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Articles 1 - 30 of 329
Full-Text Articles in Medicine and Health Sciences
Estimation Of The Factors Affecting Lactation Milk Yield Of Holstein Cattle By The Adaptiveneuro-Fuzzy Inference System, Aycan Mutlu Yağanoğlu
Estimation Of The Factors Affecting Lactation Milk Yield Of Holstein Cattle By The Adaptiveneuro-Fuzzy Inference System, Aycan Mutlu Yağanoğlu
Turkish Journal of Veterinary & Animal Sciences
The aim of this study is to estimate lactation milk yield of Holstein cattle using first calving age, lactation period, and service period with (ANFIS) adaptive neuro-fuzzy inference system. The input variables for the system in the study were first calving age, lactation period, and service period. The output variable from the system was lactation milk yield. Predicted values obtained from the ANFIS were compared with the observed values. Twenty-seven rule functions are used to obtain the best model and 1000 epochs are used to estimate the accuracy of the training and testing error. The relations between the output and …
The Effects Of Biological And Health Characteristics Of Dogs On Intraindividual Variabilityof Blood Parameters, Sandra Nikolic, Branislava Belic, Marko Cincovic, Nikolina Novakov, Nada Plavsa, Sara Savic
The Effects Of Biological And Health Characteristics Of Dogs On Intraindividual Variabilityof Blood Parameters, Sandra Nikolic, Branislava Belic, Marko Cincovic, Nikolina Novakov, Nada Plavsa, Sara Savic
Turkish Journal of Veterinary & Animal Sciences
Considering the great diversity among dogs and their different biological and health characteristics, as well as different treatment protocols, it has become important to assess the effects of these factors on intraindividual variability of blood parameters in dogs, which is the aim of this study. Blood samples were collected from one hundred client-owned dogs. The dogs were of different age, breed, sex, body condition, reproductive, and health status and were presented to the veterinary clinic for preventive or diagnostic procedures. The effect of age on intraindividual variation was significant for various blood parameters and it was essential to establish new …
The In Vitro Effect Of Hypochlorous Acid-Metal Nanoparticles Combination On Salmonellaunder Different Temperature Conditions, Serkan Kemal Büyükünal, Karlo Muratoğlu, Ahmet Koluman
The In Vitro Effect Of Hypochlorous Acid-Metal Nanoparticles Combination On Salmonellaunder Different Temperature Conditions, Serkan Kemal Büyükünal, Karlo Muratoğlu, Ahmet Koluman
Turkish Journal of Veterinary & Animal Sciences
Hypochlorous acid (HClO) is an excellent surface disinfectant and classified as nonhazardous but maintaining a steady HClO solution is extremely difficult. This study aimed to mix HClO with various metal nanoparticles (NPs) to improve stability. The efficiency of the prepared solutions against Salmonella Typhimurium, Salmonella Enteritidis, Salmonella Dublin, and Salmonella Infantis was assessed using the culture method in five distinct experimental groups at varying temperatures (4 °C, 10 °C, 25 °C, 40 °C, and 50 °C). The type of metal NPs, HClO, and application temperatures utilized in the combined solutions for bacterial decontamination did not result in a significant difference …
Nonscarring Scalp Alopecia: Which Laboratory Analysis Should We Perform On Whom?, Ümran Öner, Necmetti̇n Akdeni̇z
Nonscarring Scalp Alopecia: Which Laboratory Analysis Should We Perform On Whom?, Ümran Öner, Necmetti̇n Akdeni̇z
Turkish Journal of Medical Sciences
Background/aim: Vitamins and minerals are thought to play an essential but not entirely clear role in developing, preventing, and treating nonscarring alopecia. Telogen effluvium, androgenetic alopecia, and alopecia areata are the most common forms of nonscarring alopecias. We would like to present a different perspective on laboratory abnormalities in patients with nonscarring alopecia. Materials and methods: A total of 467 patients (287 females, 180 males) were included retrospectively: One hundred and sixty patients in the telogen effluvium group, 101 patients in the androgenetic alopecia group, 99 patients in the alopecia areata group, and 107 patients in the hair loss group …
