Medicine and Health Sciences Commons^™

Cooperative Extension In Urban America: Place-Based Approaches For Improving Health, Dawn Burton, Latoya O'Neal, Erin Yelland, Suzanne Stluka, Rodger Rennekamp

Journal of Human Sciences and Extension

While the bulk of Cooperative Extension’s (Extension) historical work has been with rural populations, its future work should also address the needs of those living in urban areas. The opportunity to live a long and healthy life is paramount among those needs. Cooperative Extension’ National Framework for Health Equity and Well-Being (Framework) provides a roadmap by which Cooperative Extension can help ensure that all people have that opportunity. The central premise of the Framework is that future work of Extension must include but extend beyond the promotion of healthy behaviors to place-based approaches for improving conditions in which people live, …

Reconceptualizing Youth Sparks: A Sociocultural Approach To Co-Designing Programs For Somali Youth, Joanna A. Tzenis

Journal of Human Sciences and Extension

The 4-H Youth Development Program has a long history of fostering positive youth outcomes. Recently, attention and resources have been invested in the development of a program model (i.e., the 4-H Thriving Model) that theorizes the program elements that lead to positive outcomes (Arnold, 2018). Less attention, however, has been given to the program design process by which and with whom 4-H programs are designed and implemented. This matters because a lack of a community-engaged design process may lead to outcomes disconnected from community self-interests or to the exclusion of youth who might view the program as irrelevant to their …

Book Review – The Art Of Being Indispensable At Work: Win Influence, Beat Overcommitment, And Get The Right Things Done, Eric Killian

Journal of Human Sciences and Extension

With new technology, constant change, uncertainty, and virtual teams, getting things done at work is tougher and more complex than ever. Finding your place amid the collaboration revolution working with everyone across silos and various platforms can feel like we are in a no-win cycle in urban Extension environments. However, there is always the indispensable go-to person, or in our case organization—urban Extension, that thrives on many working relationships, maintains a positive attitude of service, demonstrates creativity and tenacity, and strives to get the right things done. This review will share information on how urban Extension professionals can continue to …

Fostering A Sense Of Belonging In Urban Extension For Internal And External Stakeholders, Ramona Madhosingh-Hector, Linda M. Seals

Journal of Human Sciences and Extension

In urban areas, the communities are as diverse as the issues, and different educational and engagement strategies must be deployed to support urban Extension clientele. Urban communities must connect with and feel a sense of “belonging” with Extension–this connection can strengthen Extension’s presence and value proposition to urban constituents. This study found that although Extension was engaged in efforts to support belonging, its efforts were hampered by a lack of collaboration and commitment to supporting a system-wide effort to change the culture. Intentionality, emotional intelligence, and dialogue were presented as strategies to foster a sense of belonging for Extension personnel …

Futuring Perspectives And Practices For Urban Extension, Julie Fox, Solomon Garner

Journal of Human Sciences and Extension

Extension is well-positioned to engage strategically with urban communities now and in the future. A century of collaboration and proven impact provides Extension with a valuable foundation focused on relevant service accessible to all people; applied science and co-discovery; respectful and inclusive engagement; and commitment to community well-being. An exploration of the literature on the future, from the Extension perspective and from external viewpoints, informs a contemporary approach to focus on the future of urban Extension. An interplay of Extension professionals with diverse community stakeholders and dynamic technologies bridges past perspective and current context with practical methods to address the …

Exploring School Staff Perceptions Relating To Animals And Their Involvement In Interventions To Support Mental Health, Rhoda A Leos, Paula M Cuccaro, John R Herbold, Belinda F Hernandez

Faculty, Staff and Student Publications

Given the growing awareness of the health benefits of human-animal interactions, the use of animal-assisted interventions (AAIs) in educational settings has increased over the years. While many school districts are now considering or utilizing AAIs, the literature investigating AAI-related perceptions among school stakeholders is limited with previous studies focusing on evaluating specific programs. to address this gap, a qualitative exploratory study was conducted using semi-structured interviews with school staff in the San Antonio, TX community. A total of 11 interviews were completed with staff serving preschool and elementary school age children. Data collected from interviews were analyzed using thematic analysis. …

