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Full-Text Articles in Alternative and Complementary Medicine

Remedios De Abuela: Sacred Traditions Of Healing, Madeline R. Sardinas Apr 2025

Remedios De Abuela: Sacred Traditions Of Healing, Madeline R. Sardinas

be Still

Remedios de Abuela is a narrative-style essay reflecting on the Cuban remedies and family caregiving practices that shaped my journey into medicine. From the warmth of sopa de pollo to the soothing ritual of Vicks VapoRub, these traditions embody the sacred oath of healing.

Through personal stories, including caring for my grandfather with diabetes, this essay explores the intersection of family, culture, and the art of medicine. It is a tribute to my grandparents and a testament to the enduring power of traditions and the human connection at the heart of the healing profession.


Achieving Total Health Using Food To Heal: A Podcast On A Holistic Approach To Nutrition, Taylor Sharer Apr 2025

Achieving Total Health Using Food To Heal: A Podcast On A Holistic Approach To Nutrition, Taylor Sharer

Senior Theses

Nutrition is the key to a healthy and happy life. In a world where chronic, avoidable diseases are the leading cause of death, it is necessary to educate the public on how they can improve their overall health and wellbeing using food. Every aspect of health is interconnected, and what we eat can create massive changes in our health. My project focuses on holistic nutrition, providing an easily accessible, science-based and informative discourse about how to reach health and wellness goals through a podcast. Using personalized experience combined with current research, I discuss topics such as whole foods, individualized nutrition, …


The Effect Of Grape Seed Extract Against The Formation Of S.Aureus Biofilms In A Clinical Setting, Srestha Samaddar Apr 2025

The Effect Of Grape Seed Extract Against The Formation Of S.Aureus Biofilms In A Clinical Setting, Srestha Samaddar

Senior Theses

The rise of antibiotic-resistant bacterial infections, particularly those caused by Staphylococcus aureus, poses a serious threat to public health and clinical care. A major contributor to the persistence of these infections is the formation of bacterial biofilms, structured communities that protect S. aureus from antibiotics and immune responses, especially on surgical sites and medical devices. As conventional treatments become less effective, interest in alternative, natural antimicrobial agents has increased, due to public dissatisfaction with conventional medicine and a growing trust in complementary and alternative medicine. Grape seed extract (GSE), a polyphenol-rich byproduct of winemaking, has emerged as a promising candidate …


Efek Hipnoterapi Untuk Meningkatkan Kualitas Hidup Pada Pasien Penyakit Ginjal Kronik: Suatu Laporan Kasus Berbasis Bukti, Aisha Putri Chairani, Rudi Putranto, Hamzah Shatri, Maruhum Bonar Hasiholan Marbun, Edward Faisal, Vinandia Irvianita, Diah Martina Mar 2025

Efek Hipnoterapi Untuk Meningkatkan Kualitas Hidup Pada Pasien Penyakit Ginjal Kronik: Suatu Laporan Kasus Berbasis Bukti, Aisha Putri Chairani, Rudi Putranto, Hamzah Shatri, Maruhum Bonar Hasiholan Marbun, Edward Faisal, Vinandia Irvianita, Diah Martina

Jurnal Penyakit Dalam Indonesia

Chronic Kidney Disease (CKD) is a condition of kidney damage with a decrease in glomerulus filtration rate of 60 ml/min/1.73 m3 for a duration of more than three months. CKD is closely related to the patient’s quality of life because the patient must carry out various lifestyle restrictions to slow the progression of kidney damage. Lifestyle restrictions often cause problems in the psychosocial field that increase the severity of symptoms and decrease kidney function faster. This evidence-based case review was compiled to determine the effectiveness of hypnotherapy in improving the quality of life of CKD patients. Literature searches were conducted …


Identification Of Xanthine Oxidase Inhibitors In Single-Clove Black Garlic Using Metabolomics And Molecular Docking Approaches, Abdul Aziz Setiawan, Shirly Kumala, Dian Ratih Laksmitawati, Ari Yuniarto, Nancy Dewi Yuliana Mar 2025