Utility Of Etco2 To Predict Hemorrhagic Shock In Multiple Trauma Patients, Gülşen Öztürk Örmeci̇, Özlem Yi̇ği̇t, Oktay Eray
Utility Of Etco2 To Predict Hemorrhagic Shock In Multiple Trauma Patients, Gülşen Öztürk Örmeci̇, Özlem Yi̇ği̇t, Oktay Eray
Turkish Journal of Medical Sciences
Background/aim: For identifying hemorrhagic shock in trauma patients, some objective data are needed. The use of base excess (BE) and lactate values have been originated. In this study, it was aimed to determine the usability of end tidal carbon dioxide (ETCO2) in patients with multiple trauma for recognizing hemorrhagic shock. Materials and methods: Patients who were admitted to the emergency department between June 2019 and February 2020 with high- energy multiple trauma were included in the study. ETCO2 and BE values were measured. Correlation coefficients were calculated to determine correlations between ETCO2 and BE levels. Results: One hundred and twenty-two …
A High-Fat And High-Fructose Diet Lowers The Cecal Digesta's Weight And Short-Chain Fatty Acid Level Of A Sprague-Dawley Rat Model, Etik Sulistyowati, Dian Handayani, Setyawati Soeharto, Achmad Rudijanto
A High-Fat And High-Fructose Diet Lowers The Cecal Digesta's Weight And Short-Chain Fatty Acid Level Of A Sprague-Dawley Rat Model, Etik Sulistyowati, Dian Handayani, Setyawati Soeharto, Achmad Rudijanto
Turkish Journal of Medical Sciences
Background/aim: This study aimed to analyze the effect of a high-fat and high-fructose diet (HFFD) on the digesta weight and short- chain fatty acid (SCFA) levels of cecal digesta in rats. Materials and methods: This study was an experimental study with a posttest-only control group design with male Sprague-Dawley strain rats as the samples. A total of 36 rats were divided into two groups with normal diet (N) and modified HFFD. The data of energy intake, nutrients and fiber, body weight, Lee index, abdominal circumference, digesta weight, and SCFA levels of cecal digesta were collected. Results: The results showed an …
Tp-E Interval, Tp-E/Qt, And Tp-E/Qtc Ratios In Patients With Primaryhyperparathyroidism And Their Relationship With Cardiac Arrhythmic Events, Yücel Yilmaz, Şaban Keleşoğlu, Ferhat Gökay, Yasi̇n Şi̇mşek
Tp-E Interval, Tp-E/Qt, And Tp-E/Qtc Ratios In Patients With Primaryhyperparathyroidism And Their Relationship With Cardiac Arrhythmic Events, Yücel Yilmaz, Şaban Keleşoğlu, Ferhat Gökay, Yasi̇n Şi̇mşek
Turkish Journal of Medical Sciences
Background/aim: Primary hyperparathyroidism (PHPT) is an endocrine disorder characterized by hypercalcemia caused by excessive parathyroid hormone (PTH) secretion from the parathyroid gland. PHPT was previously shown to increase cardiac arrhythmias. Besides, new indices, such as the Tpeak-Tend (Tp-e) interval, Tp-e interval/QT interval (Tp-e/QT) ratio, and Tp-e interval/corrected QT interval (Tp-e/QTc) ratio may be associated with ventricular arrhythmias and sudden cardiac death. Therefore, we aimed to investigate the relationship between PHPT and the changes to Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio. Materials and methods: We carried out the study with 41 patients with PHPT and 40 control subjects. We calculated …
Additional Gastric Resection After One Anastomosis Gastric Bypass-Are There Benefits?, Haci Murat Çayci, Umut Eren Erdoğdu, Mehmet Aki̇f Türkoğlu, Ali̇ Tardu, Ufuk Arslan, Gözde Doğan, Hasan Çantay
Additional Gastric Resection After One Anastomosis Gastric Bypass-Are There Benefits?, Haci Murat Çayci, Umut Eren Erdoğdu, Mehmet Aki̇f Türkoğlu, Ali̇ Tardu, Ufuk Arslan, Gözde Doğan, Hasan Çantay
Turkish Journal of Medical Sciences