Onboarding And Orientation Of Advanced Practice Providers In Metropolitan, Tracie Clisby

College of Science and Health Theses and Dissertations

Background: Advanced Practice Providers (APPs) are imperative in the provision of care within emergency departments. The employment of APPs requires an onboarding and orientation process to their respective facility. Employees undergoing onboarding and orientation to a new job have shown increased employee satisfaction and retention thereby reducing turnover and financial and non-financial costs associated with turnover.

Purpose: To describe the formal orientation and onboarding programs of APPs working in academic medical center emergency departments (EDs) of United States metropolitan cities.

Method: A qualitative descriptive design was utilized for this study using open-ended questions. Individual semi-structured interviews were conducted with APP …

Systemic Ablation Of Camkk2 Impairs Metastatic Colonization And Improves Insulin Sensitivity In Tramp Mice: Evidence For Cancer Cell-Extrinsic Camkk2 Functions In Prostate Cancer, Thomas L Pulliam, Dominik Awad, Jenny J Han, Mollianne M Murray, Jeffrey J Ackroyd, Pavithr Goli, Jonathan S Oakhill, John W Scott, Michael M Ittmann, Daniel E Frigo

Faculty, Staff and Students Publications

Despite early studies linking calcium-calmodulin protein kinase kinase 2 (CAMKK2) to prostate cancer cell migration and invasion, the role of CAMKK2 in metastasis in vivo remains unclear. Moreover, while CAMKK2 is known to regulate systemic metabolism, whether CAMKK2's effects on whole-body metabolism would impact prostate cancer progression and/or related comorbidities is not known. Here, we demonstrate that germline ablation of

Maternal And Fetal Bile Acid Homeostasis Regulated By Sulfated Progesterone Metabolites Through Fxr Signaling Pathway In A Pregnant Sow Model, Peng Wang, Peiqiang Yuan, Sen Lin, Heju Zhong, Xiaoling Zhang, Yong Zhuo, Jian Li, Lianqiang Che, Bin Feng, Yan Lin, Shengyu Xu, De Wu, Douglas G Burrin, Zhengfeng Fang

Faculty, Staff and Students Publications

Abnormally elevated circulating bile acids (BA) during pregnancy endanger fetal survival and offspring health; however, the pathology and underlying mechanisms are poorly understood. A total of nineteen pregnant sows were randomly assigned to day 60 of gestation, day 90 of gestation (G60, G90), and the farrowing day (L0), to investigate the intercorrelation of reproductive hormone, including estradiol, progesterone and sulfated progesterone metabolites (PMSs), and BA in the peripheral blood of mother and fetuses during pregnancy. All data were analyzed by Student’s t-test or one-way ANOVA of GraphPad Prism and further compared by using the Student–Newman–Keuls test. Correlation analysis was …

Antibody-Mediated Lilrb2-Receptor Antagonism Induces Human Myeloid-Derived Suppressor Cells To Kill Mycobacterium Tuberculosis, Vipul K. Singh, Arshad Khan, Yitian Xu, Sunny Mai, Licheng Zhang, Abhishek Mishra, Blanca I. Restrepo, Ping-Ying Pan, Shu-Hsia Chen

School of Medicine Publications

Tuberculosis is a leading cause of death in mankind due to infectious agents, and Mycobacterium tuberculosis (Mtb) infects and survives in macrophages (MФs). Although MФs are a major niche, myeloid-derived suppressor cells (MDSCs) are an alternative site for pathogen persistence. Both MФs and MDSCs express varying levels of leukocyte immunoglobulin-like receptor B (LILRB), which regulate the myeloid cell suppressive function. Herein, we demonstrate that antagonism of LILRB2 by a monoclonal antibody (mab) induced a switch of human MDSCs towards an M1-macrophage phenotype, increasing the killing of intracellular Mtb. Mab-mediated antagonism of LILRB2 alone and its combination with a pharmacological blockade …