Identification Of Xanthine Oxidase Inhibitors In Single-Clove Black Garlic Using Metabolomics And Molecular Docking Approaches, Abdul Aziz Setiawan, Shirly Kumala, Dian Ratih Laksmitawati, Ari Yuniarto, Nancy Dewi Yuliana

Makara Journal of Science

Black garlic is produced through controlled fermentation under specific temperature and humidity conditions, during which the Maillard reaction enhances its sensory properties and bioactivity. The anti-hyperuricemic potential of single-clove black garlic (SBG) remains unexplored. This study combined Ultra High-Performance Liquid Chromatography–High Resolution Mass Spectrometry-based metabolomics and an in-silico approach to identify the potential xanthine oxidase inhibitors (XOI) in SBG. Methanolic extracts (10 ppm) exhibited xanthine oxidase inhibition ranging from 50.09% to 68.01%, which is comparable to allopurinol (78.74%) at the same concentration. Metabolomic profiling tentatively identified 45 compounds, and orthogonal partial least squares analysis revealed seven metabolites as strongly correlated …


Combating Compassion Fatigue Using Mindfulness Techniques, Christie Baker, Summer Cross Mar 2025

Combating Compassion Fatigue Using Mindfulness Techniques, Christie Baker, Summer Cross

Student Scholarship & Creative Works

Demands placed on health care professionals have steadily increased and as a result, compassion fatigue has become an issue by adversely affecting the well-being of nurses and health care organizations. Compassion fatigue is a widely accepted phenomenon in nursing, creating an array of physical and emotional manifestations, impairing a health care provider’s ability to provide optimum quality care. The goal of this quality improvement project aimed to educate and provide emergency room nurses with a resource for self-care enhancement to subsequently decrease their risk of developing compassion fatigue. Nurses of a small, rural emergency department located in the southeastern region …


Application Of Quantum Entanglement To Explain The Healing Mechanism By Highly Diluted Homoeopathic Medicines, Bijay Krishna Chaudhuri, Biswadeep Chaudhuri Mar 2025

Application Of Quantum Entanglement To Explain The Healing Mechanism By Highly Diluted Homoeopathic Medicines, Bijay Krishna Chaudhuri, Biswadeep Chaudhuri

Indian Journal of Research in Homoeopathy

Background: The healing mechanism of highly diluted homoeopathic medicines (DHM) is not yet very clear.

Objectives: Our objective is to apply the concepts of entropy, information, and quantum mechanical principle of entanglement to find a model for explaining the healing mechanism of DHM.

Methodology: All living or non-living things are composed of dynamic microscopic quantum particles (electrons, protons, ions, etc.) which follow the basic properties of quantum mechanics such as quantum entanglement, superposition of quantum states and coherent interaction among these particles. The continuous change of thermodynamic entropies of the dynamic living cells leads to information change for cellular communication …


Effect Of Individualised Homoeopathic Intervention In Dyslipidaemia: An Open-Label, Randomised, Controlled, Exploratory Trial, Roja Varanasi, Rupali Bhalerao, Raveendar Ch, Raju Kolli, Ravi Sardala, R.V.R. Prasad, Paul Sumithran, M. Prakash Rao, Ramesh Dubashi, Kiranmayee R.G.R, S. Rajeeva, V. Sarathy, P.A. Rajakumari, Priyanka Srivastava, Anupriya Chaudhary, Gnnana Prakasham, P. Prasad, Arvind Kumar, Viqar A. Siddiqui, Praveen Oberai, Raj K. Manchanda Mar 2025

Effect Of Individualised Homoeopathic Intervention In Dyslipidaemia: An Open-Label, Randomised, Controlled, Exploratory Trial, Roja Varanasi, Rupali Bhalerao, Raveendar Ch, Raju Kolli, Ravi Sardala, R.V.R. Prasad, Paul Sumithran, M. Prakash Rao, Ramesh Dubashi, Kiranmayee R.G.R, S. Rajeeva, V. Sarathy, P.A. Rajakumari, Priyanka Srivastava, Anupriya Chaudhary, Gnnana Prakasham, P. Prasad, Arvind Kumar, Viqar A. Siddiqui, Praveen Oberai, Raj K. Manchanda

Indian Journal of Research in Homoeopathy

Background: Dyslipidaemia, the derangement of one or many of the lipoproteins is a major cause of cardiovascular events, causing 2.6 million deaths per year globally.