Background/aim: Mini/one anastomosis gastric bypass (MGB-OAGB) is a bariatric surgery procedure that has proved effective for weight loss and the resolution of metabolic disorders. The present study evaluates the effect on postoperative outcomes of resecting the corpus and fundus as an addition to OAGB. Materials and methods: This retrospective study recorded and evaluated the data of 83 patients who underwent laparoscopic OAGB due to morbid obesity (Body Mass Index-BMI ≥ 40 kg/m2 ) in our clinic between January 2018 and January 2020. The patients were divided into two groups: the first group comprised patients undergoing standard OAGB (n = 49), …
The Efficacy Of Anakinra Compared To Standard Care Of Treatment For Covid-19: A Metaanalysis, Hamna Malik, Hira Bint Abdul Jabbar, Farah Latif, Azza Sarfraz, Zouina Sarfraz, Muzna Sarfraz
The Efficacy Of Anakinra Compared To Standard Care Of Treatment For Covid-19: A Metaanalysis, Hamna Malik, Hira Bint Abdul Jabbar, Farah Latif, Azza Sarfraz, Zouina Sarfraz, Muzna Sarfraz
Turkish Journal of Medical Sciences
Background/aim: As SARS-CoV-2 continues to spread worldwide, this study brings to light the link that anakinra, a recombinant IL-1 receptor antagonist, has in averting grave clinical outcomes. The objectives of this meta-analysis are to investigate the effects of anakinra in interventional groups compared to control/standard of care groups on mortality along with the provision of a prevalence estimate of the variables associated with death (C-reactive protein-CRP, ferritin, acute respiratory distress syndrome-ARDS). Materials and methods: According to the PRISMA 2020 statement guidelines, a systematic search was conducted from December 19, 2020, until December 10, 2021, with keywords including COVID-19, coronavirus, SARS-CoV-2, …
Arthroscopic Bankart Repair Improves Upper Limb Exercise Capacity, Shoulder Function And Quality Of Life, Fi̇gen Dağ, Fehmi̇ Volkan Öztuna, Di̇dem Deri̇ci̇ Yildirim, Özlem Bölgen Çi̇men
Arthroscopic Bankart Repair Improves Upper Limb Exercise Capacity, Shoulder Function And Quality Of Life, Fi̇gen Dağ, Fehmi̇ Volkan Öztuna, Di̇dem Deri̇ci̇ Yildirim, Özlem Bölgen Çi̇men
Turkish Journal of Medical Sciences
No abstract provided.
Determination Of Mirna Expression Profile In Patients With Prostate Cancer And Benign Prostate Hyperplasia, Okan Sancer, Pinar Aslan Koşar, Muhammet Yusuf Tepebaşi, Osman Ergün, Murat Demi̇r, Ali̇m Koşar
Determination Of Mirna Expression Profile In Patients With Prostate Cancer And Benign Prostate Hyperplasia, Okan Sancer, Pinar Aslan Koşar, Muhammet Yusuf Tepebaşi, Osman Ergün, Murat Demi̇r, Ali̇m Koşar
Turkish Journal of Medical Sciences
No abstract provided.
Assessment Of Tp-E Interval, Tp-E/Qt And Tp-E/Qtc Ratios In Patients With Acromegaly, İbrahi̇m Etem Çeli̇k, Sevde Nur Firat, Uğur Bozkurt, Mi̇kai̇l Yarloğlueş, Mustafa Duran, Sani̇ Namik Murat
Assessment Of Tp-E Interval, Tp-E/Qt And Tp-E/Qtc Ratios In Patients With Acromegaly, İbrahi̇m Etem Çeli̇k, Sevde Nur Firat, Uğur Bozkurt, Mi̇kai̇l Yarloğlueş, Mustafa Duran, Sani̇ Namik Murat
Turkish Journal of Medical Sciences
No abstract provided.
Cross-Sectional Study Of Middle East Respiratory Syndrome Coronavirus In Humans And Dromedary Camels In Diyala, Iraq, Abdulrazak Hasan, Kareem Ali, Mohammad Saleh
Cross-Sectional Study Of Middle East Respiratory Syndrome Coronavirus In Humans And Dromedary Camels In Diyala, Iraq, Abdulrazak Hasan, Kareem Ali, Mohammad Saleh
Turkish Journal of Medical Sciences
Background/aim: Middle East respiratory syndrome (MERS) is a zoonotic viral disease transmitted from dromedaries to humans. To date, more than 1500 cases of MERS have been reported and 80% of all cases have occurred in the Kingdom of Saudi Arabia (KSA). T his cross-sectional study was carried out to figure out the rate of infection among humans and dromedary camels and to explore the risk factors. Materials and methods: This study was conducted in Diyala Province, Iraq for the period from August 2017 to October 2018. Human subjects included 90 participants; 34 (37.8%) were females and 56 (62.2%) were males. …