Pluteus Insidiosus Complex, Four New Species Described And Pluteus Reisneri Resurrected, Hana Ševčíková, Giuliano Ferisin, Ekaterina Malysheva, Alfredo Justo, Jacob Heilmann-Clausen, Egon Horak, Lyudmila Kalinina, Oğuzhan Kaygusuz, Henning Knudsen, Nelson Menolli, Pierre-Arthur Moreau, Guillermo Muñoz González, Irja Saar, İbrahim Türkekul, Francesco Dovana

Faculty, Staff and Students Publications

We studied the taxonomy of Pluteus insidiosus and similar species using morphological and molecular (nrITS, TEF1-α) data, including a detailed study of the type collection of P. insidiosus. Based on our results, we recognize five species in this group: P. insidiosus sensu stricto and four other taxa: P. assimilatus; P. farensis; P. flavostipitatus; and P. pseudoinsidiosus; described here as new. All these taxa are distinct from each other based on molecular data, but some of them are semi-cryptic based on morphology and co-occur in the Palaearctic region. An additional molecular lineage, phylogenetically separates from the P. …

Atr-Mediated Cd47 And Pd-L1 Up-Regulation Restricts Radiotherapy-Induced Immune Prming And Abscopal Responses In Colorectal Cancer, Rodney Cheng-En Hsieh, Sunil Krishnan, Ren-Chin Wu, Akash R Boda, Arthur Liu, Michelle Winkler, Wen-Hao Hsu, Steven Hsesheng Lin, Mien-Chie Hung, Li-Chuan Chan, Krithikaa Rajkumar Bhanu, Anupallavi Srinivasamani, Ricardo Alexandre De Azevedo, Yung-Chih Chou, Ronald A Depinho, Matthew Gubin, Eduardo Vilar, Chao Hsien Chen, Ravaen Slay, Priyamvada Jayaprakash, Shweta Mahendra Hegde, Genevieve Hartley, Spencer T Lea, Rishika Prasad, Brittany Morrow, Coline Agnes Couillault, Madeline Steiner, Chun-Chieh Wang, Bhanu Prasad Venkatesulu, Cullen Taniguchi, Yon Son Betty Kim, Junjie Chen, Nils-Petter Rudqvist, Michael A Curran

Faculty, Staff and Student Publications

Radiotherapy (RT) of colorectal cancer (CRC) can prime adaptive immunity against tumor-associated antigen (TAA)-expressing CRC cells systemically. However, abscopal tumor remissions are extremely rare, and the postirradiation immune escape mechanisms in CRC remain elusive. Here, we found that irradiated CRC cells used ATR-mediated DNA repair signaling pathway to up-regulate both CD47 and PD-L1, which through engagement of SIRPα and PD-1, respectively, prevented phagocytosis by antigen-presenting cells and thereby limited TAA cross-presentation and innate immune activation. This postirradiation CD47 and PD-L1 up-regulation was observed across various human solid tumor cells. Concordantly, rectal cancer patients with poor responses to neoadjuvant RT exhibited …

Pharmacometabolomics Profiling Of Preterm Infants Validates Patterns Of Metabolism Associated With Response To Dexamethasone Treatment For Bronchopulmonary Dysplasia., Bradley Stockard, Cheri Gauldin, William E. Truog, Tamorah Lewis

Manuscripts, Articles, Book Chapters and Other Papers

Bronchopulmonary dysplasia (BPD) is one of the most common health complications of premature birth. Corticosteroids are commonly used for treatment of BPD, but their use is challenging due to variability in treatment response. Previous pharmacometabolomics study has established patterns of metabolite levels with response to dexamethasone. We obtained additional patient samples for metabolomics analysis to find associations between the metabolome and dexamethasone response in a validation cohort. A total of 14 infants provided 15 plasma and 12 urine samples. The measure of treatment response was the calculated change in respiratory severity score (deltaRSS) from pre-to-post treatment. Each metabolite was assessed …