Objectives: This study evaluated the efficacy of individualised homoeopathic medicines with lifestyle modification in the management of dyslipidaemia.

Materials and Methods: This multicentric, open-label, randomised controlled exploratory trial was conducted at seven study sites under the Central Council for Research in Homoeopathy. Participants fulfilling the eligibility criteria were enrolled. The primary outcome was to evaluate changes in Low-Density Lipoprotein cholesterol at months 3 and 6. Secondary outcomes were to evaluate changes in total cholesterol, triglyceride, …


Role Of Homoeopathic Treatment For Symptom Management And Improving Quality Of Life In Severe Psoriatic Disease: A Case Report, Kapil Das, Gautam Pal Mar 2025

Role Of Homoeopathic Treatment For Symptom Management And Improving Quality Of Life In Severe Psoriatic Disease: A Case Report, Kapil Das, Gautam Pal

Indian Journal of Research in Homoeopathy

Introduction: Psoriasis and Psoriatic Arthritis (PsA) are the main phenotypes of psoriatic disease. PsA is a chronic inflammatory arthritis, associated with psoriasis that can cause joint damage and can severely impact a patient’s quality of life (QoL).

Case Summary: A 21-yearold male suffering from PsA for three years presented in the outpatient department. He was previously treated with different methods of treatment without much relief. Clinically along with psoriatic rash, patient reported swelling, pain and stiffness of joints, causing restriction of movement. In addition, patient also presented with ophthalmic and gastric complaints. After a thorough clinical evaluation, Phosphorus in increasing …


Management Of Epilepsy With Individualised Homoeopathic Medicine Lachesis In Millesimal Potency: An Evidence-Based Case Report, Jayashree Nanda, Sujata Choudhury Mar 2025

Management Of Epilepsy With Individualised Homoeopathic Medicine Lachesis In Millesimal Potency: An Evidence-Based Case Report, Jayashree Nanda, Sujata Choudhury

Indian Journal of Research in Homoeopathy

Introduction: Epilepsy can be defined as a seizure disorder due to a change in electric activity in the brain which comprises a variety of disorders due to underlying brain dysfunction which increases the pre-disposition for seizures. It is a serious public health problem that affects the normal activity and quality of life of an individual. Homoeopathic medicines are successfully used for the treatment of epilepsy. Hence, research is needed with documentation of well-defined case reports. Here we present a case of epilepsy which was cured by individualised homoeopathic medicine after repertorisation.

Case summary: A 52-year-old male presented with complaints of …


The Ethics Of Homoeopathy: Addressing The Role Of Patient Testimonials Versus Scientific Evidence, Parth Aphale, Himanshu Shekhar, Shashank Dokania Mar 2025

The Ethics Of Homoeopathy: Addressing The Role Of Patient Testimonials Versus Scientific Evidence, Parth Aphale, Himanshu Shekhar, Shashank Dokania

Indian Journal of Research in Homoeopathy

Letter to the Editor


Book Review On ‘Chronic Miasms In Homoeopathy’, P. Dastagiri Mar 2025

Book Review On ‘Chronic Miasms In Homoeopathy’, P. Dastagiri

Indian Journal of Research in Homoeopathy

Book Review


Role Of Carcinosinum In Managing Separation Anxiety Disorder In Children: A Case Report, Karunakara Moorthi, Pranjali Srivastava Mar 2025

Role Of Carcinosinum In Managing Separation Anxiety Disorder In Children: A Case Report, Karunakara Moorthi, Pranjali Srivastava

Indian Journal of Research in Homoeopathy

Introduction: Separation Anxiety Disorder (SAD) is a condition causing excessive and distressing anxiety about separating from home or loved ones. It starts in childhood or adolescence and continues into adulthood. Symptoms include constant worry about losing a parent or other loved one to an illness or disaster, constant fear that something bad will happen, refusing to be away from home due to fear of separation, reluctance to sleep without a parent or a loved one nearby and repeated nightmares about separation.