Determination Of Cardiovascular Risk In 192,711 Underweight And Normal Weight Workers, Bárbara Altisench Jané, José Ignacio Ramírez Manent, Sebastiana Arroyo Bote, Pere Riutord Sbert, Hilda María González San Miguel, Angel Arturo Lopez Gonzalez
Determination Of Cardiovascular Risk In 192,711 Underweight And Normal Weight Workers, Bárbara Altisench Jané, José Ignacio Ramírez Manent, Sebastiana Arroyo Bote, Pere Riutord Sbert, Hilda María González San Miguel, Angel Arturo Lopez Gonzalez
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the prevalence of cardiovascular risk factors (CVRF) and the level of cardiovascular risk (CVR), determined with different scales (REGICOR, SCORE, ERICE, vascular age...) in people with low and normal weight. Materials and Methods: A total of 192,711 underweight and normal weight Spanish workers participated. CVR parameters included were weight, abdominal circumference, blood pressure, glycemia (high >125 mg/dL or under hypoglycemic treatment) and lipids (cutoff points: total cholesterol 200 mg/dL, LDL 130 mg/dL, triglycerides 150 mg/dL) were obtained by automated enzymatic methods. Body mass index (BMI) was calculated, considering underweight 18.5 and …
Nucleolus Assessment In Invasive Breast Carcinoma, An Objective Parameter For Histological Grading, Seda Duman Öztürk, Çi̇ğdem Öztürk, Oğuzhan Okcu, Bayram Şen, Recep Bedi̇r
Nucleolus Assessment In Invasive Breast Carcinoma, An Objective Parameter For Histological Grading, Seda Duman Öztürk, Çi̇ğdem Öztürk, Oğuzhan Okcu, Bayram Şen, Recep Bedi̇r
Turkish Journal of Medical Sciences
Background/aim: The nucleolus has the potential to provide insight into how many types of cancer will progress. In this study, we examined the evaluation of the nucleolus with a microscope in widespread breast cancer tumors and whether this value contributes to tumor grading as an objective clinicopathological parameter. Materials and methods: In our study, the nucleolus was evaluated retrospectively in resections with a diagnosis of invasive breast carcinoma of the cases between January 2010 and April 2021. In total, the tumor nucleolus of 377 cases of invasive breast carcinoma was evaluated. Nucleolus evaluation was performed with light microscopy using four …
Association Of Thiol/Disulphide Homeostasis With Bethesda Classification Of Thyroid Nodules And Thyroid Cancer, Muhammet Cüneyt Bi̇lgi̇ner, Abbas Ali̇ Tam, Sevgül Faki, Bağdagül Yüksel Güler, Özcan Erel, İbrahi̇m Kilinç, Di̇dem Özdemi̇r, Oya Topaloğlu, Reyhan Ersoy, Beki̇r Çakir
Association Of Thiol/Disulphide Homeostasis With Bethesda Classification Of Thyroid Nodules And Thyroid Cancer, Muhammet Cüneyt Bi̇lgi̇ner, Abbas Ali̇ Tam, Sevgül Faki, Bağdagül Yüksel Güler, Özcan Erel, İbrahi̇m Kilinç, Di̇dem Özdemi̇r, Oya Topaloğlu, Reyhan Ersoy, Beki̇r Çakir
Turkish Journal of Medical Sciences
Background/aim: Ultrasonography and fine-needle aspiration biopsy are frequently used to diagnose thyroid cancer. However, supportive data might be required in case of diagnostic difficulty. This study investigated whether there is a relationship between thiol/ disulphide homeostasis and cytological and histopathological diagnosis of thyroid nodules. Materials and methods: The patient group consisted of 81 individuals with euthyroid nodular (single/multiple) goiter scheduled for thyroidectomy, and the control group consisted of 28 age- and sex-matched healthy volunteers who had no thyroid nodule on ultrasonographic evaluation. All participants were selected among the admissions to the study clinic between June 2017 and June 2018, and …
Correlations Between Glycosylated Hemoglobin And Glucose Levels In Chinese Older Adults With Newly Diagnosed Type 2 Diabetes Mellitus, Yun Yu, Jun Yang, Wei Tang
Correlations Between Glycosylated Hemoglobin And Glucose Levels In Chinese Older Adults With Newly Diagnosed Type 2 Diabetes Mellitus, Yun Yu, Jun Yang, Wei Tang