A Reference Tissue Atlas For The Human Kidney, Jens Hansen, Sanjay Jain, Et Al

2020-Current year OA Pubs

Kidney Precision Medicine Project (KPMP) is building a spatially specified human kidney tissue atlas in health and disease with single-cell resolution. Here, we describe the construction of an integrated reference map of cells, pathways, and genes using unaffected regions of nephrectomy tissues and undiseased human biopsies from 56 adult subjects. We use single-cell/nucleus transcriptomics, subsegmental laser microdissection transcriptomics and proteomics, near-single-cell proteomics, 3D and CODEX imaging, and spatial metabolomics to hierarchically identify genes, pathways, and cells. Integrated data from these different technologies coherently identify cell types/subtypes within different nephron segments and the interstitium. These profiles describe cell-level functional organization of …

Genome-Wide Crispr Screens Using Isogenic Cells Reveal Vulnerabilities Conferred By Loss Of Tumor Suppressors, Rodney Cheng-En Hsieh, Sunil Krishnan, Ren-Chin Wu, Akash R Boda, Arthur Liu, Michelle Winkler, Wen-Hao Hsu, Steven Hsesheng Lin, Mien-Chie Hung, Li-Chuan Chan, Krithikaa Rajkumar Bhanu, Anupallavi Srinivasamani, Ricardo Alexandre De Azevedo, Yung-Chih Chou, Ronald A Depinho, Matthew Gubin, Eduardo Vilar, Chao Hsien Chen, Ravaen Slay, Priyamvada Jayaprakash, Shweta Mahendra Hegde, Genevieve Hartley, Spencer T Lea, Rishika Prasad, Brittany Morrow, Coline Agnes Couillault, Madeline Steiner, Chun-Chieh Wang, Bhanu Prasad Venkatesulu, Cullen Taniguchi, Yon Son Betty Kim, Junjie Chen, Nils-Petter Rudqvist, Michael A Curran

Faculty, Staff and Student Publications

Radiotherapy (RT) of colorectal cancer (CRC) can prime adaptive immunity against tumor-associated antigen (TAA)-expressing CRC cells systemically. However, abscopal tumor remissions are extremely rare, and the postirradiation immune escape mechanisms in CRC remain elusive. Here, we found that irradiated CRC cells used ATR-mediated DNA repair signaling pathway to up-regulate both CD47 and PD-L1, which through engagement of SIRPα and PD-1, respectively, prevented phagocytosis by antigen-presenting cells and thereby limited TAA cross-presentation and innate immune activation. This postirradiation CD47 and PD-L1 up-regulation was observed across various human solid tumor cells. Concordantly, rectal cancer patients with poor responses to neoadjuvant RT exhibited …

Risk Of Peritoneal Carcinomatosis After Risk-Reducing Salpingo-Oophorectomy: A Systematic Review And Individual Patient Data Meta-Analysis, Miranda P Steenbeek, Majke H D Van Bommel, Johan Bulten, Julia A Hulsmann, Joep Bogaerts, Christine Garcia, Han T Cun, Karen H Lu, Heleen J Van Beekhuizen, Lucas Minig, Katja N Gaarenstroom, Marielle Nobbenhuis, Mateja Krajc, Vilius Rudaitis, Barbara M Norquist, Elizabeth M Swisher, Marian J E Mourits, Leon F A G Massuger, Nicoline Hoogerbrugge, Rosella P M G Hermens, Joanna Inthout, Joanne A De Hullu

Faculty, Staff and Student Publications

Purpose: After risk-reducing salpingo-oophorectomy (RRSO), BRCA1/2 pathogenic variant (PV) carriers have a residual risk to develop peritoneal carcinomatosis (PC). The etiology of PC is not yet clarified, but may be related to serous tubal intraepithelial carcinoma (STIC), the postulated origin for high-grade serous cancer. In this systematic review and individual patient data meta-analysis, we investigate the risk of PC in women with and without STIC at RRSO.