Case Summary: A 7-year-old boy presented with symptoms of anxiety when going to school, weeping before going to school, …


Ijrh’S Journey: So Far And What Lies Ahead, Subhash Kaushik Mar 2025

Ijrh’S Journey: So Far And What Lies Ahead, Subhash Kaushik

Indian Journal of Research in Homoeopathy

Editorial


Research Highlights, Shruti Jain Vij, Charu Sehgal Mar 2025

Research Highlights, Shruti Jain Vij, Charu Sehgal

Indian Journal of Research in Homoeopathy

Research Highlights


Phytochemical Analysis And In Vivo Anticancer Effect Of Becium Grandiflorum: Isolation And Characterization Of A Promising Cytotoxic Diterpene, Christeen Fahim, Maha R. A. Abdollah, Rola Milad, Nehal Sabry, Noha Swilam Mar 2025

Phytochemical Analysis And In Vivo Anticancer Effect Of Becium Grandiflorum: Isolation And Characterization Of A Promising Cytotoxic Diterpene, Christeen Fahim, Maha R. A. Abdollah, Rola Milad, Nehal Sabry, Noha Swilam

Pharmacy

Background:Becium grandiflorum is a fragrant perennial shrub of the Lamiaceae family. Objectives: The current study aimed to explore the cytotoxic potential of the nhexane fraction from Becium grandiflorum aerial parts and, further, isolate its major diterpene and conduct in vitro and in vivo anticancer activities along with its molecular mechanism and synergy with doxorubicin. Methods: The hydroalcoholic extract of Becium grandiflorum aerial parts was fractionated, and the n-hexane fraction was analyzed via GC-MS. The major isolated diterpene, 18-epoxy-pimara-8(14),15-diene (epoxy-pimaradiene), was quantified using UPLC-PDA. Cytotoxicity assays were conducted on HCT-116, MCF-7, MDA-MB- 231, and HepG2 cell lines. The synergistic effect with …


Optimizing Interventions For Major Depressive Disorder And Provider Burnout: Self-Speak Exercise Dosing (Sed), Laureen Maloney-Gepfert Mar 2025

Optimizing Interventions For Major Depressive Disorder And Provider Burnout: Self-Speak Exercise Dosing (Sed), Laureen Maloney-Gepfert

Lynchburg Journal of Medical Science

ABSTRACT

Major Depressive Disorder (MDD) is ranked highest among mental illnesses in the United States (US) and significantly contributes to the mental health care crisis. Patients experience resistance to pharmacologic interventions, side effects, co-morbidities, and mental health provider shortages. Subsequently, 33 % of Serious Mental Illnesses (SMIs) are being redirected to Primary Care Providers (PCPs). Concurrently, prescriber mental health is in crisis. Growing workloads for physicians and Advanced Practice Providers (APPs) have increased provider burnout syndrome (BOS). Major Depressive Disorder and BOS are positively affected by exercise, Cognitive Restructuring (CR), and Behavioral Activation (BA). Sports medicine and psychology research shows …


Grounded In Touch: The Science Behind Anxiety Relief And Human Connection, Misty Rhoads Ph.D. Czb, Mary Murphy M.A., Lmt, Czb, Mary L. Behrens Pt, Czb, Rhonda Salvo Pt, Czb, Sarah-Elizabeth Anderson Lmt, Czb, Clare Gowen Pt, Czb, Dawn Humbles Lsh, Czb, Veronica Quarry Pt, Czb, Deborah Rosene Ph.D., Czb, Wendy Tribelhorn Lmt, Czb, Jared Urcheck L.Ac, Czb, Deanna Waggy Otr, Czb Mar 2025