Turkish Journal of Medical Sciences
Background/aim: To explore the correlations between glycosylated hemoglobin (HbA1c) and glucose levels in older adults with newly diagnosed type 2 diabetes mellitus (T2DM). Materials and methods: A total of 783 participants aged ≥60 years were enrolled. The 75-g oral glucose tolerance test (OGTT) was conducted and HbA1c was measured. The participants were divided into normal glucose tolerance (NGT)HbA1c, Pre-DMHbA1c, and T2DMHbA1c groups based on the HbA1c diagnostic criteria. The correlations between HbA1c and glucose levels of the OGTT were analyzed. Results: When HbA1c ≥ 6.5% in older people, HbA1c was positively correlated with Glucose 0 min and 120 min of …
Percutaneous Transhepatic Management Of Biliary Strictures In Patients With Dysfunctioning Plastic Biliary Endoprostheses, Umut Öğüşlü, Gürkan Danişan, Burçak Gümüş
Percutaneous Transhepatic Management Of Biliary Strictures In Patients With Dysfunctioning Plastic Biliary Endoprostheses, Umut Öğüşlü, Gürkan Danişan, Burçak Gümüş
Turkish Journal of Medical Sciences
Background/aim: To evaluate the safety and outcomes of percutaneous transhepatic management of dysfunctioning plastic biliary endoprostheses (PBE) in patients with benign/malign biliary strictures. Materials and methods: Twenty-nine patients (22 men, 7 women; mean age of 60.7 (range 33-88) years) diagnosed with dysfunctioning PBE were included. Percutaneous transhepatic biliary drainage and subsequent PBE dislodgment into the bowel were performed in all cases. Patient demographics, etiology of the biliary stricture, indication, technical success, complications, and clinical outcomes were gleaned from medical records. Results: Seventeen patients had malignant strictures, while 12 patients had benign conditions. A total of 36 PBE (33 straight, 3 …
Cerebrospinal Fluid Level Of Neurofilament Light Chain Is Associated With Increased Disease Activity In Neuro-Behçet's Disease, Zerri̇n Karaaslan, Eli̇f Şanli, Özlem Ti̇mi̇rci̇ Kahraman, Vuslat Yilmaz, Ece Akbayir, Gi̇zem Koral, Sema İçöz, Tuncay Gündüz, Cem İsmai̇l Küçükali̇, Murat Kürtüncü, Erdem Tüzün
Cerebrospinal Fluid Level Of Neurofilament Light Chain Is Associated With Increased Disease Activity In Neuro-Behçet's Disease, Zerri̇n Karaaslan, Eli̇f Şanli, Özlem Ti̇mi̇rci̇ Kahraman, Vuslat Yilmaz, Ece Akbayir, Gi̇zem Koral, Sema İçöz, Tuncay Gündüz, Cem İsmai̇l Küçükali̇, Murat Kürtüncü, Erdem Tüzün
Turkish Journal of Medical Sciences
Background/aim: Clinical exacerbations characterized with neurological symptoms are observed in around 10% of Behçet's disease (BD) patients and may culminate in severe disability. Although certain immunological factors have been associated with disease activity in neuro-Behçet's disease (NBD), biomarkers for monitoring the clinical outcome of NBD have not been properly investigated. Materials and methods: Levels of neurofilament light chain (NFL), homeobox protein Hox-B3 (HoxB3), and YKL-40 were measured in cerebrospinal fluid (CSF) samples of 23 parenchymal (n = 16) and nonparenchymal (n = 7) NBD patients obtained during NBD attacks by ELISA. Parameters of clinical progression and outcome were assessed for …
Examination Of Diaphragm Thickness, Mobility And Thickening Fraction In Individuals With Copd Of Different Severity, Ceyhun Topcuoğlu, Eylem Tütün Yümi̇n, Mustafa Hizal, Suat Konuk
Examination Of Diaphragm Thickness, Mobility And Thickening Fraction In Individuals With Copd Of Different Severity, Ceyhun Topcuoğlu, Eylem Tütün Yümi̇n, Mustafa Hizal, Suat Konuk
Turkish Journal of Medical Sciences
Background/aim: Diaphragm thickness and mobility assessed by ultrasound in individuals with Chronic Obstructive Pulmonary Disease (COPD) reflect the function of the diaphragm. The aim of this study is to compare the diaphragm thickness, mobility, and thickening fraction in individuals with COPD of different severity and healthy individuals and examine the relationship between these parameters and pulmonary function test parameters. Materials and methods: A cross-sectional observational study design was used. Thirty individuals (mild = 11; moderate = 13; severe = 6) with COPD and 29 healthy male individuals aged between 40-75 years were included in the study. The individuals included in …
