.

The Triangular Interaction Between Dietary Polyphenols, Gut Microbiota, And Metabolic Syndrome, Emily Bayliss

Senior Honors Theses

Type 2 diabetes mellitus (T2DM) is a growing global health concern characterized by peripheral insulin resistance as well as impaired insulin secretion from pancreatic β-cells. Emerging evidence suggests that the gut microbiome, specifically gut dysbiosis, an imbalance in the gut microbiome, is a critical modulator of the pathophysiology of T2DM. Dietary polyphenols, a diverse group of bioactive compounds that are abundant in plant-based foods, have recently gained attention for their potential to attenuate metabolic disorders through their antioxidant and anti-inflammatory properties as well as through modulating the composition and activity of gut microbes, thereby attenuating dysbiosis. However, the diabetic state …

Comparison Of Depression Risk And Depression-Related Ambulatory Care Utilization In Sarcopenia Patients With And Without Chinese Herbal Medicine., Hang-Che Li, Hanoch Livneh, Wei-Chiao Chang, Yu-Han Wang, Ming-Hsien Yeh, Bo-Chyuan Chen, Ming-Chi Lu, Wei-Jen Chen, Tzung-Yi Tsai

Leadership, Learning and Counseling Faculty Publications and Presentations

The impact of psychiatric disorder, especially depression, on the prognosis of sarcopenic patients is gaining prominence. Yet, there have been very few studies focusing on this issue, let alone the related targeted mental health prevention. This cohort-based nested case-control study is geared to compare risk of depression and the depression-related ambulatory care utilization for sarcopenia persons with and without receiving add-on Chinese herbal medicines (CHMs) treatment.

Real-World Evidence For Herbal Medicine Benefit In 9728 Type 2 Diabetes Patients-Peridonotitis Risk And Ambulatory Care Utilization., Wen-Wei Lin, Chieh-Tsung Yen, Hanoch Livneh, Hua-Lung Huang, Ming-Chi Lu, Wei-Jen Chen, Tzung-Yi Tsai

Leadership, Learning and Counseling Faculty Publications and Presentations

Recent evidence manifests that individuals with type 2 diabetes (T2D) are increasingly affected by oral disorders. Although medicinal herbs have shown promise in managing T2D, their benefit in managing periodontitis risk and subsequent healthcare utilization remains uncertain.

Untargeted Metabolomics Reveals Organ-Specific And Extraction-Dependent Metabolite Profiles In Endemic Tajik Species Ferula Violacea Korovin, Sylhiya Mavlonazarova, Kenneth Acosta, Rinat Abzalimov, Saidbeg Satorov, Vyacheslav Dushenkov

Publications and Research

Ferula violacea Korovin, an endemic Tajikistani plant with purported medicinal properties, remains understudied. This study employs untargeted metabolomics to characterize the metabolite profiles of ethanol extracts and juices from F. violacea roots and seeds. In total, 540 distinct metabolites are putatively identified, 419 of which are previously unreported in the Ferula genus, representing a substantial expansion of its known chemical diversity. The most abundant metabolites are terpenoids, amino acid derivatives, and alkaloids. A particularly abundant group of daucane sesquiterpenoids, sharing a common (6-methyl-azulen-4-yl) cyclohexanecarboxylate substructure, is identified, including known metabolites such as ferutidin and ferutinin. Comparative analysis reveals organ-specific metabolic …

The Science Of Sound: Studying The Cognitive, Emotional, And Physiological Effects Of Frequency, Genre, And Music, Jett Yarborough

Senior Honors Theses

Music influences emotion, physiology, and cognition, yet little is known about how the frequency it is tuned to affects these influences. Prior research has shown that music tuned to 432 Hz can reduce stress, lower blood pressure, and improve sleep. My colleagues and I conducted two studies to investigate this. Our research found that music tuned to 432 Hz promotes a significant increase in memory retention and induces a state of focus and relaxation. These results suggest that shifting from the standard tuning frequency of 440 Hz to 432 Hz could have a profoundly positive impact on our daily lives. …