Grounded In Touch: The Science Behind Anxiety Relief And Human Connection, Misty Rhoads Ph.D. Czb, Mary Murphy M.A., Lmt, Czb, Mary L. Behrens Pt, Czb, Rhonda Salvo Pt, Czb, Sarah-Elizabeth Anderson Lmt, Czb, Clare Gowen Pt, Czb, Dawn Humbles Lsh, Czb, Veronica Quarry Pt, Czb, Deborah Rosene Ph.D., Czb, Wendy Tribelhorn Lmt, Czb, Jared Urcheck L.Ac, Czb, Deanna Waggy Otr, Czb

Journal of Transformative Touch

Background: Anxiety disorders are among the most pervasive mental health challenges worldwide, affecting individuals across all demographics and socioeconomic backgrounds. As a leading contributor to disability and diminished quality of life, anxiety continues to rise in prevalence, exacerbated by global crises and societal stressors. This study explored how Zero Balancing (ZB) supports individuals with anxiety. Researchers hypothesized that ZB would lower the perceived severity of general anxiety and reduce perceived anxiety symptoms.

Methods: A concurrent mixed-methods phenomenological research design was utilized to honor the holistic nature of bodywork and explore participants' lived experiences. This national study involved 320 ZB sessions …


Antioxidant And Chemotherapeutic Synergy: Triphala Enhances Doxorubicin Cytotoxicity In Breast Cancer Cells And Reduces Toxicity In Non-Tumorigenic Cells, Supamas Charucharana, Poonlarp Cheepsunthorn Ph.D., Chalisa Louicharoen Cheepsunthorn Ph.D. Mar 2025

Antioxidant And Chemotherapeutic Synergy: Triphala Enhances Doxorubicin Cytotoxicity In Breast Cancer Cells And Reduces Toxicity In Non-Tumorigenic Cells, Supamas Charucharana, Poonlarp Cheepsunthorn Ph.D., Chalisa Louicharoen Cheepsunthorn Ph.D.

Chulalongkorn Medical Journal

Background: The combining of antioxidants with chemotherapy is increasingly explored to minimize toxicity in non-cancerous cells during breast cancer treatment. Triphala (TPL), a Thai herbal compound rich in antioxidants, shows potential as a complementary candidate for breast cancer chemotherapy.

Objective: This study investigated the combined effects of TPL and low-dose doxorubicin (DOX) on human breast cancer and non-tumorigenic mammary epithelial cells.

Methods: TPL’s bioactive compounds were analyzed via high-performance liquid chromatography (HPLC). Cell viability and reactive oxygen species (ROS) levels were assessed in breast cancer (MDA-MB-231, MCF-7) and epithelial (MCF-10A) cells using thiazolyl blue tetrazolium bromide (MTT) and chloromethyl 2′,7′-dichlorodihydrofluorescein …


Short-Term Effects Of Self-Thai Foot Massage And Foot Care On Balance And Proprioception Among Patients With Diabetic Peripheral Neuropathy, Saw Mya Soe, Sawitri Wanpen, Thiwabhorn Thaweewannakit, Punnee Peungsuwan, Uraiwan Chatchawan Mar 2025

Short-Term Effects Of Self-Thai Foot Massage And Foot Care On Balance And Proprioception Among Patients With Diabetic Peripheral Neuropathy, Saw Mya Soe, Sawitri Wanpen, Thiwabhorn Thaweewannakit, Punnee Peungsuwan, Uraiwan Chatchawan

Journal of Health Research

Background: Diabetic foot care involves complications such as impaired balance and proprioception, which can impact a patient's quality of life. This study investigated the short-term effects of self-administered Thai Foot Massage (STFM) on balance and proprioception in diabetic patients.