Effect Of Cell Salvage On Bleeding, Transfusion Of Blood Products, And Bleeding Parameters In Patients Undergoing Liver Transplantation With Intraoperative Massive Blood Transfusion, Tümay Uludağ Yanaral, Peli̇n Karaaslan
Effect Of Cell Salvage On Bleeding, Transfusion Of Blood Products, And Bleeding Parameters In Patients Undergoing Liver Transplantation With Intraoperative Massive Blood Transfusion, Tümay Uludağ Yanaral, Peli̇n Karaaslan
Turkish Journal of Medical Sciences
Background/aim: Autologous transfusion using a cell saver system has been used in liver transplantation with controversial outcomes. Its efficiency in patients with massive intraoperative transfusion has not been studied yet. This study aimed to evaluate effect of cell salvage (CS) on intraoperative bleeding and transfusion practices in liver transplantation with massive intraoperative transfusion. Materials and methods: Consecutive patients aged ≥18 years with intraoperative massive blood transfusion (≥ 6 units) between March 2014 and September 2020 were included. Patients subjected to CS were grouped as CS, whereas other patients were grouped as control. Number of transfused red blood cells was study's …
Morphometric Examination Of Trigeminal Nerve And Its Adjacent Structures In Patients With Trigeminal Neuralgia: A Case-Control Study, Yunus Emre Kundakci, Nadi̇re Ünver Doğan, İnci̇ Kara, Mehmet Öztürk, Zeli̇ha Fazlioğullari, Ahmet Kağan Karabulut
Morphometric Examination Of Trigeminal Nerve And Its Adjacent Structures In Patients With Trigeminal Neuralgia: A Case-Control Study, Yunus Emre Kundakci, Nadi̇re Ünver Doğan, İnci̇ Kara, Mehmet Öztürk, Zeli̇ha Fazlioğullari, Ahmet Kağan Karabulut
Turkish Journal of Medical Sciences
Background/aim: Morphological differences that can lead the trigeminal nerve to neurovascular conflict and a new solitary pontine lesion are associated with the pathogenesis of trigeminal neuralgia (TN). In this case-control study, we aimed to contribute to the current discussions about the pathogenesis of TN by investigating the anatomical structures that may have an effect on the morphometric parameters of the trigeminal nerve. Materials and methods: This study included 25 patients with TN followed up for pain in the Department of Algology, Faculty of Medicine, and 25 age- and gender-matched controls. We performed morphometric measurements including the length and volume of …
Effect Of Tocilizumab On Intensive Care Patients With Covid-19 Pneumonia, A Retrospective Cohort Study, Mehtap Pehli̇vanlar Küçük, Ahmet Oğuzhan Küçük, Ayşegül Pehli̇vanlar, Emi̇ne Sevi̇l Ayaydin Mürtezaoğlu, Kadi̇r Çoban, Gamze Kiliç, Olcay Ayçi̇çek, Funda Öztuna, Yilmaz Bülbül, Tevfi̇k Özlü
Effect Of Tocilizumab On Intensive Care Patients With Covid-19 Pneumonia, A Retrospective Cohort Study, Mehtap Pehli̇vanlar Küçük, Ahmet Oğuzhan Küçük, Ayşegül Pehli̇vanlar, Emi̇ne Sevi̇l Ayaydin Mürtezaoğlu, Kadi̇r Çoban, Gamze Kiliç, Olcay Ayçi̇çek, Funda Öztuna, Yilmaz Bülbül, Tevfi̇k Özlü
Turkish Journal of Medical Sciences
Backround/aim: In this study, the efficacy of an IL-6 antagonist, Tocilizumab, administered in the early period was studied in intensive care patients with COVID-19 pneumonia followed by hypoxic and systemic inflammation not receiving mechanical ventilation support. Materials and methods: Patients with COVID-19 pneumonia who have signs of hypoxia and systemic inflammation and/or who have acute bilateral infiltrates on chest radiograph and who received tocilizumab treatment were compared with the patients who received standard medical therapy. Patients who were followed up with COVID-19 pneumonia and respiratory failure between March 2020 and March 2021 were retrospectively evaluated in the study. A 400 …