Methods: Unpublished data from three centers were supplemented by studies identified in a systematic review of EMBASE, MEDLINE, and the Cochrane library describing women with a BRCA-PV with and without …

Genomic Aberrations In Circulating Tumor Dnas From Palbociclib-Treated Metastatic Breast Cancer Patients Reveal A Novel Resistance Mechanism., Maysa Abu-Khalaf, Chun Wang, Zhenchao Zhang, Rui Luo, Weelic Chong, Daniel P. Silver, Frederick Fellin, Rebecca J. Jaslow, Ana Maria Lopez, Md, Mph, Macp, Terrence Cescon, Wei Jiang, Md, Phd, Ronald E. Myers, Phd, Dsw, Qiang Wei, Bingshan Li, Massimo Cristofanilli, Hushan Yang

Department of Medical Oncology Faculty Papers

Previously undescribed molecular mechanisms of resistance will emerge with the increased use of cyclin-dependent kinase 4/6 inhibitors in clinical settings. To identify genomic aberrations in circulating tumor DNA associated with treatment resistance in palbociclib-treated metastatic breast cancer (MBC) patients, we collected 35 pre- and post-treatment blood samples from 16 patients with estrogen receptor-positive (ER

Investigating The Covid-19 Pandemic In Your Community, Tanzina Ahmed

Open Educational Resources

In this writing assignment, students will conduct research on statistics about COVID-19 in New York City and their embedded communities using free online databases from the New York City Department of Health (NYC DOH). For questions 1, 2, 3, and 4, students will conduct research on COVID-19 statistics within NYC and their specific neighborhood/community in New York City. In questions 5 and 6, students will analyze the data you have gathered while using your own knowledge of your community. A full set of instructions for accessing NYC DOH databases and a complete rubric for grading the assignment is included.

College Of Health Professions News, Georgia Southern University

College of Health Professions: News & Publications (2012-2023)

• Georgia Southern Alumni Pledge $125,000 for Tormenta FC Endowed Scholarship

Development Of A Core Measurement Set For Research In Degenerative Cervical Myelopathy: A Study Protocol (Ao Spine Recode-Dcm Cms), Benjamin M Davies, Alvaro Yanez Touzet, Oliver D Mowforth, Keng Siang Lee, Danyal Khan, Julio C Furlan, Michael G Fehlings, James Harrop, Carl Moritz Zipser, Ricardo Rodrigues-Pinto, James Milligan, Ellen Sarewitz, Armin Curt, Vafa Rahimi-Movaghar, Bizhan Aarabi, Timothy F Boerger, Lindsay Tetreault, Robert Chen, James D Guest, Sukhvinder Kalsi-Ryan, Iwan Sadler, Shirley Widdop, Angus G K Mcnair, Brian K Kwon, Mark R N Kotter

Department of Neurosurgery Faculty Papers

Introduction: Progress in degenerative cervical myelopathy (DCM) is hindered by inconsistent measurement and reporting. This impedes data aggregation and outcome comparison across studies. This limitation can be reversed by developing a core measurement set (CMS) for DCM research. Previously, the AO Spine Research Objectives and Common Data Elements for DCM (AO Spine RECODE-DCM) defined 'what' should be measured in DCM: the next step of this initiative is to determine 'how' to measure these features. This protocol outlines the steps necessary for the development of a CMS for DCM research and audit.

Methods and analysis: The CMS will be developed in …

Context Matters: Preliminary Evidence That The Association Between Positive Affect And Adiposity In Infancy Varies In Social Vs Non-Social Situations, Alexis C Wood, Shabnam R Momin, Mackenzie K Senn, David J Bridgett

Children’s Nutrition Research Center Staff Publications

Previous studies have suggested that infants high in negative affect have higher levels of adiposity, arising in part via changes in nutrition (e.g., “feeding to soothe”). Few studies have examined whether positive affect shows similar or inverse associations with adiposity. The current study examined cross-sectional and longitudinal relationships between adiposity and observations of positive affect in both a social and a non-social context, using data from infants at four (n = 125) and 12 (n = 80) months of age. Our analyses did not find any cross-sectional associations between positive affect and adiposity (all p > 0.05). However, in the longitudinal …