Postsurgical Pain, Psychosocial Functioning, And Cannabis Use Among Adolescents And Young Adults Undergoing Gender Affirming Surgery, Eleanor Battison, Emily A. Kenyon, Corrin Murphy, Eline Lenne, Danielle N. Moyer, Sarah W. Feldstein Ewing, Anna C. Wilson

School of Social Work Faculty Publications and Presentations

Purpose: Little is known about transgender and gender expansive (TGE) adolescents and young adults (AYAs) pain and psychosocial experiences in the acute postsurgical period following gender-affirming surgery (GAS). This study describes pain symptomatology and psychosocial functioning within 1 month after GAS among TGE AYAs, examines immediate postsurgical associations of cannabis use with pain symptomatology, pain catastrophizing, and psychosocial functioning, and explores pain persistence, cannabis use, and psychosocial functioning in a subgroup of individuals 6 months after surgery.

Methods: AYAs (N = 64) underwent GAS at a large academic medical center in the Pacific Northwest between March 2019 and June …

Factors Associated With The Use Of Combined Nutritional Complementary And Alternative Medicine Among Southern Us Older Adults: Results From The Study Of Aging Ii, Kristen Allen-Watts, Deanna Rumble, Taylor Taylor, Andrew Sims, Lisa H. Antoine, Georgiana Logan, Cynthia J. Brown, Thomas W. Buford, Burel R. Goodin, Andrea Cherrington, Richard Kennedy

School of Medicine Faculty Publications

Background: Older adults use nutritional complementary and alternative medicine (CAM) to reduce the risk of (or treat) non-communicable conditions and diet deficiencies. While prior research has explored the individual use of dietary supplements, vitamins, and minerals among older adults, few studies have examined factors influencing the combined use of these modalities, especially among Southern, older adults in the United States. Methods: Data were extracted from 419 participants from the University of Alabama at Birmingham Study of Aging II, a population-based longitudinal study of mobility among community-dwelling older adults. Self-reported data, including insurance and rural residence status, was collected. Comorbidity burden …

Gallic, Aconitic, And Crocetin Acids As Potential Tnf Modulators: An Integrated Study Combining Molecular Docking, Dynamics Simulations, Admet Profiling, And Gene Expression Analysis, Adolat Manakbayeva, Ahdrey P. Bogoyavlenskiy, Timur Kerimov, Igor Yershov, Pavel Alexyuk, Madina Alexyuk, Vladimir Berezin, Vyacheslav Dushenkov

Publications and Research

Organic acids, as natural metabolites, play crucial roles in human metabolism and health. Tumor Necrosis Factor (TNF), a pivotal mediator in immune regulation and inflammation, is a key therapeutic target. We evaluated ten organic acids as TNF modulators using in silico molecular docking, followed by detailed ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) profiling and molecular dynamics (MD) simulations for three lead candidates: gallic, aconitic, and crocetin acids. Their effects on TNF gene expression were then assessed in vivo using a mouse leukocyte model. The in silico results indicated that crocetin had the highest TNF binding affinity (−5.6 to −4.6 …

Living Heritage, Resilience And Ethically Informed Infrastructures In Malawi, Martha B. Lerski, Frank Puluputu Mwale

Publications and Research

Rooted in a rural community’s needs, this paper explores how historically, and ethically informed infrastructures can support community engagement towards identification, documentation, and dissemination of local, traditional, and indigenous knowledge relating to climate change. The paper examines climate adaptation and sustainability issues through the lenses of community organizing and Library & Information Science best practices. It draws on a growing body of literature identifying a role for expanded epistemological and subject discipline perspectives. While the impacts of climate on material culture are increasingly recognized, intangible, and biocultural heritage have not received as much attention. Living heritage traditions and knowledge systems …

Personalized Pain Management Pathway Based On Individual Diagnoses, Tiana Bell Asn, Rn, Diana Desmornes Asn, Rn, Autumn Dwyer Bsn, Rn, Monica Foley Asn, Rn, Marissa Forleo Bsn, Rn, Heather Mcmillan Asn, Rn, Nicole Valenti Bsn, Rn

Posters

The intervention we’re proposing offers a comprehensive, individualized approach to pain management, taking into account diagnosis-specific pain scales, nonpharmacological interventions, and continued pain control post-discharge.