Return Visit Characteristics Of Sars-Cov-2 Pcr-Positive Cases In A Pediatric Emergency Department, Ni̇han Şik, Durgül Özdemi̇r, Murat Duman
Return Visit Characteristics Of Sars-Cov-2 Pcr-Positive Cases In A Pediatric Emergency Department, Ni̇han Şik, Durgül Özdemi̇r, Murat Duman
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to evaluate return visits to the pediatric emergency department (ED) for children who were detected to be positive for SARS-CoV-2 by polymerase chain reaction (PCR). Materials and methods: Between April 2, 2020, and January 20, 2021, children aged 0 to 18 years who were detected to be SARS-CoV-2 PCR-positive and discharged from the ED were evaluated. Among them, patients who returned to the ED within 14 days of quarantine were included in the study. For the first presentation and return visit, demographics, clinical findings, laboratory and radiologic investigations, and ward/pediatric intensive care unit …
Interstitial Lung Disease In Patients With Systemic Lupus Erythematosus: A Cohort Study, Naci̇ Şenkal, Esen Kiyan, Ali̇ Aslan Demi̇r, Yasemi̇n Yalçinkaya, Ahmet Gül, Murat İnanç, Mahdume Lale Öçal, Bahar Artim Esen
Interstitial Lung Disease In Patients With Systemic Lupus Erythematosus: A Cohort Study, Naci̇ Şenkal, Esen Kiyan, Ali̇ Aslan Demi̇r, Yasemi̇n Yalçinkaya, Ahmet Gül, Murat İnanç, Mahdume Lale Öçal, Bahar Artim Esen
Turkish Journal of Medical Sciences
Background/aim: Systemic lupus erythematosus (SLE) is an autoimmune disease with a variety of organ/system involvement. Respiratory system involvement is common in these patients and usually manifests itself by disorders of the lung parenchyma, pleura, pulmonary vasculature or diaphragm. In this study, we sought to determine the frequency of interstitial lung disease (ILD) in patients with SLE and associated risk factors. Materials and methods: Three hundred randomly chosen patients with SLE were included. Chest x-ray (CXR), lung spirometry and carbon monoxide diffusion test (DLCO) were performed. High-resolution thorax computed tomography (HRCT) was performed for a definite diagnosis of ILD. Results: Of …
Pleuroparenchymal Fibroelastosis In Systemic Sclerosis-Associated Interstitial Lung Disease, Alper Sari, Ömer Önder, Berkan Armağan, Ertuğrul Çağri Bölek, Bayram Fari̇soğullari, Emre Bi̇lgi̇n, Gözde Kübra Yardimci, Orhan Maci̇t Ariyürek, Ali̇ Akdoğan
Pleuroparenchymal Fibroelastosis In Systemic Sclerosis-Associated Interstitial Lung Disease, Alper Sari, Ömer Önder, Berkan Armağan, Ertuğrul Çağri Bölek, Bayram Fari̇soğullari, Emre Bi̇lgi̇n, Gözde Kübra Yardimci, Orhan Maci̇t Ariyürek, Ali̇ Akdoğan
Turkish Journal of Medical Sciences
Background/aim: To explore the frequency and clinical associations of radiologic pleuroparenchymal fibroelastosis (PPFE) in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD). Materials and methods: In this single-center retrospective study, high resolution computed tomography (HRCT) images of 105 patients with SSc-ILD were examined for the presence of PPFE. Demographic, clinical, laboratory, and pulmonary function test (PFT) data of patients with and without PPFE were compared. Results: PPFE was detected in 19 (18.1%) patients (`definite PPFE' in 13 and `consistent with PPFE' in 6 patients). Patients with PPFE had higher age and longer disease duration than PPFE (-) patients (p < 0.05 for both). Radiologic usual interstitial pneumoniae (UIP) pattern was more frequent (26.3% vs. 4.7%, p = 0.01) and median force vital capacity (FVC) was lower in patients with PPFE (64% vs. 82%, p = 0.005). Spontaneous pneumothorax developed in one patient with PPFE. More deaths occured in PPFE (+) group during follow-up (31% vs. 11%, p = 0.04). Conclusion: PPFE on HRCT is not uncommon in SSc-ILD and is associated with radiologic UIP pattern and worse lung functions. Further studies are needed to elucidate the prognostic value of PPFE in SSc-ILD.