Tomatoes, Lycopene, And Prostate Cancer: What Have We Learned From Experimental Models?, Nancy E Moran, Jennifer M Thomas-Ahner, Lei Wan, Krystle E Zuniga, John W Erdman, Steven K Clinton

Children’s Nutrition Research Center Staff Publications

Human epidemiology suggests a protective effect of tomatoes or tomato phytochemicals, such as lycopene, on prostate cancer risk. However, human epidemiology alone cannot reveal causal relations. Laboratory animal models of prostate cancer provide opportunities to investigate hypotheses regarding dietary components in precisely controlled, experimental systems, contributing to our understanding of diet and cancer risk relations. We review the published studies evaluating the impact of tomatoes and/or lycopene in preclinical models of prostate carcinogenesis and tumorigenesis. The feeding of tomatoes or tomato components demonstrates anti-prostate cancer activity in both transplantable xenograft models of tumorigenesis and models of chemically- and genetically-driven carcinogenesis. …

Inequalities In The Prevalence Of Full Immunization Coverage Among One-Year-Olds In Ghana, 1993–2014, Eugene Budu, Bright Opoku Ahinkorah, Joshua Okyere, Abdul-Aziz Seidu, Henry Ofori Duah

College of Nursing Faculty Research and Publications

Background

We examined the inequalities in the prevalence of full immunization coverage among one-year-olds in Ghana using nationally representative data from the 1993-2014 Ghana Demographic and Health Surveys (GDHSs).

Methods

Using the World Health Organization’s (WHO) Health Equity Assessment Toolkit (HEAT) software, data from the 1993–2014 GDHSs were analyzed. We disaggregated full immunization by five equity stratifiers: wealth quintile, education, sex, residence, and region. Second, we measured the inequality through summary measures, namely Difference, Population Attributable Risk, Ratio, and Population Attributable Fraction. Statistical significance was pegged at 95% Uncertainty Interval.

Results

From 1993 to 2014, full immunization was higher among …

Challenges Created By The Covid-19 Pandemic: Pediatric Emergency Medicine And Disaster Management Perspectives, Thomas E Tanner, Nichole R Davis, Brent D Kaziny, Erin E Endom, Esther M Sampayo

Faculty, Staff and Students Publications

OBJECTIVE: The coronavirus disease (COVID-19) pandemic has presented unique challenges to pediatric emergency medicine (PEM) departments. The purpose of this study was to identify these challenges and ascertain how centers overcame barriers in creating solutions to continue to provide high-quality care and keep their workforce safe during the early pandemic.

METHODS: This is a qualitative study based on semi-structured interviews with physicians in leadership positions who have disaster or emergency management experience. Participants were identified through purposive sampling. Interviews were recorded and transcribed electronically. Themes and codes were extracted from the transcripts by 2 independent coders. Constant comparison analysis was …

Evolutionary Action Of Mutations Reveals Antimicrobial Resistance Genes In Escherichia Coli, David C Marciano, Chen Wang, Teng-Kuei Hsu, Thomas Bourquard, Benu Atri, Ralf B Nehring, Nicholas S Abel, Elizabeth A Bowling, Taylor J Chen, Pamela D Lurie, Panagiotis Katsonis, Susan M Rosenberg, Christophe Herman, Olivier Lichtarge

Faculty, Staff and Students Publications

Since antibiotic development lags, we search for potential drug targets through directed evolution experiments. A challenge is that many resistance genes hide in a noisy mutational background as mutator clones emerge in the adaptive population. Here, to overcome this noise, we quantify the impact of mutations through evolutionary action (EA). After sequencing ciprofloxacin or colistin resistance strains grown under different mutational regimes, we find that an elevated sum of the evolutionary action of mutations in a gene identifies known resistance drivers. This EA integration approach also suggests new antibiotic resistance genes which are then shown to provide a fitness advantage …