Impact Of Aromatherapy On Surgical Patients' Perceived Nausea And Vomiting, John Brennan, Ryan Brennan Bs, Sue Garrison Ma, Bsn, Rn, Cheryl Green, Evelyn Jacovino Msn, Rn, Cmsnl, Cynthia Martins Msn, Rn, Shelly Simonet Bsn, Rn, Jannet Serra Ma, Bsn, Rn, Beth Williams Dnp, Rn, Ec-Bc, Andrew Quito Bsn, Mba

Posters

Postoperative nausea and vomiting (PONV) is the most common adverse effect of surgery. In the United States, it is estimated that 20- 30% of all surgical encounters, or 75 million Americans yearly experience some form of PONV. Holistic management of PONV has the potential to save a significant amount of resources when compared to standard treatment modalities (Amirshahi et al., 2020; Asay et al., 2019).

Prior to implementation of this quality improvement project, it was estimated that roughly 20% of orthopedic surgery patients at Bridgeport Hospital Milford Campus experienced PONV, a serious practice concern. The goal of this project was …

To Heal A Mind: A Comparison Of Functional And Conventional Treatments In Major Depressive Disorder, Gillian Chambers

Senior Honors Theses

Incidence of major depressive disorder is increasing year over year, with little able to be done to halt the spread of the condition. However, there are many treatment possibilities considered unconventional by the healthcare system. This thesis examines the respective benefits and risks, in comparison to one another, between conventional pharmacological treatment and functional, holistic treatment of depression. This was done via integrative review of available clinical literature, synthesizing evidence on both conventional and functional treatments for depression, as dictated by Whittemore and Knafl (2005). Exploratory search methods revealed 758 records fulfilling inclusion criteria, which were screened and narrowed down …

Optimization Of Reaction Conditions For Synthesizing Kasa-Targeting Drug Candidates For Tuberculosis Treatment, Megan A. Baxter

Research and Creativity Symposium

Tuberculosis (TB) remains a global health challenge, with increasing drug resistance pressing for the development of novel treatments. KasA, a key enzyme in mycobacterial fatty acid biosynthesis, is a promising drug target for TB treatment. This research focuses on the design and synthesis of potential KasA inhibitors, specifically optimizing reaction conditions to efficiently produce 1-methyl-6-aminoindazole. This molecule is an intermediate in the synthesis of drugs targeting TB. Characterization of synthesized compounds is performed using NMR, mass spectrometry, and gas chromatography to confirm structure and purity. The first step involved optimizing the solvent and base for the methylation of nitroindazole. We …

Supporting Elementary Educators Through A Nervous System Regulation And Social-Emotional Learning Skills Workshop Intervention: An Musc Capstone Project, Lily Morgan

Entry-Level Occupational Therapy Doctorate - Doctoral Capstone Symposium

Teachers have a great influence on developing children’s emotional intelligence, regulatory capacity, and occupational engagement. These professionals also happen to report some of the highest rates of stress, mental health challenges (Agyapong, B. et al, 2022), and burnout (Xie, M., et al, 2022). Providing teachers with education and support on nervous system regulation, social-emotional learning skills, and related topics can improve their ability to manage job stress, enhance modeling and interactions with students, and improve their quality of life. This project aimed to enhance knowledge, provide access to resources, and serve to support elementary educators at an inner-city school in …

The Role Of Animals In Pediatric Occupational Therapy Telehealth Interventions: A Survey Of Therapist Perspectives., Macy Burr, Catherine Le

Occupational Therapy Collection

AIMS: Animal-assisted interventions (AAI) incorporate animals in health, education, or human services to improve participant health and well-being. AAI can decrease stress, increase happiness, and improve motor skills. During the COVID-19 pandemic, virtual AAI programs became more common. Telehealth also became more prevalent in occupational therapy. This study explored the perceptions of occupational therapy (OT) practitioners regarding including animals in telehealth OT pediatric interventions.

METHODS: Survey responses were collected from 18 occupational therapists who have included animals in OT pediatric telehealth interventions.