The Effects Of A Combination Treatment With Mesenchymal Stem Cell And Platelet-Rich Plasma On Tendon Healing: An Experimental Study, İlker Uyar, Zeynep Altuntaş, Siddika Findik, Mehmet Emi̇n Cem Yildirim, Serhat Yarar, Murat Aktan, Ahmet Avci
The Effects Of A Combination Treatment With Mesenchymal Stem Cell And Platelet-Rich Plasma On Tendon Healing: An Experimental Study, İlker Uyar, Zeynep Altuntaş, Siddika Findik, Mehmet Emi̇n Cem Yildirim, Serhat Yarar, Murat Aktan, Ahmet Avci
Turkish Journal of Medical Sciences
Background/Aim: The objective of this study was to investigate the effects that the application of mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP) following tendon repair have on the strength and healing of the tendon and also to examine the possible mechanisms of action that take place. Materials and methods: The Achilles tendons of 80 rats were repaired and divided into eight groups. Following the repairs, MSCs obtained from humans were injected into the rat tendons in groups 1 and 2, a combination of MSCs from humans and PRP from rats was injected into the tendons in groups 3 and …
Assessment Of Takayasu Arteritis In Routine Practice With Petvas, An 18f-Fdg Petquantitative Scoring Tool, Sema Kaymaz Tahra, Sali̇h Özgüven, Ali̇ Uğur Ünal, Fatma Ali̇baz Öner, Tunç Öneş, Tanju Yusuf Erdi̇l, Rafi̇ Haner Di̇reskeneli̇
Assessment Of Takayasu Arteritis In Routine Practice With Petvas, An 18f-Fdg Petquantitative Scoring Tool, Sema Kaymaz Tahra, Sali̇h Özgüven, Ali̇ Uğur Ünal, Fatma Ali̇baz Öner, Tunç Öneş, Tanju Yusuf Erdi̇l, Rafi̇ Haner Di̇reskeneli̇
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to evaluate the value of the PET vascular activity score (PETVAS) during the follow-up of patients with Takayasu arteritis. Materials and methods: Takayasu arteritis patients who underwent 18F-Fluorodeoxyglucose (FDG) PET imaging were evaluated retrospectively. In 8 patients both 1 and 2-h imagings were also performed prospectively. For PETVAS, 9 arterial areas were scored between 0-3 according to the FDG uptake. Results: Forty-six images of 34 patients were evaluated. PETVAS was higher in patients with clinically active disease (p = 0.03) and in the C-reactive protein (CRP) elevated group among clinically inactive patients (p …
A New Device For Bronchoscopy For Better Protection, Aslihan Gürün Kaya, Mi̇raç Öz, İnci̇fer Karnak Orhun, Serhat Erol, Aydin Çi̇ledağ, Demet Karnak, Akin Kaya
A New Device For Bronchoscopy For Better Protection, Aslihan Gürün Kaya, Mi̇raç Öz, İnci̇fer Karnak Orhun, Serhat Erol, Aydin Çi̇ledağ, Demet Karnak, Akin Kaya
Turkish Journal of Medical Sciences
Background/aim: During the COVID-19 pandemic, the risk of transmission of SARS-CoV-2 has not been precisely known in bronchoscopy procedures. We have designed a cabinet device called Ankara University Bronchoscopy Cabinet (Aubrocab® ) to protect healthcare. We aimed to evaluate preventing effect of Aubrocab® on aerosol spreading by measuring the particles in the bronchoscopy suite. Materials and methods: The patients were categorized into two groups as those who underwent bronchoscopy with and without Aubrocab® . We measured PM 0.5 levels before and after bronchoscopy in the bronchoscopy suite. Results: A total of 82 patients, 62 of whom underwent bronchoscopy with Aubrocab® …
Efficacy Of Eltrombopag In Thrombocytopenia After Hematopoietic Stem Celltransplantation, Ayşe Karataş, Hakan Göker, Haluk Demi̇roğlu, Ümi̇t Yavuz Malkan, Mustafa Velet, Olgu Erki̇n Çinar, Batuhan Erdoğdu, Mi̇ne Karadeni̇z, Ni̇lgün Sayinalp, Sali̇h Aksu, İbrahi̇m Celaletti̇n Haznedaroğlu, Osman İlhami̇ Özcebe, Yahya Büyükaşik
Efficacy Of Eltrombopag In Thrombocytopenia After Hematopoietic Stem Celltransplantation, Ayşe Karataş, Hakan Göker, Haluk Demi̇roğlu, Ümi̇t Yavuz Malkan, Mustafa Velet, Olgu Erki̇n Çinar, Batuhan Erdoğdu, Mi̇ne Karadeni̇z, Ni̇lgün Sayinalp, Sali̇h Aksu, İbrahi̇m Celaletti̇n Haznedaroğlu, Osman İlhami̇ Özcebe, Yahya Büyükaşik
Turkish Journal of Medical Sciences
Background/aim: Thrombocytopenia is a common complication following hematopoietic stem cell transplantation (HSCT). Eltrombopag has been used in thrombocytopenia treatment after HSCT in recent years. Herein, we present our experience of 25 patients treated with eltrombopag for post-HSCT thrombocytopenia. Materials and methods: Fifteen autologous hematopoietic stem cell transplantation (AHSCT) and 10 allogenic hematopoietic stem cell transplantation (allo-HSCT) recipients treated with eltrombopag for treatment of prolonged isolated thrombocytopenia (PIT) or secondary failure of platelet recovery (SFPR) in the stem cell transplantation unit of Hacettepe University Hematology Department between 2017 and 2021 were included in the study. The primary endpoint of this study …