Methods: A randomized controlled trial was employed; ninety diabetic peripheral neuropathy (DPN) participants were randomly assigned to receive either STFM combined with standard foot care (STFM-SFC) or standard foot care alone (SFC). The intervention spanned four weeks, with two weeks at the hospital followed by an additional two weeks at home. Outcome measures included assessments of balance using the …


Exploring Cucurbitacin D'S Protective Mechanism Against Benzo[A]Pyrene-Induced Liver Injury Through Nrf2 Activation, Shabnam Malik, Mohammed Sikander, Anyssa Rodriguiez, Daniel Zubieta, Debanhi Esparaza, Fathi T. Halaweish, Sheema Khan, Murali M. Yallapu, Meena Jaggi, Subhash C. Chauhan Mar 2025

Exploring Cucurbitacin D'S Protective Mechanism Against Benzo[A]Pyrene-Induced Liver Injury Through Nrf2 Activation, Shabnam Malik, Mohammed Sikander, Anyssa Rodriguiez, Daniel Zubieta, Debanhi Esparaza, Fathi T. Halaweish, Sheema Khan, Murali M. Yallapu, Meena Jaggi, Subhash C. Chauhan

Research Symposium

Background: Numerous studies have established a strong association between hepatocellular carcinoma (HCC) and various co-morbidity factors, including smoking. Tobacco smoke is a significant source of benzo[a]pyrene, a highly carcinogenic compound known to cause liver damage. Cucurbitacin, a triterpene with diverse biological activities, exhibits antioxidant, antiinflammatory, and anticancer effects. However, its hepatoprotective properties have not been thoroughly investigated. In this study, we aimed to evaluate the hepatoprotective effects of cucurbitacin D, a novel analog of cucurbitacin, against liver injury induced by benzo[a]pyrene in human HepG2 cells.

Method: To investigate the hepatoprotective effect of cucurbitacin D against benzo[a]pyreneinduced liver damage, proliferation, clonogenicity, …


Evaluating The Potential Of Herbal Extracts As Treatment In Immune Thrombocytopenia: A Review Of Evidence And Limitations, Russell Wiggins, Jihoo Woo, John Cauba, Shizue Mito Mar 2025

Evaluating The Potential Of Herbal Extracts As Treatment In Immune Thrombocytopenia: A Review Of Evidence And Limitations, Russell Wiggins, Jihoo Woo, John Cauba, Shizue Mito

Research Symposium

Immune thrombocytopenia, formerly idiopathic thrombocytopenia purpura (ITP), is an autoimmune disease characterized by the depletion of platelets below 100,000/µl when other causes of thrombocytopenia have been ruled out. It is associated with several infectious pathologies, disease states, and as a known side effect and complication of several drugs and chemotherapies. Standard treatment calls for glucocorticoid mediated immunosuppression, intravenous immunoglobin transfusion, platelet stimulation, platelet transfusion, and splenectomy in instances of chronic and severe disease. While standard treatments are often effective, some cases prove resistant, and more commonly, some patients are unable to tolerate standard treatment protocols or opt out of surgical …


Ormeloxifene-Mediated Attenuation Of Β-Catenin Signaling In Hepatocellular Carcinoma Progression, Mohammed Sikander, Shabnam Malik, Daniel Zubieta, Anyssa Rodriguez, Molly Vela, Sheema Khan, Fathi T. Halaweish, Murali M. Yallapu, Meena Jaggi, Subhash C. Chauhan Mar 2025

Ormeloxifene-Mediated Attenuation Of Β-Catenin Signaling In Hepatocellular Carcinoma Progression, Mohammed Sikander, Shabnam Malik, Daniel Zubieta, Anyssa Rodriguez, Molly Vela, Sheema Khan, Fathi T. Halaweish, Murali M. Yallapu, Meena Jaggi, Subhash C. Chauhan

Research Symposium

Background: Hepatocellular carcinoma (HCC) is the most prevalent form of primary liver cancer, with approximately 41,000 new cases and 29,000 deaths annually in the U.S. The management of HCC poses significant challenges due to severe toxicity and inadequate responses to existing chemotherapeutic agents. Aberrant β-catenin signaling is recognized as a crucial factor influencing the differentiation grades of HCC patients. Therefore, there is an urgent need to identify more effective and non-toxic β-catenin inhibitors for cancer treatment. Notably, ormeloxifene (ORM), a clinically approved selective estrogen receptor modulator with a favorable therapeutic index, has demonstrated remarkable anticancer activity, making it a promising …