Resistance To Targeted Therapies: Delving Into Flt3 And Idh, Sai Prasad Desikan, Naval Daver, Courtney Dinardo, Tapan Kadia, Marina Konopleva, Farhad Ravandi

Faculty, Staff and Student Publications

Recent advances in FLT3 and IDH targeted inhibition have improved response rates and overall survival in patients with mutations affecting these respective proteins. Despite this success, resistance mechanisms have arisen including mutations that disrupt inhibitor-target interaction, mutations impacting alternate pathways, and changes in the microenvironment. Here we review the role of these proteins in leukemogenesis, their respective inhibitors, mechanisms of resistance, and briefly ongoing studies aimed at overcoming resistance.

Evaluation Of Colour Reproduction Of Cad/Cam Lithuim-Disilicate Veneers Of Different Thicknesses And Translucency, Sahar H. Fikry, Tarek Salah Morsi, Mennatallah M. Wahba, Amr El-Etreby

Future Dental Journal

Background: With the increasing patients’ demand for a perfect smile, the call for highly aesthetic and yet minimally invasive veneers has surmounted. Objective: The aim of this study was to evaluate the colour of CAD/CAM lithium disilicate veneers fabricated in different thicknesses and different translucencies of the lithium disilicate blocks. Materials and Methods: Forty discs of lithium disilicate glass-ceramic (IPS e.max CAD) of shade A1 of both high and low translucency (HT, LT) were tested for their colour reproduction. HT and low LT blocks were cut in the form of plates of dimensions (12 x 14 mm) and of different …

Effect Of Abutments Design On Wear Of Locator Attachments In Implant Retained Mandibular Overdenture., Mahmoud Saleh Fayed, Medhat Sameh Abdelaziz, Hossam I. Nassar

Future Dental Journal

Purpose: The aim of this study is to compare the effect of abutments design on wear behavior of Locator attachments in implant-retained mandibular overdenture. Materials and Methods: Two epoxy models representing an edentulous mandible were used, two implants were placed in each model. Twenty-four locator attachments were used (twelve in each study group). Cycles of Insertion and removal were performed using a universal testing machine resembling 3 years of clinical use, then each abutment was scanned by scanning electron microscope (SEM) before and after insertion and removal cycles. Data were compared qualitatively using a specialized computer software Results: There was …

Effect Of Various Sintering Protocols On The Translucency Of Highly Translucent Cubic Zirconia, Kerolos Salah Mehany, Ashraf Hussein Sherif, Shereen Ahmed Nossair, Mona Hossam El-Din Mandour

Future Dental Journal

Aim of the study: This study was carried out to evaluate the effect of various sintering protocols on the translucency of highly translucent cubic zirconia. Materials and methods: A total of forty discs of two types of zirconia ceramics were used in this study. The specimens were divided into two main groups according to the type of zirconia; Group 1 (n=20): Cubic zirconia (DD Cube X2 98color) and Group 2 (n=20): Tetragonal zirconia (BioZX2color). Each group was subdivided into two subgroups, where 10 discs were per subgroup according to the sintering protocol. Cubic and tetragonal zirconia blanks of dimensions (98 …

Management Of Post Covid 19 Mucormycosis With Osteomyelitis In The Maxilla, New Combined Consequences Of The Pandemic. (Case Report)., Hussein El Charkawi Proffesor, Omar A. El Sharkawy

Future Dental Journal

ABSTRACT:

Aim: This case report aims to demonstrate among health providers the importance of timely surgical and prosthetic management procedures of patients who suffered from the newly combined clinical entity of post COVID 19 mucormycosis and osteomyelitis of the palate. Materials and methods: Elaborate advanced diagnosis of the patients including CBCT, MRI, CT, Pathology examination, 3Ds printing reconstruction of the whole skull and digital design of reconstructive mesh that support the prosthesis were carried out. The patients undergone modified infrastructure maxillectomy and immediate prosthetic obturation of the palatal defect that was replaced later by a delayed obturator. Results: Surgical eradication …