RESULTS: Most participants agreed that incorporating animals into telehealth enhanced the therapeutic experience for their clients, as they …

Using Musical Interventions As A Non-Pharmacological Strategy To Improve Chronic Pain Levels And Satisfaction Among Patients With Sickle Cell Disease, Fredeline Metellus

Doctor of Nursing Practice Final Project Abstract

Background

Sickle Cell Disease (SCD) is a chronic, inherited blood disorder characterized by severe pain episodes that are often poorly managed with standard pharmacological treatments. In response to patient dissatisfaction with pain control and the desire for holistic alternatives, this quality improvement project explored music therapy as a non-pharmacological pain management strategy.

Purpose

The primary aim was to reduce chronic pain by at least 20% and improve patient satisfaction with pain management among adults with SCD using a structured musical intervention.

Methodology

This project was implemented at a comprehensive outpatient SCD clinic using the Plan-Do-Study-Act (PDSA) model. Five adult patients …

Phytochemical Analysis And In Vivo Anticancer Effect Of Becium Grandiflorum: Isolation And Characterization Of A Promising Cytotoxic Diterpene, Christeen Fahim, Maha R. A. Abdollah, Rola Milad, Nehal Sabry, Noha Swilam

Pharmacy

Background:Becium grandiflorum is a fragrant perennial shrub of the Lamiaceae family. Objectives: The current study aimed to explore the cytotoxic potential of the nhexane fraction from Becium grandiflorum aerial parts and, further, isolate its major diterpene and conduct in vitro and in vivo anticancer activities along with its molecular mechanism and synergy with doxorubicin. Methods: The hydroalcoholic extract of Becium grandiflorum aerial parts was fractionated, and the n-hexane fraction was analyzed via GC-MS. The major isolated diterpene, 18-epoxy-pimara-8(14),15-diene (epoxy-pimaradiene), was quantified using UPLC-PDA. Cytotoxicity assays were conducted on HCT-116, MCF-7, MDA-MB- 231, and HepG2 cell lines. The synergistic effect with …

Cardiometabolic Benefits Of A Non-Industrialized-Type Diet Are Linked To Gut Microbiome Modulation, Fuyong Li, Anissa M. Armet, Katri Korpela, Junhong Liu, Rodrigo Margain Quevedo, Francesco Asnicar, Benjamin Seethaler, Tianna B. S. Rusnak, Janis L. Cole, Zhihong Zhang, Shuang Zhao, Adele Gagnon, Edward C. Deehan, Joao F. Mota, Jeffrey A. Bakal, Russell Greiner, Dan Knights, Nicola Segata, Stephan C. Bischoff, Laurie Mereu, Andrea M. Haqq, Catherine J. Field, Liang Li, Carla M. Prado, Jens Walter

Department of Food Science and Technology: Faculty Publications

Industrialization adversely affects the gut microbiome and predisposes individuals to chronic non-communicable diseases. We tested a microbiome restoration strategy comprising a diet that recapitulated key characteristics of non-industrialized dietary patterns (restore diet) and a bacterium rarely found in industrialized microbiomes (Limosilactobacillus reuteri) in a randomized controlled feeding trial in healthy Canadian adults. The restore diet, despite reducing gut microbiome diversity, enhanced the persistence of L. reuteri strain from rural Papua New Guinea (PB-W1) and redressed several microbiome features altered by industrialization. The diet also beneficially altered microbiota-derived plasma metabolites implicated in the etiology of chronic non-communicable diseases. Considerable …

Mindfulness-Based Interventions And Stress, Jacqueline Parker

Doctor of Nursing Practice Final Project Abstract

Purpose: Stress within the nursing profession is a substantial issue. Staff shortages, poor leadership, and even COVID-19 have contributed to an increase in nursing stress. Stress can negatively impact a nurse’s ability to perform at an optimal level while at work. The purpose of this project is to reduce perceived stress by implementing mindfulness-based interventions (MBI).

Background: The project was implemented in a twenty-three-bed unit that cares for the post operative pediatric population in Houston, Texas.

Methodology: A series of in-person and virtual educational lessons (eight total) on MBIs (with flyers) were implemented throughout this project. The Perceived Stress Scale …