Cardiometabolic Benefits Of A Non-Industrialized-Type Diet Are Linked To Gut Microbiome Modulation, Fuyong Li, Anissa M. Armet, Katri Korpela, Junhong Liu, Rodrigo Margain Quevedo, Francesco Asnicar, Benjamin Seethaler, Tianna B. S. Rusnak, Janis L. Cole, Zhihong Zhang, Shuang Zhao, Adele Gagnon, Edward C. Deehan, Joao F. Mota, Jeffrey A. Bakal, Russell Greiner, Dan Knights, Nicola Segata, Stephan C. Bischoff, Laurie Mereu, Andrea M. Haqq, Catherine J. Field, Liang Li, Carla M. Prado, Jens Walter Mar 2025

Cardiometabolic Benefits Of A Non-Industrialized-Type Diet Are Linked To Gut Microbiome Modulation, Fuyong Li, Anissa M. Armet, Katri Korpela, Junhong Liu, Rodrigo Margain Quevedo, Francesco Asnicar, Benjamin Seethaler, Tianna B. S. Rusnak, Janis L. Cole, Zhihong Zhang, Shuang Zhao, Adele Gagnon, Edward C. Deehan, Joao F. Mota, Jeffrey A. Bakal, Russell Greiner, Dan Knights, Nicola Segata, Stephan C. Bischoff, Laurie Mereu, Andrea M. Haqq, Catherine J. Field, Liang Li, Carla M. Prado, Jens Walter

Department of Food Science and Technology: Faculty Publications

Industrialization adversely affects the gut microbiome and predisposes individuals to chronic non-communicable diseases. We tested a microbiome restoration strategy comprising a diet that recapitulated key characteristics of non-industrialized dietary patterns (restore diet) and a bacterium rarely found in industrialized microbiomes (Limosilactobacillus reuteri) in a randomized controlled feeding trial in healthy Canadian adults. The restore diet, despite reducing gut microbiome diversity, enhanced the persistence of L. reuteri strain from rural Papua New Guinea (PB-W1) and redressed several microbiome features altered by industrialization. The diet also beneficially altered microbiota-derived plasma metabolites implicated in the etiology of chronic non-communicable diseases. Considerable …


The Science Behind Alternative Medicine: Using Natural Compounds To Battle Cancer, Amanda Focht Mar 2025

The Science Behind Alternative Medicine: Using Natural Compounds To Battle Cancer, Amanda Focht

Osmosis Magazine

In the middle ages essential oils were valued for their various Medicinal properties as well as their potent fragrances. Recent years have demonstrated a renewed interest in these compounds and their potential uses in modern medecine.


A Review Of Key Music Therapy Approaches To Unlocking Recovery From Stroke And Traumatic Brain Injury, Bethany Woolman, Nina Mourao, Joshua K. Elliott, Shizue Mito, Ney Alliey-Rodriguez Mar 2025

A Review Of Key Music Therapy Approaches To Unlocking Recovery From Stroke And Traumatic Brain Injury, Bethany Woolman, Nina Mourao, Joshua K. Elliott, Shizue Mito, Ney Alliey-Rodriguez

Research Symposium

Background: Strokes and traumatic brain injuries are neuronal injuries that can impact the motor, sensory, and cognitive abilities of an affected individual, and may necessitate therapy of multiple forms to regain back total or partial functionality and independence in their daily lives. Music assists in stimulating multiple brain regions, and when incorporated into rehabilitation, it has the potential to impact stroke and traumatic brain injury recovery. This literature review focuses on the efficacy of two novel music therapy approaches, melodic intonation therapy (MIT) and rhythmic auditory stimulation (RAS), on recovery from aphasia and restoration of gait, respectively, to assess whether …


The Use Of Hyperbaric Oxygen Therapy In The Setting Of Acute Limb Ischemia, Josue Fonseca, Andrew B. Callan Mar 2025

The Use Of Hyperbaric Oxygen Therapy In The Setting Of Acute Limb Ischemia, Josue Fonseca, Andrew B. Callan

Research Symposium

Background: Hyperbaric oxygen therapy is a long-used yet understudied intervention for a wide array of conditions. In the case of our patient with acute limb ischemia secondary to cholesterol emboli, the use of hyperbaric oxygen therapy after attempted thrombectomy and thrombolysis was utilized to promote tissue oxygenation and wound healing with the goal of preserving the patient’s limb. What makes this case novel is that an understudied treatment method was used to preserve the patient’s limb after the recommended treatment options been exhausted. This case highlights the need for more studies on the effectiveness of hyperbaric oxygen therapy in the …


Reducing Burnout Among Physiatry Trainees During The Pandemic: Instituting A Wellness Retreat, Edwin Amirianfar, Oliver Acosta, Eduard Tiozzo, Joslyn Gober, Monica Verduzco-Gutierrez Feb 2025

Reducing Burnout Among Physiatry Trainees During The Pandemic: Instituting A Wellness Retreat, Edwin Amirianfar, Oliver Acosta, Eduard Tiozzo, Joslyn Gober, Monica Verduzco-Gutierrez

Journal of Wellness

Introduction: Burnout has been described as “a state of mental and physical exhaustion related to work or caregiving activities.” Among resident physicians, burnout is a serious concern that can lead to medical errors and negative patient outcomes. To combat burnout among physiatry trainees during the COVID-19 pandemic, an innovative wellness retreat was created and implemented at the University of Miami’s Physical Medicine and Rehabilitation (PM&R) Residency Program in March 2021 and February 2022.

Methods: The retreat curriculum was designed by the PM&R Residency Wellness Committee and supported by departmental funding. The retreat(s) consisted of three strategies: education and discussion on …


Role Of Urolithin A In Cancer Therapy, Aanya S. Chauhan, Vinita Karumuru, Mahi P. Yallapu, Anupam Dhasmana Feb 2025

Role Of Urolithin A In Cancer Therapy, Aanya S. Chauhan, Vinita Karumuru, Mahi P. Yallapu, Anupam Dhasmana

Research Symposium

Background: Cancer is a big health problem around the world, causing many deaths even though there have been improvements in treatments. Some of the main challenges in treating cancer include side effects, resistance to treatments, cancer spreading to other parts of the body (metastasis), and the disease coming back (recurrence). Scientists are looking for safer and better ways to treat cancer. One promising option is using natural substances that come from plants, which are less toxic and have a lot of potential for fighting diseases. One of these substances is Urolithin A (UA), a compound made in the body when …


Exploring The Therapeutic Potential Of Barbaloin: A Wonder Constituent From Aloe Vera Plant, Akanksha Andhare, Kranti Satpute, Shoaeb Mohammad Syed Feb 2025

Exploring The Therapeutic Potential Of Barbaloin: A Wonder Constituent From Aloe Vera Plant, Akanksha Andhare, Kranti Satpute, Shoaeb Mohammad Syed

International Journal of Health and Allied Sciences

The aim of current study was to explore chemistry and therapeutic potential of barbaloin. A detailed literature review was carried out at various data bases such as PubMed, Elsevier, Springer, Wiley, Taylor & Francis, etc. The healing plant aloe emodin's main compound is barbaloin (C21H22O9), anthrone's C-glucoside. The Liliace family includes perennial succulent aloe vera. Barbaloin, a pale-yellow aloe vera powder, is a first-group glucoside of the alove emodin anthrone molecule. Barbaloin has anti-inflammatory, cathartic, antiviral, antibacterial, and antioxidant qualities that prevent cancer. Barbaloin also improves cardiovascular health, test perception, enzyme metabolism, and bioavailability. Barbaloin may help treat eczema, psoriasis, …